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Search of human proteins with 5730120
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5730120 YKT6 v-SNARE protein [Homo sapiens]
(198 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5730120 YKT6 v-SNARE protein [Homo sapiens] 390 e-109
gi|5032137 vesicle-associated membrane protein 7 isoform 1 [Homo... 57 1e-08
gi|94429050 SEC22 vesicle trafficking protein homolog B [Homo sa... 44 7e-05
gi|223468574 vesicle-associated membrane protein 7 isoform 2 [Ho... 40 0.002
gi|42544207 vesicle-associated membrane protein 4 [Homo sapiens] 39 0.002
gi|14043026 vesicle-associated membrane protein 8 [Homo sapiens] 37 0.014
gi|46049063 exportin 6 [Homo sapiens] 34 0.093
gi|172072620 vesicle-associated membrane protein 2 (synaptobrevi... 32 0.35
gi|40549446 vesicle-associated membrane protein 1 isoform 2 [Hom... 31 0.79
gi|7657673 vesicle-associated membrane protein 1 isoform 1 [Homo... 31 0.79
gi|9257251 vesicle-associated membrane protein 1 isoform 3 [Homo... 31 0.79
gi|213688415 coiled-coil domain containing 66 isoform 1 [Homo sa... 30 1.0
gi|213688413 coiled-coil domain containing 66 isoform 2 [Homo sa... 30 1.0
gi|4759300 vesicle-associated membrane protein 3 [Homo sapiens] 30 1.8
gi|193788653 hypothetical protein LOC100131897 [Homo sapiens] 29 2.3
gi|13775200 SF3b10 [Homo sapiens] 29 2.3
gi|57863263 testis expressed sequence 14 isoform a [Homo sapiens] 28 3.9
gi|57863261 testis expressed sequence 14 isoform b [Homo sapiens] 28 3.9
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa... 28 6.7
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap... 28 6.7
gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens] 28 6.7
gi|54792073 mucolipin 2 [Homo sapiens] 28 6.7
>gi|5730120 YKT6 v-SNARE protein [Homo sapiens]
Length = 198
Score = 390 bits (1002), Expect = e-109
Identities = 198/198 (100%), Positives = 198/198 (100%)
Query: 1 MKLYSLSVLYKGEAKVVLLKAAYDVSSFSFFQRSSVQEFMTFTSQLIVERSSKGTRASVK 60
MKLYSLSVLYKGEAKVVLLKAAYDVSSFSFFQRSSVQEFMTFTSQLIVERSSKGTRASVK
Sbjct: 1 MKLYSLSVLYKGEAKVVLLKAAYDVSSFSFFQRSSVQEFMTFTSQLIVERSSKGTRASVK 60
Query: 61 EQDYLCHVYVRNDSLAGVVIADNEYPSRVAFTLLEKVLDEFSKQVDRIDWPVGSPATIHY 120
EQDYLCHVYVRNDSLAGVVIADNEYPSRVAFTLLEKVLDEFSKQVDRIDWPVGSPATIHY
Sbjct: 61 EQDYLCHVYVRNDSLAGVVIADNEYPSRVAFTLLEKVLDEFSKQVDRIDWPVGSPATIHY 120
Query: 121 PALDGHLSRYQNPREADPMTKVQAELDETKIILHNTMESLLERGEKLDDLVSKSEVLGTQ 180
PALDGHLSRYQNPREADPMTKVQAELDETKIILHNTMESLLERGEKLDDLVSKSEVLGTQ
Sbjct: 121 PALDGHLSRYQNPREADPMTKVQAELDETKIILHNTMESLLERGEKLDDLVSKSEVLGTQ 180
Query: 181 SKAFYKTARKQNSCCAIM 198
SKAFYKTARKQNSCCAIM
Sbjct: 181 SKAFYKTARKQNSCCAIM 198
>gi|5032137 vesicle-associated membrane protein 7 isoform 1 [Homo
sapiens]
Length = 220
Score = 56.6 bits (135), Expect = 1e-08
Identities = 38/156 (24%), Positives = 75/156 (48%), Gaps = 9/156 (5%)
Query: 39 FMTFTSQLIVERSSKGTRASVKEQDYLCHVYVRNDSLAGVVIADNEYPSRVAFTLLEKVL 98
F+ T Q++ + S+ + + +YL H Y+ D + + I D+++ AF L ++
Sbjct: 25 FLEVTEQILAKIPSENNKLTYSHGNYLFH-YICQDRIVYLCITDDDFERSRAFNFLNEIK 83
Query: 99 DEF-----SKQVDRIDWPVGSPATIHYPALDGHLSRYQNPREADPMTKVQAELDETKIIL 153
F S+ + + + S + L L + + D + + QA++DE K I+
Sbjct: 84 KRFQTTYGSRAQTALPYAMNSEFS---SVLAAQLKHHSENKGLDKVMETQAQVDELKGIM 140
Query: 154 HNTMESLLERGEKLDDLVSKSEVLGTQSKAFYKTAR 189
++ + +RGE+L+ L+ K+E L S F T+R
Sbjct: 141 VRNIDLVAQRGERLELLIDKTENLVDSSVTFKTTSR 176
>gi|94429050 SEC22 vesicle trafficking protein homolog B [Homo
sapiens]
Length = 215
Score = 44.3 bits (103), Expect = 7e-05
Identities = 35/161 (21%), Positives = 71/161 (44%), Gaps = 6/161 (3%)
Query: 36 VQEFMTFTSQLIVERSSKGTRASVKEQDYLCHVYVRNDSLAGVVIADNEYPSRVAFTLLE 95
+Q++ + QL + + + E + Y+ + +V+ + +P +AF LE
Sbjct: 30 LQQYQSQAKQLFRKLNEQSPTRCTLEAGAMTFHYIIEQGVCDLVLCEAAFPKTLAFAYLE 89
Query: 96 KVLDEFSKQVDRIDWPVGSPATIHYPALDGHLSR----YQNPREADPMTKVQAELDETKI 151
+ EF +Q + V P + + D + + Y + + + EL + +
Sbjct: 90 DLHSEFDEQHGKKVPTVSRPYS--FIEFDTFIQKTKKLYIDSCARRNLGSINTELQDVQR 147
Query: 152 ILHNTMESLLERGEKLDDLVSKSEVLGTQSKAFYKTARKQN 192
I+ +E +L+RGE L L SK+ L + SK + + A+ N
Sbjct: 148 IMVANIEEVLQRGEALSALDSKANNLSSLSKKYRQDAKYLN 188
>gi|223468574 vesicle-associated membrane protein 7 isoform 2 [Homo
sapiens]
Length = 179
Score = 39.7 bits (91), Expect = 0.002
Identities = 21/67 (31%), Positives = 37/67 (55%)
Query: 123 LDGHLSRYQNPREADPMTKVQAELDETKIILHNTMESLLERGEKLDDLVSKSEVLGTQSK 182
L L + + D + + QA++DE K I+ ++ + +RGE+L+ L+ K+E L S
Sbjct: 69 LAAQLKHHSENKGLDKVMETQAQVDELKGIMVRNIDLVAQRGERLELLIDKTENLVDSSV 128
Query: 183 AFYKTAR 189
F T+R
Sbjct: 129 TFKTTSR 135
>gi|42544207 vesicle-associated membrane protein 4 [Homo sapiens]
Length = 141
Score = 39.3 bits (90), Expect = 0.002
Identities = 18/54 (33%), Positives = 32/54 (59%)
Query: 137 DPMTKVQAELDETKIILHNTMESLLERGEKLDDLVSKSEVLGTQSKAFYKTARK 190
D + VQ ++DE ++ + ++ERGE+LD+L KSE L + AF +++
Sbjct: 51 DKIKHVQNQVDEVIDVMQENITKVIERGERLDELQDKSESLSDNATAFSNRSKQ 104
>gi|14043026 vesicle-associated membrane protein 8 [Homo sapiens]
Length = 100
Score = 36.6 bits (83), Expect = 0.014
Identities = 19/54 (35%), Positives = 33/54 (61%)
Query: 137 DPMTKVQAELDETKIILHNTMESLLERGEKLDDLVSKSEVLGTQSKAFYKTARK 190
D + +Q+E++ K I+ +E +L RGE L+ L +K+E L S+ F T++K
Sbjct: 11 DRVRNLQSEVEGVKNIMTQNVERILARGENLEHLRNKTEDLEATSEHFKTTSQK 64
>gi|46049063 exportin 6 [Homo sapiens]
Length = 1125
Score = 33.9 bits (76), Expect = 0.093
Identities = 24/73 (32%), Positives = 40/73 (54%), Gaps = 4/73 (5%)
Query: 110 WPVGSPATIHYPALDGHLSR-YQNPREADPMTKVQAELDETKIILHNTMESLLERGEKLD 168
WPV S I++ +L LSR Y+N + + + + LD+TK+I+H T+ L + E +
Sbjct: 744 WPVRS---INHASLISALSRDYRNLKPSAVAPQRKMPLDDTKLIIHQTLSVLEDIVENIS 800
Query: 169 DLVSKSEVLGTQS 181
+KS + QS
Sbjct: 801 GESTKSRQICYQS 813
>gi|172072620 vesicle-associated membrane protein 2 (synaptobrevin
2) [Homo sapiens]
Length = 116
Score = 32.0 bits (71), Expect = 0.35
Identities = 15/52 (28%), Positives = 30/52 (57%)
Query: 139 MTKVQAELDETKIILHNTMESLLERGEKLDDLVSKSEVLGTQSKAFYKTARK 190
+ + QA++DE I+ ++ +LER +KL +L +++ L + F +A K
Sbjct: 32 LQQTQAQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAK 83
>gi|40549446 vesicle-associated membrane protein 1 isoform 2 [Homo
sapiens]
Length = 117
Score = 30.8 bits (68), Expect = 0.79
Identities = 14/52 (26%), Positives = 30/52 (57%)
Query: 139 MTKVQAELDETKIILHNTMESLLERGEKLDDLVSKSEVLGTQSKAFYKTARK 190
+ + QA+++E I+ ++ +LER +KL +L +++ L + F +A K
Sbjct: 34 LQQTQAQVEEVVDIIRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAK 85
>gi|7657673 vesicle-associated membrane protein 1 isoform 1 [Homo
sapiens]
Length = 118
Score = 30.8 bits (68), Expect = 0.79
Identities = 14/52 (26%), Positives = 30/52 (57%)
Query: 139 MTKVQAELDETKIILHNTMESLLERGEKLDDLVSKSEVLGTQSKAFYKTARK 190
+ + QA+++E I+ ++ +LER +KL +L +++ L + F +A K
Sbjct: 34 LQQTQAQVEEVVDIIRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAK 85
>gi|9257251 vesicle-associated membrane protein 1 isoform 3 [Homo
sapiens]
Length = 116
Score = 30.8 bits (68), Expect = 0.79
Identities = 14/52 (26%), Positives = 30/52 (57%)
Query: 139 MTKVQAELDETKIILHNTMESLLERGEKLDDLVSKSEVLGTQSKAFYKTARK 190
+ + QA+++E I+ ++ +LER +KL +L +++ L + F +A K
Sbjct: 34 LQQTQAQVEEVVDIIRVNVDKVLERDQKLSELDDRADALQAGASQFESSAAK 85
>gi|213688415 coiled-coil domain containing 66 isoform 1 [Homo
sapiens]
Length = 948
Score = 30.4 bits (67), Expect = 1.0
Identities = 23/101 (22%), Positives = 42/101 (41%), Gaps = 4/101 (3%)
Query: 91 FTLLEKVLDEFSKQVDRIDWPVGSPATIHYPALDGHLSRYQNPREADPMTKVQAELDETK 150
FT +EK K R DW + P + PA + + + Q RE KV+ +++
Sbjct: 684 FTRIEKQTKHMKKYPKRPDWNINKPPKRYIPASEKYPKQLQKQREE---KKVRRQMELLH 740
Query: 151 IILHNTMESLLERGEKLDDLVSKSEVLGTQSKAFYKTARKQ 191
++ N L + + + S T+SK + +K+
Sbjct: 741 LVEKNN-PGHLSQNRGISPEIFHSSHQETESKLRWHLVKKE 780
>gi|213688413 coiled-coil domain containing 66 isoform 2 [Homo
sapiens]
Length = 914
Score = 30.4 bits (67), Expect = 1.0
Identities = 23/101 (22%), Positives = 42/101 (41%), Gaps = 4/101 (3%)
Query: 91 FTLLEKVLDEFSKQVDRIDWPVGSPATIHYPALDGHLSRYQNPREADPMTKVQAELDETK 150
FT +EK K R DW + P + PA + + + Q RE KV+ +++
Sbjct: 650 FTRIEKQTKHMKKYPKRPDWNINKPPKRYIPASEKYPKQLQKQREE---KKVRRQMELLH 706
Query: 151 IILHNTMESLLERGEKLDDLVSKSEVLGTQSKAFYKTARKQ 191
++ N L + + + S T+SK + +K+
Sbjct: 707 LVEKNN-PGHLSQNRGISPEIFHSSHQETESKLRWHLVKKE 746
>gi|4759300 vesicle-associated membrane protein 3 [Homo sapiens]
Length = 100
Score = 29.6 bits (65), Expect = 1.8
Identities = 14/52 (26%), Positives = 29/52 (55%)
Query: 139 MTKVQAELDETKIILHNTMESLLERGEKLDDLVSKSEVLGTQSKAFYKTARK 190
+ + Q ++DE I+ ++ +LER +KL +L +++ L + F +A K
Sbjct: 15 LQQTQNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAK 66
>gi|193788653 hypothetical protein LOC100131897 [Homo sapiens]
Length = 535
Score = 29.3 bits (64), Expect = 2.3
Identities = 25/98 (25%), Positives = 49/98 (50%), Gaps = 10/98 (10%)
Query: 106 DRIDWPVGSPATIHYPA-LDGHLSRYQNPREADPMTKV---QAELDETKIILHNTMESLL 161
D +++P P + H P+ L ++ Q+ RE + ++ + EL + + L + ESL
Sbjct: 366 DTLEFP-NCPGSNHLPSSLSRSETKLQSNREISDINQIHLARGELCDLQGRLQSVEESLH 424
Query: 162 ERGEKLDDLVSKSEVLG-----TQSKAFYKTARKQNSC 194
EK+ L++ + L T+ + FY+T + N+C
Sbjct: 425 SNQEKIKVLLNVIQDLEKARALTEGRNFYRTGQDLNNC 462
>gi|13775200 SF3b10 [Homo sapiens]
Length = 86
Score = 29.3 bits (64), Expect = 2.3
Identities = 16/48 (33%), Positives = 23/48 (47%)
Query: 60 KEQDYLCHVYVRNDSLAGVVIADNEYPSRVAFTLLEKVLDEFSKQVDR 107
+ +D C D L IA+NE +RV F L+EK+L D+
Sbjct: 35 QHRDSYCSYMGHFDLLNYFAIAENESKARVRFNLMEKMLQPCGPPADK 82
>gi|57863263 testis expressed sequence 14 isoform a [Homo sapiens]
Length = 1491
Score = 28.5 bits (62), Expect = 3.9
Identities = 28/96 (29%), Positives = 48/96 (50%), Gaps = 14/96 (14%)
Query: 3 LYSLSVLYKGEAKVVLLKAAYDVSSFSFFQRSSVQEFMTFTSQLIVERSSKGTRASVKEQ 62
L SL V+ GE +V+ A D +FSFF +M T+ + G+R +VKE
Sbjct: 224 LGSLPVI--GEKEVI---QADDEPTFSFFSGP----YMVMTNLVW-----NGSRVTVKEL 269
Query: 63 DYLCHVYVRNDSLAGVVIADNEYPSRVAFTLLEKVL 98
+ H + LA ++IA+ E+ S++ L +++
Sbjct: 270 NLPTHPHCSRLRLADLLIAEQEHSSKLRHPYLLQLM 305
>gi|57863261 testis expressed sequence 14 isoform b [Homo sapiens]
Length = 1451
Score = 28.5 bits (62), Expect = 3.9
Identities = 28/96 (29%), Positives = 48/96 (50%), Gaps = 14/96 (14%)
Query: 3 LYSLSVLYKGEAKVVLLKAAYDVSSFSFFQRSSVQEFMTFTSQLIVERSSKGTRASVKEQ 62
L SL V+ GE +V+ A D +FSFF +M T+ + G+R +VKE
Sbjct: 224 LGSLPVI--GEKEVI---QADDEPTFSFFSGP----YMVMTNLVW-----NGSRVTVKEL 269
Query: 63 DYLCHVYVRNDSLAGVVIADNEYPSRVAFTLLEKVL 98
+ H + LA ++IA+ E+ S++ L +++
Sbjct: 270 NLPTHPHCSRLRLADLLIAEQEHSSKLRHPYLLQLM 305
>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
sapiens]
Length = 521
Score = 27.7 bits (60), Expect = 6.7
Identities = 16/38 (42%), Positives = 20/38 (52%), Gaps = 4/38 (10%)
Query: 111 PVGSPATIHYPALDGHLSRYQNPREADPMTKVQAELDE 148
PV +P +IH + DG +P P KV AELDE
Sbjct: 77 PVPAPRSIHKSSQDGDTPAQASP----PEEKVPAELDE 110
>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo
sapiens]
Length = 548
Score = 27.7 bits (60), Expect = 6.7
Identities = 16/38 (42%), Positives = 20/38 (52%), Gaps = 4/38 (10%)
Query: 111 PVGSPATIHYPALDGHLSRYQNPREADPMTKVQAELDE 148
PV +P +IH + DG +P P KV AELDE
Sbjct: 104 PVPAPRSIHKSSQDGDTPAQASP----PEEKVPAELDE 137
>gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]
Length = 495
Score = 27.7 bits (60), Expect = 6.7
Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 7/67 (10%)
Query: 131 QNPREADPMTKVQAELDETKIILHNT----MESLLERGEKLDDLVSKSEVLGTQSKAFYK 186
Q RE D M KVQ E +E ++ L N +E +L + E L+ + + E+ + YK
Sbjct: 277 QQQREEDRMAKVQ-ENEEKRLQLQNALTQKLEEMLRQREDLEQV--RQELYQEEQAEIYK 333
Query: 187 TARKQNS 193
+ K+ +
Sbjct: 334 SKLKEEA 340
>gi|54792073 mucolipin 2 [Homo sapiens]
Length = 566
Score = 27.7 bits (60), Expect = 6.7
Identities = 12/33 (36%), Positives = 16/33 (48%)
Query: 61 EQDYLCHVYVRNDSLAGVVIADNEYPSRVAFTL 93
E DY C VY + D+ + A N+Y TL
Sbjct: 114 EDDYSCSVYTQEDAYESIFFAINQYHQLKDITL 146
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.131 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,096,854
Number of Sequences: 37866
Number of extensions: 234719
Number of successful extensions: 741
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 725
Number of HSP's gapped (non-prelim): 22
length of query: 198
length of database: 18,247,518
effective HSP length: 97
effective length of query: 101
effective length of database: 14,574,516
effective search space: 1472026116
effective search space used: 1472026116
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.