Guide to the Human Genome
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Search of human proteins with 13540557

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13540557 G protein-coupled receptor 63 [Homo sapiens]
         (419 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|221139879 G protein-coupled receptor 63 [Homo sapiens]             843   0.0  
gi|13540557 G protein-coupled receptor 63 [Homo sapiens]              843   0.0  
gi|31083315 G protein-coupled receptor 45 [Homo sapiens]              404   e-113
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]         123   3e-28
gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]         123   3e-28
gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]         123   3e-28
gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]         123   3e-28
gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]         123   3e-28
gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]         123   3e-28
gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]        114   2e-25
gi|24476016 G protein-coupled receptor 161 isoform 2 [Homo sapiens]   109   4e-24
gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]           104   1e-22
gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]            104   1e-22
gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens]         102   5e-22
gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens]          102   5e-22
gi|5174593 melatonin receptor 1A [Homo sapiens]                       102   5e-22
gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]      100   2e-21
gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens]   100   3e-21
gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens]   100   3e-21
gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens]    100   3e-21
gi|15150803 opsin 4 isoform 1 [Homo sapiens]                          100   3e-21
gi|4758474 G protein-coupled receptor 10 [Homo sapiens]               100   4e-21
gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo sapi...    97   3e-20
gi|110618256 trace amine associated receptor 9 [Homo sapiens]          97   4e-20
gi|10835175 5-hydroxytryptamine (serotonin) receptor 2A [Homo sa...    96   5e-20
gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]     96   6e-20
gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]     96   6e-20
gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]     96   6e-20
gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]     96   6e-20
gi|5174595 melatonin receptor 1B [Homo sapiens]                        96   6e-20

>gi|221139879 G protein-coupled receptor 63 [Homo sapiens]
          Length = 419

 Score =  843 bits (2177), Expect = 0.0
 Identities = 419/419 (100%), Positives = 419/419 (100%)

Query: 1   MVFSAVLTAFHTGTSNTTFVVYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT 60
           MVFSAVLTAFHTGTSNTTFVVYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT
Sbjct: 1   MVFSAVLTAFHTGTSNTTFVVYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT 60

Query: 61  VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL 120
           VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL
Sbjct: 61  VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL 120

Query: 121 ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF 180
           ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF
Sbjct: 121 ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF 180

Query: 181 LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ 240
           LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ
Sbjct: 181 LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ 240

Query: 241 AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF 300
           AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF
Sbjct: 241 AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF 300

Query: 301 QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC 360
           QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC
Sbjct: 301 QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC 360

Query: 361 YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV 419
           YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV
Sbjct: 361 YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV 419


>gi|13540557 G protein-coupled receptor 63 [Homo sapiens]
          Length = 419

 Score =  843 bits (2177), Expect = 0.0
 Identities = 419/419 (100%), Positives = 419/419 (100%)

Query: 1   MVFSAVLTAFHTGTSNTTFVVYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT 60
           MVFSAVLTAFHTGTSNTTFVVYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT
Sbjct: 1   MVFSAVLTAFHTGTSNTTFVVYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT 60

Query: 61  VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL 120
           VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL
Sbjct: 61  VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL 120

Query: 121 ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF 180
           ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF
Sbjct: 121 ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF 180

Query: 181 LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ 240
           LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ
Sbjct: 181 LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ 240

Query: 241 AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF 300
           AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF
Sbjct: 241 AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF 300

Query: 301 QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC 360
           QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC
Sbjct: 301 QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC 360

Query: 361 YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV 419
           YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV
Sbjct: 361 YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV 419


>gi|31083315 G protein-coupled receptor 45 [Homo sapiens]
          Length = 372

 Score =  404 bits (1039), Expect = e-113
 Identities = 190/344 (55%), Positives = 262/344 (76%)

Query: 76  LNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNM 135
           L  PL+I+L+ +M+ +  V FLGN VVC++VYQ+ AMRSAIN+LLA+LAF+D++L++  M
Sbjct: 29  LPAPLRISLAIVMLLMTVVGFLGNTVVCIIVYQRPAMRSAINLLLATLAFSDIMLSLCCM 88

Query: 136 PFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQRQDKLNPYRA 195
           PF  VT++T RW FG  FCR+SA  +W FV+EGVAILLIIS+DRFLIIVQRQDKLNP RA
Sbjct: 89  PFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLIIVQRQDKLNPRRA 148

Query: 196 KVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFFIPF 255
           KV+IAVSW  SFC+A P   G   +++P+RAPQCV GYT  P  +AYV+ + +  FF PF
Sbjct: 149 KVIIAVSWVLSFCIAGPSLTGWTLVEVPARAPQCVLGYTELPADRAYVVTLVVAVFFAPF 208

Query: 256 LVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSIDMGFKTRAFTT 315
            V+L ++M ILNT+R NA+R+H+  + + L Q ++ GL  LQR  Q+S+D+ FKT+AFTT
Sbjct: 209 GVMLCAYMCILNTVRKNAVRVHNQSDSLDLRQLTRAGLRRLQRQQQVSVDLSFKTKAFTT 268

Query: 316 ILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYLKSALNPLIYYWRI 375
           ILILF  F +CW P + YSL++ FS+ FY   +F+  ST +LWL YLKS  NP++Y WRI
Sbjct: 269 ILILFVGFSLCWLPHSVYSLLSVFSQRFYCGSSFYATSTCVLWLSYLKSVFNPIVYCWRI 328

Query: 376 KKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV 419
           KKF +AC++++P++F+ LP++P   +RRI+PS VYVC E+++ V
Sbjct: 329 KKFREACIELLPQTFQILPKVPERIRRRIQPSTVYVCNENQSAV 372


>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
          Length = 359

 Score =  123 bits (309), Expect = 3e-28
 Identities = 89/321 (27%), Positives = 154/321 (47%), Gaps = 33/321 (10%)

Query: 81  QITLSAIMIFILFVSFLGNLVVCLMV-YQKAAMRSAINILLASLAFADMLLAVLNMPFAL 139
           ++ L   +  ++ ++ LGNL+V + V + +   +   N  + SLAFAD+L++VL MPF  
Sbjct: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78

Query: 140 VTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII----VQRQDKLNPYRA 195
           + ++   WI+G+ FC V      L     +  L  IS+DR+  I    +  ++K+ P R 
Sbjct: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138

Query: 196 KVLIAVSWATSFCVAF-PLAVGNPDLQIPSRAPQCVFGYTTNPGY------QAYVILISL 248
            +++   W     ++F P+  G  ++ I     +  F   +N  Y      + Y I  S+
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198

Query: 249 ISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSID--- 305
           ++F+IPFL+++ ++  I  T + +A +I             + G  S  RP   S D   
Sbjct: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQI---------QMLQRAGASSESRP--QSADQHS 247

Query: 306 ---MGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYL 362
              M  +T+A  T+ I+   F +CWAPF   ++V  F  +        ++ T  LWL Y+
Sbjct: 248 THRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPG----QVWTAFLWLGYI 303

Query: 363 KSALNPLIYYWRIKKFHDACL 383
            S LNP +Y +  K F  A L
Sbjct: 304 NSGLNPFLYAFLNKSFRRAFL 324


>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
          Length = 428

 Score =  123 bits (309), Expect = 3e-28
 Identities = 89/321 (27%), Positives = 154/321 (47%), Gaps = 33/321 (10%)

Query: 81  QITLSAIMIFILFVSFLGNLVVCLMV-YQKAAMRSAINILLASLAFADMLLAVLNMPFAL 139
           ++ L   +  ++ ++ LGNL+V + V + +   +   N  + SLAFAD+L++VL MPF  
Sbjct: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78

Query: 140 VTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII----VQRQDKLNPYRA 195
           + ++   WI+G+ FC V      L     +  L  IS+DR+  I    +  ++K+ P R 
Sbjct: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138

Query: 196 KVLIAVSWATSFCVAF-PLAVGNPDLQIPSRAPQCVFGYTTNPGY------QAYVILISL 248
            +++   W     ++F P+  G  ++ I     +  F   +N  Y      + Y I  S+
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198

Query: 249 ISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSID--- 305
           ++F+IPFL+++ ++  I  T + +A +I             + G  S  RP   S D   
Sbjct: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQI---------QMLQRAGASSESRP--QSADQHS 247

Query: 306 ---MGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYL 362
              M  +T+A  T+ I+   F +CWAPF   ++V  F  +        ++ T  LWL Y+
Sbjct: 248 THRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPG----QVWTAFLWLGYI 303

Query: 363 KSALNPLIYYWRIKKFHDACL 383
            S LNP +Y +  K F  A L
Sbjct: 304 NSGLNPFLYAFLNKSFRRAFL 324


>gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]
          Length = 360

 Score =  123 bits (309), Expect = 3e-28
 Identities = 89/321 (27%), Positives = 154/321 (47%), Gaps = 33/321 (10%)

Query: 81  QITLSAIMIFILFVSFLGNLVVCLMV-YQKAAMRSAINILLASLAFADMLLAVLNMPFAL 139
           ++ L   +  ++ ++ LGNL+V + V + +   +   N  + SLAFAD+L++VL MPF  
Sbjct: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78

Query: 140 VTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII----VQRQDKLNPYRA 195
           + ++   WI+G+ FC V      L     +  L  IS+DR+  I    +  ++K+ P R 
Sbjct: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138

Query: 196 KVLIAVSWATSFCVAF-PLAVGNPDLQIPSRAPQCVFGYTTNPGY------QAYVILISL 248
            +++   W     ++F P+  G  ++ I     +  F   +N  Y      + Y I  S+
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198

Query: 249 ISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSID--- 305
           ++F+IPFL+++ ++  I  T + +A +I             + G  S  RP   S D   
Sbjct: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQI---------QMLQRAGASSESRP--QSADQHS 247

Query: 306 ---MGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYL 362
              M  +T+A  T+ I+   F +CWAPF   ++V  F  +        ++ T  LWL Y+
Sbjct: 248 THRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPG----QVWTAFLWLGYI 303

Query: 363 KSALNPLIYYWRIKKFHDACL 383
            S LNP +Y +  K F  A L
Sbjct: 304 NSGLNPFLYAFLNKSFRRAFL 324


>gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]
          Length = 387

 Score =  123 bits (309), Expect = 3e-28
 Identities = 89/321 (27%), Positives = 154/321 (47%), Gaps = 33/321 (10%)

Query: 81  QITLSAIMIFILFVSFLGNLVVCLMV-YQKAAMRSAINILLASLAFADMLLAVLNMPFAL 139
           ++ L   +  ++ ++ LGNL+V + V + +   +   N  + SLAFAD+L++VL MPF  
Sbjct: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78

Query: 140 VTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII----VQRQDKLNPYRA 195
           + ++   WI+G+ FC V      L     +  L  IS+DR+  I    +  ++K+ P R 
Sbjct: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138

Query: 196 KVLIAVSWATSFCVAF-PLAVGNPDLQIPSRAPQCVFGYTTNPGY------QAYVILISL 248
            +++   W     ++F P+  G  ++ I     +  F   +N  Y      + Y I  S+
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198

Query: 249 ISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSID--- 305
           ++F+IPFL+++ ++  I  T + +A +I             + G  S  RP   S D   
Sbjct: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQI---------QMLQRAGASSESRP--QSADQHS 247

Query: 306 ---MGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYL 362
              M  +T+A  T+ I+   F +CWAPF   ++V  F  +        ++ T  LWL Y+
Sbjct: 248 THRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPG----QVWTAFLWLGYI 303

Query: 363 KSALNPLIYYWRIKKFHDACL 383
            S LNP +Y +  K F  A L
Sbjct: 304 NSGLNPFLYAFLNKSFRRAFL 324


>gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]
          Length = 378

 Score =  123 bits (309), Expect = 3e-28
 Identities = 89/321 (27%), Positives = 154/321 (47%), Gaps = 33/321 (10%)

Query: 81  QITLSAIMIFILFVSFLGNLVVCLMV-YQKAAMRSAINILLASLAFADMLLAVLNMPFAL 139
           ++ L   +  ++ ++ LGNL+V + V + +   +   N  + SLAFAD+L++VL MPF  
Sbjct: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78

Query: 140 VTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII----VQRQDKLNPYRA 195
           + ++   WI+G+ FC V      L     +  L  IS+DR+  I    +  ++K+ P R 
Sbjct: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138

Query: 196 KVLIAVSWATSFCVAF-PLAVGNPDLQIPSRAPQCVFGYTTNPGY------QAYVILISL 248
            +++   W     ++F P+  G  ++ I     +  F   +N  Y      + Y I  S+
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198

Query: 249 ISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSID--- 305
           ++F+IPFL+++ ++  I  T + +A +I             + G  S  RP   S D   
Sbjct: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQI---------QMLQRAGASSESRP--QSADQHS 247

Query: 306 ---MGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYL 362
              M  +T+A  T+ I+   F +CWAPF   ++V  F  +        ++ T  LWL Y+
Sbjct: 248 THRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPG----QVWTAFLWLGYI 303

Query: 363 KSALNPLIYYWRIKKFHDACL 383
            S LNP +Y +  K F  A L
Sbjct: 304 NSGLNPFLYAFLNKSFRRAFL 324


>gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]
          Length = 388

 Score =  123 bits (309), Expect = 3e-28
 Identities = 89/321 (27%), Positives = 154/321 (47%), Gaps = 33/321 (10%)

Query: 81  QITLSAIMIFILFVSFLGNLVVCLMV-YQKAAMRSAINILLASLAFADMLLAVLNMPFAL 139
           ++ L   +  ++ ++ LGNL+V + V + +   +   N  + SLAFAD+L++VL MPF  
Sbjct: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78

Query: 140 VTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII----VQRQDKLNPYRA 195
           + ++   WI+G+ FC V      L     +  L  IS+DR+  I    +  ++K+ P R 
Sbjct: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138

Query: 196 KVLIAVSWATSFCVAF-PLAVGNPDLQIPSRAPQCVFGYTTNPGY------QAYVILISL 248
            +++   W     ++F P+  G  ++ I     +  F   +N  Y      + Y I  S+
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198

Query: 249 ISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSID--- 305
           ++F+IPFL+++ ++  I  T + +A +I             + G  S  RP   S D   
Sbjct: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQI---------QMLQRAGASSESRP--QSADQHS 247

Query: 306 ---MGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYL 362
              M  +T+A  T+ I+   F +CWAPF   ++V  F  +        ++ T  LWL Y+
Sbjct: 248 THRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPG----QVWTAFLWLGYI 303

Query: 363 KSALNPLIYYWRIKKFHDACL 383
            S LNP +Y +  K F  A L
Sbjct: 304 NSGLNPFLYAFLNKSFRRAFL 324


>gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]
          Length = 402

 Score =  114 bits (285), Expect = 2e-25
 Identities = 90/340 (26%), Positives = 154/340 (45%), Gaps = 57/340 (16%)

Query: 81  QITLSAIMIFILFVSFLGNLVVCLMV-YQKAAMRSAINILLASLAFADMLLAVLNMPFAL 139
           ++ L   +  ++ ++ LGNL+V + V + +   +   N  + SLAFAD+L++VL MPF  
Sbjct: 19  KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78

Query: 140 VTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII----VQRQDKLNPYRA 195
           + ++   WI+G+ FC V      L     +  L  IS+DR+  I    +  ++K+ P R 
Sbjct: 79  IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138

Query: 196 KVLIAVSWATSFCVAF-PLAVGNPDLQI-------------------------PSRAPQC 229
            +++   W     ++F P+  G  ++ I                          S +  C
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQNSNSTYC 198

Query: 230 VFGYTTNPGYQAYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQAS 289
           VF        + Y I  S+++F+IPFL+++ ++  I  T + +A +I             
Sbjct: 199 VFMVN-----KPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI---------QMLQ 244

Query: 290 KLGLMSLQRPFQMSID------MGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHF 343
           + G  S  RP   S D      M  +T+A  T+ I+   F +CWAPF   ++V  F  + 
Sbjct: 245 RAGASSESRP--QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYT 302

Query: 344 YYQHNFFEISTWLLWLCYLKSALNPLIYYWRIKKFHDACL 383
                  ++ T  LWL Y+ S LNP +Y +  K F  A L
Sbjct: 303 VPG----QVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFL 338


>gi|24476016 G protein-coupled receptor 161 isoform 2 [Homo sapiens]
          Length = 529

 Score =  109 bits (273), Expect = 4e-24
 Identities = 79/300 (26%), Positives = 136/300 (45%), Gaps = 22/300 (7%)

Query: 86  AIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFALVTILTT 145
           AI++  +FV  LGNLV+ + +Y+K+ + +  N  + SL  ++ LL+VL +PF + + +  
Sbjct: 33  AIIVITIFVC-LGNLVIVVTLYKKSYLLTLSNKFVFSLTLSNFLLSVLVLPFVVTSSIRR 91

Query: 146 RWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQRQ---DKLNPYRAKVLIAVS 202
            WIFG  +C  SA+ + L     +  L +I+IDR+  ++       K+   RA + +   
Sbjct: 92  EWIFGVVWCNFSALLYLLISSASMLTLGVIAIDRYYAVLYPMVYPMKITGNRAVMALVYI 151

Query: 203 WATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFFIPFLVILYSF 262
           W  S     P   G   ++       CV  +   PGY A+     +     PFLV+L  +
Sbjct: 152 WLHSLIGCLPPLFGWSSVEFDEFKWMCVAAWHREPGYTAF---WQIWCALFPFLVMLVCY 208

Query: 263 MGILNTLRHNALRIHSYPEGICLSQASKLGLM----------SLQRPFQMSIDMGFKTRA 312
             I    R  A ++H     I    A + G            S +  FQ  +    + +A
Sbjct: 209 GFIFRVARVKARKVHCGTVVIVEEDAQRTGRKNSSTSTSSSGSRRNAFQGVVYSANQCKA 268

Query: 313 FTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFF-EISTWLLWLCYLKSALNPLIY 371
             TIL++   F+V W P+    +V   S+  + + +    + TW  WL +  +  +PLIY
Sbjct: 269 LITILVVLGAFMVTWGPY----MVVIASEALWGKSSVSPSLETWATWLSFASAVCHPLIY 324


>gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]
          Length = 397

 Score =  104 bits (260), Expect = 1e-22
 Identities = 83/331 (25%), Positives = 149/331 (45%), Gaps = 53/331 (16%)

Query: 51  MAPTGL-SSLTVNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQK 109
           MAP G  SS  ++STA               +IT++ ++  ++ ++  GN+VVCL V   
Sbjct: 1   MAPNGTASSFCLDSTAC--------------KITITVVLAVLILITVAGNVVVCLAVGLN 46

Query: 110 AAMRSAINILLASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGV 169
             +R+  N  + SLA  D+LL +L +PF+ +  L+ +W FGK FC +      +     +
Sbjct: 47  RRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASI 106

Query: 170 AILLIISIDRFLIIVQRQDKLNPYRAKVL-----IAVSWATSFCVAFPLAVGNPDLQIPS 224
             L +IS+DR+  +      ++P R  VL     +A+S    + ++  L+  +  L   S
Sbjct: 107 LNLFMISLDRYCAV------MDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNS 160

Query: 225 RAPQCVFGYTTN----PGYQAYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYP 280
           R       +TT+       + Y ++  L++F++P L++  ++  I    R  A RI+   
Sbjct: 161 RNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINH-- 218

Query: 281 EGICLSQASKLGLMSLQRPFQMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFS 340
             I   +A+ +                 + +A  T+  +   FI+CW P+ T  +     
Sbjct: 219 --ISSWKAATIR----------------EHKATVTLAAVMGAFIICWFPYFTAFVYRGLR 260

Query: 341 KHFYYQHNFFEISTWLLWLCYLKSALNPLIY 371
                      +   +LWL Y  SALNP++Y
Sbjct: 261 GDDAINE---VLEAIVLWLGYANSALNPILY 288


>gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]
          Length = 359

 Score =  104 bits (260), Expect = 1e-22
 Identities = 83/331 (25%), Positives = 149/331 (45%), Gaps = 53/331 (16%)

Query: 51  MAPTGL-SSLTVNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQK 109
           MAP G  SS  ++STA               +IT++ ++  ++ ++  GN+VVCL V   
Sbjct: 1   MAPNGTASSFCLDSTAC--------------KITITVVLAVLILITVAGNVVVCLAVGLN 46

Query: 110 AAMRSAINILLASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGV 169
             +R+  N  + SLA  D+LL +L +PF+ +  L+ +W FGK FC +      +     +
Sbjct: 47  RRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASI 106

Query: 170 AILLIISIDRFLIIVQRQDKLNPYRAKVL-----IAVSWATSFCVAFPLAVGNPDLQIPS 224
             L +IS+DR+  +      ++P R  VL     +A+S    + ++  L+  +  L   S
Sbjct: 107 LNLFMISLDRYCAV------MDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNS 160

Query: 225 RAPQCVFGYTTN----PGYQAYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYP 280
           R       +TT+       + Y ++  L++F++P L++  ++  I    R  A RI+   
Sbjct: 161 RNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINH-- 218

Query: 281 EGICLSQASKLGLMSLQRPFQMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFS 340
             I   +A+ +                 + +A  T+  +   FI+CW P+ T  +     
Sbjct: 219 --ISSWKAATIR----------------EHKATVTLAAVMGAFIICWFPYFTAFVYRGLR 260

Query: 341 KHFYYQHNFFEISTWLLWLCYLKSALNPLIY 371
                      +   +LWL Y  SALNP++Y
Sbjct: 261 GDDAINE---VLEAIVLWLGYANSALNPILY 288


>gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens]
          Length = 311

 Score =  102 bits (255), Expect = 5e-22
 Identities = 73/296 (24%), Positives = 133/296 (44%), Gaps = 26/296 (8%)

Query: 81  QITL-SAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFAL 139
           QI L +A    I+  S +GN+VV  ++     MR+  N  L +LAFA+  +A  N     
Sbjct: 31  QIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNF 90

Query: 140 VTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQ-RQDKLNPYRAKVL 198
              +   W +G F+C+    F    V   +  +  ++ DR++ I+   Q +L+    KV+
Sbjct: 91  TYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVV 150

Query: 199 IAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPG---YQAYVILISLISFFIPF 255
           I V W  +  +AFP    +    +PSR   C+  +  +P     + Y I ++++ +F+P 
Sbjct: 151 ICVIWVLALLLAFPQGYYSTTETMPSRV-VCMIEWPEHPNKIYEKVYHICVTVLIYFLPL 209

Query: 256 LVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSIDMGFKTRAFTT 315
           LVI Y++  +                GI L  +   G  S +   Q+S     K +    
Sbjct: 210 LVIGYAYTVV----------------GITLWASEIPGDSSDRYHEQVSA----KRKVVKM 249

Query: 316 ILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYLKSALNPLIY 371
           ++++   F +CW PF  + L+   +   Y +    ++   ++WL    +  NP+IY
Sbjct: 250 MIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIY 305


>gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens]
          Length = 407

 Score =  102 bits (255), Expect = 5e-22
 Identities = 73/296 (24%), Positives = 133/296 (44%), Gaps = 26/296 (8%)

Query: 81  QITL-SAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFAL 139
           QI L +A    I+  S +GN+VV  ++     MR+  N  L +LAFA+  +A  N     
Sbjct: 31  QIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNF 90

Query: 140 VTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQ-RQDKLNPYRAKVL 198
              +   W +G F+C+    F    V   +  +  ++ DR++ I+   Q +L+    KV+
Sbjct: 91  TYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVV 150

Query: 199 IAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPG---YQAYVILISLISFFIPF 255
           I V W  +  +AFP    +    +PSR   C+  +  +P     + Y I ++++ +F+P 
Sbjct: 151 ICVIWVLALLLAFPQGYYSTTETMPSRV-VCMIEWPEHPNKIYEKVYHICVTVLIYFLPL 209

Query: 256 LVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSIDMGFKTRAFTT 315
           LVI Y++  +                GI L  +   G  S +   Q+S     K +    
Sbjct: 210 LVIGYAYTVV----------------GITLWASEIPGDSSDRYHEQVSA----KRKVVKM 249

Query: 316 ILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYLKSALNPLIY 371
           ++++   F +CW PF  + L+   +   Y +    ++   ++WL    +  NP+IY
Sbjct: 250 MIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIY 305


>gi|5174593 melatonin receptor 1A [Homo sapiens]
          Length = 350

 Score =  102 bits (255), Expect = 5e-22
 Identities = 79/300 (26%), Positives = 131/300 (43%), Gaps = 38/300 (12%)

Query: 80  LQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFAL 139
           L   L+ ++IF + V  LGNL+V L VY+   +R+A NI + SLA AD+++A+   P  L
Sbjct: 26  LASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVL 85

Query: 140 VTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQ--RQDKL-NPYRAK 196
           ++I    W  G   C+VS     L VI  +  +  I+I+R+  I    + DKL +   + 
Sbjct: 86  MSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSL 145

Query: 197 VLIAVSWATSFCVAFP-LAVGNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFFIPF 255
             + + W  +     P L  G   LQ   R   C F  + +    AY I + +  F +P 
Sbjct: 146 CYVLLIWLLTLAAVLPNLRAGT--LQYDPRIYSCTFAQSVS---SAYTIAVVVFHFLVPM 200

Query: 256 LVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSIDMGFKTRAFTT 315
           +++++ ++ I   +     R+   P+               ++P     D     R F T
Sbjct: 201 IIVIFCYLRIWILVLQVRQRVK--PD---------------RKPKLKPQDF----RNFVT 239

Query: 316 ILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLL----WLCYLKSALNPLIY 371
           + ++F +F +CWAP     L                I  WL     ++ Y  S LN +IY
Sbjct: 240 MFVVFVLFAICWAPLNFIGLAVASDPASMVP----RIPEWLFVASYYMAYFNSCLNAIIY 295


>gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]
          Length = 413

 Score =  100 bits (249), Expect = 2e-21
 Identities = 79/304 (25%), Positives = 141/304 (46%), Gaps = 29/304 (9%)

Query: 82  ITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFALVT 141
           I +S I++ I+F    GN++V   + +   +++  N  + SLA AD+++ +  +PF    
Sbjct: 38  IVMSLIVLAIVF----GNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAH 93

Query: 142 ILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIV---QRQDKLNPYRAKVL 198
           IL   W FG F+C        L V   +  L +I++DR+  I    + Q  L   +A+V+
Sbjct: 94  ILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVI 153

Query: 199 IAVSWATSFCVAF-PLAV----GNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFFI 253
           I + W  S   +F P+ +          I   A +    + TN   QAY I  S++SF++
Sbjct: 154 ILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTN---QAYAIASSIVSFYV 210

Query: 254 PFLVILYSFMGILNTLRHNALRIHSYPEGIC----LSQASKLGLM--SLQRPFQMSIDMG 307
           P +++++ +  +    +    +I    EG      LSQ  + G     L+R  +  +   
Sbjct: 211 PLVIMVFVYSRVFQEAKRQLQKIDK-SEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLK-- 267

Query: 308 FKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYLKSALN 367
            + +A  T+ I+   F +CW PF   ++V     +   +    E+   L W+ Y+ S  N
Sbjct: 268 -EHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRK----EVYILLNWIGYVNSGFN 322

Query: 368 PLIY 371
           PLIY
Sbjct: 323 PLIY 326


>gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens]
          Length = 432

 Score =  100 bits (248), Expect = 3e-21
 Identities = 90/319 (28%), Positives = 142/319 (44%), Gaps = 43/319 (13%)

Query: 81  QITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFALV 140
           ++ + +I+  I  ++  GN +V + V     +R   N L+ SLA AD+ +AV  MPF  V
Sbjct: 81  KVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSV 140

Query: 141 T-ILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQ------RQDKLNPY 193
           T ++  +WIFG FFC V      +     +  L +ISIDR+L I +      RQ+     
Sbjct: 141 TDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQN--GKC 198

Query: 194 RAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCV----FGYTTNPGYQAYVILISLI 249
            AK++++V W  S  +  P   G    Q  +    C+    FGYT         I  + +
Sbjct: 199 MAKMILSV-WLLSASITLPPLFG--WAQNVNDDKVCLISQDFGYT---------IYSTAV 246

Query: 250 SFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKL---GLMSLQRPFQMSIDM 306
           +F+IP  V+L+ +  I    R +A + H +P    +   S +   G++ LQ+  +   ++
Sbjct: 247 AFYIPMSVMLFMYYQIYKAARKSAAK-HKFPGFPRVEPDSVIALNGIVKLQKEVEECANL 305

Query: 307 G------------FK--TRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEI 352
                        FK   +A TT+ I+   F VCW PF   S    F            +
Sbjct: 306 SRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWV 365

Query: 353 STWLLWLCYLKSALNPLIY 371
               LWL Y  S +NP IY
Sbjct: 366 ERTFLWLGYANSLINPFIY 384


>gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens]
          Length = 479

 Score =  100 bits (248), Expect = 3e-21
 Identities = 90/319 (28%), Positives = 142/319 (44%), Gaps = 43/319 (13%)

Query: 81  QITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFALV 140
           ++ + +I+  I  ++  GN +V + V     +R   N L+ SLA AD+ +AV  MPF  V
Sbjct: 81  KVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSV 140

Query: 141 T-ILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQ------RQDKLNPY 193
           T ++  +WIFG FFC V      +     +  L +ISIDR+L I +      RQ+     
Sbjct: 141 TDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQN--GKC 198

Query: 194 RAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCV----FGYTTNPGYQAYVILISLI 249
            AK++++V W  S  +  P   G    Q  +    C+    FGYT         I  + +
Sbjct: 199 MAKMILSV-WLLSASITLPPLFG--WAQNVNDDKVCLISQDFGYT---------IYSTAV 246

Query: 250 SFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKL---GLMSLQRPFQMSIDM 306
           +F+IP  V+L+ +  I    R +A + H +P    +   S +   G++ LQ+  +   ++
Sbjct: 247 AFYIPMSVMLFMYYQIYKAARKSAAK-HKFPGFPRVEPDSVIALNGIVKLQKEVEECANL 305

Query: 307 G------------FK--TRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEI 352
                        FK   +A TT+ I+   F VCW PF   S    F            +
Sbjct: 306 SRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWV 365

Query: 353 STWLLWLCYLKSALNPLIY 371
               LWL Y  S +NP IY
Sbjct: 366 ERTFLWLGYANSLINPFIY 384


>gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens]
          Length = 445

 Score =  100 bits (248), Expect = 3e-21
 Identities = 90/319 (28%), Positives = 142/319 (44%), Gaps = 43/319 (13%)

Query: 81  QITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFALV 140
           ++ + +I+  I  ++  GN +V + V     +R   N L+ SLA AD+ +AV  MPF  V
Sbjct: 81  KVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSV 140

Query: 141 T-ILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQ------RQDKLNPY 193
           T ++  +WIFG FFC V      +     +  L +ISIDR+L I +      RQ+     
Sbjct: 141 TDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQN--GKC 198

Query: 194 RAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCV----FGYTTNPGYQAYVILISLI 249
            AK++++V W  S  +  P   G    Q  +    C+    FGYT         I  + +
Sbjct: 199 MAKMILSV-WLLSASITLPPLFG--WAQNVNDDKVCLISQDFGYT---------IYSTAV 246

Query: 250 SFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKL---GLMSLQRPFQMSIDM 306
           +F+IP  V+L+ +  I    R +A + H +P    +   S +   G++ LQ+  +   ++
Sbjct: 247 AFYIPMSVMLFMYYQIYKAARKSAAK-HKFPGFPRVEPDSVIALNGIVKLQKEVEECANL 305

Query: 307 G------------FK--TRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEI 352
                        FK   +A TT+ I+   F VCW PF   S    F            +
Sbjct: 306 SRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWV 365

Query: 353 STWLLWLCYLKSALNPLIY 371
               LWL Y  S +NP IY
Sbjct: 366 ERTFLWLGYANSLINPFIY 384


>gi|15150803 opsin 4 isoform 1 [Homo sapiens]
          Length = 478

 Score =  100 bits (248), Expect = 3e-21
 Identities = 93/394 (23%), Positives = 166/394 (42%), Gaps = 34/394 (8%)

Query: 32  PPPFQHPD-LSPLLRYSFETMAPTGLSSLTVNSTAVPTTPAAFKSLNLPL---------Q 81
           P P Q P  ++     S+   + + +SSL    +  PT P  + +  +PL          
Sbjct: 11  PSPTQEPSCMATPAPPSWWDSSQSSISSLGRLPSISPTAPGTWAAAWVPLPTVDVPDHAH 70

Query: 82  ITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFALVT 141
            TL  +++ +     LGNL V     +  ++R+  N+ + +LA +D L++    P    +
Sbjct: 71  YTLGTVILLVGLTGMLGNLTVIYTFCRSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTS 130

Query: 142 ILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQRQDKL---NPYRAKVL 198
            L  +W+FG+  C   A    LF I  +  L  I++DR+L+I +        +  RA  +
Sbjct: 131 SLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRAAFV 190

Query: 199 IAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTT-NPGYQAYVILISLISFFIPFLV 257
           +   W  +   + P   G            C + Y +  P  +AY +L+    FF+P L+
Sbjct: 191 LLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLCCFVFFLPLLI 250

Query: 258 ILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSIDMGFKTRAFTTIL 317
           I+Y ++ I   +R     + ++  G C      L     QR    S     + +    +L
Sbjct: 251 IIYCYIFIFRAIRETGRALQTF--GACKGNGESL----WQRQRLQS-----ECKMAKIML 299

Query: 318 ILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYLKSAL-NPLIYYWRIK 376
           ++  +F++ WAP++  +LVA       Y H      + +  +    SA+ NP+IY     
Sbjct: 300 LVILLFVLSWAPYSAVALVAFAG----YAHVLTPYMSSVPAVIAKASAIHNPIIYAITHP 355

Query: 377 KFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVY 410
           K+  A    +P     L  L G ++R  RP   Y
Sbjct: 356 KYRVAIAQHLP----CLGVLLGVSRRHSRPYPSY 385


>gi|4758474 G protein-coupled receptor 10 [Homo sapiens]
          Length = 370

 Score = 99.8 bits (247), Expect = 4e-21
 Identities = 80/332 (24%), Positives = 146/332 (43%), Gaps = 39/332 (11%)

Query: 63  STAVPTTPAA--FKSLNLPLQITLSAIMIF--ILFVSFLGNLVVCLMVYQKAAMRSAINI 118
           S A    PA   F+SL L  Q+    ++++  ++ V  +GN ++ L++ +   + +  N 
Sbjct: 38  SVAGADAPAVTPFQSLQLVHQLKGLIVLLYSVVVVVGLVGNCLLVLVIARVRRLHNVTNF 97

Query: 119 LLASLAFADMLLAVLNMPFALVTILTTR-WIFGKFFCRVSAMFFWLFVIEGVAILLIISI 177
           L+ +LA +D+L+    +P  L      R W+FG   C +      + V   V  L  I++
Sbjct: 98  LIGNLALSDVLMCTACVPLTLAYAFEPRGWVFGGGLCHLVFFLQPVTVYVSVFTLTTIAV 157

Query: 178 DRFLIIVQRQDKLNPYRAKVLIAVS-------WATSFCVAFPLAVGNPDLQI-PSRAPQC 229
           DR++++V      +P R ++ + +S       WA S  +A P AV    +++ P     C
Sbjct: 158 DRYVVLV------HPLRRRISLRLSAYAVLAIWALSAVLALPAAVHTYHVELKPHDVRLC 211

Query: 230 V-FGYTTNPGYQAYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQA 288
             F  +     Q Y   + L+++ +P LVIL S++ +   LR+  +         C++Q+
Sbjct: 212 EEFWGSQERQRQLYAWGLLLVTYLLPLLVILLSYVRVSVKLRNRVVPG-------CVTQS 264

Query: 289 SKLGLMSLQRPFQMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHN 348
                       Q   D   + R F  ++++  VF VCW P   ++L+     H    + 
Sbjct: 265 ------------QADWDRARRRRTFCLLVVVVVVFAVCWLPLHVFNLLRDLDPHAIDPYA 312

Query: 349 FFEISTWLLWLCYLKSALNPLIYYWRIKKFHD 380
           F  +     WL    +  NP IY W    F +
Sbjct: 313 FGLVQLLCHWLAMSSACYNPFIYAWLHDSFRE 344


>gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo
           sapiens]
          Length = 440

 Score = 97.1 bits (240), Expect = 3e-20
 Identities = 78/316 (24%), Positives = 149/316 (47%), Gaps = 20/316 (6%)

Query: 84  LSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFALVTIL 143
           ++A +  ++ ++   N ++  ++  + A+R+  N  L SL  +D+++ ++ MP A++  L
Sbjct: 29  VAAALCVVIALTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNAL 88

Query: 144 TTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII---VQRQDKLNPYRAKVLIA 200
             RW+  +  C +   F  +     +  L +IS+DR+L+I   ++ + ++ P RA  L+ 
Sbjct: 89  YGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPLRALALVL 148

Query: 201 VSWATSFCVAF-PLAVGNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFFIPFLVIL 259
            +W+ +   +F PL +G  +L     A   V G         +V++ S ++FF+P   I 
Sbjct: 149 GAWSLAALASFLPLLLGWHEL---GHARPPVPGQCRLLASLPFVLVASGLTFFLPSGAIC 205

Query: 260 YSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSID---MGFK-----TR 311
           +++  IL   R  A+++ S   G+    +  L +    RP   S D   +  K      +
Sbjct: 206 FTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSRRLATKHSRKALK 265

Query: 312 AFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYLKSALNPLIY 371
           A  T+ IL  +F V W PF   ++V             F++   L WL Y  S +NP+IY
Sbjct: 266 ASLTLGILLGMFFVTWLPFFVANIVQAVCD--CISPGLFDV---LTWLGYCNSTMNPIIY 320

Query: 372 YWRIKKFHDACLDMMP 387
              ++ F  A    +P
Sbjct: 321 PLFMRDFKRALGRFLP 336


>gi|110618256 trace amine associated receptor 9 [Homo sapiens]
          Length = 348

 Score = 96.7 bits (239), Expect = 4e-20
 Identities = 81/294 (27%), Positives = 135/294 (45%), Gaps = 23/294 (7%)

Query: 84  LSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFALVTIL 143
           L A++ F   ++  GNL+V + +     + +  N L+ASLA AD L+ V  MPF+ V  +
Sbjct: 35  LYAVLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVRSV 94

Query: 144 TTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII---VQRQDKLNPYRAKVLIA 200
            + W FG  +C+    F   F    +  L  IS+DR++ +   +    K     + + I 
Sbjct: 95  ESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIV 154

Query: 201 VSWATSFCVAFPL---AVGNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFFIPFLV 257
           +SW  S   +F +         ++    A  CV G    P  Q +V+L  L+ FFIP + 
Sbjct: 155 LSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQA-PLNQNWVLLCFLL-FFIPNVA 212

Query: 258 ILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSIDMGFKTRAFTTIL 317
           +++ +  I    +H A +I S       SQA        +R  +       + +A  T+ 
Sbjct: 213 MVFIYSKIFLVAKHQARKIES-----TASQAQSSSESYKERVAKR------ERKAAKTLG 261

Query: 318 ILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYLKSALNPLIY 371
           I  A F+V W P+   +++  +  +F      +EI   L+W  Y  SA+NPLIY
Sbjct: 262 IAMAAFLVSWLPYLVDAVIDAY-MNFITPPYVYEI---LVWCVYYNSAMNPLIY 311


>gi|10835175 5-hydroxytryptamine (serotonin) receptor 2A [Homo
           sapiens]
          Length = 471

 Score = 96.3 bits (238), Expect = 5e-20
 Identities = 85/335 (25%), Positives = 151/335 (45%), Gaps = 28/335 (8%)

Query: 69  TPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADM 128
           +P+    L+L  +   + +   ++ ++  GN++V + V  +  +++A N  L SLA ADM
Sbjct: 62  SPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADM 121

Query: 129 LLAVLNMPFALVTIL-TTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII---V 184
           LL  L MP +++TIL   RW      C V      LF    +  L  IS+DR++ I   +
Sbjct: 122 LLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPI 181

Query: 185 QRQDKLNPYRAKVLIAVSWATSFCVAFPLAV-GNPDLQIPSRAPQCVFGYTTNPGYQAYV 243
                 +  +A + I   W  S  ++ P+ V G  D     +   C+           +V
Sbjct: 182 HHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDN------FV 235

Query: 244 ILISLISFFIPFLVILYSFMGILNTLRHNA-LRIHSYPEGICLSQASKLGLMSL--QRPF 300
           ++ S +SFFIP  +++ ++   + +L+  A L +        L+  S L   SL  ++ F
Sbjct: 236 LIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLF 295

Query: 301 QMSI--------------DMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQ 346
           Q SI               +  + +A   + I+F +F+V W PF   +++A   K    +
Sbjct: 296 QRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNE 355

Query: 347 HNFFEISTWLLWLCYLKSALNPLIYYWRIKKFHDA 381
                +    +W+ YL SA+NPL+Y    K +  A
Sbjct: 356 DVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSA 390


>gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]
          Length = 455

 Score = 95.9 bits (237), Expect = 6e-20
 Identities = 89/369 (24%), Positives = 159/369 (43%), Gaps = 39/369 (10%)

Query: 76  LNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNM 135
           +N+   I L  I+  ++    LGN++V L V     + S  +  + +LA AD+LL    +
Sbjct: 21  VNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVL 80

Query: 136 PFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII---VQRQDKLNP 192
           PF+ +  +   W FG+ FC + A    L     +  L IISIDR++ +   ++    +  
Sbjct: 81  PFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQ 140

Query: 193 YRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFF 252
            R  + +   WA S  ++     G    + P+   + +      PG   YV+  +L SF+
Sbjct: 141 RRGLMALLCVWALSLVISIGPLFG---WRQPAPEDETICQINEEPG---YVLFSALGSFY 194

Query: 253 IPFLVILYSF-----------MGILNTLRHN-------ALRIHSYPEGICLSQASKLGLM 294
           +P  +IL  +            G+ + L+ +        LRIH        + A   G+ 
Sbjct: 195 LPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN-----APAGGSGMA 249

Query: 295 SLQRPFQMSIDM---GFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFE 351
           S +     S+ +     + +A  T+ I+   F++CW PF     + +F   F      F+
Sbjct: 250 SAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFK 309

Query: 352 ISTWLLWLCYLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHT-KRRIRPSAVY 410
           I   + WL YL S +NP+IY    ++F  A  +++        Q   H     + P +  
Sbjct: 310 I---VFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHALGYTLHPPSQA 366

Query: 411 VCGEHRTVV 419
           V G+H+ +V
Sbjct: 367 VEGQHKDMV 375


>gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]
          Length = 466

 Score = 95.9 bits (237), Expect = 6e-20
 Identities = 89/369 (24%), Positives = 159/369 (43%), Gaps = 39/369 (10%)

Query: 76  LNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNM 135
           +N+   I L  I+  ++    LGN++V L V     + S  +  + +LA AD+LL    +
Sbjct: 21  VNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVL 80

Query: 136 PFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII---VQRQDKLNP 192
           PF+ +  +   W FG+ FC + A    L     +  L IISIDR++ +   ++    +  
Sbjct: 81  PFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQ 140

Query: 193 YRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFF 252
            R  + +   WA S  ++     G    + P+   + +      PG   YV+  +L SF+
Sbjct: 141 RRGLMALLCVWALSLVISIGPLFG---WRQPAPEDETICQINEEPG---YVLFSALGSFY 194

Query: 253 IPFLVILYSF-----------MGILNTLRHN-------ALRIHSYPEGICLSQASKLGLM 294
           +P  +IL  +            G+ + L+ +        LRIH        + A   G+ 
Sbjct: 195 LPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN-----APAGGSGMA 249

Query: 295 SLQRPFQMSIDM---GFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFE 351
           S +     S+ +     + +A  T+ I+   F++CW PF     + +F   F      F+
Sbjct: 250 SAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFK 309

Query: 352 ISTWLLWLCYLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHT-KRRIRPSAVY 410
           I   + WL YL S +NP+IY    ++F  A  +++        Q   H     + P +  
Sbjct: 310 I---VFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHALGYTLHPPSQA 366

Query: 411 VCGEHRTVV 419
           V G+H+ +V
Sbjct: 367 VEGQHKDMV 375


>gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]
          Length = 475

 Score = 95.9 bits (237), Expect = 6e-20
 Identities = 89/369 (24%), Positives = 159/369 (43%), Gaps = 39/369 (10%)

Query: 76  LNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNM 135
           +N+   I L  I+  ++    LGN++V L V     + S  +  + +LA AD+LL    +
Sbjct: 21  VNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVL 80

Query: 136 PFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII---VQRQDKLNP 192
           PF+ +  +   W FG+ FC + A    L     +  L IISIDR++ +   ++    +  
Sbjct: 81  PFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQ 140

Query: 193 YRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFF 252
            R  + +   WA S  ++     G    + P+   + +      PG   YV+  +L SF+
Sbjct: 141 RRGLMALLCVWALSLVISIGPLFG---WRQPAPEDETICQINEEPG---YVLFSALGSFY 194

Query: 253 IPFLVILYSF-----------MGILNTLRHN-------ALRIHSYPEGICLSQASKLGLM 294
           +P  +IL  +            G+ + L+ +        LRIH        + A   G+ 
Sbjct: 195 LPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN-----APAGGSGMA 249

Query: 295 SLQRPFQMSIDM---GFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFE 351
           S +     S+ +     + +A  T+ I+   F++CW PF     + +F   F      F+
Sbjct: 250 SAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFK 309

Query: 352 ISTWLLWLCYLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHT-KRRIRPSAVY 410
           I   + WL YL S +NP+IY    ++F  A  +++        Q   H     + P +  
Sbjct: 310 I---VFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHALGYTLHPPSQA 366

Query: 411 VCGEHRTVV 419
           V G+H+ +V
Sbjct: 367 VEGQHKDMV 375


>gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]
          Length = 429

 Score = 95.9 bits (237), Expect = 6e-20
 Identities = 89/369 (24%), Positives = 159/369 (43%), Gaps = 39/369 (10%)

Query: 76  LNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNM 135
           +N+   I L  I+  ++    LGN++V L V     + S  +  + +LA AD+LL    +
Sbjct: 21  VNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVL 80

Query: 136 PFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII---VQRQDKLNP 192
           PF+ +  +   W FG+ FC + A    L     +  L IISIDR++ +   ++    +  
Sbjct: 81  PFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQ 140

Query: 193 YRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFF 252
            R  + +   WA S  ++     G    + P+   + +      PG   YV+  +L SF+
Sbjct: 141 RRGLMALLCVWALSLVISIGPLFG---WRQPAPEDETICQINEEPG---YVLFSALGSFY 194

Query: 253 IPFLVILYSF-----------MGILNTLRHN-------ALRIHSYPEGICLSQASKLGLM 294
           +P  +IL  +            G+ + L+ +        LRIH        + A   G+ 
Sbjct: 195 LPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN-----APAGGSGMA 249

Query: 295 SLQRPFQMSIDM---GFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFE 351
           S +     S+ +     + +A  T+ I+   F++CW PF     + +F   F      F+
Sbjct: 250 SAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFK 309

Query: 352 ISTWLLWLCYLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHT-KRRIRPSAVY 410
           I   + WL YL S +NP+IY    ++F  A  +++        Q   H     + P +  
Sbjct: 310 I---VFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHALGYTLHPPSQA 366

Query: 411 VCGEHRTVV 419
           V G+H+ +V
Sbjct: 367 VEGQHKDMV 375


>gi|5174595 melatonin receptor 1B [Homo sapiens]
          Length = 362

 Score = 95.9 bits (237), Expect = 6e-20
 Identities = 79/292 (27%), Positives = 121/292 (41%), Gaps = 30/292 (10%)

Query: 84  LSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFALVTIL 143
           LSA++I    V  +GNL+V L V +   +R+A N+ L SLA AD+++A    P  LV I 
Sbjct: 43  LSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIF 102

Query: 144 TTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQRQDKLNPYR---AKVLIA 200
              W  G+  C+ SA    L VI  V  +  I+I+R+  I         YR     + I 
Sbjct: 103 YDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHIC 162

Query: 201 VSWATSFCVAFP-LAVGNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFFIPFLVIL 259
           + W  +     P   VG+  L+   R   C F  T +  Y A V+   +I F +P  V+ 
Sbjct: 163 LIWLLTVVALLPNFFVGS--LEYDPRIYSCTFIQTASTQYTAAVV---VIHFLLPIAVVS 217

Query: 260 YSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSIDMGFKTRAFTTILIL 319
           + ++ I   L   A R       +CL  +                      R+F T+ ++
Sbjct: 218 FCYLRIW-VLVLQARRKAKPESRLCLKPSD--------------------LRSFLTMFVV 256

Query: 320 FAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYLKSALNPLIY 371
           F +F +CWAP     L    +           +      L Y  S LN ++Y
Sbjct: 257 FVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVY 308


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.332    0.142    0.446 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,739,183
Number of Sequences: 37866
Number of extensions: 607719
Number of successful extensions: 3239
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 474
Number of HSP's successfully gapped in prelim test: 180
Number of HSP's that attempted gapping in prelim test: 2021
Number of HSP's gapped (non-prelim): 895
length of query: 419
length of database: 18,247,518
effective HSP length: 105
effective length of query: 314
effective length of database: 14,271,588
effective search space: 4481278632
effective search space used: 4481278632
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (22.0 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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