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Search of human proteins with 56118217
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|56118217 UDP-galactose-4-epimerase [Homo sapiens]
(348 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|56118217 UDP-galactose-4-epimerase [Homo sapiens] 711 0.0
gi|56237023 UDP-galactose-4-epimerase [Homo sapiens] 711 0.0
gi|189083684 UDP-galactose-4-epimerase [Homo sapiens] 711 0.0
gi|7657641 TDP-glucose 4,6-dehydratase [Homo sapiens] 85 1e-16
gi|42516563 UDP-glucuronate decarboxylase 1 [Homo sapiens] 75 9e-14
gi|239745448 PREDICTED: hypothetical protein XP_002343493 [Homo ... 47 2e-05
gi|116268111 short chain dehydrogenase/reductase family 42E, mem... 47 3e-05
gi|4504031 GDP-mannose 4,6-dehydratase [Homo sapiens] 47 3e-05
gi|239756515 PREDICTED: similar to Putative 3-beta-HSD family pr... 45 7e-05
gi|239751020 PREDICTED: hypothetical protein XP_002347673 [Homo ... 45 7e-05
gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo s... 45 7e-05
gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo sap... 45 7e-05
gi|19923621 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and s... 41 0.002
gi|218563686 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and ... 41 0.002
gi|218563684 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and ... 41 0.002
gi|4504509 3 beta-hydroxysteroid dehydrogenase 2 [Homo sapiens] 40 0.003
gi|4507709 tissue specific transplantation antigen P35B [Homo sa... 40 0.003
gi|4504507 3 beta-hydroxysteroid dehydrogenase 1 [Homo sapiens] 37 0.020
gi|33519455 methionine adenosyltransferase II, beta isoform 2 [H... 32 0.65
gi|11034825 methionine adenosyltransferase II, beta isoform 1 [H... 32 0.65
gi|4502419 biliverdin reductase B (flavin reductase (NADPH)) [Ho... 31 1.9
gi|4504505 hydroxysteroid (17-beta) dehydrogenase 4 [Homo sapiens] 30 3.2
gi|66773086 SH3-binding kinase 1 [Homo sapiens] 29 5.5
gi|126131104 fibrocystin isoform 2 [Homo sapiens] 28 9.3
gi|126131102 fibrocystin isoform 1 [Homo sapiens] 28 9.3
>gi|56118217 UDP-galactose-4-epimerase [Homo sapiens]
Length = 348
Score = 711 bits (1835), Expect = 0.0
Identities = 348/348 (100%), Positives = 348/348 (100%)
Query: 1 MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV 60
MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV
Sbjct: 1 MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV 60
Query: 61 EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK 120
EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK
Sbjct: 61 EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK 120
Query: 121 AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA 180
AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA
Sbjct: 121 AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA 180
Query: 181 VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD 240
VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD
Sbjct: 181 VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD 240
Query: 241 YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR 300
YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR
Sbjct: 241 YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR 300
Query: 301 EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA 348
EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA
Sbjct: 301 EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA 348
>gi|56237023 UDP-galactose-4-epimerase [Homo sapiens]
Length = 348
Score = 711 bits (1835), Expect = 0.0
Identities = 348/348 (100%), Positives = 348/348 (100%)
Query: 1 MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV 60
MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV
Sbjct: 1 MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV 60
Query: 61 EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK 120
EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK
Sbjct: 61 EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK 120
Query: 121 AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA 180
AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA
Sbjct: 121 AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA 180
Query: 181 VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD 240
VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD
Sbjct: 181 VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD 240
Query: 241 YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR 300
YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR
Sbjct: 241 YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR 300
Query: 301 EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA 348
EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA
Sbjct: 301 EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA 348
>gi|189083684 UDP-galactose-4-epimerase [Homo sapiens]
Length = 348
Score = 711 bits (1835), Expect = 0.0
Identities = 348/348 (100%), Positives = 348/348 (100%)
Query: 1 MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV 60
MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV
Sbjct: 1 MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV 60
Query: 61 EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK 120
EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK
Sbjct: 61 EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK 120
Query: 121 AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA 180
AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA
Sbjct: 121 AHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTWNA 180
Query: 181 VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD 240
VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD
Sbjct: 181 VLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVRD 240
Query: 241 YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR 300
YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR
Sbjct: 241 YIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARR 300
Query: 301 EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA 348
EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA
Sbjct: 301 EGDVAACYANPSLAQEELGWTAALGLDRMCEDLWRWQKQNPSGFGTQA 348
>gi|7657641 TDP-glucose 4,6-dehydratase [Homo sapiens]
Length = 350
Score = 84.7 bits (208), Expect = 1e-16
Identities = 74/287 (25%), Positives = 132/287 (45%), Gaps = 35/287 (12%)
Query: 2 AEKVLVTGGAGYIGSHTVLELLE--AGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGR- 58
A++VLVTGGAG+I SH ++ L+E Y+ + +D SL+ ++ ++ +
Sbjct: 17 AKRVLVTGGAGFIASHMIVSLVEDYPNYMIINLDKLDYC--------ASLKNLETISNKQ 68
Query: 59 SVEFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEI 118
+ +F + DI D ++ LF+ V+HFA V S + ++ VN+ GT L+
Sbjct: 69 NYKFIQGDICDSHFVKLLFETEKIDIVLHFAAQTHVDLSFVRAFEFTYVNVYGTHVLVSA 128
Query: 119 MKAHGVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTW 178
V+ ++ S+ VYG DE+ P TNPY SK E ++ + K +
Sbjct: 129 AHEARVEKFIYVSTDEVYGGSLDKEFDESSPKQP-TNPYASSKAAAECFVQSYWEQYK-F 186
Query: 179 NAVLLRYFNPTGAHASGCIGEDPQGIPNNLMP-YVSQVAIGRREALNVFGNDYDTEDGTG 237
V+ R N G H P ++P ++S + R+ ++ G
Sbjct: 187 PVVITRSSNVYGPHQ----------YPEKVIPKFISLLQHNRKCCIH--------GSGLQ 228
Query: 238 VRDYIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAM 284
R++++ D+ + + L+K K IYN+GT SV+Q+ + +
Sbjct: 229 TRNFLYATDVVEAFLTVLKKGKPG---EIYNIGTNFEMSVVQLAKEL 272
>gi|42516563 UDP-glucuronate decarboxylase 1 [Homo sapiens]
Length = 420
Score = 75.1 bits (183), Expect = 9e-14
Identities = 76/330 (23%), Positives = 141/330 (42%), Gaps = 42/330 (12%)
Query: 3 EKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEF 62
+++L+TGGAG++GSH +L+ G+ V+DNF + R V+ G
Sbjct: 89 KRILITGGAGFVGSHLTDKLMMDGHEVTVVDNFFTGRK---------RNVEHWIGH---- 135
Query: 63 EEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAH 122
E ++++ ++ L+ + + H A + + P+ + N GT+ +L + K
Sbjct: 136 ENFELINHDVVEPLYIEVD--QIYHLASPASPPNYMYNPIKTLKTNTIGTLNMLGLAKRV 193
Query: 123 GVKNLVFSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIE--EMIRDLCQADKTWNA 180
G + L+ +S++ VYG+P+ P E + G NP G + E + +C A
Sbjct: 194 GAR-LLLASTSEVYGDPEVHPQSEDY--WGHVNPIGPRACYDEGKRVAETMCYAYMKQEG 250
Query: 181 V---LLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTG 237
V + R FN G D + + N ++ Q G E L V+G+ G+
Sbjct: 251 VEVRVARIFNTFGPRMH---MNDGRVVSN----FILQALQG--EPLTVYGS------GSQ 295
Query: 238 VRDYIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVV 297
R + +V DL G +A + NLG +++L+ Q ++ G + +
Sbjct: 296 TRAFQYVSDLVNGLVALMNSNVSS----PVNLGNPEEHTILEFAQLIKNLVGSGSEIQFL 351
Query: 298 ARREGDVAACYANPSLAQEELGWTAALGLD 327
+ + D + A+ LGW + L+
Sbjct: 352 SEAQDDPQKRKPDIKKAKLMLGWEPVVPLE 381
>gi|239745448 PREDICTED: hypothetical protein XP_002343493 [Homo
sapiens]
Length = 422
Score = 47.4 bits (111), Expect = 2e-05
Identities = 41/155 (26%), Positives = 64/155 (41%), Gaps = 28/155 (18%)
Query: 3 EKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEF 62
+KVLVTGG GY+G L ++G +++D RR Q +F
Sbjct: 34 QKVLVTGGGGYLGFSLGSHLAKSGTSVILLDR---------------RRPQWELSPETKF 78
Query: 63 EEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAH 122
+ D+ D+ AL R F+ V H A G + +N+ GT ++++
Sbjct: 79 IQADVRDEEALYRAFEGVD--CVFHVASYGMSGAEKLQKEQIESINVGGTKLVIDVCVRR 136
Query: 123 GVKNLVFSSSATVY--GNP---------QYLPLDE 146
V L+++S+ V G P Y PLDE
Sbjct: 137 RVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDE 171
>gi|116268111 short chain dehydrogenase/reductase family 42E, member
1 [Homo sapiens]
Length = 393
Score = 46.6 bits (109), Expect = 3e-05
Identities = 65/276 (23%), Positives = 108/276 (39%), Gaps = 55/276 (19%)
Query: 3 EKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEF 62
E VL+TGG+GY G L + G ++ D A ++PE ++ +Q
Sbjct: 9 ESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPA----QTIPEGIKFIQG-------- 56
Query: 63 EEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAH 122
DI +++ F+ V H A G VN+ GT +L++ +
Sbjct: 57 ---DIRHLSDVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRR 113
Query: 123 GVKNLVFSSSATVYGNPQ----------YLPLDEAHPTGGCTNPYGKSKFFIEEMIRD-- 170
V LV++S+ V Q YLPL HP + Y ++K E+ + +
Sbjct: 114 RVPRLVYTSTFNVIFGGQVIRNGDESLPYLPL-HLHP-----DHYSRTKSIAEQKVLEAN 167
Query: 171 ---LCQADKTWNAVLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFG 227
L + D LR P G + G + + +P VS + G + V+G
Sbjct: 168 ATPLDRGDGVLRTCALR---PAGIYGPG----EQRHLPR----IVSYIEKGLFKF--VYG 214
Query: 228 NDYDTEDGTGVRDYIHVVDLAKGHIAALRKLKEQCG 263
D + +++HV +L + HI A L+ G
Sbjct: 215 ------DPRSLVEFVHVDNLVQAHILASEALRADKG 244
>gi|4504031 GDP-mannose 4,6-dehydratase [Homo sapiens]
Length = 372
Score = 46.6 bits (109), Expect = 3e-05
Identities = 67/308 (21%), Positives = 129/308 (41%), Gaps = 31/308 (10%)
Query: 6 LVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFEEM 65
L+TG G GS+ LLE GY I ++F G + + Q +++
Sbjct: 27 LITGITGQDGSYLAEFLLEKGYEVHGIVRRSSSF-NTGRIEHLYKNPQAHIEGNMKLHYG 85
Query: 66 DILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHGVK 125
D+ D L ++ + + + V S V+ GT++LL+ +K G+
Sbjct: 86 DLTDSTCLVKIINEVKPTEIYNLGAQSHVKISFDLAEYTADVDGVGTLRLLDAVKTCGLI 145
Query: 126 NLV---FSSSATVYGNPQYLPLDEAHPTGGCTNPYGKSKFFIEEMIRDLCQADKTW--NA 180
N V +S++ +YG Q +P E P +PYG +K + ++ + +A + N
Sbjct: 146 NSVKFYQASTSELYGKVQEIPQKETTPFYP-RSPYGAAKLYAYWIVVNFREAYNLFAVNG 204
Query: 181 VLLRYFNP-TGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTGVR 239
+L + +P GA+ + + V+++ +G+ E ++ D R
Sbjct: 205 ILFNHESPRRGANF----------VTRKISRSVAKIYLGQLECFSLGNLD-------AKR 247
Query: 240 DYIHVVDLAKGHIAALRKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVAR 299
D+ H AK ++ A+ + + + + TG +SV + V+ GK I ++ +
Sbjct: 248 DWGH----AKDYVEAMWLMLQNDEPEDFVIATGEVHSVREFVEKSFLHIGKTIVWE--GK 301
Query: 300 REGDVAAC 307
E +V C
Sbjct: 302 NENEVGRC 309
>gi|239756515 PREDICTED: similar to Putative 3-beta-HSD family
protein ENSP00000330812 [Homo sapiens]
Length = 422
Score = 45.4 bits (106), Expect = 7e-05
Identities = 40/155 (25%), Positives = 63/155 (40%), Gaps = 28/155 (18%)
Query: 3 EKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEF 62
+KVLVTGG GY+G L ++G +++D RR Q +F
Sbjct: 34 QKVLVTGGGGYLGFSLGSHLAKSGTSVILLDR---------------RRPQWELSPETKF 78
Query: 63 EEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAH 122
+ D+ D+ AL F+ V H A G + +N+ GT ++++
Sbjct: 79 IQADVRDEEALYHAFEGVD--CVFHVASYGMSGAEKLQKEQIESINVGGTKLVIDVCVRR 136
Query: 123 GVKNLVFSSSATVY--GNP---------QYLPLDE 146
V L+++S+ V G P Y PLDE
Sbjct: 137 RVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDE 171
>gi|239751020 PREDICTED: hypothetical protein XP_002347673 [Homo
sapiens]
Length = 422
Score = 45.4 bits (106), Expect = 7e-05
Identities = 40/155 (25%), Positives = 63/155 (40%), Gaps = 28/155 (18%)
Query: 3 EKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEF 62
+KVLVTGG GY+G L ++G +++D RR Q +F
Sbjct: 34 QKVLVTGGGGYLGFSLGSHLAKSGTSVILLDR---------------RRPQWELSPETKF 78
Query: 63 EEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAH 122
+ D+ D+ AL F+ V H A G + +N+ GT ++++
Sbjct: 79 IQADVRDEEALYHAFEGVD--CVFHVASYGMSGAEKLQKEQIESINVGGTKLVIDVCVRR 136
Query: 123 GVKNLVFSSSATVY--GNP---------QYLPLDE 146
V L+++S+ V G P Y PLDE
Sbjct: 137 RVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDE 171
>gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo
sapiens]
Length = 373
Score = 45.4 bits (106), Expect = 7e-05
Identities = 70/264 (26%), Positives = 104/264 (39%), Gaps = 53/264 (20%)
Query: 2 AEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVE 61
A++ V GG+G++G H V +LL GY V D + G P+ V
Sbjct: 37 AKRCTVIGGSGFLGQHMVEQLLARGYAVNVFD-----IQQGFDNPQ------------VR 79
Query: 62 FEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKA 121
F D+ + L K + V H A S K L +YRVN GT ++E K
Sbjct: 80 FFLGDLCSRQDLYPALKGVN--TVFHCASPPP--SSNNKEL-FYRVNYIGTKNVIETCKE 134
Query: 122 HGVKNLVFSSSATVYGNPQYLPLDEAHPTGGC------TNPYGKSKFFIEEMIRDLCQAD 175
GV+ L+ +SSA+V + +D + T + Y ++K E + +
Sbjct: 135 AGVQKLILTSSASVI----FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPE 190
Query: 176 KTWNAVLLRYFNPTGAHASGCIG-EDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTED 234
K F T G G DPQ L+P + + A + V GN + D
Sbjct: 191 KN--------FLTTAIRPHGIFGPRDPQ-----LVPILIEAARNGKMKF-VIGNGKNLVD 236
Query: 235 GTGVRDYIHVVDLAKGHIAALRKL 258
T V + +H GHI A +L
Sbjct: 237 FTFVENVVH------GHILAAEQL 254
>gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo
sapiens]
Length = 373
Score = 45.4 bits (106), Expect = 7e-05
Identities = 70/264 (26%), Positives = 104/264 (39%), Gaps = 53/264 (20%)
Query: 2 AEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVE 61
A++ V GG+G++G H V +LL GY V D + G P+ V
Sbjct: 37 AKRCTVIGGSGFLGQHMVEQLLARGYAVNVFD-----IQQGFDNPQ------------VR 79
Query: 62 FEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKA 121
F D+ + L K + V H A S K L +YRVN GT ++E K
Sbjct: 80 FFLGDLCSRQDLYPALKGVN--TVFHCASPPP--SSNNKEL-FYRVNYIGTKNVIETCKE 134
Query: 122 HGVKNLVFSSSATVYGNPQYLPLDEAHPTGGC------TNPYGKSKFFIEEMIRDLCQAD 175
GV+ L+ +SSA+V + +D + T + Y ++K E + +
Sbjct: 135 AGVQKLILTSSASVI----FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPE 190
Query: 176 KTWNAVLLRYFNPTGAHASGCIG-EDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTED 234
K F T G G DPQ L+P + + A + V GN + D
Sbjct: 191 KN--------FLTTAIRPHGIFGPRDPQ-----LVPILIEAARNGKMKF-VIGNGKNLVD 236
Query: 235 GTGVRDYIHVVDLAKGHIAALRKL 258
T V + +H GHI A +L
Sbjct: 237 FTFVENVVH------GHILAAEQL 254
>gi|19923621 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
steroid delta-isomerase 7 isoform a [Homo sapiens]
Length = 369
Score = 40.8 bits (94), Expect = 0.002
Identities = 50/163 (30%), Positives = 67/163 (41%), Gaps = 35/163 (21%)
Query: 6 LVTGGAGYIGSHTVLELLE----AGYLPVVIDNFHNAFRGGGSLPESLR----RVQELTG 57
LVTGG G++G H V LL+ G L V + G E L+ RV + G
Sbjct: 13 LVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHL-------GPWLEELKTGPVRVTAIQG 65
Query: 58 RSVEFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAV-GESVQKPLDYYRVNLTGTIQLL 116
+ E+ GA VIH AGL V G + P + VN+ GT ++
Sbjct: 66 DVTQAHEVAAAVAGA----------HVVIHTAGLVDVFGRA--SPKTIHEVNVQGTRNVI 113
Query: 117 EIMKAHGVKNLVFSSSATVYGNPQYLPLDEAHP--TGGCTNPY 157
E G + LV++SS V G P + HP G PY
Sbjct: 114 EACVQTGTRFLVYTSSMEVVG-----PNTKGHPFYRGNEDTPY 151
>gi|218563686 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
steroid delta-isomerase 7 isoform b [Homo sapiens]
Length = 196
Score = 40.8 bits (94), Expect = 0.002
Identities = 50/163 (30%), Positives = 67/163 (41%), Gaps = 35/163 (21%)
Query: 6 LVTGGAGYIGSHTVLELLE----AGYLPVVIDNFHNAFRGGGSLPESLR----RVQELTG 57
LVTGG G++G H V LL+ G L V + G E L+ RV + G
Sbjct: 13 LVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHL-------GPWLEELKTGPVRVTAIQG 65
Query: 58 RSVEFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAV-GESVQKPLDYYRVNLTGTIQLL 116
+ E+ GA VIH AGL V G + P + VN+ GT ++
Sbjct: 66 DVTQAHEVAAAVAGA----------HVVIHTAGLVDVFGRA--SPKTIHEVNVQGTRNVI 113
Query: 117 EIMKAHGVKNLVFSSSATVYGNPQYLPLDEAHP--TGGCTNPY 157
E G + LV++SS V G P + HP G PY
Sbjct: 114 EACVQTGTRFLVYTSSMEVVG-----PNTKGHPFYRGNEDTPY 151
>gi|218563684 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
steroid delta-isomerase 7 isoform b [Homo sapiens]
Length = 196
Score = 40.8 bits (94), Expect = 0.002
Identities = 50/163 (30%), Positives = 67/163 (41%), Gaps = 35/163 (21%)
Query: 6 LVTGGAGYIGSHTVLELLE----AGYLPVVIDNFHNAFRGGGSLPESLR----RVQELTG 57
LVTGG G++G H V LL+ G L V + G E L+ RV + G
Sbjct: 13 LVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHL-------GPWLEELKTGPVRVTAIQG 65
Query: 58 RSVEFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAV-GESVQKPLDYYRVNLTGTIQLL 116
+ E+ GA VIH AGL V G + P + VN+ GT ++
Sbjct: 66 DVTQAHEVAAAVAGA----------HVVIHTAGLVDVFGRA--SPKTIHEVNVQGTRNVI 113
Query: 117 EIMKAHGVKNLVFSSSATVYGNPQYLPLDEAHP--TGGCTNPY 157
E G + LV++SS V G P + HP G PY
Sbjct: 114 EACVQTGTRFLVYTSSMEVVG-----PNTKGHPFYRGNEDTPY 151
>gi|4504509 3 beta-hydroxysteroid dehydrogenase 2 [Homo sapiens]
Length = 372
Score = 40.0 bits (92), Expect = 0.003
Identities = 55/178 (30%), Positives = 72/178 (40%), Gaps = 23/178 (12%)
Query: 1 MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV 60
M LVTG G +G V L+E L I AFR L E ++Q T +V
Sbjct: 1 MGWSCLVTGAGGLLGQRIVRLLVEEKELKE-IRALDKAFRP--ELREEFSKLQNRTKLTV 57
Query: 61 EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK 120
E DILD+ L+R + S VIH A + V + VN+ GT LLE
Sbjct: 58 L--EGDILDEPFLKRACQDVS--VVIHTACIIDVFGVTHRE-SIMNVNVKGTQLLLEACV 112
Query: 121 AHGVKNLVFSSSATVYGNPQYL----------PLDEAHPTGGCTNPYGKSKFFIEEMI 168
V +++SS V G Y PL+ PT PY SK E+ +
Sbjct: 113 QASVPVFIYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPT-----PYPYSKKLAEKAV 165
>gi|4507709 tissue specific transplantation antigen P35B [Homo
sapiens]
Length = 321
Score = 40.0 bits (92), Expect = 0.003
Identities = 65/263 (24%), Positives = 104/263 (39%), Gaps = 41/263 (15%)
Query: 4 KVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFE 63
++LVTGG+G +G VV D G LP V +
Sbjct: 9 RILVTGGSGLVGK---------AIQKVVAD--------GAGLPGE-------DWVFVSSK 44
Query: 64 EMDILDQGALQRLFKKYSFMAVIHFAGL-KAVGESVQKPLDYYRVNLTGTIQLLEIMKAH 122
+ D+ D + LF+K VIH A + + +++ LD++R N+ +L
Sbjct: 45 DADLTDTAQTRALFEKVQPTHVIHLAAMVGGLFRNIKYNLDFWRKNVHMNDNVLHSAFEV 104
Query: 123 GVKNLVFSSSATVYGNPQYLPLDEA----HPTGGCTNPYGKSKFFIEEMIRDLCQA-DKT 177
G + +V S ++ + P+DE P Y +K I+ R Q T
Sbjct: 105 GARKVVSCLSTCIFPDKTTYPIDETMIHNGPPHNSNFGYSYAKRMIDVQNRAYFQQYGCT 164
Query: 178 WNAVLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTEDGTG 237
+ AV+ N G H + I ED +P + + +A AL V+G G
Sbjct: 165 FTAVIPT--NVFGPHDNFNI-EDGHVLPG--LIHKVHLAKSSGSALTVWGT------GNP 213
Query: 238 VRDYIHVVDLAKGHIAALRKLKE 260
R +I+ +DLA+ I LR+ E
Sbjct: 214 RRQFIYSLDLAQLFIWVLREYNE 236
>gi|4504507 3 beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]
Length = 373
Score = 37.4 bits (85), Expect = 0.020
Identities = 50/173 (28%), Positives = 71/173 (41%), Gaps = 23/173 (13%)
Query: 6 LVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFEEM 65
LVTG G++G + L++ L I AF G L E ++Q T +V E
Sbjct: 7 LVTGAGGFLGQRIIRLLVKEKELKE-IRVLDKAF--GPELREEFSKLQNKTKLTVL--EG 61
Query: 66 DILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHGVK 125
DILD+ L+R + S +IH A + V + VN+ GT LLE V
Sbjct: 62 DILDEPFLKRACQDVS--VIIHTACIIDVFGVTHRE-SIMNVNVKGTQLLLEACVQASVP 118
Query: 126 NLVFSSSATVYGNPQYL----------PLDEAHPTGGCTNPYGKSKFFIEEMI 168
+++SS V G Y PL+ P PY SK E+ +
Sbjct: 119 VFIYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPA-----PYPHSKKLAEKAV 166
>gi|33519455 methionine adenosyltransferase II, beta isoform 2 [Homo
sapiens]
Length = 323
Score = 32.3 bits (72), Expect = 0.65
Identities = 39/166 (23%), Positives = 66/166 (39%), Gaps = 26/166 (15%)
Query: 4 KVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFE 63
+VLVTG G +G E + +N+H G RR + +FE
Sbjct: 19 RVLVTGATGLLGRAVHKEFQQ--------NNWHAVGCG-------FRRARP------KFE 57
Query: 64 EMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHG 123
++++LD A+ + + ++H A + +P ++N+ + L + A G
Sbjct: 58 QVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAVG 117
Query: 124 VKNLVFSSSATVYG-NPQYLPLDEAHPTGGCTNPYGKSKFFIEEMI 168
+ SS G NP Y D P N YGK+K E+ +
Sbjct: 118 AFLIYISSDYVFDGTNPPYREEDIPAP----LNLYGKTKLDGEKAV 159
>gi|11034825 methionine adenosyltransferase II, beta isoform 1 [Homo
sapiens]
Length = 334
Score = 32.3 bits (72), Expect = 0.65
Identities = 39/166 (23%), Positives = 66/166 (39%), Gaps = 26/166 (15%)
Query: 4 KVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFE 63
+VLVTG G +G E + +N+H G RR + +FE
Sbjct: 30 RVLVTGATGLLGRAVHKEFQQ--------NNWHAVGCG-------FRRARP------KFE 68
Query: 64 EMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHG 123
++++LD A+ + + ++H A + +P ++N+ + L + A G
Sbjct: 69 QVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAVG 128
Query: 124 VKNLVFSSSATVYG-NPQYLPLDEAHPTGGCTNPYGKSKFFIEEMI 168
+ SS G NP Y D P N YGK+K E+ +
Sbjct: 129 AFLIYISSDYVFDGTNPPYREEDIPAP----LNLYGKTKLDGEKAV 170
>gi|4502419 biliverdin reductase B (flavin reductase (NADPH)) [Homo
sapiens]
Length = 206
Score = 30.8 bits (68), Expect = 1.9
Identities = 35/142 (24%), Positives = 56/142 (39%), Gaps = 24/142 (16%)
Query: 3 EKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLP-ESLRRVQELTGRSVE 61
+K+ + G G G T+ + ++AGY V+ R LP E R + G ++
Sbjct: 4 KKIAIFGATGQTGLTTLAQAVQAGYEVTVL------VRDSSRLPSEGPRPAHVVVGDVLQ 57
Query: 62 FEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKA 121
++D G AVI G + L V G ++ MKA
Sbjct: 58 AADVDKTVAGQ----------DAVIVLLGTR-------NDLSPTTVMSEGARNIVAAMKA 100
Query: 122 HGVKNLVFSSSATVYGNPQYLP 143
HGV +V +SA + +P +P
Sbjct: 101 HGVDKVVACTSAFLLWDPTKVP 122
>gi|4504505 hydroxysteroid (17-beta) dehydrogenase 4 [Homo sapiens]
Length = 736
Score = 30.0 bits (66), Expect = 3.2
Identities = 39/150 (26%), Positives = 68/150 (45%), Gaps = 19/150 (12%)
Query: 5 VLVTGGAGYIGSHTVLELLEAGYLPVVID---NFHNAFRGGGSLPESLRRVQELTGRSV- 60
VLVTG +G L E G L VV D +F +G + + + ++ G++V
Sbjct: 12 VLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVA 71
Query: 61 ---EFEEMDILDQGALQRLFKKYSFMAVIHFAGL---KAVGESVQKPLD-YYRVNLTGTI 113
EE + + + AL + V++ AG+ ++ + D +RV+L G+
Sbjct: 72 NYDSVEEGEKVVKTALDAFGR---IDVVVNNAGILRDRSFARISDEDWDIIHRVHLRGSF 128
Query: 114 QLL----EIMKAHGVKNLVFSSSAT-VYGN 138
Q+ E MK ++ +SSA+ +YGN
Sbjct: 129 QVTRAAWEHMKKQKYGRIIMTSSASGIYGN 158
>gi|66773086 SH3-binding kinase 1 [Homo sapiens]
Length = 424
Score = 29.3 bits (64), Expect = 5.5
Identities = 22/90 (24%), Positives = 36/90 (40%), Gaps = 6/90 (6%)
Query: 258 LKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARREGDVAACYANPSLAQEE 317
+ + GCR+ + Y+ ++ QA +A G + V G + C +
Sbjct: 197 MTRRVGCRVKRVSGTIPYTAPEVCQA-GRADGLAVDTGVDVWAFGVLIFCVLTGNFP--- 252
Query: 318 LGWTAALGLDRMCEDLWRWQKQNPSGFGTQ 347
W AA G D E+ RWQ+ G +Q
Sbjct: 253 --WEAASGADAFFEEFVRWQRGRLPGLPSQ 280
>gi|126131104 fibrocystin isoform 2 [Homo sapiens]
Length = 3396
Score = 28.5 bits (62), Expect = 9.3
Identities = 20/95 (21%), Positives = 42/95 (44%), Gaps = 6/95 (6%)
Query: 164 IEEMIRDLCQADKTWNAVLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREAL 223
IEE++ C+ + W+ +LLR G S G+ + + P+ + ++ R+
Sbjct: 539 IEELLAVKCKLEPLWSNILLRLGFERGPEVSNSDGD----LTSGTEPFCGRFSL--RQPR 592
Query: 224 NVFGNDYDTEDGTGVRDYIHVVDLAKGHIAALRKL 258
++ + G + Y H+ KGH+ + K+
Sbjct: 593 HLVLTPPAAQKGYRLDQYTHLCLAYKGHMNKILKM 627
>gi|126131102 fibrocystin isoform 1 [Homo sapiens]
Length = 4074
Score = 28.5 bits (62), Expect = 9.3
Identities = 20/95 (21%), Positives = 42/95 (44%), Gaps = 6/95 (6%)
Query: 164 IEEMIRDLCQADKTWNAVLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREAL 223
IEE++ C+ + W+ +LLR G S G+ + + P+ + ++ R+
Sbjct: 539 IEELLAVKCKLEPLWSNILLRLGFERGPEVSNSDGD----LTSGTEPFCGRFSL--RQPR 592
Query: 224 NVFGNDYDTEDGTGVRDYIHVVDLAKGHIAALRKL 258
++ + G + Y H+ KGH+ + K+
Sbjct: 593 HLVLTPPAAQKGYRLDQYTHLCLAYKGHMNKILKM 627
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,573,353
Number of Sequences: 37866
Number of extensions: 597903
Number of successful extensions: 1076
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1054
Number of HSP's gapped (non-prelim): 29
length of query: 348
length of database: 18,247,518
effective HSP length: 103
effective length of query: 245
effective length of database: 14,347,320
effective search space: 3515093400
effective search space used: 3515093400
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.