BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|62243652 SEC15-like 1 isoform b [Homo sapiens] (799 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|62243652 SEC15-like 1 isoform b [Homo sapiens] 1595 0.0 gi|65507403 SEC15-like 1 isoform a [Homo sapiens] 1551 0.0 gi|149363656 SEC15-like 2 [Homo sapiens] 1129 0.0 gi|118498356 kinectin 1 isoform a [Homo sapiens] 49 2e-05 gi|118498368 kinectin 1 isoform c [Homo sapiens] 49 2e-05 gi|33620775 kinectin 1 isoform a [Homo sapiens] 49 2e-05 gi|169207319 PREDICTED: hypothetical protein [Homo sapiens] 47 5e-05 gi|169207756 PREDICTED: hypothetical protein [Homo sapiens] 47 5e-05 gi|169207046 PREDICTED: hypothetical protein [Homo sapiens] 47 5e-05 gi|118498362 kinectin 1 isoform b [Homo sapiens] 44 6e-04 gi|50658082 centrosomal protein 70 kDa [Homo sapiens] 39 0.019 gi|4758398 folate hydrolase 1 isoform 1 [Homo sapiens] 37 0.055 gi|62548858 folate hydrolase 1 isoform 2 [Homo sapiens] 37 0.055 gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 37 0.072 gi|70980531 GGA binding partner [Homo sapiens] 37 0.072 gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 37 0.072 gi|75677376 coiled-coil domain containing 62 isoform b [Homo sap... 37 0.094 gi|30348972 coiled-coil domain containing 62 isoform a [Homo sap... 37 0.094 gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 37 0.094 gi|24308545 folate hydrolase 1B [Homo sapiens] 36 0.12 gi|33147080 STAM binding protein-like 1 [Homo sapiens] 36 0.12 gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo... 36 0.16 gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo... 36 0.16 gi|156104908 myosin heavy chain 6 [Homo sapiens] 36 0.16 gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 36 0.16 gi|27262630 nuclear autoantigenic sperm protein isoform 3 [Homo ... 35 0.21 gi|46852174 kinesin family member 3A [Homo sapiens] 35 0.27 gi|40807469 TRAF interacting protein [Homo sapiens] 35 0.27 gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 35 0.36 gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 35 0.36 >gi|62243652 SEC15-like 1 isoform b [Homo sapiens] Length = 799 Score = 1595 bits (4129), Expect = 0.0 Identities = 799/799 (100%), Positives = 799/799 (100%) Query: 1 MLEEETDQTYENVLAEIQSFELPVEATLRSVYDDQPNAHKKFMEKLDACIRNHDKEIEKM 60 MLEEETDQTYENVLAEIQSFELPVEATLRSVYDDQPNAHKKFMEKLDACIRNHDKEIEKM Sbjct: 1 MLEEETDQTYENVLAEIQSFELPVEATLRSVYDDQPNAHKKFMEKLDACIRNHDKEIEKM 60 Query: 61 CNFHHQGFVDAITELLKVRTDAEKLKVQVTDTNRRFQDAGKEVIVHTEDIIRCRIQQRNI 120 CNFHHQGFVDAITELLKVRTDAEKLKVQVTDTNRRFQDAGKEVIVHTEDIIRCRIQQRNI Sbjct: 61 CNFHHQGFVDAITELLKVRTDAEKLKVQVTDTNRRFQDAGKEVIVHTEDIIRCRIQQRNI 120 Query: 121 TTVVEKLQLCLPVLEMYSKLKEQMSAKRYYSALKTMEQLENVYFPWVSQYRFCQLMIENL 180 TTVVEKLQLCLPVLEMYSKLKEQMSAKRYYSALKTMEQLENVYFPWVSQYRFCQLMIENL Sbjct: 121 TTVVEKLQLCLPVLEMYSKLKEQMSAKRYYSALKTMEQLENVYFPWVSQYRFCQLMIENL 180 Query: 181 PKLREDIKEISMSDLKDFLESIRKHSDKIGETAMKQAQHQKTFSVSLQKQNKMKFGKNMY 240 PKLREDIKEISMSDLKDFLESIRKHSDKIGETAMKQAQHQKTFSVSLQKQNKMKFGKNMY Sbjct: 181 PKLREDIKEISMSDLKDFLESIRKHSDKIGETAMKQAQHQKTFSVSLQKQNKMKFGKNMY 240 Query: 241 INRDRIPEERNETVLKHSLEEEDENEEEILTVQDLVDFSPVYRCLHIYSVLGDEETFENY 300 INRDRIPEERNETVLKHSLEEEDENEEEILTVQDLVDFSPVYRCLHIYSVLGDEETFENY Sbjct: 241 INRDRIPEERNETVLKHSLEEEDENEEEILTVQDLVDFSPVYRCLHIYSVLGDEETFENY 300 Query: 301 YRKQRKKQARLVLQPQSNMHETVDGYRRYFTQIVGFFVVEDHILHVTQGLVTRAYTDELW 360 YRKQRKKQARLVLQPQSNMHETVDGYRRYFTQIVGFFVVEDHILHVTQGLVTRAYTDELW Sbjct: 301 YRKQRKKQARLVLQPQSNMHETVDGYRRYFTQIVGFFVVEDHILHVTQGLVTRAYTDELW 360 Query: 361 NMALSKIIAVLRAHSSYCTDPDLVLELKNLTVIFADTLQGYGFPVNRLFDLLFEIRDQYN 420 NMALSKIIAVLRAHSSYCTDPDLVLELKNLTVIFADTLQGYGFPVNRLFDLLFEIRDQYN Sbjct: 361 NMALSKIIAVLRAHSSYCTDPDLVLELKNLTVIFADTLQGYGFPVNRLFDLLFEIRDQYN 420 Query: 421 ETLLKKWAGVFRDIFEEDNYSPIPVVNEEEYKIVISKFPFQDPDLEKQSFPKKFPMSQSV 480 ETLLKKWAGVFRDIFEEDNYSPIPVVNEEEYKIVISKFPFQDPDLEKQSFPKKFPMSQSV Sbjct: 421 ETLLKKWAGVFRDIFEEDNYSPIPVVNEEEYKIVISKFPFQDPDLEKQSFPKKFPMSQSV 480 Query: 481 PHIYIQVKEFIYASLKFSESLHRSSTEIDDMLRKSTNLLLTRTLSSCLLNLIRKPHIGLT 540 PHIYIQVKEFIYASLKFSESLHRSSTEIDDMLRKSTNLLLTRTLSSCLLNLIRKPHIGLT Sbjct: 481 PHIYIQVKEFIYASLKFSESLHRSSTEIDDMLRKSTNLLLTRTLSSCLLNLIRKPHIGLT 540 Query: 541 ELVQIIINTTHLEQACKYLEDFITNITNISQETVHTTRLYGLSTFKDARHAAEGEIYTKL 600 ELVQIIINTTHLEQACKYLEDFITNITNISQETVHTTRLYGLSTFKDARHAAEGEIYTKL Sbjct: 541 ELVQIIINTTHLEQACKYLEDFITNITNISQETVHTTRLYGLSTFKDARHAAEGEIYTKL 600 Query: 601 NQKIDEFVQLADYDWTMSEPDGRASGYLMDLINFLRSIFQVFTHLPGKVAQTACMSACQH 660 NQKIDEFVQLADYDWTMSEPDGRASGYLMDLINFLRSIFQVFTHLPGKVAQTACMSACQH Sbjct: 601 NQKIDEFVQLADYDWTMSEPDGRASGYLMDLINFLRSIFQVFTHLPGKVAQTACMSACQH 660 Query: 661 LSTSLMQMLLDSELKQISMGAVQQFNLDVIQCELFASSEPVPGFQGDTLQLAFIDLRQLL 720 LSTSLMQMLLDSELKQISMGAVQQFNLDVIQCELFASSEPVPGFQGDTLQLAFIDLRQLL Sbjct: 661 LSTSLMQMLLDSELKQISMGAVQQFNLDVIQCELFASSEPVPGFQGDTLQLAFIDLRQLL 720 Query: 721 DLFMVWDWSTYLADYGQPASKYLRVNPNTALTLLEKMKDTSKKNNIFAQFRKNDRDKQKL 780 DLFMVWDWSTYLADYGQPASKYLRVNPNTALTLLEKMKDTSKKNNIFAQFRKNDRDKQKL Sbjct: 721 DLFMVWDWSTYLADYGQPASKYLRVNPNTALTLLEKMKDTSKKNNIFAQFRKNDRDKQKL 780 Query: 781 IETVVKQLRSLVNGMSQHM 799 IETVVKQLRSLVNGMSQHM Sbjct: 781 IETVVKQLRSLVNGMSQHM 799 >gi|65507403 SEC15-like 1 isoform a [Homo sapiens] Length = 804 Score = 1551 bits (4016), Expect = 0.0 Identities = 779/791 (98%), Positives = 783/791 (98%), Gaps = 1/791 (0%) Query: 10 YENVLAEIQSFELP-VEATLRSVYDDQPNAHKKFMEKLDACIRNHDKEIEKMCNFHHQGF 68 +E +L EI+S + V TLRSVYDDQPNAHKKFMEKLDACIRNHDKEIEKMCNFHHQGF Sbjct: 14 HERILQEIESTDTACVGPTLRSVYDDQPNAHKKFMEKLDACIRNHDKEIEKMCNFHHQGF 73 Query: 69 VDAITELLKVRTDAEKLKVQVTDTNRRFQDAGKEVIVHTEDIIRCRIQQRNITTVVEKLQ 128 VDAITELLKVRTDAEKLKVQVTDTNRRFQDAGKEVIVHTEDIIRCRIQQRNITTVVEKLQ Sbjct: 74 VDAITELLKVRTDAEKLKVQVTDTNRRFQDAGKEVIVHTEDIIRCRIQQRNITTVVEKLQ 133 Query: 129 LCLPVLEMYSKLKEQMSAKRYYSALKTMEQLENVYFPWVSQYRFCQLMIENLPKLREDIK 188 LCLPVLEMYSKLKEQMSAKRYYSALKTMEQLENVYFPWVSQYRFCQLMIENLPKLREDIK Sbjct: 134 LCLPVLEMYSKLKEQMSAKRYYSALKTMEQLENVYFPWVSQYRFCQLMIENLPKLREDIK 193 Query: 189 EISMSDLKDFLESIRKHSDKIGETAMKQAQHQKTFSVSLQKQNKMKFGKNMYINRDRIPE 248 EISMSDLKDFLESIRKHSDKIGETAMKQAQHQKTFSVSLQKQNKMKFGKNMYINRDRIPE Sbjct: 194 EISMSDLKDFLESIRKHSDKIGETAMKQAQHQKTFSVSLQKQNKMKFGKNMYINRDRIPE 253 Query: 249 ERNETVLKHSLEEEDENEEEILTVQDLVDFSPVYRCLHIYSVLGDEETFENYYRKQRKKQ 308 ERNETVLKHSLEEEDENEEEILTVQDLVDFSPVYRCLHIYSVLGDEETFENYYRKQRKKQ Sbjct: 254 ERNETVLKHSLEEEDENEEEILTVQDLVDFSPVYRCLHIYSVLGDEETFENYYRKQRKKQ 313 Query: 309 ARLVLQPQSNMHETVDGYRRYFTQIVGFFVVEDHILHVTQGLVTRAYTDELWNMALSKII 368 ARLVLQPQSNMHETVDGYRRYFTQIVGFFVVEDHILHVTQGLVTRAYTDELWNMALSKII Sbjct: 314 ARLVLQPQSNMHETVDGYRRYFTQIVGFFVVEDHILHVTQGLVTRAYTDELWNMALSKII 373 Query: 369 AVLRAHSSYCTDPDLVLELKNLTVIFADTLQGYGFPVNRLFDLLFEIRDQYNETLLKKWA 428 AVLRAHSSYCTDPDLVLELKNLTVIFADTLQGYGFPVNRLFDLLFEIRDQYNETLLKKWA Sbjct: 374 AVLRAHSSYCTDPDLVLELKNLTVIFADTLQGYGFPVNRLFDLLFEIRDQYNETLLKKWA 433 Query: 429 GVFRDIFEEDNYSPIPVVNEEEYKIVISKFPFQDPDLEKQSFPKKFPMSQSVPHIYIQVK 488 GVFRDIFEEDNYSPIPVVNEEEYKIVISKFPFQDPDLEKQSFPKKFPMSQSVPHIYIQVK Sbjct: 434 GVFRDIFEEDNYSPIPVVNEEEYKIVISKFPFQDPDLEKQSFPKKFPMSQSVPHIYIQVK 493 Query: 489 EFIYASLKFSESLHRSSTEIDDMLRKSTNLLLTRTLSSCLLNLIRKPHIGLTELVQIIIN 548 EFIYASLKFSESLHRSSTEIDDMLRKSTNLLLTRTLSSCLLNLIRKPHIGLTELVQIIIN Sbjct: 494 EFIYASLKFSESLHRSSTEIDDMLRKSTNLLLTRTLSSCLLNLIRKPHIGLTELVQIIIN 553 Query: 549 TTHLEQACKYLEDFITNITNISQETVHTTRLYGLSTFKDARHAAEGEIYTKLNQKIDEFV 608 TTHLEQACKYLEDFITNITNISQETVHTTRLYGLSTFKDARHAAEGEIYTKLNQKIDEFV Sbjct: 554 TTHLEQACKYLEDFITNITNISQETVHTTRLYGLSTFKDARHAAEGEIYTKLNQKIDEFV 613 Query: 609 QLADYDWTMSEPDGRASGYLMDLINFLRSIFQVFTHLPGKVAQTACMSACQHLSTSLMQM 668 QLADYDWTMSEPDGRASGYLMDLINFLRSIFQVFTHLPGKVAQTACMSACQHLSTSLMQM Sbjct: 614 QLADYDWTMSEPDGRASGYLMDLINFLRSIFQVFTHLPGKVAQTACMSACQHLSTSLMQM 673 Query: 669 LLDSELKQISMGAVQQFNLDVIQCELFASSEPVPGFQGDTLQLAFIDLRQLLDLFMVWDW 728 LLDSELKQISMGAVQQFNLDVIQCELFASSEPVPGFQGDTLQLAFIDLRQLLDLFMVWDW Sbjct: 674 LLDSELKQISMGAVQQFNLDVIQCELFASSEPVPGFQGDTLQLAFIDLRQLLDLFMVWDW 733 Query: 729 STYLADYGQPASKYLRVNPNTALTLLEKMKDTSKKNNIFAQFRKNDRDKQKLIETVVKQL 788 STYLADYGQPASKYLRVNPNTALTLLEKMKDTSKKNNIFAQFRKNDRDKQKLIETVVKQL Sbjct: 734 STYLADYGQPASKYLRVNPNTALTLLEKMKDTSKKNNIFAQFRKNDRDKQKLIETVVKQL 793 Query: 789 RSLVNGMSQHM 799 RSLVNGMSQHM Sbjct: 794 RSLVNGMSQHM 804 >gi|149363656 SEC15-like 2 [Homo sapiens] Length = 811 Score = 1129 bits (2920), Expect = 0.0 Identities = 564/797 (70%), Positives = 668/797 (83%), Gaps = 10/797 (1%) Query: 5 ETDQTYENVLAEIQSFELP-VEATLRSVYDDQPNAHKKFMEKLDACIRNHDKEIEKMCNF 63 ET +E +L EI+S + + TLRSVYD + H +FMEKL+ IRNHD+EIEKMCNF Sbjct: 13 ETAAEHERILREIESTDTACIGPTLRSVYDGEE--HGRFMEKLETRIRNHDREIEKMCNF 70 Query: 64 HHQGFVDAITELLKVRTDAEKLKVQVTDTNRRFQDAGKEVIVHTEDIIRCRIQQRNITTV 123 H+QGFVD+ITELLKVR +A+KLK QVTDTNR+ Q GKE+++ E++ +CR+QQRNI+ Sbjct: 71 HYQGFVDSITELLKVRGEAQKLKNQVTDTNRKLQHEGKELVIAMEELKQCRLQQRNISAT 130 Query: 124 VEKLQLCLPVLEMYSKLKEQMSAKRYYSALKTMEQLENVYFPWVSQYRFCQLMIENLPKL 183 V+KL LCLPVLEMYSKL++QM KR+Y ALKT+E LE+ Y P VS YRFC++M++N+PKL Sbjct: 131 VDKLMLCLPVLEMYSKLRDQMKTKRHYPALKTLEHLEHTYLPQVSHYRFCKVMVDNIPKL 190 Query: 184 REDIKEISMSDLKDFLESIRKHSDKIGETAMKQAQHQKTFSVSLQKQ----NKMKFGKNM 239 RE+IK++SMSDLKDFLESIRKHSDKIGETAMKQAQ Q+ + +Q +K K K+ Sbjct: 191 REEIKDVSMSDLKDFLESIRKHSDKIGETAMKQAQQQRNLDNIVLQQPRIGSKRKSKKDA 250 Query: 240 YINRDRIPEERNETVLKHS--LEEEDE-NEEEILTVQDLVDFSPVYRCLHIYSVLGDEET 296 YI D E + + S L+ EDE ++EE+ QDLVDFSPVYRCLHIYSVLG ET Sbjct: 251 YIIFDTEIESTSPKSEQDSGILDVEDEEDDEEVPGAQDLVDFSPVYRCLHIYSVLGARET 310 Query: 297 FENYYRKQRKKQARLVLQPQSNMHETVDGYRRYFTQIVGFFVVEDHILHVTQGLVTRAYT 356 FENYYRKQR+KQARLVLQP SNMHET+DGYR+YF QIVGFFVVEDHILH TQGLV RAY Sbjct: 311 FENYYRKQRRKQARLVLQPPSNMHETLDGYRKYFNQIVGFFVVEDHILHTTQGLVNRAYI 370 Query: 357 DELWNMALSKIIAVLRAHSSYCTDPDLVLELKNLTVIFADTLQGYGFPVNRLFDLLFEIR 416 DELW MALSK IA LR HSSYC+DP+LVL+LKNL V+FADTLQ YGFPVN+LFD+L EIR Sbjct: 371 DELWEMALSKTIAALRTHSSYCSDPNLVLDLKNLIVLFADTLQVYGFPVNQLFDMLLEIR 430 Query: 417 DQYNETLLKKWAGVFRDIFEEDNYSPIPVVNEEEYKIVISKFPFQDPDLEKQSFPKKFPM 476 DQY+ETLLKKWAG+FR+I + DNYSPIPV +EE YK V+ +FPFQD +LEKQ FPKKFP Sbjct: 431 DQYSETLLKKWAGIFRNILDSDNYSPIPVTSEEMYKKVVGQFPFQDIELEKQPFPKKFPF 490 Query: 477 SQSVPHIYIQVKEFIYASLKFSESLHRSSTEIDDMLRKSTNLLLTRTLSSCLLNLIRKPH 536 S+ VP +Y Q+KEFIYA LKFSE LH SSTE+DDM+RKSTNLLLTRTLS+ L N+I++ + Sbjct: 491 SEFVPKVYNQIKEFIYACLKFSEDLHLSSTEVDDMIRKSTNLLLTRTLSNSLQNVIKRKN 550 Query: 537 IGLTELVQIIINTTHLEQACKYLEDFITNITNISQETVHTTRLYGLSTFKDARHAAEGEI 596 IGLTELVQIIINTTHLE++CKYLE+FITNITN+ ETVHTT+LYG +TFKDARHAAE EI Sbjct: 551 IGLTELVQIIINTTHLEKSCKYLEEFITNITNVLPETVHTTKLYGTTTFKDARHAAEEEI 610 Query: 597 YTKLNQKIDEFVQLADYDWTMSEPDGRASGYLMDLINFLRSIFQVFTHLPGKVAQTACMS 656 YT LNQKID+F+QLADYDW + +AS YL+DLI FLRS F VFTHLPGKVAQTACMS Sbjct: 611 YTNLNQKIDQFLQLADYDWMTGDLGNKASDYLVDLIAFLRSTFAVFTHLPGKVAQTACMS 670 Query: 657 ACQHLSTSLMQMLLDSELKQISMGAVQQFNLDVIQCELFASSEPVPGFQGDTLQLAFIDL 716 AC+HL+TSLMQ+LL++E++Q+++GA+QQFNLDV +CE FA S PVPGFQ DTLQLAFIDL Sbjct: 671 ACKHLATSLMQLLLEAEVRQLTLGALQQFNLDVRECEQFARSGPVPGFQEDTLQLAFIDL 730 Query: 717 RQLLDLFMVWDWSTYLADYGQPASKYLRVNPNTALTLLEKMKDTSKKNNIFAQFRKNDRD 776 RQLLDLF+ WDWSTYLADYGQP KYLRVNP TALTLLEKMKDTS+KNN+FAQFRKN+RD Sbjct: 731 RQLLDLFIQWDWSTYLADYGQPNCKYLRVNPVTALTLLEKMKDTSRKNNMFAQFRKNERD 790 Query: 777 KQKLIETVVKQLRSLVN 793 KQKLI+TV KQLR L++ Sbjct: 791 KQKLIDTVAKQLRGLIS 807 >gi|118498356 kinectin 1 isoform a [Homo sapiens] Length = 1357 Score = 48.9 bits (115), Expect = 2e-05 Identities = 67/296 (22%), Positives = 131/296 (44%), Gaps = 40/296 (13%) Query: 1 MLEEETDQTYENVLAEI-----QSFELPVEAT-LRSVYDDQPNAHKKFMEKLDACIRNHD 54 +LEE+ N + E Q+ L E L+++ +QPN K +E+++ CI+ D Sbjct: 684 LLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPN--KDVVEQMEKCIQEKD 741 Query: 55 KEIEKMCNFHHQGFVDAIT---ELLKVRTDAEKLKVQVTDTNRRFQDAGKEVIVHTEDII 111 ++++ + G + T EL +RT+ L +V D + D + E Sbjct: 742 EKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKK 801 Query: 112 RCRIQQRNITTVVEKLQLCLPVLEMYSKLKEQMSAKRYYSALKTMEQLENVYFPWVSQYR 171 + I +V E L+ L L++ +K K K+ ALK E++ NV Q Sbjct: 802 VIHEKDGKIKSVEELLEAEL--LKVANKEKTVQDLKQEIKALK--EEIGNVQLEKAQQLS 857 Query: 172 FCQLM--IENLPK------------LREDIKEIS-----MSDLKDFLESIRKHSDKIGET 212 + ++NL K L E K+++ + DL++ ES++ H ++ + Sbjct: 858 ITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQH 917 Query: 213 AMKQAQHQKTFS----VSLQKQNKMKFGKNMYINRDRIPEERNETVLKHSLEEEDE 264 +K+A F V +K+N++K + M ++R + ++T L +++E++ Sbjct: 918 NLKEASSASQFEELEIVLKEKENELKRLEAML--KERESDLSSKTQLLQDVQDENK 971 >gi|118498368 kinectin 1 isoform c [Homo sapiens] Length = 1300 Score = 48.9 bits (115), Expect = 2e-05 Identities = 67/296 (22%), Positives = 131/296 (44%), Gaps = 40/296 (13%) Query: 1 MLEEETDQTYENVLAEI-----QSFELPVEAT-LRSVYDDQPNAHKKFMEKLDACIRNHD 54 +LEE+ N + E Q+ L E L+++ +QPN K +E+++ CI+ D Sbjct: 684 LLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPN--KDVVEQMEKCIQEKD 741 Query: 55 KEIEKMCNFHHQGFVDAIT---ELLKVRTDAEKLKVQVTDTNRRFQDAGKEVIVHTEDII 111 ++++ + G + T EL +RT+ L +V D + D + E Sbjct: 742 EKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKK 801 Query: 112 RCRIQQRNITTVVEKLQLCLPVLEMYSKLKEQMSAKRYYSALKTMEQLENVYFPWVSQYR 171 + I +V E L+ L L++ +K K K+ ALK E++ NV Q Sbjct: 802 VIHEKDGKIKSVEELLEAEL--LKVANKEKTVQDLKQEIKALK--EEIGNVQLEKAQQLS 857 Query: 172 FCQLM--IENLPK------------LREDIKEIS-----MSDLKDFLESIRKHSDKIGET 212 + ++NL K L E K+++ + DL++ ES++ H ++ + Sbjct: 858 ITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQH 917 Query: 213 AMKQAQHQKTFS----VSLQKQNKMKFGKNMYINRDRIPEERNETVLKHSLEEEDE 264 +K+A F V +K+N++K + M ++R + ++T L +++E++ Sbjct: 918 NLKEASSASQFEELEIVLKEKENELKRLEAML--KERESDLSSKTQLLQDVQDENK 971 >gi|33620775 kinectin 1 isoform a [Homo sapiens] Length = 1357 Score = 48.9 bits (115), Expect = 2e-05 Identities = 67/296 (22%), Positives = 131/296 (44%), Gaps = 40/296 (13%) Query: 1 MLEEETDQTYENVLAEI-----QSFELPVEAT-LRSVYDDQPNAHKKFMEKLDACIRNHD 54 +LEE+ N + E Q+ L E L+++ +QPN K +E+++ CI+ D Sbjct: 684 LLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPN--KDVVEQMEKCIQEKD 741 Query: 55 KEIEKMCNFHHQGFVDAIT---ELLKVRTDAEKLKVQVTDTNRRFQDAGKEVIVHTEDII 111 ++++ + G + T EL +RT+ L +V D + D + E Sbjct: 742 EKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKK 801 Query: 112 RCRIQQRNITTVVEKLQLCLPVLEMYSKLKEQMSAKRYYSALKTMEQLENVYFPWVSQYR 171 + I +V E L+ L L++ +K K K+ ALK E++ NV Q Sbjct: 802 VIHEKDGKIKSVEELLEAEL--LKVANKEKTVQDLKQEIKALK--EEIGNVQLEKAQQLS 857 Query: 172 FCQLM--IENLPK------------LREDIKEIS-----MSDLKDFLESIRKHSDKIGET 212 + ++NL K L E K+++ + DL++ ES++ H ++ + Sbjct: 858 ITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQH 917 Query: 213 AMKQAQHQKTFS----VSLQKQNKMKFGKNMYINRDRIPEERNETVLKHSLEEEDE 264 +K+A F V +K+N++K + M ++R + ++T L +++E++ Sbjct: 918 NLKEASSASQFEELEIVLKEKENELKRLEAML--KERESDLSSKTQLLQDVQDENK 971 >gi|169207319 PREDICTED: hypothetical protein [Homo sapiens] Length = 828 Score = 47.4 bits (111), Expect = 5e-05 Identities = 101/488 (20%), Positives = 191/488 (39%), Gaps = 63/488 (12%) Query: 109 DIIRC----RIQQRNITTVVEKLQ----LCLPVLEMYSKLKEQMSAKRYYSALKTM-EQL 159 D +C +I ++I V+KL+ + +LE+ E M + Y L+T+ + Sbjct: 59 DYFKCNEEAKIFLKDIAVAVKKLEEMRKATIDLLEI-----ESMELNKLYYLLETLPNSI 113 Query: 160 ENVYFPWVSQYRFCQLMIENLPKLREDIKEISMSDLKDFLESIRKHSDKIGETAMKQAQH 219 + V R L N K+R E + LK + + K+++ +GE + A+ Sbjct: 114 KRELEECVRDARRLNLFEINTIKMRITRTENEIELLKKKITDLTKYNEALGEKQEELARK 173 Query: 220 QKTFSVSLQKQNKMKFGKNMYINR--DRIPEERNETVLKHSLEEEDENEEEILTVQDLVD 277 F +SL + + K +YIN +I +R + L+ +E E E + L+ Sbjct: 174 HARFVLSLNQTMEKKATTTVYINETYTKINLKREDIALQKKCIQEAEELMEKERAEYLIR 233 Query: 278 FSPVYRCLHIYSVLGDEETFENYYRKQRKKQARLVLQPQSNMHETVDGYRRYFTQIVGFF 337 + ++ + + + E Y Q+KK+ + S + ETV V Sbjct: 234 KQELTAQINEFENTREVKRMETY---QKKKELDKLQTKMSKIKETV---------TVSAA 281 Query: 338 VVEDHILHVTQGLVTRAYTDELWNMALSKIIAVLRAHSSYCTDPDLVLELKNLTVIFADT 397 V+ DH L + + + Y ++ + L K +A+L A + TD + L I D Sbjct: 282 VLSDHNLEIARLHESIRYWEQEVS-ELKKDLAILEAKLCFFTD-----NKEKLDDISNDE 335 Query: 398 LQGYGFPVNRLFDLLFEIRDQYNETLLKKWAGVFRDIFEEDNYSPIPVVNEEEYKIVISK 457 + + +L + L R +Y + L +K + R +V EE K + K Sbjct: 336 KNEFLNKIKQLVETLHAARMEYKD-LREKMKTLARQ---------YKIVLSEEEKAFLQK 385 Query: 458 FPFQDPDLEKQSF--PKKFPMSQSVPHIYIQVKEFIYASLKFSESLHRSSTEIDDML--- 512 D + ++ +F K++ +SQ + +K + E + T + Sbjct: 386 QKIHDENQKQLTFISQKEYFLSQK----RVDIKNMEEGLITLQELQQATKTVYQQQIKIL 441 Query: 513 -----RKSTNLLLTRTLSSCLLNLIRKPHIGLTELVQIIINT-THLEQACKYLEDFITNI 566 R+S ++T+ +CL RK H T ++ I T Q + + N Sbjct: 442 SANLERESQRCVITQWKMACL----RKKHARWTAKIKAEIQAITEKIQNAEVRRIELLNE 497 Query: 567 TNISQETV 574 T+ Q+ + Sbjct: 498 TSFRQQEI 505 >gi|169207756 PREDICTED: hypothetical protein [Homo sapiens] Length = 828 Score = 47.4 bits (111), Expect = 5e-05 Identities = 101/488 (20%), Positives = 191/488 (39%), Gaps = 63/488 (12%) Query: 109 DIIRC----RIQQRNITTVVEKLQ----LCLPVLEMYSKLKEQMSAKRYYSALKTM-EQL 159 D +C +I ++I V+KL+ + +LE+ E M + Y L+T+ + Sbjct: 59 DYFKCNEEAKIFLKDIAVAVKKLEEMRKATIDLLEI-----ESMELNKLYYLLETLPNSI 113 Query: 160 ENVYFPWVSQYRFCQLMIENLPKLREDIKEISMSDLKDFLESIRKHSDKIGETAMKQAQH 219 + V R L N K+R E + LK + + K+++ +GE + A+ Sbjct: 114 KRELEECVRDARRLNLFEINTIKMRITRTENEIELLKKKITDLTKYNEALGEKQEELARK 173 Query: 220 QKTFSVSLQKQNKMKFGKNMYINR--DRIPEERNETVLKHSLEEEDENEEEILTVQDLVD 277 F +SL + + K +YIN +I +R + L+ +E E E + L+ Sbjct: 174 HARFVLSLNQTMEKKATTTVYINETYTKINLKREDIALQKKCIQEAEELMEKERAEYLIR 233 Query: 278 FSPVYRCLHIYSVLGDEETFENYYRKQRKKQARLVLQPQSNMHETVDGYRRYFTQIVGFF 337 + ++ + + + E Y Q+KK+ + S + ETV V Sbjct: 234 KQELTAQINEFENTREVKRMETY---QKKKELDKLQTKMSKIKETV---------TVSAA 281 Query: 338 VVEDHILHVTQGLVTRAYTDELWNMALSKIIAVLRAHSSYCTDPDLVLELKNLTVIFADT 397 V+ DH L + + + Y ++ + L K +A+L A + TD + L I D Sbjct: 282 VLSDHNLEIARLHESIRYWEQEVS-ELKKDLAILEAKLCFFTD-----NKEKLDDISNDE 335 Query: 398 LQGYGFPVNRLFDLLFEIRDQYNETLLKKWAGVFRDIFEEDNYSPIPVVNEEEYKIVISK 457 + + +L + L R +Y + L +K + R +V EE K + K Sbjct: 336 KNEFLNKIKQLVETLHAARMEYKD-LREKMKTLARQ---------YKIVLSEEEKAFLQK 385 Query: 458 FPFQDPDLEKQSF--PKKFPMSQSVPHIYIQVKEFIYASLKFSESLHRSSTEIDDML--- 512 D + ++ +F K++ +SQ + +K + E + T + Sbjct: 386 QKIHDENQKQLTFISQKEYFLSQK----RVDIKNMEEGLITLQELQQATKTVYQQQIKIL 441 Query: 513 -----RKSTNLLLTRTLSSCLLNLIRKPHIGLTELVQIIINT-THLEQACKYLEDFITNI 566 R+S ++T+ +CL RK H T ++ I T Q + + N Sbjct: 442 SANLERESQRCVITQWKMACL----RKKHARWTAKIKAEIQAITEKIQNAEVRRIELLNE 497 Query: 567 TNISQETV 574 T+ Q+ + Sbjct: 498 TSFRQQEI 505 >gi|169207046 PREDICTED: hypothetical protein [Homo sapiens] Length = 828 Score = 47.4 bits (111), Expect = 5e-05 Identities = 101/488 (20%), Positives = 191/488 (39%), Gaps = 63/488 (12%) Query: 109 DIIRC----RIQQRNITTVVEKLQ----LCLPVLEMYSKLKEQMSAKRYYSALKTM-EQL 159 D +C +I ++I V+KL+ + +LE+ E M + Y L+T+ + Sbjct: 59 DYFKCNEEAKIFLKDIAVAVKKLEEMRKATIDLLEI-----ESMELNKLYYLLETLPNSI 113 Query: 160 ENVYFPWVSQYRFCQLMIENLPKLREDIKEISMSDLKDFLESIRKHSDKIGETAMKQAQH 219 + V R L N K+R E + LK + + K+++ +GE + A+ Sbjct: 114 KRELEECVRDARRLNLFEINTIKMRITRTENEIELLKKKITDLTKYNEALGEKQEELARK 173 Query: 220 QKTFSVSLQKQNKMKFGKNMYINR--DRIPEERNETVLKHSLEEEDENEEEILTVQDLVD 277 F +SL + + K +YIN +I +R + L+ +E E E + L+ Sbjct: 174 HARFVLSLNQTMEKKATTTVYINETYTKINLKREDIALQKKCIQEAEELMEKERAEYLIR 233 Query: 278 FSPVYRCLHIYSVLGDEETFENYYRKQRKKQARLVLQPQSNMHETVDGYRRYFTQIVGFF 337 + ++ + + + E Y Q+KK+ + S + ETV V Sbjct: 234 KQELTAQINEFENTREVKRMETY---QKKKELDKLQTKMSKIKETV---------TVSAA 281 Query: 338 VVEDHILHVTQGLVTRAYTDELWNMALSKIIAVLRAHSSYCTDPDLVLELKNLTVIFADT 397 V+ DH L + + + Y ++ + L K +A+L A + TD + L I D Sbjct: 282 VLSDHNLEIARLHESIRYWEQEVS-ELKKDLAILEAKLCFFTD-----NKEKLDDISNDE 335 Query: 398 LQGYGFPVNRLFDLLFEIRDQYNETLLKKWAGVFRDIFEEDNYSPIPVVNEEEYKIVISK 457 + + +L + L R +Y + L +K + R +V EE K + K Sbjct: 336 KNEFLNKIKQLVETLHAARMEYKD-LREKMKTLARQ---------YKIVLSEEEKAFLQK 385 Query: 458 FPFQDPDLEKQSF--PKKFPMSQSVPHIYIQVKEFIYASLKFSESLHRSSTEIDDML--- 512 D + ++ +F K++ +SQ + +K + E + T + Sbjct: 386 QKIHDENQKQLTFISQKEYFLSQK----RVDIKNMEEGLITLQELQQATKTVYQQQIKIL 441 Query: 513 -----RKSTNLLLTRTLSSCLLNLIRKPHIGLTELVQIIINT-THLEQACKYLEDFITNI 566 R+S ++T+ +CL RK H T ++ I T Q + + N Sbjct: 442 SANLERESQRCVITQWKMACL----RKKHARWTAKIKAEIQAITEKIQNAEVRRIELLNE 497 Query: 567 TNISQETV 574 T+ Q+ + Sbjct: 498 TSFRQQEI 505 >gi|118498362 kinectin 1 isoform b [Homo sapiens] Length = 1306 Score = 43.9 bits (102), Expect = 6e-04 Identities = 60/279 (21%), Positives = 124/279 (44%), Gaps = 29/279 (10%) Query: 1 MLEEETDQTYENVLAEI-----QSFELPVEAT-LRSVYDDQPNAHKKFMEKLDACIRNHD 54 +LEE+ N + E Q+ L E L+++ +QPN K +E+++ CI+ D Sbjct: 684 LLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPN--KDVVEQMEKCIQEKD 741 Query: 55 KEIEKMCNFHHQGFVDAIT---ELLKVRTDAEKLKVQVTDTNRRFQDAGKEVIVHTEDII 111 ++++ + G + T EL +RT+ L +V D + D + E Sbjct: 742 EKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKK 801 Query: 112 RCRIQQRNITTVVEKLQLCLPVLEMYSKLKEQMSAKRYYSALKTMEQLENVYFPWVSQYR 171 + I +V E L+ L L++ +K K S +++L+N+ Q Sbjct: 802 VIHEKDGKIKSVEELLEAEL--LKVANKEKTVQ-----LSITSKVQELQNLLKGKEEQMN 854 Query: 172 FCQLMIENLPKLREDIKEIS--MSDLKDFLESIRKHSDKIGETAMKQAQHQKTFS----V 225 + ++E K D+ + DL++ ES++ H ++ + +K+A F V Sbjct: 855 TMKAVLEEKEK---DLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIV 911 Query: 226 SLQKQNKMKFGKNMYINRDRIPEERNETVLKHSLEEEDE 264 +K+N++K + M ++R + ++T L +++E++ Sbjct: 912 LKEKENELKRLEAML--KERESDLSSKTQLLQDVQDENK 948 >gi|50658082 centrosomal protein 70 kDa [Homo sapiens] Length = 597 Score = 38.9 bits (89), Expect = 0.019 Identities = 36/171 (21%), Positives = 71/171 (41%), Gaps = 15/171 (8%) Query: 169 QYRFCQLMIENLPKLREDIK---------EISMSDLKDFLESIRKHSDKIGETAMKQAQH 219 Q Q +IE +LR +++ E +DL+ +ES++ ++ + ++ +A H Sbjct: 80 QQNMIQELIETNQQLRNELQLEQSRAANQEQRANDLEQIMESVKSKIGELEDESLSRACH 139 Query: 220 QKTFSVSLQKQNKMKFGKNMYINRDRIPEERNETVLKHSLEEEDENEEEILTVQDLVDFS 279 Q+ LQK+ K K + + R +E L+ + + EE+ + Q+ V Sbjct: 140 QQNKIKDLQKEQKTLQVKCQHYKKKRTEQEETIASLQMEVCRLKKEEEDRIVTQNRVF-- 197 Query: 280 PVYRCLHIYSVLGDEE---TFENYYRKQRKKQARLVLQPQSNMHETVDGYR 327 Y C + + D + + Y K RK + + + E + YR Sbjct: 198 -AYLCKRVPHTVLDRQLLCLIDYYESKIRKIHTQRQYKEDESQSEEENDYR 247 >gi|4758398 folate hydrolase 1 isoform 1 [Homo sapiens] Length = 750 Score = 37.4 bits (85), Expect = 0.055 Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 1/78 (1%) Query: 149 YYSALKTMEQLENVYFPWVSQYRFCQLMIENLPKLREDIKEISMSDLKDFLESIRKHSDK 208 Y+S +T E +E Y P + +Y + + D +D+ +RK++DK Sbjct: 552 YHSVYETYELVEKFYDP-MFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADK 610 Query: 209 IGETAMKQAQHQKTFSVS 226 I +MK Q KT+SVS Sbjct: 611 IYSISMKHPQEMKTYSVS 628 >gi|62548858 folate hydrolase 1 isoform 2 [Homo sapiens] Length = 719 Score = 37.4 bits (85), Expect = 0.055 Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 1/78 (1%) Query: 149 YYSALKTMEQLENVYFPWVSQYRFCQLMIENLPKLREDIKEISMSDLKDFLESIRKHSDK 208 Y+S +T E +E Y P + +Y + + D +D+ +RK++DK Sbjct: 552 YHSVYETYELVEKFYDP-MFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADK 610 Query: 209 IGETAMKQAQHQKTFSVS 226 I +MK Q KT+SVS Sbjct: 611 IYSISMKHPQEMKTYSVS 628 >gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] Length = 1088 Score = 37.0 bits (84), Expect = 0.072 Identities = 52/227 (22%), Positives = 97/227 (42%), Gaps = 18/227 (7%) Query: 51 RNHDKEIEKMCNFHHQGFVDAITELLKVRTDAEKLKVQVTDTNRRFQDAGKEVIVHTEDI 110 R+H K ++ Q TELL ++T E L Q +D+ + + KE + E Sbjct: 430 RSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHI-EVLKESLTAKEQ- 487 Query: 111 IRCRIQQRNITTVVEKLQLCLPVLEMYSKLKEQMSAKRYYSALKTMEQLENVYFPWVSQY 170 R I Q + + +L+ +L +K + M+ ++ A + L+++ + Sbjct: 488 -RAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQA-GEIHDLKDMLDVKERKV 545 Query: 171 RFCQLMIENLPKLREDIKEISMSDLKDFLESIRKHSDKIGE--TAMKQAQHQKTFSVSLQ 228 Q IENL + D KE MS LK+ ++S++ + T +++A +K ++ Sbjct: 546 NVLQKKIENLQEQLRD-KEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERL 604 Query: 229 KQNKMKFGKNMYINRDRIPEERNETVLKHSLEEEDENEEEILTVQDL 275 K+ RDR E+ E + + + +D E+ L DL Sbjct: 605 KE-----------QRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDL 640 >gi|70980531 GGA binding partner [Homo sapiens] Length = 441 Score = 37.0 bits (84), Expect = 0.072 Identities = 39/148 (26%), Positives = 71/148 (47%), Gaps = 11/148 (7%) Query: 2 LEEETDQTYENVLAEIQ-SFELPVEATLRSVYDDQPNAHKKFMEKLDACIRNHDKEIEKM 60 LEEE + E +++ + E +A L+ V +++ N K E+ + H K+ EK+ Sbjct: 292 LEEERQRNKEALVSAAKLEKEAVKDAVLKVVEEERKNLEKAHAEERELWKTEHAKDQEKV 351 Query: 61 CNFHHQGFVDAITELLKVRTDAEKLKVQVTDTNRRFQDAGKEVIVHTED-IIRCRIQQRN 119 Q AI E K+ E +K + + +R + A +E + T D +I +Q+ Sbjct: 352 ----SQEIQKAIQEQRKI--SQETVKAAIIEEQKRSEKAVEEAVKRTRDELIEYIKEQKR 405 Query: 120 ITTVVEKLQLCLPVLEMY-SKLKEQMSA 146 + V+ Q L LE++ S ++Q+SA Sbjct: 406 LDQVIR--QRSLSSLELFLSCAQKQLSA 431 >gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] Length = 1780 Score = 37.0 bits (84), Expect = 0.072 Identities = 52/234 (22%), Positives = 102/234 (43%), Gaps = 37/234 (15%) Query: 74 ELLKVRTDAEKLKVQVTDTNRRFQDAGKEVIVHTEDIIRCRIQQRNITTVVEKLQLCLPV 133 +L + D LK ++TD ++ + KEV V ++ RI+ I + +K C Sbjct: 1237 DLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIK---INELEKKKNQCSQE 1293 Query: 134 LEM----YSKLKEQMSAKRYYSALKTMEQ------------------LENVYFPWVSQYR 171 L+M +LKEQ++ ++ A++ E+ LE V Q + Sbjct: 1294 LDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQ 1353 Query: 172 FCQLMIENLPKLREDI----KEISMSDLKDFLESIRKH---SDKIGETAMKQAQHQKTFS 224 + +E + +L ++ ++ + + K+ S ++H +D +G+ Q + Q++ Sbjct: 1354 VLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQ 1413 Query: 225 VSLQKQNKMKFGKNMYINRDRIPEE-RNETVLKHSLEEE----DENEEEILTVQ 273 + K K M I + + E RN+ + K++ + E +NE EILT Q Sbjct: 1414 KYNADRKKWLEEKMMLITQAKEAENIRNKEMKKYAEDRERFFKQQNEMEILTAQ 1467 >gi|75677376 coiled-coil domain containing 62 isoform b [Homo sapiens] Length = 684 Score = 36.6 bits (83), Expect = 0.094 Identities = 62/302 (20%), Positives = 121/302 (40%), Gaps = 46/302 (15%) Query: 40 KKFMEKLDACIRNHDKEIEKMCNFHHQGFVDAITELLKVRTDAEKLKVQVTDTNRRFQDA 99 +K ++ L +++ DKE+ M H Q + + KV T E+ + ++R Sbjct: 27 RKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLEGELHKR---- 82 Query: 100 GKEVIVH-TEDIIRCRIQQRNITTVVEKLQLCLPVLEM---YSKLKEQMSAKRYYSALKT 155 E+I T+ + Q T ++K QL L + +S L + R + T Sbjct: 83 -TEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLEARNETLSNT 141 Query: 156 MEQLENVYFPWVSQYRFCQLMIENLPKLREDIKEISMSDLKDFLESIRKHSD-----KIG 210 + +L V Q + + + + KL++ KD +E++ +D K+ Sbjct: 142 LVELS----AQVGQLQAREQALTTMIKLKD----------KDIIEAVNHIADCSGKFKML 187 Query: 211 ETAMKQAQHQKTFSVSLQKQNKMKFGKNMYINRDRIPEERNETVLKHSLEEEDENEEEIL 270 E A++ A+ +T V ++ K K K + I +++ E+ NE E +E EEI+ Sbjct: 188 EHALRDAKMAETCIVKEKQDYKQKL-KALKIEVNKLKEDLNE-----KTTENNEQREEII 241 Query: 271 TVQDLVDFSPVYRCLHIYSVLGDEETFENYYRKQRKKQARLVLQPQSNMHETVDGYRRYF 330 ++ CLH DE F K++ + + Q + + R+ + Sbjct: 242 RLKQ------EKSCLH------DELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIY 289 Query: 331 TQ 332 + Sbjct: 290 VK 291 >gi|30348972 coiled-coil domain containing 62 isoform a [Homo sapiens] Length = 682 Score = 36.6 bits (83), Expect = 0.094 Identities = 62/302 (20%), Positives = 121/302 (40%), Gaps = 46/302 (15%) Query: 40 KKFMEKLDACIRNHDKEIEKMCNFHHQGFVDAITELLKVRTDAEKLKVQVTDTNRRFQDA 99 +K ++ L +++ DKE+ M H Q + + KV T E+ + ++R Sbjct: 27 RKELQLLIGELKDRDKELNDMVAVHQQQLLSWEEDRQKVLTLEERCSKLEGELHKR---- 82 Query: 100 GKEVIVH-TEDIIRCRIQQRNITTVVEKLQLCLPVLEM---YSKLKEQMSAKRYYSALKT 155 E+I T+ + Q T ++K QL L + +S L + R + T Sbjct: 83 -TEIIRSLTKKVKALESNQMECQTALQKTQLQLQEMAQKATHSSLLSEDLEARNETLSNT 141 Query: 156 MEQLENVYFPWVSQYRFCQLMIENLPKLREDIKEISMSDLKDFLESIRKHSD-----KIG 210 + +L V Q + + + + KL++ KD +E++ +D K+ Sbjct: 142 LVELS----AQVGQLQAREQALTTMIKLKD----------KDIIEAVNHIADCSGKFKML 187 Query: 211 ETAMKQAQHQKTFSVSLQKQNKMKFGKNMYINRDRIPEERNETVLKHSLEEEDENEEEIL 270 E A++ A+ +T V ++ K K K + I +++ E+ NE E +E EEI+ Sbjct: 188 EHALRDAKMAETCIVKEKQDYKQKL-KALKIEVNKLKEDLNE-----KTTENNEQREEII 241 Query: 271 TVQDLVDFSPVYRCLHIYSVLGDEETFENYYRKQRKKQARLVLQPQSNMHETVDGYRRYF 330 ++ CLH DE F K++ + + Q + + R+ + Sbjct: 242 RLKQ------EKSCLH------DELLFTVEREKRKDELLNIAKSKQERTNSELHNLRQIY 289 Query: 331 TQ 332 + Sbjct: 290 VK 291 >gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 36.6 bits (83), Expect = 0.094 Identities = 66/334 (19%), Positives = 124/334 (37%), Gaps = 69/334 (20%) Query: 4 EETDQTYENVLAEIQSFELPVEATLRSVYDDQPNAHKKFMEKLDACIRNHDKEIEKM--- 60 EE + + E+ +I +L + V D+ A K E++D RNH + +E M Sbjct: 1551 EEAEASLEHEEGKILRIQLELNQVKSEV--DRKIAEKD--EEIDQLKRNHIRIVESMQST 1606 Query: 61 CNFHHQGFVDAITELLKVRTDAEKLKVQVTDTNRRFQDAG----------KEVIVHTEDI 110 + + DAI K+ D ++++Q+ NR +A K+ +H +D Sbjct: 1607 LDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDA 1666 Query: 111 IRCRIQQRNITTVVEK-LQLCLPVLEMYSKLKEQMSAKRYYSALKTMEQLENVYFPWVSQ 169 +R + + +VE+ L +E EQ R + + ++ E V Sbjct: 1667 LRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQN 1726 Query: 170 YRFCQLMIENLPKLREDIKEISMSDLKDFLESIRKHSDK----IGETAMKQAQHQKTFSV 225 +I KL DI ++ +++D L+ R +K I + AM + +K Sbjct: 1727 TS----LINTKKKLETDISQMQ-GEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDT 1781 Query: 226 SLQ----KQNKMKFGKNMYINRDRIPE--------------------------------- 248 S K+N + K++ + D + Sbjct: 1782 SAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAE 1841 Query: 249 -----ERNETVLKHSLEEEDENEEEILTVQDLVD 277 ++E +K + +E+ + IL +QDLVD Sbjct: 1842 AVKGLRKHERRVKELTYQTEEDRKNILRLQDLVD 1875 >gi|24308545 folate hydrolase 1B [Homo sapiens] Length = 442 Score = 36.2 bits (82), Expect = 0.12 Identities = 22/78 (28%), Positives = 37/78 (47%), Gaps = 1/78 (1%) Query: 149 YYSALKTMEQLENVYFPWVSQYRFCQLMIENLPKLREDIKEISMSDLKDFLESIRKHSDK 208 Y+S +T E +E Y P + +Y + + D +D+ +RK++DK Sbjct: 244 YHSVYETYELVEKFYDP-MFKYHLTVAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADK 302 Query: 209 IGETAMKQAQHQKTFSVS 226 I +MK Q KT+S+S Sbjct: 303 IYNISMKHPQEMKTYSLS 320 >gi|33147080 STAM binding protein-like 1 [Homo sapiens] Length = 436 Score = 36.2 bits (82), Expect = 0.12 Identities = 36/197 (18%), Positives = 83/197 (42%), Gaps = 41/197 (20%) Query: 140 LKEQMSAKRYYSALKTMEQLENVYFP-------WVSQYRFCQLMIENLPKLREDIKEISM 192 + E ++ +RY+ + ME++ +VY +V +F L +E LP R D ++ ++ Sbjct: 42 ISEDITPRRYFRSGVEMERMASVYLEEGNLENAFVLYNKFITLFVEKLPNHR-DYQQCAV 100 Query: 193 SDLKDFLESIRK----HSDKIGETAMKQAQHQKTFSVSLQKQNKMKFGKNMYINRDRIPE 248 + +D ++ +++ +D++ +K+ + + LQ +NK K + R+ E Sbjct: 101 PEKQDIMKKLKEIAFPRTDELKNDLLKK--YNVEYQEYLQSKNKYKAEILKKLEHQRLIE 158 Query: 249 ERNETVLKHSLEEEDENEEEILTVQDLVDFSPVYRCLHIYSVLGDEETFENYYRKQRKKQ 308 + + + + ++ E+ L FE+ +KQ + Sbjct: 159 AERKRIAQ--MRQQQLESEQFLF-------------------------FEDQLKKQELAR 191 Query: 309 ARLVLQPQSNMHETVDG 325 ++ Q S + E +DG Sbjct: 192 GQMRSQQTSGLSEQIDG 208 >gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo sapiens] Length = 1591 Score = 35.8 bits (81), Expect = 0.16 Identities = 47/228 (20%), Positives = 90/228 (39%), Gaps = 40/228 (17%) Query: 74 ELLKVRTDAEKLKVQVTDTNRRFQDAGKEVIV----------------HTEDIIRCRIQQ 117 E +RT+ KL ++ D N +Q E+ H E+ + + Sbjct: 1096 ETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEKDQCISELISRHEEESNILKAEL 1155 Query: 118 RNITTV------VEKLQLCLPVLEMYSKLKEQMSAKRYYSALKTMEQLENVYFPWVSQYR 171 +T++ +EK L ++E+ SKL ++SA K +Q E Sbjct: 1156 NKVTSLHNQAFEIEK-NLKEQIIELQSKLDSELSALERQKDEKITQQEEKY--------- 1205 Query: 172 FCQLMIENLPKLREDIKEISMSDLKDFLESIRKHSDKIGETAMKQAQHQKTFSVSLQKQN 231 + +I+NL K R+ + D + ++ + D+ +TA+K+ + ++ V + Sbjct: 1206 --EAIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEFKLEREV-VEKELLE 1262 Query: 232 KMKFGKNMYINRDRIPEERNET-----VLKHSLEEEDENEEEILTVQD 274 K+K +N I R ++ L+ L+EE E L Q+ Sbjct: 1263 KVKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQE 1310 >gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo sapiens] Length = 1594 Score = 35.8 bits (81), Expect = 0.16 Identities = 47/228 (20%), Positives = 90/228 (39%), Gaps = 40/228 (17%) Query: 74 ELLKVRTDAEKLKVQVTDTNRRFQDAGKEVIV----------------HTEDIIRCRIQQ 117 E +RT+ KL ++ D N +Q E+ H E+ + + Sbjct: 1096 ETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEKDQCISELISRHEEESNILKAEL 1155 Query: 118 RNITTV------VEKLQLCLPVLEMYSKLKEQMSAKRYYSALKTMEQLENVYFPWVSQYR 171 +T++ +EK L ++E+ SKL ++SA K +Q E Sbjct: 1156 NKVTSLHNQAFEIEK-NLKEQIIELQSKLDSELSALERQKDEKITQQEEKY--------- 1205 Query: 172 FCQLMIENLPKLREDIKEISMSDLKDFLESIRKHSDKIGETAMKQAQHQKTFSVSLQKQN 231 + +I+NL K R+ + D + ++ + D+ +TA+K+ + ++ V + Sbjct: 1206 --EAIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEFKLEREV-VEKELLE 1262 Query: 232 KMKFGKNMYINRDRIPEERNET-----VLKHSLEEEDENEEEILTVQD 274 K+K +N I R ++ L+ L+EE E L Q+ Sbjct: 1263 KVKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQE 1310 >gi|156104908 myosin heavy chain 6 [Homo sapiens] Length = 1939 Score = 35.8 bits (81), Expect = 0.16 Identities = 60/298 (20%), Positives = 122/298 (40%), Gaps = 73/298 (24%) Query: 44 EKLDACIRNHDKEIEKMCNFHHQGFVDAIT----ELLKVRT----DAEKLKVQVTDTNRR 95 E+++ RNH + ++ + Q +DA T E+L+V+ D ++++Q++ NR Sbjct: 1583 EEMEQAKRNHQRVVDSL-----QTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRM 1637 Query: 96 FQDAGKEVI----------VHTEDIIRCRIQ-QRNITTVVEKLQLCLPVLEMYSKLKEQM 144 +A K+V + +D +R + NI V + L LE + EQ Sbjct: 1638 AAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQT 1697 Query: 145 SAKRYYSA---LKTMEQLENVYFPWVSQYRFCQLMIENLPKLREDIKEI----------- 190 R + ++T E+++ ++ S + M +L +L+ +++E Sbjct: 1698 ERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKA 1757 Query: 191 --SMSDLKDFLESIRKHSD---------KIGETAMKQAQHQKTFSVSLQKQNKMKFGKNM 239 +++D E ++K D K E +K QH+ + +Q +K GK Sbjct: 1758 KKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHR----LDEAEQIALKGGKKQ 1813 Query: 240 YINRD-RIPE-------------------ERNETVLKHSLEEEDENEEEILTVQDLVD 277 + R+ E ++E +K + +E+++ +L +QDLVD Sbjct: 1814 LQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVD 1871 >gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo sapiens] Length = 1937 Score = 35.8 bits (81), Expect = 0.16 Identities = 63/333 (18%), Positives = 135/333 (40%), Gaps = 67/333 (20%) Query: 4 EETDQTYENVLAEIQSFELPVEATLRSVYDDQPNAHKKFMEKLDACIRNHDKEIEKM--- 60 EE + + E+ +I +L + V D+ A K E++D RNH + +E M Sbjct: 1548 EEAEASLEHEEGKILRIQLELNQVKSEV--DRKIAEKD--EEIDQLKRNHTRVVETMQST 1603 Query: 61 CNFHHQGFVDAITELLKVRTDAEKLKVQVTDTNR----------RFQDAGKEVIVHTEDI 110 + + DA+ K+ D ++++Q+ NR Q KE +H +D Sbjct: 1604 LDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDA 1663 Query: 111 IRCRIQQRNITTVVEKLQLCLP--VLEMYSKLKEQMSAKRY--YSALKTMEQLENVYFPW 166 +R + + +VE+ L + E+++ L++ +++ L E+++ ++ Sbjct: 1664 LRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQN 1723 Query: 167 VSQYRFCQLMIENLPKLREDIKEI-------------SMSDLKDFLESIRKHSD------ 207 S + + ++ +L+ +++E+ +++D E ++K D Sbjct: 1724 TSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 1783 Query: 208 ---KIGETAMKQAQHQKTFSVSLQKQNKMKFGKNMYINRD-RIPE--------------- 248 K E +K QH+ + +Q +K GK + R+ E Sbjct: 1784 RMKKNLEQTVKDLQHR----LDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEA 1839 Query: 249 ----ERNETVLKHSLEEEDENEEEILTVQDLVD 277 ++E +K + +E+ + +L +QDLVD Sbjct: 1840 VKGLRKHERRVKELTYQTEEDRKNVLRLQDLVD 1872 >gi|27262630 nuclear autoantigenic sperm protein isoform 3 [Homo sapiens] Length = 449 Score = 35.4 bits (80), Expect = 0.21 Identities = 46/230 (20%), Positives = 99/230 (43%), Gaps = 25/230 (10%) Query: 3 EEETDQTYENVLAEIQSFELPVEATLRSVYDDQPNAHKKFMEKLDACIRN---HDKEIEK 59 EEE ++T + L E ++ T S DD+ N + M D+ + N + E E+ Sbjct: 117 EEEGEKTEDESLVENND---NIDETEGSEEDDKENDKTEEMPN-DSVLENKSLQENEEEE 172 Query: 60 MCNFHHQGFVDAITELLKVRTDAEKLKVQVTDTNRRFQDAGKEVIVHTEDIIRCRIQQRN 119 + N + + +++ R + ++ ++ + + + ++ N Sbjct: 173 IGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVS--------------VESEN 218 Query: 120 ITTVVEKLQLCLPVLEMYSKLKEQMSAKRYYSALKTMEQLENVYFPWVSQYRFCQLMIEN 179 VE+ Q CL + E Y + +++ A+ +Y L + Y V+Q+ +IEN Sbjct: 219 YVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQ-LGLAYGYNSQYDEAVAQFSKSIEVIEN 277 Query: 180 -LPKLREDIKEI--SMSDLKDFLESIRKHSDKIGETAMKQAQHQKTFSVS 226 + L E +KE S ++ K +E +++ +I E + Q++ +V+ Sbjct: 278 RMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVA 327 >gi|46852174 kinesin family member 3A [Homo sapiens] Length = 699 Score = 35.0 bits (79), Expect = 0.27 Identities = 37/142 (26%), Positives = 60/142 (42%), Gaps = 11/142 (7%) Query: 126 KLQLCLPVLEMYSKLKEQMSAKRYYSALKTMEQLENVYF-PWVSQYRFCQLMIENLPKLR 184 K +C + E +S RY + K ++ + P + R Q IE L K Sbjct: 315 KTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKL 374 Query: 185 EDIKEISMSDLKDFLESIRKHSDKIGETAMKQAQHQKTFSVSLQKQNKMKFGKNMYINRD 244 E+ +EIS SD+ E + + +GE K+ + + VS K +M+ Sbjct: 375 EEGEEISGSDISGSEEDDDEEGE-VGEDGEKRKKRRGKKKVSPDKMIEMQA--------- 424 Query: 245 RIPEERNETVLKHSLEEEDENE 266 +I EER K +EEE+ N+ Sbjct: 425 KIDEERKALETKLDMEEEERNK 446 >gi|40807469 TRAF interacting protein [Homo sapiens] Length = 469 Score = 35.0 bits (79), Expect = 0.27 Identities = 45/158 (28%), Positives = 73/158 (46%), Gaps = 31/158 (19%) Query: 81 DAEKLKVQVTDTNRRFQDAGKE-----VIVHTEDIIRCRIQQRNITTVVEKLQLCLPVLE 135 DAE LK ++ + + KE VI+ D +R +++RN T V LQ L E Sbjct: 75 DAEFLKNELDNVRAQLSQKDKEKRDSQVII---DTLRDTLEERNATVV--SLQQALGKAE 129 Query: 136 MY-SKLKEQMS---------------AKRYYSALKTMEQLENVYFPWVSQYRFCQLMIEN 179 M S LK+QM A+R S +KTMEQ+E + SQ + MI + Sbjct: 130 MLCSTLKKQMKYLEQQQDETKQAQEEARRLRSKMKTMEQIELLL---QSQRPEVEEMIRD 186 Query: 180 LPKLREDIKEISM--SDLKDFLESIRKHSDKIGETAMK 215 + + ++++++ LK E++++ GE A K Sbjct: 187 MGVGQSAVEQLAVYCVSLKKEYENLKEARKASGEVADK 224 >gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sapiens] Length = 1843 Score = 34.7 bits (78), Expect = 0.36 Identities = 43/199 (21%), Positives = 90/199 (45%), Gaps = 26/199 (13%) Query: 79 RTDAEK-LKVQVTDTNRRFQDAGKEVIVHTEDIIRCRIQQRNITTVVEKLQLCLPVLEMY 137 RT++ + L V++ D + + +E+ TE ++ C+ + + +++LQ E Sbjct: 242 RTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQ-----ENM 296 Query: 138 SKLKEQMSAKRYYSALKTM-------EQLENVYFPWVSQYRFCQLMIENLPKLREDIKEI 190 + L + SA+ Y L + ++LE+ + + + + +L+ED + + Sbjct: 297 NLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVL 356 Query: 191 --SMSDLKDFLESIRKHSDKIGETAMKQAQHQKTFSVSLQKQNKMKFGKNMYINRDRIPE 248 + + L+D LE R SDK+ E + Q + K + M+ ++M +R +I E Sbjct: 357 LETKTMLEDQLEGTRARSDKLHELEKENLQLK-------AKLHDMEMERDM--DRKKIEE 407 Query: 249 --ERNETVLKHSLEEEDEN 265 E N T+ + DE+ Sbjct: 408 LMEENMTLEMAQKQSMDES 426 >gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo sapiens] Length = 1870 Score = 34.7 bits (78), Expect = 0.36 Identities = 43/199 (21%), Positives = 90/199 (45%), Gaps = 26/199 (13%) Query: 79 RTDAEK-LKVQVTDTNRRFQDAGKEVIVHTEDIIRCRIQQRNITTVVEKLQLCLPVLEMY 137 RT++ + L V++ D + + +E+ TE ++ C+ + + +++LQ E Sbjct: 242 RTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQ-----ENM 296 Query: 138 SKLKEQMSAKRYYSALKTM-------EQLENVYFPWVSQYRFCQLMIENLPKLREDIKEI 190 + L + SA+ Y L + ++LE+ + + + + +L+ED + + Sbjct: 297 NLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVL 356 Query: 191 --SMSDLKDFLESIRKHSDKIGETAMKQAQHQKTFSVSLQKQNKMKFGKNMYINRDRIPE 248 + + L+D LE R SDK+ E + Q + K + M+ ++M +R +I E Sbjct: 357 LETKTMLEDQLEGTRARSDKLHELEKENLQLK-------AKLHDMEMERDM--DRKKIEE 407 Query: 249 --ERNETVLKHSLEEEDEN 265 E N T+ + DE+ Sbjct: 408 LMEENMTLEMAQKQSMDES 426 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.135 0.386 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 27,433,219 Number of Sequences: 37866 Number of extensions: 1178741 Number of successful extensions: 4356 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 8 Number of HSP's successfully gapped in prelim test: 101 Number of HSP's that attempted gapping in prelim test: 4272 Number of HSP's gapped (non-prelim): 183 length of query: 799 length of database: 18,247,518 effective HSP length: 110 effective length of query: 689 effective length of database: 14,082,258 effective search space: 9702675762 effective search space used: 9702675762 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.