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Search of human proteins with 58331211
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|58331211 elastase 2B preproprotein [Homo sapiens]
(269 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|58331211 elastase 2B preproprotein [Homo sapiens] 566 e-162
gi|15559207 elastase 2A preproprotein [Homo sapiens] 503 e-143
gi|62526043 chymotrypsin C preproprotein [Homo sapiens] 319 2e-87
gi|236460050 elastase 3A, pancreatic preproprotein [Homo sapiens] 305 4e-83
gi|6679625 elastase 3B, pancreatic preproprotein [Homo sapiens] 301 5e-82
gi|58331209 chymotrypsin-like elastase family, member 1 [Homo sa... 285 4e-77
gi|4503137 chymotrypsin-like [Homo sapiens] 190 1e-48
gi|118498341 chymotrypsin B1 [Homo sapiens] 166 3e-41
gi|33695155 hepsin [Homo sapiens] 162 3e-40
gi|4504481 hepsin [Homo sapiens] 162 3e-40
gi|118498350 chymotrypsin B2 [Homo sapiens] 162 4e-40
gi|68508970 tryptase beta 2 precursor [Homo sapiens] 159 2e-39
gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens] 158 4e-39
gi|110815798 ovochymase 1 [Homo sapiens] 156 2e-38
gi|4758508 transmembrane protease, serine 11D [Homo sapiens] 156 2e-38
gi|58218970 protease, serine, 36 [Homo sapiens] 155 3e-38
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa... 155 3e-38
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa... 155 3e-38
gi|148613878 acrosin precursor [Homo sapiens] 155 3e-38
gi|4505881 plasminogen [Homo sapiens] 155 5e-38
gi|117956391 protease, serine, 33 [Homo sapiens] 153 2e-37
gi|29244926 corin [Homo sapiens] 148 6e-36
gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sa... 147 7e-36
gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo sap... 147 7e-36
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 147 7e-36
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens] 147 1e-35
gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens] 144 8e-35
gi|4506153 prostasin preproprotein [Homo sapiens] 144 1e-34
gi|187761337 transmembrane protease, serine 11B [Homo sapiens] 143 2e-34
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 142 2e-34
>gi|58331211 elastase 2B preproprotein [Homo sapiens]
Length = 269
Score = 566 bits (1459), Expect = e-162
Identities = 269/269 (100%), Positives = 269/269 (100%)
Query: 1 MIRTLLLSTLVAGALSCGVSTYAPDMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGG 60
MIRTLLLSTLVAGALSCGVSTYAPDMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGG
Sbjct: 1 MIRTLLLSTLVAGALSCGVSTYAPDMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGG 60
Query: 61 SLIANSWVLTAAHCISSSGIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGN 120
SLIANSWVLTAAHCISSSGIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGN
Sbjct: 61 SLIANSWVLTAAHCISSSGIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGN 120
Query: 121 DIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRLLV 180
DIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRLLV
Sbjct: 121 DIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRLLV 180
Query: 181 VDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSV 240
VDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSV
Sbjct: 181 VDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSV 240
Query: 241 LGCNYYYKPSIFTRVSNYNDWINSVIANN 269
LGCNYYYKPSIFTRVSNYNDWINSVIANN
Sbjct: 241 LGCNYYYKPSIFTRVSNYNDWINSVIANN 269
>gi|15559207 elastase 2A preproprotein [Homo sapiens]
Length = 269
Score = 503 bits (1294), Expect = e-143
Identities = 238/269 (88%), Positives = 254/269 (94%)
Query: 1 MIRTLLLSTLVAGALSCGVSTYAPDMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGG 60
MIRTLLLSTLVAGALSCG TY P ++R++GGEEARPNSWPWQVSLQYSSNG+WYHTCGG
Sbjct: 1 MIRTLLLSTLVAGALSCGDPTYPPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGG 60
Query: 61 SLIANSWVLTAAHCISSSGIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGN 120
SLIANSWVLTAAHCISSS YRV LG+HNLYVAESGSLAVSVSKIVVHKDWNS+Q+SKGN
Sbjct: 61 SLIANSWVLTAAHCISSSRTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGN 120
Query: 121 DIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRLLV 180
DIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGA+PD L+QGRLLV
Sbjct: 121 DIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLV 180
Query: 181 VDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSV 240
VDYATCSSS WWGS+VKT+MICAGGDGVI +CNGDSGGPLNCQASDGRW+VHGI S S
Sbjct: 181 VDYATCSSSAWWGSSVKTSMICAGGDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSR 240
Query: 241 LGCNYYYKPSIFTRVSNYNDWINSVIANN 269
LGCNYY+KPS+FTRVSNY DWINSVIANN
Sbjct: 241 LGCNYYHKPSVFTRVSNYIDWINSVIANN 269
>gi|62526043 chymotrypsin C preproprotein [Homo sapiens]
Length = 268
Score = 319 bits (817), Expect = 2e-87
Identities = 157/265 (59%), Positives = 194/265 (73%), Gaps = 4/265 (1%)
Query: 1 MIRTLLLSTLVAGALSCGVSTYAPDMS-RMLGGEEARPNSWPWQVSLQYSSNGQWYHTCG 59
M+ +L+ L+A A SCGV ++ P++S R++GGE+ARP+SWPWQ+SLQY N W HTCG
Sbjct: 1 MLGITVLAALLACASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCG 60
Query: 60 GSLIANSWVLTAAHCISSSGIYRVMLGQHNLYVA-ESGSLAVSVSKIVVHKDWNSDQVSK 118
G+LIA+++VLTAAHCIS++ YRV +G++NL V E GSL V V I VHK WN+ +
Sbjct: 61 GTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNA--LLL 118
Query: 119 GNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRL 178
NDIAL+KLA V L+D IQ+ACLP ++LP +YPCYVTGWGRL TNG + D L+QG
Sbjct: 119 RNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQ 178
Query: 179 LVVDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLT 238
VVD+ATCS WWG VK M+CAGGDGVI CNGDSGGPLNCQ +G WEV GI S
Sbjct: 179 PVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFG 238
Query: 239 SVLGCNYYYKPSIFTRVSNYNDWIN 263
S GCN KP ++TRVS Y DWIN
Sbjct: 239 SRRGCNTRKKPVVYTRVSAYIDWIN 263
>gi|236460050 elastase 3A, pancreatic preproprotein [Homo sapiens]
Length = 270
Score = 305 bits (780), Expect = 4e-83
Identities = 149/270 (55%), Positives = 185/270 (68%), Gaps = 10/270 (3%)
Query: 6 LLSTLVAGALSCGVSTYAP----DMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGS 61
LLS+L+ A++ G Y P SR++ GE+A P SWPWQVSLQY +G +YHTCGGS
Sbjct: 5 LLSSLLLVAVASG---YGPPSSHSSSRVVHGEDAVPYSWPWQVSLQYEKSGSFYHTCGGS 61
Query: 62 LIANSWVLTAAHCISSSGIYRVMLGQHNLYVAESGSLAVSVS--KIVVHKDWNSDQVSKG 119
LIA WV+TA HCIS Y+V+LG++NL V E + ++ ++ VH WN V+ G
Sbjct: 62 LIAPDWVVTAGHCISRDLTYQVVLGEYNLAVKEGPEQVIPINSEELFVHPLWNRSCVACG 121
Query: 120 NDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRLL 179
NDIAL+KL+ L D +QLA LPPAG ILPN PCY+TGWGRL TNG LPD L+Q RL
Sbjct: 122 NDIALIKLSRSAQLGDAVQLASLPPAGDILPNKTPCYITGWGRLYTNGPLPDKLQQARLP 181
Query: 180 VVDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTS 239
VVDY CS WWGSTVK M+CAGG + CNGDSGGPLNC DG W+VHG+ S S
Sbjct: 182 VVDYKHCSRWNWWGSTVKKTMVCAGG-YIRSGCNGDSGGPLNCPTEDGGWQVHGVTSFVS 240
Query: 240 VLGCNYYYKPSIFTRVSNYNDWINSVIANN 269
GCN+ +KP++FTRVS + DWI IA++
Sbjct: 241 AFGCNFIWKPTVFTRVSAFIDWIEETIASH 270
>gi|6679625 elastase 3B, pancreatic preproprotein [Homo sapiens]
Length = 270
Score = 301 bits (770), Expect = 5e-82
Identities = 148/271 (54%), Positives = 182/271 (67%), Gaps = 4/271 (1%)
Query: 1 MIRTLLLSTLVAGALSCGVSTYAPDMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGG 60
M+R L LVA A G + P SR++ GE+A P SWPWQVSLQY +G +YHTCGG
Sbjct: 2 MLRLLSSLLLVAVASGYGPPSSRPS-SRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGG 60
Query: 61 SLIANSWVLTAAHCISSSGIYRVMLGQHNLYVAESGSLAVSVSK--IVVHKDWNSDQVSK 118
SLIA WV+TA HCISSS Y+V+LG+++ V E + ++ + VH WN V+
Sbjct: 61 SLIAPDWVVTAGHCISSSRTYQVVLGEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVAC 120
Query: 119 GNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRL 178
GNDIAL+KL+ L D +QLA LPPAG ILPN PCY+TGWGRL TNG LPD L++ L
Sbjct: 121 GNDIALIKLSRSAQLGDAVQLASLPPAGDILPNETPCYITGWGRLYTNGPLPDKLQEALL 180
Query: 179 LVVDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLT 238
VVDY CS WWGS+VK M+CAGGD + CNGDSGGPLNC DG W+VHG+ S
Sbjct: 181 PVVDYEHCSRWNWWGSSVKKTMVCAGGD-IRSGCNGDSGGPLNCPTEDGGWQVHGVTSFV 239
Query: 239 SVLGCNYYYKPSIFTRVSNYNDWINSVIANN 269
S GCN KP++FTRVS + DWI IA++
Sbjct: 240 SAFGCNTRRKPTVFTRVSAFIDWIEETIASH 270
>gi|58331209 chymotrypsin-like elastase family, member 1 [Homo
sapiens]
Length = 258
Score = 285 bits (728), Expect = 4e-77
Identities = 137/243 (56%), Positives = 168/243 (69%), Gaps = 1/243 (0%)
Query: 27 SRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAHCISSSGIYRVMLG 86
+R++GG EA NSWP Q+SLQY S G YHTCGG+LI +WV+TAAHC+ +RV+ G
Sbjct: 17 ARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQKTFRVVAG 76
Query: 87 QHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGNDIALLKLANPVSLTDKIQLACLPPAG 146
HNL + VSV KIVVH WNSD V+ G DIALL+LA V+L +QL LP G
Sbjct: 77 DHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVLPQEG 136
Query: 147 TILPNNYPCYVTGWGRLQTNGALPDDLKQGRLLVVDYATCSSSGWWGSTVKTNMICAGGD 206
IL NN PCY+TGWG+ +TNG L L+Q L VDYA CSSS +WGSTVK M+CAGGD
Sbjct: 137 AILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVCAGGD 196
Query: 207 GVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSVLGCNYYYKPSIFTRVSNYNDWINSVI 266
GV C GDSGGPL+C +G++ VHG+ S S GCN KP++FT+VS Y WIN+VI
Sbjct: 197 GVRSGCQGDSGGPLHCLV-NGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWINNVI 255
Query: 267 ANN 269
A+N
Sbjct: 256 ASN 258
>gi|4503137 chymotrypsin-like [Homo sapiens]
Length = 264
Score = 190 bits (482), Expect = 1e-48
Identities = 115/274 (41%), Positives = 155/274 (56%), Gaps = 16/274 (5%)
Query: 1 MIRTLLLSTLVAGAL-SCGVSTYAPDMS---RMLGGEEARPNSWPWQVSLQYSSNGQWYH 56
++ +L LS ++ G+ CG+ P +S R++ GE A SWPWQVSLQ SS +H
Sbjct: 2 LLLSLTLSLVLLGSSWGCGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSG---FH 58
Query: 57 TCGGSLIANSWVLTAAHCISSSGIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQV 116
CGGSLI+ SWV+TAAHC S G + V+LG+++ +SVS+ + H WNS
Sbjct: 59 FCGGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNS--T 116
Query: 117 SKGNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNG-ALPDDLKQ 175
+ ND+ LLKLA+P T +I CL + L C TGWGRL G P L+Q
Sbjct: 117 TMNNDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQ 176
Query: 176 GRLLVVDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGIG 235
L +V C +WGS++ +MICAGG G +C GDSGGPL CQ + W + GI
Sbjct: 177 VALPLVTVNQCRQ--YWGSSITDSMICAGGAGA-SSCQGDSGGPLVCQKGN-TWVLIGIV 232
Query: 236 SLTSVLGCNYYYKPSIFTRVSNYNDWINSVIANN 269
S CN P+++TRVS ++ WIN VIA N
Sbjct: 233 S-WGTKNCN-VRAPAVYTRVSKFSTWINQVIAYN 264
>gi|118498341 chymotrypsin B1 [Homo sapiens]
Length = 263
Score = 166 bits (419), Expect = 3e-41
Identities = 104/266 (39%), Positives = 142/266 (53%), Gaps = 18/266 (6%)
Query: 9 TLVAGALSCGVSTYAP---DMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIAN 65
+LV A CGV P +SR++ GE+A P SWPWQVSLQ + +H CGGSLI+
Sbjct: 11 SLVGAAFGCGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQDKTG---FHFCGGSLISE 67
Query: 66 SWVLTAAHC-ISSSGIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGNDIAL 124
WV+TAAHC + +S + V+ G+ + E + ++K V K+ ++ NDI L
Sbjct: 68 DWVVTAAHCGVRTSDV--VVAGEFDQGSDEENIQVLKIAK--VFKNPKFSILTVNNDITL 123
Query: 125 LKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTN-GALPDDLKQGRLLVVDY 183
LKLA P + + CLP A P C TGWG+ + N PD L+Q L ++
Sbjct: 124 LKLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKLQQAALPLLSN 183
Query: 184 ATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSVLGC 243
A C S WG + MICAG GV +C GDSGGPL CQ DG W + GI S S C
Sbjct: 184 AECKKS--WGRRITDVMICAGASGV-SSCMGDSGGPLVCQ-KDGAWTLVGIVSWGSDT-C 238
Query: 244 NYYYKPSIFTRVSNYNDWINSVIANN 269
+ P ++ RV+ W+ ++A N
Sbjct: 239 S-TSSPGVYARVTKLIPWVQKILAAN 263
>gi|33695155 hepsin [Homo sapiens]
Length = 417
Score = 162 bits (410), Expect = 3e-40
Identities = 97/255 (38%), Positives = 138/255 (54%), Gaps = 24/255 (9%)
Query: 26 MSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAHCISSSGI----Y 81
+ R++GG + WPWQVSL+Y H CGGSL++ WVLTAAHC +
Sbjct: 160 VDRIVGGRDTSLGRWPWQVSLRYDGA----HLCGGSLLSGDWVLTAAHCFPERNRVLSRW 215
Query: 82 RVMLGQHNLYVAESGSLAVSVSKIVVH------KDWNSDQVSKGNDIALLKLANPVSLTD 135
RV G + A L + V +V H +D NS++ S NDIAL+ L++P+ LT+
Sbjct: 216 RVFAGA--VAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENS--NDIALVHLSSPLPLTE 271
Query: 136 KIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRLLVVDYATCSSSGWWGST 195
IQ CLP AG L + C VTGWG Q G L++ R+ ++ C+ + ++G+
Sbjct: 272 YIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQ 331
Query: 196 VKTNMICAG-GDGVICTCNGDSGGPLNCQAS---DGRWEVHGIGSLTSVLGCNYYYKPSI 251
+K M CAG +G I C GDSGGP C+ S RW + GI S + GC KP +
Sbjct: 332 IKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGT--GCALAQKPGV 389
Query: 252 FTRVSNYNDWINSVI 266
+T+VS++ +WI I
Sbjct: 390 YTKVSDFREWIFQAI 404
>gi|4504481 hepsin [Homo sapiens]
Length = 417
Score = 162 bits (410), Expect = 3e-40
Identities = 97/255 (38%), Positives = 138/255 (54%), Gaps = 24/255 (9%)
Query: 26 MSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAHCISSSGI----Y 81
+ R++GG + WPWQVSL+Y H CGGSL++ WVLTAAHC +
Sbjct: 160 VDRIVGGRDTSLGRWPWQVSLRYDGA----HLCGGSLLSGDWVLTAAHCFPERNRVLSRW 215
Query: 82 RVMLGQHNLYVAESGSLAVSVSKIVVH------KDWNSDQVSKGNDIALLKLANPVSLTD 135
RV G + A L + V +V H +D NS++ S NDIAL+ L++P+ LT+
Sbjct: 216 RVFAGA--VAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENS--NDIALVHLSSPLPLTE 271
Query: 136 KIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRLLVVDYATCSSSGWWGST 195
IQ CLP AG L + C VTGWG Q G L++ R+ ++ C+ + ++G+
Sbjct: 272 YIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQ 331
Query: 196 VKTNMICAG-GDGVICTCNGDSGGPLNCQAS---DGRWEVHGIGSLTSVLGCNYYYKPSI 251
+K M CAG +G I C GDSGGP C+ S RW + GI S + GC KP +
Sbjct: 332 IKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGT--GCALAQKPGV 389
Query: 252 FTRVSNYNDWINSVI 266
+T+VS++ +WI I
Sbjct: 390 YTKVSDFREWIFQAI 404
>gi|118498350 chymotrypsin B2 [Homo sapiens]
Length = 263
Score = 162 bits (409), Expect = 4e-40
Identities = 102/265 (38%), Positives = 141/265 (53%), Gaps = 18/265 (6%)
Query: 10 LVAGALSCGVSTYAP---DMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANS 66
L+ CGV P +SR++ GE+A P SWPWQVSLQ + +H CGGSLI+
Sbjct: 12 LLGTTFGCGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQDKTG---FHFCGGSLISED 68
Query: 67 WVLTAAHC-ISSSGIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGNDIALL 125
WV+TAAHC + +S + V+ G+ + E + ++K V K+ ++ NDI LL
Sbjct: 69 WVVTAAHCGVRTSDV--VVAGEFDQGSDEENIQVLKIAK--VFKNPKFSILTVNNDITLL 124
Query: 126 KLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTN-GALPDDLKQGRLLVVDYA 184
KLA P + + CLP A P C TGWG+ + N PD L+Q L ++ A
Sbjct: 125 KLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKLQQAALPLLSNA 184
Query: 185 TCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSVLGCN 244
C S WG + MICAG GV +C GDSGGPL CQ DG W + GI S S C+
Sbjct: 185 ECKKS--WGRRITDVMICAGASGV-SSCMGDSGGPLVCQ-KDGAWTLVGIVSWGS-RTCS 239
Query: 245 YYYKPSIFTRVSNYNDWINSVIANN 269
P+++ RV+ W+ ++A N
Sbjct: 240 -TTTPAVYARVAKLIPWVQKILAAN 263
>gi|68508970 tryptase beta 2 precursor [Homo sapiens]
Length = 275
Score = 159 bits (402), Expect = 2e-39
Identities = 100/275 (36%), Positives = 144/275 (52%), Gaps = 23/275 (8%)
Query: 5 LLLSTLVAGALSCGVSTYAPDMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIA 64
L L L + A + A ++GG+EA + WPWQVSL+ W H CGGSLI
Sbjct: 7 LALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVRDR-YWMHFCGGSLIH 65
Query: 65 NSWVLTAAHCISSS----GIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGN 120
WVLTAAHC+ RV L + +LY + + VS+I+VH + + Q+ G
Sbjct: 66 PQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQ---LLPVSRIIVHPQFYTAQI--GA 120
Query: 121 DIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPD--DLKQGRL 178
DIALL+L PV+++ + LPPA P PC+VTGWG + + LP LKQ ++
Sbjct: 121 DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180
Query: 179 LVVDYATCSSSGWWGS-------TVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEV 231
+++ C + G+ V+ +M+CAG +C GDSGGPL C+ +G W
Sbjct: 181 PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTR-RDSCQGDSGGPLVCKV-NGTWLQ 238
Query: 232 HGIGSLTSVLGCNYYYKPSIFTRVSNYNDWINSVI 266
G+ S GC +P I+TRV+ Y DWI+ +
Sbjct: 239 AGVVSWGE--GCAQPNRPGIYTRVTYYLDWIHHYV 271
>gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]
Length = 275
Score = 158 bits (400), Expect = 4e-39
Identities = 100/275 (36%), Positives = 144/275 (52%), Gaps = 23/275 (8%)
Query: 5 LLLSTLVAGALSCGVSTYAPDMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIA 64
L L L + A + A ++GG+EA + WPWQVSL+ W H CGGSLI
Sbjct: 7 LALPVLASRAYAAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGP-YWMHFCGGSLIH 65
Query: 65 NSWVLTAAHCISSS----GIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGN 120
WVLTAAHC+ RV L + +LY + + VS+I+VH + + Q+ G
Sbjct: 66 PQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQ---LLPVSRIIVHPQFYTAQI--GA 120
Query: 121 DIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPD--DLKQGRL 178
DIALL+L PV+++ + LPPA P PC+VTGWG + + LP LKQ ++
Sbjct: 121 DIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKV 180
Query: 179 LVVDYATCSSSGWWGS-------TVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEV 231
+++ C + G+ V+ +M+CAG +C GDSGGPL C+ +G W
Sbjct: 181 PIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTR-RDSCQGDSGGPLVCKV-NGTWLQ 238
Query: 232 HGIGSLTSVLGCNYYYKPSIFTRVSNYNDWINSVI 266
G+ S GC +P I+TRV+ Y DWI+ +
Sbjct: 239 AGVVSWGE--GCAQPNRPGIYTRVTYYLDWIHHYV 271
>gi|110815798 ovochymase 1 [Homo sapiens]
Length = 1134
Score = 156 bits (395), Expect = 2e-38
Identities = 91/259 (35%), Positives = 143/259 (55%), Gaps = 17/259 (6%)
Query: 17 CGVSTYAPDM--SRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAHC 74
CG+ ++P R+ GGEEA P+ WPWQV L++ + Q CGG++I W+LTAAHC
Sbjct: 561 CGIPPFSPQWLSRRIAGGEEACPHCWPWQVGLRFLGDYQ----CGGAIINPVWILTAAHC 616
Query: 75 ISSSG---IYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGNDIALLKLANPV 131
+ + ++ G H+ + ES I+VH+D+N+ +S +DIAL++L++P+
Sbjct: 617 VQLKNNPLSWTIIAGDHDRNLKESTEQVRRAKHIIVHEDFNT--LSYDSDIALIQLSSPL 674
Query: 132 SLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRLLVVDYATCSSSGW 191
++ CLP + L ++ C VTGWG + +G L L+Q ++ V++ C + +
Sbjct: 675 EYNSVVRPVCLPHSAEPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYY 734
Query: 192 WG--STVKTNMICAG--GDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSVLGCNYYY 247
+ MICAG G C GDSGGPL C+ +G + ++GI S + GC +
Sbjct: 735 SAHPGGITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGA--GCVQPW 792
Query: 248 KPSIFTRVSNYNDWINSVI 266
KP +F RV + DWI S I
Sbjct: 793 KPGVFARVMIFLDWIQSKI 811
Score = 111 bits (277), Expect = 8e-25
Identities = 82/254 (32%), Positives = 123/254 (48%), Gaps = 25/254 (9%)
Query: 27 SRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAHCISSSGIYR---- 82
SR+ + PWQVSL+ +H CGGSLI V+TAAHC+ S +
Sbjct: 45 SRISSWRNSTVTGHPWQVSLKSDE----HHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNI 100
Query: 83 -VMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGNDIALLKLANPVSLTDKIQLAC 141
V G+++L+ + + VSKI+ H ++NS + DIALL L + V + +Q C
Sbjct: 101 TVTSGEYSLFQKDKQEQNIPVSKIITHPEYNSREYMSP-DIALLYLKHKVKFGNAVQPIC 159
Query: 142 LPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRLLVVDYATCSS--SGWWGSTVKTN 199
LP + + C +GWG++ + L++ L ++D C++ +
Sbjct: 160 LPDSDDKVEPGILCLSSGWGKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRT 219
Query: 200 MICAG-GDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSVLGC--------NYYYKPS 250
M+CAG D + C GDSGGPL C+ G W + GI S V GC N + K S
Sbjct: 220 MLCAGFPDWGMDACQGDSGGPLVCRRGGGIWILAGITSW--VAGCAGGSVPVRNNHVKAS 277
Query: 251 --IFTRVSNYNDWI 262
IF++VS D+I
Sbjct: 278 LGIFSKVSELMDFI 291
>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
Length = 418
Score = 156 bits (394), Expect = 2e-38
Identities = 90/236 (38%), Positives = 127/236 (53%), Gaps = 10/236 (4%)
Query: 28 RMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAHCISSSGIYRVMLGQ 87
R+LGG EA SWPWQVSL+ ++ H CGGSLI N W+LTAAHC S+ R +
Sbjct: 186 RILGGTEAEEGSWPWQVSLRLNNA----HHCGGSLINNMWILTAAHCFRSNSNPRDWIAT 241
Query: 88 HNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGNDIALLKLANPVSLTDKIQLACLPPAGT 147
+ L + V I++H ++ S + NDIAL++L N V+ T I CLP A
Sbjct: 242 SGISTTFP-KLRMRVRNILIHNNYKS--ATHENDIALVRLENSVTFTKDIHSVCLPAATQ 298
Query: 148 ILPNNYPCYVTGWGRLQTNGALPDDLKQGRLLVVDYATCSSSGWWGSTVKTNMICAG-GD 206
+P YVTGWG + G +L+QG++ ++ C++ + + + M+CAG
Sbjct: 299 NIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGMLCAGVPQ 358
Query: 207 GVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSVLGCNYYYKPSIFTRVSNYNDWI 262
G + C GDSGGPL + S W + GI S C KP ++TRV+ Y DWI
Sbjct: 359 GGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGD--QCGLPDKPGVYTRVTAYLDWI 412
>gi|58218970 protease, serine, 36 [Homo sapiens]
Length = 855
Score = 155 bits (393), Expect = 3e-38
Identities = 105/268 (39%), Positives = 144/268 (53%), Gaps = 29/268 (10%)
Query: 15 LSCGVSTYAPDMS-RMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAH 73
L CG P+ S R++GG A+P +WPWQVSL + H CGGSLIA SWVL+AAH
Sbjct: 36 LDCG----RPEPSARIVGGSNAQPGTWPWQVSLHHGGG----HICGGSLIAPSWVLSAAH 87
Query: 74 CISSSGI------YRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGNDIALLKL 127
C ++G + V+LG H+ G+ +V+ IVV +++ QV G D+ALL+L
Sbjct: 88 CFMTNGTLEPAAEWSVLLGVHSQDGPLDGAHTRAVAAIVVPANYS--QVELGADLALLRL 145
Query: 128 ANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDD--LKQGRLLVVDYAT 185
A+P SL + CLP A + C+ TGWG +Q LP L++ L ++ AT
Sbjct: 146 ASPASLGPAVWPVCLPRASHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEAT 205
Query: 186 C----SSSGWWGSTVK--TNMICAG-GDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLT 238
C S G + T++ M+CAG +G TC GDSGGPL C+ GRW GI S
Sbjct: 206 CQCLYSQPGPFNLTLQILPGMLCAGYPEGRRDTCQGDSGGPLVCE-EGGRWFQAGITSFG 264
Query: 239 SVLGCNYYYKPSIFTRVSNYNDWINSVI 266
GC +P +FT V+ Y WI +
Sbjct: 265 --FGCGRRNRPGVFTAVATYEAWIREQV 290
Score = 68.9 bits (167), Expect = 4e-12
Identities = 73/260 (28%), Positives = 110/260 (42%), Gaps = 58/260 (22%)
Query: 32 GEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAHCI---SSS-------GIY 81
G+ RP +WPW+ + + C G+L++ SWVL A C +SS +
Sbjct: 326 GKAPRPGAWPWEAQVMVPGS----RPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAW 381
Query: 82 RVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGNDIALLKLANPVSLTDKIQLAC 141
RV+L S A V+++V H++ + D S D+ALL+L PV+L+ + C
Sbjct: 382 RVLL--------PSRPRAERVARLVQHENASWDNAS---DLALLQLRTPVNLSAASRPVC 430
Query: 142 LP-PAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRLLVVDYATCSSSGWW-------- 192
LP P LP + C + WGR + P L + LL GWW
Sbjct: 431 LPHPEHYFLPGS-RCRLARWGRGEP-ALGPGALLEAELL---------GGWWCHCLYGRQ 479
Query: 193 GSTV-----KTNMICAG--GDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSVLGCNY 245
G+ V + +C + +C DS L CQ +G W + GI S GC
Sbjct: 480 GAAVPLPGDPPHALCPAYQEKEEVGSCWNDSRWSLLCQ-EEGTWFLAGIRDFPS--GC-- 534
Query: 246 YYKPSIFTRVSNYNDWINSV 265
+P F + + WI+ V
Sbjct: 535 -LRPRAFFPLQTHGPWISHV 553
Score = 55.1 bits (131), Expect = 6e-08
Identities = 50/200 (25%), Positives = 83/200 (41%), Gaps = 21/200 (10%)
Query: 40 WPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAHCISSSGIYRVMLGQHNLYVAESGSLA 99
WPW + + + C G L+A WVL A HC+ G V + +Y+ +G+ +
Sbjct: 601 WPWLAEVHVAGD----RVCTGILLAPGWVLAATHCVLRPGSTTVPYIE--VYLGRAGASS 654
Query: 100 V----SVSKIVVHKDWNSDQVSKGNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPC 155
+ VS++V+ + +ALL+L++ V + CL PAG +P C
Sbjct: 655 LPQGHQVSRLVISIRL-PQHLGLRPPLALLELSSRVEPSPSALPICLHPAG--IPPGASC 711
Query: 156 YVTGWGRLQTNGALPDDLKQGRLLVVDYATCSSSGWWGSTVKTNMICA-GGDGVICTCNG 214
+V GW Q + + +L C G + +C +G C
Sbjct: 712 WVLGWKEPQDRVPVAAAVS---ILTQRICDCLYQG----ILPPGTLCVLYAEGQENRCEM 764
Query: 215 DSGGPLNCQASDGRWEVHGI 234
S PL CQ ++G W + G+
Sbjct: 765 TSAPPLLCQMTEGSWILVGM 784
>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
sapiens]
Length = 529
Score = 155 bits (392), Expect = 3e-38
Identities = 88/258 (34%), Positives = 134/258 (51%), Gaps = 25/258 (9%)
Query: 15 LSCGVSTYAPDMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAHC 74
++CGV+ + SR++GGE A P +WPWQVSL + H CGGS+I W++TAAHC
Sbjct: 279 IACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQN----VHVCGGSIITPEWIVTAAHC 334
Query: 75 ISSSGIYRVMLGQHNLYVAESGSLAVS---------VSKIVVHKDWNSDQVSKGNDIALL 125
+ L + A +G L S V K++ H N D +K NDIAL+
Sbjct: 335 VEKP------LNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHP--NYDSKTKNNDIALM 386
Query: 126 KLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRLLVVDYAT 185
KL P++ D ++ CLP G +L C+++GWG + G + L ++L+++
Sbjct: 387 KLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQR 446
Query: 186 CSSSGWWGSTVKTNMICAGG-DGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSVLGCN 244
C+S + + + MICAG G + +C GDSGGPL ++ W IG + GC
Sbjct: 447 CNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWL---IGDTSWGSGCA 503
Query: 245 YYYKPSIFTRVSNYNDWI 262
Y+P ++ V + DWI
Sbjct: 504 KAYRPGVYGNVMVFTDWI 521
>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
sapiens]
Length = 492
Score = 155 bits (392), Expect = 3e-38
Identities = 88/258 (34%), Positives = 134/258 (51%), Gaps = 25/258 (9%)
Query: 15 LSCGVSTYAPDMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAHC 74
++CGV+ + SR++GGE A P +WPWQVSL + H CGGS+I W++TAAHC
Sbjct: 242 IACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQN----VHVCGGSIITPEWIVTAAHC 297
Query: 75 ISSSGIYRVMLGQHNLYVAESGSLAVS---------VSKIVVHKDWNSDQVSKGNDIALL 125
+ L + A +G L S V K++ H N D +K NDIAL+
Sbjct: 298 VEKP------LNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHP--NYDSKTKNNDIALM 349
Query: 126 KLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRLLVVDYAT 185
KL P++ D ++ CLP G +L C+++GWG + G + L ++L+++
Sbjct: 350 KLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQR 409
Query: 186 CSSSGWWGSTVKTNMICAGG-DGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSVLGCN 244
C+S + + + MICAG G + +C GDSGGPL ++ W IG + GC
Sbjct: 410 CNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWL---IGDTSWGSGCA 466
Query: 245 YYYKPSIFTRVSNYNDWI 262
Y+P ++ V + DWI
Sbjct: 467 KAYRPGVYGNVMVFTDWI 484
>gi|148613878 acrosin precursor [Homo sapiens]
Length = 421
Score = 155 bits (392), Expect = 3e-38
Identities = 92/255 (36%), Positives = 143/255 (56%), Gaps = 17/255 (6%)
Query: 28 RMLGGEEARPNSWPWQVSLQ-YSSNGQWYHTCGGSLIANSWVLTAAHC-ISSSGI--YRV 83
R++GG+ A+ +WPW VSLQ ++ N YHTCGGSL+ + WVLTAAHC + + + +R+
Sbjct: 42 RIVGGKAAQHGAWPWMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHDWRL 101
Query: 84 MLGQHNLYVAESGSLAVS-----VSKIVVHKDWNSDQVSKGNDIALLKLANPVSLTDKIQ 138
+ G + + + V KI++H+ +NS ++GNDIAL+++ P+S I
Sbjct: 102 VFGAKEITYGNNKPVKAPLQERYVEKIIIHEKYNS--ATEGNDIALVEITPPISCGRFIG 159
Query: 139 LACLPPAGTILP-NNYPCYVTGWGRLQTNGALPDD-LKQGRLLVVDYATCSSSGWWGSTV 196
CLP LP + C+V GWG ++ P L + R+ ++D C+S+ W+ V
Sbjct: 160 PGCLPHFKAGLPRGSQSCWVAGWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRV 219
Query: 197 KTNMICAGGD-GVICTCNGDSGGPLNCQASDGRWEVHGIGSLTS-VLGCNYYYKPSIFTR 254
+ +CAG G I TC GDSGGPL C+ D + + + +TS +GC +P I+T
Sbjct: 220 QPTNVCAGYPVGKIDTCQGDSGGPLMCK--DSKESAYVVVGITSWGVGCARAKRPGIYTA 277
Query: 255 VSNYNDWINSVIANN 269
Y +WI S I +N
Sbjct: 278 TWPYLNWIASKIGSN 292
>gi|4505881 plasminogen [Homo sapiens]
Length = 810
Score = 155 bits (391), Expect = 5e-38
Identities = 99/265 (37%), Positives = 140/265 (52%), Gaps = 23/265 (8%)
Query: 12 AGALSCGVSTYAPDM--SRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANSWVL 69
A + CG P R++GG A P+SWPWQVSL+ H CGG+LI+ WVL
Sbjct: 562 APSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFG---MHFCGGTLISPEWVL 618
Query: 70 TAAHCISSS---GIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGNDIALLK 126
TAAHC+ S Y+V+LG H E + VS++ + DIALLK
Sbjct: 619 TAAHCLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPT--------RKDIALLK 670
Query: 127 LANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQ-TNGALPDDLKQGRLLVVDYAT 185
L++P +TDK+ ACLP ++ + C++TGWG Q T GA LK+ +L V++
Sbjct: 671 LSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFGA--GLLKEAQLPVIENKV 728
Query: 186 CSSSGWWGSTVKTNMICAGG-DGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSVLGCN 244
C+ + V++ +CAG G +C GDSGGPL C D ++ + G+ S LGC
Sbjct: 729 CNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKD-KYILQGVTSWG--LGCA 785
Query: 245 YYYKPSIFTRVSNYNDWINSVIANN 269
KP ++ RVS + WI V+ NN
Sbjct: 786 RPNKPGVYVRVSRFVTWIEGVMRNN 810
>gi|117956391 protease, serine, 33 [Homo sapiens]
Length = 280
Score = 153 bits (386), Expect = 2e-37
Identities = 95/254 (37%), Positives = 132/254 (51%), Gaps = 22/254 (8%)
Query: 27 SRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAHCISSSGI---YRV 83
SR++GG + R WPWQ S+Q+ H CGGSLIA WVLTAAHC + YRV
Sbjct: 35 SRIVGGRDGRDGEWPWQASIQHRGA----HVCGGSLIAPQWVLTAAHCFPRRALPAEYRV 90
Query: 84 MLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGNDIALLKLANPVSLTDKIQLACLP 143
LG L +L+V V ++++ D++ D D+ALL+L PV L+ ++Q CLP
Sbjct: 91 RLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGAR--GDLALLQLRRPVPLSARVQPVCLP 148
Query: 144 PAGTILPNNYPCYVTGWGRLQTNGALPD--DLKQGRLLVVDYATCSSSGWWGSTVK---- 197
G P PC VTGWG L+ LP+ L+ R+ ++D TC G+ V
Sbjct: 149 VPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQAER 208
Query: 198 ---TNMICAG-GDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSVLGCNYYYKPSIFT 253
+CAG G C GDSGGPL C S G W + G+ S GC +P ++T
Sbjct: 209 IVLPGSLCAGYPQGHKDACQGDSGGPLTCLQS-GSWVLVGVVSWGK--GCALPNRPGVYT 265
Query: 254 RVSNYNDWINSVIA 267
V+ Y+ WI + ++
Sbjct: 266 SVATYSPWIQARVS 279
>gi|29244926 corin [Homo sapiens]
Length = 1042
Score = 148 bits (373), Expect = 6e-36
Identities = 92/263 (34%), Positives = 140/263 (53%), Gaps = 15/263 (5%)
Query: 9 TLVAGALSCGVSTYAPDMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANSWV 68
+L+ CG A R+LGG +RP WPWQ SLQ +G H CG LIA WV
Sbjct: 782 SLLCTKQDCGRRPAARMNKRILGGRTSRPGRWPWQCSLQSEPSG---HICGCVLIAKKWV 838
Query: 69 LTAAHCIS---SSGIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGNDIALL 125
LT AHC ++ +++V+LG +NL V I++H ++ V DI+++
Sbjct: 839 LTVAHCFEGRENAAVWKVVLGINNLDHPSVFMQTRFVKTIILHPRYSRAVVDY--DISIV 896
Query: 126 KLANPVSLTDKIQLACLP-PAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRLLVVDYA 184
+L+ +S T ++ CLP P + P+ Y CY+TGWG + +P L++G + ++
Sbjct: 897 ELSEDISETGYVRPVCLPNPEQWLEPDTY-CYITGWGHM--GNKMPFKLQEGEVRIISLE 953
Query: 185 TCSSSGWWGSTVKTNMICAGGD-GVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSVLGC 243
C S + T+ T MICAG + G + +C GDSGGPL C+ GRW + G+ S SV
Sbjct: 954 HCQSY-FDMKTITTRMICAGYESGTVDSCMGDSGGPLVCEKPGGRWTLFGLTSWGSVC-F 1011
Query: 244 NYYYKPSIFTRVSNYNDWINSVI 266
+ P +++ VS + +WI I
Sbjct: 1012 SKVLGPGVYSNVSYFVEWIKRQI 1034
>gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo
sapiens]
Length = 432
Score = 147 bits (372), Expect = 7e-36
Identities = 95/257 (36%), Positives = 140/257 (54%), Gaps = 24/257 (9%)
Query: 15 LSCGVSTYAPDMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAHC 74
L+CG S P R++GGEEA +SWPWQVS+QY H CGGS++ WVLTAAHC
Sbjct: 189 LACGKSLKTP---RVVGGEEASVDSWPWQVSIQYDKQ----HVCGGSILDPHWVLTAAHC 241
Query: 75 ISSSGI---YRVMLGQHNLYVAESGSL-AVSVSKIVVHKDWNSDQVSKGNDIALLKLANP 130
++V G L GS +++V+KI++ + + K NDIAL+KL P
Sbjct: 242 FRKHTDVFNWKVRAGSDKL-----GSFPSLAVAKIIIIEF--NPMYPKDNDIALMKLQFP 294
Query: 131 VSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGA-LPDDLKQGRLLVVDYATCSSS 189
++ + ++ CLP L P ++ GWG + NG + D L Q + V+D C++
Sbjct: 295 LTFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNAD 354
Query: 190 GWWGSTVKTNMICAG-GDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSVLGCNYYYK 248
+ V M+CAG +G + TC GDSGGPL Q+ +W H +G ++ GC
Sbjct: 355 DAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSD--QW--HVVGIVSWGYGCGGPST 410
Query: 249 PSIFTRVSNYNDWINSV 265
P ++T+VS Y +WI +V
Sbjct: 411 PGVYTKVSAYLNWIYNV 427
>gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo
sapiens]
Length = 437
Score = 147 bits (372), Expect = 7e-36
Identities = 95/257 (36%), Positives = 140/257 (54%), Gaps = 24/257 (9%)
Query: 15 LSCGVSTYAPDMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAHC 74
L+CG S P R++GGEEA +SWPWQVS+QY H CGGS++ WVLTAAHC
Sbjct: 194 LACGKSLKTP---RVVGGEEASVDSWPWQVSIQYDKQ----HVCGGSILDPHWVLTAAHC 246
Query: 75 ISSSGI---YRVMLGQHNLYVAESGSL-AVSVSKIVVHKDWNSDQVSKGNDIALLKLANP 130
++V G L GS +++V+KI++ + + K NDIAL+KL P
Sbjct: 247 FRKHTDVFNWKVRAGSDKL-----GSFPSLAVAKIIIIEF--NPMYPKDNDIALMKLQFP 299
Query: 131 VSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGA-LPDDLKQGRLLVVDYATCSSS 189
++ + ++ CLP L P ++ GWG + NG + D L Q + V+D C++
Sbjct: 300 LTFSGTVRPICLPFFDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNAD 359
Query: 190 GWWGSTVKTNMICAG-GDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSVLGCNYYYK 248
+ V M+CAG +G + TC GDSGGPL Q+ +W H +G ++ GC
Sbjct: 360 DAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMYQSD--QW--HVVGIVSWGYGCGGPST 415
Query: 249 PSIFTRVSNYNDWINSV 265
P ++T+VS Y +WI +V
Sbjct: 416 PGVYTKVSAYLNWIYNV 432
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 147 bits (372), Expect = 7e-36
Identities = 85/252 (33%), Positives = 134/252 (53%), Gaps = 36/252 (14%)
Query: 27 SRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAHCISSSGIYRVMLG 86
SR++GG + + WPWQ SLQ+ Q YH CGGS+I W++TAAHC+
Sbjct: 215 SRIVGGNMSLLSQWPWQASLQF----QGYHLCGGSVITPLWIITAAHCV----------- 259
Query: 87 QHNLYVAESGSLAVS-------------VSKIVVHKDWNSDQVSKGNDIALLKLANPVSL 133
++LY+ +S ++ V V KIV H + ++ GNDIAL+KLA P++
Sbjct: 260 -YDLYLPKSWTIQVGLVSLLDNPAPSHLVEKIVYHSKYKPKRL--GNDIALMKLAGPLTF 316
Query: 134 TDKIQLACLPPAGTILPNNYPCYVTGWGRLQTN-GALPDDLKQGRLLVVDYATCSSSGWW 192
+ IQ CLP + P+ C+ +GWG + G L + ++ C+ +
Sbjct: 317 NEMIQPVCLPNSEENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVY 376
Query: 193 GSTVKTNMICAGG-DGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSVLGCNYYYKPSI 251
G + +M+CAG G + +C GDSGGPL CQ W++ +G+ + +GC KP +
Sbjct: 377 GGIISPSMLCAGYLTGGVDSCQGDSGGPLVCQ-ERRLWKL--VGATSFGIGCAEVNKPGV 433
Query: 252 FTRVSNYNDWIN 263
+TRV+++ DWI+
Sbjct: 434 YTRVTSFLDWIH 445
>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
Length = 321
Score = 147 bits (370), Expect = 1e-35
Identities = 100/263 (38%), Positives = 138/263 (52%), Gaps = 23/263 (8%)
Query: 7 LSTLVAGALSCGVSTYAPDMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANS 66
L TL G CG + R++GG A +WPWQ SL+ H CGGSL++
Sbjct: 19 LRTLQPG---CGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRR----VHVCGGSLLSPQ 71
Query: 67 WVLTAAHCIS---SSGIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGNDIA 123
WVLTAAHC S +S Y+V LG+ + ++ S +V +I++H S Q DIA
Sbjct: 72 WVLTAAHCFSGSLNSSDYQVHLGELEITLSPHFS---TVRQIILHSS-PSGQPGTSGDIA 127
Query: 124 LLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPD--DLKQGRLLVV 181
L++L+ PV+L+ +I CLP A C+VTGWG + LP L++ ++ VV
Sbjct: 128 LVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLREVKVSVV 187
Query: 182 DYATCSSS--GWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTS 239
D TC G GS ++ +M+CA G G C DSGGPL CQ +G W GI S
Sbjct: 188 DTETCRRDYPGPGGSILQPDMLCARGPG--DACQDDSGGPLVCQV-NGAWVQAGIVSWGE 244
Query: 240 VLGCNYYYKPSIFTRVSNYNDWI 262
GC +P ++TRV Y +WI
Sbjct: 245 --GCGRPNRPGVYTRVPAYVNWI 265
>gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]
Length = 2040
Score = 144 bits (363), Expect = 8e-35
Identities = 94/264 (35%), Positives = 134/264 (50%), Gaps = 30/264 (11%)
Query: 12 AGALSCGVSTYAPDM--SRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANSWVL 69
+ + CG P ++GG A P+SWPWQVSL+ H CGG+LI+ WVL
Sbjct: 1801 SSSFDCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRFGK---HFCGGTLISPEWVL 1857
Query: 70 TAAHCISSSG---IYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGNDIALLK 126
TAAHC+ S Y+V+LG H ES + VS++ + DIALLK
Sbjct: 1858 TAAHCLKKSSRPSSYKVILGAHQEVNLESHVQEIEVSRLFLEPTQA--------DIALLK 1909
Query: 127 LANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDD-LKQGRLLVVDYAT 185
L+ P +TDK+ ACLP ++ CY+TGWG +T G LK+ +LLV++
Sbjct: 1910 LSRPAVITDKVMPACLPSPDYMVTARTECYITGWG--ETQGTFGTGLLKEAQLLVIENEV 1967
Query: 186 CSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSVLGCNY 245
C+ + + + G D +C GDSGGPL C D ++ + G+ S LGC
Sbjct: 1968 CNHYKY----ICAEHLARGTD----SCQGDSGGPLVCFEKD-KYILQGVTSWG--LGCAR 2016
Query: 246 YYKPSIFTRVSNYNDWINSVIANN 269
KP ++ RVS + WI ++ NN
Sbjct: 2017 PNKPGVYARVSRFVTWIEGMMRNN 2040
>gi|4506153 prostasin preproprotein [Homo sapiens]
Length = 343
Score = 144 bits (362), Expect = 1e-34
Identities = 92/262 (35%), Positives = 130/262 (49%), Gaps = 25/262 (9%)
Query: 17 CGVSTYAPDMSRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAHCIS 76
CGV+ A R+ GG A WPWQVS+ Y H CGGSL++ WVL+AAHC
Sbjct: 37 CGVAPQA----RITGGSSAVAGQWPWQVSITYEG----VHVCGGSLVSEQWVLSAAHCFP 88
Query: 77 SSG---IYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGNDIALLKLANPVSL 133
S Y V LG H L + ++ I+ H + Q DIALL+L+ P++
Sbjct: 89 SEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYL--QEGSQGDIALLQLSRPITF 146
Query: 134 TDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAL--PDDLKQGRLLVVDYATCS---- 187
+ I+ CLP A PN C VTGWG + + +L P L+Q + ++ TC+
Sbjct: 147 SRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYN 206
Query: 188 --SSGWWGSTVKTNMICAG-GDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSVLGCN 244
+ V+ +M+CAG +G C GDSGGPL+C +G W + GI S C
Sbjct: 207 IDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPV-EGLWYLTGIVSWGD--ACG 263
Query: 245 YYYKPSIFTRVSNYNDWINSVI 266
+P ++T S+Y WI S +
Sbjct: 264 ARNRPGVYTLASSYASWIQSKV 285
>gi|187761337 transmembrane protease, serine 11B [Homo sapiens]
Length = 416
Score = 143 bits (360), Expect = 2e-34
Identities = 86/242 (35%), Positives = 129/242 (53%), Gaps = 16/242 (6%)
Query: 27 SRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAHCIS---SSGIYRV 83
++++ G+ + +WPWQ S+Q+ H CG SLI++ W+L+AAHC + +S + V
Sbjct: 183 NKIVNGKSSLEGAWPWQASMQWKGR----HYCGASLISSRWLLSAAHCFAKKNNSKDWTV 238
Query: 84 MLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGNDIALLKLANPVSLTDKIQLACLP 143
G V + V I+ H++++S + +DIAL++LA VS T+ I+ CLP
Sbjct: 239 NFG----IVVNKPYMTRKVQNIIFHENYSSPGLH--DDIALVQLAEEVSFTEYIRKICLP 292
Query: 144 PAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRLLVVDYATCSSSGWWGSTVKTNMICA 203
A L N VTGWG L NG+ P L++ L ++D C++S + V M+CA
Sbjct: 293 EAKMKLSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAYSGFVTDTMLCA 352
Query: 204 G-GDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSVLGCNYYYKPSIFTRVSNYNDWI 262
G G C DSGGPL S W + GI S GC KP ++TRV++Y +WI
Sbjct: 353 GFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGD--GCGKKNKPGVYTRVTSYRNWI 410
Query: 263 NS 264
S
Sbjct: 411 TS 412
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 142 bits (359), Expect = 2e-34
Identities = 87/241 (36%), Positives = 130/241 (53%), Gaps = 13/241 (5%)
Query: 27 SRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAHCISS---SGIYRV 83
+R++GG + WPWQVSLQ Q H CGGSLI + WVLTAAHC ++R+
Sbjct: 389 TRIVGGTNSSWGEWPWQVSLQVKLTAQ-RHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRI 447
Query: 84 MLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGN-DIALLKLANPVSLTDKIQLACL 142
G NL + + +I++H+++ +VS+GN DIAL+KL P++ T+ + CL
Sbjct: 448 YSGILNLSDITKDTPFSQIKEIIIHQNY---KVSEGNHDIALIKLQAPLNYTEFQKPICL 504
Query: 143 PPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGRLLVVDYATCSSSGWWGSTVKTNMIC 202
P G C+VTGWG + G + + L++ + +V C + + M+C
Sbjct: 505 PSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKR-YQDYKITQRMVC 563
Query: 203 AG-GDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSVLGCNYYYKPSIFTRVSNYNDW 261
AG +G C GDSGGPL C+ +G W + GI S GC +P ++T+V+ Y DW
Sbjct: 564 AGYKEGGKDACKGDSGGPLVCK-HNGMWRLVGITSWGE--GCARREQPGVYTKVAEYMDW 620
Query: 262 I 262
I
Sbjct: 621 I 621
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.433
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,788,940
Number of Sequences: 37866
Number of extensions: 475211
Number of successful extensions: 1822
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 170
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1048
Number of HSP's gapped (non-prelim): 223
length of query: 269
length of database: 18,247,518
effective HSP length: 101
effective length of query: 168
effective length of database: 14,423,052
effective search space: 2423072736
effective search space used: 2423072736
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.