BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|58331177 ermin, ERM-like protein isoform a [Homo sapiens] (297 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|58331177 ermin, ERM-like protein isoform a [Homo sapiens] 602 e-172 gi|58331175 ermin, ERM-like protein isoform b [Homo sapiens] 576 e-164 gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 50 2e-06 gi|21396500 HIRA interacting protein 3 [Homo sapiens] 50 2e-06 gi|4505257 moesin [Homo sapiens] 46 3e-05 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 46 5e-05 gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 45 6e-05 gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 45 1e-04 gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 45 1e-04 gi|217330641 IWS1 homolog [Homo sapiens] 44 1e-04 gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H... 44 2e-04 gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 44 2e-04 gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 44 2e-04 gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 44 2e-04 gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 44 2e-04 gi|4506467 radixin [Homo sapiens] 44 2e-04 gi|4504487 histidine rich calcium binding protein precursor [Hom... 44 2e-04 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 43 3e-04 gi|115529449 upstream binding transcription factor, RNA polymera... 43 3e-04 gi|115529451 upstream binding transcription factor, RNA polymera... 43 3e-04 gi|7657671 upstream binding transcription factor, RNA polymerase... 43 3e-04 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 42 5e-04 gi|161702986 ezrin [Homo sapiens] 42 7e-04 gi|21614499 ezrin [Homo sapiens] 42 7e-04 gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 42 7e-04 gi|55956788 nucleolin [Homo sapiens] 41 0.001 gi|55741677 SET domain containing 1A [Homo sapiens] 41 0.001 gi|210032580 SET domain containing 1B [Homo sapiens] 41 0.001 gi|9257192 adducin 2 isoform a [Homo sapiens] 40 0.002 gi|60498973 myelin transcription factor 1-like [Homo sapiens] 40 0.002 >gi|58331177 ermin, ERM-like protein isoform a [Homo sapiens] Length = 297 Score = 602 bits (1553), Expect = e-172 Identities = 297/297 (100%), Positives = 297/297 (100%) Query: 1 MKTLSPDRIQPHIMTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEP 60 MKTLSPDRIQPHIMTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEP Sbjct: 1 MKTLSPDRIQPHIMTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEP 60 Query: 61 SLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEM 120 SLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEM Sbjct: 61 SLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEM 120 Query: 121 TFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQ 180 TFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQ Sbjct: 121 TFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQ 180 Query: 181 ADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSP 240 ADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSP Sbjct: 181 ADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSP 240 Query: 241 LSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL 297 LSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL Sbjct: 241 LSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL 297 >gi|58331175 ermin, ERM-like protein isoform b [Homo sapiens] Length = 284 Score = 576 bits (1484), Expect = e-164 Identities = 284/284 (100%), Positives = 284/284 (100%) Query: 14 MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEE 73 MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEE Sbjct: 1 MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEE 60 Query: 74 RRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPL 133 RRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPL Sbjct: 61 RRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPL 120 Query: 134 SGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQK 193 SGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQK Sbjct: 121 SGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQK 180 Query: 194 VWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDE 253 VWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDE Sbjct: 181 VWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDE 240 Query: 254 QPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL 297 QPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL Sbjct: 241 QPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL 284 >gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] Length = 238 Score = 50.4 bits (119), Expect = 2e-06 Identities = 43/194 (22%), Positives = 89/194 (45%), Gaps = 16/194 (8%) Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130 +E +K++ + E+KM +E E+ K + ++M +E WE+ Sbjct: 8 REREKKMREEEEMMREQEEKM-QEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 66 Query: 131 IPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSK--- 187 Q + QKE++ EQ + E E+R + ++E + +K +Q + + + Sbjct: 67 EEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEK 126 Query: 188 -HDEEQKVWD-EEIDDDDDDNCNNDEDEVRVIEFK-KKHEEVSQFKEE---------GDA 235 ++E+ +W+ EE + ++ E+++R E K ++ EE Q +EE G+A Sbjct: 127 MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEA 186 Query: 236 SEDSPLSSASSQAV 249 E SP + ++Q + Sbjct: 187 GEGSPQDNPTAQEI 200 Score = 28.1 bits (61), Expect = 9.7 Identities = 14/61 (22%), Positives = 33/61 (54%), Gaps = 2/61 (3%) Query: 138 QEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDE 197 +E R +ER E+ ++EEE+ R+ + + E + ++ + ++E+K+W++ Sbjct: 2 REEERMRER--EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59 Query: 198 E 198 E Sbjct: 60 E 60 >gi|21396500 HIRA interacting protein 3 [Homo sapiens] Length = 556 Score = 50.1 bits (118), Expect = 2e-06 Identities = 63/304 (20%), Positives = 121/304 (39%), Gaps = 37/304 (12%) Query: 5 SPDRIQPHIMTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEG 64 SPD P V A + A+ ++ P + + + S+E D P E Sbjct: 108 SPDYFGPPAKNGVAAEVSPAK---EENPRRASKAVEESSDEERQRDLPAQRGEESSEEEE 164 Query: 65 ALTKGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFRE 124 KG ++ ++ +S+ K +E EE ++ + +A ++ + Sbjct: 165 KGYKGKTRKKPVVKKQAPGKASVSRKQAREESEE---------SEAEPVQRTAKKVEGNK 215 Query: 125 GHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQAD-M 183 G + K S +EI QK+ E+ ++EEE E+ + KG G RK ++ + Sbjct: 216 GTKSLKESEQESEEEILAQKKEQREEEVEEEEKEEDEEKGDWKPRTRSNGRRKSAREERS 275 Query: 184 LHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIE--FKKKHEEVSQFK----------E 231 K ++ + D + +++ + ++ +D R E ++K E+ +Q K + Sbjct: 276 CKQKSQAKRLLGDSDSEEEQKEAASSGDDSGRDREPPVQRKSEDRTQLKGGKRLSGSSED 335 Query: 232 EGDASEDSPLSSASSQAVTPDEQPTLGKKSDISRNAY----------SRYNTISYRKIRK 281 E D+ + P + S + T G++SD+ R R N S + RK Sbjct: 336 EEDSGKGEPTAKGSRKMARLGS--TSGEESDLEREVSDSEAGGGPQGERKNRSSKKSSRK 393 Query: 282 GNTK 285 G T+ Sbjct: 394 GRTR 397 >gi|4505257 moesin [Homo sapiens] Length = 577 Score = 46.2 bits (108), Expect = 3e-05 Identities = 63/272 (23%), Positives = 113/272 (41%), Gaps = 23/272 (8%) Query: 27 NGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERR--KLQGNMLLN 84 N K E ++ KI E ++ L ++E + A + ++ RR +L+ Sbjct: 325 NEKKKREMAEKEKEKIEREKEELMERLK--QIEEQTKKAQQELEEQTRRALELEQERKRA 382 Query: 85 SSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSG--SNQEIRR 142 S +K+ KE E + +L + S D+ +E E L+ S E+ R Sbjct: 383 QSEAEKLAKERQEAEE-------AKEALLQASRDQKKTQEQLALEMAELTARISQLEMAR 435 Query: 143 QKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDD 202 QK+ +++ +++ AE++ P A+ ++ DE+ + E D Sbjct: 436 QKKESEAVEWQQKAQMVQEDLEKTRAELK-TAMSTPHVAEPAENEQDEQDENGAEASADL 494 Query: 203 DDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSD 262 D D E +K+E V + + + S L++A ++ + Sbjct: 495 RADAMAKDRSEEERTTEAEKNERVQKHLK----ALTSELANARDESKKTANDMIHAENMR 550 Query: 263 ISRNAYSRYNTISYRKIRKGNTKQRIDEFESM 294 + R+ Y + R+IR+GNTKQRIDEFESM Sbjct: 551 LGRDKYK-----TLRQIRQGNTKQRIDEFESM 577 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 45.8 bits (107), Expect = 5e-05 Identities = 44/199 (22%), Positives = 87/199 (43%), Gaps = 16/199 (8%) Query: 71 QEER-RKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLS-LQETSADEMTFREGHQW 128 Q+ER R+ + M M ++ K EE++ K + + ++M +E + W Sbjct: 364 QDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMW 423 Query: 129 EKIPLSGSNQEIRRQKERITEQPLKEEEDE---DRKNKGHQAAEI------EWLGFRKPS 179 E+ Q + QKE++ EQ +E++E +++ K E+ W + Sbjct: 424 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 483 Query: 180 QADML----HSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDA 235 Q D + D+EQK+WD+E + D +++E R+ E KK ++ + +EE Sbjct: 484 QEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEE-RMREQKKMWQQEEKMREEKKT 542 Query: 236 SEDSPLSSASSQAVTPDEQ 254 E + + + +E+ Sbjct: 543 QEQEKKTWDQEEKMREEER 561 Score = 39.7 bits (91), Expect = 0.003 Identities = 43/215 (20%), Positives = 87/215 (40%), Gaps = 33/215 (15%) Query: 73 ERRKLQGNMLLNSSMEDKMLKENP-----EEKLFIVHKAITDLSLQETSADE-MTFREGH 126 E++KL+ E+KM ++ EEK++ + + + Q ++ M +E Sbjct: 301 EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 360 Query: 127 QWEKIPLSGSNQEIRRQKERITEQPLKEEEDE---DRKNKGHQAAEI------------- 170 WE+ +E R++E++ EQ K +E+E +R+ K + E Sbjct: 361 MWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 420 Query: 171 --------EWLGFRKPSQADML---HSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEF 219 EW R P Q + L ++E+K+W++E D + E ++ E Sbjct: 421 NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEK 480 Query: 220 KKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQ 254 ++ E+ +EE ++ + + DE+ Sbjct: 481 MREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDER 515 Score = 34.3 bits (77), Expect = 0.14 Identities = 26/151 (17%), Positives = 67/151 (44%), Gaps = 4/151 (2%) Query: 113 QETSADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEW 172 +E E + Q EK+ +E R +K R E+ ++E+E++ ++ + + E Sbjct: 538 EEKKTQEQEKKTWDQEEKMREEERMRE-REKKMREEEEMMREQEEKMQEQEEKMREQEEK 596 Query: 173 LGFRKPSQADMLHSKHDEEQKVWDEEIDD---DDDDNCNNDEDEVRVIEFKKKHEEVSQF 229 + ++ + ++E+K+W++E +D + ++ E++++ E K +E Sbjct: 597 MWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR 656 Query: 230 KEEGDASEDSPLSSASSQAVTPDEQPTLGKK 260 ++E E + + E+ G++ Sbjct: 657 EQEEKMREQEEKMQGQEEKMREQEEKMQGQE 687 Score = 33.5 bits (75), Expect = 0.23 Identities = 51/224 (22%), Positives = 95/224 (42%), Gaps = 36/224 (16%) Query: 36 QQTITKISEELTDVDSPLPH-YRVEPSLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKE 94 + TIT +EEL ++ L R+ S + + +E +RKL+ L ++ L+E Sbjct: 177 RNTIT--NEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQE 234 Query: 95 N---PEEKLFIVHKAITD----LSLQETSADEMTFREGHQWEKIP-----LSGSNQEIRR 142 EE+L K I + QE E + Q EK+ L +E+R Sbjct: 235 EMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELRE 294 Query: 143 QKERITEQP-LKEEEDE---------DRKNKGHQAAEIEW-----LGFRKPSQADMLHSK 187 Q++ + EQ L+E+E++ +++ K + E W L ++ + Sbjct: 295 QEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKM 354 Query: 188 HDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKE 231 D+E+++W++ D+ E+ +R E + EE Q +E Sbjct: 355 RDQEERMWEQ------DERLREKEERMREQEKMWEQEEKMQEEE 392 Score = 32.3 bits (72), Expect = 0.52 Identities = 30/161 (18%), Positives = 69/161 (42%), Gaps = 22/161 (13%) Query: 72 EERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKI 131 E+ K+Q E+KM ++ E+K+ + + + ++M +E WE+ Sbjct: 599 EQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWE------QEEKMQEQEEKMWEQ- 651 Query: 132 PLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEE 191 +++R Q+E++ EQ K + E++ + + + + R+ + +E Sbjct: 652 -----EEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEE-----KMRGQE 701 Query: 192 QKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEE 232 +K+W +E + +E E ++K E + KE+ Sbjct: 702 EKMWGQE-----EKMWGQEEKMWGQEEMREKEERIRDQKEK 737 Score = 30.8 bits (68), Expect = 1.5 Identities = 29/165 (17%), Positives = 77/165 (46%), Gaps = 13/165 (7%) Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130 QE+ R+ + M E+KM + E+K++ + + + + +E + W++ Sbjct: 478 QEKMREQEDQMW---EQEEKM--RDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQ 532 Query: 131 IPLSGSNQEIRRQKERITEQPLKEEEDE---DRKNKGHQAAEIEWLGFRKPSQADMLHSK 187 ++ + Q+++ +Q K E+E +R+ K + E E + ++ + Sbjct: 533 EEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMRE--EEEMMREQEEKMQEQEEKM 590 Query: 188 HDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEE 232 ++E+K+W++E + + +++E ++++ E+ Q +EE Sbjct: 591 REQEEKMWEQEEKMQEQEEKMWEQEEKM---WEQEEEDKMQEQEE 632 >gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens] Length = 570 Score = 45.4 bits (106), Expect = 6e-05 Identities = 59/296 (19%), Positives = 127/296 (42%), Gaps = 42/296 (14%) Query: 36 QQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERRKLQGNM-------LLNSSME 88 Q + ++ +L LP +++ + L K Q KLQ + LN E Sbjct: 229 QLNVKELKRKLERAKLLLPQQQLQAEADH-LGKELQSVSAKLQAQVEENELWNRLNQQQE 287 Query: 89 DKMLKENP-----EEKLFIVHKAITDLSLQETSADEMTF--------REGHQWEKIPLSG 135 +KM ++ EEK+ + I + + +EM + +E WEK Sbjct: 288 EKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 347 Query: 136 SNQEIRRQKERITEQPLKEEEDE---DRKNKGHQAAEIEWLGFRK--------PSQADML 184 +E ++E+I EQ K +E+E +++ + Q A++ W K Q +M+ Sbjct: 348 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM-WRQEEKIREQEEKIREQEEMM 406 Query: 185 HSKH----DEEQKVWDEEID-DDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDS 239 + ++E+K+W++E + + ++ E+++R E KK E+ + +E+ + ++ Sbjct: 407 QEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQE-KKIREQEEKIREQEEMMQEQ 465 Query: 240 PLSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMM 295 + +++ + ++ + R + +KIR+ +++I E E MM Sbjct: 466 EEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIRE-QEKKIRE--QEEKIREQEEMM 518 Score = 40.4 bits (93), Expect = 0.002 Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 33/179 (18%) Query: 69 GSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITD----LSLQETSADEMTFRE 124 G QEE+ Q + E+KM ++ EEK+ K I + + QE E + Sbjct: 414 GEQEEKMWEQEEEM--QEQEEKMRRQ--EEKIREQEKKIREQEEKIREQEEMMQEQEEKM 469 Query: 125 GHQWEKI-----PLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPS 179 G Q K+ + +++RRQ+E+I EQ K E E++ + Sbjct: 470 GEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIRE---------------- 513 Query: 180 QADMLHSKHDEEQKVWD-EEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASE 237 Q +M+ ++E+K+W+ EE + ++ E+++R E K + +EV ++E E Sbjct: 514 QEEMMQ---EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569 Score = 34.3 bits (77), Expect = 0.14 Identities = 36/165 (21%), Positives = 75/165 (45%), Gaps = 6/165 (3%) Query: 71 QEERRKLQGNMLLNSSMEDKMLKE-NPEEKLFIVHKAITDLSLQETSADEMTFREGHQWE 129 QEE+R+ + + +++ K EEK+ + I + QE E + G Q E Sbjct: 362 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE---QEEMMQEQEEKMGEQEE 418 Query: 130 KIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHD 189 K+ + + +K R E+ ++E+E + R+ + + E + ++ + + Sbjct: 419 KMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCE 478 Query: 190 EEQKVWD-EEIDDDDDDNCNNDEDEVRVIEFK-KKHEEVSQFKEE 232 +E K+ + EE ++ E ++R E K ++ EE+ Q +EE Sbjct: 479 QEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 523 >gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 750 Score = 44.7 bits (104), Expect = 1e-04 Identities = 39/175 (22%), Positives = 80/175 (45%), Gaps = 11/175 (6%) Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSA----DEMTFREGH 126 QEE+ + Q + E KM ++ EEK+ K + QE +E + Sbjct: 435 QEEKIREQEEKI--REQEKKMWRQ--EEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEE 490 Query: 127 QW-EKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLH 185 W +K + ++IR+Q+E++ Q K E E++ + + + R+ + Sbjct: 491 IWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREE 550 Query: 186 SKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFK--KKHEEVSQFKEEGDASED 238 K E++K+W+EE + +D E+++R E K ++ E++ + +E+ E+ Sbjct: 551 EKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEE 605 Score = 41.6 bits (96), Expect = 8e-04 Identities = 40/187 (21%), Positives = 83/187 (44%), Gaps = 19/187 (10%) Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130 +EE+R+ Q EDKM ++ EEK + + + QE E + Q EK Sbjct: 561 EEEKRQEQ---------EDKMWRQ--EEK---IREQEEKVWRQEEKIREQEEKRQEQEEK 606 Query: 131 IPLSGSNQEIRRQKERITEQP--LKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKH 188 + ++IR Q+E+I EQ ++E+E++ R+ + + E +G ++ + Sbjct: 607 --MWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQ 664 Query: 189 DEEQKVW-DEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQ 247 ++E+ +W EE + + E+++R E + +E +++E E + Sbjct: 665 EQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 724 Query: 248 AVTPDEQ 254 + E+ Sbjct: 725 KMRRQEE 731 Score = 41.2 bits (95), Expect = 0.001 Identities = 41/211 (19%), Positives = 102/211 (48%), Gaps = 17/211 (8%) Query: 88 EDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKERI 147 E+K+ K+ EEK++ + I + + +E +R+ + + +E ++E+I Sbjct: 502 EEKIRKQ--EEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKI 559 Query: 148 TEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQA-DMLHSKHDEEQKVW-DEEIDDDDDD 205 E+ ++E+++ + + E E +R+ + + + ++E+K+W EE + ++ Sbjct: 560 WEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEE 619 Query: 206 NCNNDEDEVRVIEFK-KKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSDIS 264 E+++R E K ++ EE++Q +EE ++ + + +++ T+ ++ + Sbjct: 620 KIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKM--CEQEEKMQEQEETMWRQEEKI 677 Query: 265 RNAYSRYNTISYRKIRKGNTKQRIDEFESMM 295 R +KIR+ +++I E E MM Sbjct: 678 RE--------QEKKIRE--QEEKIREQEEMM 698 Score = 40.0 bits (92), Expect = 0.002 Identities = 37/198 (18%), Positives = 95/198 (47%), Gaps = 17/198 (8%) Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130 +EE+R+ Q M E+K+ + +E+++ + + + + +E +R Q EK Sbjct: 468 EEEKRQEQEEMW---RQEEKI---HEQEEIWRQKEKMHEQEEKIRKQEEKVWR---QEEK 518 Query: 131 IPLSGSNQEIRRQKERI--TEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKH 188 I ++IR Q+E++ E+ ++E+E+ R+ + E W ++ Q D + + Sbjct: 519 I--REQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE 576 Query: 189 D----EEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSA 244 + +E+KVW +E + + +++E + +K E+ + +E+ + + Sbjct: 577 EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIR 636 Query: 245 SSQAVTPDEQPTLGKKSD 262 + +T +++ +G++ + Sbjct: 637 EQEEMTQEQEEKMGEQEE 654 Score = 39.3 bits (90), Expect = 0.004 Identities = 51/272 (18%), Positives = 112/272 (41%), Gaps = 31/272 (11%) Query: 36 QQTITKISEELTDVDSPL-PHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKE 94 Q + ++ E D+ S L ++ LE AL+ + ++++ +++ KE Sbjct: 150 QHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKA--------DRYIEELTKE 201 Query: 95 NPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKER----ITEQ 150 L + ITD L+E +A + + EK + + +E++R+ ER + +Q Sbjct: 202 RDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQ 261 Query: 151 PLKEEEDEDRKNKGHQAAEIEW------LGFRKPSQADMLHSKHDEEQKVWDEEIDDDDD 204 L+ E D K +A+++ L R Q + + +E+ + W+E+I + + Sbjct: 262 QLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQ-EQE 320 Query: 205 DNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSDIS 264 + E+++R E K + +E +++E + + + E+ K+ + Sbjct: 321 EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 380 Query: 265 RNAYSRYNTISYRKIRKGNTKQRIDEFESMMH 296 R + +++I E E MH Sbjct: 381 RQEEMMW-----------EKEEKIRELEEKMH 401 Score = 38.9 bits (89), Expect = 0.006 Identities = 37/190 (19%), Positives = 82/190 (43%), Gaps = 24/190 (12%) Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130 +EE+ + Q M+ + + L+E E+ + I + + +++ +E Q ++ Sbjct: 375 KEEKMRRQEEMMWEKEEKIRELEEKMHEQ-----EKIREQEEKRQEEEKIREQEKRQEQE 429 Query: 131 IPLSGSNQEIRRQKERITEQPLK--------EEEDEDRKNKGHQAAEIEWLGFRKPS--- 179 + ++IR Q+E+I EQ K E+++ R+ + Q E W K Sbjct: 430 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQE 489 Query: 180 ----QADMLHSKHD----EEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKE 231 Q + +H + + +E+KVW +E + + +++E + +K E+ ++E Sbjct: 490 EIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWRE 549 Query: 232 EGDASEDSPL 241 E E + Sbjct: 550 EEKMHEQEKI 559 Score = 38.1 bits (87), Expect = 0.009 Identities = 38/173 (21%), Positives = 75/173 (43%), Gaps = 25/173 (14%) Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130 QEE+R+ Q + + + +E +E+ + + + QE E + G Q EK Sbjct: 596 QEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655 Query: 131 I-----PLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLH 185 + + + + RQ+E+I EQ K E E++ + Q +M+ Sbjct: 656 MCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIRE----------------QEEMMQ 699 Query: 186 SKHDEEQKVWD-EEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASE 237 ++E+K+W+ EE + ++ E+++R E K +EV ++E E Sbjct: 700 ---EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749 >gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 436 Score = 44.7 bits (104), Expect = 1e-04 Identities = 37/193 (19%), Positives = 88/193 (45%), Gaps = 13/193 (6%) Query: 69 GSQEERRKLQGNMLLNSSMEDKMLKENP-----EEKLFIVHKAITDLSLQETSADEMTFR 123 G QEE+ + Q + E+++ K+ EE++ + + + Q +E + Sbjct: 223 GEQEEQMRKQEEQM--GEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLK 280 Query: 124 EGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADM 183 + Q E+ +G +E R++E + ++E+E++ R+ + + E +G ++ + Sbjct: 281 QKEQTEQEEQTGEQEEQMREQE----EQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQ 336 Query: 184 LHSKHDEEQKVW-DEEIDDDDDDNCNNDEDEVRVIEFK-KKHEEVSQFKEEGDASEDSPL 241 ++++++W EE + ++ E++VR E + +K EE + +EE ++ + Sbjct: 337 KEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQM 396 Query: 242 SSASSQAVTPDEQ 254 Q EQ Sbjct: 397 GEQKEQMGEQKEQ 409 Score = 32.0 bits (71), Expect = 0.67 Identities = 23/143 (16%), Positives = 62/143 (43%), Gaps = 1/143 (0%) Query: 113 QETSADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEW 172 QE E + G Q E++ + ++ R E+ + E+E++ +K + + E Sbjct: 197 QEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQ 256 Query: 173 LGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFK-KKHEEVSQFKE 231 + ++ + ++E+++ ++ + ++ E+++R E + ++ EE + +E Sbjct: 257 MRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQE 316 Query: 232 EGDASEDSPLSSASSQAVTPDEQ 254 E ++ + Q EQ Sbjct: 317 EQMREQEEQMGKQEEQMWEQKEQ 339 >gi|217330641 IWS1 homolog [Homo sapiens] Length = 819 Score = 44.3 bits (103), Expect = 1e-04 Identities = 60/286 (20%), Positives = 114/286 (39%), Gaps = 34/286 (11%) Query: 7 DRIQPHIM---TDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLE 63 D ++P I ++ P ++ ++PP+ + SEEL P P S E Sbjct: 176 DALKPQISDSESEEPPRHQASDSENEEPPK--PRMSDSESEEL-----PKPQVSDSESEE 228 Query: 64 GALTKGSQEERRKLQGNMLLNSSMEDKMLKE-NPEEKLFIVHKAITDLSLQETSADEMTF 122 + S E +L + +S ED + + E + I+D ++ ++ + Sbjct: 229 PPRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASD 288 Query: 123 REGHQWEKIPLSGSNQEIRRQ---KERITE------QPLKEEEDEDRKNKGHQAAEIEWL 173 E + K +S S E ++ + TE Q + ++D DR+NKG E++ Sbjct: 289 SENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDT-EMQND 347 Query: 174 GFRKPSQADM--LHSKHDEEQKVWDEEIDDDDDDNCNNDED----EVRVIEFKKKHEEVS 227 F S D HS EE++ +++D D+D+ +E + V+ + E+ S Sbjct: 348 SFHSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKAS 407 Query: 228 QFK-------EEGDASEDSPLSSASSQAVTPDEQPTLGKKSDISRN 266 K ++ D+ S S + + D + GK+ +N Sbjct: 408 AKKSRVVSDADDSDSDAVSDKSGKREKTIASDSEEEAGKELSDKKN 453 >gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo sapiens] Length = 1251 Score = 43.9 bits (102), Expect = 2e-04 Identities = 39/178 (21%), Positives = 79/178 (44%), Gaps = 5/178 (2%) Query: 80 NMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQE 139 ++L +E ++ E E H+ ++ S Q T E EK+P S E Sbjct: 293 SILPGGQVEPDLVLEEVEPPWEDAHQDVST-SPQGTEVVPAYEEENKAVEKMPRELSRIE 351 Query: 140 IRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDE-- 197 ++ E E+ +EEE+E+ + + +G + S+ D + +QK+W+E Sbjct: 352 EEKEDEEEEEEEEEEEEEEEVTEVLLDSCVVSQVGVGQ-SEEDGTRPQSTSDQKLWEEVG 410 Query: 198 -EIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQ 254 E + ++ + +EV E +K+ ++ ++ KEE +A ++ S + P+ Q Sbjct: 411 EEAKKEAEEKAKEEAEEVAEEEAEKEPQDWAETKEEPEAEAEAASSGVPATKQHPEVQ 468 >gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sapiens] Length = 805 Score = 43.9 bits (102), Expect = 2e-04 Identities = 57/294 (19%), Positives = 118/294 (40%), Gaps = 38/294 (12%) Query: 16 DVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERR 75 D P +++ + D+ E+ + S ++T SP+P E + +T+ +E + Sbjct: 278 DGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSPVPQ---EEHSDPEMTEEEKEYQM 334 Query: 76 KLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSG 135 L MLL ++L + +E+++ V K D + T A + + G Sbjct: 335 MLLTKMLLT-----EILLDVTDEEIYYVAK---DAHRKATKAPAKQLAQSSALASLTGLG 386 Query: 136 ------SNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHD 189 S + +R +E + +DE+ +++ Q E W RK + +LH K Sbjct: 387 GLGGYGSGDSEDERSDRGSES--SDTDDEELRHRIRQKQEAFW---RKEKEQQLLHDKQM 441 Query: 190 EEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPL-------- 241 EE+K E + + ++ + +++ + ++E ++ +V K+ S L Sbjct: 442 EEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKE 501 Query: 242 --------SSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQR 287 S +SS + T S +S ++YS + S R + K++ Sbjct: 502 KEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRK 555 >gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sapiens] Length = 805 Score = 43.9 bits (102), Expect = 2e-04 Identities = 57/294 (19%), Positives = 118/294 (40%), Gaps = 38/294 (12%) Query: 16 DVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERR 75 D P +++ + D+ E+ + S ++T SP+P E + +T+ +E + Sbjct: 278 DGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSPVPQ---EEHSDPEMTEEEKEYQM 334 Query: 76 KLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSG 135 L MLL ++L + +E+++ V K D + T A + + G Sbjct: 335 MLLTKMLLT-----EILLDVTDEEIYYVAK---DAHRKATKAPAKQLAQSSALASLTGLG 386 Query: 136 ------SNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHD 189 S + +R +E + +DE+ +++ Q E W RK + +LH K Sbjct: 387 GLGGYGSGDSEDERSDRGSES--SDTDDEELRHRIRQKQEAFW---RKEKEQQLLHDKQM 441 Query: 190 EEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPL-------- 241 EE+K E + + ++ + +++ + ++E ++ +V K+ S L Sbjct: 442 EEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKE 501 Query: 242 --------SSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQR 287 S +SS + T S +S ++YS + S R + K++ Sbjct: 502 KEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRK 555 >gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] Length = 755 Score = 43.5 bits (101), Expect = 2e-04 Identities = 37/193 (19%), Positives = 85/193 (44%), Gaps = 34/193 (17%) Query: 85 SSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEI---- 140 + +E + +E E++L H+ + D L+E ++ F + + + GS +E Sbjct: 568 NGLEKDLDEEGSEKEL---HENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDS 624 Query: 141 -RRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEI 199 +++E T + + ++E ++++++ E+ + AD + D ++K+++E Sbjct: 625 DEKEEEEDTYEKVFDDESDEKEDE-------EYADEKGLEAADKKAEEGDADEKLFEESD 677 Query: 200 DDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDAS-------------------EDSP 240 D +D+D + ++ F+ F EE D+S E+ P Sbjct: 678 DKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLGGFGSVEEGP 737 Query: 241 LSSASSQAVTPDE 253 LS+ SS ++ D+ Sbjct: 738 LSTGSSFILSSDD 750 Score = 42.7 bits (99), Expect = 4e-04 Identities = 48/206 (23%), Positives = 96/206 (46%), Gaps = 17/206 (8%) Query: 61 SLEGALTKGSQEERRKLQGNM--LLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSAD 118 S EG +GS+E+ K + L N E+ + KE+ ++ + ++ ++ + S + Sbjct: 485 SEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDD---LNKESEEEVGPTKESEE 541 Query: 119 EMTFREGHQ--WEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFR 176 + + +E + EK GS +E +E E+ L EE E ++ E+E Sbjct: 542 DDSEKESDEDCSEKQSEDGSEREF---EENGLEKDLDEEGSEKELHENVLDKELE----- 593 Query: 177 KPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDAS 236 + ++ + D +KV DEE + + D ++DE E ++K ++ S KE+ + + Sbjct: 594 -ENDSENSEFEDDGSEKVLDEEGSEREFDE-DSDEKEEEEDTYEKVFDDESDEKEDEEYA 651 Query: 237 EDSPLSSASSQAVTPDEQPTLGKKSD 262 ++ L +A +A D L ++SD Sbjct: 652 DEKGLEAADKKAEEGDADEKLFEESD 677 >gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] Length = 755 Score = 43.5 bits (101), Expect = 2e-04 Identities = 37/193 (19%), Positives = 85/193 (44%), Gaps = 34/193 (17%) Query: 85 SSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEI---- 140 + +E + +E E++L H+ + D L+E ++ F + + + GS +E Sbjct: 568 NGLEKDLDEEGSEKEL---HENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDS 624 Query: 141 -RRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEI 199 +++E T + + ++E ++++++ E+ + AD + D ++K+++E Sbjct: 625 DEKEEEEDTYEKVFDDESDEKEDE-------EYADEKGLEAADKKAEEGDADEKLFEESD 677 Query: 200 DDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDAS-------------------EDSP 240 D +D+D + ++ F+ F EE D+S E+ P Sbjct: 678 DKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLGGFGSVEEGP 737 Query: 241 LSSASSQAVTPDE 253 LS+ SS ++ D+ Sbjct: 738 LSTGSSFILSSDD 750 Score = 42.7 bits (99), Expect = 4e-04 Identities = 48/206 (23%), Positives = 96/206 (46%), Gaps = 17/206 (8%) Query: 61 SLEGALTKGSQEERRKLQGNM--LLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSAD 118 S EG +GS+E+ K + L N E+ + KE+ ++ + ++ ++ + S + Sbjct: 485 SEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDD---LNKESEEEVGPTKESEE 541 Query: 119 EMTFREGHQ--WEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFR 176 + + +E + EK GS +E +E E+ L EE E ++ E+E Sbjct: 542 DDSEKESDEDCSEKQSEDGSEREF---EENGLEKDLDEEGSEKELHENVLDKELE----- 593 Query: 177 KPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDAS 236 + ++ + D +KV DEE + + D ++DE E ++K ++ S KE+ + + Sbjct: 594 -ENDSENSEFEDDGSEKVLDEEGSEREFDE-DSDEKEEEEDTYEKVFDDESDEKEDEEYA 651 Query: 237 EDSPLSSASSQAVTPDEQPTLGKKSD 262 ++ L +A +A D L ++SD Sbjct: 652 DEKGLEAADKKAEEGDADEKLFEESD 677 >gi|4506467 radixin [Homo sapiens] Length = 583 Score = 43.5 bits (101), Expect = 2e-04 Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 12/110 (10%) Query: 185 HSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSA 244 H +HDE E+ ++ N ++E+ RV E +K Q + + S L+ A Sbjct: 486 HDEHDENNAEASAELSNEGVMNHRSEEE--RVTETQKNERVKKQLQ-----ALSSELAQA 538 Query: 245 SSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESM 294 + + R+ Y + R+IR+GNTKQRIDEFE+M Sbjct: 539 RDETKKTQNDVLHAENVKAGRDKYK-----TLRQIRQGNTKQRIDEFEAM 583 >gi|4504487 histidine rich calcium binding protein precursor [Homo sapiens] Length = 699 Score = 43.5 bits (101), Expect = 2e-04 Identities = 35/130 (26%), Positives = 52/130 (40%), Gaps = 4/130 (3%) Query: 111 SLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEI 170 S Q+ DE+ E H I G E E+ +EEE+E GHQA Sbjct: 159 SHQDEDEDEVVSSEHHH--HILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRH 216 Query: 171 EWLGFRKPSQADMLHSKH--DEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQ 228 G + H H + +E+ DDDDDD+ ++D+D+V + + H Sbjct: 217 RGHGSEEDEDVSDGHHHHGPSHRHQGHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGH 276 Query: 229 FKEEGDASED 238 EE + D Sbjct: 277 GIEEDEDVSD 286 Score = 32.3 bits (72), Expect = 0.52 Identities = 24/104 (23%), Positives = 44/104 (42%), Gaps = 19/104 (18%) Query: 137 NQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWD 196 + E Q E+ T +++EDE+ + +GH S + EE++ D Sbjct: 498 DDESSEQGEKGTHHGSRDQEDEEDEEEGHGL------------------SLNQEEEEEED 539 Query: 197 EEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSP 240 +E +++++D +E H E + +EEG ED P Sbjct: 540 KEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEEEG-LEEDEP 582 Score = 29.6 bits (65), Expect = 3.3 Identities = 28/146 (19%), Positives = 59/146 (40%), Gaps = 13/146 (8%) Query: 117 ADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQ-----PLKEEEDEDRKNKGHQAAEIE 171 +DE F++ ++ E +P ++ R + E ++ + P + +D + Q I+ Sbjct: 401 SDEEDFQDEYKTE-VPHHHHHRVPREEDEEVSAELGHQAPSHRQSHQDEETGHGQRGSIK 459 Query: 172 WLGFRKPSQA---DMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQ 228 + P D H + D+ + EE + ++D + ++DE K H Sbjct: 460 EMSHHPPGHTVVKDRSHLRKDDSE----EEKEKEEDPGSHEEDDESSEQGEKGTHHGSRD 515 Query: 229 FKEEGDASEDSPLSSASSQAVTPDEQ 254 ++E D E LS + D++ Sbjct: 516 QEDEEDEEEGHGLSLNQEEEEEEDKE 541 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 43.1 bits (100), Expect = 3e-04 Identities = 45/172 (26%), Positives = 82/172 (47%), Gaps = 17/172 (9%) Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITD----LSLQETSADEMTFREGH 126 QEE+ Q + E+KM ++ EEK+ + I + + QE E + G Sbjct: 500 QEEKMHDQEEKI--REQEEKMWRQ--EEKIREQEEKIREQEEKIREQEEMMQEQEEKMGE 555 Query: 127 QWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHS 186 Q EK+ +++RRQ+E+I EQ EE+ ++K K + E W K + + + Sbjct: 556 QEEKMQ---EQEKMRRQEEKIREQ---EEKIREQKEKIREQEEKIWEQEEKIREQEEM-- 607 Query: 187 KHDEEQKVWD-EEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASE 237 ++E+K+W+ EE + ++ E+++R E K +EV ++E E Sbjct: 608 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 659 Score = 38.1 bits (87), Expect = 0.009 Identities = 43/208 (20%), Positives = 94/208 (45%), Gaps = 20/208 (9%) Query: 36 QQTITKISEELTDVDSPL-PHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKE 94 Q + ++ E D+ S L ++ LE AL+ + ++++ +++ KE Sbjct: 150 QHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKA--------DRYIEELTKE 201 Query: 95 NPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKER----ITEQ 150 L + ITD L+E +A + + EK + + +E++R+ ER + +Q Sbjct: 202 RDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQ 261 Query: 151 PLKEEEDEDRKNKGHQAAEIEW------LGFRKPSQADMLHSKHDEEQKVWDEEIDDDDD 204 L+ E D K +A+++ L R Q + + +E+ + W+E+I + + Sbjct: 262 QLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQ-EQE 320 Query: 205 DNCNNDEDEVRVIEFKKKHEEVSQFKEE 232 + E+++R E K + +E +++E Sbjct: 321 EKIREQEEKIREQEEKMRRQEEMMWEKE 348 Score = 35.0 bits (79), Expect = 0.079 Identities = 31/161 (19%), Positives = 69/161 (42%), Gaps = 17/161 (10%) Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130 QEE+ + Q M+ E+KM ++ EE ++ ++M E WEK Sbjct: 333 QEEKMRRQEEMMWEK--EEKMRRQ--EEMMW-------------EKEEKMRRLEEMMWEK 375 Query: 131 IPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDE 190 +E ++E+I EQ K +E+E + + + + + ++ + ++ Sbjct: 376 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 435 Query: 191 EQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKE 231 E+K+W +E + + +E E ++ E++ + +E Sbjct: 436 EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE 476 Score = 34.7 bits (78), Expect = 0.10 Identities = 32/153 (20%), Positives = 71/153 (46%), Gaps = 15/153 (9%) Query: 88 EDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKERI 147 ++K+ K+ EEK++ + + D QE E + Q EKI ++IR Q+E+I Sbjct: 487 QEKIRKQ--EEKVWRQEEKMHD---QEEKIREQEEKMWRQEEKI--REQEEKIREQEEKI 539 Query: 148 TEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSK--------HDEEQKVWDEEI 199 EQ +E E++ + + + + R+ + K ++E+K+W++E Sbjct: 540 REQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEE 599 Query: 200 DDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEE 232 + + +++E + +K E+ + +E+ Sbjct: 600 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 632 Score = 32.0 bits (71), Expect = 0.67 Identities = 39/170 (22%), Positives = 78/170 (45%), Gaps = 18/170 (10%) Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPE-----EKLFIVHKAITDLSLQETSADEMTFREG 125 +EE+R+ Q M +++ ++E E EK+ K + QE + Sbjct: 454 EEEKRQEQEEMW----RQEEKIREQEEIWRQKEKMHEQEK----IRKQEEKVWRQEEKMH 505 Query: 126 HQWEKIPLSGSNQEIRRQKERITEQP--LKEEEDEDRKNKGHQAAEIEWLGFRKPSQADM 183 Q EKI +++ RQ+E+I EQ ++E+E++ R+ + + E +G ++ + Sbjct: 506 DQEEKI--REQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ 563 Query: 184 LHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFK-KKHEEVSQFKEE 232 + EE+ EE + + E+++ E K ++ EE+ Q +EE Sbjct: 564 EKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEE 613 Score = 28.9 bits (63), Expect = 5.7 Identities = 29/118 (24%), Positives = 57/118 (48%), Gaps = 19/118 (16%) Query: 69 GSQEERRKLQGNMLLNSS----MEDKMLKENP-----EEKLFIVHKAITDLSLQETSADE 119 G QEE+ + Q M E+K+ ++ EEK++ + I + QE E Sbjct: 554 GEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIRE---QEEMMQE 610 Query: 120 MTFREGHQWEKI-----PLSGSNQEIRRQKERITEQP--LKEEEDEDRKNKGHQAAEI 170 + Q EK+ + +++RRQ+E++ EQ L+++E++ ++++ H A I Sbjct: 611 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668 >gi|115529449 upstream binding transcription factor, RNA polymerase I isoform b [Homo sapiens] Length = 727 Score = 43.1 bits (100), Expect = 3e-04 Identities = 57/221 (25%), Positives = 92/221 (41%), Gaps = 38/221 (17%) Query: 30 KPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMED 89 KPP NG Q K S+EL + L H P E + GS+ +R + S E Sbjct: 532 KPPMNGYQ---KFSQELLS-NGELNHL---PLKERMVEIGSRWQR-------ISQSQKEH 577 Query: 90 KMLKENPEEKLFIVHKAITDLSLQETSADEMTFRE---GHQWEKIPLSGSNQEIRRQK-E 145 ++K + VH + SL + D ++E + L G N + R + Sbjct: 578 YKKLAEEQQKQYKVHLDLWVKSL--SPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQ 635 Query: 146 RITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDD 205 +E +EEDED +++ + + E G D S ++E + DE +DD+D+ Sbjct: 636 SKSESEEDDEEDEDDEDEDEEEEDDE-NGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 694 Query: 206 NCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASS 246 + + D+DE +E + SE S SS+SS Sbjct: 695 DDDEDDDE-----------------DEDNESEGSSSSSSSS 718 >gi|115529451 upstream binding transcription factor, RNA polymerase I isoform b [Homo sapiens] Length = 727 Score = 43.1 bits (100), Expect = 3e-04 Identities = 57/221 (25%), Positives = 92/221 (41%), Gaps = 38/221 (17%) Query: 30 KPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMED 89 KPP NG Q K S+EL + L H P E + GS+ +R + S E Sbjct: 532 KPPMNGYQ---KFSQELLS-NGELNHL---PLKERMVEIGSRWQR-------ISQSQKEH 577 Query: 90 KMLKENPEEKLFIVHKAITDLSLQETSADEMTFRE---GHQWEKIPLSGSNQEIRRQK-E 145 ++K + VH + SL + D ++E + L G N + R + Sbjct: 578 YKKLAEEQQKQYKVHLDLWVKSL--SPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQ 635 Query: 146 RITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDD 205 +E +EEDED +++ + + E G D S ++E + DE +DD+D+ Sbjct: 636 SKSESEEDDEEDEDDEDEDEEEEDDE-NGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 694 Query: 206 NCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASS 246 + + D+DE +E + SE S SS+SS Sbjct: 695 DDDEDDDE-----------------DEDNESEGSSSSSSSS 718 >gi|7657671 upstream binding transcription factor, RNA polymerase I isoform a [Homo sapiens] Length = 764 Score = 43.1 bits (100), Expect = 3e-04 Identities = 57/221 (25%), Positives = 92/221 (41%), Gaps = 38/221 (17%) Query: 30 KPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMED 89 KPP NG Q K S+EL + L H P E + GS+ +R + S E Sbjct: 569 KPPMNGYQ---KFSQELLS-NGELNHL---PLKERMVEIGSRWQR-------ISQSQKEH 614 Query: 90 KMLKENPEEKLFIVHKAITDLSLQETSADEMTFRE---GHQWEKIPLSGSNQEIRRQK-E 145 ++K + VH + SL + D ++E + L G N + R + Sbjct: 615 YKKLAEEQQKQYKVHLDLWVKSL--SPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQ 672 Query: 146 RITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDD 205 +E +EEDED +++ + + E G D S ++E + DE +DD+D+ Sbjct: 673 SKSESEEDDEEDEDDEDEDEEEEDDE-NGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 731 Query: 206 NCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASS 246 + + D+DE +E + SE S SS+SS Sbjct: 732 DDDEDDDE-----------------DEDNESEGSSSSSSSS 755 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 42.4 bits (98), Expect = 5e-04 Identities = 44/209 (21%), Positives = 80/209 (38%), Gaps = 32/209 (15%) Query: 73 ERRKLQGNMLLNSSMEDKMLKEN---PEEKLFIVHKAITDLSLQETSADEMTFREGHQWE 129 E +K+Q E+KM +E EK K + ++M +E + WE Sbjct: 428 EEKKMQEQEKKTRDQEEKMQEEERIREREK-----KMREEEETMREQEEKMQKQEENMWE 482 Query: 130 KIPLSGSNQEIRRQKERITEQPLKEEEDE---DRKNKGHQAAEI------EWLGFRKPSQ 180 + Q + QKE++ EQ +E++E +++ K E+ W + Q Sbjct: 483 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 542 Query: 181 ADML----HSKHDEEQKVWDEEIDDD-----------DDDNCNNDEDEVRVIEFKKKHEE 225 D + D+EQK+WD+E + D + +E+ +R E K + EE Sbjct: 543 EDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE 602 Query: 226 VSQFKEEGDASEDSPLSSASSQAVTPDEQ 254 ++E E + + E+ Sbjct: 603 EMMREQEEKMQEQEEKMQEQEEKMWEQEE 631 Score = 40.0 bits (92), Expect = 0.002 Identities = 42/186 (22%), Positives = 82/186 (44%), Gaps = 27/186 (14%) Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130 QEE+ Q L E KM ++ EEK++ K + + +E E RE Sbjct: 291 QEEKMWRQEERL--REQEGKMREQ--EEKMWRQEKRLREQE-KELREQEKELRE------ 339 Query: 131 IPLSGSNQEIRRQKERITEQPLK--EEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKH 188 +E+R Q+E++ EQ K E+E++ R+ + + E L ++ + Sbjct: 340 ------QKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 393 Query: 189 DEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQA 248 D+E+++W++ D+ E+ +R E +K E+V + +EE E + + Sbjct: 394 DQEERMWEQ------DERLREKEERMR--EQEKMWEQVEKMREEKKMQEQEKKTRDQEEK 445 Query: 249 VTPDEQ 254 + +E+ Sbjct: 446 MQEEER 451 Score = 38.9 bits (89), Expect = 0.006 Identities = 34/162 (20%), Positives = 66/162 (40%), Gaps = 12/162 (7%) Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130 +E +K++ + E+KM +E E+ K + ++M +E WE+ Sbjct: 592 REREKKMREEEEMMREQEEKM-QEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 650 Query: 131 IPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDE 190 Q + QKE++ E +E++ K + E W Q M ++ Sbjct: 651 EEKMWEQQRLPEQKEKLWEHEKMQEQE-----KMQEQEEKIW------EQEKMEKKTQEQ 699 Query: 191 EQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEE 232 E+K WD+E +++ ++ E ++ EE Q +EE Sbjct: 700 EKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEE 741 Score = 34.7 bits (78), Expect = 0.10 Identities = 36/190 (18%), Positives = 77/190 (40%), Gaps = 23/190 (12%) Query: 66 LTKGSQEERRKL--QGNMLLNSSMEDKMLKENPEEKLFIVH--KAITDLSLQETSADEMT 121 + K +QE+ +K Q M SM ++ K EE++ K + +EM Sbjct: 692 MEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMW 751 Query: 122 FREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEED---EDRKNKGHQAAEIEWLGFRKP 178 +E WE+ Q + QKE++ E +E++ E + Q ++ + Sbjct: 752 EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMR 811 Query: 179 SQADMLHSKHD----EEQKVWDEE------------IDDDDDDNCNNDEDEVRVIEFKKK 222 Q + + + + +E+K+W +E ++ ++ E+++R E K + Sbjct: 812 GQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMR 871 Query: 223 HEEVSQFKEE 232 +E ++E Sbjct: 872 GQEEKMREQE 881 Score = 33.9 bits (76), Expect = 0.18 Identities = 36/189 (19%), Positives = 78/189 (41%), Gaps = 31/189 (16%) Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130 QEE+ Q L ++K ++E E+K+ + + + + +E + WE+ Sbjct: 367 QEEKMWRQEERLWE---QEKQMREQ-EQKMRDQEERMWEQDERLREKEERMREQEKMWEQ 422 Query: 131 IPLSGSNQEIRRQKERITEQPLKEEEDE---DRKNKGHQAAEI----------------- 170 + ++++ Q+++ +Q K +E+E +R+ K + E Sbjct: 423 VEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE 482 Query: 171 ----EWLGFRKPSQADML---HSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKH 223 EW R P Q + L ++E+K+W++E D + E ++ E ++ Sbjct: 483 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 542 Query: 224 EEVSQFKEE 232 E+ +EE Sbjct: 543 EDQMWEQEE 551 Score = 32.7 bits (73), Expect = 0.39 Identities = 28/130 (21%), Positives = 58/130 (44%), Gaps = 11/130 (8%) Query: 71 QEERRKLQGNMLLNSSMEDKMLKEN--PEEKLFIVHKAITDLSLQETSADEMTFREGHQW 128 QE+ K+ E+KM ++ PE+K K +QE ++M +E W Sbjct: 634 QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQK----EKLWEHEKMQEQ--EKMQEQEEKIW 687 Query: 129 EKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKH 188 E+ + QE Q+++ +Q EE+ R+ + E E + ++ + Sbjct: 688 EQEKMEKKTQE---QEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQ 744 Query: 189 DEEQKVWDEE 198 ++E+++W++E Sbjct: 745 EQEEEMWEQE 754 Score = 30.4 bits (67), Expect = 2.0 Identities = 27/134 (20%), Positives = 64/134 (47%), Gaps = 11/134 (8%) Query: 71 QEERRKLQGNMLLNSSMEDKMLKENP----EEKLFIVHKAITDLSLQETSADEMTFREGH 126 QEE+ + Q M E KM ++ E++++ + + D + +E ++ Sbjct: 516 QEEKIRDQEEMW---GQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQ 572 Query: 127 QWEKIPLSGSNQEIRRQKERITEQP--LKEEEDEDRKNKGHQAAEIEWLGFRKPSQADML 184 + EK + +E R++ER+ E+ ++EEE+ R+ + + E + ++ + Sbjct: 573 EQEK--KTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQE 630 Query: 185 HSKHDEEQKVWDEE 198 ++E+K+W++E Sbjct: 631 EKMQEQEEKMWEQE 644 Score = 29.6 bits (65), Expect = 3.3 Identities = 30/168 (17%), Positives = 77/168 (45%), Gaps = 4/168 (2%) Query: 88 EDKMLKENPEEKLFIVHKAITDLSLQ-ETSADEMTFREGHQWEKIPLSGSNQEIRRQKER 146 ED+M ++ EEK+ + + D + E E + Q EK+ +E R +K R Sbjct: 543 EDQMWEQ--EEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRE-REKKMR 599 Query: 147 ITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDN 206 E+ ++E+E++ ++ + + E + ++ + ++E+K+W++E + Sbjct: 600 EEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 659 Query: 207 CNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQ 254 ++++ E ++ E++ + +E+ E + + T D++ Sbjct: 660 LPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQE 707 >gi|161702986 ezrin [Homo sapiens] Length = 586 Score = 42.0 bits (97), Expect = 7e-04 Identities = 63/241 (26%), Positives = 103/241 (42%), Gaps = 48/241 (19%) Query: 68 KGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQ 127 K +QEE +L+ D+M +E+L +A+ + QE A E+ Sbjct: 380 KRAQEEAERLEA---------DRMAALRAKEEL--ERQAVDQIKSQEQLAAELA----EY 424 Query: 128 WEKIPLSGSNQEIRRQKERITEQ---PLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADML 184 KI L +E RR+KE E+ KE +D+ K K E+ + P + Sbjct: 425 TAKIALL---EEARRRKEDEVEEWQHRAKEAQDDLVKTK----EELHLVMTAPPPPPPPV 477 Query: 185 HS--KHDEEQKVWDEEIDDD------DDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDAS 236 + + ++ + DE + + +D +E + I +K+E V + Sbjct: 478 YEPVSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQR-------- 529 Query: 237 EDSPLSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISY---RKIRKGNTKQRIDEFES 293 + LSS SQA +++ +DI N R Y R+IR+GNTKQRIDEFE+ Sbjct: 530 QLLTLSSELSQARDENKRT----HNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEA 585 Query: 294 M 294 + Sbjct: 586 L 586 >gi|21614499 ezrin [Homo sapiens] Length = 586 Score = 42.0 bits (97), Expect = 7e-04 Identities = 63/241 (26%), Positives = 103/241 (42%), Gaps = 48/241 (19%) Query: 68 KGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQ 127 K +QEE +L+ D+M +E+L +A+ + QE A E+ Sbjct: 380 KRAQEEAERLEA---------DRMAALRAKEEL--ERQAVDQIKSQEQLAAELA----EY 424 Query: 128 WEKIPLSGSNQEIRRQKERITEQ---PLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADML 184 KI L +E RR+KE E+ KE +D+ K K E+ + P + Sbjct: 425 TAKIALL---EEARRRKEDEVEEWQHRAKEAQDDLVKTK----EELHLVMTAPPPPPPPV 477 Query: 185 HS--KHDEEQKVWDEEIDDD------DDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDAS 236 + + ++ + DE + + +D +E + I +K+E V + Sbjct: 478 YEPVSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQR-------- 529 Query: 237 EDSPLSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISY---RKIRKGNTKQRIDEFES 293 + LSS SQA +++ +DI N R Y R+IR+GNTKQRIDEFE+ Sbjct: 530 QLLTLSSELSQARDENKRT----HNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEA 585 Query: 294 M 294 + Sbjct: 586 L 586 >gi|84043963 eukaryotic translation initiation factor 5B [Homo sapiens] Length = 1220 Score = 42.0 bits (97), Expect = 7e-04 Identities = 40/202 (19%), Positives = 83/202 (41%), Gaps = 31/202 (15%) Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130 ++ER K +G +L S E + E L ++ ++ +++ + E + +K Sbjct: 397 RKERLKKEGKLLTKSQRE---ARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKK 453 Query: 131 IPLSGSNQEIRRQKE-----RITEQ----------PLKEEEDEDRKNKGHQAAEIEWLGF 175 IP ++E+ E + EQ P++ EE+ED ++ G +W Sbjct: 454 IPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLD----DWEAM 509 Query: 176 RKPSQADMLHSKH---------DEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEV 226 + + + +EE++ +EE +D++ + +E E E ++ E+V Sbjct: 510 ASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKV 569 Query: 227 SQFKEEGDASEDSPLSSASSQA 248 S K+ G + P SS + Sbjct: 570 SDEKDSGKTLDKKPSKEMSSDS 591 Score = 29.3 bits (64), Expect = 4.4 Identities = 27/138 (19%), Positives = 65/138 (47%), Gaps = 12/138 (8%) Query: 137 NQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWL--GFRKPSQADMLHSKHDEEQ-- 192 N+ +++K++ ++ KEE+++++K KG A ++ + K + + + +EE+ Sbjct: 309 NEGDKKKKDKKKKKGEKEEKEKEKK-KGPSKATVKAMQEALAKLKEEEERQKREEEERIK 367 Query: 193 -------KVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSAS 245 K +EE + + +++ R KK+ + +++ + E A ++ L Sbjct: 368 RLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQ 427 Query: 246 SQAVTPDEQPTLGKKSDI 263 +Q V + +L KK I Sbjct: 428 AQGVEVPSKDSLPKKRPI 445 >gi|55956788 nucleolin [Homo sapiens] Length = 710 Score = 41.2 bits (95), Expect = 0.001 Identities = 36/160 (22%), Positives = 66/160 (41%), Gaps = 11/160 (6%) Query: 90 KMLKENPEEKLFIVHKAITDLSLQ-ETSADEMTFREGHQWEKIPLSGSNQEIRRQKERIT 148 K P +K KA+T + T + G + IP G+ +KE Sbjct: 87 KKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAAIPAKGAKNGKNAKKEDSD 146 Query: 149 EQPL--KEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDN 206 E+ EE++ED +++ EIE + + A + DE+ + +++ DD++DD+ Sbjct: 147 EEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDS 206 Query: 207 CN--------NDEDEVRVIEFKKKHEEVSQFKEEGDASED 238 + +V+ K K+ + +EE D ED Sbjct: 207 EEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDED 246 Score = 41.2 bits (95), Expect = 0.001 Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 10/83 (12%) Query: 149 EQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCN 208 E +EE E KG +AA++ P +A + DEE+ DE+ DDD+DD + Sbjct: 203 EDDSEEEAMETTPAKGKKAAKVV------PVKAKNVAEDEDEEEDDEDEDDDDDEDDEDD 256 Query: 209 NDEDEVRVIEFKKKHEEVSQFKE 231 +DED+ E +++ EE KE Sbjct: 257 DDEDD----EEEEEEEEEEPVKE 275 Score = 33.5 bits (75), Expect = 0.23 Identities = 18/88 (20%), Positives = 48/88 (54%), Gaps = 6/88 (6%) Query: 153 KEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDED 212 ++++D++ + +A E +K ++ + +K+ E + +E+ +D+DDD+ +DED Sbjct: 196 EDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDED 255 Query: 213 EVRVIEFKKKHEEVSQFKEEGDASEDSP 240 + + +E + +EE + +++P Sbjct: 256 D------DDEDDEEEEEEEEEEPVKEAP 277 >gi|55741677 SET domain containing 1A [Homo sapiens] Length = 1707 Score = 40.8 bits (94), Expect = 0.001 Identities = 34/143 (23%), Positives = 57/143 (39%), Gaps = 30/143 (20%) Query: 155 EEDEDRKNKGHQAAEIEWLGFRKPSQAD-------------MLHSKHDEEQKVWDEEIDD 201 EEDED + +A E G + P + + L S+ +E + E D+ Sbjct: 919 EEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDE 978 Query: 202 DDDDNCNNDEDEVRVIEFKKKHEEVSQFKE-----------------EGDASEDSPLSSA 244 +DD+ DED ++ KK EVS ++ E D++ DS SS+ Sbjct: 979 EDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSS 1038 Query: 245 SSQAVTPDEQPTLGKKSDISRNA 267 SS + + + S S ++ Sbjct: 1039 SSSSSSSSSSSSSSSSSSSSESS 1061 >gi|210032580 SET domain containing 1B [Homo sapiens] Length = 1923 Score = 40.8 bits (94), Expect = 0.001 Identities = 33/109 (30%), Positives = 52/109 (47%), Gaps = 20/109 (18%) Query: 140 IRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEI 199 +RR+ R E EEDE K S ++ S +EE+ +EE Sbjct: 1019 VRRRPARPLELDSGGEEDE------------------KESLSEEQESTEEEEEAEEEEEE 1060 Query: 200 DDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQA 248 +DDDDD+ ++D DE + E S+ K+EGD+ E+ +S +S+A Sbjct: 1061 EDDDDDD-SDDRDESENDDEDTALSEASE-KDEGDSDEEETVSIVTSKA 1107 Score = 32.0 bits (71), Expect = 0.67 Identities = 35/176 (19%), Positives = 69/176 (39%), Gaps = 45/176 (25%) Query: 125 GHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADML 184 G + EK LS + ++E E+ ++++D+D ++ + E + S+ D Sbjct: 1033 GEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKD-- 1090 Query: 185 HSKHDEEQKVW------------------DEEIDDDDDDNCNNDEDEVRVIEFKKKHEEV 226 DEE+ V + E + + + DE+EV E +++ EE Sbjct: 1091 EGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEE 1150 Query: 227 SQFKEEGDAS----------EDSPLSSAS---------------SQAVTPDEQPTL 257 EE AS E++ L+ + ++AV P+E+P++ Sbjct: 1151 EMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSM 1206 >gi|9257192 adducin 2 isoform a [Homo sapiens] Length = 726 Score = 40.4 bits (93), Expect = 0.002 Identities = 40/149 (26%), Positives = 65/149 (43%), Gaps = 19/149 (12%) Query: 114 ETSADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQA---AEI 170 E S+ M R + + +PL QE+ + +I EQ +D K+ G Q+ A + Sbjct: 469 EKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQ-----NRQDVKSAGPQSQLLASV 523 Query: 171 EWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFK 230 R PS L SK DE+ K DD ++ N ++ E ++ +EV + K Sbjct: 524 IAEKSRSPSTESQLMSKGDEDTK-------DDSEETVPNPFSQLTDQELEEYKKEVERKK 576 Query: 231 EEGDASEDS----PLSSASSQAVTPDEQP 255 E D +++ P S A S +P + P Sbjct: 577 LELDGEKETAPEEPGSPAKSAPASPVQSP 605 >gi|60498973 myelin transcription factor 1-like [Homo sapiens] Length = 1184 Score = 40.4 bits (93), Expect = 0.002 Identities = 29/121 (23%), Positives = 59/121 (48%), Gaps = 17/121 (14%) Query: 154 EEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDE 213 E+ DE +++G + +E +P D + D E++ EE D+DDD++ + EDE Sbjct: 97 EDMDEKEEDEGEEYSEDN----DEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDE 152 Query: 214 VRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSDISRNAYSRYNT 273 ++ EE + +EE + +ED ++ +++ + E K D + + Y Y+ Sbjct: 153 -------EEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTE------KDDNNNDEYDNYDE 199 Query: 274 I 274 + Sbjct: 200 L 200 Score = 28.5 bits (62), Expect = 7.4 Identities = 25/116 (21%), Positives = 54/116 (46%), Gaps = 20/116 (17%) Query: 149 EQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCN 208 E+ +EEE+E+ +N+ HQ + H+ E+ D+++D+ N Sbjct: 155 EEEEEEEEEEEEENEDHQM------------------NCHNTRIMQDTEKDDNNNDEYDN 196 Query: 209 NDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSDIS 264 DE + + K E + ++ ++ +S ++++S D+ LG+KS++S Sbjct: 197 YDELVAKSLLNLGKIAEDAAYRARTESEMNS--NTSNSLEDDSDKNENLGRKSELS 250 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.307 0.126 0.352 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,399,154 Number of Sequences: 37866 Number of extensions: 622361 Number of successful extensions: 6020 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 137 Number of HSP's successfully gapped in prelim test: 353 Number of HSP's that attempted gapping in prelim test: 3626 Number of HSP's gapped (non-prelim): 1461 length of query: 297 length of database: 18,247,518 effective HSP length: 102 effective length of query: 195 effective length of database: 14,385,186 effective search space: 2805111270 effective search space used: 2805111270 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.