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Search of human proteins with 58082081
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|58082081 phosphoinositide-3-kinase, regulatory subunit 6
[Homo sapiens]
(754 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|58082081 phosphoinositide-3-kinase, regulatory subunit 6 [Hom... 1508 0.0
gi|217330639 phosphoinositide-3-kinase, regulatory subunit 5 [Ho... 119 1e-26
gi|217330622 phosphoinositide-3-kinase, regulatory subunit 5 [Ho... 119 1e-26
gi|115430245 arylhydrocarbon receptor repressor [Homo sapiens] 34 0.44
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 34 0.44
gi|154816198 transcription elongation factor B polypeptide 3C-li... 32 1.7
gi|156938279 transcription elongation factor B polypeptide 3C [H... 32 1.7
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 32 2.2
gi|31652238 cut-like homeobox 1 isoform c [Homo sapiens] 32 2.8
gi|31652236 cut-like homeobox 1 isoform b [Homo sapiens] 32 2.8
gi|146219832 myosin light chain kinase 3 [Homo sapiens] 31 3.7
gi|239755722 PREDICTED: hypothetical protein [Homo sapiens] 31 4.8
gi|169218211 PREDICTED: similar to plectin 1, partial [Homo sapi... 31 4.8
gi|239750240 PREDICTED: hypothetical protein [Homo sapiens] 31 4.8
gi|239744540 PREDICTED: hypothetical protein XP_002343179 [Homo ... 31 4.8
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 31 4.8
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 31 4.8
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 31 4.8
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 31 4.8
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 31 4.8
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 31 4.8
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 31 4.8
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 31 4.8
gi|110815838 dysbindin (dystrobrevin binding protein 1) domain c... 30 6.3
gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo ... 30 6.3
gi|169162915 PREDICTED: hypothetical protein LOC728841 [Homo sap... 30 6.3
gi|156151427 OPA3 protein isoform a [Homo sapiens] 30 6.3
gi|21704281 junctophilin 2 isoform 1 [Homo sapiens] 30 6.3
gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens] 30 8.3
gi|23111032 sorting nexin 1 isoform b [Homo sapiens] 30 8.3
>gi|58082081 phosphoinositide-3-kinase, regulatory subunit 6 [Homo
sapiens]
Length = 754
Score = 1508 bits (3905), Expect = 0.0
Identities = 754/754 (100%), Positives = 754/754 (100%)
Query: 1 MESSDVELDLQRSVQAVLRELSTQAPALQSNQGMWRWSLHKKVERDPGKSPVLVRILLRE 60
MESSDVELDLQRSVQAVLRELSTQAPALQSNQGMWRWSLHKKVERDPGKSPVLVRILLRE
Sbjct: 1 MESSDVELDLQRSVQAVLRELSTQAPALQSNQGMWRWSLHKKVERDPGKSPVLVRILLRE 60
Query: 61 LEKAESQDLRHVIIPLLHTVMYVLTKATGITEELYQRIYAFCTRLLTLPTPYCTVALDCA 120
LEKAESQDLRHVIIPLLHTVMYVLTKATGITEELYQRIYAFCTRLLTLPTPYCTVALDCA
Sbjct: 61 LEKAESQDLRHVIIPLLHTVMYVLTKATGITEELYQRIYAFCTRLLTLPTPYCTVALDCA 120
Query: 121 IRLKTEMAVPGTLYQRMVIAEQNLTNELYPYQERVFLFVDPELVSASVCSALLLEIEAAQ 180
IRLKTEMAVPGTLYQRMVIAEQNLTNELYPYQERVFLFVDPELVSASVCSALLLEIEAAQ
Sbjct: 121 IRLKTEMAVPGTLYQRMVIAEQNLTNELYPYQERVFLFVDPELVSASVCSALLLEIEAAQ 180
Query: 181 AQQTPETCMRHVVSHALQAALGEACHAGALHRKLQASPRRTLEHYFHAVVAALEQMASEA 240
AQQTPETCMRHVVSHALQAALGEACHAGALHRKLQASPRRTLEHYFHAVVAALEQMASEA
Sbjct: 181 AQQTPETCMRHVVSHALQAALGEACHAGALHRKLQASPRRTLEHYFHAVVAALEQMASEA 240
Query: 241 SPSREGHVERLEEIYCSLLGPAAGRCGGDLVQERPPSIPLPSPYITFHLWTGEEQLWKEL 300
SPSREGHVERLEEIYCSLLGPAAGRCGGDLVQERPPSIPLPSPYITFHLWTGEEQLWKEL
Sbjct: 241 SPSREGHVERLEEIYCSLLGPAAGRCGGDLVQERPPSIPLPSPYITFHLWTGEEQLWKEL 300
Query: 301 VLFLRPRSQLRLSADLEVLDLQGLRPDRELARVSVLSTDSGIERDLPTGADELPAPGSPE 360
VLFLRPRSQLRLSADLEVLDLQGLRPDRELARVSVLSTDSGIERDLPTGADELPAPGSPE
Sbjct: 301 VLFLRPRSQLRLSADLEVLDLQGLRPDRELARVSVLSTDSGIERDLPTGADELPAPGSPE 360
Query: 361 MERAGLQRKGGIKKRAWPLDFLMPGSWDGPPGLHRRTGRPSGDGEMLPGVSRLHTARVLV 420
MERAGLQRKGGIKKRAWPLDFLMPGSWDGPPGLHRRTGRPSGDGEMLPGVSRLHTARVLV
Sbjct: 361 MERAGLQRKGGIKKRAWPLDFLMPGSWDGPPGLHRRTGRPSGDGEMLPGVSRLHTARVLV 420
Query: 421 LGDDRMLGRLAQAYHRLRKRETQKFCLTPRLSLQLYYIPVLAPEKPAASRQPELGELATF 480
LGDDRMLGRLAQAYHRLRKRETQKFCLTPRLSLQLYYIPVLAPEKPAASRQPELGELATF
Sbjct: 421 LGDDRMLGRLAQAYHRLRKRETQKFCLTPRLSLQLYYIPVLAPEKPAASRQPELGELATF 480
Query: 481 LGRVDPWYQSNVNTLCPAIHKLAEMPPSLDTSRTVDPFILDVITYYIRMGTQPIYFQIYT 540
LGRVDPWYQSNVNTLCPAIHKLAEMPPSLDTSRTVDPFILDVITYYIRMGTQPIYFQIYT
Sbjct: 481 LGRVDPWYQSNVNTLCPAIHKLAEMPPSLDTSRTVDPFILDVITYYIRMGTQPIYFQIYT 540
Query: 541 VKIFFSDLSQDPTEDIFLIELKVKIQDSKFPKDGFSPRRRGVAEGPGAELSLCYQKALLS 600
VKIFFSDLSQDPTEDIFLIELKVKIQDSKFPKDGFSPRRRGVAEGPGAELSLCYQKALLS
Sbjct: 541 VKIFFSDLSQDPTEDIFLIELKVKIQDSKFPKDGFSPRRRGVAEGPGAELSLCYQKALLS 600
Query: 601 HRPREVTVSLRATGLILKAIPASDTEVSGSSHCPLPAAPVTDHTCLNVNVTEVVKSSNLA 660
HRPREVTVSLRATGLILKAIPASDTEVSGSSHCPLPAAPVTDHTCLNVNVTEVVKSSNLA
Sbjct: 601 HRPREVTVSLRATGLILKAIPASDTEVSGSSHCPLPAAPVTDHTCLNVNVTEVVKSSNLA 660
Query: 661 GKSFSTVTNTFRTNNIQIQSRDQRLLTLSLDKDDQRTFRDVVRFEVAPCPEPCSGAQKSK 720
GKSFSTVTNTFRTNNIQIQSRDQRLLTLSLDKDDQRTFRDVVRFEVAPCPEPCSGAQKSK
Sbjct: 661 GKSFSTVTNTFRTNNIQIQSRDQRLLTLSLDKDDQRTFRDVVRFEVAPCPEPCSGAQKSK 720
Query: 721 APWLNLHGQQEVEAIKAKPKPLLMPINTFSGIVQ 754
APWLNLHGQQEVEAIKAKPKPLLMPINTFSGIVQ
Sbjct: 721 APWLNLHGQQEVEAIKAKPKPLLMPINTFSGIVQ 754
>gi|217330639 phosphoinositide-3-kinase, regulatory subunit 5 [Homo
sapiens]
Length = 880
Score = 119 bits (298), Expect = 1e-26
Identities = 115/415 (27%), Positives = 174/415 (41%), Gaps = 76/415 (18%)
Query: 386 SWDGPPGLHRRTGRPSGDGEMLPGVSRLHTARVLVLGDDRMLGRLAQAYHRLRKRETQKF 445
SW P + RP G+ P S T RV+V G DR+ G++A+AY LR+ E +
Sbjct: 490 SWLLAPASRPQRRRPFLSGDEDPKAS---TLRVVVFGSDRISGKVARAYSNLRRLENNRP 546
Query: 446 CLTPRLSLQLYYIPV----------------LAPEKPAAS-RQPELGELAT--------- 479
LT LQ +Y+PV P P S R GEL T
Sbjct: 547 LLTRFFKLQFFYVPVKRSHGTSPGACPPPRSQTPSPPTDSPRHASPGELGTTPWEESTND 606
Query: 480 ---FLGRVDPWYQSNV--------NTLCPAIHKLAEMPPSLDTSRTVDPFILDVITYYIR 528
+LG +DPWY+ NV LC L +L+ S T P + D++ YY R
Sbjct: 607 ISHYLGMLDPWYERNVLGLMHLPPEVLCQ--QSLKAEAQALEGSPTQLPILADMLLYYCR 664
Query: 529 MGTQPIYFQIYTVKIFFSDLSQDPTEDIFL--IELKVKIQDSKFPKDGFSPRRRGV---A 583
+P+ Q+Y ++ F ++ + T +IF+ +EL G +R G+
Sbjct: 665 FAARPVLLQVYQTELTF--ITGEKTTEIFIHSLELGHSAATRAIKASGPGSKRLGIDGDR 722
Query: 584 EGPGAELSLCYQKALLSHRPREVTVSLRATGLILKAIPASDTEVSGSSHCPLPAAPVTDH 643
E L + Y K +S R R + T + L E+ S
Sbjct: 723 EAVPLTLQIIYSKGAISGRSRWSNLEKVCTSVNLNKACRKQEELDSSME----------- 771
Query: 644 TCLNVNVTEVVKSSN-LAGKSFSTV-TNTFRTNNIQIQSRDQRLLTLSLDKDDQRTFRDV 701
L +N+TEVVK N + K F+ + T+ + + +QI + + LD+D+++ + V
Sbjct: 772 -ALTLNLTEVVKRQNSKSKKGFNQISTSQIKVDKVQIIGSNSCPFAVCLDQDERKILQSV 830
Query: 702 VRFEVAPCPEPCSGAQKSKAPWLNLHGQQEVEAIKAKPKP-----LLMPINTFSG 751
VR EV+PC +P + S P Q + A+ P L +PI TFSG
Sbjct: 831 VRCEVSPCYKP-EKSDLSSPP-------QTPPDLPAQAAPDLCSLLCLPIMTFSG 877
Score = 78.6 bits (192), Expect = 2e-14
Identities = 60/229 (26%), Positives = 99/229 (43%), Gaps = 7/229 (3%)
Query: 10 LQRSVQAVLRELSTQAPALQSNQGMWR--WSLHKKVERDPGKSPVLVRILLRELEKAESQ 67
+Q +++ L LS + + G+ WSL + V RDPG +L+ +L++ + + +
Sbjct: 13 IQHALERCLHGLSLSRRSTSWSAGLCLNCWSLQELVSRDPGHFLILLEQILQKTREVQEK 72
Query: 68 DLRHVIIPL--LHTVMYVLTKATGITEELYQRIYAFCTRLLTLPTPYCTVALDCAIRLKT 125
++ PL L + T +L + + R LT P PYC++ + +
Sbjct: 73 GTYDLLTPLALLFYSTVLCTPHFPPDSDLLLKAASTYHRFLTWPVPYCSICQELLTFIDA 132
Query: 126 EMAVPGTLYQRMVIAEQNLTNELYPYQERVFLFVDPELVSASVCSALLLEIEAAQAQQTP 185
E+ PG YQR+V AEQ L + L ++P V A L + + + +P
Sbjct: 133 ELKAPGISYQRLVRAEQGLPIRSHRSSTVTVLLLNPVEVQAEF---LAVANKLSTPGHSP 189
Query: 186 ETCMRHVVSHALQAALGEACHAGALHRKLQASPRRTLEHYFHAVVAALE 234
+ ++ HA QA G C LH +LQA LE F A E
Sbjct: 190 HSAYTTLLLHAFQATFGAHCDVPGLHCRLQAKTLAELEDIFTETAEAQE 238
>gi|217330622 phosphoinositide-3-kinase, regulatory subunit 5 [Homo
sapiens]
Length = 880
Score = 119 bits (298), Expect = 1e-26
Identities = 115/415 (27%), Positives = 174/415 (41%), Gaps = 76/415 (18%)
Query: 386 SWDGPPGLHRRTGRPSGDGEMLPGVSRLHTARVLVLGDDRMLGRLAQAYHRLRKRETQKF 445
SW P + RP G+ P S T RV+V G DR+ G++A+AY LR+ E +
Sbjct: 490 SWLLAPASRPQRRRPFLSGDEDPKAS---TLRVVVFGSDRISGKVARAYSNLRRLENNRP 546
Query: 446 CLTPRLSLQLYYIPV----------------LAPEKPAAS-RQPELGELAT--------- 479
LT LQ +Y+PV P P S R GEL T
Sbjct: 547 LLTRFFKLQFFYVPVKRSHGTSPGACPPPRSQTPSPPTDSPRHASPGELGTTPWEESTND 606
Query: 480 ---FLGRVDPWYQSNV--------NTLCPAIHKLAEMPPSLDTSRTVDPFILDVITYYIR 528
+LG +DPWY+ NV LC L +L+ S T P + D++ YY R
Sbjct: 607 ISHYLGMLDPWYERNVLGLMHLPPEVLCQ--QSLKAEAQALEGSPTQLPILADMLLYYCR 664
Query: 529 MGTQPIYFQIYTVKIFFSDLSQDPTEDIFL--IELKVKIQDSKFPKDGFSPRRRGV---A 583
+P+ Q+Y ++ F ++ + T +IF+ +EL G +R G+
Sbjct: 665 FAARPVLLQVYQTELTF--ITGEKTTEIFIHSLELGHSAATRAIKASGPGSKRLGIDGDR 722
Query: 584 EGPGAELSLCYQKALLSHRPREVTVSLRATGLILKAIPASDTEVSGSSHCPLPAAPVTDH 643
E L + Y K +S R R + T + L E+ S
Sbjct: 723 EAVPLTLQIIYSKGAISGRSRWSNLEKVCTSVNLNKACRKQEELDSSME----------- 771
Query: 644 TCLNVNVTEVVKSSN-LAGKSFSTV-TNTFRTNNIQIQSRDQRLLTLSLDKDDQRTFRDV 701
L +N+TEVVK N + K F+ + T+ + + +QI + + LD+D+++ + V
Sbjct: 772 -ALTLNLTEVVKRQNSKSKKGFNQISTSQIKVDKVQIIGSNSCPFAVCLDQDERKILQSV 830
Query: 702 VRFEVAPCPEPCSGAQKSKAPWLNLHGQQEVEAIKAKPKP-----LLMPINTFSG 751
VR EV+PC +P + S P Q + A+ P L +PI TFSG
Sbjct: 831 VRCEVSPCYKP-EKSDLSSPP-------QTPPDLPAQAAPDLCSLLCLPIMTFSG 877
Score = 78.6 bits (192), Expect = 2e-14
Identities = 60/229 (26%), Positives = 99/229 (43%), Gaps = 7/229 (3%)
Query: 10 LQRSVQAVLRELSTQAPALQSNQGMWR--WSLHKKVERDPGKSPVLVRILLRELEKAESQ 67
+Q +++ L LS + + G+ WSL + V RDPG +L+ +L++ + + +
Sbjct: 13 IQHALERCLHGLSLSRRSTSWSAGLCLNCWSLQELVSRDPGHFLILLEQILQKTREVQEK 72
Query: 68 DLRHVIIPL--LHTVMYVLTKATGITEELYQRIYAFCTRLLTLPTPYCTVALDCAIRLKT 125
++ PL L + T +L + + R LT P PYC++ + +
Sbjct: 73 GTYDLLTPLALLFYSTVLCTPHFPPDSDLLLKAASTYHRFLTWPVPYCSICQELLTFIDA 132
Query: 126 EMAVPGTLYQRMVIAEQNLTNELYPYQERVFLFVDPELVSASVCSALLLEIEAAQAQQTP 185
E+ PG YQR+V AEQ L + L ++P V A L + + + +P
Sbjct: 133 ELKAPGISYQRLVRAEQGLPIRSHRSSTVTVLLLNPVEVQAEF---LAVANKLSTPGHSP 189
Query: 186 ETCMRHVVSHALQAALGEACHAGALHRKLQASPRRTLEHYFHAVVAALE 234
+ ++ HA QA G C LH +LQA LE F A E
Sbjct: 190 HSAYTTLLLHAFQATFGAHCDVPGLHCRLQAKTLAELEDIFTETAEAQE 238
>gi|115430245 arylhydrocarbon receptor repressor [Homo sapiens]
Length = 719
Score = 34.3 bits (77), Expect = 0.44
Identities = 35/99 (35%), Positives = 42/99 (42%), Gaps = 18/99 (18%)
Query: 310 LRLSADLEVLDLQGLRPDRELARVSVLSTDSGIERDLPTGADELPAPGSPEMERAGLQRK 369
LR DL VLD +G DRE + +LS SG+ TG E P P P AG +
Sbjct: 378 LRGGPDL-VLDPKGGSGDREEEQHRMLSRASGV-----TGRRETPGPTKPLPWTAGKHSE 431
Query: 370 GGIKKRAWPLDFLMPGSWDGPPGLHRRTGRPSGDGEMLP 408
G + R P S + PP L RP G LP
Sbjct: 432 DGARPRLQP-------SKNDPPSL-----RPMPRGSCLP 458
>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
sapiens]
Length = 1691
Score = 34.3 bits (77), Expect = 0.44
Identities = 29/74 (39%), Positives = 33/74 (44%), Gaps = 14/74 (18%)
Query: 347 PTGADELPAPGSPEMERAGLQRKGGIK-KRAWPLDFLMPG-----SWDGPPGLHRRTGRP 400
PTG LP P P GL GGIK ++ P +PG GPPGL GRP
Sbjct: 1265 PTGFQGLPGPEGPP----GLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRP 1320
Query: 401 SGDGEM----LPGV 410
+G LPGV
Sbjct: 1321 GLNGMKGDPGLPGV 1334
>gi|154816198 transcription elongation factor B polypeptide 3C-like
[Homo sapiens]
Length = 546
Score = 32.3 bits (72), Expect = 1.7
Identities = 40/164 (24%), Positives = 55/164 (33%), Gaps = 6/164 (3%)
Query: 326 PDRELARVSVLSTDSGIERDLPTGADELPAPGSPEMERAGLQRKGGIKKRAWPLDFLMPG 385
P E R + DSG RD PT LP P PE G Q G A L G
Sbjct: 151 PRAERKRPRMAPADSGPHRDPPTRTAPLPMPEGPEPAVPGEQPGRGHAHAAQGGPLLGQG 210
Query: 386 SWDGPP----GLHRRTGRPS--GDGEMLPGVSRLHTARVLVLGDDRMLGRLAQAYHRLRK 439
P G H + + S + P V + R+ G D + ++
Sbjct: 211 CQGQPQGEAVGSHSKGHKSSRGASAQKSPPVQESQSERLQAAGADSAGPKTVPSHVFSEL 270
Query: 440 RETQKFCLTPRLSLQLYYIPVLAPEKPAASRQPELGELATFLGR 483
+ + + L + + + P A P L E A F GR
Sbjct: 271 WDPSEAWMQANYDLLSAFEAMTSQANPEALSAPTLQEEAAFPGR 314
>gi|156938279 transcription elongation factor B polypeptide 3C [Homo
sapiens]
Length = 546
Score = 32.3 bits (72), Expect = 1.7
Identities = 40/164 (24%), Positives = 55/164 (33%), Gaps = 6/164 (3%)
Query: 326 PDRELARVSVLSTDSGIERDLPTGADELPAPGSPEMERAGLQRKGGIKKRAWPLDFLMPG 385
P E R + DSG RD PT LP P PE G Q G A L G
Sbjct: 151 PRAERKRPRMAPADSGPHRDPPTRTAPLPMPEGPEPAVPGEQPGRGHAHAAQGGPLLGQG 210
Query: 386 SWDGPP----GLHRRTGRPS--GDGEMLPGVSRLHTARVLVLGDDRMLGRLAQAYHRLRK 439
P G H + + S + P V + R+ G D + ++
Sbjct: 211 CQGQPQGEAVGSHSKGHKSSRGASAQKSPPVQESQSERLQAAGADSAGPKTVPSHVFSEL 270
Query: 440 RETQKFCLTPRLSLQLYYIPVLAPEKPAASRQPELGELATFLGR 483
+ + + L + + + P A P L E A F GR
Sbjct: 271 WDPSEAWMQANYDLLSAFEAMTSQANPEALSAPALQEEAAFPGR 314
>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
sapiens]
Length = 1685
Score = 32.0 bits (71), Expect = 2.2
Identities = 28/74 (37%), Positives = 32/74 (43%), Gaps = 14/74 (18%)
Query: 347 PTGADELPAPGSPEMERAGLQRKGGIK-KRAWPLDFLMPG-----SWDGPPGLHRRTGRP 400
P G LP P P GL GGIK ++ P +PG GPPGL GRP
Sbjct: 1259 PPGRPGLPGPEGPP----GLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRP 1314
Query: 401 SGDGEM----LPGV 410
+G LPGV
Sbjct: 1315 GLNGMKGDPGLPGV 1328
>gi|31652238 cut-like homeobox 1 isoform c [Homo sapiens]
Length = 676
Score = 31.6 bits (70), Expect = 2.8
Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 18/116 (15%)
Query: 14 VQAVLRELSTQAPALQSNQGMWRWSLHKKVERDPGKSPVLVRILLRELEKAESQDLRHVI 73
+Q + REL A L + Q S + +E+ RE +K +DLR +
Sbjct: 17 LQQLQRELDATATVLANRQDESEQSRKRLIEQS------------REFKKNTPEDLRKQV 64
Query: 74 IPLLHTV---MYVLTKATGITEELYQRIYAFCTRLLTLPTPYCTVALDCAIRLKTE 126
PLL + + L+K + E + +Y RL+ +P P + L ++LK +
Sbjct: 65 APLLKSFQGEIDALSKRSKEAEAAFLNVY---KRLIDVPDPVPALDLGQQLQLKVQ 117
>gi|31652236 cut-like homeobox 1 isoform b [Homo sapiens]
Length = 678
Score = 31.6 bits (70), Expect = 2.8
Identities = 29/116 (25%), Positives = 50/116 (43%), Gaps = 18/116 (15%)
Query: 14 VQAVLRELSTQAPALQSNQGMWRWSLHKKVERDPGKSPVLVRILLRELEKAESQDLRHVI 73
+Q + REL A L + Q S + +E+ RE +K +DLR +
Sbjct: 17 LQQLQRELDATATVLANRQDESEQSRKRLIEQS------------REFKKNTPEDLRKQV 64
Query: 74 IPLLHTV---MYVLTKATGITEELYQRIYAFCTRLLTLPTPYCTVALDCAIRLKTE 126
PLL + + L+K + E + +Y RL+ +P P + L ++LK +
Sbjct: 65 APLLKSFQGEIDALSKRSKEAEAAFLNVY---KRLIDVPDPVPALDLGQQLQLKVQ 117
>gi|146219832 myosin light chain kinase 3 [Homo sapiens]
Length = 819
Score = 31.2 bits (69), Expect = 3.7
Identities = 31/98 (31%), Positives = 40/98 (40%), Gaps = 14/98 (14%)
Query: 345 DLPTGADELPAPG-----SPEMERAGLQRKGGIKKRAWPLDF-----LMPG---SWDGPP 391
+L TG + PAPG SP +E A +G R P L PG GPP
Sbjct: 257 NLRTGLELAPAPGRVNVVSPSLEVAPGAGQGASSSRPDPEPLEEGTRLTPGPGPQCPGPP 316
Query: 392 GLHRRTGRPSGDGEMLPGVSRLHTARVLVLGDDRMLGR 429
GL + GE P +S +H + G+ M GR
Sbjct: 317 GLPAQARATHSGGETPPRIS-IHIQEMDTPGEMLMTGR 353
>gi|239755722 PREDICTED: hypothetical protein [Homo sapiens]
Length = 164
Score = 30.8 bits (68), Expect = 4.8
Identities = 32/111 (28%), Positives = 40/111 (36%), Gaps = 11/111 (9%)
Query: 321 LQGLRPDREL------ARVSVLSTDSGIERDLPTGADELPAPGSPEMERAGLQRKGGIKK 374
++GL P R L R G+E DL + ELPA P + R G GG +
Sbjct: 3 IEGLAPSRRLLAPACPCRTPPFQKKVGLEGDLAGRSLELPAGAQPHLRRLG---AGG--R 57
Query: 375 RAWPLDFLMPGSWDGPPGLHRRTGRPSGDGEMLPGVSRLHTARVLVLGDDR 425
A P S + R T S GV RL A +L R
Sbjct: 58 AAGPQSASSMSSRQPSRSMSRSTRPSSSSVASRRGVRRLQVASMLYCASRR 108
>gi|169218211 PREDICTED: similar to plectin 1, partial [Homo
sapiens]
Length = 1369
Score = 30.8 bits (68), Expect = 4.8
Identities = 27/101 (26%), Positives = 45/101 (44%), Gaps = 12/101 (11%)
Query: 48 GKSPVLVRILLRELEKAESQDLRHVIIPLLHTVMYVLTKATGITEELYQRIYAFCTRLLT 107
GK P + R+L+KA+S +I L + V + E++Y+R+Y RL+
Sbjct: 562 GKVPQRAGEVERDLDKADS-----MIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVA 616
Query: 108 LPTPYCTVALDCAIRLKTEMAVPGTLYQRMVIAEQNLTNEL 148
+ T Y +RLK +A P T ++ + EL
Sbjct: 617 IRTEY-------NLRLKAGVAAPATQVAQVTLQSVQRRPEL 650
>gi|239750240 PREDICTED: hypothetical protein [Homo sapiens]
Length = 164
Score = 30.8 bits (68), Expect = 4.8
Identities = 32/111 (28%), Positives = 40/111 (36%), Gaps = 11/111 (9%)
Query: 321 LQGLRPDREL------ARVSVLSTDSGIERDLPTGADELPAPGSPEMERAGLQRKGGIKK 374
++GL P R L R G+E DL + ELPA P + R G GG +
Sbjct: 3 IEGLAPSRRLLAPACPCRTPPFQKKVGLEGDLAGRSLELPAGAQPHLRRLG---AGG--R 57
Query: 375 RAWPLDFLMPGSWDGPPGLHRRTGRPSGDGEMLPGVSRLHTARVLVLGDDR 425
A P S + R T S GV RL A +L R
Sbjct: 58 AAGPQSASSMSSRQPSRSMSRSTRPSSSSVASRRGVRRLQVASMLYCASRR 108
>gi|239744540 PREDICTED: hypothetical protein XP_002343179 [Homo
sapiens]
Length = 164
Score = 30.8 bits (68), Expect = 4.8
Identities = 32/111 (28%), Positives = 40/111 (36%), Gaps = 11/111 (9%)
Query: 321 LQGLRPDREL------ARVSVLSTDSGIERDLPTGADELPAPGSPEMERAGLQRKGGIKK 374
++GL P R L R G+E DL + ELPA P + R G GG +
Sbjct: 3 IEGLAPSRRLLAPACPCRTPPFQKKVGLEGDLAGRSLELPAGAQPHLRRLG---AGG--R 57
Query: 375 RAWPLDFLMPGSWDGPPGLHRRTGRPSGDGEMLPGVSRLHTARVLVLGDDR 425
A P S + R T S GV RL A +L R
Sbjct: 58 AAGPQSASSMSSRQPSRSMSRSTRPSSSSVASRRGVRRLQVASMLYCASRR 108
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 30.8 bits (68), Expect = 4.8
Identities = 27/101 (26%), Positives = 45/101 (44%), Gaps = 12/101 (11%)
Query: 48 GKSPVLVRILLRELEKAESQDLRHVIIPLLHTVMYVLTKATGITEELYQRIYAFCTRLLT 107
GK P + R+L+KA+S +I L + V + E++Y+R+Y RL+
Sbjct: 429 GKVPQRAGEVERDLDKADS-----MIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVA 483
Query: 108 LPTPYCTVALDCAIRLKTEMAVPGTLYQRMVIAEQNLTNEL 148
+ T Y +RLK +A P T ++ + EL
Sbjct: 484 IRTEY-------NLRLKAGVAAPATQVAQVTLQSVQRRPEL 517
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 30.8 bits (68), Expect = 4.8
Identities = 27/101 (26%), Positives = 45/101 (44%), Gaps = 12/101 (11%)
Query: 48 GKSPVLVRILLRELEKAESQDLRHVIIPLLHTVMYVLTKATGITEELYQRIYAFCTRLLT 107
GK P + R+L+KA+S +I L + V + E++Y+R+Y RL+
Sbjct: 433 GKVPQRAGEVERDLDKADS-----MIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVA 487
Query: 108 LPTPYCTVALDCAIRLKTEMAVPGTLYQRMVIAEQNLTNEL 148
+ T Y +RLK +A P T ++ + EL
Sbjct: 488 IRTEY-------NLRLKAGVAAPATQVAQVTLQSVQRRPEL 521
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 30.8 bits (68), Expect = 4.8
Identities = 27/101 (26%), Positives = 45/101 (44%), Gaps = 12/101 (11%)
Query: 48 GKSPVLVRILLRELEKAESQDLRHVIIPLLHTVMYVLTKATGITEELYQRIYAFCTRLLT 107
GK P + R+L+KA+S +I L + V + E++Y+R+Y RL+
Sbjct: 429 GKVPQRAGEVERDLDKADS-----MIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVA 483
Query: 108 LPTPYCTVALDCAIRLKTEMAVPGTLYQRMVIAEQNLTNEL 148
+ T Y +RLK +A P T ++ + EL
Sbjct: 484 IRTEY-------NLRLKAGVAAPATQVAQVTLQSVQRRPEL 517
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 30.8 bits (68), Expect = 4.8
Identities = 27/101 (26%), Positives = 45/101 (44%), Gaps = 12/101 (11%)
Query: 48 GKSPVLVRILLRELEKAESQDLRHVIIPLLHTVMYVLTKATGITEELYQRIYAFCTRLLT 107
GK P + R+L+KA+S +I L + V + E++Y+R+Y RL+
Sbjct: 397 GKVPQRAGEVERDLDKADS-----MIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVA 451
Query: 108 LPTPYCTVALDCAIRLKTEMAVPGTLYQRMVIAEQNLTNEL 148
+ T Y +RLK +A P T ++ + EL
Sbjct: 452 IRTEY-------NLRLKAGVAAPATQVAQVTLQSVQRRPEL 485
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 30.8 bits (68), Expect = 4.8
Identities = 27/101 (26%), Positives = 45/101 (44%), Gaps = 12/101 (11%)
Query: 48 GKSPVLVRILLRELEKAESQDLRHVIIPLLHTVMYVLTKATGITEELYQRIYAFCTRLLT 107
GK P + R+L+KA+S +I L + V + E++Y+R+Y RL+
Sbjct: 566 GKVPQRAGEVERDLDKADS-----MIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVA 620
Query: 108 LPTPYCTVALDCAIRLKTEMAVPGTLYQRMVIAEQNLTNEL 148
+ T Y +RLK +A P T ++ + EL
Sbjct: 621 IRTEY-------NLRLKAGVAAPATQVAQVTLQSVQRRPEL 654
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 30.8 bits (68), Expect = 4.8
Identities = 27/101 (26%), Positives = 45/101 (44%), Gaps = 12/101 (11%)
Query: 48 GKSPVLVRILLRELEKAESQDLRHVIIPLLHTVMYVLTKATGITEELYQRIYAFCTRLLT 107
GK P + R+L+KA+S +I L + V + E++Y+R+Y RL+
Sbjct: 407 GKVPQRAGEVERDLDKADS-----MIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVA 461
Query: 108 LPTPYCTVALDCAIRLKTEMAVPGTLYQRMVIAEQNLTNEL 148
+ T Y +RLK +A P T ++ + EL
Sbjct: 462 IRTEY-------NLRLKAGVAAPATQVAQVTLQSVQRRPEL 495
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 30.8 bits (68), Expect = 4.8
Identities = 27/101 (26%), Positives = 45/101 (44%), Gaps = 12/101 (11%)
Query: 48 GKSPVLVRILLRELEKAESQDLRHVIIPLLHTVMYVLTKATGITEELYQRIYAFCTRLLT 107
GK P + R+L+KA+S +I L + V + E++Y+R+Y RL+
Sbjct: 415 GKVPQRAGEVERDLDKADS-----MIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVA 469
Query: 108 LPTPYCTVALDCAIRLKTEMAVPGTLYQRMVIAEQNLTNEL 148
+ T Y +RLK +A P T ++ + EL
Sbjct: 470 IRTEY-------NLRLKAGVAAPATQVAQVTLQSVQRRPEL 503
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 30.8 bits (68), Expect = 4.8
Identities = 27/101 (26%), Positives = 45/101 (44%), Gaps = 12/101 (11%)
Query: 48 GKSPVLVRILLRELEKAESQDLRHVIIPLLHTVMYVLTKATGITEELYQRIYAFCTRLLT 107
GK P + R+L+KA+S +I L + V + E++Y+R+Y RL+
Sbjct: 456 GKVPQRAGEVERDLDKADS-----MIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVA 510
Query: 108 LPTPYCTVALDCAIRLKTEMAVPGTLYQRMVIAEQNLTNEL 148
+ T Y +RLK +A P T ++ + EL
Sbjct: 511 IRTEY-------NLRLKAGVAAPATQVAQVTLQSVQRRPEL 544
>gi|110815838 dysbindin (dystrobrevin binding protein 1) domain
containing 1 isoform 1 [Homo sapiens]
Length = 158
Score = 30.4 bits (67), Expect = 6.3
Identities = 34/118 (28%), Positives = 50/118 (42%), Gaps = 18/118 (15%)
Query: 246 GHVERLEEIYCSLLGPAA---GRCGGDLVQERPPSIPLPSPYITFHLWTGEEQLWKELVL 302
G + + E+ + LG A G G V+E IP+P+P + L E +
Sbjct: 10 GEIVKEAEVPQAALGVPAQGTGDNGHTPVEEEVGGIPVPAPGL---LQVTERR------- 59
Query: 303 FLRPRSQLR-LSADLEVLDLQGLRP--DRELARVSVLSTDSGIERDLPTGADELPAPG 357
+P S + L ++LDL L D+ELA V S D + + P G LP G
Sbjct: 60 --QPLSSVSSLEVHFDLLDLTELTDMSDQELAEVFADSDDENLNTESPAGLHPLPRAG 115
>gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo
sapiens]
Length = 4621
Score = 30.4 bits (67), Expect = 6.3
Identities = 22/82 (26%), Positives = 34/82 (41%), Gaps = 4/82 (4%)
Query: 551 DPTEDIFLIELKVKIQDSKFPKDGFSPRRRGVAEGPGAELSLCYQKALLSHRPREVTVSL 610
D ED+ +EL K+Q S P++ + V E E ++ Y SH P +
Sbjct: 440 DDDEDV-QVELAEKVQKSSAPREMQKAEEKEVPEDSQEECAITYSN---SHGPYDSNQPH 495
Query: 611 RATGLILKAIPASDTEVSGSSH 632
R T + + T + SSH
Sbjct: 496 RKTKITFEEDKVDSTLIGSSSH 517
>gi|169162915 PREDICTED: hypothetical protein LOC728841 [Homo
sapiens]
Length = 3815
Score = 30.4 bits (67), Expect = 6.3
Identities = 22/82 (26%), Positives = 34/82 (41%), Gaps = 4/82 (4%)
Query: 551 DPTEDIFLIELKVKIQDSKFPKDGFSPRRRGVAEGPGAELSLCYQKALLSHRPREVTVSL 610
D ED+ +EL K+Q S P++ + V E E ++ Y SH P +
Sbjct: 189 DDDEDV-QVELAEKVQKSSAPREMQKAEEKEVPEDSQEECAITYSN---SHGPYDSNQPH 244
Query: 611 RATGLILKAIPASDTEVSGSSH 632
R T + + T + SSH
Sbjct: 245 RKTKITFEEDKVDSTLIGSSSH 266
>gi|156151427 OPA3 protein isoform a [Homo sapiens]
Length = 180
Score = 30.4 bits (67), Expect = 6.3
Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 9/82 (10%)
Query: 163 LVSASVCSALLLEIEAAQAQQTPETCMRHVVSHALQAALGEACHAGALHRKLQASPRRTL 222
++ + CS L+LE Q QQ + R V AL+ GE H G +LQA + T
Sbjct: 88 IIFITACSCLMLEYWRHQLQQRRKEKERRVAREALR---GEVGHLGLALEELQAQVQAT- 143
Query: 223 EHYFHAVVAALEQMASEASPSR 244
+ ALE++ ++ R
Sbjct: 144 -----STQLALEELRAQLQEVR 160
>gi|21704281 junctophilin 2 isoform 1 [Homo sapiens]
Length = 696
Score = 30.4 bits (67), Expect = 6.3
Identities = 50/209 (23%), Positives = 73/209 (34%), Gaps = 38/209 (18%)
Query: 212 RKLQASPRRTLEHYFHAV-----VAALEQMASEASPSREGHVERLEEI--YCSLLGPAAG 264
R LQ + + H+V AA+ + +E + SR H + E +L
Sbjct: 353 RMLQLKSNKVRQKVEHSVEGAQRAAAIARQKAEIAASRTSHAKAKAEAAEQAALAANQES 412
Query: 265 RCGGDLVQERPPSIPLPSPYITFHLWTGEEQLWKELVLFLRPRSQLRLSADLEVLDLQGL 324
L +E P P P E + L+ + S+ L GL
Sbjct: 413 NIARTLARELAPDFYQPGP----------EYQKRRLLQEILENSESLLEPPDRGAGAAGL 462
Query: 325 -RPDRELARVSVLSTDSGIERDLPTGADELPA--PGSPEMERAGLQRKGGIKKRAWPLDF 381
+P RE ++ T P G PA P P+ R G+ + G
Sbjct: 463 PQPPRESPQLHERETPR------PEGGSPSPAGTPPQPKRPRPGVSKDG----------L 506
Query: 382 LMPGSWDG-PPGLHRRTGRPS-GDGEMLP 408
L PG+W+G P G R+ PS G G P
Sbjct: 507 LSPGAWNGEPSGEGSRSVTPSEGAGRRSP 535
>gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens]
Length = 1505
Score = 30.0 bits (66), Expect = 8.3
Identities = 28/111 (25%), Positives = 47/111 (42%), Gaps = 18/111 (16%)
Query: 19 RELSTQAPALQSNQGMWRWSLHKKVERDPGKSPVLVRILLRELEKAESQDLRHVIIPLLH 78
REL A L + Q S + +E+ RE +K +DLR + PLL
Sbjct: 11 RELDATATVLANRQDESEQSRKRLIEQS------------REFKKNTPEDLRKQVAPLLK 58
Query: 79 TV---MYVLTKATGITEELYQRIYAFCTRLLTLPTPYCTVALDCAIRLKTE 126
+ + L+K + E + +Y RL+ +P P + L ++LK +
Sbjct: 59 SFQGEIDALSKRSKEAEAAFLNVY---KRLIDVPDPVPALDLGQQLQLKVQ 106
>gi|23111032 sorting nexin 1 isoform b [Homo sapiens]
Length = 457
Score = 30.0 bits (66), Expect = 8.3
Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 5 DVELDLQRSVQAVLRELSTQAP--ALQSNQGMWRW-SLHKKVERDPGKSPVLVRILLREL 61
D + LQ+ +A R L P Q+ + W S + ERD + +VR +
Sbjct: 357 DAQATLQKKREAEARLLWANKPDKLQQAKDEILEWESRVTQYERDFERISTVVRKEVIRF 416
Query: 62 EKAESQDLRHVIIPLLHTVMY 82
EK +S+D ++ +I L T++Y
Sbjct: 417 EKEKSKDFKNHVIKYLETLLY 437
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,626,134
Number of Sequences: 37866
Number of extensions: 1502239
Number of successful extensions: 4221
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 4134
Number of HSP's gapped (non-prelim): 115
length of query: 754
length of database: 18,247,518
effective HSP length: 110
effective length of query: 644
effective length of database: 14,082,258
effective search space: 9068974152
effective search space used: 9068974152
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.