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Search of human proteins with 6677723
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6677723 replication factor C 5 isoform 1 [Homo sapiens]
(340 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6677723 replication factor C 5 isoform 1 [Homo sapiens] 669 0.0
gi|194306571 replication factor C 5 isoform 2 [Homo sapiens] 625 e-179
gi|194306567 replication factor C 5 isoform 2 [Homo sapiens] 625 e-179
gi|194306569 replication factor C 5 isoform 3 [Homo sapiens] 498 e-141
gi|31881687 replication factor C 4 [Homo sapiens] 219 3e-57
gi|4506491 replication factor C 4 [Homo sapiens] 219 3e-57
gi|31563534 replication factor C 2 isoform 1 [Homo sapiens] 218 5e-57
gi|28882049 replication factor C 2 isoform 2 [Homo sapiens] 171 7e-43
gi|108773789 replication factor C 3 isoform 2 [Homo sapiens] 104 1e-22
gi|4506489 replication factor C 3 isoform 1 [Homo sapiens] 104 1e-22
gi|32528306 replication factor C large subunit [Homo sapiens] 61 1e-09
gi|19718796 RAD17 homolog isoform 1 [Homo sapiens] 54 2e-07
gi|19718794 RAD17 homolog isoform 1 [Homo sapiens] 54 2e-07
gi|19718792 RAD17 homolog isoform 1 [Homo sapiens] 54 2e-07
gi|19718784 RAD17 homolog isoform 1 [Homo sapiens] 54 2e-07
gi|4506383 RAD17 homolog isoform 1 [Homo sapiens] 54 2e-07
gi|19718786 RAD17 homolog isoform 2 [Homo sapiens] 54 2e-07
gi|27501458 CTF18, chromosome transmission fidelity factor 18 ho... 51 1e-06
gi|18426902 Werner helicase interacting protein isoform 1 [Homo ... 51 2e-06
gi|18426904 Werner helicase interacting protein isoform 2 [Homo ... 45 7e-05
gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens] 40 0.003
gi|4502703 cell division cycle 6 protein [Homo sapiens] 37 0.019
gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens] 37 0.025
gi|194018490 ATPase family, AAA domain containing 3C [Homo sapiens] 37 0.025
gi|119964730 BCS1-like [Homo sapiens] 35 0.074
gi|4757852 BCS1-like [Homo sapiens] 35 0.074
gi|75677353 AAA-ATPase TOB3 [Homo sapiens] 35 0.096
gi|21396489 mitochondrial lon peptidase 1 [Homo sapiens] 34 0.16
gi|31377667 peroxisomal LON protease-like [Homo sapiens] 34 0.21
gi|42476028 ATPase family, AAA domain containing 3A [Homo sapiens] 34 0.21
>gi|6677723 replication factor C 5 isoform 1 [Homo sapiens]
Length = 340
Score = 669 bits (1727), Expect = 0.0
Identities = 340/340 (100%), Positives = 340/340 (100%)
Query: 1 METSALKQQEQPAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYG 60
METSALKQQEQPAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYG
Sbjct: 1 METSALKQQEQPAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYG 60
Query: 61 PPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFK 120
PPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFK
Sbjct: 61 PPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFK 120
Query: 121 LVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPE 180
LVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPE
Sbjct: 121 LVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPE 180
Query: 181 LMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTG 240
LMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTG
Sbjct: 181 LMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTG 240
Query: 241 HPLKSDIANILDWMLNQDFTTAYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIH 300
HPLKSDIANILDWMLNQDFTTAYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIH
Sbjct: 241 HPLKSDIANILDWMLNQDFTTAYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIH 300
Query: 301 LLTKMADIEYRLSVGTNEKIQLSSLIAAFQVTRDLIVAEA 340
LLTKMADIEYRLSVGTNEKIQLSSLIAAFQVTRDLIVAEA
Sbjct: 301 LLTKMADIEYRLSVGTNEKIQLSSLIAAFQVTRDLIVAEA 340
>gi|194306571 replication factor C 5 isoform 2 [Homo sapiens]
Length = 319
Score = 625 bits (1613), Expect = e-179
Identities = 318/318 (100%), Positives = 318/318 (100%)
Query: 23 VEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKE 82
VEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKE
Sbjct: 2 VEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKE 61
Query: 83 FGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVI 142
FGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVI
Sbjct: 62 FGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVI 121
Query: 143 EKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGM 202
EKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGM
Sbjct: 122 EKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGM 181
Query: 203 KALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTA 262
KALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTA
Sbjct: 182 KALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTA 241
Query: 263 YRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQL 322
YRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQL
Sbjct: 242 YRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQL 301
Query: 323 SSLIAAFQVTRDLIVAEA 340
SSLIAAFQVTRDLIVAEA
Sbjct: 302 SSLIAAFQVTRDLIVAEA 319
>gi|194306567 replication factor C 5 isoform 2 [Homo sapiens]
Length = 319
Score = 625 bits (1613), Expect = e-179
Identities = 318/318 (100%), Positives = 318/318 (100%)
Query: 23 VEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKE 82
VEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKE
Sbjct: 2 VEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKE 61
Query: 83 FGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVI 142
FGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVI
Sbjct: 62 FGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVI 121
Query: 143 EKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGM 202
EKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGM
Sbjct: 122 EKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGM 181
Query: 203 KALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTA 262
KALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTA
Sbjct: 182 KALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTA 241
Query: 263 YRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQL 322
YRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQL
Sbjct: 242 YRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQL 301
Query: 323 SSLIAAFQVTRDLIVAEA 340
SSLIAAFQVTRDLIVAEA
Sbjct: 302 SSLIAAFQVTRDLIVAEA 319
>gi|194306569 replication factor C 5 isoform 3 [Homo sapiens]
Length = 255
Score = 498 bits (1283), Expect = e-141
Identities = 255/255 (100%), Positives = 255/255 (100%)
Query: 86 MVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVIEKF 145
MVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVIEKF
Sbjct: 1 MVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQNALRRVIEKF 60
Query: 146 TENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKAL 205
TENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKAL
Sbjct: 61 TENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKAL 120
Query: 206 VTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTAYRN 265
VTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTAYRN
Sbjct: 121 VTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANILDWMLNQDFTTAYRN 180
Query: 266 ITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQLSSL 325
ITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQLSSL
Sbjct: 181 ITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQLSSL 240
Query: 326 IAAFQVTRDLIVAEA 340
IAAFQVTRDLIVAEA
Sbjct: 241 IAAFQVTRDLIVAEA 255
>gi|31881687 replication factor C 4 [Homo sapiens]
Length = 363
Score = 219 bits (558), Expect = 3e-57
Identities = 125/321 (38%), Positives = 196/321 (61%), Gaps = 10/321 (3%)
Query: 16 KIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAK 75
K + +PWVEKYRP+ ++++ +++++ ++K + LP+LL YGPPGTGKTSTILA A+
Sbjct: 34 KAKPVPWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAAR 93
Query: 76 QLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKG-------FKLVILDEAD 128
+L+ + F VLELNASD+RGI ++R + +FA + FK+VILDEAD
Sbjct: 94 ELFGPELFRLRVLELNASDERGIQVVREKVKNFAQLTVSGSRSDGKPCPPFKIVILDEAD 153
Query: 129 AMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEH 188
+MT AQ ALRR +EK ++ TRFCLICNY+S+II L SRC++FRF PL+ ++ RL
Sbjct: 154 SMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLD 213
Query: 189 VVEEEKVDISEDGMKALVTLSSGDMRRALNILQS-TNMAFGK-VTEETVYTCTGHPLKSD 246
+ ++E V IS++G+ LV +S GD+R+A+ LQS T + GK +TE+ + G
Sbjct: 214 IAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGKEITEKVITDIAGVIPAEK 273
Query: 247 IANILDWMLNQDFTTAYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMA 306
I + + F + +L +G A ++ ++H V + + + K+A
Sbjct: 274 IDGVFAACQSGSFDKLEAVVKDLID-EGHAATQLVNQLHDVVVENNLSDKQKSIITEKLA 332
Query: 307 DIEYRLSVGTNEKIQLSSLIA 327
+++ L+ G +E +QL SL A
Sbjct: 333 EVDKCLADGADEHLQLISLCA 353
>gi|4506491 replication factor C 4 [Homo sapiens]
Length = 363
Score = 219 bits (558), Expect = 3e-57
Identities = 125/321 (38%), Positives = 196/321 (61%), Gaps = 10/321 (3%)
Query: 16 KIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAK 75
K + +PWVEKYRP+ ++++ +++++ ++K + LP+LL YGPPGTGKTSTILA A+
Sbjct: 34 KAKPVPWVEKYRPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAAR 93
Query: 76 QLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKG-------FKLVILDEAD 128
+L+ + F VLELNASD+RGI ++R + +FA + FK+VILDEAD
Sbjct: 94 ELFGPELFRLRVLELNASDERGIQVVREKVKNFAQLTVSGSRSDGKPCPPFKIVILDEAD 153
Query: 129 AMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEH 188
+MT AQ ALRR +EK ++ TRFCLICNY+S+II L SRC++FRF PL+ ++ RL
Sbjct: 154 SMTSAAQAALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKIQQQRLLD 213
Query: 189 VVEEEKVDISEDGMKALVTLSSGDMRRALNILQS-TNMAFGK-VTEETVYTCTGHPLKSD 246
+ ++E V IS++G+ LV +S GD+R+A+ LQS T + GK +TE+ + G
Sbjct: 214 IAKKENVKISDEGIAYLVKVSEGDLRKAITFLQSATRLTGGKEITEKVITDIAGVIPAEK 273
Query: 247 IANILDWMLNQDFTTAYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMA 306
I + + F + +L +G A ++ ++H V + + + K+A
Sbjct: 274 IDGVFAACQSGSFDKLEAVVKDLID-EGHAATQLVNQLHDVVVENNLSDKQKSIITEKLA 332
Query: 307 DIEYRLSVGTNEKIQLSSLIA 327
+++ L+ G +E +QL SL A
Sbjct: 333 EVDKCLADGADEHLQLISLCA 353
>gi|31563534 replication factor C 2 isoform 1 [Homo sapiens]
Length = 354
Score = 218 bits (556), Expect = 5e-57
Identities = 118/317 (37%), Positives = 187/317 (58%), Gaps = 3/317 (0%)
Query: 12 PAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTIL 71
P + LPWVEKYRP LN+++ ++D +S ++ F E +P++++ GPPGTGKT++IL
Sbjct: 28 PGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSIL 87
Query: 72 ACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKG-FKLVILDEADAM 130
A+ L +M LELNAS+DRGID++R I FA + KG K++ILDEAD+M
Sbjct: 88 CLARALLGPALKDAM-LELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSM 146
Query: 131 TQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVV 190
T AQ ALRR +E +++ TRF L CN KII +QSRC R+ LT ++ RL +V+
Sbjct: 147 TDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVI 206
Query: 191 EEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANI 250
E+E+V ++DG++A++ + GDMR+ALN LQST FG + E V+ P + +
Sbjct: 207 EKERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEM 266
Query: 251 LDWMLNQDFTTAYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEY 310
+ +N + AY+ + L L G + DI+ I +++ + ++
Sbjct: 267 IQHCVNANIDEAYKILAHLWHL-GYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHM 325
Query: 311 RLSVGTNEKIQLSSLIA 327
+++ G N +Q++ L+A
Sbjct: 326 KIAEGVNSLLQMAGLLA 342
>gi|28882049 replication factor C 2 isoform 2 [Homo sapiens]
Length = 320
Score = 171 bits (434), Expect = 7e-43
Identities = 100/316 (31%), Positives = 164/316 (51%), Gaps = 35/316 (11%)
Query: 12 PAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTIL 71
P + LPWVEKYRP LN+++ ++D +S ++ F E +P++++ GPPGTGKT++IL
Sbjct: 28 PGSAGHYELPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSIL 87
Query: 72 ACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMT 131
A+ L +LELNAS+ D+MT
Sbjct: 88 CLARALL-GPALKDAMLELNASN---------------------------------DSMT 113
Query: 132 QDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVE 191
AQ ALRR +E +++ TRF L CN KII +QSRC R+ LT ++ RL +V+E
Sbjct: 114 DGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQILTRLMNVIE 173
Query: 192 EEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDIANIL 251
+E+V ++DG++A++ + GDMR+ALN LQST FG + E V+ P + ++
Sbjct: 174 KERVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGFINSENVFKVCDEPHPLLVKEMI 233
Query: 252 DWMLNQDFTTAYRNITELKTLKGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYR 311
+N + AY+ + L L G + DI+ I +++ + ++ +
Sbjct: 234 QHCVNANIDEAYKILAHLWHL-GYSPEDIIGNIFRVCKTFQMAEYLKLEFIKEIGYTHMK 292
Query: 312 LSVGTNEKIQLSSLIA 327
++ G N +Q++ L+A
Sbjct: 293 IAEGVNSLLQMAGLLA 308
>gi|108773789 replication factor C 3 isoform 2 [Homo sapiens]
Length = 305
Score = 104 bits (259), Expect = 1e-22
Identities = 70/224 (31%), Positives = 114/224 (50%), Gaps = 28/224 (12%)
Query: 22 WVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLY--- 78
WV+KYRP +L L H++ + ++ + PHLL+YGP G GK + I+ ++LY
Sbjct: 4 WVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVG 63
Query: 79 ----------------KDKEFGSMV----LELNASDDRGID--IIRGPILSFASTR---T 113
K E ++ LE+N SD D +I+ + + A ++ T
Sbjct: 64 VEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLET 123
Query: 114 IFKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFR 173
++ FK+V+L E D +T+DAQ+ALRR +EK+ R L CN SK+IP ++SRC R
Sbjct: 124 NSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVR 183
Query: 174 FGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRAL 217
+ E + L V ++E +++ L S ++R+AL
Sbjct: 184 VPAPSIEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKAL 227
>gi|4506489 replication factor C 3 isoform 1 [Homo sapiens]
Length = 356
Score = 104 bits (259), Expect = 1e-22
Identities = 70/224 (31%), Positives = 114/224 (50%), Gaps = 28/224 (12%)
Query: 22 WVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLY--- 78
WV+KYRP +L L H++ + ++ + PHLL+YGP G GK + I+ ++LY
Sbjct: 4 WVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVG 63
Query: 79 ----------------KDKEFGSMV----LELNASDDRGID--IIRGPILSFASTR---T 113
K E ++ LE+N SD D +I+ + + A ++ T
Sbjct: 64 VEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLET 123
Query: 114 IFKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFR 173
++ FK+V+L E D +T+DAQ+ALRR +EK+ R L CN SK+IP ++SRC R
Sbjct: 124 NSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVR 183
Query: 174 FGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRAL 217
+ E + L V ++E +++ L S ++R+AL
Sbjct: 184 VPAPSIEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKAL 227
>gi|32528306 replication factor C large subunit [Homo sapiens]
Length = 1147
Score = 61.2 bits (147), Expect = 1e-09
Identities = 69/288 (23%), Positives = 113/288 (39%), Gaps = 52/288 (18%)
Query: 2 ETSALKQQEQPAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQKFI----------NED 51
++ A + + K+ NL WV+KY+P +L +I Q S K + +ED
Sbjct: 566 DSKARNLADDSSENKVENLLWVDKYKPTSLKTIIGQQGDQSCANKLLRWLRNWQKSSSED 625
Query: 52 R----------------LPHLLLYGPPGTGKTSTI-LACAKQLYKDKEFGSMVLELNASD 94
+ LL GPPG GKT+T L C +E G +ELNASD
Sbjct: 626 KKHAKFGKFSGKDDGSSFKAALLSGPPGVGKTTTASLVC-------QELGYSYVELNASD 678
Query: 95 DRGIDIIRGPILSFASTRTIFKKGF------------KLVILDEADAMTQDAQNALRRVI 142
R ++ + + +I KGF +I+DE D M + + +
Sbjct: 679 TRSKSSLKAIVAESLNNTSI--KGFYSNGAASSVSTKHALIMDEVDGMAGNEDRGGIQEL 736
Query: 143 EKFTENTRFCLICNYLSKIIPALQS---RCTRFRFGPLTPELMVPRLEHVVEEEKVDISE 199
++T+ +IC + P ++S C RF E + + + +E + I
Sbjct: 737 IGLIKHTKIPIICMCNDRNHPKIRSLVHYCFDLRFQRPRVEQIKGAMMSIAFKEGLKIPP 796
Query: 200 DGMKALVTLSSGDMRRALNILQSTNMAFGKVTEETVYTCTGHPLKSDI 247
M ++ ++ D+R+ L+ L S A K H K DI
Sbjct: 797 PAMNEIILGANQDIRQVLHNL-SMWCARSKALTYDQAKADSHRAKKDI 843
>gi|19718796 RAD17 homolog isoform 1 [Homo sapiens]
Length = 670
Score = 53.9 bits (128), Expect = 2e-07
Identities = 55/254 (21%), Positives = 105/254 (41%), Gaps = 51/254 (20%)
Query: 19 NLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPH--------LLLYGPPGTGKTSTI 70
N PWV+KY+P+T ++L H+ + ++ ++ L LL+ GPPG GKT+T+
Sbjct: 77 NEPWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTL 136
Query: 71 LACAKQ--LYKDKEFGSMVLELNASDDRGIDIIRGP--ILSFASTRTIFKKGF------- 119
+K+ + + ++ + D +G+ + + S +FK+
Sbjct: 137 KILSKEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYN 196
Query: 120 -------------KLVILDEADAMTQDAQNALRRVIEKFTENTRFCLIC---------NY 157
K++++++ + L V+ K+ R LI N
Sbjct: 197 KLQMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFIISDSLSGDNN 256
Query: 158 LSKIIP-ALQSRC--TRFRFGPLTPELMVPRLEHVVEEE------KVDI-SEDGMKALVT 207
+ P +Q C + F P+ P +M+ L +V E K+ + + ++ L
Sbjct: 257 QRLLFPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQ 316
Query: 208 LSSGDMRRALNILQ 221
SGD+R A+N LQ
Sbjct: 317 GCSGDIRSAINSLQ 330
>gi|19718794 RAD17 homolog isoform 1 [Homo sapiens]
Length = 670
Score = 53.9 bits (128), Expect = 2e-07
Identities = 55/254 (21%), Positives = 105/254 (41%), Gaps = 51/254 (20%)
Query: 19 NLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPH--------LLLYGPPGTGKTSTI 70
N PWV+KY+P+T ++L H+ + ++ ++ L LL+ GPPG GKT+T+
Sbjct: 77 NEPWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTL 136
Query: 71 LACAKQ--LYKDKEFGSMVLELNASDDRGIDIIRGP--ILSFASTRTIFKKGF------- 119
+K+ + + ++ + D +G+ + + S +FK+
Sbjct: 137 KILSKEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYN 196
Query: 120 -------------KLVILDEADAMTQDAQNALRRVIEKFTENTRFCLIC---------NY 157
K++++++ + L V+ K+ R LI N
Sbjct: 197 KLQMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFIISDSLSGDNN 256
Query: 158 LSKIIP-ALQSRC--TRFRFGPLTPELMVPRLEHVVEEE------KVDI-SEDGMKALVT 207
+ P +Q C + F P+ P +M+ L +V E K+ + + ++ L
Sbjct: 257 QRLLFPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQ 316
Query: 208 LSSGDMRRALNILQ 221
SGD+R A+N LQ
Sbjct: 317 GCSGDIRSAINSLQ 330
>gi|19718792 RAD17 homolog isoform 1 [Homo sapiens]
Length = 670
Score = 53.9 bits (128), Expect = 2e-07
Identities = 55/254 (21%), Positives = 105/254 (41%), Gaps = 51/254 (20%)
Query: 19 NLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPH--------LLLYGPPGTGKTSTI 70
N PWV+KY+P+T ++L H+ + ++ ++ L LL+ GPPG GKT+T+
Sbjct: 77 NEPWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTL 136
Query: 71 LACAKQ--LYKDKEFGSMVLELNASDDRGIDIIRGP--ILSFASTRTIFKKGF------- 119
+K+ + + ++ + D +G+ + + S +FK+
Sbjct: 137 KILSKEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYN 196
Query: 120 -------------KLVILDEADAMTQDAQNALRRVIEKFTENTRFCLIC---------NY 157
K++++++ + L V+ K+ R LI N
Sbjct: 197 KLQMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFIISDSLSGDNN 256
Query: 158 LSKIIP-ALQSRC--TRFRFGPLTPELMVPRLEHVVEEE------KVDI-SEDGMKALVT 207
+ P +Q C + F P+ P +M+ L +V E K+ + + ++ L
Sbjct: 257 QRLLFPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQ 316
Query: 208 LSSGDMRRALNILQ 221
SGD+R A+N LQ
Sbjct: 317 GCSGDIRSAINSLQ 330
>gi|19718784 RAD17 homolog isoform 1 [Homo sapiens]
Length = 670
Score = 53.9 bits (128), Expect = 2e-07
Identities = 55/254 (21%), Positives = 105/254 (41%), Gaps = 51/254 (20%)
Query: 19 NLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPH--------LLLYGPPGTGKTSTI 70
N PWV+KY+P+T ++L H+ + ++ ++ L LL+ GPPG GKT+T+
Sbjct: 77 NEPWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTL 136
Query: 71 LACAKQ--LYKDKEFGSMVLELNASDDRGIDIIRGP--ILSFASTRTIFKKGF------- 119
+K+ + + ++ + D +G+ + + S +FK+
Sbjct: 137 KILSKEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYN 196
Query: 120 -------------KLVILDEADAMTQDAQNALRRVIEKFTENTRFCLIC---------NY 157
K++++++ + L V+ K+ R LI N
Sbjct: 197 KLQMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFIISDSLSGDNN 256
Query: 158 LSKIIP-ALQSRC--TRFRFGPLTPELMVPRLEHVVEEE------KVDI-SEDGMKALVT 207
+ P +Q C + F P+ P +M+ L +V E K+ + + ++ L
Sbjct: 257 QRLLFPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQ 316
Query: 208 LSSGDMRRALNILQ 221
SGD+R A+N LQ
Sbjct: 317 GCSGDIRSAINSLQ 330
>gi|4506383 RAD17 homolog isoform 1 [Homo sapiens]
Length = 670
Score = 53.9 bits (128), Expect = 2e-07
Identities = 55/254 (21%), Positives = 105/254 (41%), Gaps = 51/254 (20%)
Query: 19 NLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPH--------LLLYGPPGTGKTSTI 70
N PWV+KY+P+T ++L H+ + ++ ++ L LL+ GPPG GKT+T+
Sbjct: 77 NEPWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTL 136
Query: 71 LACAKQ--LYKDKEFGSMVLELNASDDRGIDIIRGP--ILSFASTRTIFKKGF------- 119
+K+ + + ++ + D +G+ + + S +FK+
Sbjct: 137 KILSKEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYN 196
Query: 120 -------------KLVILDEADAMTQDAQNALRRVIEKFTENTRFCLIC---------NY 157
K++++++ + L V+ K+ R LI N
Sbjct: 197 KLQMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFIISDSLSGDNN 256
Query: 158 LSKIIP-ALQSRC--TRFRFGPLTPELMVPRLEHVVEEE------KVDI-SEDGMKALVT 207
+ P +Q C + F P+ P +M+ L +V E K+ + + ++ L
Sbjct: 257 QRLLFPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQ 316
Query: 208 LSSGDMRRALNILQ 221
SGD+R A+N LQ
Sbjct: 317 GCSGDIRSAINSLQ 330
>gi|19718786 RAD17 homolog isoform 2 [Homo sapiens]
Length = 681
Score = 53.9 bits (128), Expect = 2e-07
Identities = 55/254 (21%), Positives = 105/254 (41%), Gaps = 51/254 (20%)
Query: 19 NLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPH--------LLLYGPPGTGKTSTI 70
N PWV+KY+P+T ++L H+ + ++ ++ L LL+ GPPG GKT+T+
Sbjct: 88 NEPWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQGGSILLITGPPGCGKTTTL 147
Query: 71 LACAKQ--LYKDKEFGSMVLELNASDDRGIDIIRGP--ILSFASTRTIFKKGF------- 119
+K+ + + ++ + D +G+ + + S +FK+
Sbjct: 148 KILSKEHGIQVQEWINPVLPDFQKDDFKGMFNTESSFHMFPYQSQIAVFKEFLLRATKYN 207
Query: 120 -------------KLVILDEADAMTQDAQNALRRVIEKFTENTRFCLIC---------NY 157
K++++++ + L V+ K+ R LI N
Sbjct: 208 KLQMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRCPLIFIISDSLSGDNN 267
Query: 158 LSKIIP-ALQSRC--TRFRFGPLTPELMVPRLEHVVEEE------KVDI-SEDGMKALVT 207
+ P +Q C + F P+ P +M+ L +V E K+ + + ++ L
Sbjct: 268 QRLLFPKEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLELLCQ 327
Query: 208 LSSGDMRRALNILQ 221
SGD+R A+N LQ
Sbjct: 328 GCSGDIRSAINSLQ 341
>gi|27501458 CTF18, chromosome transmission fidelity factor 18
homolog [Homo sapiens]
Length = 975
Score = 51.2 bits (121), Expect = 1e-06
Identities = 45/193 (23%), Positives = 74/193 (38%), Gaps = 34/193 (17%)
Query: 57 LLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFK 116
LL GPPG GKT+ A+ G V+E+NASDDR ++ R I + ++
Sbjct: 371 LLCGPPGLGKTTLAHVIARHA------GYSVVEMNASDDRSPEVFRTRIEAATQMESVLG 424
Query: 117 KGFK--LVILDEADAMTQDAQNALRRVIEK--------------------------FTEN 148
G K +++DE D A N L ++ +
Sbjct: 425 AGGKPNCLVIDEIDGAPVAAINVLLSILNRKGPQEVGPQGPAVPSGGGRRRRAEGGLLMR 484
Query: 149 TRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTL 208
C+ + + + L+ + F P P +V RL+ V + + + AL
Sbjct: 485 PIICICNDQFAPSLRQLKQQAFLLHFPPTLPSRLVQRLQEVSLRQGMRADPGVLAALCEK 544
Query: 209 SSGDMRRALNILQ 221
+ D+R +N LQ
Sbjct: 545 TDNDIRACINTLQ 557
>gi|18426902 Werner helicase interacting protein isoform 1 [Homo
sapiens]
Length = 665
Score = 50.8 bits (120), Expect = 2e-06
Identities = 60/245 (24%), Positives = 98/245 (40%), Gaps = 36/245 (14%)
Query: 13 AATKIRNL----PWVEKYRPQTLNDLISHQDIL---STIQKFINEDRLPHLLLYGPPGTG 65
AA +IR + P + RP TL D + + ++ + + +P L+L+GPPG G
Sbjct: 214 AAEEIRQMLQGKPLADTMRPDTLQDYFGQSKAVGQDTLLRSLLETNEIPSLILWGPPGCG 273
Query: 66 KTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILD 125
KT+ A K+ + L+A++ + D +R I + ++ FK+ ++ +D
Sbjct: 274 KTTLAHIIAS---NSKKHSIRFVTLSATNAKTND-VRDVIKQAQNEKSFFKRK-TILFID 328
Query: 126 EADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPR 185
E + Q+ +E T N ++ AL SRC L E MV
Sbjct: 329 EIHRFNKSQQDTFLPHVECGTITLIGATTENPSFQVNAALLSRCRVIVLEKLPVEAMVTI 388
Query: 186 LE--------HVVE----------------EEKVDISEDGMKALVTLSSGDMRRALNILQ 221
L HV++ E + I + + L LS GD R LN LQ
Sbjct: 389 LMRAINSLGIHVLDSSRPTDPLSHSSNSSSEPAMFIEDKAVDTLAYLSDGDARAGLNGLQ 448
Query: 222 STNMA 226
+A
Sbjct: 449 LAVLA 453
>gi|18426904 Werner helicase interacting protein isoform 2 [Homo
sapiens]
Length = 640
Score = 45.4 bits (106), Expect = 7e-05
Identities = 56/229 (24%), Positives = 96/229 (41%), Gaps = 29/229 (12%)
Query: 13 AATKIRNL----PWVEKYRPQTLNDLISHQDIL---STIQKFINEDRLPHLLLYGPPGTG 65
AA +IR + P + RP TL D + + ++ + + +P L+L+GPPG G
Sbjct: 214 AAEEIRQMLQGKPLADTMRPDTLQDYFGQSKAVGQDTLLRSLLETNEIPSLILWGPPGCG 273
Query: 66 KTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILD 125
KT+ A K+ + L+A++ + D +R I + ++ FK+ ++ +D
Sbjct: 274 KTTLAHIIAS---NSKKHSIRFVTLSATNAKTND-VRDVIKQAQNEKSFFKRK-TILFID 328
Query: 126 EADAMTQDAQ-NA--LRR----VIEKFTENTRFCLICNYLSKI-IPALQSRCTRFRFGPL 177
E + Q NA L R V+EK ++ ++ + I L S
Sbjct: 329 EIHRFNKSQQVNAALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHVLDSS--------- 379
Query: 178 TPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMA 226
P + + E + I + + L LS GD R LN LQ +A
Sbjct: 380 RPTDPLSHSSNSSSEPAMFIEDKAVDTLAYLSDGDARAGLNGLQLAVLA 428
>gi|26080431 ATPase family, AAA domain containing 5 [Homo sapiens]
Length = 1844
Score = 40.0 bits (92), Expect = 0.003
Identities = 32/137 (23%), Positives = 54/137 (39%), Gaps = 46/137 (33%)
Query: 22 WVEKYRPQTLNDLISHQDILSTIQKFIN-------------------------------- 49
W EKY+PQT ++LI ++ + + ++
Sbjct: 1054 WTEKYQPQTASELIGNELAIKKLHSWLKDWKRRAELEERQNLKGKRDEKHEDFSGGIDFK 1113
Query: 50 -------EDRLPH-LLLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDII 101
E RL + +L+ GP G GKT+ + ACA++L G + E+NAS R I
Sbjct: 1114 GSSDDEEESRLCNTVLITGPTGVGKTAAVYACAQEL------GFKIFEVNASSQRSGRQI 1167
Query: 102 RGPILSFASTRTIFKKG 118
+ + + K+G
Sbjct: 1168 LSQLKEATQSHQVDKQG 1184
>gi|4502703 cell division cycle 6 protein [Homo sapiens]
Length = 560
Score = 37.4 bits (85), Expect = 0.019
Identities = 55/219 (25%), Positives = 91/219 (41%), Gaps = 44/219 (20%)
Query: 41 LSTIQKFINED----RLPHLLLYGPPGTGKTSTILACAKQLYKD-KEFGSMVL------- 88
+ I+ F+ E + L L G PGTGKT+ + + L K+ K F +++L
Sbjct: 179 MDVIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKKELKGFKTIMLNCMSLRT 238
Query: 89 -------------ELNASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQ 135
+ S G D++R T K +++LDE D + Q
Sbjct: 239 AQAVFPAIAQEICQEEVSRPAGKDMMR----KLEKHMTAEKGPMIVLVLDEMDQLDSKGQ 294
Query: 136 NALRRVIE-KFTENTRFCLI-----CNYLSKIIPALQSR--C--TRFRFGPLTPELMV-- 183
+ L + E + N+ LI + +I+P LQ+R C F P T +V
Sbjct: 295 DVLYTLFEWPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTI 354
Query: 184 --PRLEHVVEEEKVDISEDGMKA-LVTLSSGDMRRALNI 219
RL V ++ +D + A V+ SGD+R+AL++
Sbjct: 355 LQDRLNQVSRDQVLDNAAVQFCARKVSAVSGDVRKALDV 393
>gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens]
Length = 439
Score = 37.0 bits (84), Expect = 0.025
Identities = 26/77 (33%), Positives = 41/77 (53%), Gaps = 10/77 (12%)
Query: 56 LLLYGPPGTGKTSTILACAKQLYKD--KEFGSMVLELNASDDRGIDIIRGPILSFASTRT 113
+L+YGPPGTGKT ACA Q K G ++++ D G ++R +FA +
Sbjct: 223 VLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGD--GAKLVRD---AFALAK- 276
Query: 114 IFKKGFKLVILDEADAM 130
+K ++ +DE DA+
Sbjct: 277 --EKAPSIIFIDELDAI 291
>gi|194018490 ATPase family, AAA domain containing 3C [Homo sapiens]
Length = 411
Score = 37.0 bits (84), Expect = 0.025
Identities = 32/99 (32%), Positives = 48/99 (48%), Gaps = 12/99 (12%)
Query: 55 HLLLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTI 114
H+LLYGPPGTGK T+ A L+ ++ M A R + +A+T
Sbjct: 172 HILLYGPPGTGK--TLFAKKLALHSGMDYAIMTGGDVAPMGREGVTAMHKLFDWANTS-- 227
Query: 115 FKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCL 153
++G L+ +DEADA + +R EK +E+ R L
Sbjct: 228 -RRGL-LLFVDEADAFLR------KRATEKISEDLRATL 258
>gi|119964730 BCS1-like [Homo sapiens]
Length = 419
Score = 35.4 bits (80), Expect = 0.074
Identities = 38/119 (31%), Positives = 58/119 (48%), Gaps = 32/119 (26%)
Query: 27 RPQTLNDLISHQD----ILSTIQKFINEDR------LPH---LLLYGPPGTGKTSTILAC 73
R + LN ++ Q I+ +Q+FI+ + +P+ LLYGPPG GK+S I A
Sbjct: 184 RRRPLNSVVLQQGLADRIVRDVQEFIDNPKWYTDRGIPYRRGYLLYGPPGCGKSSFITAL 243
Query: 74 AKQLYKDKEFGSMVLEL---NASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADA 129
A +L E +L L + SDDR +LS A ++ LV+L++ DA
Sbjct: 244 AGEL----EHSICLLSLTDSSLSDDR-----LNHLLSVAPQQS-------LVLLEDVDA 286
>gi|4757852 BCS1-like [Homo sapiens]
Length = 419
Score = 35.4 bits (80), Expect = 0.074
Identities = 38/119 (31%), Positives = 58/119 (48%), Gaps = 32/119 (26%)
Query: 27 RPQTLNDLISHQD----ILSTIQKFINEDR------LPH---LLLYGPPGTGKTSTILAC 73
R + LN ++ Q I+ +Q+FI+ + +P+ LLYGPPG GK+S I A
Sbjct: 184 RRRPLNSVVLQQGLADRIVRDVQEFIDNPKWYTDRGIPYRRGYLLYGPPGCGKSSFITAL 243
Query: 74 AKQLYKDKEFGSMVLEL---NASDDRGIDIIRGPILSFASTRTIFKKGFKLVILDEADA 129
A +L E +L L + SDDR +LS A ++ LV+L++ DA
Sbjct: 244 AGEL----EHSICLLSLTDSSLSDDR-----LNHLLSVAPQQS-------LVLLEDVDA 286
>gi|75677353 AAA-ATPase TOB3 [Homo sapiens]
Length = 648
Score = 35.0 bits (79), Expect = 0.096
Identities = 30/96 (31%), Positives = 45/96 (46%), Gaps = 11/96 (11%)
Query: 55 HLLLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSFASTRTI 114
H+LLYGPPGTGK T+ A L+ ++ M A R + +A+T
Sbjct: 347 HILLYGPPGTGK--TLFAKKLALHSGMDYAIMTGGDVAPMGREGVTAMHKLFDWANTS-- 402
Query: 115 FKKGFKLVILDEADAM-----TQDAQNALRRVIEKF 145
++G L+ +DEADA T++ LR + F
Sbjct: 403 -RRGL-LLFMDEADAFLRKRATEEISKDLRATLNAF 436
>gi|21396489 mitochondrial lon peptidase 1 [Homo sapiens]
Length = 959
Score = 34.3 bits (77), Expect = 0.16
Identities = 51/214 (23%), Positives = 89/214 (41%), Gaps = 38/214 (17%)
Query: 17 IRNLPWVEKYRPQTLN----------DLISHQDILSTIQKFINEDRLPH------LLLYG 60
+ ++PW KY + L+ D +D+ I +FI +L L YG
Sbjct: 465 LTSIPW-GKYSNENLDLARAQAVLEEDHYGMEDVKKRILEFIAVSQLRGSTQGKILCFYG 523
Query: 61 PPGTGKTSTILACAKQLYKDK---EFGSM--VLELNASDDRGIDIIRGPILSFASTRTIF 115
PPG GKTS + A+ L ++ G M V E+ + + G I+
Sbjct: 524 PPGVGKTSIARSIARALNREYFRFSVGGMTDVAEIKGHRRTYVGAMPGKIIQCLKKT--- 580
Query: 116 KKGFKLVILDEADAMTQ----DAQNALRRVIEKFTENTRFCLICNY------LSKIIPAL 165
K L+++DE D + + D +AL +++ +N F + +Y LSK++
Sbjct: 581 KTENPLILIDEVDKIGRGYQGDPSSALLELLDP-EQNANF--LDHYLDVPVDLSKVLFIC 637
Query: 166 QSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISE 199
+ T PL + + + V +EK+ I+E
Sbjct: 638 TANVTDTIPEPLRDRMEMINVSGYVAQEKLAIAE 671
>gi|31377667 peroxisomal LON protease-like [Homo sapiens]
Length = 852
Score = 33.9 bits (76), Expect = 0.21
Identities = 43/171 (25%), Positives = 77/171 (45%), Gaps = 23/171 (13%)
Query: 44 IQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKEFGSMVL--ELNASDDRG---- 97
+++ N + P L GPPG GKTS + AK L +EF + L + SD RG
Sbjct: 359 VRQLKNNLKGPILCFVGPPGVGKTSVGRSVAKTL--GREFHRIALGGVCDQSDIRGHRRT 416
Query: 98 -IDIIRGPILSFASTRTIFKKGFKLVILDEADAMTQDAQN----ALRRVIE-----KFTE 147
+ + G I++ T + F +LDE D + + Q AL V++ FT+
Sbjct: 417 YVGSMPGRIINGLKTVGVNNPVF---LLDEVDKLGKSLQGDPAAALLEVLDPEQNHNFTD 473
Query: 148 NTRFCLICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDIS 198
+ + + LS+++ + T L + + ++ +EEK++I+
Sbjct: 474 H--YLNVAFDLSQVLFIATANTTATIPAALLDRMEIIQVPGYTQEEKIEIA 522
>gi|42476028 ATPase family, AAA domain containing 3A [Homo sapiens]
Length = 634
Score = 33.9 bits (76), Expect = 0.21
Identities = 31/105 (29%), Positives = 49/105 (46%), Gaps = 12/105 (11%)
Query: 49 NEDRLPHLLLYGPPGTGKTSTILACAKQLYKDKEFGSMVLELNASDDRGIDIIRGPILSF 108
N ++L+YGPPGTGK T+ A L+ ++ M A R + +
Sbjct: 389 NRSLYRNILMYGPPGTGK--TLFAKKLALHSGMDYAIMTGGDVAPMGREGVTAMHKLFDW 446
Query: 109 ASTRTIFKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCL 153
A+T ++G L+ +DEADA + +R EK +E+ R L
Sbjct: 447 ANTS---RRGL-LLFVDEADAFLR------KRATEKISEDLRATL 481
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,602,748
Number of Sequences: 37866
Number of extensions: 470621
Number of successful extensions: 1386
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 1293
Number of HSP's gapped (non-prelim): 96
length of query: 340
length of database: 18,247,518
effective HSP length: 103
effective length of query: 237
effective length of database: 14,347,320
effective search space: 3400314840
effective search space used: 3400314840
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.