Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 58331177

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|58331177 ermin, ERM-like protein isoform a [Homo sapiens]
         (297 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|58331177 ermin, ERM-like protein isoform a [Homo sapiens]          602   e-172
gi|58331175 ermin, ERM-like protein isoform b [Homo sapiens]          576   e-164
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]            50   2e-06
gi|21396500 HIRA interacting protein 3 [Homo sapiens]                  50   2e-06
gi|4505257 moesin [Homo sapiens]                                       46   3e-05
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    46   5e-05
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    45   6e-05
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    45   1e-04
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi...    45   1e-04
gi|217330641 IWS1 homolog [Homo sapiens]                               44   1e-04
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H...    44   2e-04
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap...    44   2e-04
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap...    44   2e-04
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]                44   2e-04
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]                 44   2e-04
gi|4506467 radixin [Homo sapiens]                                      44   2e-04
gi|4504487 histidine rich calcium binding protein precursor [Hom...    44   2e-04
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    43   3e-04
gi|115529449 upstream binding transcription factor, RNA polymera...    43   3e-04
gi|115529451 upstream binding transcription factor, RNA polymera...    43   3e-04
gi|7657671 upstream binding transcription factor, RNA polymerase...    43   3e-04
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    42   5e-04
gi|161702986 ezrin [Homo sapiens]                                      42   7e-04
gi|21614499 ezrin [Homo sapiens]                                       42   7e-04
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    42   7e-04
gi|55956788 nucleolin [Homo sapiens]                                   41   0.001
gi|55741677 SET domain containing 1A [Homo sapiens]                    41   0.001
gi|210032580 SET domain containing 1B [Homo sapiens]                   41   0.001
gi|9257192 adducin 2 isoform a [Homo sapiens]                          40   0.002
gi|60498973 myelin transcription factor 1-like [Homo sapiens]          40   0.002

>gi|58331177 ermin, ERM-like protein isoform a [Homo sapiens]
          Length = 297

 Score =  602 bits (1553), Expect = e-172
 Identities = 297/297 (100%), Positives = 297/297 (100%)

Query: 1   MKTLSPDRIQPHIMTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEP 60
           MKTLSPDRIQPHIMTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEP
Sbjct: 1   MKTLSPDRIQPHIMTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEP 60

Query: 61  SLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEM 120
           SLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEM
Sbjct: 61  SLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEM 120

Query: 121 TFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQ 180
           TFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQ
Sbjct: 121 TFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQ 180

Query: 181 ADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSP 240
           ADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSP
Sbjct: 181 ADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSP 240

Query: 241 LSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL 297
           LSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL
Sbjct: 241 LSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL 297


>gi|58331175 ermin, ERM-like protein isoform b [Homo sapiens]
          Length = 284

 Score =  576 bits (1484), Expect = e-164
 Identities = 284/284 (100%), Positives = 284/284 (100%)

Query: 14  MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEE 73
           MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEE
Sbjct: 1   MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEE 60

Query: 74  RRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPL 133
           RRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPL
Sbjct: 61  RRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPL 120

Query: 134 SGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQK 193
           SGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQK
Sbjct: 121 SGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQK 180

Query: 194 VWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDE 253
           VWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDE
Sbjct: 181 VWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDE 240

Query: 254 QPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL 297
           QPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL
Sbjct: 241 QPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL 284


>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 238

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 43/194 (22%), Positives = 89/194 (45%), Gaps = 16/194 (8%)

Query: 71  QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130
           +E  +K++    +    E+KM +E  E+      K        +   ++M  +E   WE+
Sbjct: 8   REREKKMREEEEMMREQEEKM-QEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 66

Query: 131 IPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSK--- 187
                  Q +  QKE++ EQ  +  E E+R  +     ++E +  +K +Q + +  +   
Sbjct: 67  EEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEK 126

Query: 188 -HDEEQKVWD-EEIDDDDDDNCNNDEDEVRVIEFK-KKHEEVSQFKEE---------GDA 235
             ++E+ +W+ EE   + ++     E+++R  E K ++ EE  Q +EE         G+A
Sbjct: 127 MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEA 186

Query: 236 SEDSPLSSASSQAV 249
            E SP  + ++Q +
Sbjct: 187 GEGSPQDNPTAQEI 200



 Score = 28.1 bits (61), Expect = 9.7
 Identities = 14/61 (22%), Positives = 33/61 (54%), Gaps = 2/61 (3%)

Query: 138 QEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDE 197
           +E  R +ER  E+ ++EEE+  R+ +     + E +  ++    +      ++E+K+W++
Sbjct: 2   REEERMRER--EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59

Query: 198 E 198
           E
Sbjct: 60  E 60


>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
          Length = 556

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 63/304 (20%), Positives = 121/304 (39%), Gaps = 37/304 (12%)

Query: 5   SPDRIQPHIMTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEG 64
           SPD   P     V A  + A+   ++ P    + + + S+E    D P          E 
Sbjct: 108 SPDYFGPPAKNGVAAEVSPAK---EENPRRASKAVEESSDEERQRDLPAQRGEESSEEEE 164

Query: 65  ALTKGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFRE 124
              KG   ++  ++      +S+  K  +E  EE         ++    + +A ++   +
Sbjct: 165 KGYKGKTRKKPVVKKQAPGKASVSRKQAREESEE---------SEAEPVQRTAKKVEGNK 215

Query: 125 GHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQAD-M 183
           G +  K     S +EI  QK+   E+ ++EEE E+ + KG         G RK ++ +  
Sbjct: 216 GTKSLKESEQESEEEILAQKKEQREEEVEEEEKEEDEEKGDWKPRTRSNGRRKSAREERS 275

Query: 184 LHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIE--FKKKHEEVSQFK----------E 231
              K   ++ + D + +++  +  ++ +D  R  E   ++K E+ +Q K          +
Sbjct: 276 CKQKSQAKRLLGDSDSEEEQKEAASSGDDSGRDREPPVQRKSEDRTQLKGGKRLSGSSED 335

Query: 232 EGDASEDSPLSSASSQAVTPDEQPTLGKKSDISRNAY----------SRYNTISYRKIRK 281
           E D+ +  P +  S +        T G++SD+ R              R N  S +  RK
Sbjct: 336 EEDSGKGEPTAKGSRKMARLGS--TSGEESDLEREVSDSEAGGGPQGERKNRSSKKSSRK 393

Query: 282 GNTK 285
           G T+
Sbjct: 394 GRTR 397


>gi|4505257 moesin [Homo sapiens]
          Length = 577

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 63/272 (23%), Positives = 113/272 (41%), Gaps = 23/272 (8%)

Query: 27  NGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERR--KLQGNMLLN 84
           N  K  E  ++   KI  E  ++   L   ++E   + A  +  ++ RR  +L+      
Sbjct: 325 NEKKKREMAEKEKEKIEREKEELMERLK--QIEEQTKKAQQELEEQTRRALELEQERKRA 382

Query: 85  SSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSG--SNQEIRR 142
            S  +K+ KE  E +           +L + S D+   +E    E   L+   S  E+ R
Sbjct: 383 QSEAEKLAKERQEAEE-------AKEALLQASRDQKKTQEQLALEMAELTARISQLEMAR 435

Query: 143 QKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDD 202
           QK+       +++    +++     AE++      P  A+   ++ DE+ +   E   D 
Sbjct: 436 QKKESEAVEWQQKAQMVQEDLEKTRAELK-TAMSTPHVAEPAENEQDEQDENGAEASADL 494

Query: 203 DDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSD 262
             D    D  E       +K+E V +  +    +  S L++A  ++          +   
Sbjct: 495 RADAMAKDRSEEERTTEAEKNERVQKHLK----ALTSELANARDESKKTANDMIHAENMR 550

Query: 263 ISRNAYSRYNTISYRKIRKGNTKQRIDEFESM 294
           + R+ Y      + R+IR+GNTKQRIDEFESM
Sbjct: 551 LGRDKYK-----TLRQIRQGNTKQRIDEFESM 577


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 44/199 (22%), Positives = 87/199 (43%), Gaps = 16/199 (8%)

Query: 71  QEER-RKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLS-LQETSADEMTFREGHQW 128
           Q+ER R+ +  M     M ++  K   EE++    K + +         ++M  +E + W
Sbjct: 364 QDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMW 423

Query: 129 EKIPLSGSNQEIRRQKERITEQPLKEEEDE---DRKNKGHQAAEI------EWLGFRKPS 179
           E+       Q +  QKE++ EQ   +E++E   +++ K     E+       W   +   
Sbjct: 424 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 483

Query: 180 QADML----HSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDA 235
           Q D +        D+EQK+WD+E    + D    +++E R+ E KK  ++  + +EE   
Sbjct: 484 QEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEE-RMREQKKMWQQEEKMREEKKT 542

Query: 236 SEDSPLSSASSQAVTPDEQ 254
            E    +    + +  +E+
Sbjct: 543 QEQEKKTWDQEEKMREEER 561



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 43/215 (20%), Positives = 87/215 (40%), Gaps = 33/215 (15%)

Query: 73  ERRKLQGNMLLNSSMEDKMLKENP-----EEKLFIVHKAITDLSLQETSADE-MTFREGH 126
           E++KL+         E+KM ++       EEK++   + + +   Q    ++ M  +E  
Sbjct: 301 EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 360

Query: 127 QWEKIPLSGSNQEIRRQKERITEQPLKEEEDE---DRKNKGHQAAEI------------- 170
            WE+       +E  R++E++ EQ  K +E+E   +R+ K  +  E              
Sbjct: 361 MWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 420

Query: 171 --------EWLGFRKPSQADML---HSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEF 219
                   EW   R P Q + L       ++E+K+W++E    D +     E ++   E 
Sbjct: 421 NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEK 480

Query: 220 KKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQ 254
            ++ E+    +EE    ++  +     +    DE+
Sbjct: 481 MREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDER 515



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 26/151 (17%), Positives = 67/151 (44%), Gaps = 4/151 (2%)

Query: 113 QETSADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEW 172
           +E    E   +   Q EK+      +E R +K R  E+ ++E+E++ ++ +     + E 
Sbjct: 538 EEKKTQEQEKKTWDQEEKMREEERMRE-REKKMREEEEMMREQEEKMQEQEEKMREQEEK 596

Query: 173 LGFRKPSQADMLHSKHDEEQKVWDEEIDD---DDDDNCNNDEDEVRVIEFKKKHEEVSQF 229
           +  ++    +      ++E+K+W++E +D   + ++     E++++  E K   +E    
Sbjct: 597 MWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR 656

Query: 230 KEEGDASEDSPLSSASSQAVTPDEQPTLGKK 260
           ++E    E         + +   E+   G++
Sbjct: 657 EQEEKMREQEEKMQGQEEKMREQEEKMQGQE 687



 Score = 33.5 bits (75), Expect = 0.23
 Identities = 51/224 (22%), Positives = 95/224 (42%), Gaps = 36/224 (16%)

Query: 36  QQTITKISEELTDVDSPLPH-YRVEPSLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKE 94
           + TIT  +EEL   ++ L    R+  S +  +    +E +RKL+    L   ++   L+E
Sbjct: 177 RNTIT--NEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQE 234

Query: 95  N---PEEKLFIVHKAITD----LSLQETSADEMTFREGHQWEKIP-----LSGSNQEIRR 142
                EE+L    K I      +  QE    E   +   Q EK+      L    +E+R 
Sbjct: 235 EMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELRE 294

Query: 143 QKERITEQP-LKEEEDE---------DRKNKGHQAAEIEW-----LGFRKPSQADMLHSK 187
           Q++ + EQ  L+E+E++         +++ K  +  E  W     L  ++    +     
Sbjct: 295 QEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKM 354

Query: 188 HDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKE 231
            D+E+++W++      D+     E+ +R  E   + EE  Q +E
Sbjct: 355 RDQEERMWEQ------DERLREKEERMREQEKMWEQEEKMQEEE 392



 Score = 32.3 bits (72), Expect = 0.52
 Identities = 30/161 (18%), Positives = 69/161 (42%), Gaps = 22/161 (13%)

Query: 72  EERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKI 131
           E+  K+Q         E+KM ++  E+K+    + + +        ++M  +E   WE+ 
Sbjct: 599 EQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWE------QEEKMQEQEEKMWEQ- 651

Query: 132 PLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEE 191
                 +++R Q+E++ EQ  K +  E++  +  +  + +    R+  +         +E
Sbjct: 652 -----EEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEE-----KMRGQE 701

Query: 192 QKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEE 232
           +K+W +E     +     +E      E ++K E +   KE+
Sbjct: 702 EKMWGQE-----EKMWGQEEKMWGQEEMREKEERIRDQKEK 737



 Score = 30.8 bits (68), Expect = 1.5
 Identities = 29/165 (17%), Positives = 77/165 (46%), Gaps = 13/165 (7%)

Query: 71  QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130
           QE+ R+ +  M      E+KM   + E+K++   + + +   +    +E    +   W++
Sbjct: 478 QEKMREQEDQMW---EQEEKM--RDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQ 532

Query: 131 IPLSGSNQEIRRQKERITEQPLKEEEDE---DRKNKGHQAAEIEWLGFRKPSQADMLHSK 187
                  ++ + Q+++  +Q  K  E+E   +R+ K  +  E E +  ++    +     
Sbjct: 533 EEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMRE--EEEMMREQEEKMQEQEEKM 590

Query: 188 HDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEE 232
            ++E+K+W++E    + +    +++E     ++++ E+  Q +EE
Sbjct: 591 REQEEKMWEQEEKMQEQEEKMWEQEEKM---WEQEEEDKMQEQEE 632


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 59/296 (19%), Positives = 127/296 (42%), Gaps = 42/296 (14%)

Query: 36  QQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERRKLQGNM-------LLNSSME 88
           Q  + ++  +L      LP  +++   +  L K  Q    KLQ  +        LN   E
Sbjct: 229 QLNVKELKRKLERAKLLLPQQQLQAEADH-LGKELQSVSAKLQAQVEENELWNRLNQQQE 287

Query: 89  DKMLKENP-----EEKLFIVHKAITDLSLQETSADEMTF--------REGHQWEKIPLSG 135
           +KM ++       EEK+    + I +   +    +EM +        +E   WEK     
Sbjct: 288 EKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 347

Query: 136 SNQEIRRQKERITEQPLKEEEDE---DRKNKGHQAAEIEWLGFRK--------PSQADML 184
             +E   ++E+I EQ  K +E+E   +++ +  Q A++ W    K          Q +M+
Sbjct: 348 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM-WRQEEKIREQEEKIREQEEMM 406

Query: 185 HSKH----DEEQKVWDEEID-DDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDS 239
             +     ++E+K+W++E +  + ++     E+++R  E KK  E+  + +E+ +  ++ 
Sbjct: 407 QEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQE-KKIREQEEKIREQEEMMQEQ 465

Query: 240 PLSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMM 295
                  +    +++  + ++ +  R    +      +KIR+   +++I E E MM
Sbjct: 466 EEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIRE-QEKKIRE--QEEKIREQEEMM 518



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 33/179 (18%)

Query: 69  GSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITD----LSLQETSADEMTFRE 124
           G QEE+   Q   +     E+KM ++  EEK+    K I +    +  QE    E   + 
Sbjct: 414 GEQEEKMWEQEEEM--QEQEEKMRRQ--EEKIREQEKKIREQEEKIREQEEMMQEQEEKM 469

Query: 125 GHQWEKI-----PLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPS 179
           G Q  K+      +    +++RRQ+E+I EQ  K  E E++  +                
Sbjct: 470 GEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIRE---------------- 513

Query: 180 QADMLHSKHDEEQKVWD-EEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASE 237
           Q +M+    ++E+K+W+ EE   + ++     E+++R  E K + +EV   ++E    E
Sbjct: 514 QEEMMQ---EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 36/165 (21%), Positives = 75/165 (45%), Gaps = 6/165 (3%)

Query: 71  QEERRKLQGNMLLNSSMEDKMLKE-NPEEKLFIVHKAITDLSLQETSADEMTFREGHQWE 129
           QEE+R+ +  +      +++  K    EEK+    + I +   QE    E   + G Q E
Sbjct: 362 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE---QEEMMQEQEEKMGEQEE 418

Query: 130 KIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHD 189
           K+       + + +K R  E+ ++E+E + R+ +     + E +  ++    +      +
Sbjct: 419 KMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCE 478

Query: 190 EEQKVWD-EEIDDDDDDNCNNDEDEVRVIEFK-KKHEEVSQFKEE 232
           +E K+ + EE     ++     E ++R  E K ++ EE+ Q +EE
Sbjct: 479 QEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 523


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 39/175 (22%), Positives = 80/175 (45%), Gaps = 11/175 (6%)

Query: 71  QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSA----DEMTFREGH 126
           QEE+ + Q   +     E KM ++  EEK+    K   +   QE       +E    +  
Sbjct: 435 QEEKIREQEEKI--REQEKKMWRQ--EEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEE 490

Query: 127 QW-EKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLH 185
            W +K  +    ++IR+Q+E++  Q  K  E E++  +  +    +    R+  +     
Sbjct: 491 IWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREE 550

Query: 186 SKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFK--KKHEEVSQFKEEGDASED 238
            K  E++K+W+EE   + +D     E+++R  E K  ++ E++ + +E+    E+
Sbjct: 551 EKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEE 605



 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 40/187 (21%), Positives = 83/187 (44%), Gaps = 19/187 (10%)

Query: 71  QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130
           +EE+R+ Q         EDKM ++  EEK   + +    +  QE    E   +   Q EK
Sbjct: 561 EEEKRQEQ---------EDKMWRQ--EEK---IREQEEKVWRQEEKIREQEEKRQEQEEK 606

Query: 131 IPLSGSNQEIRRQKERITEQP--LKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKH 188
             +    ++IR Q+E+I EQ   ++E+E++ R+ +     + E +G ++    +      
Sbjct: 607 --MWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQ 664

Query: 189 DEEQKVW-DEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQ 247
           ++E+ +W  EE   + +      E+++R  E   + +E   +++E    E         +
Sbjct: 665 EQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 724

Query: 248 AVTPDEQ 254
            +   E+
Sbjct: 725 KMRRQEE 731



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 41/211 (19%), Positives = 102/211 (48%), Gaps = 17/211 (8%)

Query: 88  EDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKERI 147
           E+K+ K+  EEK++   + I +   +    +E  +R+  +  +       +E   ++E+I
Sbjct: 502 EEKIRKQ--EEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKI 559

Query: 148 TEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQA-DMLHSKHDEEQKVW-DEEIDDDDDD 205
            E+  ++E+++    +  +  E E   +R+  +  +    + ++E+K+W  EE   + ++
Sbjct: 560 WEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEE 619

Query: 206 NCNNDEDEVRVIEFK-KKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSDIS 264
                E+++R  E K ++ EE++Q +EE    ++  +     +    +++ T+ ++ +  
Sbjct: 620 KIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKM--CEQEEKMQEQEETMWRQEEKI 677

Query: 265 RNAYSRYNTISYRKIRKGNTKQRIDEFESMM 295
           R           +KIR+   +++I E E MM
Sbjct: 678 RE--------QEKKIRE--QEEKIREQEEMM 698



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 37/198 (18%), Positives = 95/198 (47%), Gaps = 17/198 (8%)

Query: 71  QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130
           +EE+R+ Q  M      E+K+   + +E+++   + + +   +    +E  +R   Q EK
Sbjct: 468 EEEKRQEQEEMW---RQEEKI---HEQEEIWRQKEKMHEQEEKIRKQEEKVWR---QEEK 518

Query: 131 IPLSGSNQEIRRQKERI--TEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKH 188
           I      ++IR Q+E++   E+ ++E+E+  R+ +     E  W   ++  Q D +  + 
Sbjct: 519 I--REQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE 576

Query: 189 D----EEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSA 244
           +    +E+KVW +E    + +    +++E    + +K  E+  + +E+ +   +      
Sbjct: 577 EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIR 636

Query: 245 SSQAVTPDEQPTLGKKSD 262
             + +T +++  +G++ +
Sbjct: 637 EQEEMTQEQEEKMGEQEE 654



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 51/272 (18%), Positives = 112/272 (41%), Gaps = 31/272 (11%)

Query: 36  QQTITKISEELTDVDSPL-PHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKE 94
           Q  + ++  E  D+ S L   ++    LE AL+  + ++++             +++ KE
Sbjct: 150 QHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKA--------DRYIEELTKE 201

Query: 95  NPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKER----ITEQ 150
                L +    ITD  L+E +A      +  + EK  +  + +E++R+ ER    + +Q
Sbjct: 202 RDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQ 261

Query: 151 PLKEEEDEDRKNKGHQAAEIEW------LGFRKPSQADMLHSKHDEEQKVWDEEIDDDDD 204
            L+ E D   K     +A+++       L  R   Q +    + +E+ + W+E+I  + +
Sbjct: 262 QLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQ-EQE 320

Query: 205 DNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSDIS 264
           +     E+++R  E K + +E   +++E        +     + +   E+    K+  + 
Sbjct: 321 EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 380

Query: 265 RNAYSRYNTISYRKIRKGNTKQRIDEFESMMH 296
           R     +             +++I E E  MH
Sbjct: 381 RQEEMMW-----------EKEEKIRELEEKMH 401



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 37/190 (19%), Positives = 82/190 (43%), Gaps = 24/190 (12%)

Query: 71  QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130
           +EE+ + Q  M+     + + L+E   E+     + I +   +    +++  +E  Q ++
Sbjct: 375 KEEKMRRQEEMMWEKEEKIRELEEKMHEQ-----EKIREQEEKRQEEEKIREQEKRQEQE 429

Query: 131 IPLSGSNQEIRRQKERITEQPLK--------EEEDEDRKNKGHQAAEIEWLGFRKPS--- 179
             +    ++IR Q+E+I EQ  K         E+++ R+ +  Q  E  W    K     
Sbjct: 430 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQE 489

Query: 180 ----QADMLHSKHD----EEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKE 231
               Q + +H + +    +E+KVW +E    + +    +++E    + +K  E+   ++E
Sbjct: 490 EIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWRE 549

Query: 232 EGDASEDSPL 241
           E    E   +
Sbjct: 550 EEKMHEQEKI 559



 Score = 38.1 bits (87), Expect = 0.009
 Identities = 38/173 (21%), Positives = 75/173 (43%), Gaps = 25/173 (14%)

Query: 71  QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130
           QEE+R+ Q   +     + +  +E  +E+   + +    +  QE    E   + G Q EK
Sbjct: 596 QEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655

Query: 131 I-----PLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLH 185
           +      +    + + RQ+E+I EQ  K  E E++  +                Q +M+ 
Sbjct: 656 MCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIRE----------------QEEMMQ 699

Query: 186 SKHDEEQKVWD-EEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASE 237
              ++E+K+W+ EE   + ++     E+++R  E K   +EV   ++E    E
Sbjct: 700 ---EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749


>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 436

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 37/193 (19%), Positives = 88/193 (45%), Gaps = 13/193 (6%)

Query: 69  GSQEERRKLQGNMLLNSSMEDKMLKENP-----EEKLFIVHKAITDLSLQETSADEMTFR 123
           G QEE+ + Q   +     E+++ K+       EE++    + + +   Q    +E   +
Sbjct: 223 GEQEEQMRKQEEQM--GEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLK 280

Query: 124 EGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADM 183
           +  Q E+   +G  +E  R++E    + ++E+E++ R+ +     + E +G ++    + 
Sbjct: 281 QKEQTEQEEQTGEQEEQMREQE----EQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQ 336

Query: 184 LHSKHDEEQKVW-DEEIDDDDDDNCNNDEDEVRVIEFK-KKHEEVSQFKEEGDASEDSPL 241
                ++++++W  EE   + ++     E++VR  E + +K EE  + +EE    ++  +
Sbjct: 337 KEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQM 396

Query: 242 SSASSQAVTPDEQ 254
                Q     EQ
Sbjct: 397 GEQKEQMGEQKEQ 409



 Score = 32.0 bits (71), Expect = 0.67
 Identities = 23/143 (16%), Positives = 62/143 (43%), Gaps = 1/143 (0%)

Query: 113 QETSADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEW 172
           QE    E   + G Q E++         + ++ R  E+ + E+E++ +K +     + E 
Sbjct: 197 QEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQ 256

Query: 173 LGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFK-KKHEEVSQFKE 231
           +  ++    +      ++E+++  ++   + ++     E+++R  E + ++ EE  + +E
Sbjct: 257 MRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQE 316

Query: 232 EGDASEDSPLSSASSQAVTPDEQ 254
           E    ++  +     Q     EQ
Sbjct: 317 EQMREQEEQMGKQEEQMWEQKEQ 339


>gi|217330641 IWS1 homolog [Homo sapiens]
          Length = 819

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 60/286 (20%), Positives = 114/286 (39%), Gaps = 34/286 (11%)

Query: 7   DRIQPHIM---TDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLE 63
           D ++P I    ++ P     ++   ++PP+   +     SEEL     P P      S E
Sbjct: 176 DALKPQISDSESEEPPRHQASDSENEEPPK--PRMSDSESEEL-----PKPQVSDSESEE 228

Query: 64  GALTKGSQEERRKLQGNMLLNSSMEDKMLKE-NPEEKLFIVHKAITDLSLQETSADEMTF 122
               + S  E  +L    + +S  ED    + +  E   +    I+D   ++   ++ + 
Sbjct: 229 PPRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASD 288

Query: 123 REGHQWEKIPLSGSNQEIRRQ---KERITE------QPLKEEEDEDRKNKGHQAAEIEWL 173
            E  +  K  +S S  E  ++    +  TE      Q  + ++D DR+NKG    E++  
Sbjct: 289 SENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDT-EMQND 347

Query: 174 GFRKPSQADM--LHSKHDEEQKVWDEEIDDDDDDNCNNDED----EVRVIEFKKKHEEVS 227
            F   S  D    HS   EE++   +++D D+D+    +E     +  V+   +  E+ S
Sbjct: 348 SFHSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKAS 407

Query: 228 QFK-------EEGDASEDSPLSSASSQAVTPDEQPTLGKKSDISRN 266
             K       ++ D+   S  S    + +  D +   GK+    +N
Sbjct: 408 AKKSRVVSDADDSDSDAVSDKSGKREKTIASDSEEEAGKELSDKKN 453


>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
           sapiens]
          Length = 1251

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 39/178 (21%), Positives = 79/178 (44%), Gaps = 5/178 (2%)

Query: 80  NMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQE 139
           ++L    +E  ++ E  E      H+ ++  S Q T        E    EK+P   S  E
Sbjct: 293 SILPGGQVEPDLVLEEVEPPWEDAHQDVST-SPQGTEVVPAYEEENKAVEKMPRELSRIE 351

Query: 140 IRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDE-- 197
             ++ E   E+  +EEE+E+       +  +  +G  + S+ D    +   +QK+W+E  
Sbjct: 352 EEKEDEEEEEEEEEEEEEEEVTEVLLDSCVVSQVGVGQ-SEEDGTRPQSTSDQKLWEEVG 410

Query: 198 -EIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQ 254
            E   + ++    + +EV   E +K+ ++ ++ KEE +A  ++  S   +    P+ Q
Sbjct: 411 EEAKKEAEEKAKEEAEEVAEEEAEKEPQDWAETKEEPEAEAEAASSGVPATKQHPEVQ 468


>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
           sapiens]
          Length = 805

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 57/294 (19%), Positives = 118/294 (40%), Gaps = 38/294 (12%)

Query: 16  DVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERR 75
           D P    +++ + D+  E+ +      S ++T   SP+P    E   +  +T+  +E + 
Sbjct: 278 DGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSPVPQ---EEHSDPEMTEEEKEYQM 334

Query: 76  KLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSG 135
            L   MLL      ++L +  +E+++ V K   D   + T A      +      +   G
Sbjct: 335 MLLTKMLLT-----EILLDVTDEEIYYVAK---DAHRKATKAPAKQLAQSSALASLTGLG 386

Query: 136 ------SNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHD 189
                 S      + +R +E    + +DE+ +++  Q  E  W   RK  +  +LH K  
Sbjct: 387 GLGGYGSGDSEDERSDRGSES--SDTDDEELRHRIRQKQEAFW---RKEKEQQLLHDKQM 441

Query: 190 EEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPL-------- 241
           EE+K   E +  + ++  + +++ + ++E ++   +V   K+       S L        
Sbjct: 442 EEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKE 501

Query: 242 --------SSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQR 287
                   S +SS   +     T    S +S ++YS  +  S    R  + K++
Sbjct: 502 KEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRK 555


>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
           sapiens]
          Length = 805

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 57/294 (19%), Positives = 118/294 (40%), Gaps = 38/294 (12%)

Query: 16  DVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERR 75
           D P    +++ + D+  E+ +      S ++T   SP+P    E   +  +T+  +E + 
Sbjct: 278 DGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSPVPQ---EEHSDPEMTEEEKEYQM 334

Query: 76  KLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSG 135
            L   MLL      ++L +  +E+++ V K   D   + T A      +      +   G
Sbjct: 335 MLLTKMLLT-----EILLDVTDEEIYYVAK---DAHRKATKAPAKQLAQSSALASLTGLG 386

Query: 136 ------SNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHD 189
                 S      + +R +E    + +DE+ +++  Q  E  W   RK  +  +LH K  
Sbjct: 387 GLGGYGSGDSEDERSDRGSES--SDTDDEELRHRIRQKQEAFW---RKEKEQQLLHDKQM 441

Query: 190 EEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPL-------- 241
           EE+K   E +  + ++  + +++ + ++E ++   +V   K+       S L        
Sbjct: 442 EEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKE 501

Query: 242 --------SSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQR 287
                   S +SS   +     T    S +S ++YS  +  S    R  + K++
Sbjct: 502 KEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRK 555


>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
          Length = 755

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 37/193 (19%), Positives = 85/193 (44%), Gaps = 34/193 (17%)

Query: 85  SSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEI---- 140
           + +E  + +E  E++L   H+ + D  L+E  ++   F +    + +   GS +E     
Sbjct: 568 NGLEKDLDEEGSEKEL---HENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDS 624

Query: 141 -RRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEI 199
             +++E  T + + ++E ++++++       E+   +    AD    + D ++K+++E  
Sbjct: 625 DEKEEEEDTYEKVFDDESDEKEDE-------EYADEKGLEAADKKAEEGDADEKLFEESD 677

Query: 200 DDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDAS-------------------EDSP 240
           D +D+D    + ++     F+        F EE D+S                   E+ P
Sbjct: 678 DKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLGGFGSVEEGP 737

Query: 241 LSSASSQAVTPDE 253
           LS+ SS  ++ D+
Sbjct: 738 LSTGSSFILSSDD 750



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 48/206 (23%), Positives = 96/206 (46%), Gaps = 17/206 (8%)

Query: 61  SLEGALTKGSQEERRKLQGNM--LLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSAD 118
           S EG   +GS+E+  K +     L N   E+ + KE+ ++   +  ++  ++   + S +
Sbjct: 485 SEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDD---LNKESEEEVGPTKESEE 541

Query: 119 EMTFREGHQ--WEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFR 176
           + + +E  +   EK    GS +E    +E   E+ L EE  E   ++     E+E     
Sbjct: 542 DDSEKESDEDCSEKQSEDGSEREF---EENGLEKDLDEEGSEKELHENVLDKELE----- 593

Query: 177 KPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDAS 236
             + ++    + D  +KV DEE  + + D  ++DE E     ++K  ++ S  KE+ + +
Sbjct: 594 -ENDSENSEFEDDGSEKVLDEEGSEREFDE-DSDEKEEEEDTYEKVFDDESDEKEDEEYA 651

Query: 237 EDSPLSSASSQAVTPDEQPTLGKKSD 262
           ++  L +A  +A   D    L ++SD
Sbjct: 652 DEKGLEAADKKAEEGDADEKLFEESD 677


>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
          Length = 755

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 37/193 (19%), Positives = 85/193 (44%), Gaps = 34/193 (17%)

Query: 85  SSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEI---- 140
           + +E  + +E  E++L   H+ + D  L+E  ++   F +    + +   GS +E     
Sbjct: 568 NGLEKDLDEEGSEKEL---HENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDS 624

Query: 141 -RRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEI 199
             +++E  T + + ++E ++++++       E+   +    AD    + D ++K+++E  
Sbjct: 625 DEKEEEEDTYEKVFDDESDEKEDE-------EYADEKGLEAADKKAEEGDADEKLFEESD 677

Query: 200 DDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDAS-------------------EDSP 240
           D +D+D    + ++     F+        F EE D+S                   E+ P
Sbjct: 678 DKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLGGFGSVEEGP 737

Query: 241 LSSASSQAVTPDE 253
           LS+ SS  ++ D+
Sbjct: 738 LSTGSSFILSSDD 750



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 48/206 (23%), Positives = 96/206 (46%), Gaps = 17/206 (8%)

Query: 61  SLEGALTKGSQEERRKLQGNM--LLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSAD 118
           S EG   +GS+E+  K +     L N   E+ + KE+ ++   +  ++  ++   + S +
Sbjct: 485 SEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDD---LNKESEEEVGPTKESEE 541

Query: 119 EMTFREGHQ--WEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFR 176
           + + +E  +   EK    GS +E    +E   E+ L EE  E   ++     E+E     
Sbjct: 542 DDSEKESDEDCSEKQSEDGSEREF---EENGLEKDLDEEGSEKELHENVLDKELE----- 593

Query: 177 KPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDAS 236
             + ++    + D  +KV DEE  + + D  ++DE E     ++K  ++ S  KE+ + +
Sbjct: 594 -ENDSENSEFEDDGSEKVLDEEGSEREFDE-DSDEKEEEEDTYEKVFDDESDEKEDEEYA 651

Query: 237 EDSPLSSASSQAVTPDEQPTLGKKSD 262
           ++  L +A  +A   D    L ++SD
Sbjct: 652 DEKGLEAADKKAEEGDADEKLFEESD 677


>gi|4506467 radixin [Homo sapiens]
          Length = 583

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 12/110 (10%)

Query: 185 HSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSA 244
           H +HDE       E+ ++   N  ++E+  RV E +K      Q +     +  S L+ A
Sbjct: 486 HDEHDENNAEASAELSNEGVMNHRSEEE--RVTETQKNERVKKQLQ-----ALSSELAQA 538

Query: 245 SSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESM 294
             +           +     R+ Y      + R+IR+GNTKQRIDEFE+M
Sbjct: 539 RDETKKTQNDVLHAENVKAGRDKYK-----TLRQIRQGNTKQRIDEFEAM 583


>gi|4504487 histidine rich calcium binding protein precursor [Homo
           sapiens]
          Length = 699

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 35/130 (26%), Positives = 52/130 (40%), Gaps = 4/130 (3%)

Query: 111 SLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEI 170
           S Q+   DE+   E H    I   G         E   E+  +EEE+E     GHQA   
Sbjct: 159 SHQDEDEDEVVSSEHHH--HILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRH 216

Query: 171 EWLGFRKPSQADMLHSKH--DEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQ 228
              G  +       H  H      +  +E+ DDDDDD+ ++D+D+V +    + H     
Sbjct: 217 RGHGSEEDEDVSDGHHHHGPSHRHQGHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGH 276

Query: 229 FKEEGDASED 238
             EE +   D
Sbjct: 277 GIEEDEDVSD 286



 Score = 32.3 bits (72), Expect = 0.52
 Identities = 24/104 (23%), Positives = 44/104 (42%), Gaps = 19/104 (18%)

Query: 137 NQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWD 196
           + E   Q E+ T    +++EDE+ + +GH                    S + EE++  D
Sbjct: 498 DDESSEQGEKGTHHGSRDQEDEEDEEEGHGL------------------SLNQEEEEEED 539

Query: 197 EEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSP 240
           +E +++++D    +E           H E  + +EEG   ED P
Sbjct: 540 KEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEEEG-LEEDEP 582



 Score = 29.6 bits (65), Expect = 3.3
 Identities = 28/146 (19%), Positives = 59/146 (40%), Gaps = 13/146 (8%)

Query: 117 ADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQ-----PLKEEEDEDRKNKGHQAAEIE 171
           +DE  F++ ++ E +P    ++  R + E ++ +     P   +  +D +    Q   I+
Sbjct: 401 SDEEDFQDEYKTE-VPHHHHHRVPREEDEEVSAELGHQAPSHRQSHQDEETGHGQRGSIK 459

Query: 172 WLGFRKPSQA---DMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQ 228
            +    P      D  H + D+ +    EE + ++D   + ++DE      K  H     
Sbjct: 460 EMSHHPPGHTVVKDRSHLRKDDSE----EEKEKEEDPGSHEEDDESSEQGEKGTHHGSRD 515

Query: 229 FKEEGDASEDSPLSSASSQAVTPDEQ 254
            ++E D  E   LS    +    D++
Sbjct: 516 QEDEEDEEEGHGLSLNQEEEEEEDKE 541


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 45/172 (26%), Positives = 82/172 (47%), Gaps = 17/172 (9%)

Query: 71  QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITD----LSLQETSADEMTFREGH 126
           QEE+   Q   +     E+KM ++  EEK+    + I +    +  QE    E   + G 
Sbjct: 500 QEEKMHDQEEKI--REQEEKMWRQ--EEKIREQEEKIREQEEKIREQEEMMQEQEEKMGE 555

Query: 127 QWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHS 186
           Q EK+      +++RRQ+E+I EQ   EE+  ++K K  +  E  W    K  + + +  
Sbjct: 556 QEEKMQ---EQEKMRRQEEKIREQ---EEKIREQKEKIREQEEKIWEQEEKIREQEEM-- 607

Query: 187 KHDEEQKVWD-EEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASE 237
             ++E+K+W+ EE   + ++     E+++R  E K   +EV   ++E    E
Sbjct: 608 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 659



 Score = 38.1 bits (87), Expect = 0.009
 Identities = 43/208 (20%), Positives = 94/208 (45%), Gaps = 20/208 (9%)

Query: 36  QQTITKISEELTDVDSPL-PHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKE 94
           Q  + ++  E  D+ S L   ++    LE AL+  + ++++             +++ KE
Sbjct: 150 QHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKA--------DRYIEELTKE 201

Query: 95  NPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKER----ITEQ 150
                L +    ITD  L+E +A      +  + EK  +  + +E++R+ ER    + +Q
Sbjct: 202 RDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQ 261

Query: 151 PLKEEEDEDRKNKGHQAAEIEW------LGFRKPSQADMLHSKHDEEQKVWDEEIDDDDD 204
            L+ E D   K     +A+++       L  R   Q +    + +E+ + W+E+I  + +
Sbjct: 262 QLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQ-EQE 320

Query: 205 DNCNNDEDEVRVIEFKKKHEEVSQFKEE 232
           +     E+++R  E K + +E   +++E
Sbjct: 321 EKIREQEEKIREQEEKMRRQEEMMWEKE 348



 Score = 35.0 bits (79), Expect = 0.079
 Identities = 31/161 (19%), Positives = 69/161 (42%), Gaps = 17/161 (10%)

Query: 71  QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130
           QEE+ + Q  M+     E+KM ++  EE ++                ++M   E   WEK
Sbjct: 333 QEEKMRRQEEMMWEK--EEKMRRQ--EEMMW-------------EKEEKMRRLEEMMWEK 375

Query: 131 IPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDE 190
                  +E   ++E+I EQ  K +E+E  + +  +  +   +  ++    +      ++
Sbjct: 376 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 435

Query: 191 EQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKE 231
           E+K+W +E    + +    +E      E  ++ E++ + +E
Sbjct: 436 EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE 476



 Score = 34.7 bits (78), Expect = 0.10
 Identities = 32/153 (20%), Positives = 71/153 (46%), Gaps = 15/153 (9%)

Query: 88  EDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKERI 147
           ++K+ K+  EEK++   + + D   QE    E   +   Q EKI      ++IR Q+E+I
Sbjct: 487 QEKIRKQ--EEKVWRQEEKMHD---QEEKIREQEEKMWRQEEKI--REQEEKIREQEEKI 539

Query: 148 TEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSK--------HDEEQKVWDEEI 199
            EQ    +E E++  +  +  + +    R+  +      K         ++E+K+W++E 
Sbjct: 540 REQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEE 599

Query: 200 DDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEE 232
              + +    +++E    + +K  E+  + +E+
Sbjct: 600 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 632



 Score = 32.0 bits (71), Expect = 0.67
 Identities = 39/170 (22%), Positives = 78/170 (45%), Gaps = 18/170 (10%)

Query: 71  QEERRKLQGNMLLNSSMEDKMLKENPE-----EKLFIVHKAITDLSLQETSADEMTFREG 125
           +EE+R+ Q  M      +++ ++E  E     EK+    K    +  QE        +  
Sbjct: 454 EEEKRQEQEEMW----RQEEKIREQEEIWRQKEKMHEQEK----IRKQEEKVWRQEEKMH 505

Query: 126 HQWEKIPLSGSNQEIRRQKERITEQP--LKEEEDEDRKNKGHQAAEIEWLGFRKPSQADM 183
            Q EKI      +++ RQ+E+I EQ   ++E+E++ R+ +     + E +G ++    + 
Sbjct: 506 DQEEKI--REQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ 563

Query: 184 LHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFK-KKHEEVSQFKEE 232
              +  EE+    EE   +  +     E+++   E K ++ EE+ Q +EE
Sbjct: 564 EKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEE 613



 Score = 28.9 bits (63), Expect = 5.7
 Identities = 29/118 (24%), Positives = 57/118 (48%), Gaps = 19/118 (16%)

Query: 69  GSQEERRKLQGNMLLNSS----MEDKMLKENP-----EEKLFIVHKAITDLSLQETSADE 119
           G QEE+ + Q  M          E+K+ ++       EEK++   + I +   QE    E
Sbjct: 554 GEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIRE---QEEMMQE 610

Query: 120 MTFREGHQWEKI-----PLSGSNQEIRRQKERITEQP--LKEEEDEDRKNKGHQAAEI 170
              +   Q EK+      +    +++RRQ+E++ EQ   L+++E++ ++++ H  A I
Sbjct: 611 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668


>gi|115529449 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 57/221 (25%), Positives = 92/221 (41%), Gaps = 38/221 (17%)

Query: 30  KPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMED 89
           KPP NG Q   K S+EL   +  L H    P  E  +  GS+ +R       +  S  E 
Sbjct: 532 KPPMNGYQ---KFSQELLS-NGELNHL---PLKERMVEIGSRWQR-------ISQSQKEH 577

Query: 90  KMLKENPEEKLFIVHKAITDLSLQETSADEMTFRE---GHQWEKIPLSGSNQEIRRQK-E 145
                  ++K + VH  +   SL  +  D   ++E     +     L G N +  R   +
Sbjct: 578 YKKLAEEQQKQYKVHLDLWVKSL--SPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQ 635

Query: 146 RITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDD 205
             +E    +EEDED +++  +  + E  G       D   S  ++E +  DE  +DD+D+
Sbjct: 636 SKSESEEDDEEDEDDEDEDEEEEDDE-NGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 694

Query: 206 NCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASS 246
           + + D+DE                 +E + SE S  SS+SS
Sbjct: 695 DDDEDDDE-----------------DEDNESEGSSSSSSSS 718


>gi|115529451 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 57/221 (25%), Positives = 92/221 (41%), Gaps = 38/221 (17%)

Query: 30  KPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMED 89
           KPP NG Q   K S+EL   +  L H    P  E  +  GS+ +R       +  S  E 
Sbjct: 532 KPPMNGYQ---KFSQELLS-NGELNHL---PLKERMVEIGSRWQR-------ISQSQKEH 577

Query: 90  KMLKENPEEKLFIVHKAITDLSLQETSADEMTFRE---GHQWEKIPLSGSNQEIRRQK-E 145
                  ++K + VH  +   SL  +  D   ++E     +     L G N +  R   +
Sbjct: 578 YKKLAEEQQKQYKVHLDLWVKSL--SPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQ 635

Query: 146 RITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDD 205
             +E    +EEDED +++  +  + E  G       D   S  ++E +  DE  +DD+D+
Sbjct: 636 SKSESEEDDEEDEDDEDEDEEEEDDE-NGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 694

Query: 206 NCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASS 246
           + + D+DE                 +E + SE S  SS+SS
Sbjct: 695 DDDEDDDE-----------------DEDNESEGSSSSSSSS 718


>gi|7657671 upstream binding transcription factor, RNA polymerase I
           isoform a [Homo sapiens]
          Length = 764

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 57/221 (25%), Positives = 92/221 (41%), Gaps = 38/221 (17%)

Query: 30  KPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMED 89
           KPP NG Q   K S+EL   +  L H    P  E  +  GS+ +R       +  S  E 
Sbjct: 569 KPPMNGYQ---KFSQELLS-NGELNHL---PLKERMVEIGSRWQR-------ISQSQKEH 614

Query: 90  KMLKENPEEKLFIVHKAITDLSLQETSADEMTFRE---GHQWEKIPLSGSNQEIRRQK-E 145
                  ++K + VH  +   SL  +  D   ++E     +     L G N +  R   +
Sbjct: 615 YKKLAEEQQKQYKVHLDLWVKSL--SPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQ 672

Query: 146 RITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDD 205
             +E    +EEDED +++  +  + E  G       D   S  ++E +  DE  +DD+D+
Sbjct: 673 SKSESEEDDEEDEDDEDEDEEEEDDE-NGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 731

Query: 206 NCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASS 246
           + + D+DE                 +E + SE S  SS+SS
Sbjct: 732 DDDEDDDE-----------------DEDNESEGSSSSSSSS 755


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 44/209 (21%), Positives = 80/209 (38%), Gaps = 32/209 (15%)

Query: 73  ERRKLQGNMLLNSSMEDKMLKEN---PEEKLFIVHKAITDLSLQETSADEMTFREGHQWE 129
           E +K+Q         E+KM +E      EK     K   +        ++M  +E + WE
Sbjct: 428 EEKKMQEQEKKTRDQEEKMQEEERIREREK-----KMREEEETMREQEEKMQKQEENMWE 482

Query: 130 KIPLSGSNQEIRRQKERITEQPLKEEEDE---DRKNKGHQAAEI------EWLGFRKPSQ 180
           +       Q +  QKE++ EQ   +E++E   +++ K     E+       W   +   Q
Sbjct: 483 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 542

Query: 181 ADML----HSKHDEEQKVWDEEIDDD-----------DDDNCNNDEDEVRVIEFKKKHEE 225
            D +        D+EQK+WD+E   +           D +    +E+ +R  E K + EE
Sbjct: 543 EDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE 602

Query: 226 VSQFKEEGDASEDSPLSSASSQAVTPDEQ 254
               ++E    E         + +   E+
Sbjct: 603 EMMREQEEKMQEQEEKMQEQEEKMWEQEE 631



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 42/186 (22%), Positives = 82/186 (44%), Gaps = 27/186 (14%)

Query: 71  QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130
           QEE+   Q   L     E KM ++  EEK++   K + +   +E    E   RE      
Sbjct: 291 QEEKMWRQEERL--REQEGKMREQ--EEKMWRQEKRLREQE-KELREQEKELRE------ 339

Query: 131 IPLSGSNQEIRRQKERITEQPLK--EEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKH 188
                  +E+R Q+E++ EQ  K  E+E++ R+ +     + E L  ++    +      
Sbjct: 340 ------QKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 393

Query: 189 DEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQA 248
           D+E+++W++      D+     E+ +R  E +K  E+V + +EE    E    +    + 
Sbjct: 394 DQEERMWEQ------DERLREKEERMR--EQEKMWEQVEKMREEKKMQEQEKKTRDQEEK 445

Query: 249 VTPDEQ 254
           +  +E+
Sbjct: 446 MQEEER 451



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 34/162 (20%), Positives = 66/162 (40%), Gaps = 12/162 (7%)

Query: 71  QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130
           +E  +K++    +    E+KM +E  E+      K        +   ++M  +E   WE+
Sbjct: 592 REREKKMREEEEMMREQEEKM-QEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 650

Query: 131 IPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDE 190
                  Q +  QKE++ E    +E++     K  +  E  W       Q  M     ++
Sbjct: 651 EEKMWEQQRLPEQKEKLWEHEKMQEQE-----KMQEQEEKIW------EQEKMEKKTQEQ 699

Query: 191 EQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEE 232
           E+K WD+E   +++     ++      E  ++ EE  Q +EE
Sbjct: 700 EKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEE 741



 Score = 34.7 bits (78), Expect = 0.10
 Identities = 36/190 (18%), Positives = 77/190 (40%), Gaps = 23/190 (12%)

Query: 66  LTKGSQEERRKL--QGNMLLNSSMEDKMLKENPEEKLFIVH--KAITDLSLQETSADEMT 121
           + K +QE+ +K   Q  M    SM ++  K   EE++      K        +   +EM 
Sbjct: 692 MEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMW 751

Query: 122 FREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEED---EDRKNKGHQAAEIEWLGFRKP 178
            +E   WE+       Q +  QKE++ E    +E++   E  +    Q  ++     +  
Sbjct: 752 EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMR 811

Query: 179 SQADMLHSKHD----EEQKVWDEE------------IDDDDDDNCNNDEDEVRVIEFKKK 222
            Q + +  + +    +E+K+W +E             ++  ++     E+++R  E K +
Sbjct: 812 GQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMR 871

Query: 223 HEEVSQFKEE 232
            +E    ++E
Sbjct: 872 GQEEKMREQE 881



 Score = 33.9 bits (76), Expect = 0.18
 Identities = 36/189 (19%), Positives = 78/189 (41%), Gaps = 31/189 (16%)

Query: 71  QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130
           QEE+   Q   L     ++K ++E  E+K+    + + +   +    +E    +   WE+
Sbjct: 367 QEEKMWRQEERLWE---QEKQMREQ-EQKMRDQEERMWEQDERLREKEERMREQEKMWEQ 422

Query: 131 IPLSGSNQEIRRQKERITEQPLKEEEDE---DRKNKGHQAAEI----------------- 170
           +      ++++ Q+++  +Q  K +E+E   +R+ K  +  E                  
Sbjct: 423 VEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE 482

Query: 171 ----EWLGFRKPSQADML---HSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKH 223
               EW   R P Q + L       ++E+K+W++E    D +     E ++   E  ++ 
Sbjct: 483 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 542

Query: 224 EEVSQFKEE 232
           E+    +EE
Sbjct: 543 EDQMWEQEE 551



 Score = 32.7 bits (73), Expect = 0.39
 Identities = 28/130 (21%), Positives = 58/130 (44%), Gaps = 11/130 (8%)

Query: 71  QEERRKLQGNMLLNSSMEDKMLKEN--PEEKLFIVHKAITDLSLQETSADEMTFREGHQW 128
           QE+  K+          E+KM ++   PE+K     K      +QE   ++M  +E   W
Sbjct: 634 QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQK----EKLWEHEKMQEQ--EKMQEQEEKIW 687

Query: 129 EKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKH 188
           E+  +    QE   Q+++  +Q    EE+  R+ +     E E +  ++    +      
Sbjct: 688 EQEKMEKKTQE---QEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQ 744

Query: 189 DEEQKVWDEE 198
           ++E+++W++E
Sbjct: 745 EQEEEMWEQE 754



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 27/134 (20%), Positives = 64/134 (47%), Gaps = 11/134 (8%)

Query: 71  QEERRKLQGNMLLNSSMEDKMLKENP----EEKLFIVHKAITDLSLQETSADEMTFREGH 126
           QEE+ + Q  M      E KM ++      E++++   + + D   +    +E   ++  
Sbjct: 516 QEEKIRDQEEMW---GQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQ 572

Query: 127 QWEKIPLSGSNQEIRRQKERITEQP--LKEEEDEDRKNKGHQAAEIEWLGFRKPSQADML 184
           + EK   +   +E  R++ER+ E+   ++EEE+  R+ +     + E +  ++    +  
Sbjct: 573 EQEK--KTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQE 630

Query: 185 HSKHDEEQKVWDEE 198
               ++E+K+W++E
Sbjct: 631 EKMQEQEEKMWEQE 644



 Score = 29.6 bits (65), Expect = 3.3
 Identities = 30/168 (17%), Positives = 77/168 (45%), Gaps = 4/168 (2%)

Query: 88  EDKMLKENPEEKLFIVHKAITDLSLQ-ETSADEMTFREGHQWEKIPLSGSNQEIRRQKER 146
           ED+M ++  EEK+    + + D   + E    E   +   Q EK+      +E R +K R
Sbjct: 543 EDQMWEQ--EEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRE-REKKMR 599

Query: 147 ITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDN 206
             E+ ++E+E++ ++ +     + E +  ++    +      ++E+K+W++E    +   
Sbjct: 600 EEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 659

Query: 207 CNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQ 254
               ++++   E  ++ E++ + +E+    E     +   +  T D++
Sbjct: 660 LPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQE 707


>gi|161702986 ezrin [Homo sapiens]
          Length = 586

 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 63/241 (26%), Positives = 103/241 (42%), Gaps = 48/241 (19%)

Query: 68  KGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQ 127
           K +QEE  +L+          D+M     +E+L    +A+  +  QE  A E+       
Sbjct: 380 KRAQEEAERLEA---------DRMAALRAKEEL--ERQAVDQIKSQEQLAAELA----EY 424

Query: 128 WEKIPLSGSNQEIRRQKERITEQ---PLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADML 184
             KI L    +E RR+KE   E+     KE +D+  K K     E+  +    P     +
Sbjct: 425 TAKIALL---EEARRRKEDEVEEWQHRAKEAQDDLVKTK----EELHLVMTAPPPPPPPV 477

Query: 185 HS--KHDEEQKVWDEEIDDD------DDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDAS 236
           +    +  ++ + DE  +          +   +D +E + I   +K+E V +        
Sbjct: 478 YEPVSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQR-------- 529

Query: 237 EDSPLSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISY---RKIRKGNTKQRIDEFES 293
           +   LSS  SQA   +++      +DI  N   R     Y   R+IR+GNTKQRIDEFE+
Sbjct: 530 QLLTLSSELSQARDENKRT----HNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEA 585

Query: 294 M 294
           +
Sbjct: 586 L 586


>gi|21614499 ezrin [Homo sapiens]
          Length = 586

 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 63/241 (26%), Positives = 103/241 (42%), Gaps = 48/241 (19%)

Query: 68  KGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQ 127
           K +QEE  +L+          D+M     +E+L    +A+  +  QE  A E+       
Sbjct: 380 KRAQEEAERLEA---------DRMAALRAKEEL--ERQAVDQIKSQEQLAAELA----EY 424

Query: 128 WEKIPLSGSNQEIRRQKERITEQ---PLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADML 184
             KI L    +E RR+KE   E+     KE +D+  K K     E+  +    P     +
Sbjct: 425 TAKIALL---EEARRRKEDEVEEWQHRAKEAQDDLVKTK----EELHLVMTAPPPPPPPV 477

Query: 185 HS--KHDEEQKVWDEEIDDD------DDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDAS 236
           +    +  ++ + DE  +          +   +D +E + I   +K+E V +        
Sbjct: 478 YEPVSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQR-------- 529

Query: 237 EDSPLSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISY---RKIRKGNTKQRIDEFES 293
           +   LSS  SQA   +++      +DI  N   R     Y   R+IR+GNTKQRIDEFE+
Sbjct: 530 QLLTLSSELSQARDENKRT----HNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEA 585

Query: 294 M 294
           +
Sbjct: 586 L 586


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 40/202 (19%), Positives = 83/202 (41%), Gaps = 31/202 (15%)

Query: 71  QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 130
           ++ER K +G +L  S  E    +   E  L ++     ++  +++   +    E  + +K
Sbjct: 397 RKERLKKEGKLLTKSQRE---ARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKK 453

Query: 131 IPLSGSNQEIRRQKE-----RITEQ----------PLKEEEDEDRKNKGHQAAEIEWLGF 175
           IP    ++E+    E      + EQ          P++ EE+ED ++ G      +W   
Sbjct: 454 IPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLD----DWEAM 509

Query: 176 RKPSQADMLHSKH---------DEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEV 226
               + + +             +EE++  +EE +D++ +    +E E    E  ++ E+V
Sbjct: 510 ASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKV 569

Query: 227 SQFKEEGDASEDSPLSSASSQA 248
           S  K+ G   +  P    SS +
Sbjct: 570 SDEKDSGKTLDKKPSKEMSSDS 591



 Score = 29.3 bits (64), Expect = 4.4
 Identities = 27/138 (19%), Positives = 65/138 (47%), Gaps = 12/138 (8%)

Query: 137 NQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWL--GFRKPSQADMLHSKHDEEQ-- 192
           N+  +++K++  ++  KEE+++++K KG   A ++ +     K  + +    + +EE+  
Sbjct: 309 NEGDKKKKDKKKKKGEKEEKEKEKK-KGPSKATVKAMQEALAKLKEEEERQKREEEERIK 367

Query: 193 -------KVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSAS 245
                  K  +EE  + +       +++ R    KK+ + +++ + E  A  ++ L    
Sbjct: 368 RLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQ 427

Query: 246 SQAVTPDEQPTLGKKSDI 263
           +Q V    + +L KK  I
Sbjct: 428 AQGVEVPSKDSLPKKRPI 445


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 36/160 (22%), Positives = 66/160 (41%), Gaps = 11/160 (6%)

Query: 90  KMLKENPEEKLFIVHKAITDLSLQ-ETSADEMTFREGHQWEKIPLSGSNQEIRRQKERIT 148
           K     P +K     KA+T    +  T    +    G +   IP  G+      +KE   
Sbjct: 87  KKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAAIPAKGAKNGKNAKKEDSD 146

Query: 149 EQPL--KEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDN 206
           E+     EE++ED +++     EIE    +  + A     + DE+ +  +++ DD++DD+
Sbjct: 147 EEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDS 206

Query: 207 CN--------NDEDEVRVIEFKKKHEEVSQFKEEGDASED 238
                       +   +V+  K K+    + +EE D  ED
Sbjct: 207 EEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDED 246



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 10/83 (12%)

Query: 149 EQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCN 208
           E   +EE  E    KG +AA++       P +A  +    DEE+   DE+ DDD+DD  +
Sbjct: 203 EDDSEEEAMETTPAKGKKAAKVV------PVKAKNVAEDEDEEEDDEDEDDDDDEDDEDD 256

Query: 209 NDEDEVRVIEFKKKHEEVSQFKE 231
           +DED+    E +++ EE    KE
Sbjct: 257 DDEDD----EEEEEEEEEEPVKE 275



 Score = 33.5 bits (75), Expect = 0.23
 Identities = 18/88 (20%), Positives = 48/88 (54%), Gaps = 6/88 (6%)

Query: 153 KEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDED 212
           ++++D++  +   +A E      +K ++   + +K+  E +  +E+ +D+DDD+  +DED
Sbjct: 196 EDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDED 255

Query: 213 EVRVIEFKKKHEEVSQFKEEGDASEDSP 240
           +        + +E  + +EE +  +++P
Sbjct: 256 D------DDEDDEEEEEEEEEEPVKEAP 277


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 34/143 (23%), Positives = 57/143 (39%), Gaps = 30/143 (20%)

Query: 155  EEDEDRKNKGHQAAEIEWLGFRKPSQAD-------------MLHSKHDEEQKVWDEEIDD 201
            EEDED   +  +A E    G + P + +              L S+ +E  +    E D+
Sbjct: 919  EEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDE 978

Query: 202  DDDDNCNNDEDEVRVIEFKKKHEEVSQFKE-----------------EGDASEDSPLSSA 244
            +DD+    DED    ++  KK  EVS  ++                 E D++ DS  SS+
Sbjct: 979  EDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSS 1038

Query: 245  SSQAVTPDEQPTLGKKSDISRNA 267
            SS + +     +    S  S ++
Sbjct: 1039 SSSSSSSSSSSSSSSSSSSSESS 1061


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 33/109 (30%), Positives = 52/109 (47%), Gaps = 20/109 (18%)

Query: 140  IRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEI 199
            +RR+  R  E     EEDE                  K S ++   S  +EE+   +EE 
Sbjct: 1019 VRRRPARPLELDSGGEEDE------------------KESLSEEQESTEEEEEAEEEEEE 1060

Query: 200  DDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQA 248
            +DDDDD+ ++D DE    +      E S+ K+EGD+ E+  +S  +S+A
Sbjct: 1061 EDDDDDD-SDDRDESENDDEDTALSEASE-KDEGDSDEEETVSIVTSKA 1107



 Score = 32.0 bits (71), Expect = 0.67
 Identities = 35/176 (19%), Positives = 69/176 (39%), Gaps = 45/176 (25%)

Query: 125  GHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADML 184
            G + EK  LS   +    ++E   E+  ++++D+D  ++     + E     + S+ D  
Sbjct: 1033 GEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKD-- 1090

Query: 185  HSKHDEEQKVW------------------DEEIDDDDDDNCNNDEDEVRVIEFKKKHEEV 226
                DEE+ V                   + E   +   + + DE+EV   E +++ EE 
Sbjct: 1091 EGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEE 1150

Query: 227  SQFKEEGDAS----------EDSPLSSAS---------------SQAVTPDEQPTL 257
                EE  AS          E++ L+  +               ++AV P+E+P++
Sbjct: 1151 EMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSM 1206


>gi|9257192 adducin 2 isoform a [Homo sapiens]
          Length = 726

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 40/149 (26%), Positives = 65/149 (43%), Gaps = 19/149 (12%)

Query: 114 ETSADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQA---AEI 170
           E S+  M  R  +  + +PL    QE+   + +I EQ       +D K+ G Q+   A +
Sbjct: 469 EKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQ-----NRQDVKSAGPQSQLLASV 523

Query: 171 EWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFK 230
                R PS    L SK DE+ K       DD ++   N   ++   E ++  +EV + K
Sbjct: 524 IAEKSRSPSTESQLMSKGDEDTK-------DDSEETVPNPFSQLTDQELEEYKKEVERKK 576

Query: 231 EEGDASEDS----PLSSASSQAVTPDEQP 255
            E D  +++    P S A S   +P + P
Sbjct: 577 LELDGEKETAPEEPGSPAKSAPASPVQSP 605


>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
          Length = 1184

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 29/121 (23%), Positives = 59/121 (48%), Gaps = 17/121 (14%)

Query: 154 EEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDE 213
           E+ DE  +++G + +E       +P   D    + D E++   EE D+DDD++  + EDE
Sbjct: 97  EDMDEKEEDEGEEYSEDN----DEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDE 152

Query: 214 VRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSDISRNAYSRYNT 273
                  ++ EE  + +EE + +ED  ++  +++ +   E      K D + + Y  Y+ 
Sbjct: 153 -------EEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTE------KDDNNNDEYDNYDE 199

Query: 274 I 274
           +
Sbjct: 200 L 200



 Score = 28.5 bits (62), Expect = 7.4
 Identities = 25/116 (21%), Positives = 54/116 (46%), Gaps = 20/116 (17%)

Query: 149 EQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCN 208
           E+  +EEE+E+ +N+ HQ                   + H+       E+ D+++D+  N
Sbjct: 155 EEEEEEEEEEEEENEDHQM------------------NCHNTRIMQDTEKDDNNNDEYDN 196

Query: 209 NDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSDIS 264
            DE   + +    K  E + ++   ++  +S  ++++S     D+   LG+KS++S
Sbjct: 197 YDELVAKSLLNLGKIAEDAAYRARTESEMNS--NTSNSLEDDSDKNENLGRKSELS 250


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.126    0.352 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,399,154
Number of Sequences: 37866
Number of extensions: 622361
Number of successful extensions: 6020
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 137
Number of HSP's successfully gapped in prelim test: 353
Number of HSP's that attempted gapping in prelim test: 3626
Number of HSP's gapped (non-prelim): 1461
length of query: 297
length of database: 18,247,518
effective HSP length: 102
effective length of query: 195
effective length of database: 14,385,186
effective search space: 2805111270
effective search space used: 2805111270
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press