BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|5901956 follistatin-like 1 precursor [Homo sapiens] (308 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|5901956 follistatin-like 1 precursor [Homo sapiens] 650 0.0 gi|190358524 follistatin-like 5 isoform c [Homo sapiens] 89 4e-18 gi|190358522 follistatin-like 5 isoform b [Homo sapiens] 89 4e-18 gi|190358520 follistatin-like 5 isoform a [Homo sapiens] 89 4e-18 gi|54792136 follistatin-like 4 [Homo sapiens] 89 5e-18 gi|5453652 follistatin isoform FST317 precursor [Homo sapiens] 74 2e-13 gi|7242222 follistatin isoform FST344 precursor [Homo sapiens] 74 2e-13 gi|54873613 agrin [Homo sapiens] 62 8e-10 gi|5031701 follistatin-like 3 glycoprotein precursor [Homo sapiens] 55 8e-08 gi|190194423 SPARC-like 1 [Homo sapiens] 50 3e-06 gi|190341024 SPARC-like 1 [Homo sapiens] 50 3e-06 gi|29568105 transmembrane protein with EGF-like and two follista... 50 3e-06 gi|12383051 transmembrane protein with EGF-like and two follista... 49 6e-06 gi|93141003 testican 3 isoform 1 [Homo sapiens] 49 7e-06 gi|93141001 testican 3 isoform 2 [Homo sapiens] 49 7e-06 gi|116284392 mucin 2 precursor [Homo sapiens] 48 1e-05 gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] 48 1e-05 gi|7662036 sparc/osteonectin, cwcv and kazal-like domains proteo... 47 2e-05 gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and n... 47 2e-05 gi|28212222 WFIKKN2 protein [Homo sapiens] 46 4e-05 gi|4507171 secreted protein, acidic, cysteine-rich [Homo sapiens] 44 1e-04 gi|189163504 serine peptidase inhibitor, Kazal type 5 isoform c ... 43 4e-04 gi|74027261 serine peptidase inhibitor, Kazal type 5 isoform b p... 43 4e-04 gi|189163501 serine peptidase inhibitor, Kazal type 5 isoform a ... 43 4e-04 gi|134031945 SCO-spondin [Homo sapiens] 41 0.001 gi|4759164 sparc/osteonectin, cwcv and kazal-like domains proteo... 40 0.002 gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ... 40 0.002 gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ... 40 0.002 gi|161019170 mucin 5AC [Homo sapiens] 40 0.003 gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens] 40 0.003 >gi|5901956 follistatin-like 1 precursor [Homo sapiens] Length = 308 Score = 650 bits (1677), Expect = 0.0 Identities = 308/308 (100%), Positives = 308/308 (100%) Query: 1 MWKRWLALALALVAVAWVRAEEELRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQCKP 60 MWKRWLALALALVAVAWVRAEEELRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQCKP Sbjct: 1 MWKRWLALALALVAVAWVRAEEELRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQCKP 60 Query: 61 HKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKEKKSVSPSASPVVCYQSNRDE 120 HKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKEKKSVSPSASPVVCYQSNRDE Sbjct: 61 HKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKEKKSVSPSASPVVCYQSNRDE 120 Query: 121 LRRRIIQWLEAEIIPDGWFSKGSNYSEILDKYFKNFDNGDSRLDSSEFLKFVEQNETAIN 180 LRRRIIQWLEAEIIPDGWFSKGSNYSEILDKYFKNFDNGDSRLDSSEFLKFVEQNETAIN Sbjct: 121 LRRRIIQWLEAEIIPDGWFSKGSNYSEILDKYFKNFDNGDSRLDSSEFLKFVEQNETAIN 180 Query: 181 ITTYPDQENNKLLRGLCVDALIELSDENADWKLSFQEFLKCLNPSFNPPEKKCALEDETY 240 ITTYPDQENNKLLRGLCVDALIELSDENADWKLSFQEFLKCLNPSFNPPEKKCALEDETY Sbjct: 181 ITTYPDQENNKLLRGLCVDALIELSDENADWKLSFQEFLKCLNPSFNPPEKKCALEDETY 240 Query: 241 ADGAETEVDCNRCVCACGNWVCTAMTCDGKNQKGAQTQTEEEMTRYVQELQKHQETAEKT 300 ADGAETEVDCNRCVCACGNWVCTAMTCDGKNQKGAQTQTEEEMTRYVQELQKHQETAEKT Sbjct: 241 ADGAETEVDCNRCVCACGNWVCTAMTCDGKNQKGAQTQTEEEMTRYVQELQKHQETAEKT 300 Query: 301 KRVSTKEI 308 KRVSTKEI Sbjct: 301 KRVSTKEI 308 >gi|190358524 follistatin-like 5 isoform c [Homo sapiens] Length = 837 Score = 89.4 bits (220), Expect = 4e-18 Identities = 57/196 (29%), Positives = 96/196 (48%), Gaps = 26/196 (13%) Query: 31 CANVFCGAGRECAVT-EKGEPTCLCIEQCKPHKRPVCGSNGKTYLNHCELHRDACLTGSK 89 C N +CG GR C + E G+ C C++ CK H +PVCGS+G+ Y NHCE+HR ACL K Sbjct: 64 CENKYCGLGRHCVTSRETGQAECACMDLCKRHYKPVCGSDGEFYENHCEVHRAACLKKQK 123 Query: 90 IQVDYDGHCKEKKSVSPSASPVVCYQSNRDELRRRIIQWLEAE-IIPDGWFSKGSNYSE- 147 I + ++ C K C + +++ ++ + I+ + G + S Sbjct: 124 ITIVHNEDCFFKGD--------KCKTTEYSKMKNMLLDLQNQKYIMQENENPNGDDISRK 175 Query: 148 --ILDKYFKNFD-NGDSRLDSSEFLKFVEQNETAINITTYPDQENNKLLRGLCVDALIEL 204 ++D+ FK FD + + +D +E + ++Q +E K L + L++ Sbjct: 176 KLLVDQMFKYFDADSNGLVDINELTQVIKQ------------EELGKDLFDCTLYVLLKY 223 Query: 205 SDENADWKLSFQEFLK 220 D NAD L+ +EF + Sbjct: 224 DDFNADKHLALEEFYR 239 >gi|190358522 follistatin-like 5 isoform b [Homo sapiens] Length = 846 Score = 89.4 bits (220), Expect = 4e-18 Identities = 57/196 (29%), Positives = 96/196 (48%), Gaps = 26/196 (13%) Query: 31 CANVFCGAGRECAVT-EKGEPTCLCIEQCKPHKRPVCGSNGKTYLNHCELHRDACLTGSK 89 C N +CG GR C + E G+ C C++ CK H +PVCGS+G+ Y NHCE+HR ACL K Sbjct: 64 CENKYCGLGRHCVTSRETGQAECACMDLCKRHYKPVCGSDGEFYENHCEVHRAACLKKQK 123 Query: 90 IQVDYDGHCKEKKSVSPSASPVVCYQSNRDELRRRIIQWLEAE-IIPDGWFSKGSNYSE- 147 I + ++ C K C + +++ ++ + I+ + G + S Sbjct: 124 ITIVHNEDCFFKGD--------KCKTTEYSKMKNMLLDLQNQKYIMQENENPNGDDISRK 175 Query: 148 --ILDKYFKNFD-NGDSRLDSSEFLKFVEQNETAINITTYPDQENNKLLRGLCVDALIEL 204 ++D+ FK FD + + +D +E + ++Q +E K L + L++ Sbjct: 176 KLLVDQMFKYFDADSNGLVDINELTQVIKQ------------EELGKDLFDCTLYVLLKY 223 Query: 205 SDENADWKLSFQEFLK 220 D NAD L+ +EF + Sbjct: 224 DDFNADKHLALEEFYR 239 >gi|190358520 follistatin-like 5 isoform a [Homo sapiens] Length = 847 Score = 89.4 bits (220), Expect = 4e-18 Identities = 57/196 (29%), Positives = 96/196 (48%), Gaps = 26/196 (13%) Query: 31 CANVFCGAGRECAVT-EKGEPTCLCIEQCKPHKRPVCGSNGKTYLNHCELHRDACLTGSK 89 C N +CG GR C + E G+ C C++ CK H +PVCGS+G+ Y NHCE+HR ACL K Sbjct: 65 CENKYCGLGRHCVTSRETGQAECACMDLCKRHYKPVCGSDGEFYENHCEVHRAACLKKQK 124 Query: 90 IQVDYDGHCKEKKSVSPSASPVVCYQSNRDELRRRIIQWLEAE-IIPDGWFSKGSNYSE- 147 I + ++ C K C + +++ ++ + I+ + G + S Sbjct: 125 ITIVHNEDCFFKGD--------KCKTTEYSKMKNMLLDLQNQKYIMQENENPNGDDISRK 176 Query: 148 --ILDKYFKNFD-NGDSRLDSSEFLKFVEQNETAINITTYPDQENNKLLRGLCVDALIEL 204 ++D+ FK FD + + +D +E + ++Q +E K L + L++ Sbjct: 177 KLLVDQMFKYFDADSNGLVDINELTQVIKQ------------EELGKDLFDCTLYVLLKY 224 Query: 205 SDENADWKLSFQEFLK 220 D NAD L+ +EF + Sbjct: 225 DDFNADKHLALEEFYR 240 >gi|54792136 follistatin-like 4 [Homo sapiens] Length = 842 Score = 89.0 bits (219), Expect = 5e-18 Identities = 63/210 (30%), Positives = 97/210 (46%), Gaps = 29/210 (13%) Query: 18 VRAEEELRSKSKI---CANVFCGAGRECAVTEK-GEPTCLCIEQCKPHKRPVCGSNGKTY 73 V E L S +++ C FC G C ++ K GEP C C+E C+P PVCGS+G+ Y Sbjct: 49 VTRREGLSSHNELLASCGKKFCSRGSRCVLSRKTGEPECQCLEACRPSYVPVCGSDGRFY 108 Query: 74 LNHCELHRDACLTGSKIQVDYDGHCKEKKSVSPSASPVVCYQSNRDELRRRIIQWLEAEI 133 NHC+LHR ACL G +I V + C K C + L + ++ L+ + Sbjct: 109 ENHCKLHRAACLLGKRITVIHSKDCFLKGD--------TCTMAGYARL-KNVLLALQTRL 159 Query: 134 IP----DGWFSKGSNYSEILDKYFKNFD-NGDSRLDSSEFLKFVEQNETAINITTYPDQE 188 P D S +++ F++ D +G+ L SSE + V + Q+ Sbjct: 160 QPLQEGDSRQDPASQKRLLVESLFRDLDADGNGHLSSSELAQHVLKK-----------QD 208 Query: 189 NNKLLRGLCVDALIELSDENADWKLSFQEF 218 ++ L G L+ D N+D L+ +EF Sbjct: 209 LDEDLLGCSPGDLLRFDDYNSDSSLTLREF 238 >gi|5453652 follistatin isoform FST317 precursor [Homo sapiens] Length = 317 Score = 73.6 bits (179), Expect = 2e-13 Identities = 35/91 (38%), Positives = 50/91 (54%), Gaps = 4/91 (4%) Query: 31 CANVFCGAGRECAVTEKGEPTCLCIEQCK--PHKRPVCGSNGKTYLNHCELHRDACLTGS 88 C NV CG G++C + +K +P C+C C K PVCG +GKTY N C L + C Sbjct: 95 CENVDCGPGKKCRMNKKNKPRCVCAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQP 154 Query: 89 KIQVDYDGHCKE--KKSVSPSASPVVCYQSN 117 +++V Y G CK+ + P +S V Q+N Sbjct: 155 ELEVQYQGRCKKTCRDVFCPGSSTCVVDQTN 185 Score = 52.8 bits (125), Expect = 4e-07 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 4/79 (5%) Query: 29 KICANVFCGAGRECAVTEKGEPTCLCIEQCKPH----KRPVCGSNGKTYLNHCELHRDAC 84 K C +VFC C V + C+ + P ++ +CG++G TY + C L + C Sbjct: 166 KTCRDVFCPGSSTCVVDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATC 225 Query: 85 LTGSKIQVDYDGHCKEKKS 103 L G I + Y+G C + KS Sbjct: 226 LLGRSIGLAYEGKCIKAKS 244 Score = 50.4 bits (119), Expect = 2e-06 Identities = 27/76 (35%), Positives = 39/76 (51%), Gaps = 4/76 (5%) Query: 27 KSKICANVFCGAGRECAVTEK-GEPTC-LCIEQCKPHK--RPVCGSNGKTYLNHCELHRD 82 K+K C ++ C G++C K G C LC E C K PVC S+ TY + C + Sbjct: 241 KAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASDNATYASECAMKEA 300 Query: 83 ACLTGSKIQVDYDGHC 98 AC +G ++V + G C Sbjct: 301 ACSSGVLLEVKHSGSC 316 >gi|7242222 follistatin isoform FST344 precursor [Homo sapiens] Length = 344 Score = 73.6 bits (179), Expect = 2e-13 Identities = 35/91 (38%), Positives = 50/91 (54%), Gaps = 4/91 (4%) Query: 31 CANVFCGAGRECAVTEKGEPTCLCIEQCK--PHKRPVCGSNGKTYLNHCELHRDACLTGS 88 C NV CG G++C + +K +P C+C C K PVCG +GKTY N C L + C Sbjct: 95 CENVDCGPGKKCRMNKKNKPRCVCAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQP 154 Query: 89 KIQVDYDGHCKE--KKSVSPSASPVVCYQSN 117 +++V Y G CK+ + P +S V Q+N Sbjct: 155 ELEVQYQGRCKKTCRDVFCPGSSTCVVDQTN 185 Score = 52.8 bits (125), Expect = 4e-07 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 4/79 (5%) Query: 29 KICANVFCGAGRECAVTEKGEPTCLCIEQCKPH----KRPVCGSNGKTYLNHCELHRDAC 84 K C +VFC C V + C+ + P ++ +CG++G TY + C L + C Sbjct: 166 KTCRDVFCPGSSTCVVDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATC 225 Query: 85 LTGSKIQVDYDGHCKEKKS 103 L G I + Y+G C + KS Sbjct: 226 LLGRSIGLAYEGKCIKAKS 244 Score = 50.4 bits (119), Expect = 2e-06 Identities = 27/76 (35%), Positives = 39/76 (51%), Gaps = 4/76 (5%) Query: 27 KSKICANVFCGAGRECAVTEK-GEPTC-LCIEQCKPHK--RPVCGSNGKTYLNHCELHRD 82 K+K C ++ C G++C K G C LC E C K PVC S+ TY + C + Sbjct: 241 KAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASDNATYASECAMKEA 300 Query: 83 ACLTGSKIQVDYDGHC 98 AC +G ++V + G C Sbjct: 301 ACSSGVLLEVKHSGSC 316 >gi|54873613 agrin [Homo sapiens] Length = 2045 Score = 61.6 bits (148), Expect = 8e-10 Identities = 30/68 (44%), Positives = 37/68 (54%), Gaps = 1/68 (1%) Query: 31 CANVFCGAGRECAVTEKGEPTCLCIEQCKPHKRPVCGSNGKTYLNHCELHRDACLTGSKI 90 C V C G CAV + G+ C C++ C PVCGS+G TY + CEL AC G +I Sbjct: 468 CLGVQCAFGATCAV-KNGQAACECLQACSSLYDPVCGSDGVTYGSACELEATACTLGREI 526 Query: 91 QVDYDGHC 98 QV G C Sbjct: 527 QVARKGPC 534 Score = 53.1 bits (126), Expect = 3e-07 Identities = 32/82 (39%), Positives = 41/82 (50%), Gaps = 5/82 (6%) Query: 31 CANVFCGAGRECAVTEKGEPTCLCIEQCKPHKRP--VCGSNGKTYLNHCELHRDACLTGS 88 CA + C G C V E G C+C P VCGS+G TY N C+L AC G Sbjct: 901 CAEMRCEFGARC-VEESGSAHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTIACRQGL 959 Query: 89 KIQVDYDGHCKEKKSVSPSASP 110 +I + G C+E +V+PS P Sbjct: 960 QISIQSLGPCQE--AVAPSTHP 979 Score = 51.2 bits (121), Expect = 1e-06 Identities = 28/81 (34%), Positives = 38/81 (46%), Gaps = 2/81 (2%) Query: 31 CANVFCGAGRECAVTEKG-EPTCLCIEQCK-PHKRPVCGSNGKTYLNHCELHRDACLTGS 88 C+NV C G CA + G +CLC C+ + VCGS+G Y C+L R AC Sbjct: 248 CSNVTCSFGSTCARSADGLTASCLCPATCRGAPEGTVCGSDGADYPGECQLLRRACARQE 307 Query: 89 KIQVDYDGHCKEKKSVSPSAS 109 + +DG C + P S Sbjct: 308 NVFKKFDGPCDPCQGALPDPS 328 Score = 48.5 bits (114), Expect = 7e-06 Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 3/78 (3%) Query: 31 CANVFCGAGRECAVTEKG--EPTCLCIEQ-CKPHKRPVCGSNGKTYLNHCELHRDACLTG 87 C + CG G C +G +C+C + C PVCGS+ TY N CEL R C Sbjct: 172 CRGMLCGFGAVCEPNAEGPGRASCVCKKSPCPSVVAPVCGSDASTYSNECELQRAQCSQQ 231 Query: 88 SKIQVDYDGHCKEKKSVS 105 +I++ G C + S Sbjct: 232 RRIRLLSRGPCGSRDPCS 249 Score = 48.5 bits (114), Expect = 7e-06 Identities = 24/64 (37%), Positives = 32/64 (50%) Query: 36 CGAGRECAVTEKGEPTCLCIEQCKPHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYD 95 CG R A+ E C+C +C +PVCGS+G TY + C LH AC + V Sbjct: 537 CGQCRFGALCEAETGRCVCPSECVALAQPVCGSDGHTYPSECMLHVHACTHQISLHVASA 596 Query: 96 GHCK 99 G C+ Sbjct: 597 GPCE 600 Score = 47.4 bits (111), Expect = 2e-05 Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 5/70 (7%) Query: 31 CANVFCGAGRECAVTEKGEPTCLCIEQCKPHKRPVCGSNGKTYLNHCELHRDACLTGSKI 90 C + C G C+ + C+C P PVCGS+G TY + CEL ACL ++I Sbjct: 602 CGDAVCAFGAVCSAGQ-----CVCPRCEHPPPGPVCGSDGVTYGSACELREAACLQQTQI 656 Query: 91 QVDYDGHCKE 100 + G C++ Sbjct: 657 EEARAGPCEQ 666 Score = 39.3 bits (90), Expect = 0.004 Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 2/67 (2%) Query: 52 CLCIEQCKPHK-RPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKEKK-SVSPSAS 109 C+C C+ PVCGS+G TY CEL + C + + V G C+ + P + Sbjct: 703 CVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRGLYVAAQGACRGPTFAPLPPVA 762 Query: 110 PVVCYQS 116 P+ C Q+ Sbjct: 763 PLHCAQT 769 Score = 38.1 bits (87), Expect = 0.010 Identities = 20/71 (28%), Positives = 28/71 (39%), Gaps = 2/71 (2%) Query: 31 CANVFCGAGRECAVTEKGEPTCLCI--EQCKPHKRPVCGSNGKTYLNHCELHRDACLTGS 88 C R C V + + + E C + PVCG +G TY N C + R G Sbjct: 320 CQGALPDPSRSCRVNPRTRRPEMLLRPESCPARQAPVCGDDGVTYENDCVMGRSGAARGL 379 Query: 89 KIQVDYDGHCK 99 +Q G C+ Sbjct: 380 LLQKVRSGQCQ 390 Score = 36.2 bits (82), Expect = 0.038 Identities = 18/61 (29%), Positives = 27/61 (44%), Gaps = 1/61 (1%) Query: 44 VTEKGEPTCLCIE-QCKPHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKEKK 102 ++ +G P C C C RPVC +G+TY + C + C I + G C + Sbjct: 406 LSRRGRPRCSCDRVTCDGAYRPVCAQDGRTYDSDCWRQQAECRQQRAIPSKHQGPCDQAP 465 Query: 103 S 103 S Sbjct: 466 S 466 >gi|5031701 follistatin-like 3 glycoprotein precursor [Homo sapiens] Length = 263 Score = 55.1 bits (131), Expect = 8e-08 Identities = 31/85 (36%), Positives = 39/85 (45%), Gaps = 9/85 (10%) Query: 31 CANVFCGAGRECAVTEKGEPTCLCIEQCK--PHKRPVCGSNGKTYLNHCELHRDACLTGS 88 C V CG G+ C + G P C C C P + VCGS+G TY + CEL C Sbjct: 99 CDGVECGPGKACRMLG-GRPRCECAPDCSGLPARLQVCGSDGATYRDECELRAARCRGHP 157 Query: 89 KIQVDYDGHCKEKKSVSPSASPVVC 113 + V Y G C++ S VVC Sbjct: 158 DLSVMYRGRCRK------SCEHVVC 176 Score = 43.9 bits (102), Expect = 2e-04 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 5/75 (6%) Query: 29 KICANVFCGAGRECAVTEKGEPTCLCIEQ--CKPHKRP---VCGSNGKTYLNHCELHRDA 83 K C +V C + C V + G C+ C P +CG+N TY++ C + + Sbjct: 169 KSCEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPVPSSPGQELCGNNNVTYISSCHMRQAT 228 Query: 84 CLTGSKIQVDYDGHC 98 C G I V + G C Sbjct: 229 CFLGRSIGVRHAGSC 243 >gi|190194423 SPARC-like 1 [Homo sapiens] Length = 664 Score = 50.1 bits (118), Expect = 3e-06 Identities = 32/95 (33%), Positives = 47/95 (49%), Gaps = 16/95 (16%) Query: 21 EEELRSKSKI-------CANVFCGAGRECAVTEKGEPTCLCIE--QCKPHK--RPVCGSN 69 EEE S+ + C + C G C ++G+P C+C + C P K VCG++ Sbjct: 416 EEETSSEGNMRVHAVDSCMSFQCKRGHICKADQQGKPHCVCQDPVTCPPTKPLDQVCGTD 475 Query: 70 GKTYLNHCELHRDAC-LTGSK----IQVDYDGHCK 99 +TY + C L C L G+K +Q+DY G CK Sbjct: 476 NQTYASSCHLFATKCRLEGTKKGHQLQLDYFGACK 510 >gi|190341024 SPARC-like 1 [Homo sapiens] Length = 664 Score = 50.1 bits (118), Expect = 3e-06 Identities = 32/95 (33%), Positives = 47/95 (49%), Gaps = 16/95 (16%) Query: 21 EEELRSKSKI-------CANVFCGAGRECAVTEKGEPTCLCIE--QCKPHK--RPVCGSN 69 EEE S+ + C + C G C ++G+P C+C + C P K VCG++ Sbjct: 416 EEETSSEGNMRVHAVDSCMSFQCKRGHICKADQQGKPHCVCQDPVTCPPTKPLDQVCGTD 475 Query: 70 GKTYLNHCELHRDAC-LTGSK----IQVDYDGHCK 99 +TY + C L C L G+K +Q+DY G CK Sbjct: 476 NQTYASSCHLFATKCRLEGTKKGHQLQLDYFGACK 510 >gi|29568105 transmembrane protein with EGF-like and two follistatin-like domains 1 [Homo sapiens] Length = 380 Score = 50.1 bits (118), Expect = 3e-06 Identities = 29/73 (39%), Positives = 33/73 (45%), Gaps = 1/73 (1%) Query: 26 SKSKICANVFCGAGRECAVTEKGEPTCLCIEQCKPHKRPVCGSNGKTYLNHCELHRDACL 85 S ++C C G C G C C QC + PVCGSNG TY N C L R AC Sbjct: 72 SDVRVCDESSCKYGGVCKEDGDGLK-CACQFQCHTNYIPVCGSNGDTYQNECFLRRAACK 130 Query: 86 TGSKIQVDYDGHC 98 +I V G C Sbjct: 131 HQKEITVIARGPC 143 Score = 40.8 bits (94), Expect = 0.002 Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 1/55 (1%) Query: 52 CLCIEQCKPHK-RPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKEKKSVS 105 C+C C + PVC S+G +Y N C + +C+ +I + + GHC + S Sbjct: 188 CVCNIDCSGYSFNPVCASDGSSYNNPCFVREASCIKQEQIDIRHLGHCTDTDDTS 242 >gi|12383051 transmembrane protein with EGF-like and two follistatin-like domains 2 [Homo sapiens] Length = 374 Score = 48.9 bits (115), Expect = 6e-06 Identities = 22/48 (45%), Positives = 29/48 (60%) Query: 51 TCLCIEQCKPHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHC 98 TC+C +C PVCGSNG++Y N C L + AC S+I V +G C Sbjct: 88 TCVCQFKCNNDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSC 135 Score = 41.2 bits (95), Expect = 0.001 Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 2/71 (2%) Query: 36 CGAGRECAVTEKGEPTCLCIEQC-KPHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDY 94 C G EC + + C+C C + + P+C S+GK+Y N C++ +C KI+V Sbjct: 165 CQFGAECD-EDAEDVWCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMS 223 Query: 95 DGHCKEKKSVS 105 G C++ + + Sbjct: 224 LGRCQDNTTTT 234 >gi|93141003 testican 3 isoform 1 [Homo sapiens] Length = 433 Score = 48.5 bits (114), Expect = 7e-06 Identities = 29/86 (33%), Positives = 39/86 (45%), Gaps = 4/86 (4%) Query: 50 PTCLCIEQCKP-HKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKEKKSVSPSA 108 P +QC + PVCGS+G TY C+L AC+ G +I V +GHC S Sbjct: 131 PILSTCKQCPVVYPSPVCGSDGHTYSFQCKLEYQACVLGKQISVKCEGHCPCPSDKPTST 190 Query: 109 SPVV---CYQSNRDELRRRIIQWLEA 131 S V C E+ R+ W +A Sbjct: 191 SRNVKRACSDLEFREVANRLRDWFKA 216 >gi|93141001 testican 3 isoform 2 [Homo sapiens] Length = 436 Score = 48.5 bits (114), Expect = 7e-06 Identities = 29/86 (33%), Positives = 39/86 (45%), Gaps = 4/86 (4%) Query: 50 PTCLCIEQCKP-HKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKEKKSVSPSA 108 P +QC + PVCGS+G TY C+L AC+ G +I V +GHC S Sbjct: 134 PILSTCKQCPVVYPSPVCGSDGHTYSFQCKLEYQACVLGKQISVKCEGHCPCPSDKPTST 193 Query: 109 SPVV---CYQSNRDELRRRIIQWLEA 131 S V C E+ R+ W +A Sbjct: 194 SRNVKRACSDLEFREVANRLRDWFKA 219 >gi|116284392 mucin 2 precursor [Homo sapiens] Length = 5179 Score = 48.1 bits (113), Expect = 1e-05 Identities = 18/40 (45%), Positives = 23/40 (57%) Query: 230 EKKCALEDETYADGAETEVDCNRCVCACGNWVCTAMTCDG 269 E C ++ Y+ GA+ +VDCN C C G WVCT C G Sbjct: 819 ECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHG 858 Score = 42.7 bits (99), Expect = 4e-04 Identities = 16/37 (43%), Positives = 18/37 (48%) Query: 233 CALEDETYADGAETEVDCNRCVCACGNWVCTAMTCDG 269 C L Y G E DC +CVC G WVC + C G Sbjct: 353 CRLHGHLYTPGQEITNDCEQCVCNAGRWVCKDLPCPG 389 >gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] Length = 2639 Score = 48.1 bits (113), Expect = 1e-05 Identities = 18/40 (45%), Positives = 23/40 (57%) Query: 230 EKKCALEDETYADGAETEVDCNRCVCACGNWVCTAMTCDG 269 E C ++ Y+ GA+ +VDCN C C G WVCT C G Sbjct: 720 ECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHG 759 >gi|7662036 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 isoform 2 [Homo sapiens] Length = 424 Score = 47.4 bits (111), Expect = 2e-05 Identities = 56/241 (23%), Positives = 91/241 (37%), Gaps = 51/241 (21%) Query: 19 RAEEELRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQ--------------------- 57 + +E L + C V C + C +G +CI + Sbjct: 78 QGDEALDTTKDPCQKVKCSRHKVCIA--QGYQRAMCISRKKLEHRIKQPTVKLHGNKDSI 135 Query: 58 CKP----HKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHC----KEKKSVSPSAS 109 CKP VCGS+G TY + C+L + ACL+ ++ V +G C ++ + + Sbjct: 136 CKPCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPCPCPTEQAATSTADGK 195 Query: 110 PVVCYQSNRDELRRRIIQW---LEAEIIPDGWFSKGSNYSEILDKYFKNFDNGD-----S 161 P C + +L R+ W L +G S + + LDK S Sbjct: 196 PETCTGQDLADLGDRLRDWFQLLHENSKQNGSASSVAGPASGLDKSLGASCKDSIGWMFS 255 Query: 162 RLDSSEFLKFVEQNE-TAINITTYPDQENNKLLRGLCVDALIELSDENADWKLSFQEFLK 220 +LD+S L F++Q E AIN+ Y +C+ D D ++S E+ Sbjct: 256 KLDTSADL-FLDQTELAAINLDKYE----------VCIRPFFNSCDTYKDGRVSTAEWCF 304 Query: 221 C 221 C Sbjct: 305 C 305 >gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 precursor [Homo sapiens] Length = 548 Score = 47.0 bits (110), Expect = 2e-05 Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 4/70 (5%) Query: 39 GRECAVTEKGEPTCLCIEQCKPHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHC 98 G +C + + G+P C C ++C+ C S+G TY N C + +ACL G + + C Sbjct: 102 GSDCDIWD-GQPVCRCRDRCEKEPSFTCASDGLTYYNRCYMDAEACLRGLHLHI---VPC 157 Query: 99 KEKKSVSPSA 108 K S PS+ Sbjct: 158 KHVLSWPPSS 167 >gi|28212222 WFIKKN2 protein [Homo sapiens] Length = 576 Score = 46.2 bits (108), Expect = 4e-05 Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 2/67 (2%) Query: 27 KSKICANVFC-GAGRECAVTEKGEPTCLCIEQCKPHKRPVCGSNGKTYLNHCELHRDACL 85 K C + C G EC + + G+P C C ++C+ C S+G TY N C + +AC Sbjct: 107 KEATCDHFMCLQQGSECDIWD-GQPVCKCKDRCEKEPSFTCASDGLTYYNRCYMDAEACS 165 Query: 86 TGSKIQV 92 G + V Sbjct: 166 KGITLAV 172 >gi|4507171 secreted protein, acidic, cysteine-rich [Homo sapiens] Length = 303 Score = 44.3 bits (103), Expect = 1e-04 Identities = 32/124 (25%), Positives = 51/124 (41%), Gaps = 20/124 (16%) Query: 21 EEELRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQCK-----PHKRPVCGSNGKTYLN 75 EEE+ +++ C N C G+ C + E P C+C + VC ++ KT+ + Sbjct: 63 EEEVVAENP-CQNHHCKHGKVCELDENNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTFDS 121 Query: 76 HCELHRDACL-----TGSKIQVDYDGHCKEKKSVSPSASPVVCYQSNRDELRRRIIQWLE 130 C C G K+ +DY G C K + P C S E R+ WL+ Sbjct: 122 SCHFFATKCTLEGTKKGHKLHLDYIGPC---KYIPP------CLDSELTEFPLRMRDWLK 172 Query: 131 AEII 134 ++ Sbjct: 173 NVLV 176 >gi|189163504 serine peptidase inhibitor, Kazal type 5 isoform c precursor [Homo sapiens] Length = 916 Score = 42.7 bits (99), Expect = 4e-04 Identities = 19/42 (45%), Positives = 25/42 (59%) Query: 58 CKPHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCK 99 C + VCG++GKTY N C L + TGS+I V +G CK Sbjct: 111 CPDYYEAVCGTDGKTYDNRCALCAENAKTGSQIGVKSEGECK 152 >gi|74027261 serine peptidase inhibitor, Kazal type 5 isoform b precursor [Homo sapiens] Length = 1064 Score = 42.7 bits (99), Expect = 4e-04 Identities = 19/42 (45%), Positives = 25/42 (59%) Query: 58 CKPHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCK 99 C + VCG++GKTY N C L + TGS+I V +G CK Sbjct: 111 CPDYYEAVCGTDGKTYDNRCALCAENAKTGSQIGVKSEGECK 152 Score = 35.8 bits (81), Expect = 0.049 Identities = 15/52 (28%), Positives = 26/52 (50%) Query: 58 CKPHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKEKKSVSPSAS 109 C +PVCG +G+TY N C L + + + + G C+E + +A+ Sbjct: 1006 CPKDLKPVCGDDGQTYNNPCMLCHENLIRQTNTHIRSTGKCEESSTPGTTAA 1057 >gi|189163501 serine peptidase inhibitor, Kazal type 5 isoform a precursor [Homo sapiens] Length = 1094 Score = 42.7 bits (99), Expect = 4e-04 Identities = 19/42 (45%), Positives = 25/42 (59%) Query: 58 CKPHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCK 99 C + VCG++GKTY N C L + TGS+I V +G CK Sbjct: 111 CPDYYEAVCGTDGKTYDNRCALCAENAKTGSQIGVKSEGECK 152 Score = 35.8 bits (81), Expect = 0.049 Identities = 15/52 (28%), Positives = 26/52 (50%) Query: 58 CKPHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKEKKSVSPSAS 109 C +PVCG +G+TY N C L + + + + G C+E + +A+ Sbjct: 1036 CPKDLKPVCGDDGQTYNNPCMLCHENLIRQTNTHIRSTGKCEESSTPGTTAA 1087 >gi|134031945 SCO-spondin [Homo sapiens] Length = 5147 Score = 41.2 bits (95), Expect = 0.001 Identities = 21/49 (42%), Positives = 26/49 (53%), Gaps = 5/49 (10%) Query: 220 KCLNPSFNPPEKKCALEDETYADGAETEVDCNRCVC-ACGNWVCTAMTC 267 +C+ PS P C L YA G+ T +CNRC+C G W CTA C Sbjct: 873 QCVPPSLCP----CQLGARRYAPGSATMKECNRCICQERGLWNCTARHC 917 Score = 37.0 bits (84), Expect = 0.022 Identities = 15/36 (41%), Positives = 18/36 (50%), Gaps = 1/36 (2%) Query: 233 CALEDETYADGAETEVD-CNRCVCACGNWVCTAMTC 267 C L + YA GA +D CN C C G CT+ C Sbjct: 2947 CQLHGQLYASGAMARLDSCNNCTCVSGKMACTSERC 2982 Score = 35.0 bits (79), Expect = 0.084 Identities = 17/53 (32%), Positives = 22/53 (41%), Gaps = 4/53 (7%) Query: 220 KCLNPSFNPPEKKCALEDETYADGAETEVDCNRCVCACGNWVCTAMTCDGKNQ 272 +C+ P P C + Y A + DCN CVC W CT G+ Q Sbjct: 967 RCVPPDLCP----CRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQ 1015 Score = 31.2 bits (69), Expect = 1.2 Identities = 11/32 (34%), Positives = 17/32 (53%) Query: 236 EDETYADGAETEVDCNRCVCACGNWVCTAMTC 267 + ++A G++ + CN C C G CTA C Sbjct: 4123 QGHSWAPGSQHQDACNNCSCQAGQLSCTAQPC 4154 Score = 30.4 bits (67), Expect = 2.1 Identities = 13/42 (30%), Positives = 18/42 (42%), Gaps = 4/42 (9%) Query: 221 CLNPSFNPPEKKCALEDETYADGAETEVDCNRCVCACGNWVC 262 CL P+ P C ++ G+ + DC C C G W C Sbjct: 1325 CLEPASCP----CEWGRNSFPPGSVLQKDCGNCTCQEGQWHC 1362 Score = 29.3 bits (64), Expect = 4.6 Identities = 11/30 (36%), Positives = 12/30 (40%) Query: 238 ETYADGAETEVDCNRCVCACGNWVCTAMTC 267 + Y G CN CVC G W C C Sbjct: 531 QRYVPGDTVRQLCNPCVCRDGRWHCAQALC 560 Score = 28.5 bits (62), Expect = 7.9 Identities = 11/31 (35%), Positives = 14/31 (45%) Query: 239 TYADGAETEVDCNRCVCACGNWVCTAMTCDG 269 T A G ++ C C C G CT+ C G Sbjct: 4491 TLAPGDRLQLGCKECECRRGELHCTSQGCQG 4521 >gi|4759164 sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1 precursor [Homo sapiens] Length = 439 Score = 40.4 bits (93), Expect = 0.002 Identities = 25/82 (30%), Positives = 33/82 (40%), Gaps = 7/82 (8%) Query: 57 QCKP----HKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHC---KEKKSVSPSAS 109 +CKP VCGS+G +Y + C+L AC TG + DG C E + A Sbjct: 135 KCKPCPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPCPCLPEPEPPKHKAE 194 Query: 110 PVVCYQSNRDELRRRIIQWLEA 131 C L R+ W A Sbjct: 195 RSACTDKELRNLASRLKDWFGA 216 >gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo sapiens] Length = 2134 Score = 40.4 bits (93), Expect = 0.002 Identities = 15/40 (37%), Positives = 20/40 (50%) Query: 228 PPEKKCALEDETYADGAETEVDCNRCVCACGNWVCTAMTC 267 P + C+ Y +G+ T V CN C C G+W CT C Sbjct: 1274 PNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWSCTQNEC 1313 Score = 29.3 bits (64), Expect = 4.6 Identities = 15/58 (25%), Positives = 22/58 (37%), Gaps = 1/58 (1%) Query: 230 EKKCALEDETYADGAETEVDC-NRCVCACGNWVCTAMTCDGKNQKGAQTQTEEEMTRY 286 E C Y G E C ++C C W CT C G+ + + T + +Y Sbjct: 816 ECPCESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCPGRCKVEGSSLTTFDGVKY 873 Score = 28.9 bits (63), Expect = 6.0 Identities = 14/43 (32%), Positives = 18/43 (41%), Gaps = 6/43 (13%) Query: 233 CALEDETYADGAETEVDCNRCVCACGNWVC------TAMTCDG 269 C + DE G +D N+CVC G +C T C G Sbjct: 1177 CYINDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSG 1219 >gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo sapiens] Length = 2134 Score = 40.4 bits (93), Expect = 0.002 Identities = 15/40 (37%), Positives = 20/40 (50%) Query: 228 PPEKKCALEDETYADGAETEVDCNRCVCACGNWVCTAMTC 267 P + C+ Y +G+ T V CN C C G+W CT C Sbjct: 1274 PNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWSCTQNEC 1313 Score = 29.3 bits (64), Expect = 4.6 Identities = 15/58 (25%), Positives = 22/58 (37%), Gaps = 1/58 (1%) Query: 230 EKKCALEDETYADGAETEVDC-NRCVCACGNWVCTAMTCDGKNQKGAQTQTEEEMTRY 286 E C Y G E C ++C C W CT C G+ + + T + +Y Sbjct: 816 ECPCESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEALCPGRCKVEGSSLTTFDGVKY 873 Score = 28.9 bits (63), Expect = 6.0 Identities = 14/43 (32%), Positives = 18/43 (41%), Gaps = 6/43 (13%) Query: 233 CALEDETYADGAETEVDCNRCVCACGNWVC------TAMTCDG 269 C + DE G +D N+CVC G +C T C G Sbjct: 1177 CYINDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSG 1219 >gi|161019170 mucin 5AC [Homo sapiens] Length = 6207 Score = 39.7 bits (91), Expect = 0.003 Identities = 17/43 (39%), Positives = 19/43 (44%), Gaps = 2/43 (4%) Query: 229 PEKKCAL--EDETYADGAETEVDCNRCVCACGNWVCTAMTCDG 269 P KCA YA GA DC C C+ G W C + C G Sbjct: 390 PVSKCACVYNGAAYAPGATYSTDCTNCTCSGGRWSCQEVPCPG 432 Score = 38.9 bits (89), Expect = 0.006 Identities = 22/83 (26%), Positives = 32/83 (38%), Gaps = 21/83 (25%) Query: 221 CLNPSFNPPEKKCALEDE-------------------TYADGAETEVDCNRCVCACGNWV 261 C++ F PP + C + D+ TY+ G C+ C C+ G W Sbjct: 1015 CVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSFNTTCSSCTCSGGLWQ 1074 Query: 262 CTAMTCDG--KNQKGAQTQTEEE 282 C + C G Q GA T +E Sbjct: 1075 CQDLPCPGTCSVQGGAHISTYDE 1097 Score = 36.2 bits (82), Expect = 0.038 Identities = 14/37 (37%), Positives = 16/37 (43%) Query: 233 CALEDETYADGAETEVDCNRCVCACGNWVCTAMTCDG 269 C + TY G VDCN C C W C+ C G Sbjct: 1516 CVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLG 1552 >gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens] Length = 2852 Score = 39.7 bits (91), Expect = 0.003 Identities = 14/40 (35%), Positives = 17/40 (42%) Query: 228 PPEKKCALEDETYADGAETEVDCNRCVCACGNWVCTAMTC 267 P E C Y G+ + DCN C C G W C+ C Sbjct: 398 PAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVC 437 Score = 33.5 bits (75), Expect = 0.24 Identities = 16/52 (30%), Positives = 24/52 (46%) Query: 216 QEFLKCLNPSFNPPEKKCALEDETYADGAETEVDCNRCVCACGNWVCTAMTC 267 Q L+ + F P E C + + Y G + C+ CVC G++ CT C Sbjct: 858 QGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPC 909 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.131 0.414 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,368,347 Number of Sequences: 37866 Number of extensions: 647993 Number of successful extensions: 2204 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 58 Number of HSP's successfully gapped in prelim test: 40 Number of HSP's that attempted gapping in prelim test: 2002 Number of HSP's gapped (non-prelim): 231 length of query: 308 length of database: 18,247,518 effective HSP length: 102 effective length of query: 206 effective length of database: 14,385,186 effective search space: 2963348316 effective search space used: 2963348316 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.