Guide to the Human Genome
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Search of human proteins with 5730059

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5730059 fibroblast growth factor receptor substrate 3 [Homo
sapiens]
         (492 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5730059 fibroblast growth factor receptor substrate 3 [Homo s...  1042   0.0  
gi|110347414 fibroblast growth factor receptor substrate 2 [Homo...   441   e-124
gi|110347408 fibroblast growth factor receptor substrate 2 [Homo...   441   e-124
gi|4503357 docking protein 1 [Homo sapiens]                            62   2e-09
gi|47575849 docking protein 6 [Homo sapiens]                           60   6e-09
gi|221554537 docking protein 3 isoform 1 [Homo sapiens]                59   1e-08
gi|41406050 docking protein 2 [Homo sapiens]                           58   2e-08
gi|20070302 docking protein 4 [Homo sapiens]                           56   9e-08
gi|29544726 docking protein 5 [Homo sapiens]                           54   2e-07
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    47   4e-05
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    40   0.004
gi|111185957 downstream of tyrosine kinase 7 [Homo sapiens]            40   0.006
gi|149944516 tet oncogene family member 3 [Homo sapiens]               38   0.024
gi|56117844 synovial sarcoma translocation, chromosome 18 isofor...    37   0.053
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    37   0.053
gi|153792074 proline rich 12 [Homo sapiens]                            35   0.12 
gi|237757326 synaptojanin 1 isoform d [Homo sapiens]                   35   0.16 
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    35   0.20 
gi|150170670 piccolo isoform 2 [Homo sapiens]                          34   0.35 
gi|150378539 piccolo isoform 1 [Homo sapiens]                          34   0.35 
gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo ...    33   0.45 
gi|239743279 PREDICTED: hypothetical protein XP_002342816 [Homo ...    33   0.45 
gi|239508962 PREDICTED: hypothetical protein [Homo sapiens]            33   0.45 
gi|95147555 microtubule-associated protein 1A [Homo sapiens]           33   0.59 
gi|237757310 synaptojanin 1 isoform a [Homo sapiens]                   33   0.77 
gi|222352183 neural precursor cell expressed, developmentally do...    33   0.77 
gi|21361472 neural precursor cell expressed, developmentally dow...    33   0.77 
gi|222352094 neural precursor cell expressed, developmentally do...    33   0.77 
gi|222352092 neural precursor cell expressed, developmentally do...    33   0.77 
gi|222352090 neural precursor cell expressed, developmentally do...    33   0.77 

>gi|5730059 fibroblast growth factor receptor substrate 3 [Homo
           sapiens]
          Length = 492

 Score = 1042 bits (2694), Expect = 0.0
 Identities = 492/492 (100%), Positives = 492/492 (100%)

Query: 1   MGSCCSCLNRDSVPDNHPTKFKVTNVDDEGVELGSGVMELTQSELVLHLHRREAVRWPYL 60
           MGSCCSCLNRDSVPDNHPTKFKVTNVDDEGVELGSGVMELTQSELVLHLHRREAVRWPYL
Sbjct: 1   MGSCCSCLNRDSVPDNHPTKFKVTNVDDEGVELGSGVMELTQSELVLHLHRREAVRWPYL 60

Query: 61  CLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQDLMQCNSINVMEEPVIIT 120
           CLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQDLMQCNSINVMEEPVIIT
Sbjct: 61  CLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQDLMQCNSINVMEEPVIIT 120

Query: 121 RNSHPAELDLPRAPQPPNALGYTVSSFSNGCPGEGPRFSAPRRLSTSSLRHPSLGEESTH 180
           RNSHPAELDLPRAPQPPNALGYTVSSFSNGCPGEGPRFSAPRRLSTSSLRHPSLGEESTH
Sbjct: 121 RNSHPAELDLPRAPQPPNALGYTVSSFSNGCPGEGPRFSAPRRLSTSSLRHPSLGEESTH 180

Query: 181 ALIAPDEQSHTYVNTPASEDDHRRGRHCLQPLPEGQAPFLPQARGPDQRDPQVFLQPGQV 240
           ALIAPDEQSHTYVNTPASEDDHRRGRHCLQPLPEGQAPFLPQARGPDQRDPQVFLQPGQV
Sbjct: 181 ALIAPDEQSHTYVNTPASEDDHRRGRHCLQPLPEGQAPFLPQARGPDQRDPQVFLQPGQV 240

Query: 241 KFVLGPTPARRHMVKCQGLCPSLHDPPHHNNNNEAPSECPAQPKCTYENVTGGLWRGAGW 300
           KFVLGPTPARRHMVKCQGLCPSLHDPPHHNNNNEAPSECPAQPKCTYENVTGGLWRGAGW
Sbjct: 241 KFVLGPTPARRHMVKCQGLCPSLHDPPHHNNNNEAPSECPAQPKCTYENVTGGLWRGAGW 300

Query: 301 RLSPEEPGWNGLAHRRAALLHYENLPPLPPVWESQAQQLGGEAGDDGDSRDGLTPSSNGF 360
           RLSPEEPGWNGLAHRRAALLHYENLPPLPPVWESQAQQLGGEAGDDGDSRDGLTPSSNGF
Sbjct: 301 RLSPEEPGWNGLAHRRAALLHYENLPPLPPVWESQAQQLGGEAGDDGDSRDGLTPSSNGF 360

Query: 361 PDGEEDETPLQKPTSTRAAIRSHGSFPVPLTRRRGSPRVFNFDFRRPGPEPPRQLNYIQV 420
           PDGEEDETPLQKPTSTRAAIRSHGSFPVPLTRRRGSPRVFNFDFRRPGPEPPRQLNYIQV
Sbjct: 361 PDGEEDETPLQKPTSTRAAIRSHGSFPVPLTRRRGSPRVFNFDFRRPGPEPPRQLNYIQV 420

Query: 421 ELKGWGGDRPKGPQNPSSPQAPMPTTHPARSSDSYAVIDLKKTVAMSNLQRALPRDDGTA 480
           ELKGWGGDRPKGPQNPSSPQAPMPTTHPARSSDSYAVIDLKKTVAMSNLQRALPRDDGTA
Sbjct: 421 ELKGWGGDRPKGPQNPSSPQAPMPTTHPARSSDSYAVIDLKKTVAMSNLQRALPRDDGTA 480

Query: 481 RKTRHNSTDLPL 492
           RKTRHNSTDLPL
Sbjct: 481 RKTRHNSTDLPL 492


>gi|110347414 fibroblast growth factor receptor substrate 2 [Homo
           sapiens]
          Length = 508

 Score =  441 bits (1133), Expect = e-124
 Identities = 249/522 (47%), Positives = 327/522 (62%), Gaps = 44/522 (8%)

Query: 1   MGSCCSCLNRDSVPDNHPTKFKVTNVDDEGVELGSGVMELTQSELVLHLHRREAVRWPYL 60
           MGSCCSC ++D+VPDNH  KFKV NVDD+G ELGSG+MELT +EL+L+  +R++V+W YL
Sbjct: 1   MGSCCSCPDKDTVPDNHRNKFKVINVDDDGNELGSGIMELTDTELILYTRKRDSVKWHYL 60

Query: 61  CLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQDLMQCNSINVMEEPVIIT 120
           CLRRYGYDSNLFSFESGRRCQTGQGIFAFKC+RAEE+FN+LQ++MQ NSINV+EEPV + 
Sbjct: 61  CLRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIMQNNSINVVEEPV-VE 119

Query: 121 RNSHPAELDLPRAPQPPNALGYTVSSFSNGCP-----GEGPRFSAPRRLSTSSLRHPSLG 175
           RN+H  EL++PR P+ P   G+   +  NG P     G+     + R  S  S R PS+G
Sbjct: 120 RNNHQTELEVPRTPRTPTTPGFAAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVG 179

Query: 176 EESTHALIAPDEQSHTYVNTPASEDDHRRGRHCLQPL------PEGQAPFLPQARGPDQR 229
           EESTH L+  +EQ HTYVNT   +++ +       PL       E   P   +    + R
Sbjct: 180 EESTHPLLVAEEQVHTYVNTTGVQEERKNRTSVHVPLEARVSNAESSTP-KEEPSSIEDR 238

Query: 230 DPQVFLQPGQVKFVLGPTPARRHMVKCQGLCPSLHDPPHHN--NNNEAPS--------EC 279
           DPQ+ L+P  VKFVLGPTP ++ +++ + L     D    +  NN E  +        + 
Sbjct: 239 DPQILLEPEGVKFVLGPTPVQKQLMEKEKLEQLGRDQVSGSGANNTEWDTGYDSDERRDA 298

Query: 280 PAQPKCTYENVTG-------GLWRGAGWRLSPEE-PGWNGLAHRRAALLHYENLPPLPPV 331
           P+  K  YEN+ G       G+ RG     S  +    N  A RR ALL+YENLP LPPV
Sbjct: 299 PSVNKLVYENINGLSIPSASGVRRGRLTSTSTSDTQNINNSAQRRTALLNYENLPSLPPV 358

Query: 332 WESQAQQLGGEAGDDGDSRDGLTPSSNGFPDGEEDETPLQKPTSTRAAIRSHGSFPVPLT 391
           WE++       + D+ D+    TPS NG+ +  +   P+    +T        +  +  +
Sbjct: 359 WEARKL-----SRDEDDNLGPKTPSLNGYHNNLD---PMHNYVNTENVTVPASAHKIEYS 410

Query: 392 RRRG-SPRVFNFDFRRPGPEPPRQLNYIQVELKGWGGDRPKGPQNPSSPQAPMPTTHPAR 450
           RRR  +P VFNFD RRP  E  RQLNYIQV+L+  GG     PQ P +P  P+P T P R
Sbjct: 411 RRRDCTPTVFNFDIRRPSLE-HRQLNYIQVDLE--GGSDSDNPQTPKTPTTPLPQT-PTR 466

Query: 451 SSDSYAVIDLKKTVAMSNLQRALPRDDGTARKTRHNSTDLPL 492
            ++ YAVID+++T AMSNLQ+ALPRDDGT+RKTRHNSTDLP+
Sbjct: 467 RTELYAVIDIERTAAMSNLQKALPRDDGTSRKTRHNSTDLPM 508


>gi|110347408 fibroblast growth factor receptor substrate 2 [Homo
           sapiens]
          Length = 508

 Score =  441 bits (1133), Expect = e-124
 Identities = 249/522 (47%), Positives = 327/522 (62%), Gaps = 44/522 (8%)

Query: 1   MGSCCSCLNRDSVPDNHPTKFKVTNVDDEGVELGSGVMELTQSELVLHLHRREAVRWPYL 60
           MGSCCSC ++D+VPDNH  KFKV NVDD+G ELGSG+MELT +EL+L+  +R++V+W YL
Sbjct: 1   MGSCCSCPDKDTVPDNHRNKFKVINVDDDGNELGSGIMELTDTELILYTRKRDSVKWHYL 60

Query: 61  CLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQDLMQCNSINVMEEPVIIT 120
           CLRRYGYDSNLFSFESGRRCQTGQGIFAFKC+RAEE+FN+LQ++MQ NSINV+EEPV + 
Sbjct: 61  CLRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIMQNNSINVVEEPV-VE 119

Query: 121 RNSHPAELDLPRAPQPPNALGYTVSSFSNGCP-----GEGPRFSAPRRLSTSSLRHPSLG 175
           RN+H  EL++PR P+ P   G+   +  NG P     G+     + R  S  S R PS+G
Sbjct: 120 RNNHQTELEVPRTPRTPTTPGFAAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVG 179

Query: 176 EESTHALIAPDEQSHTYVNTPASEDDHRRGRHCLQPL------PEGQAPFLPQARGPDQR 229
           EESTH L+  +EQ HTYVNT   +++ +       PL       E   P   +    + R
Sbjct: 180 EESTHPLLVAEEQVHTYVNTTGVQEERKNRTSVHVPLEARVSNAESSTP-KEEPSSIEDR 238

Query: 230 DPQVFLQPGQVKFVLGPTPARRHMVKCQGLCPSLHDPPHHN--NNNEAPS--------EC 279
           DPQ+ L+P  VKFVLGPTP ++ +++ + L     D    +  NN E  +        + 
Sbjct: 239 DPQILLEPEGVKFVLGPTPVQKQLMEKEKLEQLGRDQVSGSGANNTEWDTGYDSDERRDA 298

Query: 280 PAQPKCTYENVTG-------GLWRGAGWRLSPEE-PGWNGLAHRRAALLHYENLPPLPPV 331
           P+  K  YEN+ G       G+ RG     S  +    N  A RR ALL+YENLP LPPV
Sbjct: 299 PSVNKLVYENINGLSIPSASGVRRGRLTSTSTSDTQNINNSAQRRTALLNYENLPSLPPV 358

Query: 332 WESQAQQLGGEAGDDGDSRDGLTPSSNGFPDGEEDETPLQKPTSTRAAIRSHGSFPVPLT 391
           WE++       + D+ D+    TPS NG+ +  +   P+    +T        +  +  +
Sbjct: 359 WEARKL-----SRDEDDNLGPKTPSLNGYHNNLD---PMHNYVNTENVTVPASAHKIEYS 410

Query: 392 RRRG-SPRVFNFDFRRPGPEPPRQLNYIQVELKGWGGDRPKGPQNPSSPQAPMPTTHPAR 450
           RRR  +P VFNFD RRP  E  RQLNYIQV+L+  GG     PQ P +P  P+P T P R
Sbjct: 411 RRRDCTPTVFNFDIRRPSLE-HRQLNYIQVDLE--GGSDSDNPQTPKTPTTPLPQT-PTR 466

Query: 451 SSDSYAVIDLKKTVAMSNLQRALPRDDGTARKTRHNSTDLPL 492
            ++ YAVID+++T AMSNLQ+ALPRDDGT+RKTRHNSTDLP+
Sbjct: 467 RTELYAVIDIERTAAMSNLQKALPRDDGTSRKTRHNSTDLPM 508


>gi|4503357 docking protein 1 [Homo sapiens]
          Length = 481

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 30/83 (36%), Positives = 46/83 (55%), Gaps = 2/83 (2%)

Query: 57  WPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQDLM--QCNSINVME 114
           WPY  LRRYG D  +FSFE+GRRC +G G F F+ ++  +IF  ++  +  Q       +
Sbjct: 201 WPYTLLRRYGRDKVMFSFEAGRRCPSGPGTFTFQTAQGNDIFQAVETAIHRQKAQGKAGQ 260

Query: 115 EPVIITRNSHPAELDLPRAPQPP 137
              ++  +SH  E+   + P PP
Sbjct: 261 GHDVLRADSHEGEVAEGKLPSPP 283


>gi|47575849 docking protein 6 [Homo sapiens]
          Length = 331

 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 29/68 (42%), Positives = 39/68 (57%), Gaps = 3/68 (4%)

Query: 34  GSGVMELTQSELVL---HLHRREAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFK 90
           G   M++T   + L   H  + + V WP   LRRYG DS  F+FESGR C TG+G+F F+
Sbjct: 153 GECTMQITHENIYLWDIHNAKVKLVMWPLSSLRRYGRDSTWFTFESGRMCDTGEGLFTFQ 212

Query: 91  CSRAEEIF 98
               E I+
Sbjct: 213 TREGEMIY 220


>gi|221554537 docking protein 3 isoform 1 [Homo sapiens]
          Length = 496

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 63/232 (27%), Positives = 84/232 (36%), Gaps = 68/232 (29%)

Query: 57  WPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQDLMQCNSINVMEEP 116
           WPY  LR++G D  +FSFE+GRRC +G+G+FAF    A ++         C ++      
Sbjct: 259 WPYHFLRKFGSDKGVFSFEAGRRCHSGEGLFAFSTPCAPDL---------CRAV----AG 305

Query: 117 VIITRNSHPAELDLPRAPQPPNALGYTVSSFSNGCPGEGPRFSAPRRLSTSSLRHPSLGE 176
            I  +     EL     PQP              CP        PR  S  SL  P    
Sbjct: 306 AIARQRERLPEL---TRPQP--------------CP-------LPRATSLPSLDTPGELR 341

Query: 177 ESTHALIAPDEQSHTYVNTPASEDDHRRGRHCLQPLPEGQAPFLPQARGPDQRDPQVFLQ 236
           E                  P  E    R  H  +P P+     LP   GP+  D    L 
Sbjct: 342 EM----------------PPGPEPPTSRKMHLAEPGPQS----LPLLLGPEPNDLASGLY 381

Query: 237 PGQVKFVLGPTPARRHMVKCQGLC-----PSLH---DPPHHNNNNEAPSECP 280
               K   GP P   H+   + LC     P+LH     PH    + +P+  P
Sbjct: 382 ASVCKRASGP-PGNEHLY--ENLCVLEASPTLHGGEPEPHEGPGSRSPTTSP 430


>gi|41406050 docking protein 2 [Homo sapiens]
          Length = 412

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 32/82 (39%), Positives = 44/82 (53%), Gaps = 7/82 (8%)

Query: 57  WPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQDLMQCNSINVMEEP 116
           WPY  LRR+G D   FSFE+GRRC +G+G F F+  +  EIF  L++     +I+  +  
Sbjct: 194 WPYRFLRRFGRDKVTFSFEAGRRCVSGEGNFEFETRQGNEIFLALEE-----AISAQKNA 248

Query: 117 VIITRNSHPAEL--DLPRAPQP 136
              T    PA +   LPR   P
Sbjct: 249 APATPQPQPATIPASLPRPDSP 270


>gi|20070302 docking protein 4 [Homo sapiens]
          Length = 326

 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 25/68 (36%), Positives = 39/68 (57%), Gaps = 3/68 (4%)

Query: 34  GSGVMELTQSELVL---HLHRREAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFK 90
           G   +++T   + L   H  R + V WP   LRRYG D+  F+FE+GR C  G+G++ F+
Sbjct: 153 GECKLQITHENIYLWDIHNPRVKLVSWPLCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQ 212

Query: 91  CSRAEEIF 98
               E+I+
Sbjct: 213 TQEGEQIY 220


>gi|29544726 docking protein 5 [Homo sapiens]
          Length = 306

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 22/48 (45%), Positives = 32/48 (66%)

Query: 51  RREAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIF 98
           R + + WP   LRRYG D+  F+FE+GR C+TG+G+F F+    E I+
Sbjct: 173 RVKLISWPLSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDGEAIY 220


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 99/409 (24%), Positives = 140/409 (34%), Gaps = 63/409 (15%)

Query: 124  HPAELDLPRAPQPPNALGYTVSSFSNGCPGEGPRFSAPRRLSTS-SLRHPSLGEESTHAL 182
            H A+    R    P   G  +   S G   +   + AP  +  S SL  P   +      
Sbjct: 866  HRAQPSYERPSFLPPGPGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPT 925

Query: 183  IAPDEQSHTYVNTPASEDDHRRGRHCLQPLPEGQAPFLPQARGP-DQRDPQVFLQPGQVK 241
             +P E  ++    P+S      GR  L P P G  PF P + GP     P  F  P    
Sbjct: 926  TSPPEPPYSTPPVPSSS-----GR--LTPSPRG-GPFNPGSGGPLPASSPASFDGPSPPD 977

Query: 242  FVLGPTPARRHMVKCQGLCPSLHDPPHHNNNNEAPSE---CPAQPKCTYENVTGGL---- 294
              +G     + +     L P+ H PPHH++++  P +     A P    E  TGG     
Sbjct: 978  TRVGSR--EKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDP 1035

Query: 295  --------------WRGAGWRLSPEEP--------GWNGLAHRRAALLHYENLPPLPPVW 332
                          WRG G   +P  P        G  G + +  AL +++    LPP  
Sbjct: 1036 PPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQ----LPPRA 1091

Query: 333  ESQAQQLGGEAGDDGDSR-------DGLTPSSNGFPDGEEDETPLQ-KPTSTRAAIRSHG 384
             S A  +   +G             +G      G P      +P   +P    AA     
Sbjct: 1092 ASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKN 1151

Query: 385  SFPVPLTRRRGSPRVFNFDFRRPG----PEPPRQLNYIQVELKGWGGDRPKGPQNPSSPQ 440
            S P+P T    +P   +      G     EPP Q    +    G GG     P    SP 
Sbjct: 1152 SIPIP-TIIIKAPSTSSSGRSSQGSSTEAEPPTQ---PEPTGGGGGGGSSPSPAPAMSPV 1207

Query: 441  APMPTTHPARSSDS-YAVIDLKKTVAMSNLQRALPRDDGTARKTRHNST 488
             P P+  P  +S S  A +D       + L  A  R+ G   + R  ST
Sbjct: 1208 PPSPSPVPTPASPSGPATLDFTSQFGAA-LVGAARREGGWQNEARRRST 1255


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
           sapiens]
          Length = 2715

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 43/154 (27%), Positives = 66/154 (42%), Gaps = 11/154 (7%)

Query: 326 PPLPPVWESQAQQLGGEAGDDGDSRDGLTPSSNGFPDGEEDETPLQKPTSTRAAIRSHGS 385
           PPL P    +A++    AG +G S    TPS+     G  +++P   P ST   +++   
Sbjct: 472 PPLTP--SQRAEREAARAGPEGTSPPTPTPSTA--TGGPPEDSPTVAPKST-TFLKNIRQ 526

Query: 386 FPVPLTRRRGSPRVFNFDFRRPGPEPPRQLNY-IQVELKGWGGDRPKGPQNP----SSPQ 440
           F +P+   R S RV     R    +PP+     +   L+      P  PQ P    S P+
Sbjct: 527 FIMPVVSARSS-RVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPR 585

Query: 441 APMPTTHPARSSDSYAVIDLKKTVAMSNLQRALP 474
           AP P + P    +    I  + T   ++L R LP
Sbjct: 586 APTPPSTPVPLPEKRRSILREPTFRWTSLTRELP 619


>gi|111185957 downstream of tyrosine kinase 7 [Homo sapiens]
          Length = 504

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 64/239 (26%), Positives = 91/239 (38%), Gaps = 36/239 (15%)

Query: 20  KFKVTNVDDEGVELGSGVMELTQSELVLHLHRREAV--RWPYLCLRRYGYDSNLFSFESG 77
           +F VT      +E G   + L    LVL      AV  +W    LRRYG   + F FE G
Sbjct: 113 RFHVTVAPGTKLESGPATLHLCNDVLVLARDIPPAVTGQWKLSDLRRYGAVPSGFIFEGG 172

Query: 78  RRCQTGQGIFAFKCSRAEEIFNLLQDLMQCNSINVMEEPV----IITRNSHP----AELD 129
            RC    G+F    +  E+I  L   +++   I+  + P     ++   S P     E  
Sbjct: 173 TRCGYWAGVFFLSSAEGEQISFLFDCIVR--GISPTKGPFGLRPVLPDPSPPGPSTVEER 230

Query: 130 LPRAPQPPNALGYTVSSFSN-GCPGEGPRFSAPRRLSTSSLRHPSLGEESTHALIAPDEQ 188
           + +       L   +S  S+ G PG G      R LS+SS     L   ++  L A  EQ
Sbjct: 231 VAQEALETLQLEKRLSLLSHAGRPGSG---GDDRSLSSSSSEASHLDVSASSRLTAWPEQ 287

Query: 189 SHTYVNTPASEDDHRRGRHCLQPLPEGQAPFLPQARGP----DQRDPQVFLQPGQVKFV 243
           S +  +T                  EG  P   QA G       R P   L+P Q++ V
Sbjct: 288 SSSSASTS----------------QEGPRPAAAQAAGEAMVGASRPPPKPLRPRQLQEV 330


>gi|149944516 tet oncogene family member 3 [Homo sapiens]
          Length = 1660

 Score = 37.7 bits (86), Expect = 0.024
 Identities = 37/129 (28%), Positives = 55/129 (42%), Gaps = 27/129 (20%)

Query: 331 VWESQAQQLGGEAGDDGDSRDGLTPSSNGFPDGEEDETPLQKPTSTRAAIRSHGSFPVPL 390
           ++E+  +++  EAG++     G  P   G   G ED   LQ    T  A+  HG      
Sbjct: 85  LYETFNREMSREAGNNSR---GPRPGPEGCSAGSEDLDTLQ----TALALARHGM----- 132

Query: 391 TRRRGSPRVFNFDFRRPGPEPPRQLNYIQVELKG----WGGDRPK--GPQNPSSPQAPMP 444
                 P   N D    GPE P  L +++ ++K      G +RP+  GP  P     P P
Sbjct: 133 -----KPPNCNCD----GPECPDYLEWLEGKIKSVVMEGGEERPRLPGPLPPGEAGLPAP 183

Query: 445 TTHPARSSD 453
           +T P  SS+
Sbjct: 184 STRPLLSSE 192


>gi|56117844 synovial sarcoma translocation, chromosome 18 isoform 2
           [Homo sapiens]
          Length = 387

 Score = 36.6 bits (83), Expect = 0.053
 Identities = 49/208 (23%), Positives = 77/208 (37%), Gaps = 25/208 (12%)

Query: 248 PARRHMVKCQGLCPSLHDPPHHNNNNEAPSECPA---QPKCTYENVTGGLWRGAGWRLSP 304
           P +  M   QG     + P    N +  P++ P    QP     N+     +G G     
Sbjct: 174 PVQNQMTMSQGQPMGNYGP--RPNMSMQPNQGPMMHQQPPSQQYNMP----QGGGQHYQG 227

Query: 305 EEP--GWNGLAHRRAALLHYENLPPLPPVWESQAQQLGGEAGDDGD--SRDGLTP----S 356
           ++P  G  G  ++   ++    +PP  P  +   QQ  G+    GD  S  G  P    +
Sbjct: 228 QQPPMGMMGQVNQGNHMMGQRQIPPYRPPQQGPPQQYSGQEDYYGDQYSHGGQGPPEGMN 287

Query: 357 SNGFPDGE----EDETPLQKPTSTRAAIRSHGSFPVPLTRRRGSPRVFNFDFRRPGPEPP 412
              +PDG     + +   Q P   +        +P       G  + +      PGP+ P
Sbjct: 288 QQYYPDGNSQYGQQQDAYQGPPPQQGYPPQQQQYPGQ-QGYPGQQQGYGPSQGGPGPQYP 346

Query: 413 RQLNYIQVELKGWGGDRPKGPQNPSSPQ 440
              NY Q + + +GG RP  P  P  PQ
Sbjct: 347 ---NYPQGQGQQYGGYRPTQPGPPQPPQ 371


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 36.6 bits (83), Expect = 0.053
 Identities = 38/127 (29%), Positives = 51/127 (40%), Gaps = 11/127 (8%)

Query: 212  LPEGQAPFLPQARGPDQRDPQVFLQPGQVKFVLGPTPARRHMVKCQGLCPSLHDP----- 266
            LP G A  L  A+ P  + P     PG   FV  P+P R    +  G  PSL  P     
Sbjct: 2498 LPAGPAGEL-HAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGE-PSLKPPVPQPG 2555

Query: 267  ---PHHNNNNEAPSECPAQPKCTYENVTGGLWRGAGWRLSPEEPGWNGLAHRRAALLHYE 323
               PH  N++  P     +P+ T   V  G +  +G  L P   G  G ++  + L    
Sbjct: 2556 LPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSS-GSTGESYGLSPLRPPS 2614

Query: 324  NLPPLPP 330
             LPP  P
Sbjct: 2615 VLPPPAP 2621



 Score = 33.1 bits (74), Expect = 0.59
 Identities = 16/46 (34%), Positives = 23/46 (50%), Gaps = 4/46 (8%)

Query: 407  PGPEPPRQLNYI----QVELKGWGGDRPKGPQNPSSPQAPMPTTHP 448
            P PEPP Q +Y      ++++      P+ P  P SP AP P + P
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPP 4929


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 35.4 bits (80), Expect = 0.12
 Identities = 44/168 (26%), Positives = 56/168 (33%), Gaps = 9/168 (5%)

Query: 304 PEEPGWNGLAHRRAAL-LHYENLPPLPPVWESQAQQLGGEAGDDGDSRDGLTPSSNGFPD 362
           P  P  NGL      L L     P +P     +    GG  G  G       P   G PD
Sbjct: 174 PFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPD 233

Query: 363 GEEDETPLQKPTSTRAAIRSHGSFPVPLTRRRGSPRVFNFDFRRPGPEPP-RQLNYIQVE 421
                 P   PT       S  +        + SP+++NF    PGP PP R L      
Sbjct: 234 --PPPPPRHLPTQFNLLASSSAA---AAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTV 288

Query: 422 LKGWGGDRPKGPQNPSSPQAPMPTTHPARSSDSYAVIDLKKTVAMSNL 469
           +K +   RP   Q P  P       H      SY  +  +  +A S L
Sbjct: 289 IKHY--QRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPL 334


>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
          Length = 1526

 Score = 35.0 bits (79), Expect = 0.16
 Identities = 55/210 (26%), Positives = 81/210 (38%), Gaps = 35/210 (16%)

Query: 131  PRAPQPPNALGYTVSSFSNGCPGEGP------RFSAPRRLSTSSLRHPSLGEESTHALIA 184
            P+ P PP+  G +  S   G  G GP      R + P R    S   P     ++   + 
Sbjct: 1118 PQRPPPPS--GRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISA--PQSHARASAGRLT 1173

Query: 185  PDEQSHTYVNTPASEDDHRRGRHCLQPLPEGQAPFLPQARGPDQRDPQVFLQPGQVKFVL 244
            P+ QS T   +  S             LPE   P  PQA  P    PQ  L P   +   
Sbjct: 1174 PESQSKTSETSKGSTF-----------LPE---PLKPQAAFP----PQSSLPPPAQRLQE 1215

Query: 245  GPTPARRHMVKCQGLCPSLHDPPH----HNNNNEAPSECPAQPKCTYENVTGGLWRGAGW 300
               P    M +  G  P+L  PP       +++  PSE  +QP+     ++ G  R +  
Sbjct: 1216 PLVPVAAPMPQ-SGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGK-RESPL 1273

Query: 301  RLSP-EEPGWNGLAHRRAALLHYENLPPLP 329
            ++ P E+  +N LA  +A L    +  P P
Sbjct: 1274 KIDPFEDLSFNLLAVSKAQLSVQTSPVPTP 1303


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 34.7 bits (78), Expect = 0.20
 Identities = 25/94 (26%), Positives = 34/94 (36%), Gaps = 22/94 (23%)

Query: 361 PDGEEDETPLQKPTSTRAAIRSHGSFPVPLTRRRGSPRVFNFDFRRPGPEPPRQLNYIQV 420
           P G++  +P   P   +      G+ P       G P+         GP P         
Sbjct: 143 PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ---------GPPPQ-------- 185

Query: 421 ELKGWGGDRPKGPQNPSSPQAPMPTTHPARSSDS 454
                GG +P+GP  P  PQ P P    +RSS S
Sbjct: 186 -----GGKKPQGPPPPGKPQGPPPQGDKSRSSQS 214



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 25/94 (26%), Positives = 34/94 (36%), Gaps = 22/94 (23%)

Query: 361 PDGEEDETPLQKPTSTRAAIRSHGSFPVPLTRRRGSPRVFNFDFRRPGPEPPRQLNYIQV 420
           P G++  +P   P   +      G+ P       G P+         GP P         
Sbjct: 82  PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ---------GPPPQ-------- 124

Query: 421 ELKGWGGDRPKGPQNPSSPQAPMPTTHPARSSDS 454
                GG+RP+GP  P  PQ P P    +RS  S
Sbjct: 125 -----GGNRPQGPPPPGKPQGPPPQGDKSRSPRS 153



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 13/29 (44%), Positives = 17/29 (58%)

Query: 426 GGDRPKGPQNPSSPQAPMPTTHPARSSDS 454
           GG++P+GP  P  PQ P P    +RS  S
Sbjct: 64  GGNKPQGPPPPGKPQGPPPQGDKSRSPRS 92


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 33.9 bits (76), Expect = 0.35
 Identities = 63/270 (23%), Positives = 95/270 (35%), Gaps = 67/270 (24%)

Query: 216 QAPFLPQARGPDQRDPQVFLQPGQVKFVLGPTPARRHMVKCQGLCPSLHDP--------- 266
           Q P    A+ P QRD               P   +  +V+ + + PSL  P         
Sbjct: 263 QTPQTDHAKLPLQRDAS------------RPQTKQADIVRGESVKPSLPSPSKPPIQQPT 310

Query: 267 --------PHHNNNNEAPSECPAQPKCTYENVTGGLWRGAGWRLSPEEPGWNGLAHRRAA 318
                   P H  +   P++ PAQP      +T  L +  G    P +P           
Sbjct: 311 PGKPPAQQPGHEKSQPGPAKPPAQP----SGLTKPLAQQPGTVKPPVQPPGT-------- 358

Query: 319 LLHYENLPPLPPVWESQ--AQQLGGEAGDDGDSRDGLTPSSNGFPDGEEDETPLQKPTST 376
                  PP  P+  ++  AQQ G E      S +   P +   P G   +TP Q+P   
Sbjct: 359 -----TKPPAQPLGPAKPPAQQTGSEK----PSSEQPGPKALAQPPG-VGKTPAQQPGPA 408

Query: 377 RAAIRSHGSFPVPLTRRRG------SPRVFNFDFRRPGPE--PPRQLNYIQVELKGWGGD 428
           +   +  G+ P PL ++ G      +P       ++PGP   P +Q    +   +  G  
Sbjct: 409 KPPTQQVGT-PKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPT 467

Query: 429 RP----KGPQNPSSPQAPMPTTHPARSSDS 454
           +P     GP  P  PQ P P   P +   S
Sbjct: 468 KPPSQLPGPAKP-PPQQPGPAKPPPQQPGS 496


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 33.9 bits (76), Expect = 0.35
 Identities = 63/270 (23%), Positives = 95/270 (35%), Gaps = 67/270 (24%)

Query: 216 QAPFLPQARGPDQRDPQVFLQPGQVKFVLGPTPARRHMVKCQGLCPSLHDP--------- 266
           Q P    A+ P QRD               P   +  +V+ + + PSL  P         
Sbjct: 263 QTPQTDHAKLPLQRDAS------------RPQTKQADIVRGESVKPSLPSPSKPPIQQPT 310

Query: 267 --------PHHNNNNEAPSECPAQPKCTYENVTGGLWRGAGWRLSPEEPGWNGLAHRRAA 318
                   P H  +   P++ PAQP      +T  L +  G    P +P           
Sbjct: 311 PGKPPAQQPGHEKSQPGPAKPPAQP----SGLTKPLAQQPGTVKPPVQPPGT-------- 358

Query: 319 LLHYENLPPLPPVWESQ--AQQLGGEAGDDGDSRDGLTPSSNGFPDGEEDETPLQKPTST 376
                  PP  P+  ++  AQQ G E      S +   P +   P G   +TP Q+P   
Sbjct: 359 -----TKPPAQPLGPAKPPAQQTGSEK----PSSEQPGPKALAQPPG-VGKTPAQQPGPA 408

Query: 377 RAAIRSHGSFPVPLTRRRG------SPRVFNFDFRRPGPE--PPRQLNYIQVELKGWGGD 428
           +   +  G+ P PL ++ G      +P       ++PGP   P +Q    +   +  G  
Sbjct: 409 KPPTQQVGT-PKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPT 467

Query: 429 RP----KGPQNPSSPQAPMPTTHPARSSDS 454
           +P     GP  P  PQ P P   P +   S
Sbjct: 468 KPPSQLPGPAKP-PPQQPGPAKPPPQQPGS 496


>gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo
           sapiens]
          Length = 384

 Score = 33.5 bits (75), Expect = 0.45
 Identities = 55/208 (26%), Positives = 70/208 (33%), Gaps = 39/208 (18%)

Query: 246 PTPARRHMVKCQGLCPSLHDPPHHNNNNEAPSECPAQPKCTYENVTGGLWRGAGWRLSPE 305
           P P  R     +   P    PP  + +    S  P +P              +G RL P 
Sbjct: 73  PHPDSRTRPAARPPHPRTRSPPGRSGSGTTFSAVPPRPS----------QHQSGSRLRPA 122

Query: 306 EPGWN-GLAHRRAALLHYENLPPLPPVWESQAQQLGGEAGDDGDSRDGLTPSSNGFPDGE 364
            PG   G +  RA+        P P   ++ A+   G A   G       P S G    +
Sbjct: 123 APGPRPGCSSARAS--------PAPAAPQAAARTAPGRAASGGSG-----PGSRGQGSDQ 169

Query: 365 EDETPLQKPTSTRAAIRSHGSFPVPLTRRR--GSPRVFNFDFRRPG-PEPPRQLNYIQVE 421
               P      +RA     G  P PLT RR   +PR     FRRPG P   R  +     
Sbjct: 170 VGARP------SRA-----GGQPPPLTCRRCRAAPRRSARPFRRPGLPLKSRPGSGTGAR 218

Query: 422 LKG-WGGDRPKGPQNPSSPQAPMPTTHP 448
             G WG     G    SSP A   +  P
Sbjct: 219 SCGTWGSGGGPGTAAASSPSADFSSDSP 246


>gi|239743279 PREDICTED: hypothetical protein XP_002342816 [Homo
           sapiens]
          Length = 384

 Score = 33.5 bits (75), Expect = 0.45
 Identities = 55/208 (26%), Positives = 70/208 (33%), Gaps = 39/208 (18%)

Query: 246 PTPARRHMVKCQGLCPSLHDPPHHNNNNEAPSECPAQPKCTYENVTGGLWRGAGWRLSPE 305
           P P  R     +   P    PP  + +    S  P +P              +G RL P 
Sbjct: 73  PHPDSRTRPAARPPHPRTRSPPGRSGSGTTFSAVPPRPS----------QHQSGSRLRPA 122

Query: 306 EPGWN-GLAHRRAALLHYENLPPLPPVWESQAQQLGGEAGDDGDSRDGLTPSSNGFPDGE 364
            PG   G +  RA+        P P   ++ A+   G A   G       P S G    +
Sbjct: 123 APGPRPGCSSARAS--------PAPAAPQAAARTAPGRAASGGSG-----PGSRGQGSDQ 169

Query: 365 EDETPLQKPTSTRAAIRSHGSFPVPLTRRR--GSPRVFNFDFRRPG-PEPPRQLNYIQVE 421
               P      +RA     G  P PLT RR   +PR     FRRPG P   R  +     
Sbjct: 170 VGARP------SRA-----GGQPPPLTCRRCRAAPRRSARPFRRPGLPLKSRPGSGTGAR 218

Query: 422 LKG-WGGDRPKGPQNPSSPQAPMPTTHP 448
             G WG     G    SSP A   +  P
Sbjct: 219 SCGTWGSGGGPGTAAASSPSADFSSDSP 246


>gi|239508962 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 384

 Score = 33.5 bits (75), Expect = 0.45
 Identities = 55/208 (26%), Positives = 70/208 (33%), Gaps = 39/208 (18%)

Query: 246 PTPARRHMVKCQGLCPSLHDPPHHNNNNEAPSECPAQPKCTYENVTGGLWRGAGWRLSPE 305
           P P  R     +   P    PP  + +    S  P +P              +G RL P 
Sbjct: 73  PHPDSRTRPAARPPHPRTRSPPGRSGSGTTFSAVPPRPS----------QHQSGSRLRPA 122

Query: 306 EPGWN-GLAHRRAALLHYENLPPLPPVWESQAQQLGGEAGDDGDSRDGLTPSSNGFPDGE 364
            PG   G +  RA+        P P   ++ A+   G A   G       P S G    +
Sbjct: 123 APGPRPGCSSARAS--------PAPAAPQAAARTAPGRAASGGSG-----PGSRGQGSDQ 169

Query: 365 EDETPLQKPTSTRAAIRSHGSFPVPLTRRR--GSPRVFNFDFRRPG-PEPPRQLNYIQVE 421
               P      +RA     G  P PLT RR   +PR     FRRPG P   R  +     
Sbjct: 170 VGARP------SRA-----GGQPPPLTCRRCRAAPRRSARPFRRPGLPLKSRPGSGTGAR 218

Query: 422 LKG-WGGDRPKGPQNPSSPQAPMPTTHP 448
             G WG     G    SSP A   +  P
Sbjct: 219 SCGTWGSGGGPGTAAASSPSADFSSDSP 246


>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
          Length = 2803

 Score = 33.1 bits (74), Expect = 0.59
 Identities = 87/345 (25%), Positives = 114/345 (33%), Gaps = 58/345 (16%)

Query: 120  TRNSHPAELDLPRAPQPPNALGYTVSSFSNGCPGEGPRFSAPRRLSTSSLRHPSLGEEST 179
            TR  H   L++ +AP   ++L    S  S G P      + PR  S      P+L E S+
Sbjct: 2210 TRTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAP---LLSNLPRPAS------PALSEGSS 2260

Query: 180  HALIAPDEQSHTYVNTPASEDDHRRGRHCLQPLPEGQAPFLPQARGPDQRDPQVFLQPGQ 239
                 P   S     +P+ E   +     L P  E      P A       P     P  
Sbjct: 2261 SEATTPVISSVAERFSPSLEAAEQESGE-LDPGME------PAAHSLWDLTPLSPAPPAS 2313

Query: 240  VKFVLGPTPARRHMVKCQGLCPSLHDP--PHHNNNNEAPSECPAQPKCTYENVTGGLWRG 297
            +   L P P+         L   + D   P H   +EA +E P+  +   E+        
Sbjct: 2314 LDLALAPAPS---------LPGDMGDGILPCHLECSEAATEKPSPFQVPSEDCAA----N 2360

Query: 298  AGWRLSPEEPGWNGLAHRRAALLHYENLPPLP-PVWESQAQQLGGEAGDDGDSRDGLTPS 356
                 SP  PG         A    EN      P WE  A   G E     D+   L+P 
Sbjct: 2361 GPTETSPNPPG--------PAPAKAENEEAAACPAWERGAWPEGAERSSRPDTL--LSPE 2410

Query: 357  SNGFPDGEEDETPLQKPTSTRAAIRSHGSFPVPLTRRRGSPRVFNFDFRRPGPEPP---- 412
                P G     P        A  +   + P P  R   SP   N       P PP    
Sbjct: 2411 QPVCPAGGSGGPPSSASPEVEAGPQGCATEPRP-HRGELSPSFLN------PPLPPSIDD 2463

Query: 413  RQLNYIQVELKGWGGDRPKGPQNPSSPQAPMPTTH---PARSSDS 454
            R L+  +V L G GG R  G   P +   P P T    P  +SDS
Sbjct: 2464 RDLSTEEVRLVGRGGRRRVG--GPGTTGGPCPVTDETPPTSASDS 2506


>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
          Length = 1612

 Score = 32.7 bits (73), Expect = 0.77
 Identities = 54/216 (25%), Positives = 83/216 (38%), Gaps = 35/216 (16%)

Query: 127  ELDLPRAPQPPNA--LGYTVSSFSNGCPGEGP------RFSAPRRLSTSSLRHPSLGEES 178
            E++ P++P       +G +  S   G  G GP      R + P R    S   P     +
Sbjct: 1196 EMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISA--PQSHARA 1253

Query: 179  THALIAPDEQSHTYVNTPASEDDHRRGRHCLQPLPEGQAPFLPQARGPDQRDPQVFLQPG 238
            +   + P+ QS T   +  S             LPE   P  PQA  P    PQ  L P 
Sbjct: 1254 SAGRLTPESQSKTSETSKGSTF-----------LPE---PLKPQAAFP----PQSSLPPP 1295

Query: 239  QVKFVLGPTPARRHMVKCQGLCPSLHDPPH----HNNNNEAPSECPAQPKCTYENVTGGL 294
              +      P    M +  G  P+L  PP       +++  PSE  +QP+     ++ G 
Sbjct: 1296 AQRLQEPLVPVAAPMPQ-SGPQPNLETPPQPPPRSRSSHSLPSEASSQPQVKTNGISDGK 1354

Query: 295  WRGAGWRLSP-EEPGWNGLAHRRAALLHYENLPPLP 329
             R +  ++ P E+  +N LA  +A L    +  P P
Sbjct: 1355 -RESPLKIDPFEDLSFNLLAVSKAQLSVQTSPVPTP 1389


>gi|222352183 neural precursor cell expressed, developmentally
           down-regulated 4-like isoform 2 [Homo sapiens]
          Length = 854

 Score = 32.7 bits (73), Expect = 0.77
 Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 2/37 (5%)

Query: 306 EPGWNGLAHRRAALLHYENLPP--LPPVWESQAQQLG 340
           E GW  +    +A  H E LPP  LPP WE +   LG
Sbjct: 50  EHGWEVVDSNDSASQHQEELPPPPLPPGWEEKVDNLG 86


>gi|21361472 neural precursor cell expressed, developmentally
           down-regulated 4-like isoform 3 [Homo sapiens]
          Length = 955

 Score = 32.7 bits (73), Expect = 0.77
 Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 2/37 (5%)

Query: 306 EPGWNGLAHRRAALLHYENLPP--LPPVWESQAQQLG 340
           E GW  +    +A  H E LPP  LPP WE +   LG
Sbjct: 171 EHGWEVVDSNDSASQHQEELPPPPLPPGWEEKVDNLG 207


>gi|222352094 neural precursor cell expressed, developmentally
           down-regulated 4-like isoform 6 [Homo sapiens]
          Length = 834

 Score = 32.7 bits (73), Expect = 0.77
 Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 2/37 (5%)

Query: 306 EPGWNGLAHRRAALLHYENLPP--LPPVWESQAQQLG 340
           E GW  +    +A  H E LPP  LPP WE +   LG
Sbjct: 50  EHGWEVVDSNDSASQHQEELPPPPLPPGWEEKVDNLG 86


>gi|222352092 neural precursor cell expressed, developmentally
           down-regulated 4-like isoform 6 [Homo sapiens]
          Length = 834

 Score = 32.7 bits (73), Expect = 0.77
 Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 2/37 (5%)

Query: 306 EPGWNGLAHRRAALLHYENLPP--LPPVWESQAQQLG 340
           E GW  +    +A  H E LPP  LPP WE +   LG
Sbjct: 50  EHGWEVVDSNDSASQHQEELPPPPLPPGWEEKVDNLG 86


>gi|222352090 neural precursor cell expressed, developmentally
           down-regulated 4-like isoform 5 [Homo sapiens]
          Length = 947

 Score = 32.7 bits (73), Expect = 0.77
 Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 2/37 (5%)

Query: 306 EPGWNGLAHRRAALLHYENLPP--LPPVWESQAQQLG 340
           E GW  +    +A  H E LPP  LPP WE +   LG
Sbjct: 163 EHGWEVVDSNDSASQHQEELPPPPLPPGWEEKVDNLG 199


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.135    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,261,231
Number of Sequences: 37866
Number of extensions: 1529149
Number of successful extensions: 5918
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 102
Number of HSP's that attempted gapping in prelim test: 5710
Number of HSP's gapped (non-prelim): 277
length of query: 492
length of database: 18,247,518
effective HSP length: 106
effective length of query: 386
effective length of database: 14,233,722
effective search space: 5494216692
effective search space used: 5494216692
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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