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Search of human proteins with 6005872
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6005872 SEC63-like protein [Homo sapiens]
(760 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6005872 SEC63-like protein [Homo sapiens] 1534 0.0
gi|40217847 activating signal cointegrator 1 complex subunit 3-l... 74 4e-13
gi|239756904 PREDICTED: similar to SNRNP200 protein [Homo sapiens] 69 2e-11
gi|169218225 PREDICTED: similar to U5 snRNP-specific 200kD prote... 67 8e-11
gi|194306642 DnaJ (Hsp40) homolog, subfamily B, member 12 [Homo ... 62 3e-09
gi|194306640 DnaJ (Hsp40) homolog, subfamily B, member 12 [Homo ... 62 3e-09
gi|56687498 DnaJ (Hsp40) homolog, subfamily C, member 16 [Homo s... 61 3e-09
gi|239745928 PREDICTED: hypothetical protein XP_002343618 [Homo ... 59 1e-08
gi|112293277 DnaJ (Hsp40) homolog, subfamily C, member 8 [Homo s... 58 4e-08
gi|4504511 DnaJ (Hsp40) homolog, subfamily A, member 1 [Homo sap... 57 5e-08
gi|45504382 DnaJ (Hsp40) homolog, subfamily C, member 5 [Homo sa... 57 6e-08
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 57 8e-08
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 57 8e-08
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 57 8e-08
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 57 8e-08
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 57 8e-08
gi|194328760 DnaJ (Hsp40) homolog, subfamily A, member 4 isoform... 57 8e-08
gi|194328758 DnaJ (Hsp40) homolog, subfamily A, member 4 isoform... 57 8e-08
gi|201862587 DnaJ (Hsp40) homolog, subfamily B, member 5 isoform... 56 1e-07
gi|201862518 DnaJ (Hsp40) homolog, subfamily B, member 5 isoform... 56 1e-07
gi|29126218 DnaJ (Hsp40) homolog, subfamily C, member 5 beta [Ho... 56 1e-07
gi|56549115 DnaJ (Hsp40) homolog, subfamily B, member 5 isoform ... 55 2e-07
gi|76880486 activating signal cointegrator 1 complex subunit 3 i... 55 3e-07
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 55 3e-07
gi|72534740 DnaJ (Hsp40) homolog, subfamily B, member 14 isoform... 54 5e-07
gi|205360840 DnaJ (Hsp40) homolog, subfamily A, member 3 isoform... 53 9e-07
gi|205360838 DnaJ (Hsp40) homolog, subfamily A, member 3 isoform... 53 9e-07
gi|5453690 DnaJ (Hsp40) homolog, subfamily B, member 1 [Homo sap... 53 1e-06
gi|18093112 ABT1-associated protein [Homo sapiens] 53 1e-06
gi|22749377 DnaJ (Hsp40) homolog, subfamily C, member 18 [Homo s... 52 2e-06
>gi|6005872 SEC63-like protein [Homo sapiens]
Length = 760
Score = 1534 bits (3971), Expect = 0.0
Identities = 760/760 (100%), Positives = 760/760 (100%)
Query: 1 MAGQQFQYDDSGNTFFYFLTSFVGLIVIPATYYLWPRDQNAEQIRLKNIRKVYGRCMWYR 60
MAGQQFQYDDSGNTFFYFLTSFVGLIVIPATYYLWPRDQNAEQIRLKNIRKVYGRCMWYR
Sbjct: 1 MAGQQFQYDDSGNTFFYFLTSFVGLIVIPATYYLWPRDQNAEQIRLKNIRKVYGRCMWYR 60
Query: 61 LRLLKPQPNIIPTVKKIVLLAGWALFLFLAYKVSKTDREYQEYNPYEVLNLDPGATVAEI 120
LRLLKPQPNIIPTVKKIVLLAGWALFLFLAYKVSKTDREYQEYNPYEVLNLDPGATVAEI
Sbjct: 61 LRLLKPQPNIIPTVKKIVLLAGWALFLFLAYKVSKTDREYQEYNPYEVLNLDPGATVAEI 120
Query: 121 KKQYRLLSLKYHPDKGGDEVMFMRIAKAYAALTDEESRKNWEEFGNPDGPQATSFGIALP 180
KKQYRLLSLKYHPDKGGDEVMFMRIAKAYAALTDEESRKNWEEFGNPDGPQATSFGIALP
Sbjct: 121 KKQYRLLSLKYHPDKGGDEVMFMRIAKAYAALTDEESRKNWEEFGNPDGPQATSFGIALP 180
Query: 181 AWIVDQKNSILVLLVYGLAFMVILPVVVGSWWYRSIRYSGDQILIRTTQIYTYFVYKTRN 240
AWIVDQKNSILVLLVYGLAFMVILPVVVGSWWYRSIRYSGDQILIRTTQIYTYFVYKTRN
Sbjct: 181 AWIVDQKNSILVLLVYGLAFMVILPVVVGSWWYRSIRYSGDQILIRTTQIYTYFVYKTRN 240
Query: 241 MDMKRLIMVLAGASEFDPQYNKDATSRPTDNILIPQLIREIGSINLKKNEPPLTCPYSLK 300
MDMKRLIMVLAGASEFDPQYNKDATSRPTDNILIPQLIREIGSINLKKNEPPLTCPYSLK
Sbjct: 241 MDMKRLIMVLAGASEFDPQYNKDATSRPTDNILIPQLIREIGSINLKKNEPPLTCPYSLK 300
Query: 301 ARVLLLSHLARMKIPETLEEDQQFMLKKCPALLQEMVNVICQLIVMARNREEREFRAPTL 360
ARVLLLSHLARMKIPETLEEDQQFMLKKCPALLQEMVNVICQLIVMARNREEREFRAPTL
Sbjct: 301 ARVLLLSHLARMKIPETLEEDQQFMLKKCPALLQEMVNVICQLIVMARNREEREFRAPTL 360
Query: 361 ASLENCMKLSQMAVQGLQQFKSPLLQLPHIEEDNLRRVSNHKKYKIKTIQDLVSLKESDR 420
ASLENCMKLSQMAVQGLQQFKSPLLQLPHIEEDNLRRVSNHKKYKIKTIQDLVSLKESDR
Sbjct: 361 ASLENCMKLSQMAVQGLQQFKSPLLQLPHIEEDNLRRVSNHKKYKIKTIQDLVSLKESDR 420
Query: 421 HTLLHFLEDEKYEEVMAVLGSFPYVTMDIKSQVLDDEDSNNITVGSLVTVLVKLTRQTMA 480
HTLLHFLEDEKYEEVMAVLGSFPYVTMDIKSQVLDDEDSNNITVGSLVTVLVKLTRQTMA
Sbjct: 421 HTLLHFLEDEKYEEVMAVLGSFPYVTMDIKSQVLDDEDSNNITVGSLVTVLVKLTRQTMA 480
Query: 481 EVFEKEQSICAAEEQPAEDGQGETNKNRTKGGWQQKSKGPKKTAKSKKKKPLKKKPTPVL 540
EVFEKEQSICAAEEQPAEDGQGETNKNRTKGGWQQKSKGPKKTAKSKKKKPLKKKPTPVL
Sbjct: 481 EVFEKEQSICAAEEQPAEDGQGETNKNRTKGGWQQKSKGPKKTAKSKKKKPLKKKPTPVL 540
Query: 541 LPQSKQQKQKQANGVVGNEAAVKEDEEEVSDKGSDSEEEETNRDSQSEKDDGSDRDSDRE 600
LPQSKQQKQKQANGVVGNEAAVKEDEEEVSDKGSDSEEEETNRDSQSEKDDGSDRDSDRE
Sbjct: 541 LPQSKQQKQKQANGVVGNEAAVKEDEEEVSDKGSDSEEEETNRDSQSEKDDGSDRDSDRE 600
Query: 601 QDEKQNKDDEAEWQELQQSIQRKERALLETKSKITHPVYSLYFPEEKQEWWWLYIADRKE 660
QDEKQNKDDEAEWQELQQSIQRKERALLETKSKITHPVYSLYFPEEKQEWWWLYIADRKE
Sbjct: 601 QDEKQNKDDEAEWQELQQSIQRKERALLETKSKITHPVYSLYFPEEKQEWWWLYIADRKE 660
Query: 661 QTLISMPYHVCTLKDTEEVELKFPAPGKPGNYQYTVFLRSDSYMGLDQIKPLKLEVHEAK 720
QTLISMPYHVCTLKDTEEVELKFPAPGKPGNYQYTVFLRSDSYMGLDQIKPLKLEVHEAK
Sbjct: 661 QTLISMPYHVCTLKDTEEVELKFPAPGKPGNYQYTVFLRSDSYMGLDQIKPLKLEVHEAK 720
Query: 721 PVPENHPQWDTAIEGDEDQEDSEGFEDSFEEEEEEEEDDD 760
PVPENHPQWDTAIEGDEDQEDSEGFEDSFEEEEEEEEDDD
Sbjct: 721 PVPENHPQWDTAIEGDEDQEDSEGFEDSFEEEEEEEEDDD 760
>gi|40217847 activating signal cointegrator 1 complex subunit 3-like 1
[Homo sapiens]
Length = 2136
Score = 74.3 bits (181), Expect = 4e-13
Identities = 63/253 (24%), Positives = 128/253 (50%), Gaps = 32/253 (12%)
Query: 225 IRTTQIYTYFVYKTRNMDMKRLIMVLAGASEFDPQYNKDATSRPTDNILIPQLIREIGSI 284
I T I + + ++ LI +++ A+E++ + R ++ L+ QL +++
Sbjct: 1824 INYTTIELFSMSLNAKTKVRGLIEIISNAAEYE-----NIPIRHHEDNLLRQLAQKVPH- 1877
Query: 285 NLKKNEPPLTCPYSLKARVLLLSHLARMKIPETLEEDQQFMLKKCPALLQEMVNVICQLI 344
K N P P+ +K +LL +HL+RM++ L+ D + +L K L+Q V+V+
Sbjct: 1878 --KLNNPKFNDPH-VKTNLLLQAHLSRMQLSAELQSDTEEILSKAIRLIQACVDVL---- 1930
Query: 345 VMARNREEREFRAPTLASLENCMKLSQMAVQGLQQFKSPLLQLPHIEEDNLRRVSNHKKY 404
+ +P LA++E L+QM Q + S L QLPH ++++R ++
Sbjct: 1931 ------SSNGWLSPALAAME----LAQMVTQAMWSKDSYLKQLPHFTSEHIKRCTDK--- 1977
Query: 405 KIKTIQDLVSLKESDRHTLLHFLEDEKYEEVMAVLGSFPYVTMDIKSQVLDDEDSNNITV 464
++++ D++ +++ +R+ LL L D + +V +P +++ +V+ D ++I
Sbjct: 1978 GVESVFDIMEMEDEERNALLQ-LTDSQIADVARFCNRYP--NIELSYEVV---DKDSIRS 2031
Query: 465 GSLVTVLVKLTRQ 477
G V VLV+L R+
Sbjct: 2032 GGPVVVLVQLERE 2044
Score = 69.3 bits (168), Expect = 1e-11
Identities = 36/93 (38%), Positives = 57/93 (61%), Gaps = 3/93 (3%)
Query: 628 LETKSKITHPVYSLYFPEEKQEWWWLYIADRKEQTLISMPYHVCTLKDTEEVELKFPAPG 687
LE + ++T PV + FP++++E WW+ I D K +LIS+ TL+ +V+L F AP
Sbjct: 2041 LEREEEVTGPVIAPLFPQKREEGWWVVIGDAKSNSLISIKR--LTLQQKAKVKLDFVAPA 2098
Query: 688 KPGNYQYTVFLRSDSYMGLDQIKPLKLEVHEAK 720
G + YT++ SD+YMG DQ ++V EA+
Sbjct: 2099 -TGAHNYTLYFMSDAYMGCDQEYKFSVDVKEAE 2130
>gi|239756904 PREDICTED: similar to SNRNP200 protein [Homo sapiens]
Length = 302
Score = 68.6 bits (166), Expect = 2e-11
Identities = 38/130 (29%), Positives = 70/130 (53%), Gaps = 3/130 (2%)
Query: 591 DGSDRDSDREQDEKQNKDDEAEWQELQQSIQRKERALLETKSKITHPVYSLYFPEEKQEW 650
+ +R++ + + Q D+ + ++ LE + ++T PV + FP++++E
Sbjct: 170 EDEERNTILQLTDSQITDEVVDKDSIRSGGPAVVLVQLEREEEVTGPVIAPLFPQKREEG 229
Query: 651 WWLYIADRKEQTLISMPYHVCTLKDTEEVELKFPAPGKPGNYQYTVFLRSDSYMGLDQIK 710
WW+ I D K +LIS+ + L+ +V+L F AP G + YT++ SD+YMG DQ
Sbjct: 230 WWVVIGDTKSNSLISIKRLI--LQQKAKVKLDFVAPA-TGAHNYTLYFMSDAYMGCDQEY 286
Query: 711 PLKLEVHEAK 720
++V EA+
Sbjct: 287 KFSMDVKEAE 296
Score = 62.8 bits (151), Expect = 1e-09
Identities = 48/191 (25%), Positives = 90/191 (47%), Gaps = 39/191 (20%)
Query: 287 KKNEPPLTCPYSLKARVLLLSHLARMKIPETLEEDQQFMLKKCPALLQEMVNVICQLIVM 346
K N P P+ +K +LL +HL+RM++ L+ D + +L K L+Q V+V+
Sbjct: 59 KLNNPKFNDPH-IKTNLLLQAHLSRMQLSAELQSDTEEILSKAVRLVQACVDVLSS---- 113
Query: 347 ARNREEREFRAPTLASLENCMKLSQMAVQGLQQFKSPLLQLPHIEEDNLRRVSNHKKYKI 406
L+S M+L+QM Q + S L QLPH ++++R ++ +
Sbjct: 114 ----------NGWLSSALAAMELAQMVTQAMWSKDSYLKQLPHFISEHIKRCTDK---GV 160
Query: 407 KTIQDLVSLKESDRHTLLHFLEDEKYEEVMAVLGSFPYVTMDIKSQVLDDEDSNNITVGS 466
K++ D++ +++ +R+T+L + + +EV+ D ++I G
Sbjct: 161 KSVFDIMEMEDEERNTILQLTDSQITDEVV---------------------DKDSIRSGG 199
Query: 467 LVTVLVKLTRQ 477
VLV+L R+
Sbjct: 200 PAVVLVQLERE 210
>gi|169218225 PREDICTED: similar to U5 snRNP-specific 200kD protein,
partial [Homo sapiens]
Length = 1700
Score = 66.6 bits (161), Expect = 8e-11
Identities = 35/93 (37%), Positives = 56/93 (60%), Gaps = 3/93 (3%)
Query: 628 LETKSKITHPVYSLYFPEEKQEWWWLYIADRKEQTLISMPYHVCTLKDTEEVELKFPAPG 687
LE + ++T PV + FP++++E WW+ I D K +LIS+ TL+ +V+L F AP
Sbjct: 1605 LEREEEVTGPVIAPLFPQKREEGWWVVIGDAKSNSLISIKR--LTLQQKAKVKLDFVAPA 1662
Query: 688 KPGNYQYTVFLRSDSYMGLDQIKPLKLEVHEAK 720
G + T++ SD+YMG DQ ++V EA+
Sbjct: 1663 TGGRHN-TLYFMSDAYMGCDQEYKFSVDVKEAE 1694
Score = 65.5 bits (158), Expect = 2e-10
Identities = 61/253 (24%), Positives = 124/253 (49%), Gaps = 32/253 (12%)
Query: 225 IRTTQIYTYFVYKTRNMDMKRLIMVLAGASEFDPQYNKDATSRPTDNILIPQLIREIGSI 284
I T I + + ++ LI +++ A+E++ + R ++ L+ QL +++
Sbjct: 1388 INYTTIELFSMSLNAKTKVRGLIEIISNAAEYE-----NIPIRHHEDNLLRQLAQKVPH- 1441
Query: 285 NLKKNEPPLTCPYSLKARVLLLSHLARMKIPETLEEDQQFMLKKCPALLQEMVNVICQLI 344
K N P P+ +K +LL +HL+RM++ L+ D + +L K L+Q V+V+
Sbjct: 1442 --KLNNPKFNDPH-VKTNLLLQAHLSRMQLSAELQSDTEEILSKAIRLIQACVDVL---- 1494
Query: 345 VMARNREEREFRAPTLASLENCMKLSQMAVQGLQQFKSPLLQLPHIEEDNLRRVSNHKKY 404
+ +P LA++E L+QM Q + S L +LP +R ++
Sbjct: 1495 ------SSNGWLSPALAAME----LAQMVTQAMWSEDSYLRRLPPFPSGLFKRCTDK--- 1541
Query: 405 KIKTIQDLVSLKESDRHTLLHFLEDEKYEEVMAVLGSFPYVTMDIKSQVLDDEDSNNITV 464
++++ D++ +++ +R+ LL L D + +V +P +++ +V+ D ++I
Sbjct: 1542 GVESVFDIMEMEDEERNALLQ-LTDSQIADVARFCNRYP--NIELSYEVV---DKDSIRS 1595
Query: 465 GSLVTVLVKLTRQ 477
G V VLV+L R+
Sbjct: 1596 GGPVVVLVQLERE 1608
>gi|194306642 DnaJ (Hsp40) homolog, subfamily B, member 12 [Homo
sapiens]
Length = 409
Score = 61.6 bits (148), Expect = 3e-09
Identities = 36/92 (39%), Positives = 53/92 (57%), Gaps = 4/92 (4%)
Query: 88 FLAYKVSKTDREYQEYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKG---GDEVMFMR 144
+ A +V+ R Q + YE+L + GA+ ++KK YR L+LK+HPDK G F
Sbjct: 128 YTAEQVAAVKRVKQCKDYYEILGVSRGASDEDLKKAYRRLALKFHPDKNHAPGATEAFKA 187
Query: 145 IAKAYAALTDEESRKNWEEFGNPDGPQATSFG 176
I AYA L++ E RK +++FG+ D QA G
Sbjct: 188 IGTAYAVLSNPEKRKQYDQFGD-DKSQAARHG 218
>gi|194306640 DnaJ (Hsp40) homolog, subfamily B, member 12 [Homo
sapiens]
Length = 409
Score = 61.6 bits (148), Expect = 3e-09
Identities = 36/92 (39%), Positives = 53/92 (57%), Gaps = 4/92 (4%)
Query: 88 FLAYKVSKTDREYQEYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKG---GDEVMFMR 144
+ A +V+ R Q + YE+L + GA+ ++KK YR L+LK+HPDK G F
Sbjct: 128 YTAEQVAAVKRVKQCKDYYEILGVSRGASDEDLKKAYRRLALKFHPDKNHAPGATEAFKA 187
Query: 145 IAKAYAALTDEESRKNWEEFGNPDGPQATSFG 176
I AYA L++ E RK +++FG+ D QA G
Sbjct: 188 IGTAYAVLSNPEKRKQYDQFGD-DKSQAARHG 218
>gi|56687498 DnaJ (Hsp40) homolog, subfamily C, member 16 [Homo
sapiens]
Length = 782
Score = 61.2 bits (147), Expect = 3e-09
Identities = 28/68 (41%), Positives = 48/68 (70%), Gaps = 3/68 (4%)
Query: 102 EYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKG---GDEVMFMRIAKAYAALTDEESR 158
+++PY VL + A+ A+IKK Y+ L+ ++HPDK G E F++I+KAY L++EE R
Sbjct: 27 DFDPYRVLGVSRTASQADIKKAYKKLAREWHPDKNKDPGAEDKFIQISKAYEILSNEEKR 86
Query: 159 KNWEEFGN 166
N++++G+
Sbjct: 87 SNYDQYGD 94
>gi|239745928 PREDICTED: hypothetical protein XP_002343618 [Homo
sapiens]
Length = 299
Score = 59.3 bits (142), Expect = 1e-08
Identities = 42/158 (26%), Positives = 80/158 (50%), Gaps = 22/158 (13%)
Query: 287 KKNEPPLTCPYSLKARVLLLSHLARMKIPETLEEDQQFMLKKCPALLQEMVNVICQLIVM 346
K N P P+ +K +LL +HL+RM++ L+ D + +L K L+Q V+V+
Sbjct: 93 KLNNPKFNDPH-IKTNLLLQAHLSRMQLSAELQSDTEEILSKAVRLVQACVDVLSS---- 147
Query: 347 ARNREEREFRAPTLASLENCMKLSQMAVQGLQQFKSPLLQLPHIEEDNLRRVSNHKKYKI 406
L+S M+L+QM Q + S L QLPH ++++R ++ +
Sbjct: 148 ----------NGWLSSALAAMELAQMVTQAMWSKDSYLKQLPHFISEHIKRCTDK---GV 194
Query: 407 KTIQDLVSLKESDRHTLLHF----LEDEKYEEVMAVLG 440
K++ D++ +++ +R+T+L + D++ E V+G
Sbjct: 195 KSVFDIMEMEDEERNTILQLTDSQITDKREEGWWVVIG 232
Score = 54.3 bits (129), Expect = 4e-07
Identities = 28/76 (36%), Positives = 46/76 (60%), Gaps = 3/76 (3%)
Query: 645 EEKQEWWWLYIADRKEQTLISMPYHVCTLKDTEEVELKFPAPGKPGNYQYTVFLRSDSYM 704
++++E WW+ I D K +LIS+ + L+ +V+L F AP G + YT++ SD+YM
Sbjct: 221 DKREEGWWVVIGDTKSNSLISIKRLI--LQQKAKVKLDFVAPAT-GAHNYTLYFMSDAYM 277
Query: 705 GLDQIKPLKLEVHEAK 720
G DQ ++V EA+
Sbjct: 278 GCDQEYKFSMDVKEAE 293
>gi|112293277 DnaJ (Hsp40) homolog, subfamily C, member 8 [Homo
sapiens]
Length = 253
Score = 57.8 bits (138), Expect = 4e-08
Identities = 29/73 (39%), Positives = 42/73 (57%), Gaps = 5/73 (6%)
Query: 92 KVSKTDREYQEYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGDEV-----MFMRIA 146
++++ Y NP+EVL +DP T EIKK++R LS+ HPDK D+ F +
Sbjct: 45 RLTRPGSSYFNLNPFEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVD 104
Query: 147 KAYAALTDEESRK 159
KAY L D+E +K
Sbjct: 105 KAYKLLLDQEQKK 117
Score = 31.6 bits (70), Expect = 2.9
Identities = 21/103 (20%), Positives = 50/103 (48%), Gaps = 9/103 (8%)
Query: 527 KKKKPLKKKPTPVLLPQSKQQKQKQA----NGVVGNEAAVKEDEEEVSDKGSDSEEEETN 582
++KK LKK+ P ++ + + KQA + E +K E E + E +
Sbjct: 136 ERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKERE----AKEMHERKRQ 191
Query: 583 RDSQSEKDDGSDRDSDREQDEKQNKDDEAE-WQELQQSIQRKE 624
R+ + E + + R+ + +++ ++++D + W+ Q + + K+
Sbjct: 192 REEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKK 234
>gi|4504511 DnaJ (Hsp40) homolog, subfamily A, member 1 [Homo
sapiens]
Length = 397
Score = 57.4 bits (137), Expect = 5e-08
Identities = 29/66 (43%), Positives = 44/66 (66%), Gaps = 1/66 (1%)
Query: 101 QEYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGDE-VMFMRIAKAYAALTDEESRK 159
+E Y+VL + P AT E+KK YR L+LKYHPDK +E F +I++AY L+D + R+
Sbjct: 3 KETTYYDVLGVKPNATQEELKKAYRKLALKYHPDKNPNEGEKFKQISQAYEVLSDAKKRE 62
Query: 160 NWEEFG 165
+++ G
Sbjct: 63 LYDKGG 68
>gi|45504382 DnaJ (Hsp40) homolog, subfamily C, member 5 [Homo
sapiens]
Length = 198
Score = 57.0 bits (136), Expect = 6e-08
Identities = 33/75 (44%), Positives = 41/75 (54%), Gaps = 4/75 (5%)
Query: 106 YEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGDEV----MFMRIAKAYAALTDEESRKNW 161
Y VL LD AT +IKK YR L+LKYHPDK D F I A+A LTD R +
Sbjct: 17 YHVLGLDKNATSDDIKKSYRKLALKYHPDKNPDNPEAADKFKEINNAHAILTDATKRNIY 76
Query: 162 EEFGNPDGPQATSFG 176
+++G+ A FG
Sbjct: 77 DKYGSLGLYVAEQFG 91
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 56.6 bits (135), Expect = 8e-08
Identities = 40/162 (24%), Positives = 79/162 (48%), Gaps = 10/162 (6%)
Query: 471 LVKLTRQTMAEVFEKEQSICAAEEQPAEDGQGETNKNRTKGGWQQKSKGPKKTAKSKKKK 530
+V T+++ + +E + + ++ A + + K G + S P+KT+ + K K
Sbjct: 1254 VVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGK 1313
Query: 531 PLKKKPTPVLLPQSKQQKQKQANGVVGNEAAVKEDEEEVSDKGSDSEE--EETNRDSQSE 588
+ K S K+K+ G +G++ A E EEE+ KG + E +++N S+ E
Sbjct: 1314 AKRDKA-------SGDVKEKKGKGSLGSQGAKDEPEEELQ-KGMGTVEGGDQSNPKSKKE 1365
Query: 589 KDDGSDRDSDREQDEKQNKDDEAEWQELQQSIQRKERALLET 630
K R D+E+ EK+ K +A ++ + Q+K++ +T
Sbjct: 1366 KKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKT 1407
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 56.6 bits (135), Expect = 8e-08
Identities = 40/162 (24%), Positives = 79/162 (48%), Gaps = 10/162 (6%)
Query: 471 LVKLTRQTMAEVFEKEQSICAAEEQPAEDGQGETNKNRTKGGWQQKSKGPKKTAKSKKKK 530
+V T+++ + +E + + ++ A + + K G + S P+KT+ + K K
Sbjct: 1293 VVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGK 1352
Query: 531 PLKKKPTPVLLPQSKQQKQKQANGVVGNEAAVKEDEEEVSDKGSDSEE--EETNRDSQSE 588
+ K S K+K+ G +G++ A E EEE+ KG + E +++N S+ E
Sbjct: 1353 AKRDKA-------SGDVKEKKGKGSLGSQGAKDEPEEELQ-KGMGTVEGGDQSNPKSKKE 1404
Query: 589 KDDGSDRDSDREQDEKQNKDDEAEWQELQQSIQRKERALLET 630
K R D+E+ EK+ K +A ++ + Q+K++ +T
Sbjct: 1405 KKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKT 1446
Score = 32.0 bits (71), Expect = 2.2
Identities = 31/120 (25%), Positives = 49/120 (40%), Gaps = 23/120 (19%)
Query: 478 TMAEVFEKEQSI----CAAEEQPAEDGQGETNKNRTKGGWQQKSKGPKKTAKSKKKKPLK 533
T+ E+E S+ AA+ GQ +++ T + K + K P +
Sbjct: 168 TLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVK-----PAQ 222
Query: 534 KKPTPVLLPQSKQQKQKQANGVVGN--------------EAAVKEDEEEVSDKGSDSEEE 579
K + V +S +K A G VG+ A E+E E S++GS+SEEE
Sbjct: 223 VKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEE 282
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 56.6 bits (135), Expect = 8e-08
Identities = 40/162 (24%), Positives = 79/162 (48%), Gaps = 10/162 (6%)
Query: 471 LVKLTRQTMAEVFEKEQSICAAEEQPAEDGQGETNKNRTKGGWQQKSKGPKKTAKSKKKK 530
+V T+++ + +E + + ++ A + + K G + S P+KT+ + K K
Sbjct: 1330 VVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGK 1389
Query: 531 PLKKKPTPVLLPQSKQQKQKQANGVVGNEAAVKEDEEEVSDKGSDSEE--EETNRDSQSE 588
+ K S K+K+ G +G++ A E EEE+ KG + E +++N S+ E
Sbjct: 1390 AKRDKA-------SGDVKEKKGKGSLGSQGAKDEPEEELQ-KGMGTVEGGDQSNPKSKKE 1441
Query: 589 KDDGSDRDSDREQDEKQNKDDEAEWQELQQSIQRKERALLET 630
K R D+E+ EK+ K +A ++ + Q+K++ +T
Sbjct: 1442 KKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKT 1483
Score = 32.0 bits (71), Expect = 2.2
Identities = 31/120 (25%), Positives = 49/120 (40%), Gaps = 23/120 (19%)
Query: 478 TMAEVFEKEQSI----CAAEEQPAEDGQGETNKNRTKGGWQQKSKGPKKTAKSKKKKPLK 533
T+ E+E S+ AA+ GQ +++ T + K + K P +
Sbjct: 168 TLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVK-----PAQ 222
Query: 534 KKPTPVLLPQSKQQKQKQANGVVGN--------------EAAVKEDEEEVSDKGSDSEEE 579
K + V +S +K A G VG+ A E+E E S++GS+SEEE
Sbjct: 223 VKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEE 282
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 56.6 bits (135), Expect = 8e-08
Identities = 40/162 (24%), Positives = 79/162 (48%), Gaps = 10/162 (6%)
Query: 471 LVKLTRQTMAEVFEKEQSICAAEEQPAEDGQGETNKNRTKGGWQQKSKGPKKTAKSKKKK 530
+V T+++ + +E + + ++ A + + K G + S P+KT+ + K K
Sbjct: 1253 VVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGK 1312
Query: 531 PLKKKPTPVLLPQSKQQKQKQANGVVGNEAAVKEDEEEVSDKGSDSEE--EETNRDSQSE 588
+ K S K+K+ G +G++ A E EEE+ KG + E +++N S+ E
Sbjct: 1313 AKRDKA-------SGDVKEKKGKGSLGSQGAKDEPEEELQ-KGMGTVEGGDQSNPKSKKE 1364
Query: 589 KDDGSDRDSDREQDEKQNKDDEAEWQELQQSIQRKERALLET 630
K R D+E+ EK+ K +A ++ + Q+K++ +T
Sbjct: 1365 KKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKT 1406
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 56.6 bits (135), Expect = 8e-08
Identities = 40/162 (24%), Positives = 79/162 (48%), Gaps = 10/162 (6%)
Query: 471 LVKLTRQTMAEVFEKEQSICAAEEQPAEDGQGETNKNRTKGGWQQKSKGPKKTAKSKKKK 530
+V T+++ + +E + + ++ A + + K G + S P+KT+ + K K
Sbjct: 1292 VVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGK 1351
Query: 531 PLKKKPTPVLLPQSKQQKQKQANGVVGNEAAVKEDEEEVSDKGSDSEE--EETNRDSQSE 588
+ K S K+K+ G +G++ A E EEE+ KG + E +++N S+ E
Sbjct: 1352 AKRDKA-------SGDVKEKKGKGSLGSQGAKDEPEEELQ-KGMGTVEGGDQSNPKSKKE 1403
Query: 589 KDDGSDRDSDREQDEKQNKDDEAEWQELQQSIQRKERALLET 630
K R D+E+ EK+ K +A ++ + Q+K++ +T
Sbjct: 1404 KKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKT 1445
Score = 32.0 bits (71), Expect = 2.2
Identities = 31/120 (25%), Positives = 49/120 (40%), Gaps = 23/120 (19%)
Query: 478 TMAEVFEKEQSI----CAAEEQPAEDGQGETNKNRTKGGWQQKSKGPKKTAKSKKKKPLK 533
T+ E+E S+ AA+ GQ +++ T + K + K P +
Sbjct: 168 TLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVK-----PAQ 222
Query: 534 KKPTPVLLPQSKQQKQKQANGVVGN--------------EAAVKEDEEEVSDKGSDSEEE 579
K + V +S +K A G VG+ A E+E E S++GS+SEEE
Sbjct: 223 VKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEE 282
>gi|194328760 DnaJ (Hsp40) homolog, subfamily A, member 4 isoform 2
[Homo sapiens]
Length = 397
Score = 56.6 bits (135), Expect = 8e-08
Identities = 29/66 (43%), Positives = 42/66 (63%), Gaps = 1/66 (1%)
Query: 101 QEYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGDE-VMFMRIAKAYAALTDEESRK 159
+E Y++L + P A+ EIKK YR L+LKYHPDK DE F I++AY L+D + R
Sbjct: 3 KETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEGEKFKLISQAYEVLSDPKKRD 62
Query: 160 NWEEFG 165
+++ G
Sbjct: 63 VYDQGG 68
>gi|194328758 DnaJ (Hsp40) homolog, subfamily A, member 4 isoform 1
[Homo sapiens]
Length = 426
Score = 56.6 bits (135), Expect = 8e-08
Identities = 29/66 (43%), Positives = 42/66 (63%), Gaps = 1/66 (1%)
Query: 101 QEYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGDE-VMFMRIAKAYAALTDEESRK 159
+E Y++L + P A+ EIKK YR L+LKYHPDK DE F I++AY L+D + R
Sbjct: 32 KETQYYDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEGEKFKLISQAYEVLSDPKKRD 91
Query: 160 NWEEFG 165
+++ G
Sbjct: 92 VYDQGG 97
>gi|201862587 DnaJ (Hsp40) homolog, subfamily B, member 5 isoform 1
[Homo sapiens]
Length = 420
Score = 55.8 bits (133), Expect = 1e-07
Identities = 32/92 (34%), Positives = 50/92 (54%), Gaps = 6/92 (6%)
Query: 80 LAGWALFLFLAYKVSKTDR---EYQEYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKG 136
L W L F+ ++ +T + Y++L + GA EIKK YR ++LKYHPDK
Sbjct: 49 LRAWTLNGFVKFRNKETSAGPVAVMGKDYYKILGIPSGANEDEIKKAYRKMALKYHPDKN 108
Query: 137 GD---EVMFMRIAKAYAALTDEESRKNWEEFG 165
+ E F IA+AY L+D + R ++++G
Sbjct: 109 KEPNAEEKFKEIAEAYDVLSDPKKRGLYDQYG 140
>gi|201862518 DnaJ (Hsp40) homolog, subfamily B, member 5 isoform 2
[Homo sapiens]
Length = 382
Score = 55.8 bits (133), Expect = 1e-07
Identities = 32/92 (34%), Positives = 50/92 (54%), Gaps = 6/92 (6%)
Query: 80 LAGWALFLFLAYKVSKTDR---EYQEYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKG 136
L W L F+ ++ +T + Y++L + GA EIKK YR ++LKYHPDK
Sbjct: 11 LRAWTLNGFVKFRNKETSAGPVAVMGKDYYKILGIPSGANEDEIKKAYRKMALKYHPDKN 70
Query: 137 GD---EVMFMRIAKAYAALTDEESRKNWEEFG 165
+ E F IA+AY L+D + R ++++G
Sbjct: 71 KEPNAEEKFKEIAEAYDVLSDPKKRGLYDQYG 102
>gi|29126218 DnaJ (Hsp40) homolog, subfamily C, member 5 beta [Homo
sapiens]
Length = 199
Score = 55.8 bits (133), Expect = 1e-07
Identities = 32/75 (42%), Positives = 43/75 (57%), Gaps = 4/75 (5%)
Query: 106 YEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGDE----VMFMRIAKAYAALTDEESRKNW 161
YE+L L GA+ EIKK YR L+LK+HPDK D+ F I A+A LTD R +
Sbjct: 21 YEILGLHKGASNEEIKKTYRKLALKHHPDKNPDDPAATEKFKEINNAHAILTDISKRSIY 80
Query: 162 EEFGNPDGPQATSFG 176
+++G+ A FG
Sbjct: 81 DKYGSLGLYVAEQFG 95
>gi|56549115 DnaJ (Hsp40) homolog, subfamily B, member 5 isoform 3
[Homo sapiens]
Length = 348
Score = 55.1 bits (131), Expect = 2e-07
Identities = 27/63 (42%), Positives = 40/63 (63%), Gaps = 3/63 (4%)
Query: 106 YEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGD---EVMFMRIAKAYAALTDEESRKNWE 162
Y++L + GA EIKK YR ++LKYHPDK + E F IA+AY L+D + R ++
Sbjct: 6 YKILGIPSGANEDEIKKAYRKMALKYHPDKNKEPNAEEKFKEIAEAYDVLSDPKKRGLYD 65
Query: 163 EFG 165
++G
Sbjct: 66 QYG 68
>gi|76880486 activating signal cointegrator 1 complex subunit 3
isoform a [Homo sapiens]
Length = 2202
Score = 54.7 bits (130), Expect = 3e-07
Identities = 38/123 (30%), Positives = 59/123 (47%), Gaps = 3/123 (2%)
Query: 597 SDREQDEKQNKDDEAEWQELQQSIQRKERALLETKSKITHPVYSLYFPEEKQEWWWLYIA 656
+D+ D K K + LQ S+QR K K + FP+ K E W+L +
Sbjct: 2063 ADKRDDNKWIKLHADQEYVLQVSLQRVHFGF--HKGKPESCAVTPRFPKSKDEGWFLILG 2120
Query: 657 DRKEQTLISMPYHVCTLKDTEEVELKFPAPGKPGNYQYTVFLRSDSYMGLDQIKPLKLEV 716
+ ++ LI++ V +++ L F P PG Y YT++ SD Y+GLDQ + L V
Sbjct: 2121 EVDKRELIALK-RVGYIRNHHVASLSFYTPEIPGRYIYTLYFMSDCYLGLDQQYDIYLNV 2179
Query: 717 HEA 719
+A
Sbjct: 2180 TQA 2182
Score = 38.1 bits (87), Expect = 0.031
Identities = 51/241 (21%), Positives = 96/241 (39%), Gaps = 39/241 (16%)
Query: 244 KRLIMVLAGASEFDPQYNKDATSRPTDNILIPQLIREIGSINLKKNEPPLTCPYSLKARV 303
+ L+ +L+ A E+ D R ++ + +L + + ++ N P++ KA +
Sbjct: 1843 EELLSILSDAEEYT-----DLPVRHNEDHMNSELAK---CLPIESNPHSFDSPHT-KAHL 1893
Query: 304 LLLSHLARMKIPETLEEDQQFMLKKCPALLQEMVNVICQLIVMARNREEREFRAPTLASL 363
LL +HL+R +P CP + V+ Q + + + + L ++
Sbjct: 1894 LLQAHLSRAMLP-------------CPDYDTDTKTVLDQALRVCQAMLDVAANQGWLVTV 1940
Query: 364 ENCMKLSQMAVQGLQQFKSPLLQLPHIEEDNLRRVSNHK----------KYKIKTIQDLV 413
N L QM +QG S LL LP+IE +L K + I+++ +L+
Sbjct: 1941 LNITNLIQMVIQGRWLKDSSLLTLPNIENHHLHLFKKWKPIMKGPHARGRTSIESLPELI 2000
Query: 414 SLKESDRHTLLHFLEDE----KYEEVMAVLGSFPYVTMDIKSQVLDD---EDSNNITVGS 466
H +E E K ++ L P + + I + D E N ++V +
Sbjct: 2001 HACGGKDHVFSSMVESELHAAKTKQAWNFLSHLPVINVGISVKGSWDDLVEGHNELSVST 2060
Query: 467 L 467
L
Sbjct: 2061 L 2061
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 54.7 bits (130), Expect = 3e-07
Identities = 62/299 (20%), Positives = 122/299 (40%), Gaps = 28/299 (9%)
Query: 473 KLTRQTMAEVFEKEQSICAAEEQPAEDGQGETNKNRTKGGWQQKSKGPKKTAKSKKKKPL 532
K +T+ + + A E+ AE + N +G ++K K KK K +K+K
Sbjct: 275 KFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDN--EGDKKKKDKKKKKGEKEEKEKEK 332
Query: 533 KKKPTPVLLPQSKQQKQKQANGVVGNEAAVKEDEEEVSDKGSDSEEEETNRDSQSEKDDG 592
KK P+ + ++ K E K +EEE + + E + + ++
Sbjct: 333 KKGPSKATVKAMQEALAKLKE----EEERQKREEEERIKRLEELEAKRKEEERLEQEKRE 388
Query: 593 SDRDSDREQDEKQNKDDEAEWQELQQSIQRKERAL-------LETKSKITHPVYSLYFPE 645
+ ++E+ E+ K+ + + +++ R E L +E SK + P + +
Sbjct: 389 RKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYED 448
Query: 646 EKQEWWWLYIADRKEQTLISMPYHVCTLKDTEEVEL----KFPAPGKPGNYQYTVFLRSD 701
+K++ I + E +S +C + E + + P P +P + T
Sbjct: 449 KKRK----KIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDT------ 498
Query: 702 SYMGLDQIKPLKLEVHEAKPVPENHPQWDTAIEGDEDQEDSEGFEDSFEEEEEEEEDDD 760
GLD + + + E + V N + +E++E+ E E+ E EEEEEE+ +
Sbjct: 499 EDAGLDDWEAMASD-EETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGE 556
Score = 37.7 bits (86), Expect = 0.040
Identities = 35/181 (19%), Positives = 74/181 (40%), Gaps = 28/181 (15%)
Query: 473 KLTRQTMAEVFEKEQSICAAEE-------------QPAEDGQGETNKNRTKGGWQQKSKG 519
K+ +Q ++ + +CAA E P E + E ++ W+ +
Sbjct: 453 KIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASD 512
Query: 520 PKKTAKSKKKKPLKKKPTPVLLPQSKQQKQKQANGVVGNEAAVKEDEEEVSDKGSDSEEE 579
+ K ++ K P + ++++++ +E + +E+EEE +GS+ +EE
Sbjct: 513 EETEKVEGNKVHIEVKENPEEEEEEEEEEEE-------DEESEEEEEEEGESEGSEGDEE 565
Query: 580 ETNRDSQSEKDDGSDRD----SDREQDEKQNKDDEAEWQE--LQQSIQRKERALLETKSK 633
+ EKD G D + D + + DD+ +E ++ +R E+ LE
Sbjct: 566 D--EKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKN 623
Query: 634 I 634
+
Sbjct: 624 V 624
Score = 36.2 bits (82), Expect = 0.12
Identities = 28/100 (28%), Positives = 52/100 (52%), Gaps = 15/100 (15%)
Query: 515 QKSKGPKKTAKSKKKKPLKKKPTPVLLPQSKQQKQKQANGVVGNEAAVKEDEEEVSDKGS 574
QKSKG KK K KKK+ + + + ++ +A G+ K D E V+ K +
Sbjct: 38 QKSKGKKK--KEKKKQDFDEDD----ILKELEELSLEAQGI-------KADRETVAVKPT 84
Query: 575 DSEEEE-TNRDSQSEKDDGSDRD-SDREQDEKQNKDDEAE 612
++ EEE T++D + + G + D + +E ++KD +++
Sbjct: 85 ENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSK 124
Score = 35.8 bits (81), Expect = 0.15
Identities = 67/330 (20%), Positives = 132/330 (40%), Gaps = 49/330 (14%)
Query: 472 VKLTRQTMAEVFEKEQSICAAEEQPAEDGQGETNKNRTKGGWQQKSKGPKKTAKSKKK-- 529
+K Q AE E+E+ + ++ + + K + K + K K +S++K
Sbjct: 225 IKTVAQKKAEKKERER-------KKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFE 277
Query: 530 -KPLKKKPT--PVLLPQSKQQKQKQANGVVGNEAAVKEDEEEVSDKGSDSEEEETNRDSQ 586
+ +K K T ++P S+++ + NE K+ +++ KG E+E+ +
Sbjct: 278 EETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKK-KKKGEKEEKEKEKKKGP 336
Query: 587 SEKDDGSDRDS---DREQDEKQNKDDEAEWQELQQ-SIQRKERALLETKSKITHPVYSLY 642
S+ + +++ +E++E+Q +++E + L++ +RKE LE + +
Sbjct: 337 SKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKE 396
Query: 643 FPEEKQEWWWLYIADRKEQTLISMPYHVCTLKDTEEVELKFPAPGKPGNYQYTVFLRSDS 702
E ++ L ++E + EV K P K Y+ +
Sbjct: 397 RKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQ 456
Query: 703 YMGLDQI-KPLKL------------EVHEAKPVPENHPQWDT---------AIEGDEDQE 740
+ ++ + ++L E E P E + DT A+ DE+ E
Sbjct: 457 QLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETE 516
Query: 741 DSEGF----------EDSFEEEEEEEEDDD 760
EG E+ EEEEEEEED++
Sbjct: 517 KVEGNKVHIEVKENPEEEEEEEEEEEEDEE 546
Score = 33.9 bits (76), Expect = 0.58
Identities = 54/250 (21%), Positives = 100/250 (40%), Gaps = 27/250 (10%)
Query: 406 IKTIQDLVSLKESDRHTLLHFLEDEKYEEVMAVLGSFPYVTMDIKSQVLDDEDSNNITVG 465
IK ++ V++K ++ + +D+K + SF D S+ L+D+DS +
Sbjct: 72 IKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFD----DNDSEELEDKDSKS---- 123
Query: 466 SLVTVLVKLTRQTMAEVFEKEQSICAAEEQPAEDGQGETNKNRTKGGWQQKSKGPKKTAK 525
K T + E++ + P + +G+ K+ K W + + K
Sbjct: 124 -------KKTAKPKVEMYSGSDDDDDFNKLPKK-AKGKAQKSNKK--WDGSEEDEDNSKK 173
Query: 526 SKKKKPLKKK-----PTPVLLPQSKQQKQKQANGVVGNEAAVKEDEEEVSDKGSDSEEEE 580
K++ + + L K QK+ Q N N + ED++ S K +++
Sbjct: 174 IKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDD-ASFKIKTVAQKK 232
Query: 581 TNRDSQSEKDDGSDRDSDREQDEKQNKDDEAEWQELQQSIQRKERALLET-KSKITHPVY 639
+ + K ++ R+ EK+ + + Q Q+ QRK ET KSK+T
Sbjct: 233 AEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEE--ETVKSKVTVDTG 290
Query: 640 SLYFPEEKQE 649
+ EEK E
Sbjct: 291 VIPASEEKAE 300
Score = 33.9 bits (76), Expect = 0.58
Identities = 43/216 (19%), Positives = 83/216 (38%), Gaps = 61/216 (28%)
Query: 463 TVGSLVTVLVKLTRQTMAEVFEKEQSICAAEEQPAEDGQGETNKNRTKGGWQQKSKGPKK 522
TV ++ L KL + + E+E+ I EE A+ + E + + +QK K K+
Sbjct: 340 TVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKE 399
Query: 523 TAKSK------------------------------------KKKPLKKKPTPVLLPQSKQ 546
K + KK+P+ + +PQ +
Sbjct: 400 RLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLE 459
Query: 547 QKQKQAN------------GVVGNE----AAVKEDEEEVSDKGSDSEEEETNRDSQSEKD 590
K+ + GV E E+EE+ D G D E + D ++EK
Sbjct: 460 SKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMAS-DEETEKV 518
Query: 591 DGS--------DRDSDREQDEKQNKDDEAEWQELQQ 618
+G+ + + + E++E++ +D+E+E +E ++
Sbjct: 519 EGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEE 554
Score = 33.5 bits (75), Expect = 0.75
Identities = 36/158 (22%), Positives = 71/158 (44%), Gaps = 18/158 (11%)
Query: 491 AAEEQPAEDGQGETNKNRTKGGWQQKSKGPKKTAKSKKKKPLKK-KPTPVLLPQSKQQ-- 547
AA+EQ + +G+ K + K + + + S + + +K + T + P +
Sbjct: 31 AAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEE 90
Query: 548 ---KQKQANGVVGNEAAVKE-DEEEVSDKGSDSEEEETNRDSQSEKDDGSDRDSD----- 598
K K+ G G + + + D EE+ DK DS+ ++T + + E GSD D D
Sbjct: 91 FTSKDKKKKGQKGKKQSFDDNDSEELEDK--DSKSKKTAKP-KVEMYSGSDDDDDFNKLP 147
Query: 599 ---REQDEKQNKDDEAEWQELQQSIQRKERALLETKSK 633
+ + +K NK + ++ S + KER+ + + +
Sbjct: 148 KKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGE 185
Score = 30.0 bits (66), Expect = 8.3
Identities = 22/88 (25%), Positives = 43/88 (48%), Gaps = 4/88 (4%)
Query: 447 MDIKSQVLDDEDSNNITVGSLVTVLVKLTRQTMAEVFEKEQSICAAEEQPAEDGQGETNK 506
+D + DE++ + G+ V + VK + E E+E+ +EE+ E+G+ E ++
Sbjct: 503 LDDWEAMASDEETEKVE-GNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSE 561
Query: 507 NRTKGGWQQKSKGPKKTAKSKKKKPLKK 534
+ +K K + K+ KKP K+
Sbjct: 562 GDEE---DEKVSDEKDSGKTLDKKPSKE 586
>gi|72534740 DnaJ (Hsp40) homolog, subfamily B, member 14 isoform 1
[Homo sapiens]
Length = 379
Score = 53.9 bits (128), Expect = 5e-07
Identities = 29/68 (42%), Positives = 40/68 (58%), Gaps = 3/68 (4%)
Query: 104 NPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKG---GDEVMFMRIAKAYAALTDEESRKN 160
N YEVL + A ++KK YR L+LK+HPDK G F +I AYA L++ E RK
Sbjct: 108 NYYEVLGVTKDAGDEDLKKAYRKLALKFHPDKNHAPGATDAFKKIGNAYAVLSNPEKRKQ 167
Query: 161 WEEFGNPD 168
++ GN +
Sbjct: 168 YDLTGNEE 175
>gi|205360840 DnaJ (Hsp40) homolog, subfamily A, member 3 isoform 2
[Homo sapiens]
Length = 453
Score = 53.1 bits (126), Expect = 9e-07
Identities = 32/103 (31%), Positives = 52/103 (50%), Gaps = 4/103 (3%)
Query: 68 PNIIPTVKKIVLLAGWALFLFLAYKVSKTDREYQEYNPYEVLNLDPGATVAEIKKQYRLL 127
P + T++ V L G F+ T + + Y++L + A+ EIKK Y L
Sbjct: 57 PRALLTLRPGVSLTGTKHNPFICTASFHTSAPLAKEDYYQILGVPRNASQKEIKKAYYQL 116
Query: 128 SLKYHPDKGGDE----VMFMRIAKAYAALTDEESRKNWEEFGN 166
+ KYHPD D+ F ++A+AY L+DE RK ++ +G+
Sbjct: 117 AKKYHPDTNKDDPKAKEKFSQLAEAYEVLSDEVKRKQYDAYGS 159
>gi|205360838 DnaJ (Hsp40) homolog, subfamily A, member 3 isoform 1
[Homo sapiens]
Length = 480
Score = 53.1 bits (126), Expect = 9e-07
Identities = 32/103 (31%), Positives = 52/103 (50%), Gaps = 4/103 (3%)
Query: 68 PNIIPTVKKIVLLAGWALFLFLAYKVSKTDREYQEYNPYEVLNLDPGATVAEIKKQYRLL 127
P + T++ V L G F+ T + + Y++L + A+ EIKK Y L
Sbjct: 57 PRALLTLRPGVSLTGTKHNPFICTASFHTSAPLAKEDYYQILGVPRNASQKEIKKAYYQL 116
Query: 128 SLKYHPDKGGDE----VMFMRIAKAYAALTDEESRKNWEEFGN 166
+ KYHPD D+ F ++A+AY L+DE RK ++ +G+
Sbjct: 117 AKKYHPDTNKDDPKAKEKFSQLAEAYEVLSDEVKRKQYDAYGS 159
>gi|5453690 DnaJ (Hsp40) homolog, subfamily B, member 1 [Homo
sapiens]
Length = 340
Score = 52.8 bits (125), Expect = 1e-06
Identities = 31/78 (39%), Positives = 42/78 (53%), Gaps = 7/78 (8%)
Query: 106 YEVLNLDPGATVAEIKKQYRLLSLKYHPDKG---GDEVMFMRIAKAYAALTDEESRKNWE 162
Y+ L L GA+ EIK+ YR +L+YHPDK G E F IA+AY L+D R+ ++
Sbjct: 6 YQTLGLARGASDEEIKRAYRRQALRYHPDKNKEPGAEEKFKEIAEAYDVLSDPRKREIFD 65
Query: 163 EFGNP----DGPQATSFG 176
+G GP S G
Sbjct: 66 RYGEEGLKGSGPSGGSGG 83
>gi|18093112 ABT1-associated protein [Homo sapiens]
Length = 851
Score = 52.8 bits (125), Expect = 1e-06
Identities = 39/156 (25%), Positives = 75/156 (48%), Gaps = 7/156 (4%)
Query: 495 QPAEDGQGETNKNRTKGGWQQKSKGPKKTAKSKKKKPLKKKPTPVLLPQSKQQKQKQANG 554
Q D E + G + K P+ +++ + +++ + + +G
Sbjct: 174 QHTTDSSLEEKQRTLDSGTSEIVKSPRIECSKTRRE--MQSVVQLIMTRDSDGYENSTDG 231
Query: 555 VVGNEAAVKEDEEEVSDKGSD--SEEEETNRDSQSEKDDGSDRDSDREQDEKQNKDDEAE 612
+ ++ A++ED E VS+ GSD SE E T+ S DDGS+ D + ++DE++++D+++E
Sbjct: 232 EMCDKDALEEDSESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSE 291
Query: 613 WQELQQS--IQRKERALLETKSKITHPVYSLYFPEE 646
+ S + + +ET S+ L FPEE
Sbjct: 292 DDDKSDSGPDLARGKGNIETSSEDEDDTADL-FPEE 326
Score = 33.5 bits (75), Expect = 0.75
Identities = 17/54 (31%), Positives = 32/54 (59%), Gaps = 2/54 (3%)
Query: 574 SDSEEEETNRDSQSEKDDGSDRDSDREQDEKQNKDDE--AEWQELQQSIQRKER 625
+ S E+E + + + DDG + + D + + Q D+E A++++L Q IQ KE+
Sbjct: 541 ASSSEDEEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEK 594
Score = 31.2 bits (69), Expect = 3.7
Identities = 14/28 (50%), Positives = 20/28 (71%), Gaps = 2/28 (7%)
Query: 735 GDED--QEDSEGFEDSFEEEEEEEEDDD 760
GD+D ++D E ED E+E+E+ EDDD
Sbjct: 267 GDDDGSEDDEEEDEDEEEDEDEDSEDDD 294
>gi|22749377 DnaJ (Hsp40) homolog, subfamily C, member 18 [Homo
sapiens]
Length = 358
Score = 52.0 bits (123), Expect = 2e-06
Identities = 26/66 (39%), Positives = 40/66 (60%), Gaps = 3/66 (4%)
Query: 104 NPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKG---GDEVMFMRIAKAYAALTDEESRKN 160
N YE+L + A+ E+KK YR L+LK+HPDK G F I A+A L++ + R
Sbjct: 82 NYYEILGVSRDASDEELKKAYRKLALKFHPDKNCAPGATDAFKAIGNAFAVLSNPDKRLR 141
Query: 161 WEEFGN 166
++E+G+
Sbjct: 142 YDEYGD 147
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,163,811
Number of Sequences: 37866
Number of extensions: 1486488
Number of successful extensions: 25505
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 470
Number of HSP's successfully gapped in prelim test: 611
Number of HSP's that attempted gapping in prelim test: 10672
Number of HSP's gapped (non-prelim): 9190
length of query: 760
length of database: 18,247,518
effective HSP length: 110
effective length of query: 650
effective length of database: 14,082,258
effective search space: 9153467700
effective search space used: 9153467700
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.