Search of human proteins with 13540513

Search of human proteins with 13540513

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13540513 oxysterol binding protein 2 isoform a [Homo
sapiens]
         (916 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens]     1858   0.0  
gi|4505531 oxysterol binding protein [Homo sapiens]                   949   0.0  
gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo sa...   335   1e-91
gi|21735584 oxysterol-binding protein-like protein 3 isoform d [...   284   3e-76
gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo sa...   283   5e-76
gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [H...   274   2e-73
gi|21450853 oxysterol-binding protein-like protein 2 isoform 2 [...   272   1e-72
gi|22035612 oxysterol-binding protein-like protein 6 isoform b [...   271   2e-72
gi|14210532 oxysterol-binding protein-like protein 6 isoform a [...   271   2e-72
gi|21735582 oxysterol-binding protein-like protein 3 isoform c [...   266   5e-71
gi|21735580 oxysterol-binding protein-like protein 3 isoform b [...   266   9e-71
gi|14149704 oxysterol-binding protein-like protein 3 isoform a [...   266   9e-71
gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens]   253   6e-67
gi|22547173 oxysterol binding protein-like 9 isoform d [Homo sap...   104   3e-22
gi|14149740 oxysterol-binding protein-like protein 5 isoform a [...   103   7e-22
gi|221136766 oxysterol-binding protein-like protein 5 isoform b ...   103   7e-22
gi|22035609 oxysterol-binding protein-like protein 5 isoform b [...   103   7e-22
gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]          102   1e-21
gi|20070331 oxysterol binding protein-like 9 isoform e [Homo sap...   102   2e-21
gi|19923812 oxysterol-binding protein-like protein 10 [Homo sapi...    99   1e-20
gi|22547176 oxysterol binding protein-like 9 isoform f [Homo sap...    97   5e-20
gi|51243032 oxysterol-binding protein-like protein 8 isoform b [...    93   1e-18
gi|18079218 oxysterol-binding protein-like protein 8 isoform a [...    93   1e-18
gi|54792084 pleckstrin homology domain containing, family A (pho...    87   5e-17
gi|194294543 alpha 3 type IV collagen binding protein isoform 3 ...    84   6e-16
gi|5031717 alpha 3 type IV collagen binding protein isoform 1 [H...    84   6e-16
gi|14165452 alpha 3 type IV collagen binding protein isoform 2 [...    82   2e-15
gi|14249174 pleckstrin homology domain containing, family A (pho...    78   3e-14
gi|22547171 oxysterol binding protein-like 9 isoform c [Homo sap...    58   4e-08
gi|22547169 oxysterol binding protein-like 9 isoform b [Homo sap...    58   4e-08

>gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens]
          Length = 916

 Score = 1858 bits (4813), Expect = 0.0
 Identities = 916/916 (100%), Positives = 916/916 (100%)

Query: 1   MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEP 60
           MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEP
Sbjct: 1   MGKAAAPSRGGGCGGRSRGLSSLFTVVPCLSCHTAAPGMSASTSGSGPEPKPQPQPVPEP 60

Query: 61  ERGPLSEQVSEAVSEAVPRSEPVSETTSEPEPGAGQPSELLQGSRPGSESSSGVGAGPFT 120
           ERGPLSEQVSEAVSEAVPRSEPVSETTSEPEPGAGQPSELLQGSRPGSESSSGVGAGPFT
Sbjct: 61  ERGPLSEQVSEAVSEAVPRSEPVSETTSEPEPGAGQPSELLQGSRPGSESSSGVGAGPFT 120

Query: 121 KAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL 180
           KAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL
Sbjct: 121 KAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPMSGTGTTSSAPLALL 180

Query: 181 PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDS 240
           PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDS
Sbjct: 181 PLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDS 240

Query: 241 CGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKS 300
           CGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKS
Sbjct: 241 CGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKS 300

Query: 301 ELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF 360
           ELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF
Sbjct: 301 ELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLF 360

Query: 361 RITSNAMINACRDFLELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLERAFHSA 420
           RITSNAMINACRDFLELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLERAFHSA
Sbjct: 361 RITSNAMINACRDFLELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLERAFHSA 420

Query: 421 PGRPANPSKSFIEGSLLTPKGEDSEEDEDTEYFDAMEDSTSFITVITEAKEDSRKAEGST 480
           PGRPANPSKSFIEGSLLTPKGEDSEEDEDTEYFDAMEDSTSFITVITEAKEDSRKAEGST
Sbjct: 421 PGRPANPSKSFIEGSLLTPKGEDSEEDEDTEYFDAMEDSTSFITVITEAKEDSRKAEGST 480

Query: 481 GTSSVDWSSADNVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPM 540
           GTSSVDWSSADNVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPM
Sbjct: 481 GTSSVDWSSADNVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPM 540

Query: 541 PVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFN 600
           PVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFN
Sbjct: 541 PVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFN 600

Query: 601 PMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISI 660
           PMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISI
Sbjct: 601 PMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISI 660

Query: 661 MPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPY 720
           MPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPY
Sbjct: 661 MPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPY 720

Query: 721 SYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTL 780
           SYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTL
Sbjct: 721 SYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTL 780

Query: 781 SAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTE 840
           SAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTE
Sbjct: 781 SAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTE 840

Query: 841 KQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGY 900
           KQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGY
Sbjct: 841 KQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGY 900

Query: 901 WEAKEKQDWHMCPNIF 916
           WEAKEKQDWHMCPNIF
Sbjct: 901 WEAKEKQDWHMCPNIF 916


>gi|4505531 oxysterol binding protein [Homo sapiens]
          Length = 807

 Score =  949 bits (2453), Expect = 0.0
 Identities = 496/827 (59%), Positives = 606/827 (73%), Gaps = 46/827 (5%)

Query: 93  GAGQPSELLQGSRPGSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPL 152
           GAG P     G R  +   SG  +G    AA      A G      P +G + A  P P 
Sbjct: 24  GAGPPVVGGGGGRGDAGPGSGAASGTVVAAA------AGGPG----PGAGGVAAAGPAPA 73

Query: 153 LRPGQAKTPLGVPMSGTGTTSSAPLALLPLDSFEGWLLKWTNYLKGYQRRWFVLGNGLLS 212
              G      G   SG G + SA          EGWL KWTNY+KGYQRRWFVL NGLLS
Sbjct: 74  PPTG------GSGGSGAGGSGSAR---------EGWLFKWTNYIKGYQRRWFVLSNGLLS 118

Query: 213 YYRNQGEMAHTCRGTINLSTAHIDTEDSCGILLTSG-ARSYHLKASSEVDRQQWITALEL 271
           YYR++ EM HTCRGTINL+TA+I  EDSC  ++++G A++YHLKASSEV+RQ+W+TALEL
Sbjct: 119 YYRSKAEMRHTCRGTINLATANITVEDSCNFIISNGGAQTYHLKASSEVERQRWVTALEL 178

Query: 272 AKAKAVRVMNTHSDDSGDDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQ 331
           AKAKAV+++   SD+SGD+ E+ +  DK+EL +TL+ LS K++DLSTCNDLIAKHG ALQ
Sbjct: 179 AKAKAVKML-AESDESGDE-ESVSQTDKTELQNTLRTLSSKVEDLSTCNDLIAKHGTALQ 236

Query: 332 RSLTELDGLKIPSESGEKLKVVNERATLFRITSNAMINACRDFLELAEIHSRKWQRALQY 391
           RSL+EL+ LK+P+ES EK+K VNERATLFRITSNAMINACRDFL LA+ HS+KWQ++LQY
Sbjct: 237 RSLSELESLKLPAESNEKIKQVNERATLFRITSNAMINACRDFLMLAQTHSKKWQKSLQY 296

Query: 392 EQEQRVHLEETIEQLAKQHNSLERAFHSAPGRPANPSKSFIEGS--LLTPKGEDSEEDED 449
           E++QR+ LEET+EQLAKQHN LERAF  A   PAN   +   G     + KG+ S+ED++
Sbjct: 297 ERDQRIRLEETLEQLAKQHNHLERAFRGATVLPANTPGNVGSGKDQCCSGKGDMSDEDDE 356

Query: 450 TEYFDAMEDSTSFITVITEAKEDSRKAEGSTGTSSVDWSSADNVLDGASLVPKGSSKVKR 509
            E+FDA E       +IT  +    K  GS    ++  +S+D  LD         +K ++
Sbjct: 357 NEFFDAPE-------IITMPENLGHKRTGS----NISGASSDISLDEQYKHQLEETKKEK 405

Query: 510 RVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVH 569
           R RIP KPNYSLNLWSIMKNCIG+ELS+IPMPVNFNEPLSMLQRLTEDLEYH LLD+A  
Sbjct: 406 RTRIPYKPNYSLNLWSIMKNCIGKELSKIPMPVNFNEPLSMLQRLTEDLEYHELLDRAAK 465

Query: 570 CTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLDDMGLRSLCEQVSHHPP 629
           C +S+EQ+C VAAF+VSSYSTTV R +KPFNP+LGETFELDRL++ G RSLCEQVSHHPP
Sbjct: 466 CENSLEQLCYVAAFTVSSYSTTVFRTSKPFNPLLGETFELDRLEENGYRSLCEQVSHHPP 525

Query: 630 SAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNI 689
           +AAH+  SK+GW+L QEI I+SKFRGKY+SIMPLG IH  F A+G+HY W+K T+TVHNI
Sbjct: 526 AAAHHAESKNGWTLRQEIKITSKFRGKYLSIMPLGTIHCIFHATGHHYTWKKVTTTVHNI 585

Query: 690 IVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGS 749
           IVGKLWIDQSG+I+IVNHKT D+C LKF+PYSYFS++ ARKVTG V+D  GK H+ L G+
Sbjct: 586 IVGKLWIDQSGEIDIVNHKTGDKCNLKFVPYSYFSRDVARKVTGEVTDPSGKVHFALLGT 645

Query: 750 WDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLN 809
           WDE+MEC KV      +   D +Q+      S  +LWK+ PLP+NAENMYYFSELALTLN
Sbjct: 646 WDEKMECFKVQPVIGEN-GGDARQRGHEAEESRVMLWKRNPLPKNAENMYYFSELALTLN 704

Query: 810 EHEEGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEE 869
             E G APTDSRLRPDQRLME GRWDEAN EKQRLEEKQRLSR++R EA    +  ++E+
Sbjct: 705 AWESGTAPTDSRLRPDQRLMENGRWDEANAEKQRLEEKQRLSRKKR-EA---EAMKATED 760

Query: 870 EKEADAYTPLWFEKRLDPLTGEMACVYKGGYWEAKEKQDWHMCPNIF 916
               D Y  LWFE++ DP+T E+  +Y+G YWE KEKQDW  CP+IF
Sbjct: 761 GTPYDPYKALWFERKKDPVTKELTHIYRGEYWECKEKQDWSSCPDIF 807


>gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo
           sapiens]
          Length = 950

 Score =  335 bits (859), Expect = 1e-91
 Identities = 252/766 (32%), Positives = 366/766 (47%), Gaps = 105/766 (13%)

Query: 182 LDSFEGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTC--RGTINLSTA--HIDT 237
           L  +EG L K + +  G++  W VL +G+LS+YR Q +  H    +G  +L+ A   + +
Sbjct: 235 LKRYEGPLWKSSRFF-GWRLFWVVLEHGVLSWYRKQPDAVHNIYRQGCKHLTQAVCTVKS 293

Query: 238 EDSCGILLTSGARSYH----LKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEA 293
            DSC   +     + H     K S +  R+ W+ A+E   A +    +       ++++ 
Sbjct: 294 TDSCLFFIKCFDDTIHGFRVPKNSLQQSREDWLEAIEEHSAYSTHYCSQDQLTDEEEEDT 353

Query: 294 TTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLK--IPSESGEKLK 351
            + AD          L   L+   +C   + +  +   + + E D  K  +PS   +K++
Sbjct: 354 VSAAD----------LKKSLEKAQSCQQRLDREISNFLKMIKECDMAKEMLPSFL-QKVE 402

Query: 352 VVNERATLFRITSNAMINACRDFLELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHN 411
           VV+E +   R T  A+ +    F +   + + K    L+ EQE+   L E +E LA +H+
Sbjct: 403 VVSEAS---RETCVALTDCLNLFTKQEGVRNFK----LEQEQEKNKILSEALETLATEHH 455

Query: 412 SLERAFHSAPGRPANPSKSFIEGSLLTPKGEDSEEDEDTEYFDAMEDSTS--FITVITEA 469
            LE+              S ++GS   P      EDE   ++DA+ DS S   ++ +   
Sbjct: 456 ELEQ--------------SLVKGS---PPASILSEDE---FYDALSDSESERSLSRLEAV 495

Query: 470 KEDSRKAEGSTGTSSVDWSSADNVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKN 529
              S + EG    S     S +    G   +  G  K +  +  P       ++WSI++ 
Sbjct: 496 TARSFEEEGEHLGSRKHRMSEEKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRK 555

Query: 530 CIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYS 589
           CIG ELS+I MPV FNEPLS LQRLTE +E+ +L+ KA   +  VE+M  VAAF+VS+ +
Sbjct: 556 CIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVA 615

Query: 590 TTVHRIAKPFNPMLGETFELDRLDDMGLRSLCEQVSHHPP-SAAHYVFSKHGWSLWQEIT 648
           +   R  KPFNP+LGET+EL R DD+G R + EQVSHHPP SA H     + +     I 
Sbjct: 616 SQWERTGKPFNPLLGETYELVR-DDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIY 674

Query: 649 ISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHK 708
              KF GK +   P G I LE       Y W   T  VHNIIVGKLWI+Q G++EI+NHK
Sbjct: 675 PKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHK 734

Query: 709 TNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDE---------------- 752
           T D+C L F P   F KE   KV G + D   K    L G W E                
Sbjct: 735 TGDKCVLNFKPCGLFGKE-LHKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKN 793

Query: 753 ------------QMECSKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYY 800
                       QM  S+ +   P   S     ++V+    + LLW+  P P N+  MY 
Sbjct: 794 DKKNTEEKKNSKQMSTSEELDEMPVPDS-----ESVFIIPGSVLLWRIAPRPPNSAQMYN 848

Query: 801 FSELALTLNEHE---EGVAP-TDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRL 856
           F+  A+ LNE +   E V P TD RLRPD R ME G  D+A+ EK+RLEEKQR +R+ R 
Sbjct: 849 FTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAARKNR- 907

Query: 857 EACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGYWE 902
                         K  + +   WF +  +P  G    +Y G YW+
Sbjct: 908 -------------SKSEEDWKTRWFHQGPNPYNGAQDWIYSGSYWD 940


>gi|21735584 oxysterol-binding protein-like protein 3 isoform d
           [Homo sapiens]
          Length = 820

 Score =  284 bits (726), Expect = 3e-76
 Identities = 224/753 (29%), Positives = 355/753 (47%), Gaps = 111/753 (14%)

Query: 186 EGWLLKWTNY-LKGYQRRWFVLGNGLLSYYRNQG----EMAHTCRGTINLSTAHIDTEDS 240
           +G+LLK   + LKG+ +R+F L  G+L Y ++Q     E  H C   + LS   +     
Sbjct: 55  KGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCID-VGLSVMSVKKSSK 113

Query: 241 CGILLTSGARSYHLKASSEVDRQQWITALE---LAKAKAVRVM----------NTHSDDS 287
           C I L +    YHLK  SE    +W++ L    + +   + +           +T +D S
Sbjct: 114 C-IDLDTEEHIYHLKVKSEEVFDEWVSKLRHHRMYRQNEIAMFPHEVNHFFSGSTITDSS 172

Query: 288 GD-----DDEATTPADKSELHHTLKNLSLKLD--------------------DLSTCNDL 322
                       +   K  L  T  N+S                        DL+ C+  
Sbjct: 173 SGVFDSISSRKRSSISKQNLFQTGSNVSFSCGGETRVPLWLQSSEDMEKCSKDLAHCHAY 232

Query: 323 IAKHGAALQR--------SLTELDGLKIPSESGEKLKVVNERATLFRI------------ 362
           + +    LQ         S   ++ +++P      +++ +    L  +            
Sbjct: 233 LVEMSQLLQSMDVLHRTYSAPAINAIQVPKPFSGPVRLHSSNPNLSTLDFGEEKNYSDGS 292

Query: 363 -TSNAMINACRDFLELAEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHNS-----LERA 416
            TS+       D   +A       + A      +R  L++ +EQ A    S     L+ A
Sbjct: 293 ETSSEFSKMQEDLCHIAHKVYFTLRSAFNIMSAEREKLKQLMEQDASSSPSAQVIGLKNA 352

Query: 417 FHSAPGRPANPSKSFIEGSLLTPKGEDSEEDEDTEYFDAMEDSTSFITVITEAKEDSRKA 476
             S   R  N  ++ +    L+ +   S  D  +E+FDA E   S  +   E  +D    
Sbjct: 353 LSSENSRDEN--RALVHQ--LSNESRLSITDSLSEFFDAQEVLLSPSSSENEISDDDSYV 408

Query: 477 EGSTGTSSVDWSSADNVLDGASLVPKGSS----KVKRRVRIPNK--PNYSLNLWSIMKNC 530
              +   S+D  S D   +  +L P   S    K +RR  +P     + +++LW+I++N 
Sbjct: 409 SDISDNLSLDNLSNDLDNERQTLGPVLDSGREAKSRRRTCLPAPCPSSSNISLWNILRNN 468

Query: 531 IGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYST 590
           IG++LS++ MPV  NEPL+ LQRL E+LEY  LLDKA    S +E+M  VAAF++S+Y++
Sbjct: 469 IGKDLSKVAMPVELNEPLNTLQRLCEELEYSELLDKAAQIPSPLERMVYVAAFAISAYAS 528

Query: 591 TVHRI-AKPFNPMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITI 649
           + +R  +KPFNP+LGET+E  R +D G +   EQVSHHPP +A +  S++ +  WQ++  
Sbjct: 529 SYYRAGSKPFNPVLGETYECIR-EDKGFQFFSEQVSHHPPISACHAESRN-FVFWQDVRW 586

Query: 650 SSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVN-HK 708
            +KF GK + I+P+G  H+     G+H+ W K TS +HNI+ G+ WI+  G+I I N H 
Sbjct: 587 KNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKVTSCIHNILSGQRWIEHYGEIVIKNLHD 646

Query: 709 TNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPS 768
            +  C++ F+   Y+S   A ++ G V D  GKA + L G W E + C            
Sbjct: 647 DSCYCKVNFIKAKYWSTN-AHEIEGTVFDRSGKAVHRLFGKWHESIYCG----------- 694

Query: 769 SDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEG----VAPTDSRLRP 824
                       S+  +W+  P+P+  E  Y F++ AL LNE +      + PTD+R RP
Sbjct: 695 ---------GGSSSACVWRANPMPKGYEQYYSFTQFALELNEMDPSSKSLLPPTDTRFRP 745

Query: 825 DQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLE 857
           DQR +E+G  +EA  +KQR+E+ QR  RRR LE
Sbjct: 746 DQRFLEEGNLEEAEIQKQRIEQLQR-ERRRVLE 777


>gi|19718746 oxysterol-binding protein-like 1A isoform A [Homo
           sapiens]
          Length = 437

 Score =  283 bits (724), Expect = 5e-76
 Identities = 176/431 (40%), Positives = 228/431 (52%), Gaps = 58/431 (13%)

Query: 508 KRRVRIPNKPNYSLN---LWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLL 564
           K R  +P+ P +S N   +WSI++ CIG ELS+I MPV FNEPLS LQRLTE +E+ +L+
Sbjct: 19  KHRTSLPS-PMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLI 77

Query: 565 DKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLDDMGLRSLCEQV 624
            KA   +  VE+M  VAAF+VS+ ++   R  KPFNP+LGET+EL R DD+G R + EQV
Sbjct: 78  HKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVR-DDLGFRLISEQV 136

Query: 625 SHHPP-SAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKST 683
           SHHPP SA H     + +     I    KF GK +   P G I LE       Y W   T
Sbjct: 137 SHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPT 196

Query: 684 STVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAH 743
             VHNIIVGKLWI+Q G++EI+NHKT D+C L F P   F KE   KV G + D   K  
Sbjct: 197 CCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKE-LHKVEGYIQDKSKKKL 255

Query: 744 YVLSGSWDE----------------------------QMECSKVMHSSPSSPSSDGKQKT 775
             L G W E                            QM  S+ +   P   S     ++
Sbjct: 256 CALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDS-----ES 310

Query: 776 VYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHE---EGVAP-TDSRLRPDQRLMEK 831
           V+    + LLW+  P P N+  MY F+  A+ LNE +   E V P TD RLRPD R ME 
Sbjct: 311 VFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMEN 370

Query: 832 GRWDEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGE 891
           G  D+A+ EK+RLEEKQR +R+ R               K  + +   WF +  +P  G 
Sbjct: 371 GEIDQASEEKKRLEEKQRAARKNR--------------SKSEEDWKTRWFHQGPNPYNGA 416

Query: 892 MACVYKGGYWE 902
              +Y G YW+
Sbjct: 417 QDWIYSGSYWD 427


>gi|7662298 oxysterol-binding protein-like protein 2 isoform 1 [Homo
           sapiens]
          Length = 468

 Score =  274 bits (701), Expect = 2e-73
 Identities = 178/499 (35%), Positives = 251/499 (50%), Gaps = 65/499 (13%)

Query: 449 DTEYFDAMEDSTSFITVITEAKEDSRKAEGSTGTSSVDWSSADNVLDGASLVPKGSSKVK 508
           + E+FDA+ ++   +T + +         G TG    +  S +N          G  K +
Sbjct: 4   EEEFFDAVTEANQKVTGMIDLDTSKNNRIGKTG----ERPSQEN----------GIQKHR 49

Query: 509 RRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAV 568
             +  P       ++W+I+K C+G ELS+I MP+ FNEPLS LQR+TE +E+ +L+ +A 
Sbjct: 50  TSLPAPMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIHRAS 109

Query: 569 HCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLDDMGLRSLCEQVSHHP 628
                +E+M  VAAF+VS+ ++   R  KPFNP+LGET+EL R +D+G R + EQVSHHP
Sbjct: 110 CQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIR-EDLGFRFISEQVSHHP 168

Query: 629 P-SAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVH 687
           P SA H     H +     I    KF GK +   P G I LE       Y W   T  VH
Sbjct: 169 PISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTCCVH 228

Query: 688 NIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLS 747
           N+I+GKLWI+Q G +EI+NH+T  +C L F P   F KE   KV G + D   K  +++ 
Sbjct: 229 NVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKE-LHKVEGHIQDKNKKKLFMIY 287

Query: 748 GSWDE---------------------QMECSKVMHSSPSSPSSDG-----KQKTVYQTLS 781
           G W E                      +  +K+   S  + S         Q+TV     
Sbjct: 288 GKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQVIPG 347

Query: 782 AKLLWKKYPLPENAENMYYFSELALTLNEHEEG----VAPTDSRLRPDQRLMEKGRWDEA 837
           +KLLW+    P N+  MY F+   ++LNE E G    + PTD RLRPD R ME G  D A
Sbjct: 348 SKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNMDLA 407

Query: 838 NTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYK 897
           + EK+RLEEKQR +RR              E  KE   +   WF    +P TG    +Y 
Sbjct: 408 SQEKERLEEKQREARR--------------ERAKEEAEWQTRWFYPGNNPYTGTPDWLYA 453

Query: 898 GGYWEAKEKQDWHMCPNIF 916
           G Y+E    +++  CP+I+
Sbjct: 454 GDYFE----RNFSDCPDIY 468


>gi|21450853 oxysterol-binding protein-like protein 2 isoform 2
           [Homo sapiens]
          Length = 480

 Score =  272 bits (695), Expect = 1e-72
 Identities = 181/502 (36%), Positives = 254/502 (50%), Gaps = 59/502 (11%)

Query: 449 DTEYFDAMEDSTSFITVITEAKEDSRKAEGSTGTSSVDWSSADNVLDGASLVPKGSSKVK 508
           + E+FDA+    S       + E S   +  TG   +D S  + +        + +   K
Sbjct: 4   EEEFFDAVTGFDSD----NSSGEFSEANQKVTGMIDLDTSKNNRIGKTGERPSQENGIQK 59

Query: 509 RRVRIPNKPNYS---LNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLD 565
            R  +P  P +S    ++W+I+K C+G ELS+I MP+ FNEPLS LQR+TE +E+ +L+ 
Sbjct: 60  HRTSLP-APMFSRSDFSVWTILKKCVGLELSKITMPIAFNEPLSFLQRITEYMEHVYLIH 118

Query: 566 KAVHCTSSVEQMCLVAAFSVSSYSTTVHRIAKPFNPMLGETFELDRLDDMGLRSLCEQVS 625
           +A      +E+M  VAAF+VS+ ++   R  KPFNP+LGET+EL R +D+G R + EQVS
Sbjct: 119 RASCQPQPLERMQSVAAFAVSAVASQWERTGKPFNPLLGETYELIR-EDLGFRFISEQVS 177

Query: 626 HHPP-SAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTS 684
           HHPP SA H     H +     I    KF GK +   P G I LE       Y W   T 
Sbjct: 178 HHPPISAFHSEGLNHDFLFHGSIYPKLKFWGKSVEAEPRGTITLELLKHNEAYTWTNPTC 237

Query: 685 TVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHY 744
            VHN+I+GKLWI+Q G +EI+NH+T  +C L F P   F KE   KV G + D   K  +
Sbjct: 238 CVHNVIIGKLWIEQYGTVEILNHRTGHKCVLHFKPCGLFGKE-LHKVEGHIQDKNKKKLF 296

Query: 745 VLSGSWDE---------------------QMECSKVMHSSPSSPSSDG-----KQKTVYQ 778
           ++ G W E                      +  +K+   S  + S         Q+TV  
Sbjct: 297 MIYGKWTECLWGIDPVSYESFKKQERRGDHLRKAKLDEDSGKADSDVADDVPVAQETVQV 356

Query: 779 TLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEG----VAPTDSRLRPDQRLMEKGRW 834
              +KLLW+    P N+  MY F+   ++LNE E G    + PTD RLRPD R ME G  
Sbjct: 357 IPGSKLLWRINTRPPNSAQMYNFTSFTVSLNELETGMEKTLPPTDCRLRPDIRGMENGNM 416

Query: 835 DEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMAC 894
           D A+ EK+RLEEKQR +RR              E  KE   +   WF    +P TG    
Sbjct: 417 DLASQEKERLEEKQREARR--------------ERAKEEAEWQTRWFYPGNNPYTGTPDW 462

Query: 895 VYKGGYWEAKEKQDWHMCPNIF 916
           +Y G Y+E    +++  CP+I+
Sbjct: 463 LYAGDYFE----RNFSDCPDIY 480


>gi|22035612 oxysterol-binding protein-like protein 6 isoform b
           [Homo sapiens]
          Length = 938

 Score =  271 bits (694), Expect = 2e-72
 Identities = 183/475 (38%), Positives = 268/475 (56%), Gaps = 53/475 (11%)

Query: 444 SEEDEDTEYFDAMEDSTSFITVITEAKED-SRKAEGSTGTSSVDWSSADNV----LDGAS 498
           S  +  +E+FDA E   S  +   EA +D S  ++ S   S  + S ADN+    L+G  
Sbjct: 491 SMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGE- 549

Query: 499 LVPKGSSKVKRRVRIPNK-PNYS-LNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTE 556
            +  G+ +  RR  +P   P+ S +NLW+I++N IG++LS++ MPV  NEPL+ LQ L E
Sbjct: 550 -LTGGAFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCE 608

Query: 557 DLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRI-AKPFNPMLGETFELDRLDDM 615
           ++EY  LLDKA       E+M LVAAF+VS Y +T  R  +KPFNP+LGET+E  R +D 
Sbjct: 609 EMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIR-EDK 667

Query: 616 GLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGN 675
           G R   EQVSHHPP +A +  SK+ +  WQ+I   +KF GK + I+P+G +++     G+
Sbjct: 668 GFRFFSEQVSHHPPISACHCESKN-FVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGD 726

Query: 676 HYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTN-DRCQLKFLPYSYFSKEAARKVTGV 734
           +YVW K T+ +HNI+ G+ WI+  G++ I N K++   C+L F+  +Y++     +V GV
Sbjct: 727 YYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSN-MNEVQGV 785

Query: 735 VSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPEN 794
           V D +GKA Y L G W E + C                        SAK +W+   +P N
Sbjct: 786 VIDQEGKAVYRLFGKWHEGLYCGVAP--------------------SAKCIWRPGSMPTN 825

Query: 795 AENMYYFSELALTLNEHE----EGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRL 850
            E  Y F+  A+ LNE +    + + PTD+R RPDQR +E+G  + A +EKQR+EE QR 
Sbjct: 826 YELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQR- 884

Query: 851 SRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGYWEAKE 905
           SRRR +E          E   E   + P +F+K +D    E A V    YWE ++
Sbjct: 885 SRRRYME----------ENNLE---HIPKFFKKVIDANQRE-AWVSNDTYWELRK 925



 Score = 38.9 bits (89), Expect = 0.022
 Identities = 27/90 (30%), Positives = 47/90 (52%), Gaps = 3/90 (3%)

Query: 183 DSFEGWLLKWTNY-LKGYQRRWFVLGNGLLSYYRNQGEMAH-TCRGTINLSTAHIDTEDS 240
           D  EG++LK   + LKG+ +R+FVL NG+L Y +   ++      G+I++  + +  +  
Sbjct: 66  DKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKK 125

Query: 241 C-GILLTSGARSYHLKASSEVDRQQWITAL 269
              I L +    YHLK  S+     W++ L
Sbjct: 126 ARRIDLDTEEHIYHLKVKSQDWFDAWVSKL 155


>gi|14210532 oxysterol-binding protein-like protein 6 isoform a
           [Homo sapiens]
          Length = 934

 Score =  271 bits (694), Expect = 2e-72
 Identities = 183/475 (38%), Positives = 268/475 (56%), Gaps = 53/475 (11%)

Query: 444 SEEDEDTEYFDAMEDSTSFITVITEAKED-SRKAEGSTGTSSVDWSSADNV----LDGAS 498
           S  +  +E+FDA E   S  +   EA +D S  ++ S   S  + S ADN+    L+G  
Sbjct: 487 SMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGE- 545

Query: 499 LVPKGSSKVKRRVRIPNK-PNYS-LNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTE 556
            +  G+ +  RR  +P   P+ S +NLW+I++N IG++LS++ MPV  NEPL+ LQ L E
Sbjct: 546 -LTGGAFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCE 604

Query: 557 DLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRI-AKPFNPMLGETFELDRLDDM 615
           ++EY  LLDKA       E+M LVAAF+VS Y +T  R  +KPFNP+LGET+E  R +D 
Sbjct: 605 EMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIR-EDK 663

Query: 616 GLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGN 675
           G R   EQVSHHPP +A +  SK+ +  WQ+I   +KF GK + I+P+G +++     G+
Sbjct: 664 GFRFFSEQVSHHPPISACHCESKN-FVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGD 722

Query: 676 HYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTN-DRCQLKFLPYSYFSKEAARKVTGV 734
           +YVW K T+ +HNI+ G+ WI+  G++ I N K++   C+L F+  +Y++     +V GV
Sbjct: 723 YYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSN-MNEVQGV 781

Query: 735 VSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPEN 794
           V D +GKA Y L G W E + C                        SAK +W+   +P N
Sbjct: 782 VIDQEGKAVYRLFGKWHEGLYCGVAP--------------------SAKCIWRPGSMPTN 821

Query: 795 AENMYYFSELALTLNEHE----EGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRL 850
            E  Y F+  A+ LNE +    + + PTD+R RPDQR +E+G  + A +EKQR+EE QR 
Sbjct: 822 YELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQR- 880

Query: 851 SRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKRLDPLTGEMACVYKGGYWEAKE 905
           SRRR +E          E   E   + P +F+K +D    E A V    YWE ++
Sbjct: 881 SRRRYME----------ENNLE---HIPKFFKKVIDANQRE-AWVSNDTYWELRK 921



 Score = 38.9 bits (89), Expect = 0.022
 Identities = 27/90 (30%), Positives = 47/90 (52%), Gaps = 3/90 (3%)

Query: 183 DSFEGWLLKWTNY-LKGYQRRWFVLGNGLLSYYRNQGEMAH-TCRGTINLSTAHIDTEDS 240
           D  EG++LK   + LKG+ +R+FVL NG+L Y +   ++      G+I++  + +  +  
Sbjct: 87  DKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKK 146

Query: 241 C-GILLTSGARSYHLKASSEVDRQQWITAL 269
              I L +    YHLK  S+     W++ L
Sbjct: 147 ARRIDLDTEEHIYHLKVKSQDWFDAWVSKL 176


>gi|21735582 oxysterol-binding protein-like protein 3 isoform c
           [Homo sapiens]
          Length = 851

 Score =  266 bits (681), Expect = 5e-71
 Identities = 173/480 (36%), Positives = 264/480 (55%), Gaps = 45/480 (9%)

Query: 395 QRVHLEETIEQLAKQHNS-----LERAFHSAPGRPANPSKSFIEGSLLTPKGEDSEEDED 449
           +R  L++ +EQ A    S     L+ A  S   R  N  ++ +    L+ +   S  D  
Sbjct: 357 EREKLKQLMEQDASSSPSAQVIGLKNALSSENSRDEN--RALVHQ--LSNESRLSITDSL 412

Query: 450 TEYFDAMEDSTSFITVITEAKEDSRKAEGSTGTSSVDWSSADNVLDGASLVPKGSS---- 505
           +E+FDA E   S  +   E  +D       +   S+D  S D   +  +L P   S    
Sbjct: 413 SEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSGREA 472

Query: 506 KVKRRVRIPNK--PNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHL 563
           K +RR  +P     + +++LW+I++N IG++LS++ MPV  NEPL+ LQRL E+LEY  L
Sbjct: 473 KSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEYSEL 532

Query: 564 LDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRI-AKPFNPMLGETFELDRLDDMGLRSLCE 622
           LDKA    S +E+M  VAAF++S+Y+++ +R  +KPFNP+LGET+E  R +D G +   E
Sbjct: 533 LDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIR-EDKGFQFFSE 591

Query: 623 QVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKS 682
           QVSHHPP +A +  S++ +  WQ++   +KF GK + I+P+G  H+     G+H+ W K 
Sbjct: 592 QVSHHPPISACHAESRN-FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEWNKV 650

Query: 683 TSTVHNIIVGKLWIDQSGDIEIVN-HKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGK 741
           TS +HNI+ G+ WI+  G+I I N H  +  C++ F+   Y+S   A ++ G V D  GK
Sbjct: 651 TSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTN-AHEIEGTVFDRSGK 709

Query: 742 AHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYYF 801
           A + L G W E + C                        S+  +W+  P+P+  E  Y F
Sbjct: 710 AVHRLFGKWHESIYCG--------------------GGSSSACVWRANPMPKGYEQYYSF 749

Query: 802 SELALTLNEHEEG----VAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLE 857
           ++ AL LNE +      + PTD+R RPDQR +E+G  +EA  +KQR+E+ QR  RRR LE
Sbjct: 750 TQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQR-ERRRVLE 808



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 7/89 (7%)

Query: 186 EGWLLKWTNY-LKGYQRRWFVLGNGLLSYYRNQ----GEMAHTCRGTINLSTAHIDTEDS 240
           +G+LLK   + LKG+ +R+F L  G+L Y ++Q     E  H C   + LS   +     
Sbjct: 55  KGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCI-DVGLSVMSVKKSSK 113

Query: 241 CGILLTSGARSYHLKASSEVDRQQWITAL 269
           C I L +    YHLK  SE    +W++ L
Sbjct: 114 C-IDLDTEEHIYHLKVKSEEVFDEWVSKL 141


>gi|21735580 oxysterol-binding protein-like protein 3 isoform b
           [Homo sapiens]
          Length = 856

 Score =  266 bits (679), Expect = 9e-71
 Identities = 160/423 (37%), Positives = 241/423 (56%), Gaps = 36/423 (8%)

Query: 447 DEDTEYFDAMEDSTSFITVITEAKEDSRKAEGSTGTSSVDWSSADNVLDGASLVPKGSS- 505
           D  +E+FDA E   S  +   E  +D       +   S+D  S D   +  +L P   S 
Sbjct: 415 DSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSG 474

Query: 506 ---KVKRRVRIPNK--PNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEY 560
              K +RR  +P     + +++LW+I++N IG++LS++ MPV  NEPL+ LQRL E+LEY
Sbjct: 475 REAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEY 534

Query: 561 HHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRI-AKPFNPMLGETFELDRLDDMGLRS 619
             LLDKA    S +E+M  VAAF++S+Y+++ +R  +KPFNP+LGET+E  R +D G + 
Sbjct: 535 SELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIR-EDKGFQF 593

Query: 620 LCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVW 679
             EQVSHHPP +A +  S++ +  WQ++   +KF GK + I+P+G  H+     G+H+ W
Sbjct: 594 FSEQVSHHPPISACHAESRN-FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEW 652

Query: 680 RKSTSTVHNIIVGKLWIDQSGDIEIVN-HKTNDRCQLKFLPYSYFSKEAARKVTGVVSDS 738
            K TS +HNI+ G+ WI+  G+I I N H  +  C++ F+   Y+S   A ++ G V D 
Sbjct: 653 NKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTN-AHEIEGTVFDR 711

Query: 739 QGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENM 798
            GKA + L G W E + C                        S+  +W+  P+P+  E  
Sbjct: 712 SGKAVHRLFGKWHESIYCG--------------------GGSSSACVWRANPMPKGYEQY 751

Query: 799 YYFSELALTLNEHEEG----VAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRR 854
           Y F++ AL LNE +      + PTD+R RPDQR +E+G  +EA  +KQR+E+ QR  RRR
Sbjct: 752 YSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQR-ERRR 810

Query: 855 RLE 857
            LE
Sbjct: 811 VLE 813



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 7/89 (7%)

Query: 186 EGWLLKWTNY-LKGYQRRWFVLGNGLLSYYRNQ----GEMAHTCRGTINLSTAHIDTEDS 240
           +G+LLK   + LKG+ +R+F L  G+L Y ++Q     E  H C   + LS   +     
Sbjct: 55  KGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCI-DVGLSVMSVKKSSK 113

Query: 241 CGILLTSGARSYHLKASSEVDRQQWITAL 269
           C I L +    YHLK  SE    +W++ L
Sbjct: 114 C-IDLDTEEHIYHLKVKSEEVFDEWVSKL 141


>gi|14149704 oxysterol-binding protein-like protein 3 isoform a
           [Homo sapiens]
          Length = 887

 Score =  266 bits (679), Expect = 9e-71
 Identities = 160/423 (37%), Positives = 241/423 (56%), Gaps = 36/423 (8%)

Query: 447 DEDTEYFDAMEDSTSFITVITEAKEDSRKAEGSTGTSSVDWSSADNVLDGASLVPKGSS- 505
           D  +E+FDA E   S  +   E  +D       +   S+D  S D   +  +L P   S 
Sbjct: 446 DSLSEFFDAQEVLLSPSSSENEISDDDSYVSDISDNLSLDNLSNDLDNERQTLGPVLDSG 505

Query: 506 ---KVKRRVRIPNK--PNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEY 560
              K +RR  +P     + +++LW+I++N IG++LS++ MPV  NEPL+ LQRL E+LEY
Sbjct: 506 REAKSRRRTCLPAPCPSSSNISLWNILRNNIGKDLSKVAMPVELNEPLNTLQRLCEELEY 565

Query: 561 HHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRI-AKPFNPMLGETFELDRLDDMGLRS 619
             LLDKA    S +E+M  VAAF++S+Y+++ +R  +KPFNP+LGET+E  R +D G + 
Sbjct: 566 SELLDKAAQIPSPLERMVYVAAFAISAYASSYYRAGSKPFNPVLGETYECIR-EDKGFQF 624

Query: 620 LCEQVSHHPPSAAHYVFSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVW 679
             EQVSHHPP +A +  S++ +  WQ++   +KF GK + I+P+G  H+     G+H+ W
Sbjct: 625 FSEQVSHHPPISACHAESRN-FVFWQDVRWKNKFWGKSMEIVPIGTTHVTLPVFGDHFEW 683

Query: 680 RKSTSTVHNIIVGKLWIDQSGDIEIVN-HKTNDRCQLKFLPYSYFSKEAARKVTGVVSDS 738
            K TS +HNI+ G+ WI+  G+I I N H  +  C++ F+   Y+S   A ++ G V D 
Sbjct: 684 NKVTSCIHNILSGQRWIEHYGEIVIKNLHDDSCYCKVNFIKAKYWSTN-AHEIEGTVFDR 742

Query: 739 QGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENM 798
            GKA + L G W E + C                        S+  +W+  P+P+  E  
Sbjct: 743 SGKAVHRLFGKWHESIYCG--------------------GGSSSACVWRANPMPKGYEQY 782

Query: 799 YYFSELALTLNEHEEG----VAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRR 854
           Y F++ AL LNE +      + PTD+R RPDQR +E+G  +EA  +KQR+E+ QR  RRR
Sbjct: 783 YSFTQFALELNEMDPSSKSLLPPTDTRFRPDQRFLEEGNLEEAEIQKQRIEQLQR-ERRR 841

Query: 855 RLE 857
            LE
Sbjct: 842 VLE 844



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 7/89 (7%)

Query: 186 EGWLLKWTNY-LKGYQRRWFVLGNGLLSYYRNQ----GEMAHTCRGTINLSTAHIDTEDS 240
           +G+LLK   + LKG+ +R+F L  G+L Y ++Q     E  H C   + LS   +     
Sbjct: 55  KGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCI-DVGLSVMSVKKSSK 113

Query: 241 CGILLTSGARSYHLKASSEVDRQQWITAL 269
           C I L +    YHLK  SE    +W++ L
Sbjct: 114 C-IDLDTEEHIYHLKVKSEEVFDEWVSKL 141


>gi|22035616 oxysterol-binding protein-like protein 7 [Homo sapiens]
          Length = 842

 Score =  253 bits (646), Expect = 6e-67
 Identities = 156/454 (34%), Positives = 246/454 (54%), Gaps = 49/454 (10%)

Query: 424 PANPSKSFIEGSLLTPKGEDSE----EDEDTEYFDAMEDSTSFITVITEAKEDSRKAEGS 479
           P      +++G  LTP+   +      D  TE+FDA E     + +   + E+    E  
Sbjct: 371 PEEQEALYMKGRELTPQLSQTSILSLADSHTEFFDACE-----VLLSASSSENEGSEEEE 425

Query: 480 TGTSSVDWSSADNVLD--GASLVPKGSSKVKRRVRIPNK--------PNYSLNLWSIMKN 529
           + TS +  S ++ +LD  GA    KG     R +  P +        P   ++LW+I++N
Sbjct: 426 SCTSEITTSLSEEMLDLRGAERCQKGGCVPGRPMGPPRRRCLPAASGPGADVSLWNILRN 485

Query: 530 CIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYS 589
            IG++LS++ MPV  NEPL+ LQRL E+LEY  LLD+A       E+M  +AAF+VS+YS
Sbjct: 486 NIGKDLSKVSMPVQLNEPLNTLQRLCEELEYSSLLDQASRIADPCERMVYIAAFAVSAYS 545

Query: 590 TTVHRI-AKPFNPMLGETFELDRLDDMGLRSLCEQVSHHPPSAAHYVFSKHGWSLWQEIT 648
           +T HR   KPFNP+LGET+E +R  D G R + EQVSHHPP +A +  S++ ++ WQ++ 
Sbjct: 546 STYHRAGCKPFNPVLGETYECER-PDRGFRFISEQVSHHPPISACHAESEN-FAFWQDMK 603

Query: 649 ISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHK 708
             +KF GK + I+P+G +++     G+H+ W K TS +HN++ G+ WI+  G++ I N +
Sbjct: 604 WKNKFWGKSLEIVPVGTVNVSLPRFGDHFEWNKVTSCIHNVLSGQRWIEHYGEVLIRNTQ 663

Query: 709 TND-RCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSP 767
            +   C++ F    Y+S     +V G V    G+  + L G W E       ++  P   
Sbjct: 664 DSSCHCKITFCKAKYWSSN-VHEVQGAVLSRSGRVLHRLFGKWHEG------LYRGP--- 713

Query: 768 SSDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLN----EHEEGVAPTDSRLR 823
                      T   + +WK   +P + E  + F++ AL LN    E +  +  TD+RLR
Sbjct: 714 -----------TPGGQCIWKPNSMPPDHERNFGFTQFALELNELTAELKRSLPSTDTRLR 762

Query: 824 PDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLE 857
           PDQR +E+G    A  +K+R+E+ QR  RR+ +E
Sbjct: 763 PDQRYLEEGNIQAAEAQKRRIEQLQR-DRRKVME 795



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 3/87 (3%)

Query: 186 EGWLLKWTNY-LKGYQRRWFVLGNGLLSYYRNQGEMAH-TCRGTINLSTAHID-TEDSCG 242
           EG LLK   + LKG+ +R+FVL +G+L Y   + ++      G+I++  + +   + +  
Sbjct: 51  EGHLLKKRKWPLKGWHKRYFVLEDGILHYATTRQDITKGKLHGSIDVRLSVMSINKKAQR 110

Query: 243 ILLTSGARSYHLKASSEVDRQQWITAL 269
           I L +    YHLK  S+   Q W+  L
Sbjct: 111 IDLDTEDNIYHLKIKSQDLFQSWVAQL 137


>gi|22547173 oxysterol binding protein-like 9 isoform d [Homo
           sapiens]
          Length = 723

 Score =  104 bits (260), Expect = 3e-22
 Identities = 175/757 (23%), Positives = 282/757 (37%), Gaps = 156/757 (20%)

Query: 186 EGWLLKWTNYLKGYQRRWFVL--GNGLLSYYRNQGEMAH-TCRGTINLSTA--HIDTEDS 240
           EG L KWTN +KG+Q RWFVL    GLLSYY ++ +M   + RG + L  A   ID ED 
Sbjct: 6   EGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDD 65

Query: 241 CGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSG------DDDEAT 294
               +T   +++H +A    +R++WI ALE    +    +     DSG      D D+  
Sbjct: 66  STFTITVDQKTFHFQARDADEREKWIHALEETILR--HTLQLQGLDSGFVPSVQDFDKKL 123

Query: 295 TPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVN 354
           T AD + L   ++ L L  D L  C +                       E  +K++ + 
Sbjct: 124 TEAD-AYLQILIEQLKLFDDKLQNCKE----------------------DEQRKKIETLK 160

Query: 355 ERATLFRITSNAMINA---CRDFLELAE------------------IHSRKWQRALQYEQ 393
           E       T+N+M+ +   C   L++A+                  I +   Q  L  E 
Sbjct: 161 E-------TTNSMVESIKHCIVLLQIAKSTINPVDAIYQPSPLEPVISTMPSQTVLPPEP 213

Query: 394 EQRVHLEETIEQLAKQHNSLERAFHSAPGRPANPSKSFIEGSLLTPKG----------ED 443
            Q    E+    L           H  P   +  S      S LT             E 
Sbjct: 214 VQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEF 273

Query: 444 SEEDEDTEYFDAME------------DSTSFITVITEAKEDSRKAEGSTGTSSVDWSSAD 491
           S    + E++DA E            DS+   +V+T +   +      T T S++ SS  
Sbjct: 274 SYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDT-TESLN-SSLS 331

Query: 492 NVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSML 551
           N    A L      +         + + S+ +  + +  +G +L+++ +P    E  S+L
Sbjct: 332 NGTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLL 391

Query: 552 QRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSY--STTVHRIAKPFNPMLGETFEL 609
           +   +   +  L           ++M  V  + +S++          KP+NP+LGE F+ 
Sbjct: 392 EMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQC 451

Query: 610 ------DRLDDMGLRS--------------LCEQVSHHPPSAAHYV--------FSKHGW 641
                 D  ++  L S              + EQVSHHPP +A Y         F+ H W
Sbjct: 452 HWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIW 511

Query: 642 SLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGD 701
           +        SKF G  I +  +G   +       HY+         +I+    W++  G+
Sbjct: 512 T-------KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVP-WVELGGE 563

Query: 702 IEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMH 761
             I   KT     + F    ++  +  R    + S +  K+   + G W      + VM+
Sbjct: 564 CNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEW------NGVMY 617

Query: 762 SSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSR 821
           +  ++    G+      T    ++ KK    E+              NE+E         
Sbjct: 618 AKYAT----GENTVFVDTKKLPIIKKKVRKLEDQ-------------NEYE------SRS 654

Query: 822 LRPDQRLMEKGRWDEANTE-KQRLEEKQRLSRRRRLE 857
           L  D     K R  +A TE K RLEE+QR   R R E
Sbjct: 655 LWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKE 691


>gi|14149740 oxysterol-binding protein-like protein 5 isoform a
           [Homo sapiens]
          Length = 879

 Score =  103 bits (257), Expect = 7e-22
 Identities = 107/409 (26%), Positives = 172/409 (42%), Gaps = 46/409 (11%)

Query: 467 TEAKEDSRKAEGSTGTSSVDWSSADNVLDGASLVPK-----GSSKVKRRVRIPNKPNYSL 521
           TE ++ SRK E  +  S    +    V  G + V +     G      +V   ++ N SL
Sbjct: 314 TETQDHSRKTESGSDQSETPGAP---VRRGTTYVEQVQEELGELGEASQVETVSEENKSL 370

Query: 522 NLWSIMKNCI-GRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLV 580
            +W+++K    G +LSR+ +P    EP S L +L++   +  LL +A     +  +M LV
Sbjct: 371 -MWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLV 429

Query: 581 AAFSVSSYSTTVHRIAKPFNPMLGETFE---LDRLDDMGLRSLCEQVSHHPP-SAAHYVF 636
             + +S +      I KP+NP+LGETF         D     + EQVSHHPP SA H   
Sbjct: 430 LRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVSN 489

Query: 637 SKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWI 696
            K G+ +   IT  S+F G  +S +  G   L F      Y      +    I+ G + +
Sbjct: 490 RKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMTL 549

Query: 697 DQSGDIEIVNHKTNDRCQLKFLPYSYF-SKEAARKVTGVVSDSQGKAHYVLSGSWDEQME 755
           +  G + I   K N + QL+F    +F    +  +++G ++  + +    LSG WD  + 
Sbjct: 550 ELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGE-EVLASLSGHWDRDVF 608

Query: 756 CSKVMHSSPS---SPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHE 812
             +    S +   +PS + +++ + Q           PL E  E                
Sbjct: 609 IKEEGSGSSALFWTPSGEVRRQRLRQ--------HTVPLEEQTE---------------- 644

Query: 813 EGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLEACGP 861
                ++   +   R + KG    A  EK  LEE QR   R R E+  P
Sbjct: 645 ---LESERLWQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMP 690


>gi|221136766 oxysterol-binding protein-like protein 5 isoform b
           [Homo sapiens]
          Length = 811

 Score =  103 bits (257), Expect = 7e-22
 Identities = 107/409 (26%), Positives = 172/409 (42%), Gaps = 46/409 (11%)

Query: 467 TEAKEDSRKAEGSTGTSSVDWSSADNVLDGASLVPK-----GSSKVKRRVRIPNKPNYSL 521
           TE ++ SRK E  +  S    +    V  G + V +     G      +V   ++ N SL
Sbjct: 246 TETQDHSRKTESGSDQSETPGAP---VRRGTTYVEQVQEELGELGEASQVETVSEENKSL 302

Query: 522 NLWSIMKNCI-GRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLV 580
            +W+++K    G +LSR+ +P    EP S L +L++   +  LL +A     +  +M LV
Sbjct: 303 -MWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLV 361

Query: 581 AAFSVSSYSTTVHRIAKPFNPMLGETFE---LDRLDDMGLRSLCEQVSHHPP-SAAHYVF 636
             + +S +      I KP+NP+LGETF         D     + EQVSHHPP SA H   
Sbjct: 362 LRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVSN 421

Query: 637 SKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWI 696
            K G+ +   IT  S+F G  +S +  G   L F      Y      +    I+ G + +
Sbjct: 422 RKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMTL 481

Query: 697 DQSGDIEIVNHKTNDRCQLKFLPYSYF-SKEAARKVTGVVSDSQGKAHYVLSGSWDEQME 755
           +  G + I   K N + QL+F    +F    +  +++G ++  + +    LSG WD  + 
Sbjct: 482 ELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGE-EVLASLSGHWDRDVF 540

Query: 756 CSKVMHSSPS---SPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHE 812
             +    S +   +PS + +++ + Q           PL E  E                
Sbjct: 541 IKEEGSGSSALFWTPSGEVRRQRLRQ--------HTVPLEEQTE---------------- 576

Query: 813 EGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLEACGP 861
                ++   +   R + KG    A  EK  LEE QR   R R E+  P
Sbjct: 577 ---LESERLWQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMP 622


>gi|22035609 oxysterol-binding protein-like protein 5 isoform b
           [Homo sapiens]
          Length = 811

 Score =  103 bits (257), Expect = 7e-22
 Identities = 107/409 (26%), Positives = 172/409 (42%), Gaps = 46/409 (11%)

Query: 467 TEAKEDSRKAEGSTGTSSVDWSSADNVLDGASLVPK-----GSSKVKRRVRIPNKPNYSL 521
           TE ++ SRK E  +  S    +    V  G + V +     G      +V   ++ N SL
Sbjct: 246 TETQDHSRKTESGSDQSETPGAP---VRRGTTYVEQVQEELGELGEASQVETVSEENKSL 302

Query: 522 NLWSIMKNCI-GRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLV 580
            +W+++K    G +LSR+ +P    EP S L +L++   +  LL +A     +  +M LV
Sbjct: 303 -MWTLLKQLRPGMDLSRVVLPTFVLEPRSFLNKLSDYYYHADLLSRAAVEEDAYSRMKLV 361

Query: 581 AAFSVSSYSTTVHRIAKPFNPMLGETFE---LDRLDDMGLRSLCEQVSHHPP-SAAHYVF 636
             + +S +      I KP+NP+LGETF         D     + EQVSHHPP SA H   
Sbjct: 362 LRWYLSGFYKKPKGIKKPYNPILGETFRCCWFHPQTDSRTFYIAEQVSHHPPVSAFHVSN 421

Query: 637 SKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWI 696
            K G+ +   IT  S+F G  +S +  G   L F      Y      +    I+ G + +
Sbjct: 422 RKDGFCISGSITAKSRFYGNSLSALLDGKATLTFLNRAEDYTLTMPYAHCKGILYGTMTL 481

Query: 697 DQSGDIEIVNHKTNDRCQLKFLPYSYF-SKEAARKVTGVVSDSQGKAHYVLSGSWDEQME 755
           +  G + I   K N + QL+F    +F    +  +++G ++  + +    LSG WD  + 
Sbjct: 482 ELGGKVTIECAKNNFQAQLEFKLKPFFGGSTSINQISGKITSGE-EVLASLSGHWDRDVF 540

Query: 756 CSKVMHSSPS---SPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHE 812
             +    S +   +PS + +++ + Q           PL E  E                
Sbjct: 541 IKEEGSGSSALFWTPSGEVRRQRLRQ--------HTVPLEEQTE---------------- 576

Query: 813 EGVAPTDSRLRPDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLEACGP 861
                ++   +   R + KG    A  EK  LEE QR   R R E+  P
Sbjct: 577 ---LESERLWQHVTRAISKGDQHRATQEKFALEEAQRQRARERQESLMP 622


>gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]
          Length = 747

 Score =  102 bits (255), Expect = 1e-21
 Identities = 158/767 (20%), Positives = 279/767 (36%), Gaps = 155/767 (20%)

Query: 182 LDSFEGWLLKWTNYLKGYQRRWFVLGN--GLLSYYRNQGEMAHTCRGTINLSTAHIDTED 239
           +++  G+L+K+TN + G+Q R+FVL N  GLL Y+ N+       RGT+ L+ A I   D
Sbjct: 58  MENVYGYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSD 117

Query: 240 SCGILLTSGARS---YHLKASSEVDRQQWITALELAKAKAVRVMNTH-----------SD 285
                 T  A S   Y L+A+   +RQ W++ L++        +  +           + 
Sbjct: 118 EDSHTFTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLAS 177

Query: 286 DSGDDDEATTPADK---------SELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTE 336
            S        P+           S+L    K  +L  D L    ++++ H    QR L  
Sbjct: 178 SSNSPISQRRPSQNAISFFNVGHSKLQSLSKRTNLPPDHLVEVREMMS-HAEGQQRDL-- 234

Query: 337 LDGLKIPSESGEKLKVVNERATLFRITSNAMINACRDFLELAEIHSRKWQRALQYEQEQR 396
           +  ++    SG  L  +++   + + TS A +N   D   + ++     Q+         
Sbjct: 235 IRRIECLPTSGH-LSSLDQDLLMLKATSMATMNCLNDCFHILQLQHASHQKGSLPSGTTI 293

Query: 397 VHLEETIEQLAKQHNSLERAFHSAPGRPANPSKSFIEGSLLTPKGEDSEEDEDTEYFDAM 456
             LE  I       N  ++ F +   +P     +  E   +   G  + E E+    D +
Sbjct: 294 EWLEPKISLSNHYKNGADQPFATDQSKPV----AVPEEQPVAESGLLAREPEEINADDEI 349

Query: 457 EDSTSFITVITEAKEDSRKAEGSTGTSSVDWSSADNVLDGASLVPKGSSKVKRRVRIPNK 516
           ED+        + KED   A                                    +  +
Sbjct: 350 EDT-------CDHKEDDLGA------------------------------------VEEQ 366

Query: 517 PNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQ 576
            +  L+L S +K  +G +L+R+ +P    E  S+L+   + + +  L     +  ++ ++
Sbjct: 367 RSVILHLLSQLK--LGMDLTRVVLPTFILEKRSLLEMYADFMSHPDLFIAITNGATAEDR 424

Query: 577 MCLVAAFSVSSYSTTVHR------IAKPFNPMLGETFEL--------------------- 609
           M       V  Y T+ H         KP+NP++GETF                       
Sbjct: 425 MIRF----VEYYLTSFHEGRKGAIAKKPYNPIIGETFHCSWKMPKSEVASSVFSSSSTQG 480

Query: 610 ---------DRLDDMG-----LRSLCEQVSHHPPSAAHYV-FSKHGWSLWQEITISSKFR 654
                    + L  +G     +R + EQVSHHPP +  Y   ++    +   +   SKF 
Sbjct: 481 VTNHAPLSGESLTQVGSDCYTVRFVAEQVSHHPPVSGFYAECTERKMCVNAHVWTKSKFL 540

Query: 655 GKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQ 714
           G  I +  +G   L     G  Y +    +   +I+    W++  G + +   KT     
Sbjct: 541 GMSIGVTMVGEGILSLLEHGEEYTFSLPCAYARSILTVP-WVELGGKVSVNCAKTGYSAS 599

Query: 715 LKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQK 774
           + F    ++  +  R    V  +        + G W+  +E +           S+G+ K
Sbjct: 600 ITFHTKPFYGGKLHRVTAEVKHNITNTVVCRVQGEWNSVLEFT----------YSNGETK 649

Query: 775 TVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRW 834
             Y  L+   + KK   P   ++ +    L   +         TDS        + +   
Sbjct: 650 --YVDLTKLAVTKKRVRPLEKQDPFESRRLWKNV---------TDS--------LRESEI 690

Query: 835 DEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAY-TPLW 880
           D+A   K  LEE+QR   R R E   P  +    +E +   Y  PLW
Sbjct: 691 DKATEHKHTLEERQRTEERHRTETGTPWKTKYFIKEGDGWVYHKPLW 737


>gi|20070331 oxysterol binding protein-like 9 isoform e [Homo
           sapiens]
          Length = 736

 Score =  102 bits (253), Expect = 2e-21
 Identities = 176/750 (23%), Positives = 282/750 (37%), Gaps = 129/750 (17%)

Query: 186 EGWLLKWTNYLKGYQRRWFVL--GNGLLSYYRNQGEMAH-TCRGTINLSTA--HIDTEDS 240
           EG L KWTN +KG+Q RWFVL    GLLSYY ++ +M   + RG + L  A   ID ED 
Sbjct: 6   EGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDD 65

Query: 241 CGILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSG------DDDEAT 294
               +T   +++H +A    +R++WI ALE    +    +     DSG      D D+  
Sbjct: 66  STFTITVDQKTFHFQARDADEREKWIHALEETILR--HTLQLQGLDSGFVPSVQDFDKKL 123

Query: 295 TPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSES-GEKLKVV 353
           T AD + L   ++ L L  D L  C +              +++ LK  + S  E +K  
Sbjct: 124 TEAD-AYLQILIEQLKLFDDKLQNCKE---------DEQRKKIETLKETTNSMVESIKHC 173

Query: 354 NERATLFRITSNA------MINACRDFLELAE-------IHSRKWQRALQYEQEQRVHLE 400
                + +  SNA      MI+       + +       I +   Q  L  E  Q    E
Sbjct: 174 IVLLQIAKDQSNAEKHADGMISTINPVDAIYQPSPLEPVISTMPSQTVLPPEPVQLCKSE 233

Query: 401 ETIEQLAKQHNSLERAFHSAPGRPANPSKSFIEGSLLTPKG----------EDSEEDEDT 450
           +    L           H  P   +  S      S LT             E S    + 
Sbjct: 234 QRPSSLPVGPVLATLGHHQTPTPNSTGSGHSPPSSSLTSPSHVNLSPNTVPEFSYSSSED 293

Query: 451 EYFDAME------------DSTSFITVITEAKEDSRKAEGSTGTSSVDWSSADNVLDGAS 498
           E++DA E            DS+   +V+T +   +      T T S++ SS  N    A 
Sbjct: 294 EFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDT-TESLN-SSLSNGTSDAD 351

Query: 499 LVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDL 558
           L      +         + + S+ +  + +  +G +L+++ +P    E  S+L+   +  
Sbjct: 352 LFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRSLLEMYADFF 411

Query: 559 EYHHLLDKAVHCTSSVEQMCLVAAFSVSSY--STTVHRIAKPFNPMLGETFEL------D 610
            +  L           ++M  V  + +S++          KP+NP+LGE F+       D
Sbjct: 412 AHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIFQCHWTLPND 471

Query: 611 RLDDMGLRS--------------LCEQVSHHPPSAAHYV--------FSKHGWSLWQEIT 648
             ++  L S              + EQVSHHPP +A Y         F+ H W+      
Sbjct: 472 TEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAHIWT------ 525

Query: 649 ISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIVNHK 708
             SKF G  I +  +G   +       HY+         +I+    W++  G+  I   K
Sbjct: 526 -KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVP-WVELGGECNINCSK 583

Query: 709 TNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSPSSPS 768
           T     + F    ++  +  R    + S +  K+   + G W      + VM++  ++  
Sbjct: 584 TGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEW------NGVMYAKYAT-- 635

Query: 769 SDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRPDQRL 828
             G+      T    ++ KK    E+              NE+E         L  D   
Sbjct: 636 --GENTVFVDTKKLPIIKKKVRKLEDQ-------------NEYE------SRSLWKDVTF 674

Query: 829 MEKGRWDEANTE-KQRLEEKQRLSRRRRLE 857
             K R  +A TE K RLEE+QR   R R E
Sbjct: 675 NLKIRDIDAATEAKHRLEERQRAEARERKE 704


>gi|19923812 oxysterol-binding protein-like protein 10 [Homo
           sapiens]
          Length = 764

 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 183/838 (21%), Positives = 318/838 (37%), Gaps = 152/838 (18%)

Query: 107 GSESSSGVGAGPFTKAASEPLSRAVGSATFLRPESGSLPALKPLPLLRPGQAKTPLGVPM 166
           G  +SS   +   T A S P     G     R  +  L           G   +P  V  
Sbjct: 12  GGSNSSSRSSSRATSAGSSPSCSLAGRGVSSRSAAAGLGG--------GGSRSSPGSVAA 63

Query: 167 S--GTGTTSSAPLALLPLDSFEGWLLKWTNYLKGYQRRWFVLG--NGLLSYYRNQGEMAH 222
           S  G G     P       + EG L K+TN L+G+Q R+FVL    G+L Y+ N+     
Sbjct: 64  SPSGGGGRRREP-------ALEGVLSKYTNLLQGWQNRYFVLDFEAGILQYFVNEQSKHQ 116

Query: 223 TCRGTINLSTAHIDTEDSCG---ILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRV 279
             RG ++LS A +   D      ++ ++    + L+A+   ++Q W+T L  A AK    
Sbjct: 117 KPRGVLSLSGAIVSLSDEAPHMLVVYSANGEMFKLRAADAKEKQFWVTQLR-ACAKYHME 175

Query: 280 MNTHSDDSGDDDEAT-----TPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSL 334
           MN+ S  S      T     TP   S    + ++LS+    + T      K  AA +R+ 
Sbjct: 176 MNSKSAPSSRSRSLTLLPHGTPNSASPC--SQRHLSVGAPGVVTITH--HKSPAAARRAK 231

Query: 335 TELDGLKIPSESGEKLKVVNERATLFRITSNAMINACRDFLELAEIHSRKWQRALQYEQE 394
           ++  G         +L  V E           +++A         + +      L     
Sbjct: 232 SQYSG---------QLHEVREMMNQVEGQQKNLVHAIESLPGSGPLTALDQDLLL----- 277

Query: 395 QRVHLEETIEQLAKQHNSLERAFHSAPGRPANPSKSFIEGSLLTPKGEDSEEDEDTE--Y 452
            +     T+  L +  N L+++ H A G+P+   K     ++L   G  S   E  +   
Sbjct: 278 LKATSAATLSCLGECLNLLQQSVHQA-GQPS--QKPGASENILGWHGSKSHSTEQLKNGT 334

Query: 453 FDAMEDSTSFIT--VITEAKEDSRKAEGSTGTSSVDWSSADNVLDGASLV----PKGSSK 506
             ++  +++ IT  ++  + ED + ++     +S           G+ LV     K  ++
Sbjct: 335 LGSLPSASANITWAILPNSAEDEQTSQPEPEPNS-----------GSELVLSEDEKSDNE 383

Query: 507 VKRRVRI---PNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHL 563
            K    +    ++ +  L+L S +K  +G +L+++ +P    E  S+L+   + + +  L
Sbjct: 384 DKEETELGVMEDQRSIILHLISQLK--LGMDLTKVVLPTFILEKRSLLEMYADFMAHPDL 441

Query: 564 LDKAVHCTSSVEQ--MCLVAAFSVSSYSTTVHRIA-KPFNPMLGETFEL------DRL-- 612
           L  A+   ++ E+  +C V  +  + +      +A KP+NP++GETF        DR+  
Sbjct: 442 L-LAITAGATPEERVICFVEYYLTAFHEGRKGALAKKPYNPIIGETFHCSWEVPKDRVKP 500

Query: 613 -----------------DDMG----LRSLCEQVSHHPPSAAHY--------VFSKHGWSL 643
                            DD      LR + EQVSHHPP +  Y          + H W+ 
Sbjct: 501 KRTASRSPASCHEHPMADDPSKSYKLRFVAEQVSHHPPISCFYCECEEKRLCVNTHVWT- 559

Query: 644 WQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIE 703
                  SKF G  + +  +G   L     G  YV+   ++   +I+    W++  G + 
Sbjct: 560 ------KSKFMGMSVGVSMIGEGVLRLLEHGEEYVFTLPSAYARSILTIP-WVELGGKVS 612

Query: 704 IVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSS 763
           I   KT     + F    ++  +  R    V  +          G W+  +E +      
Sbjct: 613 INCAKTGYSATVIFHTKPFYGGKVHRVTAEVKHNPTNTIVCKAHGEWNGTLEFT------ 666

Query: 764 PSSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLR 823
                ++G+ K +  T       K  PL                    ++G   + +  R
Sbjct: 667 ----YNNGETKVIDTTTLPVYPKKIRPL-------------------EKQGPMESRNLWR 703

Query: 824 PDQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAY-TPLW 880
              R +  G  D A  +K+ LEEKQR+  R+R     P       +E +   Y  PLW
Sbjct: 704 EVTRYLRLGDIDAATEQKRHLEEKQRVEERKRENLRTPWKPKYFIQEGDGWVYFNPLW 761


>gi|22547176 oxysterol binding protein-like 9 isoform f [Homo
           sapiens]
          Length = 746

 Score = 97.4 bits (241), Expect = 5e-20
 Identities = 177/778 (22%), Positives = 286/778 (36%), Gaps = 175/778 (22%)

Query: 186 EGWLLKWTNYLKGYQRRWFVL--GNGLLSYYRNQGEMAH-TCRGTINLSTA--HIDTEDS 240
           EG L KWTN +KG+Q RWFVL    GLLSYY ++ +M   + RG + L  A   ID ED 
Sbjct: 6   EGPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDD 65

Query: 241 CGILLTSGARSYHLKASSEVDRQQWITALE---LAKAKAVRVMNTHSD------------ 285
               +T   +++H +A    +R++WI ALE   L     +++  T +             
Sbjct: 66  STFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQISTTLAFFQSSGISPVLEF 125

Query: 286 ------DSG------DDDEATTPADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRS 333
                 DSG      D D+  T AD + L   ++ L L  D L  C +            
Sbjct: 126 SKIIGLDSGFVPSVQDFDKKLTEAD-AYLQILIEQLKLFDDKLQNCKE------------ 172

Query: 334 LTELDGLKIPSESGEKLKVVNERATLFRITSNAMINA---CRDFLELAE----------- 379
                      E  +K++ + E       T+N+M+ +   C   L++A+           
Sbjct: 173 ----------DEQRKKIETLKE-------TTNSMVESIKHCIVLLQIAKSTINPVDAIYQ 215

Query: 380 -------IHSRKWQRALQYEQEQRVHLEETIEQLAKQHNSLERAFHSAPGRPANPSKSFI 432
                  I +   Q  L  E  Q    E+    L           H  P   +  S    
Sbjct: 216 PSPLEPVISTMPSQTVLPPEPVQLCKSEQRPSSLPVGPVLATLGHHQTPTPNSTGSGHSP 275

Query: 433 EGSLLTPKG----------EDSEEDEDTEYFDAME------------DSTSFITVITEAK 470
             S LT             E S    + E++DA E            DS+   +V+T + 
Sbjct: 276 PSSSLTSPSHVNLSPNTVPEFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSS 335

Query: 471 EDSRKAEGSTGTSSVDWSSADNVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNC 530
             +      T T S++ SS  N    A L      +         + + S+ +  + +  
Sbjct: 336 SGNSLKRPDT-TESLN-SSLSNGTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVR 393

Query: 531 IGRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSY-- 588
           +G +L+++ +P    E  S+L+   +   +  L           ++M  V  + +S++  
Sbjct: 394 LGMDLTKVVLPTFILERRSLLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHA 453

Query: 589 STTVHRIAKPFNPMLGETFEL------DRLDDMGLRS--------------LCEQVSHHP 628
                   KP+NP+LGE F+       D  ++  L S              + EQVSHHP
Sbjct: 454 GRKGSVAKKPYNPILGEIFQCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHP 513

Query: 629 PSAAHYV--------FSKHGWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWR 680
           P +A Y         F+ H W+        SKF G  I +  +G   +       HY+  
Sbjct: 514 PISAFYAECFNKKIQFNAHIWT-------KSKFLGMSIGVHNIGQGCVSCLDYDEHYILT 566

Query: 681 KSTSTVHNIIVGKLWIDQSGDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQG 740
                  +I+    W++  G+  I   KT     + F    ++  +  R    + S +  
Sbjct: 567 FPNGYGRSILTVP-WVELGGECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDK 625

Query: 741 KAHYVLSGSWDEQMECSKVMHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYY 800
           K+   + G W      + VM++  ++    G+      T    ++ KK    E+      
Sbjct: 626 KSFCSIEGEW------NGVMYAKYAT----GENTVFVDTKKLPIIKKKVRKLEDQ----- 670

Query: 801 FSELALTLNEHEEGVAPTDSRLRPDQRLMEKGRWDEANTE-KQRLEEKQRLSRRRRLE 857
                   NE+E         L  D     K R  +A TE K RLEE+QR   R R E
Sbjct: 671 --------NEYE------SRSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKE 714


>gi|51243032 oxysterol-binding protein-like protein 8 isoform b
           [Homo sapiens]
          Length = 847

 Score = 92.8 bits (229), Expect = 1e-18
 Identities = 129/547 (23%), Positives = 218/547 (39%), Gaps = 88/547 (16%)

Query: 378 AEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHN-------------SLERA--FHSAPG 422
           +E   R W  AL+   +    L+ T+ +  K+H+              L RA   HS   
Sbjct: 207 SESDGRCWMDALELALKCSSLLKRTMIREGKEHDLSVSSDSTHVTFYGLLRANNLHSGDN 266

Query: 423 RPANPSK----SFIEGSLLTPKGE---DSEEDE-DTEYFDAMEDSTSFITVITEAKEDS- 473
              N S+     F +  + + K +   D E DE D E     E+S    T  +E ++DS 
Sbjct: 267 FQLNDSEIERQHFKDQDMYSDKSDKENDQEHDESDNEVMGKSEESD---TDTSERQDDSY 323

Query: 474 ---RKAEGSTGTSSVDWSSADNVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNC 530
                 E    T+  + S  +           G +    +    ++ N SL +W+++K  
Sbjct: 324 IEPEPVEPLKETTYTEQSHEE----------LGEAGEASQTETVSEENKSL-IWTLLKQV 372

Query: 531 I-GRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYS 589
             G +LS++ +P    EP S L +L++   +   L +A    +   ++  V  + +S + 
Sbjct: 373 RPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFY 432

Query: 590 TTVHRIAKPFNPMLGETFE---LDRLDDMGLRSLCEQVSHHPPSAAHYVFS-KHGWSLWQ 645
                + KP+NP+LGETF    +    +     + EQVSHHPP +A YV + K G+ L  
Sbjct: 433 KKPKGLKKPYNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSG 492

Query: 646 EITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIV 705
            I   SKF G  +S +  G   L F   G  YV     +    I+ G + ++  G + I 
Sbjct: 493 SILAKSKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNIT 552

Query: 706 NHKTNDRCQLKFLPYSYF-SKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSP 764
             KT     L+F    +  S +   +++G +   + +    L G WD ++          
Sbjct: 553 CQKTGYSAILEFKLKPFLGSSDCVNQISGKLKLGK-EVLATLEGHWDSEVFI-------- 603

Query: 765 SSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRP 824
                     T  +T ++++ W   P      ++  +  +  T+   E+G   ++   + 
Sbjct: 604 ----------TDKKTDNSEVFWNPTP------DIKQWRLIRHTVKFEEQGDFESEKLWQR 647

Query: 825 DQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKR 884
             R +      EA  EK  LEE QR + R R          +  EE     +        
Sbjct: 648 VTRAINAKDQTEATQEKYVLEEAQRQAARDRK---------TKNEEWSCKLF-------E 691

Query: 885 LDPLTGE 891
           LDPLTGE
Sbjct: 692 LDPLTGE 698


>gi|18079218 oxysterol-binding protein-like protein 8 isoform a
           [Homo sapiens]
          Length = 889

 Score = 92.8 bits (229), Expect = 1e-18
 Identities = 129/547 (23%), Positives = 218/547 (39%), Gaps = 88/547 (16%)

Query: 378 AEIHSRKWQRALQYEQEQRVHLEETIEQLAKQHN-------------SLERA--FHSAPG 422
           +E   R W  AL+   +    L+ T+ +  K+H+              L RA   HS   
Sbjct: 249 SESDGRCWMDALELALKCSSLLKRTMIREGKEHDLSVSSDSTHVTFYGLLRANNLHSGDN 308

Query: 423 RPANPSK----SFIEGSLLTPKGE---DSEEDE-DTEYFDAMEDSTSFITVITEAKEDS- 473
              N S+     F +  + + K +   D E DE D E     E+S    T  +E ++DS 
Sbjct: 309 FQLNDSEIERQHFKDQDMYSDKSDKENDQEHDESDNEVMGKSEESD---TDTSERQDDSY 365

Query: 474 ---RKAEGSTGTSSVDWSSADNVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNC 530
                 E    T+  + S  +           G +    +    ++ N SL +W+++K  
Sbjct: 366 IEPEPVEPLKETTYTEQSHEE----------LGEAGEASQTETVSEENKSL-IWTLLKQV 414

Query: 531 I-GRELSRIPMPVNFNEPLSMLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYS 589
             G +LS++ +P    EP S L +L++   +   L +A    +   ++  V  + +S + 
Sbjct: 415 RPGMDLSKVVLPTFILEPRSFLDKLSDYYYHADFLSEAALEENPYFRLKKVVKWYLSGFY 474

Query: 590 TTVHRIAKPFNPMLGETFE---LDRLDDMGLRSLCEQVSHHPPSAAHYVFS-KHGWSLWQ 645
                + KP+NP+LGETF    +    +     + EQVSHHPP +A YV + K G+ L  
Sbjct: 475 KKPKGLKKPYNPILGETFRCLWIHPRTNSKTFYIAEQVSHHPPISAFYVSNRKDGFCLSG 534

Query: 646 EITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQSGDIEIV 705
            I   SKF G  +S +  G   L F   G  YV     +    I+ G + ++  G + I 
Sbjct: 535 SILAKSKFYGNSLSAILEGEARLTFLNRGEDYVMTMPYAHCKGILYGTMTLELGGTVNIT 594

Query: 706 NHKTNDRCQLKFLPYSYF-SKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKVMHSSP 764
             KT     L+F    +  S +   +++G +   + +    L G WD ++          
Sbjct: 595 CQKTGYSAILEFKLKPFLGSSDCVNQISGKLKLGK-EVLATLEGHWDSEVFI-------- 645

Query: 765 SSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTDSRLRP 824
                     T  +T ++++ W   P      ++  +  +  T+   E+G   ++   + 
Sbjct: 646 ----------TDKKTDNSEVFWNPTP------DIKQWRLIRHTVKFEEQGDFESEKLWQR 689

Query: 825 DQRLMEKGRWDEANTEKQRLEEKQRLSRRRRLEACGPGSSCSSEEEKEADAYTPLWFEKR 884
             R +      EA  EK  LEE QR + R R          +  EE     +        
Sbjct: 690 VTRAINAKDQTEATQEKYVLEEAQRQAARDRK---------TKNEEWSCKLF-------E 733

Query: 885 LDPLTGE 891
           LDPLTGE
Sbjct: 734 LDPLTGE 740


>gi|54792084 pleckstrin homology domain containing, family A
           (phosphoinositide binding specific) member 3 [Homo
           sapiens]
          Length = 300

 Score = 87.4 bits (215), Expect = 5e-17
 Identities = 55/196 (28%), Positives = 93/196 (47%), Gaps = 23/196 (11%)

Query: 186 EGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTEDSCGI-- 243
           EG L KWTNYL G+Q RWFVL NG+LSYY +Q ++    +G+I ++   I    +     
Sbjct: 2   EGVLYKWTNYLTGWQPRWFVLDNGILSYYDSQDDVCKGSKGSIKMAVCEIKVHSADNTRM 61

Query: 244 -LLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSEL 302
            L+  G + +++KA +  +RQ+W+ AL  +KA                   T    + E+
Sbjct: 62  ELIIPGEQHFYMKAVNAAERQRWLVALGSSKACLT---------------DTRTKKEKEI 106

Query: 303 HHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRI 362
             T ++L  K+ +L    DL+ +    +Q  +   +    PS        +NE ++L   
Sbjct: 107 SETSESLKTKMSELRLYCDLLMQQVHTIQEFVHHDENHSSPSAEN-----MNEASSLLSA 161

Query: 363 TSNAMINACRDFLELA 378
           T N  I    + +++A
Sbjct: 162 TCNTFITTLEECVKIA 177


>gi|194294543 alpha 3 type IV collagen binding protein isoform 3
           [Homo sapiens]
          Length = 752

 Score = 84.0 bits (206), Expect = 6e-16
 Identities = 97/394 (24%), Positives = 157/394 (39%), Gaps = 71/394 (18%)

Query: 187 GWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTED--SCGIL 244
           G L KWTNY+ G+Q RW VL N  LSYY+++ E  + CRG+I LS A I   D   C   
Sbjct: 156 GVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDETEYGCRGSICLSKAVITPHDFDECRFD 215

Query: 245 LTSGARSYHLKASSEVDRQQWITALELAKAKAV--------RVMNTHSDDSGDDDEATTP 296
           ++     ++L+A     RQQWI A+E  K ++         R  +  S  SG    + T 
Sbjct: 216 ISVNDSVWYLRAQDPDHRQQWIDAIEQHKTESGYGSESSLRRHGSMVSLVSGASGYSATS 275

Query: 297 ADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSL---------------------- 334
               +  H+L+    KL ++ T  D++ +    LQ+                        
Sbjct: 276 TSSFKKGHSLRE---KLAEMETFRDILCRQVDTLQKYFDACADAVSKDELQRDKVVEDDE 332

Query: 335 -----TELDGLKIPSESGEKLKVVNE-------------RATLFRITSNAMINACRDFLE 376
                T  DG  + S +G K K+                 A  F+ T+  ++      +E
Sbjct: 333 DDFPTTRSDGDFLHSTNGNKEKLFPHVTPKGINGIDFKGEAITFKATTAGILATLSHCIE 392

Query: 377 LAEIHSRKWQRALQYEQEQRVHLEE----TIEQLAKQHNSLERAFHSAPGRPANPSKSFI 432
           L       WQ+ L  E E++   EE     + +L K+ +     +   P    N  + F 
Sbjct: 393 LMVKREDSWQKRLDKETEKKRRTEEAYKNAMTELKKKSHFGGPDYEEGPNSLINEEEFFD 452

Query: 433 EGSLLTPKGEDSEEDEDTE-----YFDAMEDSTSFITVITEAKEDSRKAEGSTGTSSVDW 487
                  + +  EE   +E     +  ++    +F +V T  +   +    S+  SS+D 
Sbjct: 453 AVEAALDRQDKIEEQSQSEKVRLHWPTSLPSGDAFSSVGTH-RFVQKPYSRSSSMSSIDL 511

Query: 488 SSADNVLDGASLVPKGSSKVKRRVRIPNKPNYSL 521
            SA +       V + SS+V+  V+  N   YSL
Sbjct: 512 VSASDD------VHRFSSQVEEMVQ--NHMTYSL 537


>gi|5031717 alpha 3 type IV collagen binding protein isoform 1 [Homo
           sapiens]
          Length = 624

 Score = 84.0 bits (206), Expect = 6e-16
 Identities = 97/394 (24%), Positives = 157/394 (39%), Gaps = 71/394 (18%)

Query: 187 GWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTED--SCGIL 244
           G L KWTNY+ G+Q RW VL N  LSYY+++ E  + CRG+I LS A I   D   C   
Sbjct: 28  GVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDETEYGCRGSICLSKAVITPHDFDECRFD 87

Query: 245 LTSGARSYHLKASSEVDRQQWITALELAKAKAV--------RVMNTHSDDSGDDDEATTP 296
           ++     ++L+A     RQQWI A+E  K ++         R  +  S  SG    + T 
Sbjct: 88  ISVNDSVWYLRAQDPDHRQQWIDAIEQHKTESGYGSESSLRRHGSMVSLVSGASGYSATS 147

Query: 297 ADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSL---------------------- 334
               +  H+L+    KL ++ T  D++ +    LQ+                        
Sbjct: 148 TSSFKKGHSLRE---KLAEMETFRDILCRQVDTLQKYFDACADAVSKDELQRDKVVEDDE 204

Query: 335 -----TELDGLKIPSESGEKLKVVNE-------------RATLFRITSNAMINACRDFLE 376
                T  DG  + S +G K K+                 A  F+ T+  ++      +E
Sbjct: 205 DDFPTTRSDGDFLHSTNGNKEKLFPHVTPKGINGIDFKGEAITFKATTAGILATLSHCIE 264

Query: 377 LAEIHSRKWQRALQYEQEQRVHLEE----TIEQLAKQHNSLERAFHSAPGRPANPSKSFI 432
           L       WQ+ L  E E++   EE     + +L K+ +     +   P    N  + F 
Sbjct: 265 LMVKREDSWQKRLDKETEKKRRTEEAYKNAMTELKKKSHFGGPDYEEGPNSLINEEEFFD 324

Query: 433 EGSLLTPKGEDSEEDEDTE-----YFDAMEDSTSFITVITEAKEDSRKAEGSTGTSSVDW 487
                  + +  EE   +E     +  ++    +F +V T  +   +    S+  SS+D 
Sbjct: 325 AVEAALDRQDKIEEQSQSEKVRLHWPTSLPSGDAFSSVGTH-RFVQKPYSRSSSMSSIDL 383

Query: 488 SSADNVLDGASLVPKGSSKVKRRVRIPNKPNYSL 521
            SA +       V + SS+V+  V+  N   YSL
Sbjct: 384 VSASDD------VHRFSSQVEEMVQ--NHMTYSL 409


>gi|14165452 alpha 3 type IV collagen binding protein isoform 2
           [Homo sapiens]
          Length = 598

 Score = 82.4 bits (202), Expect = 2e-15
 Identities = 79/319 (24%), Positives = 125/319 (39%), Gaps = 57/319 (17%)

Query: 187 GWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTED--SCGIL 244
           G L KWTNY+ G+Q RW VL N  LSYY+++ E  + CRG+I LS A I   D   C   
Sbjct: 28  GVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDETEYGCRGSICLSKAVITPHDFDECRFD 87

Query: 245 LTSGARSYHLKASSEVDRQQWITALELAKAKAV--------RVMNTHSDDSGDDDEATTP 296
           ++     ++L+A     RQQWI A+E  K ++         R  +  S  SG    + T 
Sbjct: 88  ISVNDSVWYLRAQDPDHRQQWIDAIEQHKTESGYGSESSLRRHGSMVSLVSGASGYSATS 147

Query: 297 ADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSL---------------------- 334
               +  H+L+    KL ++ T  D++ +    LQ+                        
Sbjct: 148 TSSFKKGHSLRE---KLAEMETFRDILCRQVDTLQKYFDACADAVSKDELQRDKVVEDDE 204

Query: 335 -----TELDGLKIPSESGEKLKVVNE-------------RATLFRITSNAMINACRDFLE 376
                T  DG  + S +G K K+                 A  F+ T+  ++      +E
Sbjct: 205 DDFPTTRSDGDFLHSTNGNKEKLFPHVTPKGINGIDFKGEAITFKATTAGILATLSHCIE 264

Query: 377 LAEIHSRKWQRALQYEQEQRVHLEE----TIEQLAKQHNSLERAFHSAPGRPANPSKSFI 432
           L       WQ+ L  E E++   EE     + +L K+ +     +   P    N  + F 
Sbjct: 265 LMVKREDSWQKRLDKETEKKRRTEEAYKNAMTELKKKSHFGGPDYEEGPNSLINEEEFFD 324

Query: 433 EGSLLTPKGEDSEEDEDTE 451
                  + +  EE   +E
Sbjct: 325 AVEAALDRQDKIEEQSQSE 343


>gi|14249174 pleckstrin homology domain containing, family A
           (phosphoinositide binding specific) member 8 [Homo
           sapiens]
          Length = 440

 Score = 78.2 bits (191), Expect = 3e-14
 Identities = 58/196 (29%), Positives = 94/196 (47%), Gaps = 27/196 (13%)

Query: 186 EGWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHI---DTEDSCG 242
           EG L KWTNYL G+Q RWF+L  G+LSYY +  +    C+G+I ++   I     +++  
Sbjct: 2   EGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTRM 61

Query: 243 ILLTSGARSYHLKASSEVDRQQWITALELAKAKAVRVMNTHSDDSGDDDEATTPADKSEL 302
            L+  G + ++LKA S  +RQ+W+ AL  AKA                 ++ T  +K E 
Sbjct: 62  DLIIPGEQYFYLKARSVAERQRWLVALGSAKACLT--------------DSRTQKEK-EF 106

Query: 303 HHTLKNLSLKLDDLSTCNDLIAKHGAALQRSLTELDGLKIPSESGEKLKVVNERATLFRI 362
               +NL  K+ +L    DL+ +     +   T   G+   S S E + V     TL + 
Sbjct: 107 AENTENLKTKMSELRLYCDLLVQQVDKTKEVTT--TGV---SNSEEGIDV----GTLLKS 157

Query: 363 TSNAMINACRDFLELA 378
           T N  +    + +++A
Sbjct: 158 TCNTFLKTLEECMQIA 173


>gi|22547171 oxysterol binding protein-like 9 isoform c [Homo
           sapiens]
          Length = 626

 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 100/459 (21%), Positives = 171/459 (37%), Gaps = 82/459 (17%)

Query: 442 EDSEEDEDTEYFDAME------------DSTSFITVITEAKEDSRKAEGSTGTSSVDWSS 489
           E S    + E++DA E            DS+   +V+T +   +      T T S++ SS
Sbjct: 175 EFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDT-TESLN-SS 232

Query: 490 ADNVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLS 549
             N    A L      +         + + S+ +  + +  +G +L+++ +P    E  S
Sbjct: 233 LSNGTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRS 292

Query: 550 MLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIA--KPFNPMLGETF 607
           +L+   +   +  L           ++M  V  + +S++          KP+NP+LGE F
Sbjct: 293 LLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIF 352

Query: 608 EL------DRLDDMGLRS--------------LCEQVSHHPPSAAHYV--------FSKH 639
           +       D  ++  L S              + EQVSHHPP +A Y         F+ H
Sbjct: 353 QCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAH 412

Query: 640 GWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQS 699
            W+        SKF G  I +  +G   +       HY+         +I+    W++  
Sbjct: 413 IWT-------KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVP-WVELG 464

Query: 700 GDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKV 759
           G+  I   KT     + F    ++  +  R    + S +  K+   + G W      + V
Sbjct: 465 GECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEW------NGV 518

Query: 760 MHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTD 819
           M++  ++    G+      T    ++ KK    E+              NE+E       
Sbjct: 519 MYAKYAT----GENTVFVDTKKLPIIKKKVRKLEDQ-------------NEYE------S 555

Query: 820 SRLRPDQRLMEKGRWDEANTE-KQRLEEKQRLSRRRRLE 857
             L  D     K R  +A TE K RLEE+QR   R R E
Sbjct: 556 RSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKE 594


>gi|22547169 oxysterol binding protein-like 9 isoform b [Homo
           sapiens]
          Length = 571

 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 100/459 (21%), Positives = 171/459 (37%), Gaps = 82/459 (17%)

Query: 442 EDSEEDEDTEYFDAME------------DSTSFITVITEAKEDSRKAEGSTGTSSVDWSS 489
           E S    + E++DA E            DS+   +V+T +   +      T T S++ SS
Sbjct: 120 EFSYSSSEDEFYDADEFHQSGSSPKRLIDSSGSASVLTHSSSGNSLKRPDT-TESLN-SS 177

Query: 490 ADNVLDGASLVPKGSSKVKRRVRIPNKPNYSLNLWSIMKNCIGRELSRIPMPVNFNEPLS 549
             N    A L      +         + + S+ +  + +  +G +L+++ +P    E  S
Sbjct: 178 LSNGTSDADLFDSHDDRDDDAEAGSVEEHKSVIMHLLSQVRLGMDLTKVVLPTFILERRS 237

Query: 550 MLQRLTEDLEYHHLLDKAVHCTSSVEQMCLVAAFSVSSYSTTVHRIA--KPFNPMLGETF 607
           +L+   +   +  L           ++M  V  + +S++          KP+NP+LGE F
Sbjct: 238 LLEMYADFFAHPDLFVSISDQKDPKDRMVQVVKWYLSAFHAGRKGSVAKKPYNPILGEIF 297

Query: 608 EL------DRLDDMGLRS--------------LCEQVSHHPPSAAHYV--------FSKH 639
           +       D  ++  L S              + EQVSHHPP +A Y         F+ H
Sbjct: 298 QCHWTLPNDTEENTELVSEGPVPWVSKNSVTFVAEQVSHHPPISAFYAECFNKKIQFNAH 357

Query: 640 GWSLWQEITISSKFRGKYISIMPLGAIHLEFQASGNHYVWRKSTSTVHNIIVGKLWIDQS 699
            W+        SKF G  I +  +G   +       HY+         +I+    W++  
Sbjct: 358 IWT-------KSKFLGMSIGVHNIGQGCVSCLDYDEHYILTFPNGYGRSILTVP-WVELG 409

Query: 700 GDIEIVNHKTNDRCQLKFLPYSYFSKEAARKVTGVVSDSQGKAHYVLSGSWDEQMECSKV 759
           G+  I   KT     + F    ++  +  R    + S +  K+   + G W      + V
Sbjct: 410 GECNINCSKTGYSANIIFHTKPFYGGKKHRITAEIFSPNDKKSFCSIEGEW------NGV 463

Query: 760 MHSSPSSPSSDGKQKTVYQTLSAKLLWKKYPLPENAENMYYFSELALTLNEHEEGVAPTD 819
           M++  ++    G+      T    ++ KK    E+              NE+E       
Sbjct: 464 MYAKYAT----GENTVFVDTKKLPIIKKKVRKLEDQ-------------NEYE------S 500

Query: 820 SRLRPDQRLMEKGRWDEANTE-KQRLEEKQRLSRRRRLE 857
             L  D     K R  +A TE K RLEE+QR   R R E
Sbjct: 501 RSLWKDVTFNLKIRDIDAATEAKHRLEERQRAEARERKE 539


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.129    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,956,015
Number of Sequences: 37866
Number of extensions: 2043417
Number of successful extensions: 14489
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 121
Number of HSP's successfully gapped in prelim test: 611
Number of HSP's that attempted gapping in prelim test: 11621
Number of HSP's gapped (non-prelim): 2641
length of query: 916
length of database: 18,247,518
effective HSP length: 111
effective length of query: 805
effective length of database: 14,044,392
effective search space: 11305735560
effective search space used: 11305735560
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.