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Search of human proteins with 62388868
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62388868 F-box protein 44 isoform 1 [Homo sapiens]
(255 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|34878735 F-box protein 44 isoform 1 [Homo sapiens] 552 e-157
gi|62388868 F-box protein 44 isoform 1 [Homo sapiens] 552 e-157
gi|8922188 F-box only protein 6 [Homo sapiens] 405 e-113
gi|34878749 F-box protein 44 isoform 2 [Homo sapiens] 264 5e-71
gi|34878753 F-box protein 44 isoform 2 [Homo sapiens] 264 5e-71
gi|15812198 F-box only protein 2 [Homo sapiens] 256 1e-68
gi|30520327 F-box protein 27 [Homo sapiens] 177 1e-44
gi|22325388 F-box protein FBG4 isoform 1 [Homo sapiens] 163 2e-40
gi|18643385 F-box protein FBG4 isoform 2 [Homo sapiens] 163 2e-40
gi|47825361 non-specific cytotoxic cell receptor protein 1 homol... 85 5e-17
gi|30795117 F-box only protein, helicase, 18 isoform 1 [Homo sap... 39 0.003
gi|30795119 F-box only protein, helicase, 18 isoform 2 [Homo sap... 39 0.003
gi|8923179 F-box and leucine-rich repeat protein 12 [Homo sapiens] 39 0.006
gi|83035136 F-box protein 31 [Homo sapiens] 37 0.022
gi|27312027 F-box only protein 16 [Homo sapiens] 36 0.029
gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [H... 34 0.11
gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [H... 34 0.11
gi|118402584 F-box and WD repeat domain containing 2 [Homo sapiens] 34 0.14
gi|124248558 F-box and WD-40 domain protein 9 [Homo sapiens] 32 0.54
gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [H... 31 0.92
gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [H... 31 0.92
gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [H... 31 0.92
gi|236463969 neuregulin 1 isoform HRG-beta3b [Homo sapiens] 31 1.2
gi|236462773 neuregulin 1 isoform HRG-beta1d [Homo sapiens] 31 1.2
gi|236462348 neuregulin 1 isoform HRG-beta1b [Homo sapiens] 31 1.2
gi|236461509 neuregulin 1 isoform HRG-beta1c [Homo sapiens] 31 1.2
gi|116006959 neuregulin 1 isoform HRG-beta3 [Homo sapiens] 31 1.2
gi|116006955 neuregulin 1 isoform HRG-beta1 [Homo sapiens] 31 1.2
gi|7669518 neuregulin 1 isoform SMDF [Homo sapiens] 31 1.2
gi|116006967 neuregulin 1 isoform GGF2 [Homo sapiens] 31 1.2
>gi|34878735 F-box protein 44 isoform 1 [Homo sapiens]
Length = 255
Score = 552 bits (1422), Expect = e-157
Identities = 255/255 (100%), Positives = 255/255 (100%)
Query: 1 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 60
MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED
Sbjct: 1 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 60
Query: 61 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 120
WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND
Sbjct: 61 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 120
Query: 121 QVKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQL 180
QVKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQL
Sbjct: 121 QVKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQL 180
Query: 181 LSSAHAPLGTFQPDPATIQQKSDAKWREVSHTFSNYPPGVRYIWFQHGGVDTHYWAGWYG 240
LSSAHAPLGTFQPDPATIQQKSDAKWREVSHTFSNYPPGVRYIWFQHGGVDTHYWAGWYG
Sbjct: 181 LSSAHAPLGTFQPDPATIQQKSDAKWREVSHTFSNYPPGVRYIWFQHGGVDTHYWAGWYG 240
Query: 241 PRVTNSSITIGPPLP 255
PRVTNSSITIGPPLP
Sbjct: 241 PRVTNSSITIGPPLP 255
>gi|62388868 F-box protein 44 isoform 1 [Homo sapiens]
Length = 255
Score = 552 bits (1422), Expect = e-157
Identities = 255/255 (100%), Positives = 255/255 (100%)
Query: 1 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 60
MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED
Sbjct: 1 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 60
Query: 61 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 120
WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND
Sbjct: 61 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 120
Query: 121 QVKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQL 180
QVKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQL
Sbjct: 121 QVKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQL 180
Query: 181 LSSAHAPLGTFQPDPATIQQKSDAKWREVSHTFSNYPPGVRYIWFQHGGVDTHYWAGWYG 240
LSSAHAPLGTFQPDPATIQQKSDAKWREVSHTFSNYPPGVRYIWFQHGGVDTHYWAGWYG
Sbjct: 181 LSSAHAPLGTFQPDPATIQQKSDAKWREVSHTFSNYPPGVRYIWFQHGGVDTHYWAGWYG 240
Query: 241 PRVTNSSITIGPPLP 255
PRVTNSSITIGPPLP
Sbjct: 241 PRVTNSSITIGPPLP 255
>gi|8922188 F-box only protein 6 [Homo sapiens]
Length = 293
Score = 405 bits (1042), Expect = e-113
Identities = 190/253 (75%), Positives = 210/253 (83%)
Query: 2 AVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITEDW 61
A+ +INELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDL+TLWKRKCLREGFIT+DW
Sbjct: 9 ALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLREGFITKDW 68
Query: 62 DQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPNDQ 121
DQPVADWKIFYFLRSLHRNLL NPCAEE W +D NGGD WKVE L +FP+ +
Sbjct: 69 DQPVADWKIFYFLRSLHRNLLRNPCAEEDMFAWQIDFNGGDRWKVESLPGAHGTDFPDPK 128
Query: 122 VKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQLL 181
VKKYFVTSY CLKSQ+VDL AEGYWEEL+DT RPDI VKDWFAAR DCG YQL VQL
Sbjct: 129 VKKYFVTSYEMCLKSQLVDLVAEGYWEELLDTFRPDIVVKDWFAARADCGCTYQLKVQLA 188
Query: 182 SSAHAPLGTFQPDPATIQQKSDAKWREVSHTFSNYPPGVRYIWFQHGGVDTHYWAGWYGP 241
S+ + L +F+P P TIQQ ++A W EVS+TFS+YP GVRYI FQHGG DT YWAGWYGP
Sbjct: 189 SADYFVLASFEPPPVTIQQWNNATWTEVSYTFSDYPRGVRYILFQHGGRDTQYWAGWYGP 248
Query: 242 RVTNSSITIGPPL 254
RVTNSSI + P +
Sbjct: 249 RVTNSSIVVSPKM 261
>gi|34878749 F-box protein 44 isoform 2 [Homo sapiens]
Length = 224
Score = 264 bits (675), Expect = 5e-71
Identities = 122/123 (99%), Positives = 123/123 (100%)
Query: 1 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 60
MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED
Sbjct: 1 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 60
Query: 61 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 120
WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND
Sbjct: 61 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 120
Query: 121 QVK 123
QV+
Sbjct: 121 QVR 123
>gi|34878753 F-box protein 44 isoform 2 [Homo sapiens]
Length = 224
Score = 264 bits (675), Expect = 5e-71
Identities = 122/123 (99%), Positives = 123/123 (100%)
Query: 1 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 60
MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED
Sbjct: 1 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 60
Query: 61 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 120
WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND
Sbjct: 61 WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 120
Query: 121 QVK 123
QV+
Sbjct: 121 QVR 123
>gi|15812198 F-box only protein 2 [Homo sapiens]
Length = 296
Score = 256 bits (654), Expect = 1e-68
Identities = 124/254 (48%), Positives = 165/254 (64%), Gaps = 3/254 (1%)
Query: 2 AVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITEDW 61
A ++ELPE +LL + +PA +L+ CRLVC W++L+D LW KC +EG + E
Sbjct: 43 AAAYLDELPEPLLLRVLAALPAAELVQACRLVCLRWKELVDGAPLWLLKCQQEGLVPEGG 102
Query: 62 DQPVAD-WKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 120
+ D W+ FYFL RNLL NPC EE E W +GGD W+VE+L D EF +D
Sbjct: 103 VEEERDHWQQFYFLSKRRRNLLRNPCGEEDLEGWCDVEHGGDGWRVEELPGDSGVEFTHD 162
Query: 121 Q-VKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQ 179
+ VKKYF +S+ C K+QV+DL+AEGYWEEL+DTT+P I VKDW++ R D G Y+L V+
Sbjct: 163 ESVKKYFASSFEWCRKAQVIDLQAEGYWEELLDTTQPAIVVKDWYSGRSDAGCLYELTVK 222
Query: 180 LLSSAHAPLGTFQPDPATIQQKSD-AKWREVSHTFSNYPPGVRYIWFQHGGVDTHYWAGW 238
LLS L F + Q SD W E+SHTF++Y PGVR++ F+HGG D+ YW GW
Sbjct: 223 LLSEHENVLAEFSSGQVAVPQDSDGGGWMEISHTFTDYGPGVRFVRFEHGGQDSVYWKGW 282
Query: 239 YGPRVTNSSITIGP 252
+G RVTNSS+ + P
Sbjct: 283 FGARVTNSSVWVEP 296
>gi|30520327 F-box protein 27 [Homo sapiens]
Length = 283
Score = 177 bits (448), Expect = 1e-44
Identities = 102/259 (39%), Positives = 138/259 (53%), Gaps = 18/259 (6%)
Query: 5 NINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFIT------ 58
++++LP +LL + +HVP R LL CR VC WR L+D LW R+ T
Sbjct: 25 DLSQLPPELLLVVLSHVPPRTLLGRCRQVCRGWRALVDGQALWLLILARDHGATGRALLH 84
Query: 59 --EDWDQPVADWKI-----FYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSR 111
P + + F R + RNL+ NPC +EG W + +GGD W VE+
Sbjct: 85 LARSCQSPARNARPCPLGRFCARRPIGRNLIRNPCGQEGLRKWMVQ-HGGDGWVVEE--- 140
Query: 112 DQRKEFPNDQVKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCG 171
R P + FVTS+ C K QV+DL+ EG W EL+D+ R +I V DW+ AR D G
Sbjct: 141 -NRTTVPGAPSQTCFVTSFSWCCKKQVLDLEEEGLWPELLDSGRIEICVSDWWGARHDSG 199
Query: 172 SKYQLCVQLLSSAHAPLGTFQPDPATIQQKSDAKWREVSHTFSNYPPGVRYIWFQHGGVD 231
Y+L VQLL + L F P I Q ++ V+H FSN GVR++ F+H G D
Sbjct: 200 CMYRLLVQLLDANQTVLDKFSAVPDPIPQWNNNACLHVTHVFSNIKMGVRFVSFEHRGQD 259
Query: 232 THYWAGWYGPRVTNSSITI 250
T +WAG YG RVTNSS+ +
Sbjct: 260 TQFWAGHYGARVTNSSVIV 278
>gi|22325388 F-box protein FBG4 isoform 1 [Homo sapiens]
Length = 287
Score = 163 bits (412), Expect = 2e-40
Identities = 89/263 (33%), Positives = 137/263 (52%), Gaps = 25/263 (9%)
Query: 6 INELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLW------------------ 47
++ LP +L+++ +HVP R L+ CR VC WRD++D T+W
Sbjct: 27 LDALPPELLVQVLSHVPPRSLVTRCRPVCRAWRDIVDGPTVWLLQLARDRSAEGRALYAV 86
Query: 48 KRKCLREGFITEDWDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVE 107
++CL E++ P+ + RNL+ N C E+GF W ++ +GG+ W +E
Sbjct: 87 AQRCLPSNEDKEEF--PLCALARYCLRAPFGRNLIFNSCGEQGFRGWEVE-HGGNGWAIE 143
Query: 108 DLSRDQRKEFPNDQVKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAAR 167
P + FVTS+ C K Q+VDL EG W+EL+D+ + +I V DW+ AR
Sbjct: 144 K----NLTPVPGAPSQTCFVTSFEWCSKRQLVDLVMEGVWQELLDSAQIEICVADWWGAR 199
Query: 168 PDCGSKYQLCVQLLSSAHAPLGTFQPDPATIQQKSDAKWREVSHTFSNYPPGVRYIWFQH 227
+CG YQL V+LL + F P + Q ++ R+VSH F+N+ G+RY+ F+
Sbjct: 200 ENCGCVYQLRVRLLDVYEKEVVKFSASPDPVLQWTERGCRQVSHVFTNFGKGIRYVSFEQ 259
Query: 228 GGVDTHYWAGWYGPRVTNSSITI 250
G D W G YG VT+SS+ +
Sbjct: 260 YGRDVSSWVGHYGALVTHSSVRV 282
>gi|18643385 F-box protein FBG4 isoform 2 [Homo sapiens]
Length = 278
Score = 163 bits (412), Expect = 2e-40
Identities = 89/263 (33%), Positives = 137/263 (52%), Gaps = 25/263 (9%)
Query: 6 INELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLW------------------ 47
++ LP +L+++ +HVP R L+ CR VC WRD++D T+W
Sbjct: 18 LDALPPELLVQVLSHVPPRSLVTRCRPVCRAWRDIVDGPTVWLLQLARDRSAEGRALYAV 77
Query: 48 KRKCLREGFITEDWDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVE 107
++CL E++ P+ + RNL+ N C E+GF W ++ +GG+ W +E
Sbjct: 78 AQRCLPSNEDKEEF--PLCALARYCLRAPFGRNLIFNSCGEQGFRGWEVE-HGGNGWAIE 134
Query: 108 DLSRDQRKEFPNDQVKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAAR 167
P + FVTS+ C K Q+VDL EG W+EL+D+ + +I V DW+ AR
Sbjct: 135 K----NLTPVPGAPSQTCFVTSFEWCSKRQLVDLVMEGVWQELLDSAQIEICVADWWGAR 190
Query: 168 PDCGSKYQLCVQLLSSAHAPLGTFQPDPATIQQKSDAKWREVSHTFSNYPPGVRYIWFQH 227
+CG YQL V+LL + F P + Q ++ R+VSH F+N+ G+RY+ F+
Sbjct: 191 ENCGCVYQLRVRLLDVYEKEVVKFSASPDPVLQWTERGCRQVSHVFTNFGKGIRYVSFEQ 250
Query: 228 GGVDTHYWAGWYGPRVTNSSITI 250
G D W G YG VT+SS+ +
Sbjct: 251 YGRDVSSWVGHYGALVTHSSVRV 273
>gi|47825361 non-specific cytotoxic cell receptor protein 1 homolog
[Homo sapiens]
Length = 275
Score = 85.1 bits (209), Expect = 5e-17
Identities = 58/184 (31%), Positives = 88/184 (47%), Gaps = 5/184 (2%)
Query: 68 WKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPNDQVKKYFV 127
WK+ R L+RNLL +P E + G + +E L + +++++
Sbjct: 92 WKLLLLRRPLYRNLLRSPNPEGINIYEPAPPTGPTQRPLETLGNFRGWYIRTEKLQQ--- 148
Query: 128 TSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQLLSS-AHA 186
+ +K Q VDL AEG WEEL+D +P I V DWF Y+L V LL++
Sbjct: 149 -NQSWTVKQQCVDLLAEGLWEELLDDEQPAITVMDWFEDSRLDACVYELHVWLLAADRRT 207
Query: 187 PLGTFQPDPATIQQKSDAKWREVSHTFSNYPPGVRYIWFQHGGVDTHYWAGWYGPRVTNS 246
+ P T + +W +VSH F +Y PGVR+I F H + G RVT+S
Sbjct: 208 VIAQHHVAPRTSGRGPPGRWVQVSHVFRHYGPGVRFIHFLHKAKNRMEPGGLRRTRVTDS 267
Query: 247 SITI 250
S+++
Sbjct: 268 SVSV 271
>gi|30795117 F-box only protein, helicase, 18 isoform 1 [Homo
sapiens]
Length = 1094
Score = 39.3 bits (90), Expect = 0.003
Identities = 19/50 (38%), Positives = 27/50 (54%), Gaps = 2/50 (4%)
Query: 2 AVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLID--LVTLWKR 49
A+ +I LP +L +F +P L N LVC LWR++I L WK+
Sbjct: 259 ALSHICSLPSEVLRHVFAFLPVEDLYWNLSLVCHLWREIISDPLFIPWKK 308
>gi|30795119 F-box only protein, helicase, 18 isoform 2 [Homo
sapiens]
Length = 1043
Score = 39.3 bits (90), Expect = 0.003
Identities = 19/50 (38%), Positives = 27/50 (54%), Gaps = 2/50 (4%)
Query: 2 AVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLID--LVTLWKR 49
A+ +I LP +L +F +P L N LVC LWR++I L WK+
Sbjct: 208 ALSHICSLPSEVLRHVFAFLPVEDLYWNLSLVCHLWREIISDPLFIPWKK 257
>gi|8923179 F-box and leucine-rich repeat protein 12 [Homo
sapiens]
Length = 326
Score = 38.5 bits (88), Expect = 0.006
Identities = 17/41 (41%), Positives = 28/41 (68%), Gaps = 1/41 (2%)
Query: 8 ELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWK 48
ELP+++LLE+F+++P R + R VC W+ L+D LW+
Sbjct: 6 ELPDSVLLEIFSYLPVRDRIRISR-VCHRWKRLVDDRWLWR 45
>gi|83035136 F-box protein 31 [Homo sapiens]
Length = 539
Score = 36.6 bits (83), Expect = 0.022
Identities = 17/53 (32%), Positives = 31/53 (58%), Gaps = 1/53 (1%)
Query: 8 ELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 60
ELP +L+E+F +P L + VC+ +R ++ T+W+R+C E + E+
Sbjct: 69 ELPPELLVEIFASLPGTDLP-SLAQVCTKFRRILHTDTIWRRRCREEYGVCEN 120
>gi|27312027 F-box only protein 16 [Homo sapiens]
Length = 292
Score = 36.2 bits (82), Expect = 0.029
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 5/75 (6%)
Query: 8 ELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITEDWDQPVAD 67
+LP + L +F+ + R L C VC W++L +L LW KCLR + P
Sbjct: 91 KLPRVLSLYIFSFLDPRSLC-RCAQVCWHWKNLAELDQLWMLKCLRFNWYINFSPTPFEQ 149
Query: 68 --WKIFY--FLRSLH 78
WK Y ++ LH
Sbjct: 150 GIWKKHYIQMVKELH 164
>gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [Homo
sapiens]
Length = 532
Score = 34.3 bits (77), Expect = 0.11
Identities = 15/65 (23%), Positives = 32/65 (49%), Gaps = 1/65 (1%)
Query: 8 ELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITEDWDQPVAD 67
+LP + + +F ++ ++L C V W+ + + LW R C +EG + + +
Sbjct: 52 QLPYELAINIFQYLDRKELG-RCAQVSKTWKVIAEDEVLWYRLCQQEGHLPDSSISDYSC 110
Query: 68 WKIFY 72
WK+ +
Sbjct: 111 WKLIF 115
>gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [Homo
sapiens]
Length = 598
Score = 34.3 bits (77), Expect = 0.11
Identities = 15/65 (23%), Positives = 32/65 (49%), Gaps = 1/65 (1%)
Query: 8 ELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITEDWDQPVAD 67
+LP + + +F ++ ++L C V W+ + + LW R C +EG + + +
Sbjct: 118 QLPYELAINIFQYLDRKELG-RCAQVSKTWKVIAEDEVLWYRLCQQEGHLPDSSISDYSC 176
Query: 68 WKIFY 72
WK+ +
Sbjct: 177 WKLIF 181
>gi|118402584 F-box and WD repeat domain containing 2 [Homo sapiens]
Length = 454
Score = 33.9 bits (76), Expect = 0.14
Identities = 24/73 (32%), Positives = 30/73 (41%), Gaps = 4/73 (5%)
Query: 25 QLLLNCRLVCSLWRDLIDLVT-LWKRKCLREGFITEDWDQPVADWKIFYFLRSLHRNLLH 83
Q LL C LV W +I T +W+ C G+ +D Q WK Y L L
Sbjct: 75 QTLLTCCLVSKQWNKVISACTEVWQTACKNLGWQIDDSVQDALHWKKVYLKAILRMKQLE 134
Query: 84 NPCAEEGFEFWSL 96
+ E FE SL
Sbjct: 135 D---HEAFETSSL 144
>gi|124248558 F-box and WD-40 domain protein 9 [Homo sapiens]
Length = 458
Score = 32.0 bits (71), Expect = 0.54
Identities = 16/45 (35%), Positives = 25/45 (55%)
Query: 9 LPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLR 53
LP +LLE+ +++ AR +L VC RDL+ W+ + LR
Sbjct: 82 LPPELLLEICSYLDARLVLHVLSRVCHALRDLVSDHVTWRLRALR 126
>gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [Homo
sapiens]
Length = 589
Score = 31.2 bits (69), Expect = 0.92
Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Query: 6 INELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREG 55
I+ LP+ + L + + + + LL + C WR L + LW+ KC EG
Sbjct: 163 ISLLPKELALYVLSFLEPKDLLQAAQ-TCRYWRILAEDNLLWREKCKEEG 211
>gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [Homo
sapiens]
Length = 707
Score = 31.2 bits (69), Expect = 0.92
Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Query: 6 INELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREG 55
I+ LP+ + L + + + + LL + C WR L + LW+ KC EG
Sbjct: 281 ISLLPKELALYVLSFLEPKDLLQAAQ-TCRYWRILAEDNLLWREKCKEEG 329
>gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [Homo
sapiens]
Length = 627
Score = 31.2 bits (69), Expect = 0.92
Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Query: 6 INELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREG 55
I+ LP+ + L + + + + LL + C WR L + LW+ KC EG
Sbjct: 201 ISLLPKELALYVLSFLEPKDLLQAAQ-TCRYWRILAEDNLLWREKCKEEG 249
>gi|236463969 neuregulin 1 isoform HRG-beta3b [Homo sapiens]
Length = 207
Score = 30.8 bits (68), Expect = 1.2
Identities = 19/53 (35%), Positives = 28/53 (52%), Gaps = 9/53 (16%)
Query: 86 CAEEGFEFWSLDVNGGDEWKVEDLSRDQR------KEFPNDQVKKYFVTSYYT 132
CAE+ F VNGG+ + V+DLS R EF D+ + Y + S+Y+
Sbjct: 148 CAEKEKTFC---VNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYS 197
>gi|236462773 neuregulin 1 isoform HRG-beta1d [Homo sapiens]
Length = 590
Score = 30.8 bits (68), Expect = 1.2
Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 10/75 (13%)
Query: 86 CAEEGFEFWSLDVNGGDEWKVEDLSRDQR------KEFPNDQVKKYFVTSYYTCLKSQVV 139
CAE+ F VNGG+ + V+DLS R EF D+ + Y + S+Y L + +
Sbjct: 127 CAEKEKTFC---VNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFM 183
Query: 140 DLKAEGYWEELMDTT 154
+ + E Y + ++ T
Sbjct: 184 EAE-ELYQKRVLTIT 197
>gi|236462348 neuregulin 1 isoform HRG-beta1b [Homo sapiens]
Length = 624
Score = 30.8 bits (68), Expect = 1.2
Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 10/75 (13%)
Query: 86 CAEEGFEFWSLDVNGGDEWKVEDLSRDQR------KEFPNDQVKKYFVTSYYTCLKSQVV 139
CAE+ F VNGG+ + V+DLS R EF D+ + Y + S+Y L + +
Sbjct: 161 CAEKEKTFC---VNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFM 217
Query: 140 DLKAEGYWEELMDTT 154
+ + E Y + ++ T
Sbjct: 218 EAE-ELYQKRVLTIT 231
>gi|236461509 neuregulin 1 isoform HRG-beta1c [Homo sapiens]
Length = 607
Score = 30.8 bits (68), Expect = 1.2
Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 10/75 (13%)
Query: 86 CAEEGFEFWSLDVNGGDEWKVEDLSRDQR------KEFPNDQVKKYFVTSYYTCLKSQVV 139
CAE+ F VNGG+ + V+DLS R EF D+ + Y + S+Y L + +
Sbjct: 144 CAEKEKTFC---VNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFM 200
Query: 140 DLKAEGYWEELMDTT 154
+ + E Y + ++ T
Sbjct: 201 EAE-ELYQKRVLTIT 214
>gi|116006959 neuregulin 1 isoform HRG-beta3 [Homo sapiens]
Length = 241
Score = 30.8 bits (68), Expect = 1.2
Identities = 19/53 (35%), Positives = 28/53 (52%), Gaps = 9/53 (16%)
Query: 86 CAEEGFEFWSLDVNGGDEWKVEDLSRDQR------KEFPNDQVKKYFVTSYYT 132
CAE+ F VNGG+ + V+DLS R EF D+ + Y + S+Y+
Sbjct: 182 CAEKEKTFC---VNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYS 231
>gi|116006955 neuregulin 1 isoform HRG-beta1 [Homo sapiens]
Length = 645
Score = 30.8 bits (68), Expect = 1.2
Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 10/75 (13%)
Query: 86 CAEEGFEFWSLDVNGGDEWKVEDLSRDQR------KEFPNDQVKKYFVTSYYTCLKSQVV 139
CAE+ F VNGG+ + V+DLS R EF D+ + Y + S+Y L + +
Sbjct: 182 CAEKEKTFC---VNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFM 238
Query: 140 DLKAEGYWEELMDTT 154
+ + E Y + ++ T
Sbjct: 239 EAE-ELYQKRVLTIT 252
>gi|7669518 neuregulin 1 isoform SMDF [Homo sapiens]
Length = 296
Score = 30.8 bits (68), Expect = 1.2
Identities = 19/53 (35%), Positives = 28/53 (52%), Gaps = 9/53 (16%)
Query: 86 CAEEGFEFWSLDVNGGDEWKVEDLSRDQR------KEFPNDQVKKYFVTSYYT 132
CAE+ F VNGG+ + V+DLS R EF D+ + Y + S+Y+
Sbjct: 237 CAEKEKTFC---VNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYS 286
>gi|116006967 neuregulin 1 isoform GGF2 [Homo sapiens]
Length = 422
Score = 30.8 bits (68), Expect = 1.2
Identities = 19/53 (35%), Positives = 28/53 (52%), Gaps = 9/53 (16%)
Query: 86 CAEEGFEFWSLDVNGGDEWKVEDLSRDQR------KEFPNDQVKKYFVTSYYT 132
CAE+ F VNGG+ + V+DLS R EF D+ + Y + S+Y+
Sbjct: 363 CAEKEKTFC---VNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYS 412
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.139 0.470
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,568,004
Number of Sequences: 37866
Number of extensions: 531968
Number of successful extensions: 1023
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 986
Number of HSP's gapped (non-prelim): 44
length of query: 255
length of database: 18,247,518
effective HSP length: 100
effective length of query: 155
effective length of database: 14,460,918
effective search space: 2241442290
effective search space used: 2241442290
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.