Guide to the Human Genome
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Search of human proteins with 56118217

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|56118217 UDP-galactose-4-epimerase [Homo sapiens]
         (348 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|56118217 UDP-galactose-4-epimerase [Homo sapiens]                  711   0.0  
gi|56237023 UDP-galactose-4-epimerase [Homo sapiens]                  711   0.0  
gi|189083684 UDP-galactose-4-epimerase [Homo sapiens]                 711   0.0  
gi|7657641 TDP-glucose 4,6-dehydratase [Homo sapiens]                  85   1e-16
gi|42516563 UDP-glucuronate decarboxylase 1 [Homo sapiens]             75   9e-14
gi|239745448 PREDICTED: hypothetical protein XP_002343493 [Homo ...    47   2e-05
gi|116268111 short chain dehydrogenase/reductase family 42E, mem...    47   3e-05
gi|4504031 GDP-mannose 4,6-dehydratase [Homo sapiens]                  47   3e-05
gi|239756515 PREDICTED: similar to Putative 3-beta-HSD family pr...    45   7e-05
gi|239751020 PREDICTED: hypothetical protein XP_002347673 [Homo ...    45   7e-05
gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo s...    45   7e-05
gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo sap...    45   7e-05
gi|19923621 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and s...    41   0.002
gi|218563686 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and ...    41   0.002
gi|218563684 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and ...    41   0.002
gi|4504509 3 beta-hydroxysteroid dehydrogenase 2 [Homo sapiens]        40   0.003
gi|4507709 tissue specific transplantation antigen P35B [Homo sa...    40   0.003
gi|4504507 3 beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]        37   0.020
gi|33519455 methionine adenosyltransferase II, beta isoform 2 [H...    32   0.65 
gi|11034825 methionine adenosyltransferase II, beta isoform 1 [H...    32   0.65 
gi|4502419 biliverdin reductase B (flavin reductase (NADPH)) [Ho...    31   1.9  
gi|4504505 hydroxysteroid (17-beta) dehydrogenase 4 [Homo sapiens]     30   3.2  
gi|66773086 SH3-binding kinase 1 [Homo sapiens]                        29   5.5  
gi|126131104 fibrocystin isoform 2 [Homo sapiens]                      28   9.3  
gi|126131102 fibrocystin isoform 1 [Homo sapiens]                      28   9.3  

>gi|56118217 UDP-galactose-4-epimerase [Homo sapiens]
          Length = 348

 Score =  711 bits (1835), Expect = 0.0
 Identities = 348/348 (100%), Positives = 348/348 (100%)

Query: 1   MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV 60
           MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV
Sbjct: 1   MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV 60

Query: 61  EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK 120
           EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK
Sbjct: 61  EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK 120

Query: 121 AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA 180
           AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA
Sbjct: 121 AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA 180

Query: 181 VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD 240
           VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD
Sbjct: 181 VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD 240

Query: 241 YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR 300
           YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR
Sbjct: 241 YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR 300

Query: 301 EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA 348
           EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA
Sbjct: 301 EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA 348


>gi|56237023 UDP-galactose-4-epimerase [Homo sapiens]
          Length = 348

 Score =  711 bits (1835), Expect = 0.0
 Identities = 348/348 (100%), Positives = 348/348 (100%)

Query: 1   MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV 60
           MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV
Sbjct: 1   MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV 60

Query: 61  EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK 120
           EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK
Sbjct: 61  EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK 120

Query: 121 AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA 180
           AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA
Sbjct: 121 AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA 180

Query: 181 VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD 240
           VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD
Sbjct: 181 VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD 240

Query: 241 YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR 300
           YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR
Sbjct: 241 YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR 300

Query: 301 EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA 348
           EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA
Sbjct: 301 EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA 348


>gi|189083684 UDP-galactose-4-epimerase [Homo sapiens]
          Length = 348

 Score =  711 bits (1835), Expect = 0.0
 Identities = 348/348 (100%), Positives = 348/348 (100%)

Query: 1   MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV 60
           MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV
Sbjct: 1   MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV 60

Query: 61  EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK 120
           EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK
Sbjct: 61  EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK 120

Query: 121 AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA 180
           AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA
Sbjct: 121 AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA 180

Query: 181 VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD 240
           VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD
Sbjct: 181 VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD 240

Query: 241 YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR 300
           YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR
Sbjct: 241 YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR 300

Query: 301 EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA 348
           EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA
Sbjct: 301 EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA 348


>gi|7657641 TDP-glucose 4,6-dehydratase [Homo sapiens]
          Length = 350

 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 74/287 (25%), Positives = 132/287 (45%), Gaps = 35/287 (12%)

Query: 2   AEKVLVTGGAGYIGSHTVLELLE--AGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGR- 58
           A++VLVTGGAG+I SH ++ L+E    Y+ + +D              SL+ ++ ++ + 
Sbjct: 17  AKRVLVTGGAGFIASHMIVSLVEDYPNYMIINLDKLDYC--------ASLKNLETISNKQ 68

Query: 59  SVEFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEI 118
           + +F + DI D   ++ LF+      V+HFA    V  S  +  ++  VN+ GT  L+  
Sbjct: 69  NYKFIQGDICDSHFVKLLFETEKIDIVLHFAAQTHVDLSFVRAFEFTYVNVYGTHVLVSA 128

Query: 119 MKAHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTW 178
                V+  ++ S+  VYG       DE+ P    TNPY  SK   E  ++   +  K +
Sbjct: 129 AHEARVEKFIYVSTDEVYGGSLDKEFDESSPKQP-TNPYASSKAAAECFVQSYWEQYK-F 186

Query: 179 NAVLLRYFNPTGAHASGCIGEDPQGIPNNLMP-YVSQVAIGRREALNVFGNDYDTEDGTG 237
             V+ R  N  G H            P  ++P ++S +   R+  ++          G  
Sbjct: 187 PVVITRSSNVYGPHQ----------YPEKVIPKFISLLQHNRKCCIH--------GSGLQ 228

Query: 238 VRDYIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAM 284
            R++++  D+ +  +  L+K K      IYN+GT    SV+Q+ + +
Sbjct: 229 TRNFLYATDVVEAFLTVLKKGKPG---EIYNIGTNFEMSVVQLAKEL 272


>gi|42516563 UDP-glucuronate decarboxylase 1 [Homo sapiens]
          Length = 420

 Score = 75.1 bits (183), Expect = 9e-14
 Identities = 76/330 (23%), Positives = 141/330 (42%), Gaps = 42/330 (12%)

Query: 3   EKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEF 62
           +++L+TGGAG++GSH   +L+  G+   V+DNF    +         R V+   G     
Sbjct: 89  KRILITGGAGFVGSHLTDKLMMDGHEVTVVDNFFTGRK---------RNVEHWIGH---- 135

Query: 63  EEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAH 122
           E  ++++   ++ L+ +     + H A   +    +  P+   + N  GT+ +L + K  
Sbjct: 136 ENFELINHDVVEPLYIEVD--QIYHLASPASPPNYMYNPIKTLKTNTIGTLNMLGLAKRV 193

Query: 123 GVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIE--EMIRDLCQADKTWNA 180
           G + L+ +S++ VYG+P+  P  E +   G  NP G    + E   +   +C A      
Sbjct: 194 GAR-LLLASTSEVYGDPEVHPQSEDY--WGHVNPIGPRACYDEGKRVAETMCYAYMKQEG 250

Query: 181 V---LLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTG 237
           V   + R FN  G         D + + N    ++ Q   G  E L V+G+      G+ 
Sbjct: 251 VEVRVARIFNTFGPRMH---MNDGRVVSN----FILQALQG--EPLTVYGS------GSQ 295

Query: 238 VRDYIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVV 297
            R + +V DL  G +A +            NLG    +++L+  Q ++   G     + +
Sbjct: 296 TRAFQYVSDLVNGLVALMNSNVSS----PVNLGNPEEHTILEFAQLIKNLVGSGSEIQFL 351

Query: 298 ARREGDVAACYANPSLAQEELGWTAALGLD 327
           +  + D      +   A+  LGW   + L+
Sbjct: 352 SEAQDDPQKRKPDIKKAKLMLGWEPVVPLE 381


>gi|239745448 PREDICTED: hypothetical protein XP_002343493 [Homo
           sapiens]
          Length = 422

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 41/155 (26%), Positives = 64/155 (41%), Gaps = 28/155 (18%)

Query: 3   EKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEF 62
           +KVLVTGG GY+G      L ++G   +++D                RR Q       +F
Sbjct: 34  QKVLVTGGGGYLGFSLGSHLAKSGTSVILLDR---------------RRPQWELSPETKF 78

Query: 63  EEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAH 122
            + D+ D+ AL R F+      V H A     G    +      +N+ GT  ++++    
Sbjct: 79  IQADVRDEEALYRAFEGVD--CVFHVASYGMSGAEKLQKEQIESINVGGTKLVIDVCVRR 136

Query: 123 GVKNLVFSSSATVY--GNP---------QYLPLDE 146
            V  L+++S+  V   G P          Y PLDE
Sbjct: 137 RVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDE 171


>gi|116268111 short chain dehydrogenase/reductase family 42E, member
           1 [Homo sapiens]
          Length = 393

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 65/276 (23%), Positives = 108/276 (39%), Gaps = 55/276 (19%)

Query: 3   EKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEF 62
           E VL+TGG+GY G      L + G   ++ D    A     ++PE ++ +Q         
Sbjct: 9   ESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPA----QTIPEGIKFIQG-------- 56

Query: 63  EEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAH 122
              DI     +++ F+      V H A     G           VN+ GT  +L++ +  
Sbjct: 57  ---DIRHLSDVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRR 113

Query: 123 GVKNLVFSSSATVYGNPQ----------YLPLDEAHPTGGCTNPYGKSKFFIEEMIRD-- 170
            V  LV++S+  V    Q          YLPL   HP     + Y ++K   E+ + +  
Sbjct: 114 RVPRLVYTSTFNVIFGGQVIRNGDESLPYLPL-HLHP-----DHYSRTKSIAEQKVLEAN 167

Query: 171 ---LCQADKTWNAVLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFG 227
              L + D       LR   P G +  G    + + +P      VS +  G  +   V+G
Sbjct: 168 ATPLDRGDGVLRTCALR---PAGIYGPG----EQRHLPR----IVSYIEKGLFKF--VYG 214

Query: 228 NDYDTEDGTGVRDYIHVVDLAKGHIAALRKLKEQCG 263
                 D   + +++HV +L + HI A   L+   G
Sbjct: 215 ------DPRSLVEFVHVDNLVQAHILASEALRADKG 244


>gi|4504031 GDP-mannose 4,6-dehydratase [Homo sapiens]
          Length = 372

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 67/308 (21%), Positives = 129/308 (41%), Gaps = 31/308 (10%)

Query: 6   LVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFEEM 65
           L+TG  G  GS+    LLE GY    I    ++F   G +    +  Q     +++    
Sbjct: 27  LITGITGQDGSYLAEFLLEKGYEVHGIVRRSSSF-NTGRIEHLYKNPQAHIEGNMKLHYG 85

Query: 66  DILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHGVK 125
           D+ D   L ++  +     + +      V  S         V+  GT++LL+ +K  G+ 
Sbjct: 86  DLTDSTCLVKIINEVKPTEIYNLGAQSHVKISFDLAEYTADVDGVGTLRLLDAVKTCGLI 145

Query: 126 NLV---FSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTW--NA 180
           N V    +S++ +YG  Q +P  E  P     +PYG +K +   ++ +  +A   +  N 
Sbjct: 146 NSVKFYQASTSELYGKVQEIPQKETTPFYP-RSPYGAAKLYAYWIVVNFREAYNLFAVNG 204

Query: 181 VLLRYFNP-TGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVR 239
           +L  + +P  GA+           +   +   V+++ +G+ E  ++   D         R
Sbjct: 205 ILFNHESPRRGANF----------VTRKISRSVAKIYLGQLECFSLGNLD-------AKR 247

Query: 240 DYIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVAR 299
           D+ H    AK ++ A+  + +      + + TG  +SV + V+      GK I ++   +
Sbjct: 248 DWGH----AKDYVEAMWLMLQNDEPEDFVIATGEVHSVREFVEKSFLHIGKTIVWE--GK 301

Query: 300 REGDVAAC 307
            E +V  C
Sbjct: 302 NENEVGRC 309


>gi|239756515 PREDICTED: similar to Putative 3-beta-HSD family
           protein ENSP00000330812 [Homo sapiens]
          Length = 422

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 40/155 (25%), Positives = 63/155 (40%), Gaps = 28/155 (18%)

Query: 3   EKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEF 62
           +KVLVTGG GY+G      L ++G   +++D                RR Q       +F
Sbjct: 34  QKVLVTGGGGYLGFSLGSHLAKSGTSVILLDR---------------RRPQWELSPETKF 78

Query: 63  EEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAH 122
            + D+ D+ AL   F+      V H A     G    +      +N+ GT  ++++    
Sbjct: 79  IQADVRDEEALYHAFEGVD--CVFHVASYGMSGAEKLQKEQIESINVGGTKLVIDVCVRR 136

Query: 123 GVKNLVFSSSATVY--GNP---------QYLPLDE 146
            V  L+++S+  V   G P          Y PLDE
Sbjct: 137 RVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDE 171


>gi|239751020 PREDICTED: hypothetical protein XP_002347673 [Homo
           sapiens]
          Length = 422

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 40/155 (25%), Positives = 63/155 (40%), Gaps = 28/155 (18%)

Query: 3   EKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEF 62
           +KVLVTGG GY+G      L ++G   +++D                RR Q       +F
Sbjct: 34  QKVLVTGGGGYLGFSLGSHLAKSGTSVILLDR---------------RRPQWELSPETKF 78

Query: 63  EEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAH 122
            + D+ D+ AL   F+      V H A     G    +      +N+ GT  ++++    
Sbjct: 79  IQADVRDEEALYHAFEGVD--CVFHVASYGMSGAEKLQKEQIESINVGGTKLVIDVCVRR 136

Query: 123 GVKNLVFSSSATVY--GNP---------QYLPLDE 146
            V  L+++S+  V   G P          Y PLDE
Sbjct: 137 RVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDE 171


>gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo
           sapiens]
          Length = 373

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 70/264 (26%), Positives = 104/264 (39%), Gaps = 53/264 (20%)

Query: 2   AEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVE 61
           A++  V GG+G++G H V +LL  GY   V D      + G   P+            V 
Sbjct: 37  AKRCTVIGGSGFLGQHMVEQLLARGYAVNVFD-----IQQGFDNPQ------------VR 79

Query: 62  FEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKA 121
           F   D+  +  L    K  +   V H A       S  K L +YRVN  GT  ++E  K 
Sbjct: 80  FFLGDLCSRQDLYPALKGVN--TVFHCASPPP--SSNNKEL-FYRVNYIGTKNVIETCKE 134

Query: 122 HGVKNLVFSSSATVYGNPQYLPLDEAHPTGGC------TNPYGKSKFFIEEMIRDLCQAD 175
            GV+ L+ +SSA+V     +  +D  + T          + Y ++K   E  +      +
Sbjct: 135 AGVQKLILTSSASVI----FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPE 190

Query: 176 KTWNAVLLRYFNPTGAHASGCIG-EDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTED 234
           K         F  T     G  G  DPQ     L+P + + A   +    V GN  +  D
Sbjct: 191 KN--------FLTTAIRPHGIFGPRDPQ-----LVPILIEAARNGKMKF-VIGNGKNLVD 236

Query: 235 GTGVRDYIHVVDLAKGHIAALRKL 258
            T V + +H      GHI A  +L
Sbjct: 237 FTFVENVVH------GHILAAEQL 254


>gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo
           sapiens]
          Length = 373

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 70/264 (26%), Positives = 104/264 (39%), Gaps = 53/264 (20%)

Query: 2   AEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVE 61
           A++  V GG+G++G H V +LL  GY   V D      + G   P+            V 
Sbjct: 37  AKRCTVIGGSGFLGQHMVEQLLARGYAVNVFD-----IQQGFDNPQ------------VR 79

Query: 62  FEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKA 121
           F   D+  +  L    K  +   V H A       S  K L +YRVN  GT  ++E  K 
Sbjct: 80  FFLGDLCSRQDLYPALKGVN--TVFHCASPPP--SSNNKEL-FYRVNYIGTKNVIETCKE 134

Query: 122 HGVKNLVFSSSATVYGNPQYLPLDEAHPTGGC------TNPYGKSKFFIEEMIRDLCQAD 175
            GV+ L+ +SSA+V     +  +D  + T          + Y ++K   E  +      +
Sbjct: 135 AGVQKLILTSSASVI----FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPE 190

Query: 176 KTWNAVLLRYFNPTGAHASGCIG-EDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTED 234
           K         F  T     G  G  DPQ     L+P + + A   +    V GN  +  D
Sbjct: 191 KN--------FLTTAIRPHGIFGPRDPQ-----LVPILIEAARNGKMKF-VIGNGKNLVD 236

Query: 235 GTGVRDYIHVVDLAKGHIAALRKL 258
            T V + +H      GHI A  +L
Sbjct: 237 FTFVENVVH------GHILAAEQL 254


>gi|19923621 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
           steroid delta-isomerase 7 isoform a [Homo sapiens]
          Length = 369

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 50/163 (30%), Positives = 67/163 (41%), Gaps = 35/163 (21%)

Query: 6   LVTGGAGYIGSHTVLELLE----AGYLPVVIDNFHNAFRGGGSLPESLR----RVQELTG 57
           LVTGG G++G H V  LL+     G L V   +        G   E L+    RV  + G
Sbjct: 13  LVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHL-------GPWLEELKTGPVRVTAIQG 65

Query: 58  RSVEFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAV-GESVQKPLDYYRVNLTGTIQLL 116
              +  E+     GA            VIH AGL  V G +   P   + VN+ GT  ++
Sbjct: 66  DVTQAHEVAAAVAGA----------HVVIHTAGLVDVFGRA--SPKTIHEVNVQGTRNVI 113

Query: 117 EIMKAHGVKNLVFSSSATVYGNPQYLPLDEAHP--TGGCTNPY 157
           E     G + LV++SS  V G     P  + HP   G    PY
Sbjct: 114 EACVQTGTRFLVYTSSMEVVG-----PNTKGHPFYRGNEDTPY 151


>gi|218563686 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
           steroid delta-isomerase 7 isoform b [Homo sapiens]
          Length = 196

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 50/163 (30%), Positives = 67/163 (41%), Gaps = 35/163 (21%)

Query: 6   LVTGGAGYIGSHTVLELLE----AGYLPVVIDNFHNAFRGGGSLPESLR----RVQELTG 57
           LVTGG G++G H V  LL+     G L V   +        G   E L+    RV  + G
Sbjct: 13  LVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHL-------GPWLEELKTGPVRVTAIQG 65

Query: 58  RSVEFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAV-GESVQKPLDYYRVNLTGTIQLL 116
              +  E+     GA            VIH AGL  V G +   P   + VN+ GT  ++
Sbjct: 66  DVTQAHEVAAAVAGA----------HVVIHTAGLVDVFGRA--SPKTIHEVNVQGTRNVI 113

Query: 117 EIMKAHGVKNLVFSSSATVYGNPQYLPLDEAHP--TGGCTNPY 157
           E     G + LV++SS  V G     P  + HP   G    PY
Sbjct: 114 EACVQTGTRFLVYTSSMEVVG-----PNTKGHPFYRGNEDTPY 151


>gi|218563684 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
           steroid delta-isomerase 7 isoform b [Homo sapiens]
          Length = 196

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 50/163 (30%), Positives = 67/163 (41%), Gaps = 35/163 (21%)

Query: 6   LVTGGAGYIGSHTVLELLE----AGYLPVVIDNFHNAFRGGGSLPESLR----RVQELTG 57
           LVTGG G++G H V  LL+     G L V   +        G   E L+    RV  + G
Sbjct: 13  LVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHL-------GPWLEELKTGPVRVTAIQG 65

Query: 58  RSVEFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAV-GESVQKPLDYYRVNLTGTIQLL 116
              +  E+     GA            VIH AGL  V G +   P   + VN+ GT  ++
Sbjct: 66  DVTQAHEVAAAVAGA----------HVVIHTAGLVDVFGRA--SPKTIHEVNVQGTRNVI 113

Query: 117 EIMKAHGVKNLVFSSSATVYGNPQYLPLDEAHP--TGGCTNPY 157
           E     G + LV++SS  V G     P  + HP   G    PY
Sbjct: 114 EACVQTGTRFLVYTSSMEVVG-----PNTKGHPFYRGNEDTPY 151


>gi|4504509 3 beta-hydroxysteroid dehydrogenase 2 [Homo sapiens]
          Length = 372

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 55/178 (30%), Positives = 72/178 (40%), Gaps = 23/178 (12%)

Query: 1   MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV 60
           M    LVTG  G +G   V  L+E   L   I     AFR    L E   ++Q  T  +V
Sbjct: 1   MGWSCLVTGAGGLLGQRIVRLLVEEKELKE-IRALDKAFRP--ELREEFSKLQNRTKLTV 57

Query: 61  EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK 120
              E DILD+  L+R  +  S   VIH A +  V     +      VN+ GT  LLE   
Sbjct: 58  L--EGDILDEPFLKRACQDVS--VVIHTACIIDVFGVTHRE-SIMNVNVKGTQLLLEACV 112

Query: 121 AHGVKNLVFSSSATVYGNPQYL----------PLDEAHPTGGCTNPYGKSKFFIEEMI 168
              V   +++SS  V G   Y           PL+   PT     PY  SK   E+ +
Sbjct: 113 QASVPVFIYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPT-----PYPYSKKLAEKAV 165


>gi|4507709 tissue specific transplantation antigen P35B [Homo
           sapiens]
          Length = 321

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 65/263 (24%), Positives = 104/263 (39%), Gaps = 41/263 (15%)

Query: 4   KVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFE 63
           ++LVTGG+G +G              VV D        G  LP             V  +
Sbjct: 9   RILVTGGSGLVGK---------AIQKVVAD--------GAGLPGE-------DWVFVSSK 44

Query: 64  EMDILDQGALQRLFKKYSFMAVIHFAGL-KAVGESVQKPLDYYRVNLTGTIQLLEIMKAH 122
           + D+ D    + LF+K     VIH A +   +  +++  LD++R N+     +L      
Sbjct: 45  DADLTDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEV 104

Query: 123 GVKNLVFSSSATVYGNPQYLPLDEA----HPTGGCTNPYGKSKFFIEEMIRDLCQA-DKT 177
           G + +V   S  ++ +    P+DE      P       Y  +K  I+   R   Q    T
Sbjct: 105 GARKVVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCT 164

Query: 178 WNAVLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTG 237
           + AV+    N  G H +  I ED   +P   + +   +A     AL V+G       G  
Sbjct: 165 FTAVIPT--NVFGPHDNFNI-EDGHVLPG--LIHKVHLAKSSGSALTVWGT------GNP 213

Query: 238 VRDYIHVVDLAKGHIAALRKLKE 260
            R +I+ +DLA+  I  LR+  E
Sbjct: 214 RRQFIYSLDLAQLFIWVLREYNE 236


>gi|4504507 3 beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]
          Length = 373

 Score = 37.4 bits (85), Expect = 0.020
 Identities = 50/173 (28%), Positives = 71/173 (41%), Gaps = 23/173 (13%)

Query: 6   LVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFEEM 65
           LVTG  G++G   +  L++   L   I     AF  G  L E   ++Q  T  +V   E 
Sbjct: 7   LVTGAGGFLGQRIIRLLVKEKELKE-IRVLDKAF--GPELREEFSKLQNKTKLTVL--EG 61

Query: 66  DILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHGVK 125
           DILD+  L+R  +  S   +IH A +  V     +      VN+ GT  LLE      V 
Sbjct: 62  DILDEPFLKRACQDVS--VIIHTACIIDVFGVTHRE-SIMNVNVKGTQLLLEACVQASVP 118

Query: 126 NLVFSSSATVYGNPQYL----------PLDEAHPTGGCTNPYGKSKFFIEEMI 168
             +++SS  V G   Y           PL+   P      PY  SK   E+ +
Sbjct: 119 VFIYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPA-----PYPHSKKLAEKAV 166


>gi|33519455 methionine adenosyltransferase II, beta isoform 2 [Homo
           sapiens]
          Length = 323

 Score = 32.3 bits (72), Expect = 0.65
 Identities = 39/166 (23%), Positives = 66/166 (39%), Gaps = 26/166 (15%)

Query: 4   KVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFE 63
           +VLVTG  G +G     E  +        +N+H    G        RR +       +FE
Sbjct: 19  RVLVTGATGLLGRAVHKEFQQ--------NNWHAVGCG-------FRRARP------KFE 57

Query: 64  EMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHG 123
           ++++LD  A+  +   +    ++H A  +       +P    ++N+  +  L +   A G
Sbjct: 58  QVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAVG 117

Query: 124 VKNLVFSSSATVYG-NPQYLPLDEAHPTGGCTNPYGKSKFFIEEMI 168
              +  SS     G NP Y   D   P     N YGK+K   E+ +
Sbjct: 118 AFLIYISSDYVFDGTNPPYREEDIPAP----LNLYGKTKLDGEKAV 159


>gi|11034825 methionine adenosyltransferase II, beta isoform 1 [Homo
           sapiens]
          Length = 334

 Score = 32.3 bits (72), Expect = 0.65
 Identities = 39/166 (23%), Positives = 66/166 (39%), Gaps = 26/166 (15%)

Query: 4   KVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFE 63
           +VLVTG  G +G     E  +        +N+H    G        RR +       +FE
Sbjct: 30  RVLVTGATGLLGRAVHKEFQQ--------NNWHAVGCG-------FRRARP------KFE 68

Query: 64  EMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHG 123
           ++++LD  A+  +   +    ++H A  +       +P    ++N+  +  L +   A G
Sbjct: 69  QVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAVG 128

Query: 124 VKNLVFSSSATVYG-NPQYLPLDEAHPTGGCTNPYGKSKFFIEEMI 168
              +  SS     G NP Y   D   P     N YGK+K   E+ +
Sbjct: 129 AFLIYISSDYVFDGTNPPYREEDIPAP----LNLYGKTKLDGEKAV 170


>gi|4502419 biliverdin reductase B (flavin reductase (NADPH)) [Homo
           sapiens]
          Length = 206

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 35/142 (24%), Positives = 56/142 (39%), Gaps = 24/142 (16%)

Query: 3   EKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLP-ESLRRVQELTGRSVE 61
           +K+ + G  G  G  T+ + ++AGY   V+       R    LP E  R    + G  ++
Sbjct: 4   KKIAIFGATGQTGLTTLAQAVQAGYEVTVL------VRDSSRLPSEGPRPAHVVVGDVLQ 57

Query: 62  FEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKA 121
             ++D    G            AVI   G +         L    V   G   ++  MKA
Sbjct: 58  AADVDKTVAGQ----------DAVIVLLGTR-------NDLSPTTVMSEGARNIVAAMKA 100

Query: 122 HGVKNLVFSSSATVYGNPQYLP 143
           HGV  +V  +SA +  +P  +P
Sbjct: 101 HGVDKVVACTSAFLLWDPTKVP 122


>gi|4504505 hydroxysteroid (17-beta) dehydrogenase 4 [Homo sapiens]
          Length = 736

 Score = 30.0 bits (66), Expect = 3.2
 Identities = 39/150 (26%), Positives = 68/150 (45%), Gaps = 19/150 (12%)

Query: 5   VLVTGGAGYIGSHTVLELLEAGYLPVVID---NFHNAFRGGGSLPESLRRVQELTGRSV- 60
           VLVTG    +G    L   E G L VV D   +F    +G  +  + +  ++   G++V 
Sbjct: 12  VLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVA 71

Query: 61  ---EFEEMDILDQGALQRLFKKYSFMAVIHFAGL---KAVGESVQKPLD-YYRVNLTGTI 113
                EE + + + AL    +      V++ AG+   ++      +  D  +RV+L G+ 
Sbjct: 72  NYDSVEEGEKVVKTALDAFGR---IDVVVNNAGILRDRSFARISDEDWDIIHRVHLRGSF 128

Query: 114 QLL----EIMKAHGVKNLVFSSSAT-VYGN 138
           Q+     E MK      ++ +SSA+ +YGN
Sbjct: 129 QVTRAAWEHMKKQKYGRIIMTSSASGIYGN 158


>gi|66773086 SH3-binding kinase 1 [Homo sapiens]
          Length = 424

 Score = 29.3 bits (64), Expect = 5.5
 Identities = 22/90 (24%), Positives = 36/90 (40%), Gaps = 6/90 (6%)

Query: 258 LKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARREGDVAACYANPSLAQEE 317
           +  + GCR+  +     Y+  ++ QA  +A G  +   V     G +  C    +     
Sbjct: 197 MTRRVGCRVKRVSGTIPYTAPEVCQA-GRADGLAVDTGVDVWAFGVLIFCVLTGNFP--- 252

Query: 318 LGWTAALGLDRMCEDLWRWQKQNPSGFGTQ 347
             W AA G D   E+  RWQ+    G  +Q
Sbjct: 253 --WEAASGADAFFEEFVRWQRGRLPGLPSQ 280


>gi|126131104 fibrocystin isoform 2 [Homo sapiens]
          Length = 3396

 Score = 28.5 bits (62), Expect = 9.3
 Identities = 20/95 (21%), Positives = 42/95 (44%), Gaps = 6/95 (6%)

Query: 164 IEEMIRDLCQADKTWNAVLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREAL 223
           IEE++   C+ +  W+ +LLR     G   S   G+    + +   P+  + ++  R+  
Sbjct: 539 IEELLAVKCKLEPLWSNILLRLGFERGPEVSNSDGD----LTSGTEPFCGRFSL--RQPR 592

Query: 224 NVFGNDYDTEDGTGVRDYIHVVDLAKGHIAALRKL 258
           ++       + G  +  Y H+    KGH+  + K+
Sbjct: 593 HLVLTPPAAQKGYRLDQYTHLCLAYKGHMNKILKM 627


>gi|126131102 fibrocystin isoform 1 [Homo sapiens]
          Length = 4074

 Score = 28.5 bits (62), Expect = 9.3
 Identities = 20/95 (21%), Positives = 42/95 (44%), Gaps = 6/95 (6%)

Query: 164 IEEMIRDLCQADKTWNAVLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREAL 223
           IEE++   C+ +  W+ +LLR     G   S   G+    + +   P+  + ++  R+  
Sbjct: 539 IEELLAVKCKLEPLWSNILLRLGFERGPEVSNSDGD----LTSGTEPFCGRFSL--RQPR 592

Query: 224 NVFGNDYDTEDGTGVRDYIHVVDLAKGHIAALRKL 258
           ++       + G  +  Y H+    KGH+  + K+
Sbjct: 593 HLVLTPPAAQKGYRLDQYTHLCLAYKGHMNKILKM 627


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,573,353
Number of Sequences: 37866
Number of extensions: 597903
Number of successful extensions: 1076
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1054
Number of HSP's gapped (non-prelim): 29
length of query: 348
length of database: 18,247,518
effective HSP length: 103
effective length of query: 245
effective length of database: 14,347,320
effective search space: 3515093400
effective search space used: 3515093400
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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