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Search of human proteins with 62526043
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62526043 chymotrypsin C preproprotein [Homo sapiens]
(268 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62526043 chymotrypsin C preproprotein [Homo sapiens] 566 e-162
gi|15559207 elastase 2A preproprotein [Homo sapiens] 345 2e-95
gi|58331211 elastase 2B preproprotein [Homo sapiens] 319 2e-87
gi|6679625 elastase 3B, pancreatic preproprotein [Homo sapiens] 302 2e-82
gi|236460050 elastase 3A, pancreatic preproprotein [Homo sapiens] 288 5e-78
gi|58331209 chymotrypsin-like elastase family, member 1 [Homo sa... 254 7e-68
gi|118498350 chymotrypsin B2 [Homo sapiens] 192 2e-49
gi|118498341 chymotrypsin B1 [Homo sapiens] 189 2e-48
gi|4503137 chymotrypsin-like [Homo sapiens] 180 1e-45
gi|110815798 ovochymase 1 [Homo sapiens] 167 1e-41
gi|4503627 coagulation factor XI precursor [Homo sapiens] 159 2e-39
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 157 7e-39
gi|33695155 hepsin [Homo sapiens] 154 1e-37
gi|4504481 hepsin [Homo sapiens] 154 1e-37
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 154 1e-37
gi|4505881 plasminogen [Homo sapiens] 153 1e-37
gi|170932492 transmembrane protease, serine 5 [Homo sapiens] 153 1e-37
gi|29244926 corin [Homo sapiens] 152 2e-37
gi|117956391 protease, serine, 33 [Homo sapiens] 152 2e-37
gi|4758508 transmembrane protease, serine 11D [Homo sapiens] 150 9e-37
gi|187761337 transmembrane protease, serine 11B [Homo sapiens] 149 2e-36
gi|148613878 acrosin precursor [Homo sapiens] 149 2e-36
gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sa... 149 3e-36
gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo sap... 149 3e-36
gi|68508970 tryptase beta 2 precursor [Homo sapiens] 147 1e-35
gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens] 145 3e-35
gi|11545839 protease, serine, 22 [Homo sapiens] 145 3e-35
gi|223942069 enterokinase precursor [Homo sapiens] 144 8e-35
gi|194018492 transmembrane protease, serine 11F [Homo sapiens] 143 2e-34
gi|13994276 marapsin [Homo sapiens] 142 2e-34
>gi|62526043 chymotrypsin C preproprotein [Homo sapiens]
Length = 268
Score = 566 bits (1458), Expect = e-162
Identities = 268/268 (100%), Positives = 268/268 (100%)
Query: 1 MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCG 60
MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCG
Sbjct: 1 MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCG 60
Query: 61 GTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRN 120
GTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRN
Sbjct: 61 GTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRN 120
Query: 121 DIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPV 180
DIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPV
Sbjct: 121 DIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPV 180
Query: 181 VDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSR 240
VDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSR
Sbjct: 181 VDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSR 240
Query: 241 RGCNTRKKPVVYTRVSAYIDWINEKMQL 268
RGCNTRKKPVVYTRVSAYIDWINEKMQL
Sbjct: 241 RGCNTRKKPVVYTRVSAYIDWINEKMQL 268
>gi|15559207 elastase 2A preproprotein [Homo sapiens]
Length = 269
Score = 345 bits (886), Expect = 2e-95
Identities = 168/265 (63%), Positives = 204/265 (76%), Gaps = 4/265 (1%)
Query: 1 MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCG 60
M+ +L+ L+A A SCG P++PP ++ RVVGGE+ARP+SWPWQ+SLQY N W HTCG
Sbjct: 1 MIRTLLLSTLVAGALSCGDPTYPPYVT-RVVGGEEARPNSWPWQVSLQYSSNGKWYHTCG 59
Query: 61 GTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLR- 119
G+LIA+++VLTAAHCIS++RTYRV +G++NL V E GSL V V I VHK WN+ +
Sbjct: 60 GSLIANSWVLTAAHCISSSRTYRVGLGRHNLYVA-ESGSLAVSVSKIVVHKDWNSNQISK 118
Query: 120 -NDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQ 178
NDIAL+KLA V L+D IQ+ACLP ++LP +YPCYVTGWGRL TNG + D LQQG
Sbjct: 119 GNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRL 178
Query: 179 PVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFG 238
VVD+ATCS WWG VK +M+CAGGDGVIS+CNGDSGGPLNCQ +G W+V GIVSFG
Sbjct: 179 LVVDYATCSSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFG 238
Query: 239 SRRGCNTRKKPVVYTRVSAYIDWIN 263
SR GCN KP V+TRVS YIDWIN
Sbjct: 239 SRLGCNYYHKPSVFTRVSNYIDWIN 263
>gi|58331211 elastase 2B preproprotein [Homo sapiens]
Length = 269
Score = 319 bits (817), Expect = 2e-87
Identities = 157/265 (59%), Positives = 194/265 (73%), Gaps = 4/265 (1%)
Query: 1 MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCG 60
M+ +L+ L+A A SCGV ++ P++S R++GGE+ARP+SWPWQ+SLQY N W HTCG
Sbjct: 1 MIRTLLLSTLVAGALSCGVSTYAPDMS-RMLGGEEARPNSWPWQVSLQYSSNGQWYHTCG 59
Query: 61 GTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNA--LLL 118
G+LIA+++VLTAAHCIS++ YRV +G++NL V E GSL V V I VHK WN+ +
Sbjct: 60 GSLIANSWVLTAAHCISSSGIYRVMLGQHNLYVA-ESGSLAVSVSKIVVHKDWNSDQVSK 118
Query: 119 RNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQ 178
NDIAL+KLA V L+D IQ+ACLP ++LP +YPCYVTGWGRL TNG + D L+QG
Sbjct: 119 GNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRL 178
Query: 179 PVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFG 238
VVD+ATCS WWG VK M+CAGGDGVI CNGDSGGPLNCQ +G WEV GI S
Sbjct: 179 LVVDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLT 238
Query: 239 SRRGCNTRKKPVVYTRVSAYIDWIN 263
S GCN KP ++TRVS Y DWIN
Sbjct: 239 SVLGCNYYYKPSIFTRVSNYNDWIN 263
>gi|6679625 elastase 3B, pancreatic preproprotein [Homo sapiens]
Length = 270
Score = 302 bits (774), Expect = 2e-82
Identities = 149/267 (55%), Positives = 190/267 (71%), Gaps = 6/267 (2%)
Query: 1 MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCG 60
ML + L+A AS G PS P S+RVV GEDA P+SWPWQ+SLQY K+ ++ HTCG
Sbjct: 2 MLRLLSSLLLVAVASGYGPPSSRP--SSRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCG 59
Query: 61 GTLIASNFVLTAAHCISNTRTYRVAVGKNNLEV-EDEEGSLFVGVDTIHVHKRWN--ALL 117
G+LIA ++V+TA HCIS++RTY+V +G+ + V E E + + + VH WN +
Sbjct: 60 GSLIAPDWVVTAGHCISSSRTYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVA 119
Query: 118 LRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGL 177
NDIALIKL+ +L D +Q+A LP +LP + PCY+TGWGRL+TNGP+ DKLQ+ L
Sbjct: 120 CGNDIALIKLSRSAQLGDAVQLASLPPAGDILPNETPCYITGWGRLYTNGPLPDKLQEAL 179
Query: 178 QPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSF 237
PVVD+ CSR +WWG VKKTMVCAGGD + S CNGDSGGPLNC E+G W+V G+ SF
Sbjct: 180 LPVVDYEHCSRWNWWGSSVKKTMVCAGGD-IRSGCNGDSGGPLNCPTEDGGWQVHGVTSF 238
Query: 238 GSRRGCNTRKKPVVYTRVSAYIDWINE 264
S GCNTR+KP V+TRVSA+IDWI E
Sbjct: 239 VSAFGCNTRRKPTVFTRVSAFIDWIEE 265
>gi|236460050 elastase 3A, pancreatic preproprotein [Homo sapiens]
Length = 270
Score = 288 bits (736), Expect = 5e-78
Identities = 146/267 (54%), Positives = 183/267 (68%), Gaps = 6/267 (2%)
Query: 1 MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCG 60
ML + L+A AS G PS + S+RVV GEDA P+SWPWQ+SLQY K+ ++ HTCG
Sbjct: 2 MLRLLSSLLLVAVASGYGPPS--SHSSSRVVHGEDAVPYSWPWQVSLQYEKSGSFYHTCG 59
Query: 61 GTLIASNFVLTAAHCISNTRTYRVAVGKNNLEV-EDEEGSLFVGVDTIHVHKRWN--ALL 117
G+LIA ++V+TA HCIS TY+V +G+ NL V E E + + + + VH WN +
Sbjct: 60 GSLIAPDWVVTAGHCISRDLTYQVVLGEYNLAVKEGPEQVIPINSEELFVHPLWNRSCVA 119
Query: 118 LRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGL 177
NDIALIKL+ +L D +Q+A LP +LP PCY+TGWGRL+TNGP+ DKLQQ
Sbjct: 120 CGNDIALIKLSRSAQLGDAVQLASLPPAGDILPNKTPCYITGWGRLYTNGPLPDKLQQAR 179
Query: 178 QPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSF 237
PVVD+ CSR +WWG VKKTMVCAGG + S CNGDSGGPLNC E+G W+V G+ SF
Sbjct: 180 LPVVDYKHCSRWNWWGSTVKKTMVCAGG-YIRSGCNGDSGGPLNCPTEDGGWQVHGVTSF 238
Query: 238 GSRRGCNTRKKPVVYTRVSAYIDWINE 264
S GCN KP V+TRVSA+IDWI E
Sbjct: 239 VSAFGCNFIWKPTVFTRVSAFIDWIEE 265
>gi|58331209 chymotrypsin-like elastase family, member 1 [Homo
sapiens]
Length = 258
Score = 254 bits (648), Expect = 7e-68
Identities = 126/242 (52%), Positives = 161/242 (66%), Gaps = 4/242 (1%)
Query: 24 PNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYR 83
P +ARVVGG +A +SWP QISLQY + HTCGGTLI N+V+TAAHC+ +T+R
Sbjct: 13 PETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQKTFR 72
Query: 84 VAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNA--LLLRNDIALIKLAEHVELSDTIQVAC 141
V G +NL D +V V I VH WN+ + DIAL++LA+ V L+ +Q+
Sbjct: 73 VVAGDHNLSQNDGTEQ-YVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGV 131
Query: 142 LPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMV 201
LP++ ++L + PCY+TGWG+ TNG +A LQQ P VD+A CS +WG VK TMV
Sbjct: 132 LPQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMV 191
Query: 202 CAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDW 261
CAGGDGV S C GDSGGPL+C L NG + V G+ SF S RGCN +KP V+T+VSAYI W
Sbjct: 192 CAGGDGVRSGCQGDSGGPLHC-LVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISW 250
Query: 262 IN 263
IN
Sbjct: 251 IN 252
>gi|118498350 chymotrypsin B2 [Homo sapiens]
Length = 263
Score = 192 bits (489), Expect = 2e-49
Identities = 112/259 (43%), Positives = 150/259 (57%), Gaps = 14/259 (5%)
Query: 9 ALLACASSCGVPSFPPNLS--ARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIAS 66
ALL CGVP+ P LS +R+V GEDA P SWPWQ+SLQ + T H CGG+LI+
Sbjct: 11 ALLGTTFGCGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQ---DKTGFHFCGGSLISE 67
Query: 67 NFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIK 126
++V+TAAHC RT V V + DEE + + + + +++ L + NDI L+K
Sbjct: 68 DWVVTAAHC--GVRTSDVVVAGEFDQGSDEENIQVLKIAKVFKNPKFSILTVNNDITLLK 125
Query: 127 LAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTN-GPIADKLQQGLQPVVDHAT 185
LA S T+ CLP D P C TGWG+ N DKLQQ P++ +A
Sbjct: 126 LATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKLQQAALPLLSNAE 185
Query: 186 CSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNT 245
C + WG R+ M+CAG GV S+C GDSGGPL CQ ++G+W + GIVS+GSR C+T
Sbjct: 186 CKKS--WGRRITDVMICAGASGV-SSCMGDSGGPLVCQ-KDGAWTLVGIVSWGSRT-CST 240
Query: 246 RKKPVVYTRVSAYIDWINE 264
P VY RV+ I W+ +
Sbjct: 241 -TTPAVYARVAKLIPWVQK 258
>gi|118498341 chymotrypsin B1 [Homo sapiens]
Length = 263
Score = 189 bits (480), Expect = 2e-48
Identities = 110/259 (42%), Positives = 150/259 (57%), Gaps = 14/259 (5%)
Query: 9 ALLACASSCGVPSFPPNLS--ARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIAS 66
+L+ A CGVP+ P LS +R+V GEDA P SWPWQ+SLQ + T H CGG+LI+
Sbjct: 11 SLVGAAFGCGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQ---DKTGFHFCGGSLISE 67
Query: 67 NFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIK 126
++V+TAAHC RT V V + DEE + + + + +++ L + NDI L+K
Sbjct: 68 DWVVTAAHC--GVRTSDVVVAGEFDQGSDEENIQVLKIAKVFKNPKFSILTVNNDITLLK 125
Query: 127 LAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTN-GPIADKLQQGLQPVVDHAT 185
LA S T+ CLP D P C TGWG+ N DKLQQ P++ +A
Sbjct: 126 LATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKLQQAALPLLSNAE 185
Query: 186 CSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNT 245
C + WG R+ M+CAG GV S+C GDSGGPL CQ ++G+W + GIVS+GS C+T
Sbjct: 186 CKKS--WGRRITDVMICAGASGV-SSCMGDSGGPLVCQ-KDGAWTLVGIVSWGSDT-CST 240
Query: 246 RKKPVVYTRVSAYIDWINE 264
P VY RV+ I W+ +
Sbjct: 241 -SSPGVYARVTKLIPWVQK 258
>gi|4503137 chymotrypsin-like [Homo sapiens]
Length = 264
Score = 180 bits (456), Expect = 1e-45
Identities = 105/267 (39%), Positives = 151/267 (56%), Gaps = 13/267 (4%)
Query: 1 MLGITVLAALLACASSCGVPSFPPNLS--ARVVGGEDARPHSWPWQISLQYLKNDTWRHT 58
+L +T+ LL + CG+P+ P LS R+V GE+A SWPWQ+SLQ + + H
Sbjct: 3 LLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQ---DSSGFHF 59
Query: 59 CGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLL 118
CGG+LI+ ++V+TAAHC + + V +G+ + + E + V H WN+ +
Sbjct: 60 CGGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRS-SNAEPLQVLSVSRAITHPSWNSTTM 118
Query: 119 RNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIAD-KLQQGL 177
ND+ L+KLA + + I CL + L + C TGWGRL G + LQQ
Sbjct: 119 NNDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVA 178
Query: 178 QPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSF 237
P+V C + +WG + +M+CAGG G S+C GDSGGPL CQ N +W + GIVS+
Sbjct: 179 LPLVTVNQCRQ--YWGSSITDSMICAGGAGA-SSCQGDSGGPLVCQKGN-TWVLIGIVSW 234
Query: 238 GSRRGCNTRKKPVVYTRVSAYIDWINE 264
G+ + CN R P VYTRVS + WIN+
Sbjct: 235 GT-KNCNVR-APAVYTRVSKFSTWINQ 259
>gi|110815798 ovochymase 1 [Homo sapiens]
Length = 1134
Score = 167 bits (422), Expect = 1e-41
Identities = 94/258 (36%), Positives = 145/258 (56%), Gaps = 15/258 (5%)
Query: 17 CGVPSFPPN-LSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHC 75
CG+P F P LS R+ GGE+A PH WPWQ+ L++L + + CGG +I ++LTAAHC
Sbjct: 561 CGIPPFSPQWLSRRIAGGEEACPHCWPWQVGLRFLGD----YQCGGAIINPVWILTAAHC 616
Query: 76 I---SNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVE 132
+ +N ++ + G ++ +++ + I VH+ +N L +DIALI+L+ +E
Sbjct: 617 VQLKNNPLSWTIIAGDHDRNLKESTEQVRRAKHII-VHEDFNTLSYDSDIALIQLSSPLE 675
Query: 133 LSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWW 192
+ ++ CLP L C VTGWG + +G +A +LQQ V++ C +
Sbjct: 676 YNSVVRPVCLPHSAEPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYS 735
Query: 193 GF--RVKKTMVCAG--GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKK 248
+ + M+CAG G C GDSGGPL C+ ENG + ++GIVS+G+ GC K
Sbjct: 736 AHPGGITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGA--GCVQPWK 793
Query: 249 PVVYTRVSAYIDWINEKM 266
P V+ RV ++DWI K+
Sbjct: 794 PGVFARVMIFLDWIQSKI 811
Score = 111 bits (278), Expect = 6e-25
Identities = 80/269 (29%), Positives = 131/269 (48%), Gaps = 32/269 (11%)
Query: 20 PSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNT 79
P+ +R+ ++ PWQ+SL K+D H CGG+LI + V+TAAHC+ +
Sbjct: 37 PAVGSRFFSRISSWRNSTVTGHPWQVSL---KSDE-HHFCGGSLIQEDRVVTAAHCLDSL 92
Query: 80 RTYRVAVGKNNLEVEDEEGSLF--------VGVDTIHVHKRWNAL-LLRNDIALIKLAEH 130
++ N+ V E SLF + V I H +N+ + DIAL+ L
Sbjct: 93 SEKQL----KNITVTSGEYSLFQKDKQEQNIPVSKIITHPEYNSREYMSPDIALLYLKHK 148
Query: 131 VELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRI- 189
V+ + +Q CLP+ D + C +GWG++ ++ LQ+ P++D C+ +
Sbjct: 149 VKFGNAVQPICLPDSDDKVEPGILCLSSGWGKISKTSEYSNVLQEMELPIMDDRACNTVL 208
Query: 190 -DWWGFRVKKTMVCAG-GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRK 247
+ +TM+CAG D + AC GDSGGPL C+ G W + GI S+ + GC
Sbjct: 209 KSMNLPPLGRTMLCAGFPDWGMDACQGDSGGPLVCRRGGGIWILAGITSWVA--GCAGGS 266
Query: 248 KPV----------VYTRVSAYIDWINEKM 266
PV ++++VS +D+I + +
Sbjct: 267 VPVRNNHVKASLGIFSKVSELMDFITQNL 295
>gi|4503627 coagulation factor XI precursor [Homo sapiens]
Length = 625
Score = 159 bits (402), Expect = 2e-39
Identities = 94/246 (38%), Positives = 137/246 (55%), Gaps = 10/246 (4%)
Query: 26 LSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHC---ISNTRTY 82
+ R+VGG + WPWQ++L + + T RH CGG++I + ++LTAAHC + + +
Sbjct: 384 IKPRIVGGTASVRGEWPWQVTL-HTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKIL 442
Query: 83 RVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACL 142
RV G N + E +E + F GV I +H ++ DIAL+KL V +D+ + CL
Sbjct: 443 RVYSGILN-QSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYTDSQRPICL 501
Query: 143 PEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVC 202
P K C+VTGWG I + LQ+ P+V + C + + G ++ M+C
Sbjct: 502 PSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQK-RYRGHKITHKMIC 560
Query: 203 AG-GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDW 261
AG +G AC GDSGGPL+C+ N W + GI S+G GC R++P VYT V Y+DW
Sbjct: 561 AGYREGGKDACKGDSGGPLSCK-HNEVWHLVGITSWG--EGCAQRERPGVYTNVVEYVDW 617
Query: 262 INEKMQ 267
I EK Q
Sbjct: 618 ILEKTQ 623
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 157 bits (398), Expect = 7e-39
Identities = 96/245 (39%), Positives = 137/245 (55%), Gaps = 10/245 (4%)
Query: 27 SARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTR---TYR 83
S R+VGG ++ WPWQ+SLQ +K RH CGG+LI +VLTAAHC +R
Sbjct: 388 STRIVGGTNSSWGEWPWQVSLQ-VKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWR 446
Query: 84 VAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLP 143
+ G NL + + + F + I +H+ + +DIALIKL + ++ + CLP
Sbjct: 447 IYSGILNLS-DITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLP 505
Query: 144 EKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCA 203
K C+VTGWG G I + LQ+ P+V + C + + +++ + MVCA
Sbjct: 506 SKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQK-RYQDYKITQRMVCA 564
Query: 204 G-GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWI 262
G +G AC GDSGGPL C+ NG W + GI S+G GC R++P VYT+V+ Y+DWI
Sbjct: 565 GYKEGGKDACKGDSGGPLVCK-HNGMWRLVGITSWG--EGCARREQPGVYTKVAEYMDWI 621
Query: 263 NEKMQ 267
EK Q
Sbjct: 622 LEKTQ 626
>gi|33695155 hepsin [Homo sapiens]
Length = 417
Score = 154 bits (388), Expect = 1e-37
Identities = 98/270 (36%), Positives = 138/270 (51%), Gaps = 32/270 (11%)
Query: 10 LLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFV 69
L A CG P + R+VGG D WPWQ+SL+Y H CGG+L++ ++V
Sbjct: 146 LAAICQDCGRRKLPVD---RIVGGRDTSLGRWPWQVSLRY----DGAHLCGGSLLSGDWV 198
Query: 70 LTAAHC-------ISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRW------NAL 116
LTAAHC +S R + AV + + L +GV + H + N+
Sbjct: 199 LTAAHCFPERNRVLSRWRVFAGAVAQASPH------GLQLGVQAVVYHGGYLPFRDPNSE 252
Query: 117 LLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQG 176
NDIAL+ L+ + L++ IQ CLP L C VTGWG G A LQ+
Sbjct: 253 ENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEA 312
Query: 177 LQPVVDHATCSRIDWWGFRVKKTMVCAG-GDGVISACNGDSGGPLNCQ---LENGSWEVF 232
P++ + C+ D++G ++K M CAG +G I AC GDSGGP C+ W +
Sbjct: 313 RVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLC 372
Query: 233 GIVSFGSRRGCNTRKKPVVYTRVSAYIDWI 262
GIVS+G+ GC +KP VYT+VS + +WI
Sbjct: 373 GIVSWGT--GCALAQKPGVYTKVSDFREWI 400
>gi|4504481 hepsin [Homo sapiens]
Length = 417
Score = 154 bits (388), Expect = 1e-37
Identities = 98/270 (36%), Positives = 138/270 (51%), Gaps = 32/270 (11%)
Query: 10 LLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFV 69
L A CG P + R+VGG D WPWQ+SL+Y H CGG+L++ ++V
Sbjct: 146 LAAICQDCGRRKLPVD---RIVGGRDTSLGRWPWQVSLRY----DGAHLCGGSLLSGDWV 198
Query: 70 LTAAHC-------ISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRW------NAL 116
LTAAHC +S R + AV + + L +GV + H + N+
Sbjct: 199 LTAAHCFPERNRVLSRWRVFAGAVAQASPH------GLQLGVQAVVYHGGYLPFRDPNSE 252
Query: 117 LLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQG 176
NDIAL+ L+ + L++ IQ CLP L C VTGWG G A LQ+
Sbjct: 253 ENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEA 312
Query: 177 LQPVVDHATCSRIDWWGFRVKKTMVCAG-GDGVISACNGDSGGPLNCQ---LENGSWEVF 232
P++ + C+ D++G ++K M CAG +G I AC GDSGGP C+ W +
Sbjct: 313 RVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLC 372
Query: 233 GIVSFGSRRGCNTRKKPVVYTRVSAYIDWI 262
GIVS+G+ GC +KP VYT+VS + +WI
Sbjct: 373 GIVSWGT--GCALAQKPGVYTKVSDFREWI 400
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 154 bits (388), Expect = 1e-37
Identities = 89/246 (36%), Positives = 135/246 (54%), Gaps = 15/246 (6%)
Query: 27 SARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNT---RTYR 83
S+R+VGG + WPWQ SLQ+ H CGG++I +++TAAHC+ + +++
Sbjct: 214 SSRIVGGNMSLLSQWPWQASLQF----QGYHLCGGSVITPLWIITAAHCVYDLYLPKSWT 269
Query: 84 VAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLP 143
+ VG +L L V+ I H ++ L NDIAL+KLA + ++ IQ CLP
Sbjct: 270 IQVGLVSLLDNPAPSHL---VEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVCLP 326
Query: 144 EKDSLLPKDYPCYVTGWGRLWTN-GPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVC 202
+ P C+ +GWG G + L P++ + C+ D +G + +M+C
Sbjct: 327 NSEENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLC 386
Query: 203 AGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDW 261
AG G + +C GDSGGPL CQ E W++ G SFG GC KP VYTRV++++DW
Sbjct: 387 AGYLTGGVDSCQGDSGGPLVCQ-ERRLWKLVGATSFGI--GCAEVNKPGVYTRVTSFLDW 443
Query: 262 INEKMQ 267
I+E+M+
Sbjct: 444 IHEQME 449
>gi|4505881 plasminogen [Homo sapiens]
Length = 810
Score = 153 bits (387), Expect = 1e-37
Identities = 98/257 (38%), Positives = 140/257 (54%), Gaps = 21/257 (8%)
Query: 17 CGVPSFPPN-LSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHC 75
CG P P RVVGG A PHSWPWQ+SL + H CGGTLI+ +VLTAAHC
Sbjct: 567 CGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSL---RTRFGMHFCGGTLISPEWVLTAAHC 623
Query: 76 ISNT---RTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVE 132
+ + +Y+V +G + +E +L V I V + + R DIAL+KL+
Sbjct: 624 LEKSPRPSSYKVILGAH------QEVNLEPHVQEIEVSRLFLEPT-RKDIALLKLSSPAV 676
Query: 133 LSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPI-ADKLQQGLQPVVDHATCSRIDW 191
++D + ACLP + ++ C++TGWG T G A L++ PV+++ C+R ++
Sbjct: 677 ITDKVIPACLPSPNYVVADRTECFITGWGE--TQGTFGAGLLKEAQLPVIENKVCNRYEF 734
Query: 192 WGFRVKKTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPV 250
RV+ T +CAG G +C GDSGGPL C E + + G+ S+G GC KP
Sbjct: 735 LNGRVQSTELCAGHLAGGTDSCQGDSGGPLVC-FEKDKYILQGVTSWG--LGCARPNKPG 791
Query: 251 VYTRVSAYIDWINEKMQ 267
VY RVS ++ WI M+
Sbjct: 792 VYVRVSRFVTWIEGVMR 808
>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
Length = 457
Score = 153 bits (387), Expect = 1e-37
Identities = 93/261 (35%), Positives = 142/261 (54%), Gaps = 22/261 (8%)
Query: 15 SSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAH 74
S CG L++R+VGG+ P WPWQ S+ +RHTCGG+++A +V+TAAH
Sbjct: 207 SECGARP----LASRIVGGQSVAPGRWPWQASVAL----GFRHTCGGSVLAPRWVVTAAH 258
Query: 75 CISNTR-----TYRVAVGK-NNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLA 128
C+ + R ++RV G ++ V +G+L V+ I H ++A D+AL++L
Sbjct: 259 CMHSFRLARLSSWRVHAGLVSHSAVRPHQGAL---VERIIPHPLYSAQNHDYDVALLRLQ 315
Query: 129 EHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPI-ADKLQQGLQPVVDHATCS 187
+ SDT+ CLP K+ PK C+V+GWG + +D LQ + P+ C+
Sbjct: 316 TALNFSDTVGAVCLPAKEQHFPKGSRCWVSGWGHTHPSHTYSSDMLQDTVVPLFSTQLCN 375
Query: 188 RIDWWGFRVKKTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTR 246
+ + M+CAG DG AC GDSGGPL C + +W + G+VS+G RGC
Sbjct: 376 SSCVYSGALTPRMLCAGYLDGRADACQGDSGGPLVCP-DGDTWRLVGVVSWG--RGCAEP 432
Query: 247 KKPVVYTRVSAYIDWINEKMQ 267
P VY +V+ ++DWI++ Q
Sbjct: 433 NHPGVYAKVAEFLDWIHDTAQ 453
>gi|29244926 corin [Homo sapiens]
Length = 1042
Score = 152 bits (385), Expect = 2e-37
Identities = 92/269 (34%), Positives = 147/269 (54%), Gaps = 23/269 (8%)
Query: 9 ALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNF 68
+LL CG ++ R++GG +RP WPWQ SLQ ++ H CG LIA +
Sbjct: 782 SLLCTKQDCGRRP-AARMNKRILGGRTSRPGRWPWQCSLQ---SEPSGHICGCVLIAKKW 837
Query: 69 VLTAAHCIS---NTRTYRVAVGKNNLEVEDEEGSLFVG---VDTIHVHKRWNALLLRNDI 122
VLT AHC N ++V +G NNL+ S+F+ V TI +H R++ ++ DI
Sbjct: 838 VLTVAHCFEGRENAAVWKVVLGINNLD----HPSVFMQTRFVKTIILHPRYSRAVVDYDI 893
Query: 123 ALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVD 182
++++L+E + + ++ CLP + L D CY+TGWG + P KLQ+G ++
Sbjct: 894 SIVELSEDISETGYVRPVCLPNPEQWLEPDTYCYITGWGHMGNKMPF--KLQEGEVRIIS 951
Query: 183 HATCSRIDWWGFRVKKT-MVCAGGD-GVISACNGDSGGPLNCQLENGSWEVFGIVSFGSR 240
C ++ + T M+CAG + G + +C GDSGGPL C+ G W +FG+ S+GS
Sbjct: 952 LEHCQ--SYFDMKTITTRMICAGYESGTVDSCMGDSGGPLVCEKPGGRWTLFGLTSWGS- 1008
Query: 241 RGCNTR-KKPVVYTRVSAYIDWINEKMQL 268
C ++ P VY+ VS +++WI ++ +
Sbjct: 1009 -VCFSKVLGPGVYSNVSYFVEWIKRQIYI 1036
>gi|117956391 protease, serine, 33 [Homo sapiens]
Length = 280
Score = 152 bits (385), Expect = 2e-37
Identities = 100/266 (37%), Positives = 138/266 (51%), Gaps = 25/266 (9%)
Query: 14 ASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAA 73
+++CG P +S+R+VGG D R WPWQ S+Q+ H CGG+LIA +VLTAA
Sbjct: 25 SAACG----QPRMSSRIVGGRDGRDGEWPWQASIQH----RGAHVCGGSLIAPQWVLTAA 76
Query: 74 HCISNTRT---YRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEH 130
HC YRV +G L +L V V + + ++ R D+AL++L
Sbjct: 77 HCFPRRALPAEYRVRLGALRLGSTSPR-TLSVPVRRVLLPPDYSEDGARGDLALLQLRRP 135
Query: 131 VELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIAD--KLQQGLQPVVDHATCSR 188
V LS +Q CLP + P PC VTGWG L P+ + LQ P++D TC
Sbjct: 136 VPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDG 195
Query: 189 IDWWGFRVKKT-------MVCAG-GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSR 240
+ G V + +CAG G AC GDSGGPL C L++GSW + G+VS+G
Sbjct: 196 LYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTC-LQSGSWVLVGVVSWG-- 252
Query: 241 RGCNTRKKPVVYTRVSAYIDWINEKM 266
+GC +P VYT V+ Y WI ++
Sbjct: 253 KGCALPNRPGVYTSVATYSPWIQARV 278
>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
Length = 418
Score = 150 bits (380), Expect = 9e-37
Identities = 92/264 (34%), Positives = 134/264 (50%), Gaps = 10/264 (3%)
Query: 4 ITVLAALLACASSCGV-PSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGT 62
+T AA + CG P R++GG +A SWPWQ+SL+ L N H CGG+
Sbjct: 160 LTDQAAANWLINECGAGPDLITLSEQRILGGTEAEEGSWPWQVSLR-LNN---AHHCGGS 215
Query: 63 LIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDI 122
LI + ++LTAAHC + R + + + + L + V I +H + + NDI
Sbjct: 216 LINNMWILTAAHCFRSNSNPRDWIATSGISTTFPK--LRMRVRNILIHNNYKSATHENDI 273
Query: 123 ALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVD 182
AL++L V + I CLP +P YVTGWG G +L+QG ++
Sbjct: 274 ALVRLENSVTFTKDIHSVCLPAATQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIIS 333
Query: 183 HATCSRIDWWGFRVKKTMVCAG-GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRR 241
+ C+ + + M+CAG G + AC GDSGGPL + W + GIVS+G +
Sbjct: 334 NDVCNAPHSYNGAILSGMLCAGVPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQ- 392
Query: 242 GCNTRKKPVVYTRVSAYIDWINEK 265
C KP VYTRV+AY+DWI ++
Sbjct: 393 -CGLPDKPGVYTRVTAYLDWIRQQ 415
>gi|187761337 transmembrane protease, serine 11B [Homo sapiens]
Length = 416
Score = 149 bits (377), Expect = 2e-36
Identities = 88/244 (36%), Positives = 133/244 (54%), Gaps = 15/244 (6%)
Query: 29 RVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCIS---NTRTYRVA 85
++V G+ + +WPWQ S+Q+ RH CG +LI+S ++L+AAHC + N++ + V
Sbjct: 184 KIVNGKSSLEGAWPWQASMQW----KGRHYCGASLISSRWLLSAAHCFAKKNNSKDWTV- 238
Query: 86 VGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEK 145
N + + + V I H+ +++ L +DIAL++LAE V ++ I+ CLPE
Sbjct: 239 ----NFGIVVNKPYMTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPEA 294
Query: 146 DSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAG- 204
L ++ VTGWG L+ NG LQ+ ++D+ C+ + V TM+CAG
Sbjct: 295 KMKLSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAYSGFVTDTMLCAGF 354
Query: 205 GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINE 264
G AC DSGGPL W + GIVS+G GC + KP VYTRV++Y +WI
Sbjct: 355 MSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGD--GCGKKNKPGVYTRVTSYRNWITS 412
Query: 265 KMQL 268
K L
Sbjct: 413 KTGL 416
>gi|148613878 acrosin precursor [Homo sapiens]
Length = 421
Score = 149 bits (377), Expect = 2e-36
Identities = 98/282 (34%), Positives = 148/282 (52%), Gaps = 20/282 (7%)
Query: 1 MLGITVLAALLA-CASSCGVPSFP-PNLSARVVGGEDARPHSWPWQISLQYLKNDTWR-H 57
+L ++V+A A C CG+ P R+VGG+ A+ +WPW +SLQ ++ R H
Sbjct: 12 VLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSLQIFTYNSHRYH 71
Query: 58 TCGGTLIASNFVLTAAHCI---SNTRTYRVAVGK------NNLEVEDEEGSLFVGVDTIH 108
TCGG+L+ S +VLTAAHC +N +R+ G NN V+ + V+ I
Sbjct: 72 TCGGSLLNSRWVLTAAHCFVGKNNVHDWRLVFGAKEITYGNNKPVKAPLQERY--VEKII 129
Query: 109 VHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPK-DYPCYVTGWGRLWTNG 167
+H+++N+ NDIAL+++ + I CLP + LP+ C+V GWG +
Sbjct: 130 IHEKYNSATEGNDIALVEITPPISCGRFIGPGCLPHFKAGLPRGSQSCWVAGWGYIEEKA 189
Query: 168 PIADK-LQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGD-GVISACNGDSGGPLNCQ-L 224
P L + ++D C+ W+ RV+ T VCAG G I C GDSGGPL C+
Sbjct: 190 PRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDS 249
Query: 225 ENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKM 266
+ ++ V GI S+G GC K+P +YT Y++WI K+
Sbjct: 250 KESAYVVVGITSWGV--GCARAKRPGIYTATWPYLNWIASKI 289
>gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo
sapiens]
Length = 432
Score = 149 bits (375), Expect = 3e-36
Identities = 101/266 (37%), Positives = 139/266 (52%), Gaps = 28/266 (10%)
Query: 3 GITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGT 62
G V LAC S P RVVGGE+A SWPWQ+S+QY K +H CGG+
Sbjct: 181 GSLVSLHCLACGKSLKTP--------RVVGGEEASVDSWPWQVSIQYDK----QHVCGGS 228
Query: 63 LIASNFVLTAAHCI---SNTRTYRVAVGKNNLEVEDEEGSL-FVGVDTIHVHKRWNALLL 118
++ ++VLTAAHC ++ ++V G + L GS + V I + +
Sbjct: 229 ILDPHWVLTAAHCFRKHTDVFNWKVRAGSDKL------GSFPSLAVAKIIIIEFNPMYPK 282
Query: 119 RNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTN-GPIADKLQQGL 177
NDIAL+KL + S T++ CLP D L P ++ GWG N G ++D L Q
Sbjct: 283 DNDIALMKLQFPLTFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQAS 342
Query: 178 QPVVDHATCSRIDWWGFRVKKTMVCAG-GDGVISACNGDSGGPLNCQLENGSWEVFGIVS 236
V+D C+ D + V + M+CAG +G + C GDSGGPL ++ W V GIVS
Sbjct: 343 VQVIDSTRCNADDAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPL--MYQSDQWHVVGIVS 400
Query: 237 FGSRRGCNTRKKPVVYTRVSAYIDWI 262
+G GC P VYT+VSAY++WI
Sbjct: 401 WG--YGCGGPSTPGVYTKVSAYLNWI 424
>gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo
sapiens]
Length = 437
Score = 149 bits (375), Expect = 3e-36
Identities = 101/266 (37%), Positives = 139/266 (52%), Gaps = 28/266 (10%)
Query: 3 GITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGT 62
G V LAC S P RVVGGE+A SWPWQ+S+QY K +H CGG+
Sbjct: 186 GSLVSLHCLACGKSLKTP--------RVVGGEEASVDSWPWQVSIQYDK----QHVCGGS 233
Query: 63 LIASNFVLTAAHCI---SNTRTYRVAVGKNNLEVEDEEGSL-FVGVDTIHVHKRWNALLL 118
++ ++VLTAAHC ++ ++V G + L GS + V I + +
Sbjct: 234 ILDPHWVLTAAHCFRKHTDVFNWKVRAGSDKL------GSFPSLAVAKIIIIEFNPMYPK 287
Query: 119 RNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTN-GPIADKLQQGL 177
NDIAL+KL + S T++ CLP D L P ++ GWG N G ++D L Q
Sbjct: 288 DNDIALMKLQFPLTFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQAS 347
Query: 178 QPVVDHATCSRIDWWGFRVKKTMVCAG-GDGVISACNGDSGGPLNCQLENGSWEVFGIVS 236
V+D C+ D + V + M+CAG +G + C GDSGGPL ++ W V GIVS
Sbjct: 348 VQVIDSTRCNADDAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPL--MYQSDQWHVVGIVS 405
Query: 237 FGSRRGCNTRKKPVVYTRVSAYIDWI 262
+G GC P VYT+VSAY++WI
Sbjct: 406 WG--YGCGGPSTPGVYTKVSAYLNWI 429
>gi|68508970 tryptase beta 2 precursor [Homo sapiens]
Length = 275
Score = 147 bits (370), Expect = 1e-35
Identities = 96/278 (34%), Positives = 147/278 (52%), Gaps = 25/278 (8%)
Query: 1 MLGITVLAALLACASSCGVPSFPPNLSARV--VGGEDARPHSWPWQISLQYLKNDTWRHT 58
ML + +LA + + + P+ P RV VGG++A WPWQ+SL+ +++ W H
Sbjct: 1 MLNLLLLALPVLASRAYAAPA-PGQALQRVGIVGGQEAPRSKWPWQVSLR-VRDRYWMHF 58
Query: 59 CGGTLIASNFVLTAAHCIS----NTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWN 114
CGG+LI +VLTAAHC+ + RV + + +L +D+ + V I VH ++
Sbjct: 59 CGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQ----LLPVSRIIVHPQFY 114
Query: 115 ALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNG--PIADK 172
+ DIAL++L E V +S + LP P PC+VTGWG + + P
Sbjct: 115 TAQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFP 174
Query: 173 LQQGLQPVVDHATCSRIDWWGFR-------VKKTMVCAGGDGVISACNGDSGGPLNCQLE 225
L+Q P++++ C G V+ M+CAG +C GDSGGPL C++
Sbjct: 175 LKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTR-RDSCQGDSGGPLVCKV- 232
Query: 226 NGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWIN 263
NG+W G+VS+G GC +P +YTRV+ Y+DWI+
Sbjct: 233 NGTWLQAGVVSWG--EGCAQPNRPGIYTRVTYYLDWIH 268
>gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]
Length = 275
Score = 145 bits (367), Expect = 3e-35
Identities = 96/278 (34%), Positives = 145/278 (52%), Gaps = 25/278 (8%)
Query: 1 MLGITVLAALLACASSCGVPSFPPNLSARV--VGGEDARPHSWPWQISLQYLKNDTWRHT 58
ML + +LA + + + P+ P RV VGG++A WPWQ+SL+ + W H
Sbjct: 1 MLNLLLLALPVLASRAYAAPA-PGQALQRVGIVGGQEAPRSKWPWQVSLR-VHGPYWMHF 58
Query: 59 CGGTLIASNFVLTAAHCIS----NTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWN 114
CGG+LI +VLTAAHC+ + RV + + +L +D+ + V I VH ++
Sbjct: 59 CGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQ----LLPVSRIIVHPQFY 114
Query: 115 ALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNG--PIADK 172
+ DIAL++L E V +S + LP P PC+VTGWG + + P
Sbjct: 115 TAQIGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFP 174
Query: 173 LQQGLQPVVDHATCSRIDWWGFR-------VKKTMVCAGGDGVISACNGDSGGPLNCQLE 225
L+Q P++++ C G V+ M+CAG +C GDSGGPL C++
Sbjct: 175 LKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTR-RDSCQGDSGGPLVCKV- 232
Query: 226 NGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWIN 263
NG+W G+VS+G GC +P +YTRV+ Y+DWI+
Sbjct: 233 NGTWLQAGVVSWG--EGCAQPNRPGIYTRVTYYLDWIH 268
>gi|11545839 protease, serine, 22 [Homo sapiens]
Length = 317
Score = 145 bits (367), Expect = 3e-35
Identities = 96/272 (35%), Positives = 142/272 (52%), Gaps = 25/272 (9%)
Query: 8 AALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASN 67
AA + +CG P RVVGGED+ WPW +S+Q KN T H C G+L+ S
Sbjct: 32 AARIPVPPACG----KPQQLNRVVGGEDSTDSEWPWIVSIQ--KNGT--HHCAGSLLTSR 83
Query: 68 FVLTAAHCISNTRT----YRVAVGKNNLEVEDEEGSLFVGVDTIHVHK--RWNALLLRND 121
+V+TAAHC + + V +G L S VGV + H W D
Sbjct: 84 WVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSR-SQKVGVAWVEPHPVYSWKEGACA-D 141
Query: 122 IALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPI--ADKLQQGLQP 179
IAL++L ++ S+ + CLP+ LP + C+++GWG + P+ LQ+ P
Sbjct: 142 IALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLKVP 201
Query: 180 VVDHATCSRIDWWGF---RVKKTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIV 235
++D CS + W G + + M+CAG +G AC GDSGGPL CQ++ G+W + GI+
Sbjct: 202 IIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGERDACLGDSGGPLMCQVD-GAWLLAGII 260
Query: 236 SFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267
S+G GC R +P VY +SA+ W+ + +Q
Sbjct: 261 SWG--EGCAERNRPGVYISLSAHRSWVEKIVQ 290
>gi|223942069 enterokinase precursor [Homo sapiens]
Length = 1019
Score = 144 bits (363), Expect = 8e-35
Identities = 85/255 (33%), Positives = 136/255 (53%), Gaps = 19/255 (7%)
Query: 16 SCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHC 75
SCG +++ ++VGG +A+ +WPW + L Y R CG +L++S+++++AAHC
Sbjct: 771 SCGKKLAAQDITPKIVGGSNAKEGAWPWVVGLYY----GGRLLCGASLVSSDWLVSAAHC 826
Query: 76 ISNTRT----YRVAVG---KNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLA 128
+ + +G K+NL L +D I ++ +N NDIA++ L
Sbjct: 827 VYGRNLEPSKWTAILGLHMKSNLTSPQTVPRL---IDEIVINPHYNRRRKDNDIAMMHLE 883
Query: 129 EHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSR 188
V +D IQ CLPE++ + P C + GWG + G A+ LQ+ P++ + C +
Sbjct: 884 FKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQ 943
Query: 189 IDWWGFRVKKTMVCAG-GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRK 247
+ + + M+CAG +G I +C GDSGGPL CQ EN W + G+ SFG + C
Sbjct: 944 -QMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQ-ENNRWFLAGVTSFGYK--CALPN 999
Query: 248 KPVVYTRVSAYIDWI 262
+P VY RVS + +WI
Sbjct: 1000 RPGVYARVSRFTEWI 1014
>gi|194018492 transmembrane protease, serine 11F [Homo sapiens]
Length = 438
Score = 143 bits (360), Expect = 2e-34
Identities = 92/260 (35%), Positives = 135/260 (51%), Gaps = 17/260 (6%)
Query: 15 SSCGVPSFPPNL-------SARVVGG-EDARPHSWPWQISLQYLKNDTWRHTCGGTLIAS 66
S CG+ N+ + R+V G E A WPWQ SLQ + + H CG +LI++
Sbjct: 184 SRCGIRMTSSNMPLPASSSTQRIVQGRETAMEGEWPWQASLQLIGSG---HQCGASLISN 240
Query: 67 NFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIK 126
++LTAAHC + + + ++ V I +H+ ++ NDIAL++
Sbjct: 241 TWLLTAAHCFWKNKDPTQWIATFGATITPP--AVKRNVRKIILHENYHRETNENDIALVQ 298
Query: 127 LAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATC 186
L+ VE S+ +Q CLP+ LP +VTG+G + +GPI + L+Q + C
Sbjct: 299 LSTGVEFSNIVQRVCLPDSSIKLPPKTSVFVTGFGSIVDDGPIQNTLRQARVETISTDVC 358
Query: 187 SRIDWWGFRVKKTMVCAG-GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNT 245
+R D + + M+CAG +G I AC GDSGGPL + W + GIVS+G + C
Sbjct: 359 NRKDVYDGLITPGMLCAGFMEGKIDACKGDSGGPLVYD-NHDIWYIVGIVSWG--QSCAL 415
Query: 246 RKKPVVYTRVSAYIDWINEK 265
KKP VYTRV+ Y DWI K
Sbjct: 416 PKKPGVYTRVTKYRDWIASK 435
>gi|13994276 marapsin [Homo sapiens]
Length = 290
Score = 142 bits (359), Expect = 2e-34
Identities = 92/263 (34%), Positives = 142/263 (53%), Gaps = 25/263 (9%)
Query: 14 ASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAA 73
A++CG P + R+VGG+D + WPWQ+S+Q +N + H CGG+LIA +VLTAA
Sbjct: 23 ATACG----RPRMLNRMVGGQDTQEGEWPWQVSIQ--RNGS--HFCGGSLIAEQWVLTAA 74
Query: 74 HCISN---TRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEH 130
HC N T Y+V +G L V+ +++ V + + + D+AL++L
Sbjct: 75 HCFRNTSETSLYQVLLGARQL-VQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAP 133
Query: 131 VELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADK--LQQGLQPVVDHATC-- 186
V ++ I CLP+ + C+VTGWG + + LQ+ P++D C
Sbjct: 134 VPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNL 193
Query: 187 --SRIDWWGFR---VKKTMVCAG-GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSR 240
S+ +G++ +K M+CAG +G AC GDSGGPL C L SW G++S+G
Sbjct: 194 LYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVC-LVGQSWLQAGVISWG-- 250
Query: 241 RGCNTRKKPVVYTRVSAYIDWIN 263
GC + +P VY RV+A+ +WI+
Sbjct: 251 EGCARQNRPGVYIRVTAHHNWIH 273
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.450
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,292,668
Number of Sequences: 37866
Number of extensions: 514740
Number of successful extensions: 1679
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 167
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 902
Number of HSP's gapped (non-prelim): 210
length of query: 268
length of database: 18,247,518
effective HSP length: 100
effective length of query: 168
effective length of database: 14,460,918
effective search space: 2429434224
effective search space used: 2429434224
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.