Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 61742817
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|61742817 krev interaction trapped 1 isoform 2 [Homo sapiens]
(688 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|61742817 krev interaction trapped 1 isoform 2 [Homo sapiens] 1391 0.0
gi|37221184 krev interaction trapped 1 isoform 1 [Homo sapiens] 1368 0.0
gi|37221182 krev interaction trapped 1 isoform 1 [Homo sapiens] 1368 0.0
gi|37221187 krev interaction trapped 1 isoform 1 [Homo sapiens] 1368 0.0
gi|31581522 krev interaction trapped 1 isoform 1 [Homo sapiens] 1368 0.0
gi|13994263 FERM domain containing 8 [Homo sapiens] 100 3e-21
gi|32967260 neurofibromin 2 isoform 5 [Homo sapiens] 54 5e-07
gi|32967254 neurofibromin 2 isoform 2 [Homo sapiens] 54 6e-07
gi|32967266 neurofibromin 2 isoform 2 [Homo sapiens] 54 6e-07
gi|32451486 neurofibromin 2 isoform 2 [Homo sapiens] 54 6e-07
gi|4557795 neurofibromin 2 isoform 1 [Homo sapiens] 54 6e-07
gi|4506467 radixin [Homo sapiens] 53 8e-07
gi|156938343 talin 2 [Homo sapiens] 53 8e-07
gi|4505257 moesin [Homo sapiens] 53 1e-06
gi|223029410 talin 1 [Homo sapiens] 52 1e-06
gi|32967514 neurofibromin 2 isoform 7 [Homo sapiens] 52 1e-06
gi|32967264 neurofibromin 2 isoform 7 [Homo sapiens] 52 1e-06
gi|32967262 neurofibromin 2 isoform 6 [Homo sapiens] 50 7e-06
gi|161702986 ezrin [Homo sapiens] 48 3e-05
gi|21614499 ezrin [Homo sapiens] 48 3e-05
gi|110815813 ankyrin repeat and FYVE domain containing 1 isoform... 47 5e-05
gi|116534990 ankyrin-like protein 1 [Homo sapiens] 47 8e-05
gi|24233530 ankyrin repeat domain 44 [Homo sapiens] 45 2e-04
gi|34304381 inversin isoform a [Homo sapiens] 45 3e-04
gi|34304379 inversin isoform b [Homo sapiens] 45 3e-04
gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 44 7e-04
gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 44 7e-04
gi|96975023 ankyrin repeat and death domain containing 1A [Homo ... 42 0.002
gi|23510377 KN motif and ankyrin repeat domains 1 isoform b [Hom... 42 0.002
gi|64464726 KN motif and ankyrin repeat domains 1 isoform a [Hom... 42 0.002
>gi|61742817 krev interaction trapped 1 isoform 2 [Homo sapiens]
Length = 688
Score = 1391 bits (3600), Expect = 0.0
Identities = 688/688 (100%), Positives = 688/688 (100%)
Query: 1 MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60
MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG
Sbjct: 1 MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60
Query: 61 NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120
NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN
Sbjct: 61 NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120
Query: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180
TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP
Sbjct: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180
Query: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240
SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY
Sbjct: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240
Query: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKYGKVEATRILLEKGKCNP 300
TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKYGKVEATRILLEKGKCNP
Sbjct: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKYGKVEATRILLEKGKCNP 300
Query: 301 NLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAA 360
NLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAA
Sbjct: 301 NLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAA 360
Query: 361 KLLKEAINKPYEKVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSE 420
KLLKEAINKPYEKVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSE
Sbjct: 361 KLLKEAINKPYEKVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSE 420
Query: 421 NLSLQLKPYHKPLQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAI 480
NLSLQLKPYHKPLQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAI
Sbjct: 421 NLSLQLKPYHKPLQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAI 480
Query: 481 LILFDEARYNLLKGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVT 540
LILFDEARYNLLKGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVT
Sbjct: 481 LILFDEARYNLLKGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVT 540
Query: 541 KLKSKAPHWTNRILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKA 600
KLKSKAPHWTNRILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKA
Sbjct: 541 KLKSKAPHWTNRILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKA 600
Query: 601 SPSNHKVIPVYVGVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSF 660
SPSNHKVIPVYVGVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSF
Sbjct: 601 SPSNHKVIPVYVGVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSF 660
Query: 661 IVHTKQAGLVVKLLMKLNGQLMPTERNS 688
IVHTKQAGLVVKLLMKLNGQLMPTERNS
Sbjct: 661 IVHTKQAGLVVKLLMKLNGQLMPTERNS 688
>gi|37221184 krev interaction trapped 1 isoform 1 [Homo sapiens]
Length = 736
Score = 1368 bits (3541), Expect = 0.0
Identities = 688/736 (93%), Positives = 688/736 (93%), Gaps = 48/736 (6%)
Query: 1 MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60
MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG
Sbjct: 1 MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60
Query: 61 NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120
NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN
Sbjct: 61 NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120
Query: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180
TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP
Sbjct: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180
Query: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240
SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY
Sbjct: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240
Query: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDK------------------ 282
TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDK
Sbjct: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD 300
Query: 283 ------------------------------YGKVEATRILLEKGKCNPNLLNGQLSSPLH 312
YGKVEATRILLEKGKCNPNLLNGQLSSPLH
Sbjct: 301 SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH 360
Query: 313 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 372
FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE
Sbjct: 361 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 420
Query: 373 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 432
KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP
Sbjct: 421 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 480
Query: 433 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 492
LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL
Sbjct: 481 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 540
Query: 493 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 552
KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR
Sbjct: 541 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 600
Query: 553 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 612
ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV
Sbjct: 601 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 660
Query: 613 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 672
GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK
Sbjct: 661 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 720
Query: 673 LLMKLNGQLMPTERNS 688
LLMKLNGQLMPTERNS
Sbjct: 721 LLMKLNGQLMPTERNS 736
>gi|37221182 krev interaction trapped 1 isoform 1 [Homo sapiens]
Length = 736
Score = 1368 bits (3541), Expect = 0.0
Identities = 688/736 (93%), Positives = 688/736 (93%), Gaps = 48/736 (6%)
Query: 1 MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60
MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG
Sbjct: 1 MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60
Query: 61 NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120
NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN
Sbjct: 61 NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120
Query: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180
TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP
Sbjct: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180
Query: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240
SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY
Sbjct: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240
Query: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDK------------------ 282
TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDK
Sbjct: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD 300
Query: 283 ------------------------------YGKVEATRILLEKGKCNPNLLNGQLSSPLH 312
YGKVEATRILLEKGKCNPNLLNGQLSSPLH
Sbjct: 301 SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH 360
Query: 313 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 372
FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE
Sbjct: 361 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 420
Query: 373 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 432
KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP
Sbjct: 421 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 480
Query: 433 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 492
LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL
Sbjct: 481 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 540
Query: 493 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 552
KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR
Sbjct: 541 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 600
Query: 553 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 612
ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV
Sbjct: 601 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 660
Query: 613 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 672
GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK
Sbjct: 661 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 720
Query: 673 LLMKLNGQLMPTERNS 688
LLMKLNGQLMPTERNS
Sbjct: 721 LLMKLNGQLMPTERNS 736
>gi|37221187 krev interaction trapped 1 isoform 1 [Homo sapiens]
Length = 736
Score = 1368 bits (3541), Expect = 0.0
Identities = 688/736 (93%), Positives = 688/736 (93%), Gaps = 48/736 (6%)
Query: 1 MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60
MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG
Sbjct: 1 MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60
Query: 61 NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120
NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN
Sbjct: 61 NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120
Query: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180
TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP
Sbjct: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180
Query: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240
SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY
Sbjct: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240
Query: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDK------------------ 282
TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDK
Sbjct: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD 300
Query: 283 ------------------------------YGKVEATRILLEKGKCNPNLLNGQLSSPLH 312
YGKVEATRILLEKGKCNPNLLNGQLSSPLH
Sbjct: 301 SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH 360
Query: 313 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 372
FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE
Sbjct: 361 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 420
Query: 373 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 432
KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP
Sbjct: 421 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 480
Query: 433 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 492
LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL
Sbjct: 481 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 540
Query: 493 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 552
KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR
Sbjct: 541 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 600
Query: 553 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 612
ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV
Sbjct: 601 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 660
Query: 613 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 672
GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK
Sbjct: 661 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 720
Query: 673 LLMKLNGQLMPTERNS 688
LLMKLNGQLMPTERNS
Sbjct: 721 LLMKLNGQLMPTERNS 736
>gi|31581522 krev interaction trapped 1 isoform 1 [Homo sapiens]
Length = 736
Score = 1368 bits (3541), Expect = 0.0
Identities = 688/736 (93%), Positives = 688/736 (93%), Gaps = 48/736 (6%)
Query: 1 MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60
MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG
Sbjct: 1 MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60
Query: 61 NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120
NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN
Sbjct: 61 NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120
Query: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180
TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP
Sbjct: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180
Query: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240
SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY
Sbjct: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240
Query: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDK------------------ 282
TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDK
Sbjct: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD 300
Query: 283 ------------------------------YGKVEATRILLEKGKCNPNLLNGQLSSPLH 312
YGKVEATRILLEKGKCNPNLLNGQLSSPLH
Sbjct: 301 SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH 360
Query: 313 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 372
FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE
Sbjct: 361 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 420
Query: 373 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 432
KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP
Sbjct: 421 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 480
Query: 433 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 492
LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL
Sbjct: 481 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 540
Query: 493 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 552
KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR
Sbjct: 541 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 600
Query: 553 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 612
ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV
Sbjct: 601 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 660
Query: 613 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 672
GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK
Sbjct: 661 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 720
Query: 673 LLMKLNGQLMPTERNS 688
LLMKLNGQLMPTERNS
Sbjct: 721 LLMKLNGQLMPTERNS 736
>gi|13994263 FERM domain containing 8 [Homo sapiens]
Length = 464
Score = 100 bits (250), Expect = 3e-21
Identities = 72/263 (27%), Positives = 123/263 (46%), Gaps = 22/263 (8%)
Query: 399 IMEGMRLSQETQQYFTIWICSENLSLQLKPYHKPLQHVRDWPEILAELTNL---DPQRET 455
+ E ++L F +W+ S L +QLKP H+P + R WPE+L T+ D +
Sbjct: 61 VREVLQLPDIALDVFALWLVSPLLEVQLKPKHQPYKLGRQWPELLLRFTSAPDDDVAMDE 120
Query: 456 PQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLLKGFYTAPDAKLITLASLLLQIVY 515
P L RR+V P E QI D + +L++EA+ N+L Y L +L+ ++
Sbjct: 121 PFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALGALVCRVQL 180
Query: 516 GNYESKKHKQGFLNEENLKSIVPVTKLK-------------SKAPHWTNRILHEYK---N 559
G Y+ + L E+ L S +P K ++A +L+ Y+
Sbjct: 181 GPYQPGRPAACDLREK-LDSFLPAHLCKRGQSLFAALRGRGARAGPGEQGLLNAYRQVQE 239
Query: 560 LSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHK--VIPVYVGVNIK 617
+S+ G + R +L C E+P YG AFF G++ A H+ PV V ++++
Sbjct: 240 VSSDGGCEAALGTHYRAYLLKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPVSVAISLE 299
Query: 618 GLHLLNMETKALLISLKYGCFMW 640
G+H+++ K +L+ L++ W
Sbjct: 300 GVHVIDSREKHVLLGLRFQELSW 322
>gi|32967260 neurofibromin 2 isoform 5 [Homo sapiens]
Length = 548
Score = 53.9 bits (128), Expect = 5e-07
Identities = 55/242 (22%), Positives = 102/242 (42%), Gaps = 23/242 (9%)
Query: 441 EILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL-KGFYTAP 499
E E+ + D +E P F P E+++ + + F + + +L + Y P
Sbjct: 34 EFNCEVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYCPP 93
Query: 500 DAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNRILHEYKN 559
+A ++ LAS +Q YG+Y+ HK+GFL +E L + + W RI Y
Sbjct: 94 EASVL-LASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWY-- 150
Query: 560 LSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYVGVNIKGL 619
+E + + +L+ ++ YG +F + N K + +GV+ GL
Sbjct: 151 ---AEHRGRARDEAEMEYLKIAQDLEMYGVNYF--------AIRNKKGTELLLGVDALGL 199
Query: 620 HLLNMETKALLISLKYGCFMW----QLGDTDTCFQIHSMENKMSFIVHTKQAGLVVKLLM 675
H+ + E + ++ K F W + +D F I ++ K+ V KL++
Sbjct: 200 HIYDPENR---LTPKIS-FPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLIL 255
Query: 676 KL 677
+L
Sbjct: 256 QL 257
>gi|32967254 neurofibromin 2 isoform 2 [Homo sapiens]
Length = 590
Score = 53.5 bits (127), Expect = 6e-07
Identities = 54/244 (22%), Positives = 104/244 (42%), Gaps = 23/244 (9%)
Query: 439 WPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL-KGFYT 497
W ++ ++ + D +E P F P E+++ + + F + + +L + Y
Sbjct: 74 WLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYC 133
Query: 498 APDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNRILHEY 557
P+A ++ LAS +Q YG+Y+ HK+GFL +E L + + W RI Y
Sbjct: 134 PPEASVL-LASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWY 192
Query: 558 KNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYVGVNIK 617
+E + + +L+ ++ YG +F + N K + +GV+
Sbjct: 193 -----AEHRGRARDEAEMEYLKIAQDLEMYGVNYF--------AIRNKKGTELLLGVDAL 239
Query: 618 GLHLLNMETKALLISLKYGCFMW----QLGDTDTCFQIHSMENKMSFIVHTKQAGLVVKL 673
GLH+ + E + ++ K F W + +D F I ++ K+ V KL
Sbjct: 240 GLHIYDPENR---LTPKIS-FPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKL 295
Query: 674 LMKL 677
+++L
Sbjct: 296 ILQL 299
>gi|32967266 neurofibromin 2 isoform 2 [Homo sapiens]
Length = 590
Score = 53.5 bits (127), Expect = 6e-07
Identities = 54/244 (22%), Positives = 104/244 (42%), Gaps = 23/244 (9%)
Query: 439 WPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL-KGFYT 497
W ++ ++ + D +E P F P E+++ + + F + + +L + Y
Sbjct: 74 WLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYC 133
Query: 498 APDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNRILHEY 557
P+A ++ LAS +Q YG+Y+ HK+GFL +E L + + W RI Y
Sbjct: 134 PPEASVL-LASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWY 192
Query: 558 KNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYVGVNIK 617
+E + + +L+ ++ YG +F + N K + +GV+
Sbjct: 193 -----AEHRGRARDEAEMEYLKIAQDLEMYGVNYF--------AIRNKKGTELLLGVDAL 239
Query: 618 GLHLLNMETKALLISLKYGCFMW----QLGDTDTCFQIHSMENKMSFIVHTKQAGLVVKL 673
GLH+ + E + ++ K F W + +D F I ++ K+ V KL
Sbjct: 240 GLHIYDPENR---LTPKIS-FPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKL 295
Query: 674 LMKL 677
+++L
Sbjct: 296 ILQL 299
>gi|32451486 neurofibromin 2 isoform 2 [Homo sapiens]
Length = 590
Score = 53.5 bits (127), Expect = 6e-07
Identities = 54/244 (22%), Positives = 104/244 (42%), Gaps = 23/244 (9%)
Query: 439 WPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL-KGFYT 497
W ++ ++ + D +E P F P E+++ + + F + + +L + Y
Sbjct: 74 WLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYC 133
Query: 498 APDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNRILHEY 557
P+A ++ LAS +Q YG+Y+ HK+GFL +E L + + W RI Y
Sbjct: 134 PPEASVL-LASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWY 192
Query: 558 KNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYVGVNIK 617
+E + + +L+ ++ YG +F + N K + +GV+
Sbjct: 193 -----AEHRGRARDEAEMEYLKIAQDLEMYGVNYF--------AIRNKKGTELLLGVDAL 239
Query: 618 GLHLLNMETKALLISLKYGCFMW----QLGDTDTCFQIHSMENKMSFIVHTKQAGLVVKL 673
GLH+ + E + ++ K F W + +D F I ++ K+ V KL
Sbjct: 240 GLHIYDPENR---LTPKIS-FPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKL 295
Query: 674 LMKL 677
+++L
Sbjct: 296 ILQL 299
>gi|4557795 neurofibromin 2 isoform 1 [Homo sapiens]
Length = 595
Score = 53.5 bits (127), Expect = 6e-07
Identities = 54/244 (22%), Positives = 104/244 (42%), Gaps = 23/244 (9%)
Query: 439 WPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL-KGFYT 497
W ++ ++ + D +E P F P E+++ + + F + + +L + Y
Sbjct: 74 WLKMDKKVLDHDVSKEEPVTFHFLAKFYPENAEEELVQEITQHLFFLQVKKQILDEKIYC 133
Query: 498 APDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNRILHEY 557
P+A ++ LAS +Q YG+Y+ HK+GFL +E L + + W RI Y
Sbjct: 134 PPEASVL-LASYAVQAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWY 192
Query: 558 KNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYVGVNIK 617
+E + + +L+ ++ YG +F + N K + +GV+
Sbjct: 193 -----AEHRGRARDEAEMEYLKIAQDLEMYGVNYF--------AIRNKKGTELLLGVDAL 239
Query: 618 GLHLLNMETKALLISLKYGCFMW----QLGDTDTCFQIHSMENKMSFIVHTKQAGLVVKL 673
GLH+ + E + ++ K F W + +D F I ++ K+ V KL
Sbjct: 240 GLHIYDPENR---LTPKIS-FPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKL 295
Query: 674 LMKL 677
+++L
Sbjct: 296 ILQL 299
>gi|4506467 radixin [Homo sapiens]
Length = 583
Score = 53.1 bits (126), Expect = 8e-07
Identities = 41/189 (21%), Positives = 83/189 (43%), Gaps = 13/189 (6%)
Query: 439 WPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLLKGFYTA 498
W ++ ++T D ++E P F R P +V +++ + + F + + +L
Sbjct: 58 WLKLNKKVTQQDVKKENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYC 117
Query: 499 PDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNRILHEYK 558
P + LAS +Q YG+Y + HK G+L + L + + K W RI + ++
Sbjct: 118 PPETAVLLASYAVQAKYGDYNKEIHKPGYLANDRLLPQRVLEQHKLTKEQWEERIQNWHE 177
Query: 559 NLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYVGVNIKG 618
G+ +E ++ +L+ ++ YG +F N K +++GV+ G
Sbjct: 178 E---HRGMLREDSMME--YLKIAQDLEMYGVNYF--------EIKNKKGTELWLGVDALG 224
Query: 619 LHLLNMETK 627
L++ + K
Sbjct: 225 LNIYEHDDK 233
>gi|156938343 talin 2 [Homo sapiens]
Length = 2542
Score = 53.1 bits (126), Expect = 8e-07
Identities = 37/155 (23%), Positives = 72/155 (46%), Gaps = 13/155 (8%)
Query: 476 DPLAILILFDEARYNLLKGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKS 535
DP+ + +L+ +AR ++L G + K QI +G + KHK GFL +LK
Sbjct: 210 DPVQLNLLYVQARDDILNGSHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFL---DLKE 266
Query: 536 IVPVTKLKSKAPHWTNRILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQ 595
+P +K + RI E+KN + ++ +++ + TYG +FF
Sbjct: 267 FLPKEYIKQRGAE--KRIFQEHKNCGEMSEIEAKV-----KYVKLARSLRTYGVSFF--- 316
Query: 596 IFTKASPSNHKVIPVYVGVNIKGLHLLNMETKALL 630
+ + +K++P +G+ + ++ +TK +L
Sbjct: 317 LVKEKMKGKNKLVPRLLGITKDSVMRVDEKTKEVL 351
>gi|4505257 moesin [Homo sapiens]
Length = 577
Score = 52.8 bits (125), Expect = 1e-06
Identities = 41/186 (22%), Positives = 82/186 (44%), Gaps = 19/186 (10%)
Query: 439 WPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLLKGFYTA 498
W ++ ++T D ++E+P LF R P +V +++ + + F + + +L
Sbjct: 58 WLKLNKKVTAQDVRKESPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYC 117
Query: 499 PDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNRIL---H 555
P + LAS +Q YG++ + HK G+L + L + + K W RI
Sbjct: 118 PPETAVLLASYAVQSKYGDFNKEVHKSGYLAGDKLLPQRVLEQHKLNKDQWEERIQVWHE 177
Query: 556 EYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYVGVN 615
E++ + + V + +L+ ++ YG +F S N K +++GV+
Sbjct: 178 EHRGMLREDAVLE--------YLKIAQDLEMYGVNYF--------SIKNKKGSELWLGVD 221
Query: 616 IKGLHL 621
GL++
Sbjct: 222 ALGLNI 227
>gi|223029410 talin 1 [Homo sapiens]
Length = 2541
Score = 52.4 bits (124), Expect = 1e-06
Identities = 36/155 (23%), Positives = 74/155 (47%), Gaps = 14/155 (9%)
Query: 476 DPLAILILFDEARYNLLKGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKS 535
DP+ + +L+ +AR ++L G + K A QI +G + +KHK GFL +LK
Sbjct: 208 DPVQLNLLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAGFL---DLKD 264
Query: 536 IVPVTKLKSKAPHWTNRILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQ 595
+P +K K +I +KN + ++ +++ + TYG +FF
Sbjct: 265 FLPKEYVKQKG---ERKIFQAHKNCGQMSEIEAKVR-----YVKLARSLKTYGVSFF--- 313
Query: 596 IFTKASPSNHKVIPVYVGVNIKGLHLLNMETKALL 630
+ + +K++P +G+ + + ++ +TK ++
Sbjct: 314 LVKEKMKGKNKLVPRLLGITKECVMRVDEKTKEVI 348
>gi|32967514 neurofibromin 2 isoform 7 [Homo sapiens]
Length = 507
Score = 52.4 bits (124), Expect = 1e-06
Identities = 57/230 (24%), Positives = 97/230 (42%), Gaps = 32/230 (13%)
Query: 452 QRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLLKGFYTAPDAKLITLASLLL 511
+R+ P+ F R V + E+E E IL DE Y P+A ++ LAS +
Sbjct: 15 KRKQPKTFTVRIVTMDAEMEFNCEVKKQIL---DEK-------IYCPPEASVL-LASYAV 63
Query: 512 QIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNRILHEYKNLSTSEGVSKEMH 571
Q YG+Y+ HK+GFL +E L + + W RI Y +E +
Sbjct: 64 QAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWY-----AEHRGRARD 118
Query: 572 HLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYVGVNIKGLHLLNMETKALLI 631
+ +L+ ++ YG +F + N K + +GV+ GLH+ + E + +
Sbjct: 119 EAEMEYLKIAQDLEMYGVNYF--------AIRNKKGTELLLGVDALGLHIYDPENR---L 167
Query: 632 SLKYGCFMW----QLGDTDTCFQIHSMENKMSFIVHTKQAGLVVKLLMKL 677
+ K F W + +D F I ++ K+ V KL+++L
Sbjct: 168 TPKIS-FPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQL 216
>gi|32967264 neurofibromin 2 isoform 7 [Homo sapiens]
Length = 507
Score = 52.4 bits (124), Expect = 1e-06
Identities = 57/230 (24%), Positives = 97/230 (42%), Gaps = 32/230 (13%)
Query: 452 QRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLLKGFYTAPDAKLITLASLLL 511
+R+ P+ F R V + E+E E IL DE Y P+A ++ LAS +
Sbjct: 15 KRKQPKTFTVRIVTMDAEMEFNCEVKKQIL---DEK-------IYCPPEASVL-LASYAV 63
Query: 512 QIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNRILHEYKNLSTSEGVSKEMH 571
Q YG+Y+ HK+GFL +E L + + W RI Y +E +
Sbjct: 64 QAKYGDYDPSVHKRGFLAQEELLPKRVINLYQMTPEMWEERITAWY-----AEHRGRARD 118
Query: 572 HLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYVGVNIKGLHLLNMETKALLI 631
+ +L+ ++ YG +F + N K + +GV+ GLH+ + E + +
Sbjct: 119 EAEMEYLKIAQDLEMYGVNYF--------AIRNKKGTELLLGVDALGLHIYDPENR---L 167
Query: 632 SLKYGCFMW----QLGDTDTCFQIHSMENKMSFIVHTKQAGLVVKLLMKL 677
+ K F W + +D F I ++ K+ V KL+++L
Sbjct: 168 TPKIS-FPWNEIRNISYSDKEFTIKPLDKKIDVFKFNSSKLRVNKLILQL 216
>gi|32967262 neurofibromin 2 isoform 6 [Homo sapiens]
Length = 549
Score = 50.1 bits (118), Expect = 7e-06
Identities = 50/209 (23%), Positives = 92/209 (44%), Gaps = 23/209 (11%)
Query: 474 IEDPLAILILFDEARYNLL-KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEEN 532
I+D +A L + + + +L + Y P+A ++ LAS +Q YG+Y+ HK+GFL +E
Sbjct: 68 IKDTVAWLKMDKKVKKQILDEKIYCPPEASVL-LASYAVQAKYGDYDPSVHKRGFLAQEE 126
Query: 533 LKSIVPVTKLKSKAPHWTNRILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFF 592
L + + W RI Y +E + + +L+ ++ YG +F
Sbjct: 127 LLPKRVINLYQMTPEMWEERITAWY-----AEHRGRARDEAEMEYLKIAQDLEMYGVNYF 181
Query: 593 TGQIFTKASPSNHKVIPVYVGVNIKGLHLLNMETKALLISLKYGCFMW----QLGDTDTC 648
+ N K + +GV+ GLH+ + E + ++ K F W + +D
Sbjct: 182 --------AIRNKKGTELLLGVDALGLHIYDPENR---LTPKIS-FPWNEIRNISYSDKE 229
Query: 649 FQIHSMENKMSFIVHTKQAGLVVKLLMKL 677
F I ++ K+ V KL+++L
Sbjct: 230 FTIKPLDKKIDVFKFNSSKLRVNKLILQL 258
>gi|161702986 ezrin [Homo sapiens]
Length = 586
Score = 47.8 bits (112), Expect = 3e-05
Identities = 39/189 (20%), Positives = 83/189 (43%), Gaps = 13/189 (6%)
Query: 439 WPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLLKGFYTA 498
W ++ +++ + ++E P F R P +V +++ + + F + + +L
Sbjct: 58 WLKLDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYC 117
Query: 499 PDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNRILHEYK 558
P + L S +Q +G+Y + HK G+L+ E L + + K W +RI +
Sbjct: 118 PPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWH- 176
Query: 559 NLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYVGVNIKG 618
+ G+ K+ L+ +L+ ++ YG +F N K +++GV+ G
Sbjct: 177 --AEHRGMLKDNAMLE--YLKIAQDLEMYGINYF--------EIKNKKGTDLWLGVDALG 224
Query: 619 LHLLNMETK 627
L++ + K
Sbjct: 225 LNIYEKDDK 233
>gi|21614499 ezrin [Homo sapiens]
Length = 586
Score = 47.8 bits (112), Expect = 3e-05
Identities = 39/189 (20%), Positives = 83/189 (43%), Gaps = 13/189 (6%)
Query: 439 WPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLLKGFYTA 498
W ++ +++ + ++E P F R P +V +++ + + F + + +L
Sbjct: 58 WLKLDKKVSAQEVRKENPLQFKFRAKFYPEDVAEELIQDITQKLFFLQVKEGILSDEIYC 117
Query: 499 PDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNRILHEYK 558
P + L S +Q +G+Y + HK G+L+ E L + + K W +RI +
Sbjct: 118 PPETAVLLGSYAVQAKFGDYNKEVHKSGYLSSERLIPQRVMDQHKLTRDQWEDRIQVWH- 176
Query: 559 NLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYVGVNIKG 618
+ G+ K+ L+ +L+ ++ YG +F N K +++GV+ G
Sbjct: 177 --AEHRGMLKDNAMLE--YLKIAQDLEMYGINYF--------EIKNKKGTDLWLGVDALG 224
Query: 619 LHLLNMETK 627
L++ + K
Sbjct: 225 LNIYEKDDK 233
>gi|110815813 ankyrin repeat and FYVE domain containing 1 isoform 1
[Homo sapiens]
Length = 1170
Score = 47.4 bits (111), Expect = 5e-05
Identities = 27/84 (32%), Positives = 45/84 (53%), Gaps = 2/84 (2%)
Query: 283 YGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGR 342
+G E + LLE G N N + + +P+H A H I+Q+L++HP+ ++ D+QG
Sbjct: 781 WGLEETVQCLLEFG-ANVNAQDAEGRTPIHVAISSQHGVIIQLLVSHPDIHLNVRDRQGL 839
Query: 343 SPLNICEENKQNNWEEAAKLLKEA 366
+P C +NN A L +E+
Sbjct: 840 TPF-ACAMTFKNNKSAEAILKRES 862
Score = 29.6 bits (65), Expect = 9.7
Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 292 LLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPL 345
LL+ G NPN+ + + +PLH + G+ + LL + D + D +G + L
Sbjct: 353 LLQAG-ANPNMQDSKGRTPLHVSIMAGNEYVFSQLLQCKQLDLELKDHEGSTAL 405
>gi|116534990 ankyrin-like protein 1 [Homo sapiens]
Length = 1119
Score = 46.6 bits (109), Expect = 8e-05
Identities = 28/87 (32%), Positives = 48/87 (55%), Gaps = 6/87 (6%)
Query: 285 KVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSP 344
++E+ + LL +G NPNL N + +PLH A G + E++++LL H D ++ + G +
Sbjct: 110 QIESVKFLLSRG-ANPNLRNFNMMAPLHIAVQGMNNEVMKVLLEHRTIDVNLEGENGNTA 168
Query: 345 LNI-CEENKQNNWEEAAKLLKEAINKP 370
+ I C N EA ++L + KP
Sbjct: 169 VIIACTTNN----SEALQILLKKGAKP 191
Score = 35.8 bits (81), Expect = 0.14
Identities = 30/106 (28%), Positives = 48/106 (45%), Gaps = 14/106 (13%)
Query: 284 GKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRS 343
G + +++L+ + L+ ++ LHFAA GHA+ V +LL+H D + QQ S
Sbjct: 525 GYTQTMKVILDTNLKCTDRLDEDGNTALHFAAREGHAKAVALLLSH-NADIVLNKQQA-S 582
Query: 344 PLNICEENKQ----------NNWEEAAKLLKEAINKPYEKVRIYRM 379
L++ NK+ W+E K+ N P K I M
Sbjct: 583 FLHLALHNKRKEVVLTIIRSKRWDECLKIFSH--NSPGNKCPITEM 626
Score = 31.6 bits (70), Expect = 2.6
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Query: 283 YGKVEATRILLEKGKCNPNLLNGQLS--SPLHFAAGGGHAEIVQILL 327
YG++ + LL+ L G L +PLH AA GH ++VQ+LL
Sbjct: 456 YGRINTCQRLLQDISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLLL 502
>gi|24233530 ankyrin repeat domain 44 [Homo sapiens]
Length = 919
Score = 45.1 bits (105), Expect = 2e-04
Identities = 36/132 (27%), Positives = 62/132 (46%), Gaps = 9/132 (6%)
Query: 284 GKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRS 343
G VE +LL KG N N + + LH+AA GH ++V +L+NH + D++G +
Sbjct: 126 GHVEMVNLLLAKG-ANINAFDKKDRRALHWAAYMGHLDVVALLINH-GAEVTCKDKKGYT 183
Query: 344 PLNICEENKQNNWEEAAKLLKEAINKPYEKVRIYRMDGSYRSVELKHGNNTTVQQIME-G 402
PL+ N Q N ++K +N E I + + +G + V ++++ G
Sbjct: 184 PLHAAASNGQIN------VVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYG 237
Query: 403 MRLSQETQQYFT 414
++Q FT
Sbjct: 238 ANVNQPNNNGFT 249
Score = 36.2 bits (82), Expect = 0.10
Identities = 22/66 (33%), Positives = 35/66 (53%), Gaps = 2/66 (3%)
Query: 283 YGKVEATRILLEKGKCN-PNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQG 341
YG + +LLE+ +G SPLH AA GH + +++LL D I D++G
Sbjct: 517 YGHRQCLELLLERTNSGFEESDSGATKSPLHLAAYNGHHQALEVLL-QSLVDLDIRDEKG 575
Query: 342 RSPLNI 347
R+ L++
Sbjct: 576 RTALDL 581
Score = 33.9 bits (76), Expect = 0.52
Identities = 23/85 (27%), Positives = 37/85 (43%), Gaps = 2/85 (2%)
Query: 284 GKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRS 343
G E +L+ G N + +PLH A E VQ+L+ H D + D+ ++
Sbjct: 27 GDAEIIELLILSG-ARVNAKDNMWLTPLHRAVASRSEEAVQVLIKH-SADVNARDKNWQT 84
Query: 344 PLNICEENKQNNWEEAAKLLKEAIN 368
PL++ NK E L ++N
Sbjct: 85 PLHVAAANKAVKCAEVIIPLLSSVN 109
Score = 33.5 bits (75), Expect = 0.67
Identities = 18/49 (36%), Positives = 26/49 (53%)
Query: 299 NPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 347
N N N +PLHFAA H + LL + D +I + G+SPL++
Sbjct: 239 NVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHM 287
Score = 33.1 bits (74), Expect = 0.88
Identities = 29/95 (30%), Positives = 47/95 (49%), Gaps = 10/95 (10%)
Query: 284 GKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHA----EIVQILLNHPETDRHITDQ 339
G E ++LLE+ + + + + +PLH+AA GHA E++Q+ L+ E D D
Sbjct: 689 GHEECVQMLLEQ-EVSILCKDSRGRTPLHYAAARGHATWLSELLQMALS--EEDCCFKDN 745
Query: 340 QGRSPLNICEENKQNNWEEA---AKLLKEAINKPY 371
QG +PL+ N N E K ++ I P+
Sbjct: 746 QGYTPLHWACYNGNENCIEVLLEQKCFRKFIGNPF 780
Score = 31.2 bits (69), Expect = 3.3
Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 1/41 (2%)
Query: 311 LHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEEN 351
LH AA GG+ E ++ LL D H D+ GR+PL+ N
Sbjct: 384 LHAAAAGGNVECIK-LLQSSGADFHKKDKCGRTPLHYAAAN 423
Score = 30.0 bits (66), Expect = 7.5
Identities = 19/68 (27%), Positives = 36/68 (52%), Gaps = 3/68 (4%)
Query: 287 EATRIL--LEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQG-RS 343
EAT L L + NP++ + + + +H+AA GH + +++LL + +D +S
Sbjct: 485 EATLCLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQCLELLLERTNSGFEESDSGATKS 544
Query: 344 PLNICEEN 351
PL++ N
Sbjct: 545 PLHLAAYN 552
>gi|34304381 inversin isoform a [Homo sapiens]
Length = 1065
Score = 44.7 bits (104), Expect = 3e-04
Identities = 26/79 (32%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
Query: 284 GKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRS 343
G V +L CN + +PLH+AA GHA+IV +LL ++ +D QG +
Sbjct: 232 GNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGAT 291
Query: 344 PLNICEENKQNNWEEAAKL 362
PL+ Q+N+ E K+
Sbjct: 292 PLHYA---AQSNFAETVKV 307
Score = 38.9 bits (89), Expect = 0.016
Identities = 20/60 (33%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Query: 284 GKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRS 343
G + +LLE+ K + Q ++PLH+AA AE V++ L HP + +D +GR+
Sbjct: 266 GHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSV-KDDSDLEGRT 324
Score = 38.1 bits (87), Expect = 0.027
Identities = 26/80 (32%), Positives = 45/80 (56%), Gaps = 5/80 (6%)
Query: 284 GKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRS 343
G + +IL+E K NPN+ + +PL AA GG+ + +L+ + D +I D++GR+
Sbjct: 434 GNADVCQILIEN-KINPNVQDYAGRTPLQCAAYGGYINCMAVLMEN-NADPNIQDKEGRT 491
Query: 344 PLNICEENKQNNWEEAAKLL 363
L+ + N + +A KLL
Sbjct: 492 ALH---WSCNNGYLDAIKLL 508
Score = 35.4 bits (80), Expect = 0.18
Identities = 20/53 (37%), Positives = 34/53 (64%), Gaps = 1/53 (1%)
Query: 293 LEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPL 345
L KG +L++ S LH+AA GG+A++ QIL+ + + + ++ D GR+PL
Sbjct: 409 LIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIEN-KINPNVQDYAGRTPL 460
>gi|34304379 inversin isoform b [Homo sapiens]
Length = 895
Score = 44.7 bits (104), Expect = 3e-04
Identities = 26/79 (32%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
Query: 284 GKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRS 343
G V +L CN + +PLH+AA GHA+IV +LL ++ +D QG +
Sbjct: 232 GNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGAT 291
Query: 344 PLNICEENKQNNWEEAAKL 362
PL+ Q+N+ E K+
Sbjct: 292 PLHYA---AQSNFAETVKV 307
Score = 38.9 bits (89), Expect = 0.016
Identities = 20/60 (33%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Query: 284 GKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRS 343
G + +LLE+ K + Q ++PLH+AA AE V++ L HP + +D +GR+
Sbjct: 266 GHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSV-KDDSDLEGRT 324
Score = 38.1 bits (87), Expect = 0.027
Identities = 26/80 (32%), Positives = 45/80 (56%), Gaps = 5/80 (6%)
Query: 284 GKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRS 343
G + +IL+E K NPN+ + +PL AA GG+ + +L+ + D +I D++GR+
Sbjct: 434 GNADVCQILIEN-KINPNVQDYAGRTPLQCAAYGGYINCMAVLMEN-NADPNIQDKEGRT 491
Query: 344 PLNICEENKQNNWEEAAKLL 363
L+ + N + +A KLL
Sbjct: 492 ALH---WSCNNGYLDAIKLL 508
Score = 35.4 bits (80), Expect = 0.18
Identities = 20/53 (37%), Positives = 34/53 (64%), Gaps = 1/53 (1%)
Query: 293 LEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPL 345
L KG +L++ S LH+AA GG+A++ QIL+ + + + ++ D GR+PL
Sbjct: 409 LIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIEN-KINPNVQDYAGRTPL 460
>gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase [Homo sapiens]
Length = 1327
Score = 43.5 bits (101), Expect = 7e-04
Identities = 27/68 (39%), Positives = 35/68 (51%), Gaps = 2/68 (2%)
Query: 282 KYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQG 341
K G +E + L N L G+ S+PLHFAAG +V+ LL+H D H D+ G
Sbjct: 659 KAGDLETVKQLCSSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHH-GADVHAKDKGG 717
Query: 342 RSPL-NIC 348
PL N C
Sbjct: 718 LVPLHNAC 725
Score = 42.0 bits (97), Expect = 0.002
Identities = 42/142 (29%), Positives = 60/142 (42%), Gaps = 13/142 (9%)
Query: 224 KADTCIYNPLFGSDLQYTNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKY 283
K D CI G+D N K ++ L P + + +K + ++ +
Sbjct: 294 KIDVCIVLLQHGADPNIRNTDGKSALD----LADPSAKAVLTGEYKKDELLEAA----RS 345
Query: 284 GKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRS 343
G E LL N + +G+ S+PLH AAG IVQ+LL H D H D+ G
Sbjct: 346 GNEEKLMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQH-GADVHAKDKGGLV 404
Query: 344 PL-NICEENKQNNWEEAAKLLK 364
PL N C ++E LLK
Sbjct: 405 PLHNAC---SYGHYEVTELLLK 423
Score = 39.3 bits (90), Expect = 0.012
Identities = 25/66 (37%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 284 GKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRS 343
G V + L++ N + G+ SSPLHFAAG G ++V+ LL + H D G
Sbjct: 193 GDVSRVKRLVDAANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLL-QMGANVHARDDGGLI 251
Query: 344 PL-NIC 348
PL N C
Sbjct: 252 PLHNAC 257
Score = 35.4 bits (80), Expect = 0.18
Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 2/65 (3%)
Query: 283 YGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGR 342
YG E T +LL+ G C N ++ +PLH AA E+ +LL+H D + + G+
Sbjct: 412 YGHYEVTELLLKHGAC-VNAMDLWQFTPLHEAASKNRVEVCSLLLSH-GADPTLVNCHGK 469
Query: 343 SPLNI 347
S +++
Sbjct: 470 SAVDM 474
Score = 33.9 bits (76), Expect = 0.52
Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 6/54 (11%)
Query: 298 CNPNLLN-----GQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLN 346
C P +N G+ S+PLH AAG + E+ + LL H D + D+ G PL+
Sbjct: 823 CTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEH-GADVNAQDKGGLIPLH 875
Score = 33.5 bits (75), Expect = 0.67
Identities = 21/67 (31%), Positives = 36/67 (53%), Gaps = 2/67 (2%)
Query: 283 YGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGR 342
+G E +LL +G +PN + +PLH AA G ++ +LL H D +I + G+
Sbjct: 259 FGHAEVVSLLLCQG-ADPNARDNWNYTPLHEAAIKGKIDVCIVLLQH-GADPNIRNTDGK 316
Query: 343 SPLNICE 349
S L++ +
Sbjct: 317 SALDLAD 323
Score = 32.7 bits (73), Expect = 1.1
Identities = 16/43 (37%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 287 EATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNH 329
+ T +LL KG N N N +PLH AA H +++++L H
Sbjct: 539 QVTELLLRKG-ANVNEKNKDFMTPLHVAAERAHNDVMEVLHKH 580
Score = 30.0 bits (66), Expect = 7.5
Identities = 33/120 (27%), Positives = 53/120 (44%), Gaps = 10/120 (8%)
Query: 283 YGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGR 342
Y +V LL G G L PLH A GH E+ ++L+ H ++ D
Sbjct: 694 YNRVSVVEYLLHHGADVHAKDKGGLV-PLHNACSYGHYEVAELLVRH-GASVNVADLWKF 751
Query: 343 SPLNICEENKQNNWEEAAKLLKEAINKPYEKVRIYRMDGSYRSVELKHGNNTTVQQIMEG 402
+PL+ E + +E LLK + P +K R DG+ ++L +T +Q ++ G
Sbjct: 752 TPLH--EAAAKGKYEICKLLLKHGAD-PTKKNR----DGN-TPLDLVKEGDTDIQDLLRG 803
Score = 30.0 bits (66), Expect = 7.5
Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 2/64 (3%)
Query: 283 YGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGR 342
Y +E LLE G + N + PLH AA GH +I +L+ + T + TD+
Sbjct: 847 YNNLEVAEYLLEHG-ADVNAQDKGGLIPLHNAASYGHVDIAALLIKY-NTCVNATDKWAF 904
Query: 343 SPLN 346
+PL+
Sbjct: 905 TPLH 908
>gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase 2 [Homo sapiens]
Length = 1166
Score = 43.5 bits (101), Expect = 7e-04
Identities = 31/84 (36%), Positives = 41/84 (48%), Gaps = 5/84 (5%)
Query: 282 KYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQG 341
K G VE + L N + G+ S+PLHFAAG +V+ LL H D H D+ G
Sbjct: 501 KAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQH-GADVHAKDKGG 559
Query: 342 RSPL-NICEENKQNNWEEAAKLLK 364
PL N C ++E A L+K
Sbjct: 560 LVPLHNAC---SYGHYEVAELLVK 580
Score = 38.5 bits (88), Expect = 0.021
Identities = 26/66 (39%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
Query: 284 GKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRS 343
G E LL N + +G+ S+PLH AAG +IVQ+LL H D H D+
Sbjct: 188 GNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQH-GADVHAKDKGDLV 246
Query: 344 PL-NIC 348
PL N C
Sbjct: 247 PLHNAC 252
Score = 37.7 bits (86), Expect = 0.036
Identities = 25/66 (37%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 284 GKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRS 343
G VE + L+ K N G+ S+PLHFAAG G ++V+ LL + + D G
Sbjct: 35 GDVERVKRLVTPEKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQN-GANVQARDDGGLI 93
Query: 344 PL-NIC 348
PL N C
Sbjct: 94 PLHNAC 99
Score = 33.1 bits (74), Expect = 0.88
Identities = 22/64 (34%), Positives = 32/64 (50%), Gaps = 2/64 (3%)
Query: 283 YGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGR 342
+G+ + LL+ G +G L PLH A GHAE+V +LL H D + D
Sbjct: 68 FGRKDVVEYLLQNGANVQARDDGGLI-PLHNACSFGHAEVVNLLLRH-GADPNARDNWNY 125
Query: 343 SPLN 346
+PL+
Sbjct: 126 TPLH 129
Score = 32.3 bits (72), Expect = 1.5
Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
Query: 282 KYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQG 341
K G + + L N G+ S+PLH AAG + E+ + LL H D + D+ G
Sbjct: 654 KKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQH-GADVNAQDKGG 712
Query: 342 RSPLN 346
PL+
Sbjct: 713 LIPLH 717
Score = 32.0 bits (71), Expect = 2.0
Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 2/67 (2%)
Query: 283 YGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGR 342
+G E +LL G +PN + +PLH AA G ++ +LL H + I + GR
Sbjct: 101 FGHAEVVNLLLRHG-ADPNARDNWNYTPLHEAAIKGKIDVCIVLLQH-GAEPTIRNTDGR 158
Query: 343 SPLNICE 349
+ L++ +
Sbjct: 159 TALDLAD 165
Score = 31.2 bits (69), Expect = 3.3
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 1/47 (2%)
Query: 283 YGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNH 329
YG E T +L++ G C N ++ +PLH AA E+ +LL++
Sbjct: 254 YGHYEVTELLVKHGAC-VNAMDLWQFTPLHEAASKNRVEVCSLLLSY 299
Score = 30.4 bits (67), Expect = 5.7
Identities = 33/120 (27%), Positives = 52/120 (43%), Gaps = 10/120 (8%)
Query: 283 YGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGR 342
Y +V LL+ G G L PLH A GH E+ ++L+ H ++ D
Sbjct: 536 YNRVSVVEYLLQHGADVHAKDKGGLV-PLHNACSYGHYEVAELLVKHGAV-VNVADLWKF 593
Query: 343 SPLNICEENKQNNWEEAAKLLKEAINKPYEKVRIYRMDGSYRSVELKHGNNTTVQQIMEG 402
+PL+ E E KLL + P +K R DG+ ++L +T +Q ++ G
Sbjct: 594 TPLH---EAAAKGKYEICKLLLQHGADPTKKNR----DGN-TPLDLVKDGDTDIQDLLRG 645
Score = 29.6 bits (65), Expect = 9.7
Identities = 17/56 (30%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
Query: 291 ILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLN 346
+LL KG N N + +PLH A+ H ++V++++ H E + D G++ L+
Sbjct: 385 LLLRKG-ANINEKTKEFLTPLHVASEKAHNDVVEVVVKH-EAKVNALDNLGQTSLH 438
>gi|96975023 ankyrin repeat and death domain containing 1A [Homo
sapiens]
Length = 522
Score = 42.0 bits (97), Expect = 0.002
Identities = 23/80 (28%), Positives = 47/80 (58%), Gaps = 5/80 (6%)
Query: 284 GKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRS 343
G + +R+L+ G C N+++ Q +SPLH A +V++L+N ++D + D + ++
Sbjct: 269 GSEDVSRVLIHAGGC-ANVVDHQGASPLHLAVRHNFPALVRLLIN-SDSDVNAVDNRQQT 326
Query: 344 PLNICEENKQNNWEEAAKLL 363
PL++ E+ W++ A +L
Sbjct: 327 PLHLAAEHA---WQDIADML 343
Score = 31.6 bits (70), Expect = 2.6
Identities = 15/47 (31%), Positives = 31/47 (65%), Gaps = 1/47 (2%)
Query: 282 KYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLN 328
++G+++A L+ G C+ N+ + + ++ LH AAG GH ++Q L++
Sbjct: 168 EHGQLDALDFLVGSG-CDHNVKDKEGNTALHLAAGRGHMAVLQRLVD 213
>gi|23510377 KN motif and ankyrin repeat domains 1 isoform b [Homo
sapiens]
Length = 1194
Score = 41.6 bits (96), Expect = 0.002
Identities = 46/193 (23%), Positives = 79/193 (40%), Gaps = 20/193 (10%)
Query: 169 AQSHFIPALFRP--SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKAD 226
+Q IPA+ + E I +V+ G +LH S + L L+ AD
Sbjct: 969 SQKSAIPAMVGDYIAAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLD-AD 1027
Query: 227 TCI--------YNPLFGSDLQYTN-RVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSS 277
C Y P+ + L D ++ FG G + + Q ++
Sbjct: 1028 VCNVDHQNKAGYTPIMLAALAAVEAEKDMRIVEELFGCG-----DVNAKASQAGQTALML 1082
Query: 278 VTEDKYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHIT 337
+G+++ + LL G + N+ + + S+ L A+ GH EIV++LL P + H+
Sbjct: 1083 AVS--HGRIDMVKGLLACG-ADVNIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLE 1139
Query: 338 DQQGRSPLNICEE 350
D G + L+I E
Sbjct: 1140 DNDGSTALSIALE 1152
Score = 32.7 bits (73), Expect = 1.1
Identities = 17/56 (30%), Positives = 29/56 (51%)
Query: 274 SMSSVTEDKYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNH 329
S + + ++G VE ++LL + CN +L + S+ L A GH +I +L H
Sbjct: 1110 STALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAH 1165
>gi|64464726 KN motif and ankyrin repeat domains 1 isoform a [Homo
sapiens]
Length = 1352
Score = 41.6 bits (96), Expect = 0.002
Identities = 46/193 (23%), Positives = 79/193 (40%), Gaps = 20/193 (10%)
Query: 169 AQSHFIPALFRP--SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKAD 226
+Q IPA+ + E I +V+ G +LH S + L L+ AD
Sbjct: 1127 SQKSAIPAMVGDYIAAFEAISPDVLRYVINLADGNGNTALHYSVSHSNFEIVKLLLD-AD 1185
Query: 227 TCI--------YNPLFGSDLQYTN-RVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSS 277
C Y P+ + L D ++ FG G + + Q ++
Sbjct: 1186 VCNVDHQNKAGYTPIMLAALAAVEAEKDMRIVEELFGCG-----DVNAKASQAGQTALML 1240
Query: 278 VTEDKYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHIT 337
+G+++ + LL G + N+ + + S+ L A+ GH EIV++LL P + H+
Sbjct: 1241 AVS--HGRIDMVKGLLACG-ADVNIQDDEGSTALMCASEHGHVEIVKLLLAQPGCNGHLE 1297
Query: 338 DQQGRSPLNICEE 350
D G + L+I E
Sbjct: 1298 DNDGSTALSIALE 1310
Score = 32.7 bits (73), Expect = 1.1
Identities = 17/56 (30%), Positives = 29/56 (51%)
Query: 274 SMSSVTEDKYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNH 329
S + + ++G VE ++LL + CN +L + S+ L A GH +I +L H
Sbjct: 1268 STALMCASEHGHVEIVKLLLAQPGCNGHLEDNDGSTALSIALEAGHKDIAVLLYAH 1323
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,471,978
Number of Sequences: 37866
Number of extensions: 1120569
Number of successful extensions: 3767
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 88
Number of HSP's successfully gapped in prelim test: 138
Number of HSP's that attempted gapping in prelim test: 3039
Number of HSP's gapped (non-prelim): 836
length of query: 688
length of database: 18,247,518
effective HSP length: 109
effective length of query: 579
effective length of database: 14,120,124
effective search space: 8175551796
effective search space used: 8175551796
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.