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Search of human proteins with 66346737
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|66346737 glucosidase, alpha; neutral C [Homo sapiens]
(914 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|66346737 glucosidase, alpha; neutral C [Homo sapiens] 1885 0.0
gi|38202257 neutral alpha-glucosidase AB isoform 2 [Homo sapiens] 959 0.0
gi|88900491 neutral alpha-glucosidase AB isoform 3 [Homo sapiens] 951 0.0
gi|119393895 acid alpha-glucosidase preproprotein [Homo sapiens] 333 6e-91
gi|119393893 acid alpha-glucosidase preproprotein [Homo sapiens] 333 6e-91
gi|119393891 acid alpha-glucosidase preproprotein [Homo sapiens] 333 6e-91
gi|157364974 sucrase-isomaltase [Homo sapiens] 298 2e-80
gi|221316699 maltase-glucoamylase [Homo sapiens] 282 9e-76
gi|169171979 PREDICTED: similar to sucrase-isomaltase [Homo sapi... 248 2e-65
gi|153791946 hypothetical protein LOC57462 [Homo sapiens] 83 1e-15
gi|193083163 roundabout, axon guidance receptor, homolog 2 isofo... 33 1.6
gi|61888896 roundabout, axon guidance receptor, homolog 2 isofor... 33 1.6
gi|209447073 synaptotagmin I [Homo sapiens] 32 3.5
gi|5032139 synaptotagmin I [Homo sapiens] 32 3.5
gi|209447070 synaptotagmin I [Homo sapiens] 32 3.5
gi|223972648 t-SNARE domain containing 1 [Homo sapiens] 31 4.6
gi|165377209 methyltransferase 5 domain containing 1 isoform 1 [... 31 4.6
gi|165377202 methyltransferase 5 domain containing 1 isoform 2 [... 31 4.6
gi|4503015 copine III [Homo sapiens] 30 7.9
gi|119372317 xin actin-binding repeat containing 2 isoform 1 [Ho... 30 7.9
gi|119372315 xin actin-binding repeat containing 2 isoform 2 [Ho... 30 7.9
gi|109637791 transcription factor-like nuclear regulator [Homo s... 30 7.9
>gi|66346737 glucosidase, alpha; neutral C [Homo sapiens]
Length = 914
Score = 1885 bits (4884), Expect = 0.0
Identities = 914/914 (100%), Positives = 914/914 (100%)
Query: 1 MEAAVKEEISLEDEAVDKNIFRDCNKIAFYRRQKQWLSKKSTYQALLDSVTTDEDSTRFQ 60
MEAAVKEEISLEDEAVDKNIFRDCNKIAFYRRQKQWLSKKSTYQALLDSVTTDEDSTRFQ
Sbjct: 1 MEAAVKEEISLEDEAVDKNIFRDCNKIAFYRRQKQWLSKKSTYQALLDSVTTDEDSTRFQ 60
Query: 61 IINEASKVPLLAEIYGIEGNIFRLKINEETPLKPRFEVPDVLTSKPSTVRLISCSGDTGS 120
IINEASKVPLLAEIYGIEGNIFRLKINEETPLKPRFEVPDVLTSKPSTVRLISCSGDTGS
Sbjct: 61 IINEASKVPLLAEIYGIEGNIFRLKINEETPLKPRFEVPDVLTSKPSTVRLISCSGDTGS 120
Query: 121 LILADGKGDLKCHITANPFKVDLVSEEEVVISINSLGQLYFEHLQILHKQRAAKENEEET 180
LILADGKGDLKCHITANPFKVDLVSEEEVVISINSLGQLYFEHLQILHKQRAAKENEEET
Sbjct: 121 LILADGKGDLKCHITANPFKVDLVSEEEVVISINSLGQLYFEHLQILHKQRAAKENEEET 180
Query: 181 SVDTSQENQEDLGLWEEKFGKFVDIKANGPSSIGLDFSLHGFEHLYGIPQHAESHQLKNT 240
SVDTSQENQEDLGLWEEKFGKFVDIKANGPSSIGLDFSLHGFEHLYGIPQHAESHQLKNT
Sbjct: 181 SVDTSQENQEDLGLWEEKFGKFVDIKANGPSSIGLDFSLHGFEHLYGIPQHAESHQLKNT 240
Query: 241 GDGDAYRLYNLDVYGYQIYDKMGIYGSVPYLLAHKLGRTIGIFWLNASETLVEINTEPAV 300
GDGDAYRLYNLDVYGYQIYDKMGIYGSVPYLLAHKLGRTIGIFWLNASETLVEINTEPAV
Sbjct: 241 GDGDAYRLYNLDVYGYQIYDKMGIYGSVPYLLAHKLGRTIGIFWLNASETLVEINTEPAV 300
Query: 301 EYTLTQMGPVAAKQKVRSRTHVHWMSESGIIDVFLLTGPTPSDVFKQYSHLTGTQAMPPL 360
EYTLTQMGPVAAKQKVRSRTHVHWMSESGIIDVFLLTGPTPSDVFKQYSHLTGTQAMPPL
Sbjct: 301 EYTLTQMGPVAAKQKVRSRTHVHWMSESGIIDVFLLTGPTPSDVFKQYSHLTGTQAMPPL 360
Query: 361 FSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDAMWLDIEHTEGKRYFTWDKNRFPNPKR 420
FSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDAMWLDIEHTEGKRYFTWDKNRFPNPKR
Sbjct: 361 FSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDAMWLDIEHTEGKRYFTWDKNRFPNPKR 420
Query: 421 MQELLRSKKRKLVVISDPHIKIDPDYSVYVKAKDQGFFVKNQEGEDFEGVCWPGLSSYLD 480
MQELLRSKKRKLVVISDPHIKIDPDYSVYVKAKDQGFFVKNQEGEDFEGVCWPGLSSYLD
Sbjct: 421 MQELLRSKKRKLVVISDPHIKIDPDYSVYVKAKDQGFFVKNQEGEDFEGVCWPGLSSYLD 480
Query: 481 FTNPKVREWYSSLFAFPVYQGSTDILFLWNDMNEPSVFRGPEQTMQKNAIHHGNWEHREL 540
FTNPKVREWYSSLFAFPVYQGSTDILFLWNDMNEPSVFRGPEQTMQKNAIHHGNWEHREL
Sbjct: 481 FTNPKVREWYSSLFAFPVYQGSTDILFLWNDMNEPSVFRGPEQTMQKNAIHHGNWEHREL 540
Query: 541 HNIYGFYHQMATAEGLIKRSKGKERPFVLTRSFFAGSQKYGAVWTGDNTAEWSNLKISIP 600
HNIYGFYHQMATAEGLIKRSKGKERPFVLTRSFFAGSQKYGAVWTGDNTAEWSNLKISIP
Sbjct: 541 HNIYGFYHQMATAEGLIKRSKGKERPFVLTRSFFAGSQKYGAVWTGDNTAEWSNLKISIP 600
Query: 601 MLLTLSITGISFCGADIGGFIGNPETELLVRWYQAGAYQPFFRGHATMNTKRREPWLFGE 660
MLLTLSITGISFCGADIGGFIGNPETELLVRWYQAGAYQPFFRGHATMNTKRREPWLFGE
Sbjct: 601 MLLTLSITGISFCGADIGGFIGNPETELLVRWYQAGAYQPFFRGHATMNTKRREPWLFGE 660
Query: 661 EHTRLIREAIRERYGLLPYWYSLFYHAHVASQPVMRPLWVEFPDELKTFDMEDEYMLGSA 720
EHTRLIREAIRERYGLLPYWYSLFYHAHVASQPVMRPLWVEFPDELKTFDMEDEYMLGSA
Sbjct: 661 EHTRLIREAIRERYGLLPYWYSLFYHAHVASQPVMRPLWVEFPDELKTFDMEDEYMLGSA 720
Query: 721 LLVHPVTEPKATTVDVFLPGSNEVWYDYKTFAHWEGGCTVKIPVALDTIPVFQRGGSVIP 780
LLVHPVTEPKATTVDVFLPGSNEVWYDYKTFAHWEGGCTVKIPVALDTIPVFQRGGSVIP
Sbjct: 721 LLVHPVTEPKATTVDVFLPGSNEVWYDYKTFAHWEGGCTVKIPVALDTIPVFQRGGSVIP 780
Query: 781 IKTTVGKSTGWMTESSYGLRVALSTKGSSVGELYLDDGHSFQYLHQKQFLHRKFSFCSSV 840
IKTTVGKSTGWMTESSYGLRVALSTKGSSVGELYLDDGHSFQYLHQKQFLHRKFSFCSSV
Sbjct: 781 IKTTVGKSTGWMTESSYGLRVALSTKGSSVGELYLDDGHSFQYLHQKQFLHRKFSFCSSV 840
Query: 841 LINSFADQRGHYPSKCVVEKILVLGFRKEPSSVTTHSSDGKDQPVAFTYCAKTSILSLEK 900
LINSFADQRGHYPSKCVVEKILVLGFRKEPSSVTTHSSDGKDQPVAFTYCAKTSILSLEK
Sbjct: 841 LINSFADQRGHYPSKCVVEKILVLGFRKEPSSVTTHSSDGKDQPVAFTYCAKTSILSLEK 900
Query: 901 LSLNIATDWEVRII 914
LSLNIATDWEVRII
Sbjct: 901 LSLNIATDWEVRII 914
>gi|38202257 neutral alpha-glucosidase AB isoform 2 [Homo sapiens]
Length = 944
Score = 959 bits (2480), Expect = 0.0
Identities = 458/913 (50%), Positives = 633/913 (69%), Gaps = 15/913 (1%)
Query: 15 AVDKNIFRDCNKIAFYRRQKQWLSKKSTYQALLDSVTTDEDSTRFQIINEASKVPLLAEI 74
AVD++ F+ C + +F +RQ+ S Y+ALLDS+ DS +I+E +KV L+ E+
Sbjct: 32 AVDRSNFKTCEESSFCKRQRSIRPGLSPYRALLDSLQLGPDSLTVHLIHEVTKVLLVLEL 91
Query: 75 YGIEGNIFRLKINEETPLKPRFEVPDVLTSKPSTVRLISCSGDTGSLILADGKGDLKCHI 134
G++ N+ R +I+E P +PR+ VPDVL + P RL D S+ L +G K +
Sbjct: 92 QGLQKNMTRFRIDELEPRRPRYRVPDVLVADPPIARLSVSGRDENSVELTMAEGPYKIIL 151
Query: 135 TANPFKVDLVSEEEVVISINSLGQLYFEHLQILHKQRAAKE-------NEEETSVDTSQE 187
TA PF++DL+ + +++S+N+ G L FEH + + +K+ EET D +
Sbjct: 152 TARPFRLDLLEDRSLLLSVNARGLLEFEHQRAPRVSQGSKDPAEGDGAQPEETPRDGDKP 211
Query: 188 NQ-------EDLGLWEEKFGKFVDIKANGPSSIGLDFSLHGFEHLYGIPQHAESHQLKNT 240
+ ++ G WEE F D K GP S+GLDFSL G EH+YGIP+HA++ +LK T
Sbjct: 212 EETQGKAEKDEPGAWEETFKTHSDSKPYGPMSVGLDFSLPGMEHVYGIPEHADNLRLKVT 271
Query: 241 GDGDAYRLYNLDVYGYQIYDKMGIYGSVPYLLAHKLGRTIGIFWLNASETLVEINTEPAV 300
G+ YRLYNLDV+ Y++Y+ M +YGSVP LLAH R +GIFWLNA+ET V+I++ A
Sbjct: 272 EGGEPYRLYNLDVFQYELYNPMALYGSVPVLLAHNPHRDLGIFWLNAAETWVDISSNTAG 331
Query: 301 EYTLTQMGPVAAKQKVRSRTHVHWMSESGIIDVFLLTGPTPSDVFKQYSHLTGTQAMPPL 360
+ +M +T V WMSE+GIIDVFLL GP+ SDVF+QY+ LTGTQA+PPL
Sbjct: 332 KTLFGKMMDYLQGSGETPQTDVRWMSETGIIDVFLLLGPSISDVFRQYASLTGTQALPPL 391
Query: 361 FSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDAMWLDIEHTEGKRYFTWDKNRFPNPKR 420
FSLGYHQ RWNY DE DV VD GFD+H++P D +WLDIEH +GKRYFTWD +RFP P+
Sbjct: 392 FSLGYHQSRWNYRDEADVLEVDQGFDDHNLPCDVIWLDIEHADGKRYFTWDPSRFPQPRT 451
Query: 421 MQELLRSKKRKLVVISDPHIKIDPDYSVYVKAKDQGFFVKNQEGEDFEGVCWPGLSSYLD 480
M E L SK+RKLV I DPHIK+D Y V+ + ++ G +VK ++G D+EG CWPG + Y D
Sbjct: 452 MLERLASKRRKLVAIVDPHIKVDSGYRVHEELRNLGLYVKTRDGSDYEGWCWPGSAGYPD 511
Query: 481 FTNPKVREWYSSLFAFPVYQGSTDILFLWNDMNEPSVFRGPEQTMQKNAIHHGNWEHREL 540
FTNP +R W++++F++ Y+GS LF+WNDMNEPSVF GPE TM K+A H+G WEHR++
Sbjct: 512 FTNPTMRAWWANMFSYDNYEGSAPNLFVWNDMNEPSVFNGPEVTMLKDAQHYGGWEHRDV 571
Query: 541 HNIYGFYHQMATAEGLIKRSKGKERPFVLTRSFFAGSQKYGAVWTGDNTAEWSNLKISIP 600
HNIYG Y MATA+GL +RS G ERPFVL R+FFAGSQ++GAVWTGDNTAEW +LKISIP
Sbjct: 572 HNIYGLYVHMATADGLRQRSGGMERPFVLARAFFAGSQRFGAVWTGDNTAEWDHLKISIP 631
Query: 601 MLLTLSITGISFCGADIGGFIGNPETELLVRWYQAGAYQPFFRGHATMNTKRREPWLFGE 660
M L+L + G+SFCGAD+GGF NPE ELLVRWYQ GAYQPFFR HA ++T RREPWL
Sbjct: 632 MCLSLGLVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLPS 691
Query: 661 EHTRLIREAIRERYGLLPYWYSLFYHAHVASQPVMRPLWVEFPDELKTFDMEDEYMLGSA 720
+H +IR+A+ +RY LLP+WY+L Y AH PVMRPLWV++P ++ TF+++D+Y+LG A
Sbjct: 692 QHNDIIRDALGQRYSLLPFWYTLLYQAHREGIPVMRPLWVQYPQDVTTFNIDDQYLLGDA 751
Query: 721 LLVHPVTEPKATTVDVFLPGSNEVWYDYKTFAHWEGGCTVKIPVALDTIPVFQRGGSVIP 780
LLVHPV++ A V V+LPG EVWYD +++ G T+ +PV L +IPVFQRGG+++P
Sbjct: 752 LLVHPVSDSGAHGVQVYLPGQGEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVP 811
Query: 781 IKTTVGKSTGWMTESSYGLRVALSTKGSSVGELYLDDGHSFQYLHQKQFLHRKFSFCSSV 840
V +S+ M + L VALS +G++ GEL+LDDGH+F Y +++FL R+FSF +
Sbjct: 812 RWMRVRRSSECMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRQEFLLRRFSFSGNT 871
Query: 841 LINSFADQRGHYPSKCVVEKILVLGFRKEPSSVTTHSSDGKDQPVAFTYCAKTSILSLEK 900
L++S AD GH+ + +E+++++G K P++V + + ++F + +TS+L L K
Sbjct: 872 LVSSSADPEGHFETPIWIERVVIIGAGK-PAAVVLQTKGSPESRLSFQHDPETSVLVLRK 930
Query: 901 LSLNIATDWEVRI 913
+N+A+DW + +
Sbjct: 931 PGINVASDWSIHL 943
>gi|88900491 neutral alpha-glucosidase AB isoform 3 [Homo sapiens]
Length = 966
Score = 951 bits (2458), Expect = 0.0
Identities = 459/935 (49%), Positives = 636/935 (68%), Gaps = 37/935 (3%)
Query: 15 AVDKNIFRDCNKIAFYRRQKQWLSKKSTYQALLDSVTTDEDSTRFQIINEASKVPLLAEI 74
AVD++ F+ C + +F +RQ+ S Y+ALLDS+ DS +I+E +KV L+ E+
Sbjct: 32 AVDRSNFKTCEESSFCKRQRSIRPGLSPYRALLDSLQLGPDSLTVHLIHEVTKVLLVLEL 91
Query: 75 YGIEGNIFRLKINEETPLKPRFEVPDVLTSKPSTVRLISCSGDTGSLILADGKGDLKCHI 134
G++ N+ R +I+E P +PR+ VPDVL + P RL D S+ L +G K +
Sbjct: 92 QGLQKNMTRFRIDELEPRRPRYRVPDVLVADPPIARLSVSGRDENSVELTMAEGPYKIIL 151
Query: 135 TANPFKVDLVSEEEVVISINSLGQLYFEH----------------------LQILHKQRA 172
TA PF++DL+ + +++S+N+ G L FEH ++ L ++
Sbjct: 152 TARPFRLDLLEDRSLLLSVNARGLLEFEHQRAPRVSFSDKVNLTLGSIWDKIKNLFSRQG 211
Query: 173 AKE-------NEEETSVDTSQENQ-------EDLGLWEEKFGKFVDIKANGPSSIGLDFS 218
+K+ EET D + + ++ G WEE F D K GP S+GLDFS
Sbjct: 212 SKDPAEGDGAQPEETPRDGDKPEETQGKAEKDEPGAWEETFKTHSDSKPYGPMSVGLDFS 271
Query: 219 LHGFEHLYGIPQHAESHQLKNTGDGDAYRLYNLDVYGYQIYDKMGIYGSVPYLLAHKLGR 278
L G EH+YGIP+HA++ +LK T G+ YRLYNLDV+ Y++Y+ M +YGSVP LLAH R
Sbjct: 272 LPGMEHVYGIPEHADNLRLKVTEGGEPYRLYNLDVFQYELYNPMALYGSVPVLLAHNPHR 331
Query: 279 TIGIFWLNASETLVEINTEPAVEYTLTQMGPVAAKQKVRSRTHVHWMSESGIIDVFLLTG 338
+GIFWLNA+ET V+I++ A + +M +T V WMSE+GIIDVFLL G
Sbjct: 332 DLGIFWLNAAETWVDISSNTAGKTLFGKMMDYLQGSGETPQTDVRWMSETGIIDVFLLLG 391
Query: 339 PTPSDVFKQYSHLTGTQAMPPLFSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDAMWLD 398
P+ SDVF+QY+ LTGTQA+PPLFSLGYHQ RWNY DE DV VD GFD+H++P D +WLD
Sbjct: 392 PSISDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNLPCDVIWLD 451
Query: 399 IEHTEGKRYFTWDKNRFPNPKRMQELLRSKKRKLVVISDPHIKIDPDYSVYVKAKDQGFF 458
IEH +GKRYFTWD +RFP P+ M E L SK+RKLV I DPHIK+D Y V+ + ++ G +
Sbjct: 452 IEHADGKRYFTWDPSRFPQPRTMLERLASKRRKLVAIVDPHIKVDSGYRVHEELRNLGLY 511
Query: 459 VKNQEGEDFEGVCWPGLSSYLDFTNPKVREWYSSLFAFPVYQGSTDILFLWNDMNEPSVF 518
VK ++G D+EG CWPG + Y DFTNP +R W++++F++ Y+GS LF+WNDMNEPSVF
Sbjct: 512 VKTRDGSDYEGWCWPGSAGYPDFTNPTMRAWWANMFSYDNYEGSAPNLFVWNDMNEPSVF 571
Query: 519 RGPEQTMQKNAIHHGNWEHRELHNIYGFYHQMATAEGLIKRSKGKERPFVLTRSFFAGSQ 578
GPE TM K+A H+G WEHR++HNIYG Y MATA+GL +RS G ERPFVL R+FFAGSQ
Sbjct: 572 NGPEVTMLKDAQHYGGWEHRDVHNIYGLYVHMATADGLRQRSGGMERPFVLARAFFAGSQ 631
Query: 579 KYGAVWTGDNTAEWSNLKISIPMLLTLSITGISFCGADIGGFIGNPETELLVRWYQAGAY 638
++GAVWTGDNTAEW +LKISIPM L+L + G+SFCGAD+GGF NPE ELLVRWYQ GAY
Sbjct: 632 RFGAVWTGDNTAEWDHLKISIPMCLSLGLVGLSFCGADVGGFFKNPEPELLVRWYQMGAY 691
Query: 639 QPFFRGHATMNTKRREPWLFGEEHTRLIREAIRERYGLLPYWYSLFYHAHVASQPVMRPL 698
QPFFR HA ++T RREPWL +H +IR+A+ +RY LLP+WY+L Y AH PVMRPL
Sbjct: 692 QPFFRAHAHLDTGRREPWLLPSQHNDIIRDALGQRYSLLPFWYTLLYQAHREGIPVMRPL 751
Query: 699 WVEFPDELKTFDMEDEYMLGSALLVHPVTEPKATTVDVFLPGSNEVWYDYKTFAHWEGGC 758
WV++P ++ TF+++D+Y+LG ALLVHPV++ A V V+LPG EVWYD +++ G
Sbjct: 752 WVQYPQDVTTFNIDDQYLLGDALLVHPVSDSGAHGVQVYLPGQGEVWYDIQSYQKHHGPQ 811
Query: 759 TVKIPVALDTIPVFQRGGSVIPIKTTVGKSTGWMTESSYGLRVALSTKGSSVGELYLDDG 818
T+ +PV L +IPVFQRGG+++P V +S+ M + L VALS +G++ GEL+LDDG
Sbjct: 812 TLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSECMKDDPITLFVALSPQGTAQGELFLDDG 871
Query: 819 HSFQYLHQKQFLHRKFSFCSSVLINSFADQRGHYPSKCVVEKILVLGFRKEPSSVTTHSS 878
H+F Y +++FL R+FSF + L++S AD GH+ + +E+++++G K P++V +
Sbjct: 872 HTFNYQTRQEFLLRRFSFSGNTLVSSSADPEGHFETPIWIERVVIIGAGK-PAAVVLQTK 930
Query: 879 DGKDQPVAFTYCAKTSILSLEKLSLNIATDWEVRI 913
+ ++F + +TS+L L K +N+A+DW + +
Sbjct: 931 GSPESRLSFQHDPETSVLVLRKPGINVASDWSIHL 965
>gi|119393895 acid alpha-glucosidase preproprotein [Homo sapiens]
Length = 952
Score = 333 bits (853), Expect = 6e-91
Identities = 213/682 (31%), Positives = 326/682 (47%), Gaps = 82/682 (12%)
Query: 264 IYGSVPYLLAHKLGRTI-GIFWLNASETLVEINTEPAVEYTLTQMGPVAAKQKVRSRTHV 322
+YGS P+ LA + G + G+F LN++ V + PA+
Sbjct: 291 LYGSHPFYLALEDGGSAHGVFLLNSNAMDVVLQPSPALS--------------------- 329
Query: 323 HWMSESGIIDVFLLTGPTPSDVFKQYSHLTGTQAMPPLFSLGYHQCRWNYEDEQDVKAVD 382
W S GI+DV++ GP P V +QY + G MPP + LG+H CRW Y + V
Sbjct: 330 -WRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVV 388
Query: 383 AGFDEHDIPYDAMWLDIEHTEGKRYFTWDKNRFPNPKRMQELLRSKKRKLVVISDPHIKI 442
P D W D+++ + +R FT++K+ F + M + L R+ ++I DP I
Sbjct: 389 ENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISS 448
Query: 443 DP---DYSVYVKAKDQGFFVKNQEGEDFEGVCWPGLSSYLDFTNPKVREWYSSLFAFPVY 499
Y Y + +G F+ N+ G+ G WPG +++ DFTNP W+ + A +
Sbjct: 449 SGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVA--EF 506
Query: 500 QGSTDILFLWNDMNEPSVF-RGPEQTMQKNAIHHGNW----------------------- 535
+W DMNEPS F RG E N + + +
Sbjct: 507 HDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLS 566
Query: 536 EHRELHNIYGFYHQMATAEGLIKRSKGKERPFVLTRSFFAGSQKYGAVWTGDNTAEWSNL 595
H LHN+YG +A+ L+K ++G RPFV++RS FAG +Y WTGD + W L
Sbjct: 567 THYNLHNLYGLTEAIASHRALVK-ARGT-RPFVISRSTFAGHGRYAGHWTGDVWSSWEQL 624
Query: 596 KISIPMLLTLSITGISFCGADIGGFIGNPETELLVRWYQAGAYQPFFRGHATMNTKRREP 655
S+P +L ++ G+ GAD+ GF+GN EL VRW Q GA+ PF R H ++ + +EP
Sbjct: 625 ASSVPEILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEP 684
Query: 656 WLFGEEHTRLIREAIRERYGLLPYWYSLFYHAHVASQPVMRPLWVEFPDELKTFDMEDEY 715
+ F E + +R+A+ RY LLP+ Y+LF+ AHVA + V RPL++EFP + T+ ++ +
Sbjct: 685 YSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQL 744
Query: 716 MLGSALLVHPVTEPKATTVDVFLPGSNEVWYDYKTF------------------AHWEGG 757
+ G ALL+ PV + V + P WYD +T A G
Sbjct: 745 LWGEALLITPVLQAGKAEVTGYFPLG--TWYDLQTVPVEALGSLPPPPAAPREPAIHSEG 802
Query: 758 CTVKIPVALDTIPVFQRGGSVIPIKTTVGKSTGWMTESSYGLRVALSTKGSSVGELYLDD 817
V +P LDTI V R G +IP++ G +T + L VAL+ G + GEL+ DD
Sbjct: 803 QWVTLPAPLDTINVHLRAGYIIPLQGP-GLTTTESRQQPMALAVALTKGGEARGELFWDD 861
Query: 818 GHSFQYLHQKQFLHRKFSFCSSVLINSFADQRGHYPSKCVVEKILVLGFRKEPSSVTTHS 877
G S + L + + F ++ ++N + ++K+ VLG P V ++
Sbjct: 862 GESLEVLERGAYTQVIFLARNNTIVNELVRVTSE-GAGLQLQKVTVLGVATAPQQVLSNG 920
Query: 878 SDGKDQPVA-FTYCAKTSILSL 898
PV+ FTY T +L +
Sbjct: 921 -----VPVSNFTYSPDTKVLDI 937
>gi|119393893 acid alpha-glucosidase preproprotein [Homo sapiens]
Length = 952
Score = 333 bits (853), Expect = 6e-91
Identities = 213/682 (31%), Positives = 326/682 (47%), Gaps = 82/682 (12%)
Query: 264 IYGSVPYLLAHKLGRTI-GIFWLNASETLVEINTEPAVEYTLTQMGPVAAKQKVRSRTHV 322
+YGS P+ LA + G + G+F LN++ V + PA+
Sbjct: 291 LYGSHPFYLALEDGGSAHGVFLLNSNAMDVVLQPSPALS--------------------- 329
Query: 323 HWMSESGIIDVFLLTGPTPSDVFKQYSHLTGTQAMPPLFSLGYHQCRWNYEDEQDVKAVD 382
W S GI+DV++ GP P V +QY + G MPP + LG+H CRW Y + V
Sbjct: 330 -WRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVV 388
Query: 383 AGFDEHDIPYDAMWLDIEHTEGKRYFTWDKNRFPNPKRMQELLRSKKRKLVVISDPHIKI 442
P D W D+++ + +R FT++K+ F + M + L R+ ++I DP I
Sbjct: 389 ENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISS 448
Query: 443 DP---DYSVYVKAKDQGFFVKNQEGEDFEGVCWPGLSSYLDFTNPKVREWYSSLFAFPVY 499
Y Y + +G F+ N+ G+ G WPG +++ DFTNP W+ + A +
Sbjct: 449 SGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVA--EF 506
Query: 500 QGSTDILFLWNDMNEPSVF-RGPEQTMQKNAIHHGNW----------------------- 535
+W DMNEPS F RG E N + + +
Sbjct: 507 HDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLS 566
Query: 536 EHRELHNIYGFYHQMATAEGLIKRSKGKERPFVLTRSFFAGSQKYGAVWTGDNTAEWSNL 595
H LHN+YG +A+ L+K ++G RPFV++RS FAG +Y WTGD + W L
Sbjct: 567 THYNLHNLYGLTEAIASHRALVK-ARGT-RPFVISRSTFAGHGRYAGHWTGDVWSSWEQL 624
Query: 596 KISIPMLLTLSITGISFCGADIGGFIGNPETELLVRWYQAGAYQPFFRGHATMNTKRREP 655
S+P +L ++ G+ GAD+ GF+GN EL VRW Q GA+ PF R H ++ + +EP
Sbjct: 625 ASSVPEILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEP 684
Query: 656 WLFGEEHTRLIREAIRERYGLLPYWYSLFYHAHVASQPVMRPLWVEFPDELKTFDMEDEY 715
+ F E + +R+A+ RY LLP+ Y+LF+ AHVA + V RPL++EFP + T+ ++ +
Sbjct: 685 YSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQL 744
Query: 716 MLGSALLVHPVTEPKATTVDVFLPGSNEVWYDYKTF------------------AHWEGG 757
+ G ALL+ PV + V + P WYD +T A G
Sbjct: 745 LWGEALLITPVLQAGKAEVTGYFPLG--TWYDLQTVPVEALGSLPPPPAAPREPAIHSEG 802
Query: 758 CTVKIPVALDTIPVFQRGGSVIPIKTTVGKSTGWMTESSYGLRVALSTKGSSVGELYLDD 817
V +P LDTI V R G +IP++ G +T + L VAL+ G + GEL+ DD
Sbjct: 803 QWVTLPAPLDTINVHLRAGYIIPLQGP-GLTTTESRQQPMALAVALTKGGEARGELFWDD 861
Query: 818 GHSFQYLHQKQFLHRKFSFCSSVLINSFADQRGHYPSKCVVEKILVLGFRKEPSSVTTHS 877
G S + L + + F ++ ++N + ++K+ VLG P V ++
Sbjct: 862 GESLEVLERGAYTQVIFLARNNTIVNELVRVTSE-GAGLQLQKVTVLGVATAPQQVLSNG 920
Query: 878 SDGKDQPVA-FTYCAKTSILSL 898
PV+ FTY T +L +
Sbjct: 921 -----VPVSNFTYSPDTKVLDI 937
>gi|119393891 acid alpha-glucosidase preproprotein [Homo sapiens]
Length = 952
Score = 333 bits (853), Expect = 6e-91
Identities = 213/682 (31%), Positives = 326/682 (47%), Gaps = 82/682 (12%)
Query: 264 IYGSVPYLLAHKLGRTI-GIFWLNASETLVEINTEPAVEYTLTQMGPVAAKQKVRSRTHV 322
+YGS P+ LA + G + G+F LN++ V + PA+
Sbjct: 291 LYGSHPFYLALEDGGSAHGVFLLNSNAMDVVLQPSPALS--------------------- 329
Query: 323 HWMSESGIIDVFLLTGPTPSDVFKQYSHLTGTQAMPPLFSLGYHQCRWNYEDEQDVKAVD 382
W S GI+DV++ GP P V +QY + G MPP + LG+H CRW Y + V
Sbjct: 330 -WRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVV 388
Query: 383 AGFDEHDIPYDAMWLDIEHTEGKRYFTWDKNRFPNPKRMQELLRSKKRKLVVISDPHIKI 442
P D W D+++ + +R FT++K+ F + M + L R+ ++I DP I
Sbjct: 389 ENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISS 448
Query: 443 DP---DYSVYVKAKDQGFFVKNQEGEDFEGVCWPGLSSYLDFTNPKVREWYSSLFAFPVY 499
Y Y + +G F+ N+ G+ G WPG +++ DFTNP W+ + A +
Sbjct: 449 SGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVA--EF 506
Query: 500 QGSTDILFLWNDMNEPSVF-RGPEQTMQKNAIHHGNW----------------------- 535
+W DMNEPS F RG E N + + +
Sbjct: 507 HDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLS 566
Query: 536 EHRELHNIYGFYHQMATAEGLIKRSKGKERPFVLTRSFFAGSQKYGAVWTGDNTAEWSNL 595
H LHN+YG +A+ L+K ++G RPFV++RS FAG +Y WTGD + W L
Sbjct: 567 THYNLHNLYGLTEAIASHRALVK-ARGT-RPFVISRSTFAGHGRYAGHWTGDVWSSWEQL 624
Query: 596 KISIPMLLTLSITGISFCGADIGGFIGNPETELLVRWYQAGAYQPFFRGHATMNTKRREP 655
S+P +L ++ G+ GAD+ GF+GN EL VRW Q GA+ PF R H ++ + +EP
Sbjct: 625 ASSVPEILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEP 684
Query: 656 WLFGEEHTRLIREAIRERYGLLPYWYSLFYHAHVASQPVMRPLWVEFPDELKTFDMEDEY 715
+ F E + +R+A+ RY LLP+ Y+LF+ AHVA + V RPL++EFP + T+ ++ +
Sbjct: 685 YSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQL 744
Query: 716 MLGSALLVHPVTEPKATTVDVFLPGSNEVWYDYKTF------------------AHWEGG 757
+ G ALL+ PV + V + P WYD +T A G
Sbjct: 745 LWGEALLITPVLQAGKAEVTGYFPLG--TWYDLQTVPVEALGSLPPPPAAPREPAIHSEG 802
Query: 758 CTVKIPVALDTIPVFQRGGSVIPIKTTVGKSTGWMTESSYGLRVALSTKGSSVGELYLDD 817
V +P LDTI V R G +IP++ G +T + L VAL+ G + GEL+ DD
Sbjct: 803 QWVTLPAPLDTINVHLRAGYIIPLQGP-GLTTTESRQQPMALAVALTKGGEARGELFWDD 861
Query: 818 GHSFQYLHQKQFLHRKFSFCSSVLINSFADQRGHYPSKCVVEKILVLGFRKEPSSVTTHS 877
G S + L + + F ++ ++N + ++K+ VLG P V ++
Sbjct: 862 GESLEVLERGAYTQVIFLARNNTIVNELVRVTSE-GAGLQLQKVTVLGVATAPQQVLSNG 920
Query: 878 SDGKDQPVA-FTYCAKTSILSL 898
PV+ FTY T +L +
Sbjct: 921 -----VPVSNFTYSPDTKVLDI 937
>gi|157364974 sucrase-isomaltase [Homo sapiens]
Length = 1827
Score = 298 bits (763), Expect = 2e-80
Identities = 205/674 (30%), Positives = 324/674 (48%), Gaps = 70/674 (10%)
Query: 277 GRTIGIFWLNASETLVEINTEPAVEYTLTQMGPVAAKQKVRSRTHVHWMSESGIIDVFLL 336
G++ G+F +N++ + I P V Y +T GI+D ++L
Sbjct: 289 GKSFGVFLMNSNAMEIFIQPTPIVTYRVT----------------------GGILDFYIL 326
Query: 337 TGPTPSDVFKQYSHLTGTQAMPPLFSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDAMW 396
G TP V +QY L G AMP ++LG+ RWNY+ VK V E IP+D
Sbjct: 327 LGDTPEQVVQQYQQLVGLPAMPAYWNLGFQLSRWNYKSLDVVKEVVRRNREAGIPFDTQV 386
Query: 397 LDIEHTEGKRYFTWDKNRFPNPKRMQELLRSKKRKLVVISDPHIKID-----PDYSVYVK 451
DI++ E K+ FT+D+ F + + L +K V+I DP I I Y+ Y +
Sbjct: 387 TDIDYMEDKKDFTYDQVAFNGLPQFVQDLHDHGQKYVIILDPAISIGRRANGTTYATYER 446
Query: 452 AKDQGFFVKNQEGED-FEGVCWPGLSSYLDFTNPKVREWYSSLFAFPVYQGSTDILFLWN 510
Q ++ +G G WPGL+ Y DFTNP +W+++ + ++ LW
Sbjct: 447 GNTQHVWINESDGSTPIIGEVWPGLTVYPDFTNPNCIDWWANECS--IFHQEVQYDGLWI 504
Query: 511 DMNEPSVF-RGPEQTMQKNAIHHG----------------------NW-EHRELHNIYGF 546
DMNE S F +G + N +++ NW + ++H++YG+
Sbjct: 505 DMNEVSSFIQGSTKGCNVNKLNYPPFTPDILDKLMYSKTICMDAVQNWGKQYDVHSLYGY 564
Query: 547 YHQMATAEGLIKRSKGKERPFVLTRSFFAGSQKYGAVWTGDNTAEWSNLKISIPMLLTLS 606
+AT + + K K R F+LTRS FAGS ++ A W GDNTA W ++ SI +L S
Sbjct: 565 SMAIATEQAVQKVFPNK-RSFILTRSTFAGSGRHAAHWLGDNTASWEQMEWSITGMLEFS 623
Query: 607 ITGISFCGADIGGFIGNPETELLVRWYQAGAYQPFFRGHATMNTKRREPWLFGEEH--TR 664
+ GI GADI GF+ EL RW Q GA+ PF R H + + ++P FG+ +
Sbjct: 624 LFGIPLVGADICGFVAETTEELCRRWMQLGAFYPFSRNHNSDGYEHQDPAFFGQNSLLVK 683
Query: 665 LIREAIRERYGLLPYWYSLFYHAHVASQPVMRPLWVEFPDELKTFDMEDEYMLGSALLVH 724
R+ + RY LLP+ Y+LFY AHV + V RP+ EF ++ ++ + E++ G ALL+
Sbjct: 684 SSRQYLTIRYTLLPFLYTLFYKAHVFGETVARPVLHEFYEDTNSWIEDTEFLWGPALLIT 743
Query: 725 PVTEPKATTVDVFLPGSNEVWYDYKTFAH--WEGGCTVKIPVALDTIPVFQRGGSVIPIK 782
PV + A TV ++P + +WYDY++ A W V + + D I + RGG +IPI+
Sbjct: 744 PVLKQGADTVSAYIP--DAIWYDYESGAKRPWRKQ-RVDMYLPADKIGLHLRGGYIIPIQ 800
Query: 783 TTVGKSTGWMTESSYGLRVALSTKGSSVGELYLDDGHSFQYLHQKQFLHRKFSFCSSVLI 842
+T ++ GL VAL ++ G+ + DDG + + ++ FS ++ L
Sbjct: 801 EPDVTTTA-SRKNPLGLIVALGENNTAKGDFFWDDGETKDTIQNGNYILYTFSVSNNTLD 859
Query: 843 NSFADQRGHYPSKCVVEKILVLGFRKEPSSVTTHSSDGKDQPV----AFTYCAKTSILSL 898
+ + + +LG SVT +QP+ FTY A +L +
Sbjct: 860 IVCTHSSYQEGTTLAFQTVKILGL---TDSVTEVRVAENNQPMNAHSNFTYDASNQVLLI 916
Query: 899 EKLSLNIATDWEVR 912
L LN+ ++ V+
Sbjct: 917 ADLKLNLGRNFSVQ 930
Score = 259 bits (663), Expect = 6e-69
Identities = 210/815 (25%), Positives = 347/815 (42%), Gaps = 116/815 (14%)
Query: 176 NEEETSVDTSQENQEDLGLWEEKFGKFVDIKANGPSSIGLDFSLHGF------------- 222
N T + T ++ D+ + E FG + I+ + D L GF
Sbjct: 1049 NIPTTPISTYEDRLYDVEIKENPFG--IQIRRRSSGRVIWDSWLPGFAFNDQFIQISTRL 1106
Query: 223 --EHLYGIPQHAESHQLKNTGDGDAYRLYNLDVY-GYQIYDKMGIYGSVPYLLA-HKLGR 278
E++YG + E K + + + ++ D GY K+ YG PY +A + G
Sbjct: 1107 PSEYIYGFGE-VEHTAFKRDLNWNTWGMFTRDQPPGY----KLNSYGFHPYYMALEEEGN 1161
Query: 279 TIGIFWLNASETLVEINTEPAVEYTLTQMGPVAAKQKVRSRTHVHWMSESGIIDVFLLTG 338
G+F LN++ V PA+ Y GI+D ++ G
Sbjct: 1162 AHGVFLLNSNAMDVTFQPTPALTYRTV----------------------GGILDFYMFLG 1199
Query: 339 PTPSDVFKQYSHLTGTQAMPPLFSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDAMWLD 398
PTP KQY + G MP ++LG+ CR+ Y + +V+ + +IPYD + D
Sbjct: 1200 PTPEVATKQYHEVIGHPVMPAYWALGFQLCRYGYANTSEVRELYDAMVAANIPYDVQYTD 1259
Query: 399 IEHTEGKRYFTWDKNRFPNPKRMQELLRSKKRKLVVISDPHIKID--PDYSVYVKAKDQG 456
I++ E + FT + F + + + +R + + ++I DP I + Y + + +
Sbjct: 1260 IDYMERQLDFTIGE-AFQDLPQFVDKIRGEGMRYIIILDPAISGNETKTYPAFERGQQND 1318
Query: 457 FFVKNQEGEDFEGVCW-------PGLS------------------SYLDFTNPKVREWYS 491
FVK D +CW P ++ ++ DF EW++
Sbjct: 1319 VFVKWPNTND---ICWAKVWPDLPNITIDKTLTEDEAVNASRAHVAFPDFFRTSTAEWWA 1375
Query: 492 SLFAFPVYQGSTDILFLWNDMNEPSVFRG------------------PEQTMQKNAIHH- 532
Y LW DMNEPS F PE T + + +H
Sbjct: 1376 REIV-DFYNEKMKFDGLWIDMNEPSSFVNGTTTNQCRNDELNYPPYFPELTKRTDGLHFR 1434
Query: 533 -------------GNWEHRELHNIYGFYHQMATAEGLIKRSKGKERPFVLTRSFFAGSQK 579
+ H ++HN+YG + QM ++++ GK R V++RS + S +
Sbjct: 1435 TICMEAEQILSDGTSVLHYDVHNLYG-WSQMKPTHDALQKTTGK-RGIVISRSTYPTSGR 1492
Query: 580 YGAVWTGDNTAEWSNLKISIPMLLTLSITGISFCGADIGGFIGNPETELLVRWYQAGAYQ 639
+G W GDN A W N+ SI ++ S+ G+S+ GADI GF N E L RW Q GA+
Sbjct: 1493 WGGHWLGDNYARWDNMDKSIIGMMEFSLFGMSYTGADICGFFNNSEYHLCTRWMQLGAFY 1552
Query: 640 PFFRGHATMNTKRREPWLFGEEHTRLIREAIRERYGLLPYWYSLFYHAHVASQPVMRPLW 699
P+ R H NT+R++P + E + R + RY LLPY+Y+ + H V+RPL
Sbjct: 1553 PYSRNHNIANTRRQDPASWNETFAEMSRNILNIRYTLLPYFYTQMHEIHANGGTVIRPLL 1612
Query: 700 VEFPDELKTFDMEDEYMLGSALLVHPVTEPKATTVDVFLPGSNEVWYDYKTFAH-WEGGC 758
EF DE T+D+ +++ G A +V PV EP TV+ ++P N W+DY T G
Sbjct: 1613 HEFFDEKPTWDIFKQFLWGPAFMVTPVLEPYVQTVNAYVP--NARWFDYHTGKDIGVRGQ 1670
Query: 759 TVKIPVALDTIPVFQRGGSVIPIKTTVGKSTGWMTESSYGLRVALSTKGSSVGELYLDDG 818
+ DTI + RGG ++P + ++T + + L VA + G L+ DDG
Sbjct: 1671 FQTFNASYDTINLHVRGGHILPCQEP-AQNTFYSRQKHMKLIVAADDNQMAQGSLFWDDG 1729
Query: 819 HSFQYLHQKQFLHRKFSFCSSVLINSFADQRGHYPSKCVVEKILVLGFRKEPSSVTTHSS 878
S + +L +F+ + L ++ + S+ + + V G P + T +
Sbjct: 1730 ESIDTYERDLYLSVQFNLNQTTLTSTILKRGYINKSETRLGSLHVWGKGTTPVNAVTLTY 1789
Query: 879 DGKDQPVAFTYCAKTSILSLEKLSLNIATDWEVRI 913
+G + F IL ++ + N+ + + I
Sbjct: 1790 NGNKNSLPFNEDTTNMILRIDLTTHNVTLEEPIEI 1824
>gi|221316699 maltase-glucoamylase [Homo sapiens]
Length = 1857
Score = 282 bits (722), Expect = 9e-76
Identities = 207/731 (28%), Positives = 340/731 (46%), Gaps = 75/731 (10%)
Query: 224 HLYGIPQHAESHQLKNTGDGDAYRLYNLDVYGYQIYDKMGIYGSVPYLLAHK--LGRTIG 281
++YG+ +H Q ++ + + ++N D + +YG+ + L + G + G
Sbjct: 262 NVYGLGEHVHQ-QYRHDMNWKTWPIFNRDTTPNG--NGTNLYGAQTFFLCLEDASGLSFG 318
Query: 282 IFWLNASETLVEINTEPAVEYTLTQMGPVAAKQKVRSRTHVHWMSESGIIDVFLLTGPTP 341
+F +N++ V + PA+ Y GI+D ++ G TP
Sbjct: 319 VFLMNSNAMEVVLQPAPAITYRTI----------------------GGILDFYVFLGNTP 356
Query: 342 SDVFKQYSHLTGTQAMPPLFSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDAMWLDIEH 401
V ++Y L G A+P ++LG+H R+ Y +++ V +PYD DI++
Sbjct: 357 EQVVQEYLELIGRPALPSYWALGFHLSRYEYGTLDNMREVVERNRAAQLPYDVQHADIDY 416
Query: 402 TEGKRYFTWDKNRFPNPKRMQELLRSKKRKLVVISDPHIKIDPD----YSVYVKAKDQGF 457
+ +R FT+D F L + +KLV+I DP I + Y Y + D
Sbjct: 417 MDERRDFTYDSVDFKGFPEFVNELHNNGQKLVIIVDPAISNNSSSSKPYGPYDRGSDMKI 476
Query: 458 FVKNQEG-EDFEGVCWPGLSSYLDFTNPKVREWYSSLFAFPVYQGSTDILFLWNDMNEPS 516
+V + +G G WPG + + D+TNP W++ F ++ + +W DMNE S
Sbjct: 477 WVNSSDGVTPLIGEVWPGQTVFPDYTNPNCAVWWTK--EFELFHNQVEFDGIWIDMNEVS 534
Query: 517 VF-------------RGPE------------QTMQKNAIHHGNWEHRELHNIYGFYHQMA 551
F P +T+ +A+ H ++ ++HN+YG+ +A
Sbjct: 535 NFVDGSVSGCSTNNLNNPPFTPRILDGYLFCKTLCMDAVQHWGKQY-DIHNLYGYSMAVA 593
Query: 552 TAEGLIKRSKGKERPFVLTRSFFAGSQKYGAVWTGDNTAEWSNLKISIPMLLTLSITGIS 611
TAE K +R F+LTRS FAGS K+ A W GDNTA W +L+ SIP +L ++ GI
Sbjct: 594 TAEAA-KTVFPNKRSFILTRSTFAGSGKFAAHWLGDNTATWDDLRWSIPGVLEFNLFGIP 652
Query: 612 FCGADIGGFIGNPETELLVRWYQAGAYQPFFRGHATMNTKRREPWLFGEEHTRL--IREA 669
G DI GF + EL RW Q GA+ PF R H K ++P FG + L R
Sbjct: 653 MVGPDICGFALDTPEELCRRWMQLGAFYPFSRNHNGQGYKDQDPASFGADSLLLNSSRHY 712
Query: 670 IRERYGLLPYWYSLFYHAHVASQPVMRPLWVEFPDELKTFDMEDEYMLGSALLVHPVTEP 729
+ RY LLPY Y+LF+ AH V RPL EF ++ T+D+ +++ G LL+ PV +
Sbjct: 713 LNIRYTLLPYLYTLFFRAHSRGDTVARPLLHEFYEDNSTWDVHQQFLWGPGLLITPVLDE 772
Query: 730 KATTVDVFLPGSNEVWYDYKTFA--HWEGGCTVKIPVALDTIPVFQRGGSVIPIKTTVGK 787
A V ++P + VWYDY+T + W V++ + D I + RGG + P +
Sbjct: 773 GAEKVMAYVP--DAVWYDYETGSQVRWRKQ-KVEMELPGDKIGLHLRGGYIFPTQQP-NT 828
Query: 788 STGWMTESSYGLRVALSTKGSSVGELYLDDGHSFQYLHQKQFLHRKFSFCSSVLINSFAD 847
+T ++ GL +AL + GEL+ D+G + + K +L +FS + L + +
Sbjct: 829 TTLASRKNPLGLIIALDENKEAKGELFWDNGETKDTVANKVYLLCEFSVTQNRLEVNISQ 888
Query: 848 QRGHYPSKCVVEKILVLGFRKEPSSVTT-HSSDGKDQPVAFTYCAKTSILSLEKLSLNI- 905
P+ +I +LG +EPS+VT H+ TY + + + + L +
Sbjct: 889 STYKDPNNLAFNEIKILG-TEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDIDLLLG 947
Query: 906 ---ATDWEVRI 913
+W ++I
Sbjct: 948 EAYTVEWSIKI 958
Score = 247 bits (631), Expect = 3e-65
Identities = 199/716 (27%), Positives = 320/716 (44%), Gaps = 104/716 (14%)
Query: 261 KMGIYGSVPYLLA-HKLGRTIGIFWLNASETLVEINTEPAVEYTLTQMGPVAAKQKVRSR 319
K YG PY + + G G+ LN++ V PA+ Y T
Sbjct: 1163 KKNSYGVHPYYMGLEEDGSAHGVLLLNSNAMDVTFQPLPALTYRTT-------------- 1208
Query: 320 THVHWMSESGIIDVFLLTGPTPSDVFKQYSHLTGTQAMPPLFSLGYHQCRWNYEDEQDVK 379
G++D ++ GPTP V +QY+ L G M P +SLG+ CR+ Y+++ ++
Sbjct: 1209 --------GGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEIA 1260
Query: 380 AVDAGFDEHDIPYDAMWLDIEHTEGKRYFTWDKNRFPNPKRMQELLRSKKRKLVVISDPH 439
++ IPYD + DI++ E + FT +F + +++ ++++I DP
Sbjct: 1261 SLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSP-KFAGFPALINRMKADGMRVILILDPA 1319
Query: 440 IKIDPD--YSVYVKAKDQGFFVKN-QEGEDFEGVCWPG-----LSSYLDFTNPKVREWYS 491
I + Y + + + F+K +G+ G WP ++ LD+ + E Y
Sbjct: 1320 ISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWDSQV--ELYR 1377
Query: 492 SLFAFP-VYQGST--------------------DILF--LWNDMNEPSVF-RGPEQTMQK 527
+ AFP ++ ST + F +W DMNEPS F G +
Sbjct: 1378 AYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCR 1437
Query: 528 NA-IHHGNW------------------------------EHRELHNIYGFYHQMATAEGL 556
+A ++H + +H +HN+YG+ T E +
Sbjct: 1438 DASLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQHYNVHNLYGWSQTRPTYEAV 1497
Query: 557 IKRSKGKERPFVLTRSFFAGSQKYGAVWTGDNTAEWSNLKISIPMLLTLSITGISFCGAD 616
+ +R V+TRS F S ++ W GDNTA W LK SI ++ S+ GIS+ GAD
Sbjct: 1498 --QEVTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGAD 1555
Query: 617 IGGFIGNPETELLVRWYQAGAYQPFFRGHATMNTKRREPWLFGEEHTRLIREAIRERYGL 676
I GF + E E+ VRW Q GA+ PF R H T+ T+R++P + + R ++ RY L
Sbjct: 1556 ICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDVAFVNISRTVLQTRYTL 1615
Query: 677 LPYWYSLFYHAHVASQPVMRPLWVEFPDELKTFDMEDEYMLGSALLVHPVTEPKATTVDV 736
LPY Y+L + AH V+RPL EF + T+D++ +++LG A LV PV E A V
Sbjct: 1616 LPYLYTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTA 1675
Query: 737 FLPGSNEVWYDYKTFAHWEG-GCTVKIPVALDTIPVFQRGGSVIPIKTTVGKSTGWMTES 795
+ P + WYDY T G +P LD I + RGG ++P + +T +
Sbjct: 1676 YFPRAR--WYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEP-ALNTHLSRQK 1732
Query: 796 SYGLRVALSTKGSSVGELYLDDGHSFQYLHQKQFLHRKFS-----FCSSVLINSFADQRG 850
G ++AL +G++ G L+ DDG S + + FS S ++ N++ G
Sbjct: 1733 FMGFKIALDDEGTAGGWLFWDDGQSIDTYGKGLYYLASFSASQNTMQSHIIFNNYI--TG 1790
Query: 851 HYPSKCVVEKILVLGFRKEPSSVTTHSSDGKDQPVAFTYCAKTSILSLEKLSLNIA 906
P K + I + G P + + S G +F T +LS++ NI+
Sbjct: 1791 TNPLK--LGYIEIWGVGSVPVTSVSISVSGMVITPSFNNDPTTQVLSIDVTDRNIS 1844
>gi|169171979 PREDICTED: similar to sucrase-isomaltase [Homo sapiens]
Length = 1492
Score = 248 bits (632), Expect = 2e-65
Identities = 199/716 (27%), Positives = 320/716 (44%), Gaps = 104/716 (14%)
Query: 261 KMGIYGSVPYLLA-HKLGRTIGIFWLNASETLVEINTEPAVEYTLTQMGPVAAKQKVRSR 319
K YG PY + + G G+ LN++ V PA+ Y T
Sbjct: 798 KKNSYGVHPYYMGLEEDGSAHGVLLLNSNAMDVTFQPLPALTYRTT-------------- 843
Query: 320 THVHWMSESGIIDVFLLTGPTPSDVFKQYSHLTGTQAMPPLFSLGYHQCRWNYEDEQDVK 379
G++D ++ GPTP V +QY+ L G M P +SLG+ CR+ Y+++ ++
Sbjct: 844 --------GGVLDFYVFLGPTPELVTQQYTELIGRPVMVPYWSLGFQLCRYGYQNDSEIS 895
Query: 380 AVDAGFDEHDIPYDAMWLDIEHTEGKRYFTWDKNRFPNPKRMQELLRSKKRKLVVISDPH 439
++ IPYD + DI++ E + FT +F + +++ ++++I DP
Sbjct: 896 SLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSP-KFAGFPALINRMKADGMRVILILDPA 954
Query: 440 IKIDPD--YSVYVKAKDQGFFVKN-QEGEDFEGVCWPG-----LSSYLDFTNPKVREWYS 491
I + Y + + + F+K +G+ G WP ++ LD+ + E Y
Sbjct: 955 ISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKVWPDFPDVVVNGSLDWDSQV--ELYR 1012
Query: 492 SLFAFP-VYQGST--------------------DILF--LWNDMNEPSVF-RGPEQTMQK 527
+ AFP ++ ST + F +W DMNEPS F G +
Sbjct: 1013 AYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCR 1072
Query: 528 NA-IHHGNW------------------------------EHRELHNIYGFYHQMATAEGL 556
+A ++H + +H +HN+YG+ T E +
Sbjct: 1073 DASLNHPPYMPYLESRDRGLSSKTLCMESQQILPDGSPVQHYNVHNLYGWSQTRPTYEAV 1132
Query: 557 IKRSKGKERPFVLTRSFFAGSQKYGAVWTGDNTAEWSNLKISIPMLLTLSITGISFCGAD 616
+ +R V+TRS F S ++ W GDNTA W LK SI ++ S+ GIS+ GAD
Sbjct: 1133 --QEVTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSIIGMMEFSLFGISYTGAD 1190
Query: 617 IGGFIGNPETELLVRWYQAGAYQPFFRGHATMNTKRREPWLFGEEHTRLIREAIRERYGL 676
I GF + E E+ VRW Q GA+ PF R H T+ T+R++P + + R ++ RY L
Sbjct: 1191 ICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDVAFVNISRTVLQTRYTL 1250
Query: 677 LPYWYSLFYHAHVASQPVMRPLWVEFPDELKTFDMEDEYMLGSALLVHPVTEPKATTVDV 736
LPY Y+L + AH V+RPL EF + T+D++ +++LG A LV PV E A V
Sbjct: 1251 LPYLYTLMHKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNARNVTA 1310
Query: 737 FLPGSNEVWYDYKTFAHWEG-GCTVKIPVALDTIPVFQRGGSVIPIKTTVGKSTGWMTES 795
+ P + WYDY T G +P LD I + RGG ++P + +T +
Sbjct: 1311 YFPRAR--WYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEP-ALNTHLSRQK 1367
Query: 796 SYGLRVALSTKGSSVGELYLDDGHSFQYLHQKQFLHRKFS-----FCSSVLINSFADQRG 850
G ++AL +G++ G L+ DDG S + + FS S ++ N++ G
Sbjct: 1368 FMGFKIALDDEGTAGGWLFWDDGQSIDTYGKGLYYLASFSASQNTMQSHIIFNNYI--TG 1425
Query: 851 HYPSKCVVEKILVLGFRKEPSSVTTHSSDGKDQPVAFTYCAKTSILSLEKLSLNIA 906
P K + I + G P + + S G +F T +LS++ NI+
Sbjct: 1426 TNPLK--LGYIEIWGVGSVPVTSVSISVSGMVITPSFNNDPTTQVLSIDVTDRNIS 1479
Score = 216 bits (550), Expect = 8e-56
Identities = 168/607 (27%), Positives = 277/607 (45%), Gaps = 64/607 (10%)
Query: 357 MPPLFSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDAMWLDIEHTEGKRYFTWDKNRFP 416
M P +SLG+ CR+ Y+++ ++ ++ IPYD + DI++ E + FT +F
Sbjct: 1 MVPYWSLGFQLCRYGYQNDSEIASLYDEMVAAQIPYDVQYSDIDYMERQLDFTLSP-KFA 59
Query: 417 NPKRMQELLRSKKRKLVVISDPHIKIDPD--YSVYVKAKDQGFFVKN-QEGEDFEGVCWP 473
+ +++ ++++I DP I + Y + + + F+K +G+ G +
Sbjct: 60 GFPALINRMKADGMRVILILDPAISGNETQPYPAFTRGVEDDVFIKYPNDGDIVWGKLYR 119
Query: 474 GLSSYLDFTNPKVREWYS----SLFAFPVY-QGSTDILFLWNDMNEPSVF-RGPEQTMQK 527
++ DF +W+ L+ P + S +W DMNEPS F G +
Sbjct: 120 AYVAFPDFFRNSTAKWWKREIEELYNNPQNPERSLKFDGMWIDMNEPSSFVNGAVSPGCR 179
Query: 528 NA-IHHGNW------------------------------EHRELHNIYGFYHQMATAEGL 556
+A ++H + +H +HN+YG+ T E +
Sbjct: 180 DASLNHPPYMPHLESRDRGLSSKTLCMESQQILPDGSLVQHYNVHNLYGWSQTRPTYEAV 239
Query: 557 IKRSKGKERPFVLTRSFFAGSQKYGAVWTGDNTAEWSNLKISIPMLLTLSITGISFC--- 613
+ +R V+TRS F S ++ W GDNTA W LK SI I F
Sbjct: 240 --QEVTGQRGVVITRSTFPSSGRWAGHWLGDNTAAWDQLKKSI-------IGSFYFLLFQ 290
Query: 614 -GADIGGFIGNPETELLVRWYQAGAYQPFFRGHATMNTKRREPWLFGEEHTRLIREAIRE 672
GADI GF + E E+ VRW Q GA+ PF R H T+ T+R++P + + R ++
Sbjct: 291 TGADICGFFQDAEYEMCVRWMQLGAFYPFSRNHNTIGTRRQDPVSWDAAFVNISRNVLQT 350
Query: 673 RYGLLPYWYSLFYHAHVASQPVMRPLWVEFPDELKTFDMEDEYMLGSALLVHPVTEPKAT 732
RY LLPY Y+L AH V+RPL EF + T+D++ +++LG A LV PV E A
Sbjct: 351 RYTLLPYLYTLMQKAHTEGVTVVRPLLHEFVSDQVTWDIDSQFLLGPAFLVSPVLERNAR 410
Query: 733 TVDVFLPGSNEVWYDYKTFAHWEG-GCTVKIPVALDTIPVFQRGGSVIPIKTTVGKSTGW 791
V + P + WYDY T G +P LD I + RGG ++P + +T
Sbjct: 411 NVTAYFPRAR--WYDYYTGVDINARGEWKTLPAPLDHINLHVRGGYILPWQEP-ALNTHL 467
Query: 792 MTESSYGLRVALSTKGSSVGELYLDDGHSFQYLHQKQFLHRKFSFCSSVLINSFADQRGH 851
++ GL +AL + GEL+ DDG + + +K +L +FS + L + +
Sbjct: 468 SRKNPLGLIIALDENKEAKGELFWDDGQTKDTVAKKVYLLCEFSVTQNHLEVTISQSTYK 527
Query: 852 YPSKCVVEKILVLGFRKEPSSVTT-HSSDGKDQPVAFTYCAKTSILSLEKLSLNI----A 906
P+ +I +LG +EPS+VT H+ TY + + + ++L +
Sbjct: 528 DPNNLAFNEIKILGM-EEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDINLFLGEAYT 586
Query: 907 TDWEVRI 913
+W ++I
Sbjct: 587 VEWSIKI 593
>gi|153791946 hypothetical protein LOC57462 [Homo sapiens]
Length = 714
Score = 83.2 bits (204), Expect = 1e-15
Identities = 97/402 (24%), Positives = 150/402 (37%), Gaps = 78/402 (19%)
Query: 397 LDIEHTEGKRYFTWDKNRFPNPKRMQELLRSKKRKLVVISDPHIKIDPDYSVYVKAKDQG 456
+D +T F +D+ +FPN M LR ++ + P + + S + + ++
Sbjct: 352 IDDMYTPAYGDFDFDEVKFPNASDMFRRLRDAGFRVTLWVHPFVNYNS--SRFGEGVERE 409
Query: 457 FFVKNQEGEDFEGV-CWPGLSSYLDFTNPKVREWYS----------SLFAFPVYQGSTDI 505
FV+ G V W G+ + LDFT+PK R+W+ S+ +F G
Sbjct: 410 LFVREPTGRLPALVRWWNGIGAVLDFTHPKARDWFQGHLRRLRSRYSVASFKFDAGEVSY 469
Query: 506 L----FLWNDMNEPSVFRGPEQTMQKNAIHHGNWEHRELHNIYGFYHQMATAEGLIKRSK 561
L + + +PSV W R F+ G ++
Sbjct: 470 LPRDFSTYRPLPDPSV-----------------WSRRYTEMALPFFSLAEVRVGYQSQNI 512
Query: 562 GKERPFVLTRSFFAGSQKYGAVWTGDNTAEWSNLKISIPMLLTLSITGISFCGADIGGFI 621
S F +VW D L+ IP +LT+S+ G F D+ G
Sbjct: 513 ----------SCFFRLVDRDSVWGYD-----LGLRSLIPAVLTVSMLGYPFILPDMVG-- 555
Query: 622 GN-----------PETELLVRWYQAGAYQPFFRGHATMNTKRREPWLFGEEHTRLIREAI 670
GN PE EL +RW + A+ P + PW + E + ++
Sbjct: 556 GNAVPQRTAGGDVPERELYIRWLEVAAFMPAMQFSIP-------PWRYDAEVVAIAQKFA 608
Query: 671 RERYGLL-PYWYSLFYHAHVASQPVMRPLWVEFPDELKTFDMEDEYMLGSALLVHPVTEP 729
R L+ P L P++RPLW P + ++ ++++G LLV PV EP
Sbjct: 609 ALRASLVAPLLLELAGEVTDTGDPIVRPLWWIAPGDETAHRIDSQFLIGDTLLVAPVLEP 668
Query: 730 KATTVDVFLPGSNEVWYDYKTFAHWEGGCTVKIPVALDTIPV 771
DV+LP W YK G K PV L PV
Sbjct: 669 GKQERDVYLPAGK--WRSYK------GELFDKTPVLLTDYPV 702
>gi|193083163 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2a [Homo sapiens]
Length = 1394
Score = 32.7 bits (73), Expect = 1.6
Identities = 18/49 (36%), Positives = 23/49 (46%), Gaps = 3/49 (6%)
Query: 93 KPRFEVPDVLTSKPSTVRLISCSGDTGSLILADGKGDLKCHITANPFKV 141
K + EV DVLT +P + L G + DG LKC T +P V
Sbjct: 419 KAQLEVTDVLTDRPPPIIL---QGPANQTLAVDGTALLKCKATGDPLPV 464
>gi|61888896 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2b [Homo sapiens]
Length = 1378
Score = 32.7 bits (73), Expect = 1.6
Identities = 18/49 (36%), Positives = 23/49 (46%), Gaps = 3/49 (6%)
Query: 93 KPRFEVPDVLTSKPSTVRLISCSGDTGSLILADGKGDLKCHITANPFKV 141
K + EV DVLT +P + L G + DG LKC T +P V
Sbjct: 403 KAQLEVTDVLTDRPPPIIL---QGPANQTLAVDGTALLKCKATGDPLPV 448
>gi|209447073 synaptotagmin I [Homo sapiens]
Length = 422
Score = 31.6 bits (70), Expect = 3.5
Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 11/78 (14%)
Query: 169 KQRAAKENEEETSVDTSQENQEDLGLWEEKFGKFVDIKANGPSSIGLDFSLHGFEHLYGI 228
K +A K+++ ET + +E +E EEK GK LD+ + L GI
Sbjct: 115 KDQALKDDDAETGLTDGEEKEEPKE--EEKLGKL---------QYSLDYDFQNNQLLVGI 163
Query: 229 PQHAESHQLKNTGDGDAY 246
Q AE L G D Y
Sbjct: 164 IQAAELPALDMGGTSDPY 181
>gi|5032139 synaptotagmin I [Homo sapiens]
Length = 422
Score = 31.6 bits (70), Expect = 3.5
Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 11/78 (14%)
Query: 169 KQRAAKENEEETSVDTSQENQEDLGLWEEKFGKFVDIKANGPSSIGLDFSLHGFEHLYGI 228
K +A K+++ ET + +E +E EEK GK LD+ + L GI
Sbjct: 115 KDQALKDDDAETGLTDGEEKEEPKE--EEKLGKL---------QYSLDYDFQNNQLLVGI 163
Query: 229 PQHAESHQLKNTGDGDAY 246
Q AE L G D Y
Sbjct: 164 IQAAELPALDMGGTSDPY 181
>gi|209447070 synaptotagmin I [Homo sapiens]
Length = 422
Score = 31.6 bits (70), Expect = 3.5
Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 11/78 (14%)
Query: 169 KQRAAKENEEETSVDTSQENQEDLGLWEEKFGKFVDIKANGPSSIGLDFSLHGFEHLYGI 228
K +A K+++ ET + +E +E EEK GK LD+ + L GI
Sbjct: 115 KDQALKDDDAETGLTDGEEKEEPKE--EEKLGKL---------QYSLDYDFQNNQLLVGI 163
Query: 229 PQHAESHQLKNTGDGDAY 246
Q AE L G D Y
Sbjct: 164 IQAAELPALDMGGTSDPY 181
>gi|223972648 t-SNARE domain containing 1 [Homo sapiens]
Length = 513
Score = 31.2 bits (69), Expect = 4.6
Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Query: 14 EAVDKNIFRDCNKIAFYRRQKQWLSKKSTYQALLDSVTTDEDSTRFQIINEASKVPLLAE 73
+ + N+FR + + R Q L S Q L DS+ T + T I AS V +AE
Sbjct: 262 QEMSANVFRINSSVTSLERSLQSLGTPSDTQELRDSLHTAQQETNKTIAASASSVKQMAE 321
Query: 74 IYGIEGNIFRLKINEETPLKPRFE 97
+ + + + ++ +E P R +
Sbjct: 322 L--LRSSCPQERLQQERPQLDRLK 343
>gi|165377209 methyltransferase 5 domain containing 1 isoform 1
[Homo sapiens]
Length = 407
Score = 31.2 bits (69), Expect = 4.6
Identities = 18/70 (25%), Positives = 33/70 (47%)
Query: 387 EHDIPYDAMWLDIEHTEGKRYFTWDKNRFPNPKRMQELLRSKKRKLVVISDPHIKIDPDY 446
E IP +W + HT ++Y ++ + + QEL RS+ R ++ HI + D
Sbjct: 20 ESGIPNLGVWPNRIHTTAEKYREYEAREQTDQTQAQELHRSQDRDFETMAKLHIPVMVDE 79
Query: 447 SVYVKAKDQG 456
V+ + +G
Sbjct: 80 VVHCLSPQKG 89
>gi|165377202 methyltransferase 5 domain containing 1 isoform 2
[Homo sapiens]
Length = 273
Score = 31.2 bits (69), Expect = 4.6
Identities = 18/70 (25%), Positives = 33/70 (47%)
Query: 387 EHDIPYDAMWLDIEHTEGKRYFTWDKNRFPNPKRMQELLRSKKRKLVVISDPHIKIDPDY 446
E IP +W + HT ++Y ++ + + QEL RS+ R ++ HI + D
Sbjct: 20 ESGIPNLGVWPNRIHTTAEKYREYEAREQTDQTQAQELHRSQDRDFETMAKLHIPVMVDE 79
Query: 447 SVYVKAKDQG 456
V+ + +G
Sbjct: 80 VVHCLSPQKG 89
>gi|4503015 copine III [Homo sapiens]
Length = 537
Score = 30.4 bits (67), Expect = 7.9
Identities = 19/50 (38%), Positives = 27/50 (54%), Gaps = 1/50 (2%)
Query: 33 QKQWLSKKSTYQALLDSVTTDEDSTRFQIINEASKVPLLAEIYGIEGNIF 82
Q+Q S+ + D V TD D TR I+N AS++P+ I G+ G F
Sbjct: 413 QQQTASQYFVLLIITDGVITDLDETRQAIVN-ASRLPMSIIIVGVGGADF 461
>gi|119372317 xin actin-binding repeat containing 2 isoform 1 [Homo
sapiens]
Length = 3549
Score = 30.4 bits (67), Expect = 7.9
Identities = 25/105 (23%), Positives = 46/105 (43%), Gaps = 11/105 (10%)
Query: 132 CHITANPFKVDLVSEEEVVISINSLGQLYFEHLQILHKQRAAKENEEETSVDTSQENQED 191
C + KV E+E+ S N+ Q ++ H+ R+ +E + V TS+ +QE
Sbjct: 249 CAVPGGLAKVKKQFEDEITSSRNTFAQYQYQ-----HQNRSEQEAIHSSQVGTSRSSQE- 302
Query: 192 LGLWEEKFGKFVDIKANGPSSIGLDFSLHGFEHLYGIPQHAESHQ 236
+ E++ K I +G + H +H + Q ++ HQ
Sbjct: 303 MARNEQEGSKVQKIDVHGTEMVS-----HLEKHTEEVNQASQFHQ 342
>gi|119372315 xin actin-binding repeat containing 2 isoform 2 [Homo
sapiens]
Length = 938
Score = 30.4 bits (67), Expect = 7.9
Identities = 25/105 (23%), Positives = 46/105 (43%), Gaps = 11/105 (10%)
Query: 132 CHITANPFKVDLVSEEEVVISINSLGQLYFEHLQILHKQRAAKENEEETSVDTSQENQED 191
C + KV E+E+ S N+ Q ++ H+ R+ +E + V TS+ +QE
Sbjct: 249 CAVPGGLAKVKKQFEDEITSSRNTFAQYQYQ-----HQNRSEQEAIHSSQVGTSRSSQE- 302
Query: 192 LGLWEEKFGKFVDIKANGPSSIGLDFSLHGFEHLYGIPQHAESHQ 236
+ E++ K I +G + H +H + Q ++ HQ
Sbjct: 303 MARNEQEGSKVQKIDVHGTEMVS-----HLEKHTEEVNQASQFHQ 342
>gi|109637791 transcription factor-like nuclear regulator [Homo
sapiens]
Length = 2624
Score = 30.4 bits (67), Expect = 7.9
Identities = 35/155 (22%), Positives = 66/155 (42%), Gaps = 5/155 (3%)
Query: 2 EAAVKEEISLEDEAVDKNIFRDCNKIAFYRRQKQWLSKKSTYQ-ALLDSVTTDEDSTRFQ 60
+AA ++EI + E + N+ ++ N+ R Q + +S D + E + FQ
Sbjct: 717 KAAERKEILISQEEIGANVEKNENESCADRDTPQHMEDQSRKDFEEEDVILQPEKNDSFQ 776
Query: 61 IINEASKVPLLAEIYGIEGNIFRLKINEETPLKPRFEVPDVLTSKPSTVRLISCSGDTGS 120
+ + + +L E ++ N K+N+ L+ RF+ P + + R IS +
Sbjct: 777 NV-QPDEPKVLNECLSVQENNKANKLNQVPILRTRFQKPKPNIGRGTGRREISSKEEVLE 835
Query: 121 LILADGKGDLKCHITANPFKVDLVSEEEVVISINS 155
IL G+ T ++D +E V IN+
Sbjct: 836 KILVSGEMAAALRETV---RLDTSPKEMVPAEINT 867
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,217,474
Number of Sequences: 37866
Number of extensions: 1686914
Number of successful extensions: 3496
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 3406
Number of HSP's gapped (non-prelim): 34
length of query: 914
length of database: 18,247,518
effective HSP length: 111
effective length of query: 803
effective length of database: 14,044,392
effective search space: 11277646776
effective search space used: 11277646776
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.