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Search of human proteins with 58331177
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|58331177 ermin, ERM-like protein isoform a [Homo sapiens]
(297 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|58331177 ermin, ERM-like protein isoform a [Homo sapiens] 602 e-172
gi|58331175 ermin, ERM-like protein isoform b [Homo sapiens] 576 e-164
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 50 2e-06
gi|21396500 HIRA interacting protein 3 [Homo sapiens] 50 2e-06
gi|4505257 moesin [Homo sapiens] 46 3e-05
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 46 5e-05
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 45 6e-05
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 45 1e-04
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 45 1e-04
gi|217330641 IWS1 homolog [Homo sapiens] 44 1e-04
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H... 44 2e-04
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 44 2e-04
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 44 2e-04
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 44 2e-04
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 44 2e-04
gi|4506467 radixin [Homo sapiens] 44 2e-04
gi|4504487 histidine rich calcium binding protein precursor [Hom... 44 2e-04
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 43 3e-04
gi|115529449 upstream binding transcription factor, RNA polymera... 43 3e-04
gi|115529451 upstream binding transcription factor, RNA polymera... 43 3e-04
gi|7657671 upstream binding transcription factor, RNA polymerase... 43 3e-04
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 42 5e-04
gi|161702986 ezrin [Homo sapiens] 42 7e-04
gi|21614499 ezrin [Homo sapiens] 42 7e-04
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 42 7e-04
gi|55956788 nucleolin [Homo sapiens] 41 0.001
gi|55741677 SET domain containing 1A [Homo sapiens] 41 0.001
gi|210032580 SET domain containing 1B [Homo sapiens] 41 0.001
gi|9257192 adducin 2 isoform a [Homo sapiens] 40 0.002
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 40 0.002
>gi|58331177 ermin, ERM-like protein isoform a [Homo sapiens]
Length = 297
Score = 602 bits (1553), Expect = e-172
Identities = 297/297 (100%), Positives = 297/297 (100%)
Query: 1 MKTLSPDRIQPHIMTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEP 60
MKTLSPDRIQPHIMTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEP
Sbjct: 1 MKTLSPDRIQPHIMTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEP 60
Query: 61 SLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEM 120
SLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEM
Sbjct: 61 SLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEM 120
Query: 121 TFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQ 180
TFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQ
Sbjct: 121 TFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQ 180
Query: 181 ADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSP 240
ADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSP
Sbjct: 181 ADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSP 240
Query: 241 LSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL 297
LSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL
Sbjct: 241 LSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL 297
>gi|58331175 ermin, ERM-like protein isoform b [Homo sapiens]
Length = 284
Score = 576 bits (1484), Expect = e-164
Identities = 284/284 (100%), Positives = 284/284 (100%)
Query: 14 MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEE 73
MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEE
Sbjct: 1 MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEE 60
Query: 74 RRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPL 133
RRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPL
Sbjct: 61 RRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPL 120
Query: 134 SGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQK 193
SGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQK
Sbjct: 121 SGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQK 180
Query: 194 VWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDE 253
VWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDE
Sbjct: 181 VWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDE 240
Query: 254 QPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL 297
QPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL
Sbjct: 241 QPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL 284
>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
Length = 238
Score = 50.4 bits (119), Expect = 2e-06
Identities = 43/194 (22%), Positives = 89/194 (45%), Gaps = 16/194 (8%)
Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130
+E +K++ + E+KM +E E+ K + ++M +E WE+
Sbjct: 8 REREKKMREEEEMMREQEEKM-QEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 66
Query: 131 IPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSK--- 187
Q + QKE++ EQ + E E+R + ++E + +K +Q + + +
Sbjct: 67 EEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEK 126
Query: 188 -HDEEQKVWD-EEIDDDDDDNCNNDEDEVRVIEFK-KKHEEVSQFKEE---------GDA 235
++E+ +W+ EE + ++ E+++R E K ++ EE Q +EE G+A
Sbjct: 127 MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEA 186
Query: 236 SEDSPLSSASSQAV 249
E SP + ++Q +
Sbjct: 187 GEGSPQDNPTAQEI 200
Score = 28.1 bits (61), Expect = 9.7
Identities = 14/61 (22%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
Query: 138 QEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDE 197
+E R +ER E+ ++EEE+ R+ + + E + ++ + ++E+K+W++
Sbjct: 2 REEERMRER--EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59
Query: 198 E 198
E
Sbjct: 60 E 60
>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
Length = 556
Score = 50.1 bits (118), Expect = 2e-06
Identities = 63/304 (20%), Positives = 121/304 (39%), Gaps = 37/304 (12%)
Query: 5 SPDRIQPHIMTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEG 64
SPD P V A + A+ ++ P + + + S+E D P E
Sbjct: 108 SPDYFGPPAKNGVAAEVSPAK---EENPRRASKAVEESSDEERQRDLPAQRGEESSEEEE 164
Query: 65 ALTKGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFRE 124
KG ++ ++ +S+ K +E EE ++ + +A ++ +
Sbjct: 165 KGYKGKTRKKPVVKKQAPGKASVSRKQAREESEE---------SEAEPVQRTAKKVEGNK 215
Query: 125 GHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQAD-M 183
G + K S +EI QK+ E+ ++EEE E+ + KG G RK ++ +
Sbjct: 216 GTKSLKESEQESEEEILAQKKEQREEEVEEEEKEEDEEKGDWKPRTRSNGRRKSAREERS 275
Query: 184 LHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIE--FKKKHEEVSQFK----------E 231
K ++ + D + +++ + ++ +D R E ++K E+ +Q K +
Sbjct: 276 CKQKSQAKRLLGDSDSEEEQKEAASSGDDSGRDREPPVQRKSEDRTQLKGGKRLSGSSED 335
Query: 232 EGDASEDSPLSSASSQAVTPDEQPTLGKKSDISRNAY----------SRYNTISYRKIRK 281
E D+ + P + S + T G++SD+ R R N S + RK
Sbjct: 336 EEDSGKGEPTAKGSRKMARLGS--TSGEESDLEREVSDSEAGGGPQGERKNRSSKKSSRK 393
Query: 282 GNTK 285
G T+
Sbjct: 394 GRTR 397
>gi|4505257 moesin [Homo sapiens]
Length = 577
Score = 46.2 bits (108), Expect = 3e-05
Identities = 63/272 (23%), Positives = 113/272 (41%), Gaps = 23/272 (8%)
Query: 27 NGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERR--KLQGNMLLN 84
N K E ++ KI E ++ L ++E + A + ++ RR +L+
Sbjct: 325 NEKKKREMAEKEKEKIEREKEELMERLK--QIEEQTKKAQQELEEQTRRALELEQERKRA 382
Query: 85 SSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSG--SNQEIRR 142
S +K+ KE E + +L + S D+ +E E L+ S E+ R
Sbjct: 383 QSEAEKLAKERQEAEE-------AKEALLQASRDQKKTQEQLALEMAELTARISQLEMAR 435
Query: 143 QKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDD 202
QK+ +++ +++ AE++ P A+ ++ DE+ + E D
Sbjct: 436 QKKESEAVEWQQKAQMVQEDLEKTRAELK-TAMSTPHVAEPAENEQDEQDENGAEASADL 494
Query: 203 DDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSD 262
D D E +K+E V + + + S L++A ++ +
Sbjct: 495 RADAMAKDRSEEERTTEAEKNERVQKHLK----ALTSELANARDESKKTANDMIHAENMR 550
Query: 263 ISRNAYSRYNTISYRKIRKGNTKQRIDEFESM 294
+ R+ Y + R+IR+GNTKQRIDEFESM
Sbjct: 551 LGRDKYK-----TLRQIRQGNTKQRIDEFESM 577
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 45.8 bits (107), Expect = 5e-05
Identities = 44/199 (22%), Positives = 87/199 (43%), Gaps = 16/199 (8%)
Query: 71 QEER-RKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLS-LQETSADEMTFREGHQW 128
Q+ER R+ + M M ++ K EE++ K + + ++M +E + W
Sbjct: 364 QDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMW 423
Query: 129 EKIPLSGSNQEIRRQKERITEQPLKEEEDE---DRKNKGHQAAEI------EWLGFRKPS 179
E+ Q + QKE++ EQ +E++E +++ K E+ W +
Sbjct: 424 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 483
Query: 180 QADML----HSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDA 235
Q D + D+EQK+WD+E + D +++E R+ E KK ++ + +EE
Sbjct: 484 QEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEE-RMREQKKMWQQEEKMREEKKT 542
Query: 236 SEDSPLSSASSQAVTPDEQ 254
E + + + +E+
Sbjct: 543 QEQEKKTWDQEEKMREEER 561
Score = 39.7 bits (91), Expect = 0.003
Identities = 43/215 (20%), Positives = 87/215 (40%), Gaps = 33/215 (15%)
Query: 73 ERRKLQGNMLLNSSMEDKMLKENP-----EEKLFIVHKAITDLSLQETSADE-MTFREGH 126
E++KL+ E+KM ++ EEK++ + + + Q ++ M +E
Sbjct: 301 EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 360
Query: 127 QWEKIPLSGSNQEIRRQKERITEQPLKEEEDE---DRKNKGHQAAEI------------- 170
WE+ +E R++E++ EQ K +E+E +R+ K + E
Sbjct: 361 MWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 420
Query: 171 --------EWLGFRKPSQADML---HSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEF 219
EW R P Q + L ++E+K+W++E D + E ++ E
Sbjct: 421 NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEK 480
Query: 220 KKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQ 254
++ E+ +EE ++ + + DE+
Sbjct: 481 MREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDER 515
Score = 34.3 bits (77), Expect = 0.14
Identities = 26/151 (17%), Positives = 67/151 (44%), Gaps = 4/151 (2%)
Query: 113 QETSADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEW 172
+E E + Q EK+ +E R +K R E+ ++E+E++ ++ + + E
Sbjct: 538 EEKKTQEQEKKTWDQEEKMREEERMRE-REKKMREEEEMMREQEEKMQEQEEKMREQEEK 596
Query: 173 LGFRKPSQADMLHSKHDEEQKVWDEEIDD---DDDDNCNNDEDEVRVIEFKKKHEEVSQF 229
+ ++ + ++E+K+W++E +D + ++ E++++ E K +E
Sbjct: 597 MWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR 656
Query: 230 KEEGDASEDSPLSSASSQAVTPDEQPTLGKK 260
++E E + + E+ G++
Sbjct: 657 EQEEKMREQEEKMQGQEEKMREQEEKMQGQE 687
Score = 33.5 bits (75), Expect = 0.23
Identities = 51/224 (22%), Positives = 95/224 (42%), Gaps = 36/224 (16%)
Query: 36 QQTITKISEELTDVDSPLPH-YRVEPSLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKE 94
+ TIT +EEL ++ L R+ S + + +E +RKL+ L ++ L+E
Sbjct: 177 RNTIT--NEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQE 234
Query: 95 N---PEEKLFIVHKAITD----LSLQETSADEMTFREGHQWEKIP-----LSGSNQEIRR 142
EE+L K I + QE E + Q EK+ L +E+R
Sbjct: 235 EMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELRE 294
Query: 143 QKERITEQP-LKEEEDE---------DRKNKGHQAAEIEW-----LGFRKPSQADMLHSK 187
Q++ + EQ L+E+E++ +++ K + E W L ++ +
Sbjct: 295 QEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKM 354
Query: 188 HDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKE 231
D+E+++W++ D+ E+ +R E + EE Q +E
Sbjct: 355 RDQEERMWEQ------DERLREKEERMREQEKMWEQEEKMQEEE 392
Score = 32.3 bits (72), Expect = 0.52
Identities = 30/161 (18%), Positives = 69/161 (42%), Gaps = 22/161 (13%)
Query: 72 EERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKI 131
E+ K+Q E+KM ++ E+K+ + + + ++M +E WE+
Sbjct: 599 EQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWE------QEEKMQEQEEKMWEQ- 651
Query: 132 PLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEE 191
+++R Q+E++ EQ K + E++ + + + + R+ + +E
Sbjct: 652 -----EEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEE-----KMRGQE 701
Query: 192 QKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEE 232
+K+W +E + +E E ++K E + KE+
Sbjct: 702 EKMWGQE-----EKMWGQEEKMWGQEEMREKEERIRDQKEK 737
Score = 30.8 bits (68), Expect = 1.5
Identities = 29/165 (17%), Positives = 77/165 (46%), Gaps = 13/165 (7%)
Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130
QE+ R+ + M E+KM + E+K++ + + + + +E + W++
Sbjct: 478 QEKMREQEDQMW---EQEEKM--RDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQ 532
Query: 131 IPLSGSNQEIRRQKERITEQPLKEEEDE---DRKNKGHQAAEIEWLGFRKPSQADMLHSK 187
++ + Q+++ +Q K E+E +R+ K + E E + ++ +
Sbjct: 533 EEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMRE--EEEMMREQEEKMQEQEEKM 590
Query: 188 HDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEE 232
++E+K+W++E + + +++E ++++ E+ Q +EE
Sbjct: 591 REQEEKMWEQEEKMQEQEEKMWEQEEKM---WEQEEEDKMQEQEE 632
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 45.4 bits (106), Expect = 6e-05
Identities = 59/296 (19%), Positives = 127/296 (42%), Gaps = 42/296 (14%)
Query: 36 QQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERRKLQGNM-------LLNSSME 88
Q + ++ +L LP +++ + L K Q KLQ + LN E
Sbjct: 229 QLNVKELKRKLERAKLLLPQQQLQAEADH-LGKELQSVSAKLQAQVEENELWNRLNQQQE 287
Query: 89 DKMLKENP-----EEKLFIVHKAITDLSLQETSADEMTF--------REGHQWEKIPLSG 135
+KM ++ EEK+ + I + + +EM + +E WEK
Sbjct: 288 EKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 347
Query: 136 SNQEIRRQKERITEQPLKEEEDE---DRKNKGHQAAEIEWLGFRK--------PSQADML 184
+E ++E+I EQ K +E+E +++ + Q A++ W K Q +M+
Sbjct: 348 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM-WRQEEKIREQEEKIREQEEMM 406
Query: 185 HSKH----DEEQKVWDEEID-DDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDS 239
+ ++E+K+W++E + + ++ E+++R E KK E+ + +E+ + ++
Sbjct: 407 QEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQE-KKIREQEEKIREQEEMMQEQ 465
Query: 240 PLSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMM 295
+ +++ + ++ + R + +KIR+ +++I E E MM
Sbjct: 466 EEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIRE-QEKKIRE--QEEKIREQEEMM 518
Score = 40.4 bits (93), Expect = 0.002
Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 33/179 (18%)
Query: 69 GSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITD----LSLQETSADEMTFRE 124
G QEE+ Q + E+KM ++ EEK+ K I + + QE E +
Sbjct: 414 GEQEEKMWEQEEEM--QEQEEKMRRQ--EEKIREQEKKIREQEEKIREQEEMMQEQEEKM 469
Query: 125 GHQWEKI-----PLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPS 179
G Q K+ + +++RRQ+E+I EQ K E E++ +
Sbjct: 470 GEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIRE---------------- 513
Query: 180 QADMLHSKHDEEQKVWD-EEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASE 237
Q +M+ ++E+K+W+ EE + ++ E+++R E K + +EV ++E E
Sbjct: 514 QEEMMQ---EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 34.3 bits (77), Expect = 0.14
Identities = 36/165 (21%), Positives = 75/165 (45%), Gaps = 6/165 (3%)
Query: 71 QEERRKLQGNMLLNSSMEDKMLKE-NPEEKLFIVHKAITDLSLQETSADEMTFREGHQWE 129
QEE+R+ + + +++ K EEK+ + I + QE E + G Q E
Sbjct: 362 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE---QEEMMQEQEEKMGEQEE 418
Query: 130 KIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHD 189
K+ + + +K R E+ ++E+E + R+ + + E + ++ + +
Sbjct: 419 KMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCE 478
Query: 190 EEQKVWD-EEIDDDDDDNCNNDEDEVRVIEFK-KKHEEVSQFKEE 232
+E K+ + EE ++ E ++R E K ++ EE+ Q +EE
Sbjct: 479 QEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 523
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 44.7 bits (104), Expect = 1e-04
Identities = 39/175 (22%), Positives = 80/175 (45%), Gaps = 11/175 (6%)
Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSA----DEMTFREGH 126
QEE+ + Q + E KM ++ EEK+ K + QE +E +
Sbjct: 435 QEEKIREQEEKI--REQEKKMWRQ--EEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEE 490
Query: 127 QW-EKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLH 185
W +K + ++IR+Q+E++ Q K E E++ + + + R+ +
Sbjct: 491 IWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREE 550
Query: 186 SKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFK--KKHEEVSQFKEEGDASED 238
K E++K+W+EE + +D E+++R E K ++ E++ + +E+ E+
Sbjct: 551 EKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEE 605
Score = 41.6 bits (96), Expect = 8e-04
Identities = 40/187 (21%), Positives = 83/187 (44%), Gaps = 19/187 (10%)
Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130
+EE+R+ Q EDKM ++ EEK + + + QE E + Q EK
Sbjct: 561 EEEKRQEQ---------EDKMWRQ--EEK---IREQEEKVWRQEEKIREQEEKRQEQEEK 606
Query: 131 IPLSGSNQEIRRQKERITEQP--LKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKH 188
+ ++IR Q+E+I EQ ++E+E++ R+ + + E +G ++ +
Sbjct: 607 --MWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQ 664
Query: 189 DEEQKVW-DEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQ 247
++E+ +W EE + + E+++R E + +E +++E E +
Sbjct: 665 EQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 724
Query: 248 AVTPDEQ 254
+ E+
Sbjct: 725 KMRRQEE 731
Score = 41.2 bits (95), Expect = 0.001
Identities = 41/211 (19%), Positives = 102/211 (48%), Gaps = 17/211 (8%)
Query: 88 EDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKERI 147
E+K+ K+ EEK++ + I + + +E +R+ + + +E ++E+I
Sbjct: 502 EEKIRKQ--EEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKI 559
Query: 148 TEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQA-DMLHSKHDEEQKVW-DEEIDDDDDD 205
E+ ++E+++ + + E E +R+ + + + ++E+K+W EE + ++
Sbjct: 560 WEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEE 619
Query: 206 NCNNDEDEVRVIEFK-KKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSDIS 264
E+++R E K ++ EE++Q +EE ++ + + +++ T+ ++ +
Sbjct: 620 KIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKM--CEQEEKMQEQEETMWRQEEKI 677
Query: 265 RNAYSRYNTISYRKIRKGNTKQRIDEFESMM 295
R +KIR+ +++I E E MM
Sbjct: 678 RE--------QEKKIRE--QEEKIREQEEMM 698
Score = 40.0 bits (92), Expect = 0.002
Identities = 37/198 (18%), Positives = 95/198 (47%), Gaps = 17/198 (8%)
Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130
+EE+R+ Q M E+K+ + +E+++ + + + + +E +R Q EK
Sbjct: 468 EEEKRQEQEEMW---RQEEKI---HEQEEIWRQKEKMHEQEEKIRKQEEKVWR---QEEK 518
Query: 131 IPLSGSNQEIRRQKERI--TEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKH 188
I ++IR Q+E++ E+ ++E+E+ R+ + E W ++ Q D + +
Sbjct: 519 I--REQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE 576
Query: 189 D----EEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSA 244
+ +E+KVW +E + + +++E + +K E+ + +E+ + +
Sbjct: 577 EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIR 636
Query: 245 SSQAVTPDEQPTLGKKSD 262
+ +T +++ +G++ +
Sbjct: 637 EQEEMTQEQEEKMGEQEE 654
Score = 39.3 bits (90), Expect = 0.004
Identities = 51/272 (18%), Positives = 112/272 (41%), Gaps = 31/272 (11%)
Query: 36 QQTITKISEELTDVDSPL-PHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKE 94
Q + ++ E D+ S L ++ LE AL+ + ++++ +++ KE
Sbjct: 150 QHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKA--------DRYIEELTKE 201
Query: 95 NPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKER----ITEQ 150
L + ITD L+E +A + + EK + + +E++R+ ER + +Q
Sbjct: 202 RDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQ 261
Query: 151 PLKEEEDEDRKNKGHQAAEIEW------LGFRKPSQADMLHSKHDEEQKVWDEEIDDDDD 204
L+ E D K +A+++ L R Q + + +E+ + W+E+I + +
Sbjct: 262 QLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQ-EQE 320
Query: 205 DNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSDIS 264
+ E+++R E K + +E +++E + + + E+ K+ +
Sbjct: 321 EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 380
Query: 265 RNAYSRYNTISYRKIRKGNTKQRIDEFESMMH 296
R + +++I E E MH
Sbjct: 381 RQEEMMW-----------EKEEKIRELEEKMH 401
Score = 38.9 bits (89), Expect = 0.006
Identities = 37/190 (19%), Positives = 82/190 (43%), Gaps = 24/190 (12%)
Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130
+EE+ + Q M+ + + L+E E+ + I + + +++ +E Q ++
Sbjct: 375 KEEKMRRQEEMMWEKEEKIRELEEKMHEQ-----EKIREQEEKRQEEEKIREQEKRQEQE 429
Query: 131 IPLSGSNQEIRRQKERITEQPLK--------EEEDEDRKNKGHQAAEIEWLGFRKPS--- 179
+ ++IR Q+E+I EQ K E+++ R+ + Q E W K
Sbjct: 430 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQE 489
Query: 180 ----QADMLHSKHD----EEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKE 231
Q + +H + + +E+KVW +E + + +++E + +K E+ ++E
Sbjct: 490 EIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWRE 549
Query: 232 EGDASEDSPL 241
E E +
Sbjct: 550 EEKMHEQEKI 559
Score = 38.1 bits (87), Expect = 0.009
Identities = 38/173 (21%), Positives = 75/173 (43%), Gaps = 25/173 (14%)
Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130
QEE+R+ Q + + + +E +E+ + + + QE E + G Q EK
Sbjct: 596 QEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655
Query: 131 I-----PLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLH 185
+ + + + RQ+E+I EQ K E E++ + Q +M+
Sbjct: 656 MCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIRE----------------QEEMMQ 699
Query: 186 SKHDEEQKVWD-EEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASE 237
++E+K+W+ EE + ++ E+++R E K +EV ++E E
Sbjct: 700 ---EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 44.7 bits (104), Expect = 1e-04
Identities = 37/193 (19%), Positives = 88/193 (45%), Gaps = 13/193 (6%)
Query: 69 GSQEERRKLQGNMLLNSSMEDKMLKENP-----EEKLFIVHKAITDLSLQETSADEMTFR 123
G QEE+ + Q + E+++ K+ EE++ + + + Q +E +
Sbjct: 223 GEQEEQMRKQEEQM--GEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLK 280
Query: 124 EGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADM 183
+ Q E+ +G +E R++E + ++E+E++ R+ + + E +G ++ +
Sbjct: 281 QKEQTEQEEQTGEQEEQMREQE----EQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQ 336
Query: 184 LHSKHDEEQKVW-DEEIDDDDDDNCNNDEDEVRVIEFK-KKHEEVSQFKEEGDASEDSPL 241
++++++W EE + ++ E++VR E + +K EE + +EE ++ +
Sbjct: 337 KEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQM 396
Query: 242 SSASSQAVTPDEQ 254
Q EQ
Sbjct: 397 GEQKEQMGEQKEQ 409
Score = 32.0 bits (71), Expect = 0.67
Identities = 23/143 (16%), Positives = 62/143 (43%), Gaps = 1/143 (0%)
Query: 113 QETSADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEW 172
QE E + G Q E++ + ++ R E+ + E+E++ +K + + E
Sbjct: 197 QEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQ 256
Query: 173 LGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFK-KKHEEVSQFKE 231
+ ++ + ++E+++ ++ + ++ E+++R E + ++ EE + +E
Sbjct: 257 MRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQE 316
Query: 232 EGDASEDSPLSSASSQAVTPDEQ 254
E ++ + Q EQ
Sbjct: 317 EQMREQEEQMGKQEEQMWEQKEQ 339
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 44.3 bits (103), Expect = 1e-04
Identities = 60/286 (20%), Positives = 114/286 (39%), Gaps = 34/286 (11%)
Query: 7 DRIQPHIM---TDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLE 63
D ++P I ++ P ++ ++PP+ + SEEL P P S E
Sbjct: 176 DALKPQISDSESEEPPRHQASDSENEEPPK--PRMSDSESEEL-----PKPQVSDSESEE 228
Query: 64 GALTKGSQEERRKLQGNMLLNSSMEDKMLKE-NPEEKLFIVHKAITDLSLQETSADEMTF 122
+ S E +L + +S ED + + E + I+D ++ ++ +
Sbjct: 229 PPRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASD 288
Query: 123 REGHQWEKIPLSGSNQEIRRQ---KERITE------QPLKEEEDEDRKNKGHQAAEIEWL 173
E + K +S S E ++ + TE Q + ++D DR+NKG E++
Sbjct: 289 SENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDT-EMQND 347
Query: 174 GFRKPSQADM--LHSKHDEEQKVWDEEIDDDDDDNCNNDED----EVRVIEFKKKHEEVS 227
F S D HS EE++ +++D D+D+ +E + V+ + E+ S
Sbjct: 348 SFHSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKAS 407
Query: 228 QFK-------EEGDASEDSPLSSASSQAVTPDEQPTLGKKSDISRN 266
K ++ D+ S S + + D + GK+ +N
Sbjct: 408 AKKSRVVSDADDSDSDAVSDKSGKREKTIASDSEEEAGKELSDKKN 453
>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
sapiens]
Length = 1251
Score = 43.9 bits (102), Expect = 2e-04
Identities = 39/178 (21%), Positives = 79/178 (44%), Gaps = 5/178 (2%)
Query: 80 NMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQE 139
++L +E ++ E E H+ ++ S Q T E EK+P S E
Sbjct: 293 SILPGGQVEPDLVLEEVEPPWEDAHQDVST-SPQGTEVVPAYEEENKAVEKMPRELSRIE 351
Query: 140 IRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDE-- 197
++ E E+ +EEE+E+ + + +G + S+ D + +QK+W+E
Sbjct: 352 EEKEDEEEEEEEEEEEEEEEVTEVLLDSCVVSQVGVGQ-SEEDGTRPQSTSDQKLWEEVG 410
Query: 198 -EIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQ 254
E + ++ + +EV E +K+ ++ ++ KEE +A ++ S + P+ Q
Sbjct: 411 EEAKKEAEEKAKEEAEEVAEEEAEKEPQDWAETKEEPEAEAEAASSGVPATKQHPEVQ 468
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 43.9 bits (102), Expect = 2e-04
Identities = 57/294 (19%), Positives = 118/294 (40%), Gaps = 38/294 (12%)
Query: 16 DVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERR 75
D P +++ + D+ E+ + S ++T SP+P E + +T+ +E +
Sbjct: 278 DGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSPVPQ---EEHSDPEMTEEEKEYQM 334
Query: 76 KLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSG 135
L MLL ++L + +E+++ V K D + T A + + G
Sbjct: 335 MLLTKMLLT-----EILLDVTDEEIYYVAK---DAHRKATKAPAKQLAQSSALASLTGLG 386
Query: 136 ------SNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHD 189
S + +R +E + +DE+ +++ Q E W RK + +LH K
Sbjct: 387 GLGGYGSGDSEDERSDRGSES--SDTDDEELRHRIRQKQEAFW---RKEKEQQLLHDKQM 441
Query: 190 EEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPL-------- 241
EE+K E + + ++ + +++ + ++E ++ +V K+ S L
Sbjct: 442 EEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKE 501
Query: 242 --------SSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQR 287
S +SS + T S +S ++YS + S R + K++
Sbjct: 502 KEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRK 555
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 43.9 bits (102), Expect = 2e-04
Identities = 57/294 (19%), Positives = 118/294 (40%), Gaps = 38/294 (12%)
Query: 16 DVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERR 75
D P +++ + D+ E+ + S ++T SP+P E + +T+ +E +
Sbjct: 278 DGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSPVPQ---EEHSDPEMTEEEKEYQM 334
Query: 76 KLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSG 135
L MLL ++L + +E+++ V K D + T A + + G
Sbjct: 335 MLLTKMLLT-----EILLDVTDEEIYYVAK---DAHRKATKAPAKQLAQSSALASLTGLG 386
Query: 136 ------SNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHD 189
S + +R +E + +DE+ +++ Q E W RK + +LH K
Sbjct: 387 GLGGYGSGDSEDERSDRGSES--SDTDDEELRHRIRQKQEAFW---RKEKEQQLLHDKQM 441
Query: 190 EEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPL-------- 241
EE+K E + + ++ + +++ + ++E ++ +V K+ S L
Sbjct: 442 EEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKE 501
Query: 242 --------SSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQR 287
S +SS + T S +S ++YS + S R + K++
Sbjct: 502 KEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRK 555
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 43.5 bits (101), Expect = 2e-04
Identities = 37/193 (19%), Positives = 85/193 (44%), Gaps = 34/193 (17%)
Query: 85 SSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEI---- 140
+ +E + +E E++L H+ + D L+E ++ F + + + GS +E
Sbjct: 568 NGLEKDLDEEGSEKEL---HENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDS 624
Query: 141 -RRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEI 199
+++E T + + ++E ++++++ E+ + AD + D ++K+++E
Sbjct: 625 DEKEEEEDTYEKVFDDESDEKEDE-------EYADEKGLEAADKKAEEGDADEKLFEESD 677
Query: 200 DDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDAS-------------------EDSP 240
D +D+D + ++ F+ F EE D+S E+ P
Sbjct: 678 DKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLGGFGSVEEGP 737
Query: 241 LSSASSQAVTPDE 253
LS+ SS ++ D+
Sbjct: 738 LSTGSSFILSSDD 750
Score = 42.7 bits (99), Expect = 4e-04
Identities = 48/206 (23%), Positives = 96/206 (46%), Gaps = 17/206 (8%)
Query: 61 SLEGALTKGSQEERRKLQGNM--LLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSAD 118
S EG +GS+E+ K + L N E+ + KE+ ++ + ++ ++ + S +
Sbjct: 485 SEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDD---LNKESEEEVGPTKESEE 541
Query: 119 EMTFREGHQ--WEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFR 176
+ + +E + EK GS +E +E E+ L EE E ++ E+E
Sbjct: 542 DDSEKESDEDCSEKQSEDGSEREF---EENGLEKDLDEEGSEKELHENVLDKELE----- 593
Query: 177 KPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDAS 236
+ ++ + D +KV DEE + + D ++DE E ++K ++ S KE+ + +
Sbjct: 594 -ENDSENSEFEDDGSEKVLDEEGSEREFDE-DSDEKEEEEDTYEKVFDDESDEKEDEEYA 651
Query: 237 EDSPLSSASSQAVTPDEQPTLGKKSD 262
++ L +A +A D L ++SD
Sbjct: 652 DEKGLEAADKKAEEGDADEKLFEESD 677
>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 43.5 bits (101), Expect = 2e-04
Identities = 37/193 (19%), Positives = 85/193 (44%), Gaps = 34/193 (17%)
Query: 85 SSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEI---- 140
+ +E + +E E++L H+ + D L+E ++ F + + + GS +E
Sbjct: 568 NGLEKDLDEEGSEKEL---HENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDS 624
Query: 141 -RRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEI 199
+++E T + + ++E ++++++ E+ + AD + D ++K+++E
Sbjct: 625 DEKEEEEDTYEKVFDDESDEKEDE-------EYADEKGLEAADKKAEEGDADEKLFEESD 677
Query: 200 DDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDAS-------------------EDSP 240
D +D+D + ++ F+ F EE D+S E+ P
Sbjct: 678 DKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLGGFGSVEEGP 737
Query: 241 LSSASSQAVTPDE 253
LS+ SS ++ D+
Sbjct: 738 LSTGSSFILSSDD 750
Score = 42.7 bits (99), Expect = 4e-04
Identities = 48/206 (23%), Positives = 96/206 (46%), Gaps = 17/206 (8%)
Query: 61 SLEGALTKGSQEERRKLQGNM--LLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSAD 118
S EG +GS+E+ K + L N E+ + KE+ ++ + ++ ++ + S +
Sbjct: 485 SEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDD---LNKESEEEVGPTKESEE 541
Query: 119 EMTFREGHQ--WEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFR 176
+ + +E + EK GS +E +E E+ L EE E ++ E+E
Sbjct: 542 DDSEKESDEDCSEKQSEDGSEREF---EENGLEKDLDEEGSEKELHENVLDKELE----- 593
Query: 177 KPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDAS 236
+ ++ + D +KV DEE + + D ++DE E ++K ++ S KE+ + +
Sbjct: 594 -ENDSENSEFEDDGSEKVLDEEGSEREFDE-DSDEKEEEEDTYEKVFDDESDEKEDEEYA 651
Query: 237 EDSPLSSASSQAVTPDEQPTLGKKSD 262
++ L +A +A D L ++SD
Sbjct: 652 DEKGLEAADKKAEEGDADEKLFEESD 677
>gi|4506467 radixin [Homo sapiens]
Length = 583
Score = 43.5 bits (101), Expect = 2e-04
Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 12/110 (10%)
Query: 185 HSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSA 244
H +HDE E+ ++ N ++E+ RV E +K Q + + S L+ A
Sbjct: 486 HDEHDENNAEASAELSNEGVMNHRSEEE--RVTETQKNERVKKQLQ-----ALSSELAQA 538
Query: 245 SSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESM 294
+ + R+ Y + R+IR+GNTKQRIDEFE+M
Sbjct: 539 RDETKKTQNDVLHAENVKAGRDKYK-----TLRQIRQGNTKQRIDEFEAM 583
>gi|4504487 histidine rich calcium binding protein precursor [Homo
sapiens]
Length = 699
Score = 43.5 bits (101), Expect = 2e-04
Identities = 35/130 (26%), Positives = 52/130 (40%), Gaps = 4/130 (3%)
Query: 111 SLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEI 170
S Q+ DE+ E H I G E E+ +EEE+E GHQA
Sbjct: 159 SHQDEDEDEVVSSEHHH--HILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRH 216
Query: 171 EWLGFRKPSQADMLHSKH--DEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQ 228
G + H H + +E+ DDDDDD+ ++D+D+V + + H
Sbjct: 217 RGHGSEEDEDVSDGHHHHGPSHRHQGHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGH 276
Query: 229 FKEEGDASED 238
EE + D
Sbjct: 277 GIEEDEDVSD 286
Score = 32.3 bits (72), Expect = 0.52
Identities = 24/104 (23%), Positives = 44/104 (42%), Gaps = 19/104 (18%)
Query: 137 NQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWD 196
+ E Q E+ T +++EDE+ + +GH S + EE++ D
Sbjct: 498 DDESSEQGEKGTHHGSRDQEDEEDEEEGHGL------------------SLNQEEEEEED 539
Query: 197 EEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSP 240
+E +++++D +E H E + +EEG ED P
Sbjct: 540 KEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEEEG-LEEDEP 582
Score = 29.6 bits (65), Expect = 3.3
Identities = 28/146 (19%), Positives = 59/146 (40%), Gaps = 13/146 (8%)
Query: 117 ADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQ-----PLKEEEDEDRKNKGHQAAEIE 171
+DE F++ ++ E +P ++ R + E ++ + P + +D + Q I+
Sbjct: 401 SDEEDFQDEYKTE-VPHHHHHRVPREEDEEVSAELGHQAPSHRQSHQDEETGHGQRGSIK 459
Query: 172 WLGFRKPSQA---DMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQ 228
+ P D H + D+ + EE + ++D + ++DE K H
Sbjct: 460 EMSHHPPGHTVVKDRSHLRKDDSE----EEKEKEEDPGSHEEDDESSEQGEKGTHHGSRD 515
Query: 229 FKEEGDASEDSPLSSASSQAVTPDEQ 254
++E D E LS + D++
Sbjct: 516 QEDEEDEEEGHGLSLNQEEEEEEDKE 541
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 43.1 bits (100), Expect = 3e-04
Identities = 45/172 (26%), Positives = 82/172 (47%), Gaps = 17/172 (9%)
Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITD----LSLQETSADEMTFREGH 126
QEE+ Q + E+KM ++ EEK+ + I + + QE E + G
Sbjct: 500 QEEKMHDQEEKI--REQEEKMWRQ--EEKIREQEEKIREQEEKIREQEEMMQEQEEKMGE 555
Query: 127 QWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHS 186
Q EK+ +++RRQ+E+I EQ EE+ ++K K + E W K + + +
Sbjct: 556 QEEKMQ---EQEKMRRQEEKIREQ---EEKIREQKEKIREQEEKIWEQEEKIREQEEM-- 607
Query: 187 KHDEEQKVWD-EEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASE 237
++E+K+W+ EE + ++ E+++R E K +EV ++E E
Sbjct: 608 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 659
Score = 38.1 bits (87), Expect = 0.009
Identities = 43/208 (20%), Positives = 94/208 (45%), Gaps = 20/208 (9%)
Query: 36 QQTITKISEELTDVDSPL-PHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKE 94
Q + ++ E D+ S L ++ LE AL+ + ++++ +++ KE
Sbjct: 150 QHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKA--------DRYIEELTKE 201
Query: 95 NPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKER----ITEQ 150
L + ITD L+E +A + + EK + + +E++R+ ER + +Q
Sbjct: 202 RDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQ 261
Query: 151 PLKEEEDEDRKNKGHQAAEIEW------LGFRKPSQADMLHSKHDEEQKVWDEEIDDDDD 204
L+ E D K +A+++ L R Q + + +E+ + W+E+I + +
Sbjct: 262 QLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQ-EQE 320
Query: 205 DNCNNDEDEVRVIEFKKKHEEVSQFKEE 232
+ E+++R E K + +E +++E
Sbjct: 321 EKIREQEEKIREQEEKMRRQEEMMWEKE 348
Score = 35.0 bits (79), Expect = 0.079
Identities = 31/161 (19%), Positives = 69/161 (42%), Gaps = 17/161 (10%)
Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130
QEE+ + Q M+ E+KM ++ EE ++ ++M E WEK
Sbjct: 333 QEEKMRRQEEMMWEK--EEKMRRQ--EEMMW-------------EKEEKMRRLEEMMWEK 375
Query: 131 IPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDE 190
+E ++E+I EQ K +E+E + + + + + ++ + ++
Sbjct: 376 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 435
Query: 191 EQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKE 231
E+K+W +E + + +E E ++ E++ + +E
Sbjct: 436 EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE 476
Score = 34.7 bits (78), Expect = 0.10
Identities = 32/153 (20%), Positives = 71/153 (46%), Gaps = 15/153 (9%)
Query: 88 EDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKERI 147
++K+ K+ EEK++ + + D QE E + Q EKI ++IR Q+E+I
Sbjct: 487 QEKIRKQ--EEKVWRQEEKMHD---QEEKIREQEEKMWRQEEKI--REQEEKIREQEEKI 539
Query: 148 TEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSK--------HDEEQKVWDEEI 199
EQ +E E++ + + + + R+ + K ++E+K+W++E
Sbjct: 540 REQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEE 599
Query: 200 DDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEE 232
+ + +++E + +K E+ + +E+
Sbjct: 600 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 632
Score = 32.0 bits (71), Expect = 0.67
Identities = 39/170 (22%), Positives = 78/170 (45%), Gaps = 18/170 (10%)
Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPE-----EKLFIVHKAITDLSLQETSADEMTFREG 125
+EE+R+ Q M +++ ++E E EK+ K + QE +
Sbjct: 454 EEEKRQEQEEMW----RQEEKIREQEEIWRQKEKMHEQEK----IRKQEEKVWRQEEKMH 505
Query: 126 HQWEKIPLSGSNQEIRRQKERITEQP--LKEEEDEDRKNKGHQAAEIEWLGFRKPSQADM 183
Q EKI +++ RQ+E+I EQ ++E+E++ R+ + + E +G ++ +
Sbjct: 506 DQEEKI--REQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ 563
Query: 184 LHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFK-KKHEEVSQFKEE 232
+ EE+ EE + + E+++ E K ++ EE+ Q +EE
Sbjct: 564 EKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEE 613
Score = 28.9 bits (63), Expect = 5.7
Identities = 29/118 (24%), Positives = 57/118 (48%), Gaps = 19/118 (16%)
Query: 69 GSQEERRKLQGNMLLNSS----MEDKMLKENP-----EEKLFIVHKAITDLSLQETSADE 119
G QEE+ + Q M E+K+ ++ EEK++ + I + QE E
Sbjct: 554 GEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIRE---QEEMMQE 610
Query: 120 MTFREGHQWEKI-----PLSGSNQEIRRQKERITEQP--LKEEEDEDRKNKGHQAAEI 170
+ Q EK+ + +++RRQ+E++ EQ L+++E++ ++++ H A I
Sbjct: 611 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 43.1 bits (100), Expect = 3e-04
Identities = 57/221 (25%), Positives = 92/221 (41%), Gaps = 38/221 (17%)
Query: 30 KPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMED 89
KPP NG Q K S+EL + L H P E + GS+ +R + S E
Sbjct: 532 KPPMNGYQ---KFSQELLS-NGELNHL---PLKERMVEIGSRWQR-------ISQSQKEH 577
Query: 90 KMLKENPEEKLFIVHKAITDLSLQETSADEMTFRE---GHQWEKIPLSGSNQEIRRQK-E 145
++K + VH + SL + D ++E + L G N + R +
Sbjct: 578 YKKLAEEQQKQYKVHLDLWVKSL--SPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQ 635
Query: 146 RITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDD 205
+E +EEDED +++ + + E G D S ++E + DE +DD+D+
Sbjct: 636 SKSESEEDDEEDEDDEDEDEEEEDDE-NGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 694
Query: 206 NCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASS 246
+ + D+DE +E + SE S SS+SS
Sbjct: 695 DDDEDDDE-----------------DEDNESEGSSSSSSSS 718
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 43.1 bits (100), Expect = 3e-04
Identities = 57/221 (25%), Positives = 92/221 (41%), Gaps = 38/221 (17%)
Query: 30 KPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMED 89
KPP NG Q K S+EL + L H P E + GS+ +R + S E
Sbjct: 532 KPPMNGYQ---KFSQELLS-NGELNHL---PLKERMVEIGSRWQR-------ISQSQKEH 577
Query: 90 KMLKENPEEKLFIVHKAITDLSLQETSADEMTFRE---GHQWEKIPLSGSNQEIRRQK-E 145
++K + VH + SL + D ++E + L G N + R +
Sbjct: 578 YKKLAEEQQKQYKVHLDLWVKSL--SPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQ 635
Query: 146 RITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDD 205
+E +EEDED +++ + + E G D S ++E + DE +DD+D+
Sbjct: 636 SKSESEEDDEEDEDDEDEDEEEEDDE-NGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 694
Query: 206 NCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASS 246
+ + D+DE +E + SE S SS+SS
Sbjct: 695 DDDEDDDE-----------------DEDNESEGSSSSSSSS 718
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 43.1 bits (100), Expect = 3e-04
Identities = 57/221 (25%), Positives = 92/221 (41%), Gaps = 38/221 (17%)
Query: 30 KPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMED 89
KPP NG Q K S+EL + L H P E + GS+ +R + S E
Sbjct: 569 KPPMNGYQ---KFSQELLS-NGELNHL---PLKERMVEIGSRWQR-------ISQSQKEH 614
Query: 90 KMLKENPEEKLFIVHKAITDLSLQETSADEMTFRE---GHQWEKIPLSGSNQEIRRQK-E 145
++K + VH + SL + D ++E + L G N + R +
Sbjct: 615 YKKLAEEQQKQYKVHLDLWVKSL--SPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQ 672
Query: 146 RITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDD 205
+E +EEDED +++ + + E G D S ++E + DE +DD+D+
Sbjct: 673 SKSESEEDDEEDEDDEDEDEEEEDDE-NGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 731
Query: 206 NCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASS 246
+ + D+DE +E + SE S SS+SS
Sbjct: 732 DDDEDDDE-----------------DEDNESEGSSSSSSSS 755
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 42.4 bits (98), Expect = 5e-04
Identities = 44/209 (21%), Positives = 80/209 (38%), Gaps = 32/209 (15%)
Query: 73 ERRKLQGNMLLNSSMEDKMLKEN---PEEKLFIVHKAITDLSLQETSADEMTFREGHQWE 129
E +K+Q E+KM +E EK K + ++M +E + WE
Sbjct: 428 EEKKMQEQEKKTRDQEEKMQEEERIREREK-----KMREEEETMREQEEKMQKQEENMWE 482
Query: 130 KIPLSGSNQEIRRQKERITEQPLKEEEDE---DRKNKGHQAAEI------EWLGFRKPSQ 180
+ Q + QKE++ EQ +E++E +++ K E+ W + Q
Sbjct: 483 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 542
Query: 181 ADML----HSKHDEEQKVWDEEIDDD-----------DDDNCNNDEDEVRVIEFKKKHEE 225
D + D+EQK+WD+E + D + +E+ +R E K + EE
Sbjct: 543 EDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE 602
Query: 226 VSQFKEEGDASEDSPLSSASSQAVTPDEQ 254
++E E + + E+
Sbjct: 603 EMMREQEEKMQEQEEKMQEQEEKMWEQEE 631
Score = 40.0 bits (92), Expect = 0.002
Identities = 42/186 (22%), Positives = 82/186 (44%), Gaps = 27/186 (14%)
Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130
QEE+ Q L E KM ++ EEK++ K + + +E E RE
Sbjct: 291 QEEKMWRQEERL--REQEGKMREQ--EEKMWRQEKRLREQE-KELREQEKELRE------ 339
Query: 131 IPLSGSNQEIRRQKERITEQPLK--EEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKH 188
+E+R Q+E++ EQ K E+E++ R+ + + E L ++ +
Sbjct: 340 ------QKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 393
Query: 189 DEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQA 248
D+E+++W++ D+ E+ +R E +K E+V + +EE E + +
Sbjct: 394 DQEERMWEQ------DERLREKEERMR--EQEKMWEQVEKMREEKKMQEQEKKTRDQEEK 445
Query: 249 VTPDEQ 254
+ +E+
Sbjct: 446 MQEEER 451
Score = 38.9 bits (89), Expect = 0.006
Identities = 34/162 (20%), Positives = 66/162 (40%), Gaps = 12/162 (7%)
Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130
+E +K++ + E+KM +E E+ K + ++M +E WE+
Sbjct: 592 REREKKMREEEEMMREQEEKM-QEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 650
Query: 131 IPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDE 190
Q + QKE++ E +E++ K + E W Q M ++
Sbjct: 651 EEKMWEQQRLPEQKEKLWEHEKMQEQE-----KMQEQEEKIW------EQEKMEKKTQEQ 699
Query: 191 EQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEE 232
E+K WD+E +++ ++ E ++ EE Q +EE
Sbjct: 700 EKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEE 741
Score = 34.7 bits (78), Expect = 0.10
Identities = 36/190 (18%), Positives = 77/190 (40%), Gaps = 23/190 (12%)
Query: 66 LTKGSQEERRKL--QGNMLLNSSMEDKMLKENPEEKLFIVH--KAITDLSLQETSADEMT 121
+ K +QE+ +K Q M SM ++ K EE++ K + +EM
Sbjct: 692 MEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMW 751
Query: 122 FREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEED---EDRKNKGHQAAEIEWLGFRKP 178
+E WE+ Q + QKE++ E +E++ E + Q ++ +
Sbjct: 752 EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMR 811
Query: 179 SQADMLHSKHD----EEQKVWDEE------------IDDDDDDNCNNDEDEVRVIEFKKK 222
Q + + + + +E+K+W +E ++ ++ E+++R E K +
Sbjct: 812 GQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMR 871
Query: 223 HEEVSQFKEE 232
+E ++E
Sbjct: 872 GQEEKMREQE 881
Score = 33.9 bits (76), Expect = 0.18
Identities = 36/189 (19%), Positives = 78/189 (41%), Gaps = 31/189 (16%)
Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130
QEE+ Q L ++K ++E E+K+ + + + + +E + WE+
Sbjct: 367 QEEKMWRQEERLWE---QEKQMREQ-EQKMRDQEERMWEQDERLREKEERMREQEKMWEQ 422
Query: 131 IPLSGSNQEIRRQKERITEQPLKEEEDE---DRKNKGHQAAEI----------------- 170
+ ++++ Q+++ +Q K +E+E +R+ K + E
Sbjct: 423 VEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE 482
Query: 171 ----EWLGFRKPSQADML---HSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKH 223
EW R P Q + L ++E+K+W++E D + E ++ E ++
Sbjct: 483 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 542
Query: 224 EEVSQFKEE 232
E+ +EE
Sbjct: 543 EDQMWEQEE 551
Score = 32.7 bits (73), Expect = 0.39
Identities = 28/130 (21%), Positives = 58/130 (44%), Gaps = 11/130 (8%)
Query: 71 QEERRKLQGNMLLNSSMEDKMLKEN--PEEKLFIVHKAITDLSLQETSADEMTFREGHQW 128
QE+ K+ E+KM ++ PE+K K +QE ++M +E W
Sbjct: 634 QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQK----EKLWEHEKMQEQ--EKMQEQEEKIW 687
Query: 129 EKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKH 188
E+ + QE Q+++ +Q EE+ R+ + E E + ++ +
Sbjct: 688 EQEKMEKKTQE---QEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQ 744
Query: 189 DEEQKVWDEE 198
++E+++W++E
Sbjct: 745 EQEEEMWEQE 754
Score = 30.4 bits (67), Expect = 2.0
Identities = 27/134 (20%), Positives = 64/134 (47%), Gaps = 11/134 (8%)
Query: 71 QEERRKLQGNMLLNSSMEDKMLKENP----EEKLFIVHKAITDLSLQETSADEMTFREGH 126
QEE+ + Q M E KM ++ E++++ + + D + +E ++
Sbjct: 516 QEEKIRDQEEMW---GQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQ 572
Query: 127 QWEKIPLSGSNQEIRRQKERITEQP--LKEEEDEDRKNKGHQAAEIEWLGFRKPSQADML 184
+ EK + +E R++ER+ E+ ++EEE+ R+ + + E + ++ +
Sbjct: 573 EQEK--KTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQE 630
Query: 185 HSKHDEEQKVWDEE 198
++E+K+W++E
Sbjct: 631 EKMQEQEEKMWEQE 644
Score = 29.6 bits (65), Expect = 3.3
Identities = 30/168 (17%), Positives = 77/168 (45%), Gaps = 4/168 (2%)
Query: 88 EDKMLKENPEEKLFIVHKAITDLSLQ-ETSADEMTFREGHQWEKIPLSGSNQEIRRQKER 146
ED+M ++ EEK+ + + D + E E + Q EK+ +E R +K R
Sbjct: 543 EDQMWEQ--EEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRE-REKKMR 599
Query: 147 ITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDN 206
E+ ++E+E++ ++ + + E + ++ + ++E+K+W++E +
Sbjct: 600 EEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 659
Query: 207 CNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQ 254
++++ E ++ E++ + +E+ E + + T D++
Sbjct: 660 LPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQE 707
>gi|161702986 ezrin [Homo sapiens]
Length = 586
Score = 42.0 bits (97), Expect = 7e-04
Identities = 63/241 (26%), Positives = 103/241 (42%), Gaps = 48/241 (19%)
Query: 68 KGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQ 127
K +QEE +L+ D+M +E+L +A+ + QE A E+
Sbjct: 380 KRAQEEAERLEA---------DRMAALRAKEEL--ERQAVDQIKSQEQLAAELA----EY 424
Query: 128 WEKIPLSGSNQEIRRQKERITEQ---PLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADML 184
KI L +E RR+KE E+ KE +D+ K K E+ + P +
Sbjct: 425 TAKIALL---EEARRRKEDEVEEWQHRAKEAQDDLVKTK----EELHLVMTAPPPPPPPV 477
Query: 185 HS--KHDEEQKVWDEEIDDD------DDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDAS 236
+ + ++ + DE + + +D +E + I +K+E V +
Sbjct: 478 YEPVSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQR-------- 529
Query: 237 EDSPLSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISY---RKIRKGNTKQRIDEFES 293
+ LSS SQA +++ +DI N R Y R+IR+GNTKQRIDEFE+
Sbjct: 530 QLLTLSSELSQARDENKRT----HNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEA 585
Query: 294 M 294
+
Sbjct: 586 L 586
>gi|21614499 ezrin [Homo sapiens]
Length = 586
Score = 42.0 bits (97), Expect = 7e-04
Identities = 63/241 (26%), Positives = 103/241 (42%), Gaps = 48/241 (19%)
Query: 68 KGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQ 127
K +QEE +L+ D+M +E+L +A+ + QE A E+
Sbjct: 380 KRAQEEAERLEA---------DRMAALRAKEEL--ERQAVDQIKSQEQLAAELA----EY 424
Query: 128 WEKIPLSGSNQEIRRQKERITEQ---PLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADML 184
KI L +E RR+KE E+ KE +D+ K K E+ + P +
Sbjct: 425 TAKIALL---EEARRRKEDEVEEWQHRAKEAQDDLVKTK----EELHLVMTAPPPPPPPV 477
Query: 185 HS--KHDEEQKVWDEEIDDD------DDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDAS 236
+ + ++ + DE + + +D +E + I +K+E V +
Sbjct: 478 YEPVSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQR-------- 529
Query: 237 EDSPLSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISY---RKIRKGNTKQRIDEFES 293
+ LSS SQA +++ +DI N R Y R+IR+GNTKQRIDEFE+
Sbjct: 530 QLLTLSSELSQARDENKRT----HNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEA 585
Query: 294 M 294
+
Sbjct: 586 L 586
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 42.0 bits (97), Expect = 7e-04
Identities = 40/202 (19%), Positives = 83/202 (41%), Gaps = 31/202 (15%)
Query: 71 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130
++ER K +G +L S E + E L ++ ++ +++ + E + +K
Sbjct: 397 RKERLKKEGKLLTKSQRE---ARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKK 453
Query: 131 IPLSGSNQEIRRQKE-----RITEQ----------PLKEEEDEDRKNKGHQAAEIEWLGF 175
IP ++E+ E + EQ P++ EE+ED ++ G +W
Sbjct: 454 IPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLD----DWEAM 509
Query: 176 RKPSQADMLHSKH---------DEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEV 226
+ + + +EE++ +EE +D++ + +E E E ++ E+V
Sbjct: 510 ASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKV 569
Query: 227 SQFKEEGDASEDSPLSSASSQA 248
S K+ G + P SS +
Sbjct: 570 SDEKDSGKTLDKKPSKEMSSDS 591
Score = 29.3 bits (64), Expect = 4.4
Identities = 27/138 (19%), Positives = 65/138 (47%), Gaps = 12/138 (8%)
Query: 137 NQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWL--GFRKPSQADMLHSKHDEEQ-- 192
N+ +++K++ ++ KEE+++++K KG A ++ + K + + + +EE+
Sbjct: 309 NEGDKKKKDKKKKKGEKEEKEKEKK-KGPSKATVKAMQEALAKLKEEEERQKREEEERIK 367
Query: 193 -------KVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSAS 245
K +EE + + +++ R KK+ + +++ + E A ++ L
Sbjct: 368 RLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQ 427
Query: 246 SQAVTPDEQPTLGKKSDI 263
+Q V + +L KK I
Sbjct: 428 AQGVEVPSKDSLPKKRPI 445
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 41.2 bits (95), Expect = 0.001
Identities = 36/160 (22%), Positives = 66/160 (41%), Gaps = 11/160 (6%)
Query: 90 KMLKENPEEKLFIVHKAITDLSLQ-ETSADEMTFREGHQWEKIPLSGSNQEIRRQKERIT 148
K P +K KA+T + T + G + IP G+ +KE
Sbjct: 87 KKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAAIPAKGAKNGKNAKKEDSD 146
Query: 149 EQPL--KEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDN 206
E+ EE++ED +++ EIE + + A + DE+ + +++ DD++DD+
Sbjct: 147 EEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDS 206
Query: 207 CN--------NDEDEVRVIEFKKKHEEVSQFKEEGDASED 238
+ +V+ K K+ + +EE D ED
Sbjct: 207 EEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDED 246
Score = 41.2 bits (95), Expect = 0.001
Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 10/83 (12%)
Query: 149 EQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCN 208
E +EE E KG +AA++ P +A + DEE+ DE+ DDD+DD +
Sbjct: 203 EDDSEEEAMETTPAKGKKAAKVV------PVKAKNVAEDEDEEEDDEDEDDDDDEDDEDD 256
Query: 209 NDEDEVRVIEFKKKHEEVSQFKE 231
+DED+ E +++ EE KE
Sbjct: 257 DDEDD----EEEEEEEEEEPVKE 275
Score = 33.5 bits (75), Expect = 0.23
Identities = 18/88 (20%), Positives = 48/88 (54%), Gaps = 6/88 (6%)
Query: 153 KEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDED 212
++++D++ + +A E +K ++ + +K+ E + +E+ +D+DDD+ +DED
Sbjct: 196 EDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDED 255
Query: 213 EVRVIEFKKKHEEVSQFKEEGDASEDSP 240
+ + +E + +EE + +++P
Sbjct: 256 D------DDEDDEEEEEEEEEEPVKEAP 277
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 40.8 bits (94), Expect = 0.001
Identities = 34/143 (23%), Positives = 57/143 (39%), Gaps = 30/143 (20%)
Query: 155 EEDEDRKNKGHQAAEIEWLGFRKPSQAD-------------MLHSKHDEEQKVWDEEIDD 201
EEDED + +A E G + P + + L S+ +E + E D+
Sbjct: 919 EEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDE 978
Query: 202 DDDDNCNNDEDEVRVIEFKKKHEEVSQFKE-----------------EGDASEDSPLSSA 244
+DD+ DED ++ KK EVS ++ E D++ DS SS+
Sbjct: 979 EDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSS 1038
Query: 245 SSQAVTPDEQPTLGKKSDISRNA 267
SS + + + S S ++
Sbjct: 1039 SSSSSSSSSSSSSSSSSSSSESS 1061
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 40.8 bits (94), Expect = 0.001
Identities = 33/109 (30%), Positives = 52/109 (47%), Gaps = 20/109 (18%)
Query: 140 IRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEI 199
+RR+ R E EEDE K S ++ S +EE+ +EE
Sbjct: 1019 VRRRPARPLELDSGGEEDE------------------KESLSEEQESTEEEEEAEEEEEE 1060
Query: 200 DDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQA 248
+DDDDD+ ++D DE + E S+ K+EGD+ E+ +S +S+A
Sbjct: 1061 EDDDDDD-SDDRDESENDDEDTALSEASE-KDEGDSDEEETVSIVTSKA 1107
Score = 32.0 bits (71), Expect = 0.67
Identities = 35/176 (19%), Positives = 69/176 (39%), Gaps = 45/176 (25%)
Query: 125 GHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADML 184
G + EK LS + ++E E+ ++++D+D ++ + E + S+ D
Sbjct: 1033 GEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKD-- 1090
Query: 185 HSKHDEEQKVW------------------DEEIDDDDDDNCNNDEDEVRVIEFKKKHEEV 226
DEE+ V + E + + + DE+EV E +++ EE
Sbjct: 1091 EGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEE 1150
Query: 227 SQFKEEGDAS----------EDSPLSSAS---------------SQAVTPDEQPTL 257
EE AS E++ L+ + ++AV P+E+P++
Sbjct: 1151 EMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSM 1206
>gi|9257192 adducin 2 isoform a [Homo sapiens]
Length = 726
Score = 40.4 bits (93), Expect = 0.002
Identities = 40/149 (26%), Positives = 65/149 (43%), Gaps = 19/149 (12%)
Query: 114 ETSADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQA---AEI 170
E S+ M R + + +PL QE+ + +I EQ +D K+ G Q+ A +
Sbjct: 469 EKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQ-----NRQDVKSAGPQSQLLASV 523
Query: 171 EWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFK 230
R PS L SK DE+ K DD ++ N ++ E ++ +EV + K
Sbjct: 524 IAEKSRSPSTESQLMSKGDEDTK-------DDSEETVPNPFSQLTDQELEEYKKEVERKK 576
Query: 231 EEGDASEDS----PLSSASSQAVTPDEQP 255
E D +++ P S A S +P + P
Sbjct: 577 LELDGEKETAPEEPGSPAKSAPASPVQSP 605
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 40.4 bits (93), Expect = 0.002
Identities = 29/121 (23%), Positives = 59/121 (48%), Gaps = 17/121 (14%)
Query: 154 EEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDE 213
E+ DE +++G + +E +P D + D E++ EE D+DDD++ + EDE
Sbjct: 97 EDMDEKEEDEGEEYSEDN----DEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDE 152
Query: 214 VRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSDISRNAYSRYNT 273
++ EE + +EE + +ED ++ +++ + E K D + + Y Y+
Sbjct: 153 -------EEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTE------KDDNNNDEYDNYDE 199
Query: 274 I 274
+
Sbjct: 200 L 200
Score = 28.5 bits (62), Expect = 7.4
Identities = 25/116 (21%), Positives = 54/116 (46%), Gaps = 20/116 (17%)
Query: 149 EQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCN 208
E+ +EEE+E+ +N+ HQ + H+ E+ D+++D+ N
Sbjct: 155 EEEEEEEEEEEEENEDHQM------------------NCHNTRIMQDTEKDDNNNDEYDN 196
Query: 209 NDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSDIS 264
DE + + K E + ++ ++ +S ++++S D+ LG+KS++S
Sbjct: 197 YDELVAKSLLNLGKIAEDAAYRARTESEMNS--NTSNSLEDDSDKNENLGRKSELS 250
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.126 0.352
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,399,154
Number of Sequences: 37866
Number of extensions: 622361
Number of successful extensions: 6020
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 137
Number of HSP's successfully gapped in prelim test: 353
Number of HSP's that attempted gapping in prelim test: 3626
Number of HSP's gapped (non-prelim): 1461
length of query: 297
length of database: 18,247,518
effective HSP length: 102
effective length of query: 195
effective length of database: 14,385,186
effective search space: 2805111270
effective search space used: 2805111270
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.