Guide to the Human Genome
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Search of human proteins with 56682938

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|56682938 A kinase (PRKA) anchor protein 14 isoform b [Homo
sapiens]
         (137 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|56682938 A kinase (PRKA) anchor protein 14 isoform b [Homo sa...   279   4e-76
gi|30520346 A kinase (PRKA) anchor protein 14 isoform a [Homo sa...   208   1e-54
gi|56682940 A kinase (PRKA) anchor protein 14 isoform c [Homo sa...   176   7e-45
gi|164663830 FGGY carbohydrate kinase domain containing isoform ...    31   0.28 
gi|164663828 FGGY carbohydrate kinase domain containing isoform ...    31   0.28 
gi|166362737 erythrocyte membrane protein band 4.2 isoform 2 [Ho...    30   0.48 
gi|166362735 erythrocyte membrane protein band 4.2 isoform 1 [Ho...    30   0.48 
gi|225579078 retinol dehydrogenase 13 isoform 1 [Homo sapiens]         28   1.8  
gi|19923931 retinol dehydrogenase 13 isoform 2 [Homo sapiens]          28   1.8  
gi|54633319 PDZ domain-containing guanine nucleotide exchange fa...    27   4.0  
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo...    27   4.0  
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof...    27   4.0  
gi|153945715 myosin VC [Homo sapiens]                                  27   5.3  
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          27   5.3  
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          27   5.3  
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          27   5.3  
gi|45446749 kinesin family member 5A [Homo sapiens]                    27   6.9  
gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens]      27   6.9  
gi|208431757 KLRAQ motif containing 1 isoform 3 [Homo sapiens]         27   6.9  
gi|24308420 KLRAQ motif containing 1 isoform 2 [Homo sapiens]          27   6.9  
gi|208431754 KLRAQ motif containing 1 isoform 1 [Homo sapiens]         27   6.9  
gi|87299628 biorientation of chromosomes in cell division 1-like...    26   9.0  

>gi|56682938 A kinase (PRKA) anchor protein 14 isoform b [Homo
           sapiens]
          Length = 137

 Score =  279 bits (714), Expect = 4e-76
 Identities = 137/137 (100%), Positives = 137/137 (100%)

Query: 1   MSETQNSTSQKAMDEDNKAASQTMPNTQDKNYEDELTQVALALVEDVINYAVKIVEEERN 60
           MSETQNSTSQKAMDEDNKAASQTMPNTQDKNYEDELTQVALALVEDVINYAVKIVEEERN
Sbjct: 1   MSETQNSTSQKAMDEDNKAASQTMPNTQDKNYEDELTQVALALVEDVINYAVKIVEEERN 60

Query: 61  PLKNIKWMTHGEFTVEKGLKQIDEYFSDAPIVVSYVGDHQALVHRPGMVRFRENWQKNLT 120
           PLKNIKWMTHGEFTVEKGLKQIDEYFSDAPIVVSYVGDHQALVHRPGMVRFRENWQKNLT
Sbjct: 61  PLKNIKWMTHGEFTVEKGLKQIDEYFSDAPIVVSYVGDHQALVHRPGMVRFRENWQKNLT 120

Query: 121 DAKYSFMESFPFLFNRV 137
           DAKYSFMESFPFLFNRV
Sbjct: 121 DAKYSFMESFPFLFNRV 137


>gi|30520346 A kinase (PRKA) anchor protein 14 isoform a [Homo
           sapiens]
          Length = 197

 Score =  208 bits (529), Expect = 1e-54
 Identities = 124/197 (62%), Positives = 125/197 (63%), Gaps = 60/197 (30%)

Query: 1   MSETQNSTSQKAMDEDNKAASQTMPNTQDKNYEDELTQVALALVEDVINYAVKIVEEERN 60
           MSETQNSTSQKAMDEDNKAASQTMPNTQDKNYEDELTQVALALVEDVINYAVKIVEEERN
Sbjct: 1   MSETQNSTSQKAMDEDNKAASQTMPNTQDKNYEDELTQVALALVEDVINYAVKIVEEERN 60

Query: 61  PLKNI---------------------------KWMTHG-EFTVEKGLKQ----------- 81
           PLKNI                           K   HG EF   K L             
Sbjct: 61  PLKNIKWMTHGEFTVEKGLKQIDEYFSKCVSKKCWAHGVEFVERKDLIHSFLYIYYVHWS 120

Query: 82  ------------IDEYFS---------DAPIVVSYVGDHQALVHRPGMVRFRENWQKNLT 120
                          YF+         DAPIVVSYVGDHQALVHRPGMVRFRENWQKNLT
Sbjct: 121 ISTADLPVARISAGTYFTMKVSKTKPPDAPIVVSYVGDHQALVHRPGMVRFRENWQKNLT 180

Query: 121 DAKYSFMESFPFLFNRV 137
           DAKYSFMESFPFLFNRV
Sbjct: 181 DAKYSFMESFPFLFNRV 197


>gi|56682940 A kinase (PRKA) anchor protein 14 isoform c [Homo
          sapiens]
          Length = 89

 Score =  176 bits (445), Expect = 7e-45
 Identities = 87/87 (100%), Positives = 87/87 (100%)

Query: 1  MSETQNSTSQKAMDEDNKAASQTMPNTQDKNYEDELTQVALALVEDVINYAVKIVEEERN 60
          MSETQNSTSQKAMDEDNKAASQTMPNTQDKNYEDELTQVALALVEDVINYAVKIVEEERN
Sbjct: 1  MSETQNSTSQKAMDEDNKAASQTMPNTQDKNYEDELTQVALALVEDVINYAVKIVEEERN 60

Query: 61 PLKNIKWMTHGEFTVEKGLKQIDEYFS 87
          PLKNIKWMTHGEFTVEKGLKQIDEYFS
Sbjct: 61 PLKNIKWMTHGEFTVEKGLKQIDEYFS 87


>gi|164663830 FGGY carbohydrate kinase domain containing isoform a
           [Homo sapiens]
          Length = 575

 Score = 31.2 bits (69), Expect = 0.28
 Identities = 17/41 (41%), Positives = 21/41 (51%)

Query: 10  QKAMDEDNKAASQTMPNTQDKNYEDELTQVALALVEDVINY 50
           Q+AM + +K      P  QDK Y D+  QV L LVE    Y
Sbjct: 528 QEAMAKMSKVGKVVFPRLQDKKYYDKKYQVFLKLVEHQKEY 568


>gi|164663828 FGGY carbohydrate kinase domain containing isoform b
           [Homo sapiens]
          Length = 551

 Score = 31.2 bits (69), Expect = 0.28
 Identities = 17/41 (41%), Positives = 21/41 (51%)

Query: 10  QKAMDEDNKAASQTMPNTQDKNYEDELTQVALALVEDVINY 50
           Q+AM + +K      P  QDK Y D+  QV L LVE    Y
Sbjct: 504 QEAMAKMSKVGKVVFPRLQDKKYYDKKYQVFLKLVEHQKEY 544


>gi|166362737 erythrocyte membrane protein band 4.2 isoform 2 [Homo
           sapiens]
          Length = 691

 Score = 30.4 bits (67), Expect = 0.48
 Identities = 17/42 (40%), Positives = 24/42 (57%), Gaps = 5/42 (11%)

Query: 88  DAPI---VVSYVGDHQALVHRPGMVRFRENWQKNLTDAKYSF 126
           DAP+   V+S +G  + L+HR    RFR  W +N   AK+ F
Sbjct: 615 DAPMEDCVISILG--RGLIHRERSYRFRSVWPENTMCAKFQF 654


>gi|166362735 erythrocyte membrane protein band 4.2 isoform 1 [Homo
           sapiens]
          Length = 721

 Score = 30.4 bits (67), Expect = 0.48
 Identities = 17/42 (40%), Positives = 24/42 (57%), Gaps = 5/42 (11%)

Query: 88  DAPI---VVSYVGDHQALVHRPGMVRFRENWQKNLTDAKYSF 126
           DAP+   V+S +G  + L+HR    RFR  W +N   AK+ F
Sbjct: 645 DAPMEDCVISILG--RGLIHRERSYRFRSVWPENTMCAKFQF 684


>gi|225579078 retinol dehydrogenase 13 isoform 1 [Homo sapiens]
          Length = 331

 Score = 28.5 bits (62), Expect = 1.8
 Identities = 26/119 (21%), Positives = 50/119 (42%), Gaps = 23/119 (19%)

Query: 31  NYEDELTQVALALVEDVINYAVKIVEEER---------NPLKNIKWMTHGEFTVEKGLKQ 81
           N+      + LA ++ +  +A KI+EEE            ++   W T   F ++ G+  
Sbjct: 88  NHHVNARHLDLASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNH 147

Query: 82  ----------IDEYFSDAPIVVSYVGDHQALVHRPGMVRFRE-NWQKNLTDAKYSFMES 129
                     +D+  + AP   S + +  +L H  G + F + NWQ    + K ++ +S
Sbjct: 148 LGHFLLTNLLLDKLKASAP---SRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQS 203


>gi|19923931 retinol dehydrogenase 13 isoform 2 [Homo sapiens]
          Length = 260

 Score = 28.5 bits (62), Expect = 1.8
 Identities = 26/119 (21%), Positives = 50/119 (42%), Gaps = 23/119 (19%)

Query: 31  NYEDELTQVALALVEDVINYAVKIVEEER---------NPLKNIKWMTHGEFTVEKGLKQ 81
           N+      + LA ++ +  +A KI+EEE            ++   W T   F ++ G+  
Sbjct: 17  NHHVNARHLDLASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNH 76

Query: 82  ----------IDEYFSDAPIVVSYVGDHQALVHRPGMVRFRE-NWQKNLTDAKYSFMES 129
                     +D+  + AP   S + +  +L H  G + F + NWQ    + K ++ +S
Sbjct: 77  LGHFLLTNLLLDKLKASAP---SRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQS 132


>gi|54633319 PDZ domain-containing guanine nucleotide exchange
           factor I [Homo sapiens]
          Length = 1601

 Score = 27.3 bits (59), Expect = 4.0
 Identities = 19/66 (28%), Positives = 33/66 (50%), Gaps = 7/66 (10%)

Query: 65  IKWMTHGEFTVEKGLKQIDEYFSDA------PIVVSYVGDH-QALVHRPGMVRFRENWQK 117
           + + T  E  ++ G+K ++ +  D+       IV+ +V +H       P M RF E ++K
Sbjct: 445 LTYRTFLESPLDVGIKLLEWFKIDSLRDKVTRIVLLWVNNHFNDFEGDPAMTRFLEEFEK 504

Query: 118 NLTDAK 123
           NL D K
Sbjct: 505 NLEDTK 510


>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
            [Homo sapiens]
          Length = 8749

 Score = 27.3 bits (59), Expect = 4.0
 Identities = 17/77 (22%), Positives = 35/77 (45%), Gaps = 2/77 (2%)

Query: 53   KIVEEERNPLKNIKWMTHGE-FTVEKGLKQIDEYFSDAPIVVSYVGDHQALVHRPGMVRF 111
            K + +    LK +      E  T+EKGL    E+      +  ++ ++Q ++H P   + 
Sbjct: 3773 KEIHDHMEQLKELTSTVRKEHMTLEKGLHLAKEFSDKCKALTQWIAEYQEILHVPEEPKM 3832

Query: 112  RENWQKNLTDAKYSFME 128
             E ++K    +KY  ++
Sbjct: 3833 -ELYEKKAQLSKYKSLQ 3848


>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
            [Homo sapiens]
          Length = 8797

 Score = 27.3 bits (59), Expect = 4.0
 Identities = 17/77 (22%), Positives = 35/77 (45%), Gaps = 2/77 (2%)

Query: 53   KIVEEERNPLKNIKWMTHGE-FTVEKGLKQIDEYFSDAPIVVSYVGDHQALVHRPGMVRF 111
            K + +    LK +      E  T+EKGL    E+      +  ++ ++Q ++H P   + 
Sbjct: 3788 KEIHDHMEQLKELTSTVRKEHMTLEKGLHLAKEFSDKCKALTQWIAEYQEILHVPEEPKM 3847

Query: 112  RENWQKNLTDAKYSFME 128
             E ++K    +KY  ++
Sbjct: 3848 -ELYEKKAQLSKYKSLQ 3863


>gi|153945715 myosin VC [Homo sapiens]
          Length = 1742

 Score = 26.9 bits (58), Expect = 5.3
 Identities = 26/99 (26%), Positives = 40/99 (40%), Gaps = 16/99 (16%)

Query: 49   NYAVKIVEEERNPLKNIKWMTHGEFTVEKGLKQIDEYFSDAP------IVVSY--VGDHQ 100
            N    + +E   PL    W+   + T +   K+I E  +         I+ SY  + D +
Sbjct: 1621 NLQNSLAKETLEPLSQAAWLLQVKKTTDSDAKEIYERCTSLSAVQIIKILNSYTPIDDFE 1680

Query: 101  ALVHRPGMVR-------FRENWQKNLTDAKYSFMESFPF 132
              V  P  VR        RE+  + + D KY F  +FPF
Sbjct: 1681 KRV-TPSFVRKVQALLNSREDSSQLMLDTKYLFQVTFPF 1718


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 26.9 bits (58), Expect = 5.3
 Identities = 9/31 (29%), Positives = 20/31 (64%)

Query: 5   QNSTSQKAMDEDNKAASQTMPNTQDKNYEDE 35
           + S+  K +D+DN++ S ++P+ QD   + +
Sbjct: 142 EGSSDPKDIDQDNRSTSPSIPSPQDNESDSD 172


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 26.9 bits (58), Expect = 5.3
 Identities = 9/31 (29%), Positives = 20/31 (64%)

Query: 5   QNSTSQKAMDEDNKAASQTMPNTQDKNYEDE 35
           + S+  K +D+DN++ S ++P+ QD   + +
Sbjct: 696 EGSSDPKDIDQDNRSTSPSIPSPQDNESDSD 726


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 26.9 bits (58), Expect = 5.3
 Identities = 9/31 (29%), Positives = 20/31 (64%)

Query: 5   QNSTSQKAMDEDNKAASQTMPNTQDKNYEDE 35
           + S+  K +D+DN++ S ++P+ QD   + +
Sbjct: 696 EGSSDPKDIDQDNRSTSPSIPSPQDNESDSD 726


>gi|45446749 kinesin family member 5A [Homo sapiens]
          Length = 1032

 Score = 26.6 bits (57), Expect = 6.9
 Identities = 16/51 (31%), Positives = 26/51 (50%), Gaps = 2/51 (3%)

Query: 16  DNKAASQTMPNTQDKN--YEDELTQVALALVEDVINYAVKIVEEERNPLKN 64
           DN+   + + + Q +N   +DE+ +V  AL E  +NY  K  E E    +N
Sbjct: 462 DNEKVQRELSHLQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQN 512


>gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens]
          Length = 1159

 Score = 26.6 bits (57), Expect = 6.9
 Identities = 20/76 (26%), Positives = 35/76 (46%), Gaps = 10/76 (13%)

Query: 55  VEEERNPLKNIKWMTHGEFTVEKGLKQIDEYFSDAPIVV----SYVGDHQALVHRPGMVR 110
           +++   PLK +K      F+V++GL      F+   + V    S  GD   ++   G + 
Sbjct: 576 IKDTSIPLKILK------FSVDEGLTWSTHNFTSTSVFVDGLLSEPGDETLVMTVFGHIS 629

Query: 111 FRENWQKNLTDAKYSF 126
           FR +W+    D + SF
Sbjct: 630 FRSDWELVKVDFRPSF 645


>gi|208431757 KLRAQ motif containing 1 isoform 3 [Homo sapiens]
          Length = 734

 Score = 26.6 bits (57), Expect = 6.9
 Identities = 19/61 (31%), Positives = 33/61 (54%), Gaps = 8/61 (13%)

Query: 9   SQKAMDEDNKAASQTMPNTQD------KNYEDELTQVALALVEDVINYAVKIVEEERNPL 62
           S++A+ E+ K ASQ +   QD      ++YED+L+ ++  L    +N  +    EE + L
Sbjct: 663 SKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMSDHLCS--MNETLSKQREEIDTL 720

Query: 63  K 63
           K
Sbjct: 721 K 721


>gi|24308420 KLRAQ motif containing 1 isoform 2 [Homo sapiens]
          Length = 769

 Score = 26.6 bits (57), Expect = 6.9
 Identities = 19/61 (31%), Positives = 33/61 (54%), Gaps = 8/61 (13%)

Query: 9   SQKAMDEDNKAASQTMPNTQD------KNYEDELTQVALALVEDVINYAVKIVEEERNPL 62
           S++A+ E+ K ASQ +   QD      ++YED+L+ ++  L    +N  +    EE + L
Sbjct: 698 SKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMSDHLCS--MNETLSKQREEIDTL 755

Query: 63  K 63
           K
Sbjct: 756 K 756


>gi|208431754 KLRAQ motif containing 1 isoform 1 [Homo sapiens]
          Length = 780

 Score = 26.6 bits (57), Expect = 6.9
 Identities = 19/61 (31%), Positives = 33/61 (54%), Gaps = 8/61 (13%)

Query: 9   SQKAMDEDNKAASQTMPNTQD------KNYEDELTQVALALVEDVINYAVKIVEEERNPL 62
           S++A+ E+ K ASQ +   QD      ++YED+L+ ++  L    +N  +    EE + L
Sbjct: 709 SKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMSDHLCS--MNETLSKQREEIDTL 766

Query: 63  K 63
           K
Sbjct: 767 K 767


>gi|87299628 biorientation of chromosomes in cell division 1-like
            [Homo sapiens]
          Length = 3051

 Score = 26.2 bits (56), Expect = 9.0
 Identities = 22/91 (24%), Positives = 41/91 (45%), Gaps = 16/91 (17%)

Query: 2    SETQNSTSQKAMDEDNKAASQTMPNTQDKNYEDELTQVALALVEDVINYAVKIVEEERNP 61
            SET ++TS+   ++D  ++S+T     ++N +D                 +K  EE++  
Sbjct: 2826 SETNSTTSRVMEEKDEYSSSETTGEKPEQNDDD----------------TIKSQEEDQPI 2869

Query: 62   LKNIKWMTHGEFTVEKGLKQIDEYFSDAPIV 92
            +   K     ++ VE  LK  D+  +D  IV
Sbjct: 2870 IIKRKRGRPRKYPVETTLKMKDDSKTDTGIV 2900


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.129    0.367 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,728,130
Number of Sequences: 37866
Number of extensions: 177297
Number of successful extensions: 378
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 367
Number of HSP's gapped (non-prelim): 23
length of query: 137
length of database: 18,247,518
effective HSP length: 91
effective length of query: 46
effective length of database: 14,801,712
effective search space: 680878752
effective search space used: 680878752
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 56 (26.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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