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Search of human proteins with 55953123
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55953123 RWD domain containing 1 isoform a [Homo sapiens]
(243 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55953123 RWD domain containing 1 isoform a [Homo sapiens] 482 e-136
gi|55953127 RWD domain containing 1 isoform b [Homo sapiens] 294 4e-80
gi|55953125 RWD domain containing 1 isoform b [Homo sapiens] 294 4e-80
gi|65287717 eukaryotic translation initiation factor 2 alpha kin... 57 2e-08
gi|34878787 ring finger protein 25 [Homo sapiens] 49 4e-06
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 48 7e-06
gi|116256479 RWD domain containing 4A [Homo sapiens] 47 1e-05
gi|225579095 S-phase cyclin A-associated protein in the ER isofo... 44 1e-04
gi|225579092 S-phase cyclin A-associated protein in the ER isofo... 44 1e-04
gi|118150660 erythropoietin 4 immediate early response [Homo sap... 42 4e-04
gi|8923819 Impact homolog [Homo sapiens] 40 0.002
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 39 0.004
gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo ... 39 0.005
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo... 39 0.005
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo... 39 0.005
gi|169161522 PREDICTED: similar to cell division cycle 2-like 1 ... 38 0.009
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo... 38 0.009
gi|38569484 kinesin family member 21A [Homo sapiens] 38 0.009
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 38 0.009
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 37 0.012
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 37 0.012
gi|239747195 PREDICTED: similar to PITSLRE protein kinase beta S... 37 0.012
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 37 0.012
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 37 0.012
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] 37 0.012
gi|8922712 septin 11 [Homo sapiens] 37 0.016
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 37 0.020
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof... 37 0.020
gi|21396500 HIRA interacting protein 3 [Homo sapiens] 37 0.020
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi... 37 0.020
>gi|55953123 RWD domain containing 1 isoform a [Homo sapiens]
Length = 243
Score = 482 bits (1241), Expect = e-136
Identities = 243/243 (100%), Positives = 243/243 (100%)
Query: 1 MTDYGEEQRNELEALESIYPDSFTVLSENPPSFTITVTSEAGENDETVQTTLKFTYSEKY 60
MTDYGEEQRNELEALESIYPDSFTVLSENPPSFTITVTSEAGENDETVQTTLKFTYSEKY
Sbjct: 1 MTDYGEEQRNELEALESIYPDSFTVLSENPPSFTITVTSEAGENDETVQTTLKFTYSEKY 60
Query: 61 PDEAPLYEIFSQENLEDNDVSDILKLLALQAEENLGMVMIFTLVTAVQEKLNEIVDQIKT 120
PDEAPLYEIFSQENLEDNDVSDILKLLALQAEENLGMVMIFTLVTAVQEKLNEIVDQIKT
Sbjct: 61 PDEAPLYEIFSQENLEDNDVSDILKLLALQAEENLGMVMIFTLVTAVQEKLNEIVDQIKT 120
Query: 121 RREEEKKQKEKEAEEAEKQLFHGTPVTIENFLNWKAKFDAELLEIKKKRMKEEEQAGKNK 180
RREEEKKQKEKEAEEAEKQLFHGTPVTIENFLNWKAKFDAELLEIKKKRMKEEEQAGKNK
Sbjct: 121 RREEEKKQKEKEAEEAEKQLFHGTPVTIENFLNWKAKFDAELLEIKKKRMKEEEQAGKNK 180
Query: 181 LSGKQLFETDHNLDTSDIQFLEDAGNNVEVDESLFQEMDDLELEDDEDDPDYNPADPESD 240
LSGKQLFETDHNLDTSDIQFLEDAGNNVEVDESLFQEMDDLELEDDEDDPDYNPADPESD
Sbjct: 181 LSGKQLFETDHNLDTSDIQFLEDAGNNVEVDESLFQEMDDLELEDDEDDPDYNPADPESD 240
Query: 241 SAD 243
SAD
Sbjct: 241 SAD 243
>gi|55953127 RWD domain containing 1 isoform b [Homo sapiens]
Length = 147
Score = 294 bits (753), Expect = 4e-80
Identities = 147/147 (100%), Positives = 147/147 (100%)
Query: 97 MVMIFTLVTAVQEKLNEIVDQIKTRREEEKKQKEKEAEEAEKQLFHGTPVTIENFLNWKA 156
MVMIFTLVTAVQEKLNEIVDQIKTRREEEKKQKEKEAEEAEKQLFHGTPVTIENFLNWKA
Sbjct: 1 MVMIFTLVTAVQEKLNEIVDQIKTRREEEKKQKEKEAEEAEKQLFHGTPVTIENFLNWKA 60
Query: 157 KFDAELLEIKKKRMKEEEQAGKNKLSGKQLFETDHNLDTSDIQFLEDAGNNVEVDESLFQ 216
KFDAELLEIKKKRMKEEEQAGKNKLSGKQLFETDHNLDTSDIQFLEDAGNNVEVDESLFQ
Sbjct: 61 KFDAELLEIKKKRMKEEEQAGKNKLSGKQLFETDHNLDTSDIQFLEDAGNNVEVDESLFQ 120
Query: 217 EMDDLELEDDEDDPDYNPADPESDSAD 243
EMDDLELEDDEDDPDYNPADPESDSAD
Sbjct: 121 EMDDLELEDDEDDPDYNPADPESDSAD 147
>gi|55953125 RWD domain containing 1 isoform b [Homo sapiens]
Length = 147
Score = 294 bits (753), Expect = 4e-80
Identities = 147/147 (100%), Positives = 147/147 (100%)
Query: 97 MVMIFTLVTAVQEKLNEIVDQIKTRREEEKKQKEKEAEEAEKQLFHGTPVTIENFLNWKA 156
MVMIFTLVTAVQEKLNEIVDQIKTRREEEKKQKEKEAEEAEKQLFHGTPVTIENFLNWKA
Sbjct: 1 MVMIFTLVTAVQEKLNEIVDQIKTRREEEKKQKEKEAEEAEKQLFHGTPVTIENFLNWKA 60
Query: 157 KFDAELLEIKKKRMKEEEQAGKNKLSGKQLFETDHNLDTSDIQFLEDAGNNVEVDESLFQ 216
KFDAELLEIKKKRMKEEEQAGKNKLSGKQLFETDHNLDTSDIQFLEDAGNNVEVDESLFQ
Sbjct: 61 KFDAELLEIKKKRMKEEEQAGKNKLSGKQLFETDHNLDTSDIQFLEDAGNNVEVDESLFQ 120
Query: 217 EMDDLELEDDEDDPDYNPADPESDSAD 243
EMDDLELEDDEDDPDYNPADPESDSAD
Sbjct: 121 EMDDLELEDDEDDPDYNPADPESDSAD 147
>gi|65287717 eukaryotic translation initiation factor 2 alpha kinase
4 [Homo sapiens]
Length = 1649
Score = 56.6 bits (135), Expect = 2e-08
Identities = 54/204 (26%), Positives = 91/204 (44%), Gaps = 27/204 (13%)
Query: 4 YGEEQRNELEALESIYPDSFTVLS-------ENPPSFTITVTSEAGENDET-VQTTLKFT 55
Y + Q +EL+ALE+IY F L + PP + + + +E V+ L+
Sbjct: 19 YPQRQDHELQALEAIYGADFQDLRPDACGPVKEPPEINLVLYPQGLTGEEVYVKVDLRVK 78
Query: 56 YSEKYPDEAPLYEIFSQENLEDNDVSDILKLLALQAEENLGMVMIFTLVTAVQEKLNE-- 113
YPD P E+ + + L + V+ + L A+++ G VMIF L VQ L+E
Sbjct: 79 CPPTYPDVVPEIELKNAKGLSNESVNLLKSRLEELAKKHCGEVMIFELAYHVQSFLSEHN 138
Query: 114 ------IVDQIKTRREEEKKQKEKEAEEAEKQLFHGTPVTIENFLNWKAKFDAELLEIKK 167
+++ RR +E++Q+ EA+ E+Q L+ + E+ E KK
Sbjct: 139 KPPPKSFHEEMLERRAQEEQQRLLEAKRKEEQ-------EQREILHEIQRRKEEIKEEKK 191
Query: 168 KRMKEEEQAGKNKLSGKQLFETDH 191
++ E A + +L L DH
Sbjct: 192 RK----EMAKQERLEIASLSNQDH 211
>gi|34878787 ring finger protein 25 [Homo sapiens]
Length = 459
Score = 48.9 bits (115), Expect = 4e-06
Identities = 34/110 (30%), Positives = 52/110 (47%), Gaps = 6/110 (5%)
Query: 10 NELEALESIYPDSFTVLSEN----PPSFTITVTSEAGENDET--VQTTLKFTYSEKYPDE 63
+E+E LESIY D V+ N P IT+ E+ ++ V TL +YP E
Sbjct: 18 SEVEVLESIYLDELQVIKGNGRTSPWEIYITLHPATAEDQDSQYVCFTLVLQVPAEYPHE 77
Query: 64 APLYEIFSQENLEDNDVSDILKLLALQAEENLGMVMIFTLVTAVQEKLNE 113
P I + L D + IL++L A+ LG M++ L+ +E L +
Sbjct: 78 VPQISIRNPRGLSDEQIHTILQVLGHVAKAGLGTAMLYELIEKGKEILTD 127
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 48.1 bits (113), Expect = 7e-06
Identities = 55/195 (28%), Positives = 84/195 (43%), Gaps = 25/195 (12%)
Query: 2 TDYGEEQRNELEALESIYPDSFTVLSENPPSFTITVTSEAGENDETVQTTLKFTYSEKYP 61
T G+ E E LES +P+ +VLS + S + +S G Q + + +P
Sbjct: 259 TPQGKNMTPESEVLES-FPEEDSVLSHSSLSSPSSTSSPEGPPAPPKQ----HSSTSPFP 313
Query: 62 DEAPLYEI---FSQENLEDNDVSDILKLLALQAEENLGMVMIFTLVTAVQEKLNEIVDQI 118
PL I F + + E N KL + +E LG + +EKL E +
Sbjct: 314 TSTPLRRITKKFVKGSTEKN------KLRLQRDQERLGKQLKLRAEREEKEKLKE---EA 364
Query: 119 KTRREEEKKQKEKEAEEAEKQLFHGTPVTIENFLNWKAKFDAELLEIKKKRMKEEEQAGK 178
K +EE KK+KE+E E EK+ K AE +K++R KE ++A +
Sbjct: 365 KRAKEEAKKKKEEEKELKEKER--------REKREKDEKEKAEKQRLKEERRKERQEALE 416
Query: 179 NKLSGKQLFETDHNL 193
KL K+ E + L
Sbjct: 417 AKLEEKRKKEEEKRL 431
>gi|116256479 RWD domain containing 4A [Homo sapiens]
Length = 188
Score = 47.4 bits (111), Expect = 1e-05
Identities = 37/154 (24%), Positives = 63/154 (40%), Gaps = 24/154 (15%)
Query: 6 EEQRNELEALESIYPDSFTVLSENPPSFTITVTSEAGENDETVQTTLKFTYSEKYPDEAP 65
E+Q ELEAL SIY + +P SF + GEN + ++ +++E YP P
Sbjct: 5 EDQEMELEALRSIYEGDESFRELSPVSFQYRI----GENGDPKAFLIEISWTETYPQTPP 60
Query: 66 LYEI--FSQENLEDNDVSDILKLLALQAEENLGMVMIFTLVTAVQEKLNEI--------- 114
+ + F + IL L E NLG M +TL ++ +
Sbjct: 61 ILSMNAFFNNTISSAVKQSILAKLQEAVEANLGTAMTYTLFEYAKDNKEQFMENHNPINS 120
Query: 115 ---------VDQIKTRREEEKKQKEKEAEEAEKQ 139
++ T +KK K+++ +A+K+
Sbjct: 121 ATSISNIISIETPNTAPSSKKKDKKEQLSKAQKR 154
>gi|225579095 S-phase cyclin A-associated protein in the ER isoform
b [Homo sapiens]
Length = 1154
Score = 44.3 bits (103), Expect = 1e-04
Identities = 33/166 (19%), Positives = 85/166 (51%), Gaps = 7/166 (4%)
Query: 59 KYPDEAPLYEIFSQENLEDNDVSDILKLLALQAEENLGMVMIFTLVTAVQEKLNEIVDQI 118
++ E L I + E+ V++I + L+A+ V+ + + +++LNE+ ++
Sbjct: 356 EFKREVQLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVL--SKLKEYEQRLNELQEE- 412
Query: 119 KTRREEEKKQKEKEAEEAEKQLFHGTPVTIENFLNWKAKFDAELLEIKKKRMKEEEQAGK 178
+ RR+EEK+ +++ +E ++ L +E L + + +A + + ++++ K E A +
Sbjct: 413 RQRRQEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEKAREDAAR 472
Query: 179 NKLSGKQLFETDHNLDTSDIQFLEDAGNNVEV--DESLFQEMDDLE 222
+ ++ E L + + +E+ +++ DES+ + M+ +E
Sbjct: 473 ERARDRE--ERLAALTAAQQEAMEELQKKIQLKHDESIRRHMEQIE 516
>gi|225579092 S-phase cyclin A-associated protein in the ER isoform
a [Homo sapiens]
Length = 1400
Score = 44.3 bits (103), Expect = 1e-04
Identities = 33/166 (19%), Positives = 85/166 (51%), Gaps = 7/166 (4%)
Query: 59 KYPDEAPLYEIFSQENLEDNDVSDILKLLALQAEENLGMVMIFTLVTAVQEKLNEIVDQI 118
++ E L I + E+ V++I + L+A+ V+ + + +++LNE+ ++
Sbjct: 602 EFKREVQLQAIVKKAQEEEAKVNEIAFINTLEAQNKRHDVL--SKLKEYEQRLNELQEE- 658
Query: 119 KTRREEEKKQKEKEAEEAEKQLFHGTPVTIENFLNWKAKFDAELLEIKKKRMKEEEQAGK 178
+ RR+EEK+ +++ +E ++ L +E L + + +A + + ++++ K E A +
Sbjct: 659 RQRRQEEKQARDEAVQERKRALEAERQARVEELLMKRKEQEARIEQQRQEKEKAREDAAR 718
Query: 179 NKLSGKQLFETDHNLDTSDIQFLEDAGNNVEV--DESLFQEMDDLE 222
+ ++ E L + + +E+ +++ DES+ + M+ +E
Sbjct: 719 ERARDRE--ERLAALTAAQQEAMEELQKKIQLKHDESIRRHMEQIE 762
>gi|118150660 erythropoietin 4 immediate early response [Homo
sapiens]
Length = 426
Score = 42.4 bits (98), Expect = 4e-04
Identities = 36/120 (30%), Positives = 62/120 (51%), Gaps = 20/120 (16%)
Query: 123 EEEKKQKEKEAEEAEKQLFHG---------TPVTIENFLNWKAKFDAE---LLEIKKKRM 170
+++KK++EKE E + + L T +T+E+FL WK + E LE +R
Sbjct: 218 KKDKKKEEKEDEISLEDLIERERSALGPNVTKITLESFLAWKKRKRQEKIDKLEQDMERR 277
Query: 171 KEEEQAGKN-KLSGKQLFE------TDHNLDTSDIQFLEDAGNNVEVDESLFQEMDDLEL 223
K + +AGK +SG+++FE D + + D ++ + G + EVD+S+ DL L
Sbjct: 278 KADFKAGKALVISGREVFEFRPELVNDDDEEADDTRYTQGTGGD-EVDDSVSVNDIDLSL 336
>gi|8923819 Impact homolog [Homo sapiens]
Length = 320
Score = 39.7 bits (91), Expect = 0.002
Identities = 36/143 (25%), Positives = 73/143 (51%), Gaps = 11/143 (7%)
Query: 3 DYGEEQRN--ELEALESIYPDSFTVLSENPPSFTITVTSEAGENDETVQTTLKFTYSEKY 60
D G +QR E+EA+ +IY + + V+ + F I ++ + + T+ L+ +Y
Sbjct: 5 DAGSDQRQNEEIEAMAAIYGEEWCVIDDCAKIFCIRISDDIDDPKWTL--CLQVMLPNEY 62
Query: 61 PDEA-PLYEIFSQ--ENLEDNDVSDILKLLALQAEENLGMVMIFTLVTAVQEKLNEIVDQ 117
P A P+Y++ + + E D+S+ L+ + +Q N+G +++ V +++ L + Q
Sbjct: 63 PGTAPPIYQLNAPWLKGQERADLSNSLEEIYIQ---NIGESILYLWVEKIRDVLIQ-KSQ 118
Query: 118 IKTRREEEKKQKEKEAEEAEKQL 140
+ + KK+ E+E E E L
Sbjct: 119 MTEPGPDVKKKTEEEDVECEDDL 141
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 38.9 bits (89), Expect = 0.004
Identities = 39/162 (24%), Positives = 72/162 (44%), Gaps = 27/162 (16%)
Query: 90 QAEENLGMVMIFTLVTAVQEKLNEIVDQIKTRR----EEEKKQKEKEAEEAEKQLFHGTP 145
++ ENL VM++ + + E +++++++R E E+KQK +AE Q T
Sbjct: 581 KSRENLSAVMLYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQ 640
Query: 146 VTIENFLNWKAKFDAELLEIKKKRMKEEEQAGKNKLSGKQLFETDHNLDTSDI------- 198
+ + + E L K+R E K+ L+ K+ FE + + +I
Sbjct: 641 RKETEIVQLQIRKQEESL---KRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQ 697
Query: 199 ------------QFLEDAGNNVEVDE-SLFQEMDDLELEDDE 227
Q L++ NN + ++ +FQE+D L+ E DE
Sbjct: 698 EEETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDE 739
Score = 28.1 bits (61), Expect = 7.2
Identities = 50/210 (23%), Positives = 94/210 (44%), Gaps = 41/210 (19%)
Query: 58 EKYPDEAPLYEIFSQENLEDNDVSDILKLLALQAEENLGMVMIFTLVTAVQEKLNEIVDQ 117
EK + E QE ++I++L + EE+L ++ KL +++ +
Sbjct: 621 EKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFH-----IENKLKDLLAE 675
Query: 118 IKTRREEEKKQKEKEAEEAEKQLFHGTPVTIENFL--------NWKA-KFDA--EL---- 162
K + EEE+ ++++E E +K+ T + ++ L N KA KF EL
Sbjct: 676 -KEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQ 734
Query: 163 ---------LEIKKKRMKEEEQAG-------KNKLSGKQLFETDHNLDTSDIQFLEDAGN 206
LE++KKR++E+E+ + +L KQ E L ++Q++E+
Sbjct: 735 KEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQ--EMIQLLRRGEVQWVEEEKR 792
Query: 207 NVE-VDESLFQEMDDLELEDDEDDPDYNPA 235
++E + ESL + + + DED + A
Sbjct: 793 DLEGIRESLLR-VKEARAGGDEDGEELEKA 821
>gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo
sapiens]
Length = 1150
Score = 38.5 bits (88), Expect = 0.005
Identities = 32/121 (26%), Positives = 52/121 (42%), Gaps = 18/121 (14%)
Query: 123 EEEKKQKEKEAEEAEKQLFHGTPVTIENFLNWKAKFDAELLEIKKKRMKEEEQAGKNKLS 182
+E+KK+K+K++++ E++ + K + D E E K KR K + K +
Sbjct: 796 KEDKKEKDKKSKKDERK-------------DKKEERDDETDEPKPKRRKSGDDKDKKEDR 842
Query: 183 GKQLFETDHNLDTSDIQFLEDAGNNVEVDESLFQEMDDLELEDDEDDPDYNPADPESDSA 242
++ E D+ D E+ N E D M+ E ED+EDD D D
Sbjct: 843 DERKKEDKRKDDSKDDDETEEDNNQDEYDP-----MEAEEAEDEEDDRDEEEMTKRDDKR 897
Query: 243 D 243
D
Sbjct: 898 D 898
Score = 33.1 bits (74), Expect = 0.22
Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 14/110 (12%)
Query: 92 EENLGMVMIFTLVTAVQEKLNEIVDQIKTRREEEKKQK--EKEAEEAEKQLFHGTPVTIE 149
EEN+G+++ + V L ++ K R E E+K + E++ +E EK TI
Sbjct: 1019 EENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEK--------TIL 1070
Query: 150 NFLNWKAKFDAELLEIKKKRMKEEE----QAGKNKLSGKQLFETDHNLDT 195
N N EL E+KK + +E N Q+ +T NL T
Sbjct: 1071 NLENSNKSLSGELREVKKDLSQLQENLKISENMNLQFENQMNKTIRNLST 1120
Score = 30.4 bits (67), Expect = 1.5
Identities = 30/124 (24%), Positives = 54/124 (43%), Gaps = 15/124 (12%)
Query: 117 QIKTRREEEKKQKEKEAEEAEKQLFHGTPVTIENFLNWKAKFDAELLEIKKKRMKEEEQA 176
Q+ + + E+K+ + E +E EK G I +W +K D + +++ R + E +A
Sbjct: 596 QLVEKLQGERKEADGEQDEEEKD--DGEAKEISTPTHW-SKLDPKTMKVNDLRKELESRA 652
Query: 177 GKNKLSGKQLFETDHNLDTSDIQFLEDAGNNVEVDESLFQEMDDLELEDDEDDPDYNPAD 236
+K QL T ++ E E+++S E E+DEDD + D
Sbjct: 653 LSSKGLKSQLIARL----TKQLKVEEQKEEQKELEKS--------EKEEDEDDDRKSEDD 700
Query: 237 PESD 240
E +
Sbjct: 701 KEEE 704
>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform
b [Homo sapiens]
Length = 1524
Score = 38.5 bits (88), Expect = 0.005
Identities = 30/121 (24%), Positives = 60/121 (49%), Gaps = 21/121 (17%)
Query: 114 IVDQIKTRREEEKKQKEKEAEEAEKQLFHGTPVTIENFLNWKAKFDAELLEIKKKRMKEE 173
I D + R+ +++ +E +AE+ K+ + + A + + K++++KE+
Sbjct: 602 IEDYVDILRQAKQEFRELKAEQHRKE---------------REEAAARIRKRKEEKLKEQ 646
Query: 174 EQAGKNKLSGKQLFETDHNLDTSDIQF----LEDAGNNVEVDESLFQEMDDLELEDDEDD 229
EQ K K ++L E + T+DI ED ++E ++ +E+D + +DEDD
Sbjct: 647 EQKMKEKQ--EKLKEDEQRNSTADISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDD 704
Query: 230 P 230
P
Sbjct: 705 P 705
Score = 29.6 bits (65), Expect = 2.5
Identities = 16/61 (26%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
Query: 108 QEKLNEIVDQIKTRREEEKKQKEKEAEEAEKQLFHGTPVTIENFLNW-KAKFDAELLEIK 166
+E+L +IV++ + +++EEK++ + E E+ ++L +E W K + D E ++K
Sbjct: 349 REELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDMECDDLK 408
Query: 167 K 167
+
Sbjct: 409 E 409
>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform
a [Homo sapiens]
Length = 1556
Score = 38.5 bits (88), Expect = 0.005
Identities = 30/121 (24%), Positives = 60/121 (49%), Gaps = 21/121 (17%)
Query: 114 IVDQIKTRREEEKKQKEKEAEEAEKQLFHGTPVTIENFLNWKAKFDAELLEIKKKRMKEE 173
I D + R+ +++ +E +AE+ K+ + + A + + K++++KE+
Sbjct: 634 IEDYVDILRQAKQEFRELKAEQHRKE---------------REEAAARIRKRKEEKLKEQ 678
Query: 174 EQAGKNKLSGKQLFETDHNLDTSDIQF----LEDAGNNVEVDESLFQEMDDLELEDDEDD 229
EQ K K ++L E + T+DI ED ++E ++ +E+D + +DEDD
Sbjct: 679 EQKMKEKQ--EKLKEDEQRNSTADISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDD 736
Query: 230 P 230
P
Sbjct: 737 P 737
Score = 29.6 bits (65), Expect = 2.5
Identities = 16/61 (26%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
Query: 108 QEKLNEIVDQIKTRREEEKKQKEKEAEEAEKQLFHGTPVTIENFLNW-KAKFDAELLEIK 166
+E+L +IV++ + +++EEK++ + E E+ ++L +E W K + D E ++K
Sbjct: 349 REELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDMECDDLK 408
Query: 167 K 167
+
Sbjct: 409 E 409
>gi|169161522 PREDICTED: similar to cell division cycle 2-like 1
(PITSLRE proteins) [Homo sapiens]
Length = 155
Score = 37.7 bits (86), Expect = 0.009
Identities = 23/77 (29%), Positives = 40/77 (51%), Gaps = 2/77 (2%)
Query: 153 NWKAKFDAELLEIKKKRMKEEEQAGKNKLSGKQLFETDHNLDTSDIQFLEDAGNNVEVDE 212
+WK K E+L+ KK+R ++EE+A +L K + D D+ + L D + +
Sbjct: 7 SWKVKTLDEILQEKKRRKEQEEKAEIKRL--KNSDDRDSKRDSLEEGELRDHRMEITIRN 64
Query: 213 SLFQEMDDLELEDDEDD 229
S ++ D +E +EDD
Sbjct: 65 SPYRREDSMEDRGEEDD 81
>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
[Homo sapiens]
Length = 8749
Score = 37.7 bits (86), Expect = 0.009
Identities = 41/181 (22%), Positives = 80/181 (44%), Gaps = 18/181 (9%)
Query: 45 DETVQTTLKFTYSEK---YPDEAPLYEIFSQENLEDNDVSDILKLLALQAEENLGMVMIF 101
DE ++T + + E+ Y DE +QE L+++ V+ + A Q
Sbjct: 3618 DEWLKTAEEKKWHEEVTAYRDEVEEVGARAQEILDESHVNSRMGCQATQ----------- 3666
Query: 102 TLVTAVQEKLNEIVDQIKTRREEEKKQKEKEAEEAEKQLFHGTPVTIENFLNWKAKFDAE 161
L + Q L ++++QIK EE + +E E+ + ++G+ T +NF N K D
Sbjct: 3667 -LTSRYQALLLQVLEQIKFLEEEIQSLEESESSLSSYSDWYGS--THKNFKNVATKIDKV 3723
Query: 162 LLEIKKKRMKEEEQAGKNKLSGKQLFETDHNLDTSDIQFLEDAGNNVEVDESLFQEMDDL 221
+ K++K E K+ G L ++ +++LE+ G + + + M+ L
Sbjct: 3724 DTVMMGKKLKTLEVLLKDMEKGHSLLKSAREKGERAVKYLEE-GEAERLRKEIHDHMEQL 3782
Query: 222 E 222
+
Sbjct: 3783 K 3783
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 37.7 bits (86), Expect = 0.009
Identities = 36/133 (27%), Positives = 65/133 (48%), Gaps = 13/133 (9%)
Query: 118 IKTRREEEKKQKEKEAEEAEKQLFHGTPVTIENFLNWKAKFDAELLEIKKK---RMKEEE 174
+++ E +K A F G+ L+ K E++++ KK ++K +E
Sbjct: 494 LESEAVNENLRKNLTRATARAPYFSGSSTFSPTILS-SDKETIEIIDLAKKDLEKLKRKE 552
Query: 175 QAGKNKLSGKQLFETDHNLDTSDIQFLEDAGNN-VEVDESLFQEMDDLE-----LEDDED 228
+ K ++GK+ TD + + + + + + NN +EV+ES QE+ D E E++ED
Sbjct: 553 KRKKKSVAGKE-DNTDTDQEKKEEKGVSERENNELEVEES--QEVSDHEDEEEEEEEEED 609
Query: 229 DPDYNPADPESDS 241
D D + ESDS
Sbjct: 610 DIDGGESSDESDS 622
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 37.7 bits (86), Expect = 0.009
Identities = 23/77 (29%), Positives = 40/77 (51%), Gaps = 2/77 (2%)
Query: 153 NWKAKFDAELLEIKKKRMKEEEQAGKNKLSGKQLFETDHNLDTSDIQFLEDAGNNVEVDE 212
+WK K E+L+ KK+R ++EE+A +L K + D D+ + L D + +
Sbjct: 7 SWKVKTLDEILQEKKRRKEQEEKAEIKRL--KNSDDRDSKRDSLEEGELRDHRMEITIRN 64
Query: 213 SLFQEMDDLELEDDEDD 229
S ++ D +E +EDD
Sbjct: 65 SPYRREDSMEDRGEEDD 81
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 37.4 bits (85), Expect = 0.012
Identities = 23/77 (29%), Positives = 40/77 (51%), Gaps = 2/77 (2%)
Query: 153 NWKAKFDAELLEIKKKRMKEEEQAGKNKLSGKQLFETDHNLDTSDIQFLEDAGNNVEVDE 212
+WK K E+L+ KK+R ++EE+A +L K + D D+ + L D + +
Sbjct: 7 SWKVKTLDEILQEKKRRKEQEEKAEIKRL--KNSDDRDSKRDSLEEGELRDHCMEITIRN 64
Query: 213 SLFQEMDDLELEDDEDD 229
S ++ D +E +EDD
Sbjct: 65 SPYRREDSMEDRGEEDD 81
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 37.4 bits (85), Expect = 0.012
Identities = 23/77 (29%), Positives = 40/77 (51%), Gaps = 2/77 (2%)
Query: 153 NWKAKFDAELLEIKKKRMKEEEQAGKNKLSGKQLFETDHNLDTSDIQFLEDAGNNVEVDE 212
+WK K E+L+ KK+R ++EE+A +L K + D D+ + L D + +
Sbjct: 7 SWKVKTLDEILQEKKRRKEQEEKAEIKRL--KNSDDRDSKRDSLEEGELRDHCMEITIRN 64
Query: 213 SLFQEMDDLELEDDEDD 229
S ++ D +E +EDD
Sbjct: 65 SPYRREDSMEDRGEEDD 81
>gi|239747195 PREDICTED: similar to PITSLRE protein kinase beta SV2
[Homo sapiens]
Length = 153
Score = 37.4 bits (85), Expect = 0.012
Identities = 23/77 (29%), Positives = 40/77 (51%), Gaps = 2/77 (2%)
Query: 153 NWKAKFDAELLEIKKKRMKEEEQAGKNKLSGKQLFETDHNLDTSDIQFLEDAGNNVEVDE 212
+WK K E+L+ KK+R ++EE+A +L K + D D+ + L D + +
Sbjct: 7 SWKVKTLDEILQEKKRRKEQEEKAEIKRL--KNSDDRDSKRDSLEEGELRDHCMEITIRN 64
Query: 213 SLFQEMDDLELEDDEDD 229
S ++ D +E +EDD
Sbjct: 65 SPYRREDSMEDRGEEDD 81
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 37.4 bits (85), Expect = 0.012
Identities = 23/77 (29%), Positives = 40/77 (51%), Gaps = 2/77 (2%)
Query: 153 NWKAKFDAELLEIKKKRMKEEEQAGKNKLSGKQLFETDHNLDTSDIQFLEDAGNNVEVDE 212
+WK K E+L+ KK+R ++EE+A +L K + D D+ + L D + +
Sbjct: 7 SWKVKTLDEILQEKKRRKEQEEKAEIKRL--KNSDDRDSKRDSLEEGELRDHCMEITIRN 64
Query: 213 SLFQEMDDLELEDDEDD 229
S ++ D +E +EDD
Sbjct: 65 SPYRREDSMEDRGEEDD 81
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 37.4 bits (85), Expect = 0.012
Identities = 23/77 (29%), Positives = 40/77 (51%), Gaps = 2/77 (2%)
Query: 153 NWKAKFDAELLEIKKKRMKEEEQAGKNKLSGKQLFETDHNLDTSDIQFLEDAGNNVEVDE 212
+WK K E+L+ KK+R ++EE+A +L K + D D+ + L D + +
Sbjct: 7 SWKVKTLDEILQEKKRRKEQEEKAEIKRL--KNSDDRDSKRDSLEEGELRDHCMEITIRN 64
Query: 213 SLFQEMDDLELEDDEDD 229
S ++ D +E +EDD
Sbjct: 65 SPYRREDSMEDRGEEDD 81
>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
Length = 569
Score = 37.4 bits (85), Expect = 0.012
Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 26/121 (21%)
Query: 116 DQIKTRREEEKKQKEKEAEEAEKQLFHGTPVTIENFLNWKAKFDAELLEIKKKRMKEEEQ 175
DQ K R +++ KEKE EE +K E + K + + E E K++ +EEE
Sbjct: 361 DQRKRMRAFQQEMKEKEEEEMKK----------EEEMKKKEEKEEEEEEEMKQKEEEEEI 410
Query: 176 AGKNKLSGKQLFETDHNLDTSDIQFLEDAGNNVEVD-------ESLFQEMDDLELEDDED 228
KN+ G+ E D + ED G E + E + E+++ L++ +D
Sbjct: 411 RNKNEEEGESKDEEDED---------EDGGQKPEGEPQQDPGTEETYGEVEEEPLDEAQD 461
Query: 229 D 229
D
Sbjct: 462 D 462
>gi|8922712 septin 11 [Homo sapiens]
Length = 429
Score = 37.0 bits (84), Expect = 0.016
Identities = 27/96 (28%), Positives = 46/96 (47%), Gaps = 12/96 (12%)
Query: 101 FTLVTAVQEKLNEIVDQIKTRREEEK-------KQKEKEAEEAEKQLFHGTPVTIENFLN 153
F+L + K NE + +++ + EE + K+KE E +EAEK+L +
Sbjct: 317 FSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVKEKEAELKEAEKELHEKFDLLKRTHQE 376
Query: 154 WKAKFDAELLEIKKKRMKEEEQAGKNKLSGKQLFET 189
K K +E KKK ++EE + K + QL ++
Sbjct: 377 EKKK-----VEDKKKELEEEVNNFQKKKAAAQLLQS 407
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 36.6 bits (83), Expect = 0.020
Identities = 25/122 (20%), Positives = 62/122 (50%), Gaps = 12/122 (9%)
Query: 107 VQEKLNEIVDQIKTRREEEKKQKEKEAEEAEKQLFHGTPVTIENFLNWKAKFDAELLEIK 166
++EK + +Q K ++EEK ++EK+ +E EK+ + E E + +
Sbjct: 516 LREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREE----------ERMRER 565
Query: 167 KKRMKEEEQAGKNKLSGKQLFETDHNLDTSDIQFLEDAGNNVEVDESLFQEMDDLELEDD 226
+K+M+EEE+ + + +++ E + + + + E E +E ++++ + + +++
Sbjct: 566 EKKMREEEEMMREQ--EEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 623
Query: 227 ED 228
ED
Sbjct: 624 ED 625
Score = 30.4 bits (67), Expect = 1.5
Identities = 24/86 (27%), Positives = 45/86 (52%), Gaps = 19/86 (22%)
Query: 108 QEKLNEIVDQIKTRREEEKKQKEKEAEEAEKQLFHGTPVTIENFLNWKAKFDAELLEIKK 167
Q+KL E +Q++ + E+ +Q+EK E+ EK W+ + E L ++
Sbjct: 302 QKKLREQEEQMQEQEEKMWEQEEKMREQEEKM--------------WRQE---ERLWEQE 344
Query: 168 KRMKEEEQAGKNKLSGKQLFETDHNL 193
K+M+E+EQ K + ++++E D L
Sbjct: 345 KQMREQEQ--KMRDQEERMWEQDERL 368
Score = 29.6 bits (65), Expect = 2.5
Identities = 22/105 (20%), Positives = 51/105 (48%), Gaps = 6/105 (5%)
Query: 121 RREEEKKQKEKEAEEAEKQLFHGTPVTIENFLNWKAKFDAELLEIKKKRMKEEE----QA 176
R+EEE +++EK+ + E++++ E K + E + ++KR++E+E +
Sbjct: 238 RQEEELREQEKKIRKQEEKMWRQEERLREQ--EGKMREQEEKMRRQEKRLREQEKELREQ 295
Query: 177 GKNKLSGKQLFETDHNLDTSDIQFLEDAGNNVEVDESLFQEMDDL 221
K K+L E + + + + E E +E ++++ + L
Sbjct: 296 EKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL 340
Score = 28.1 bits (61), Expect = 7.2
Identities = 23/121 (19%), Positives = 56/121 (46%), Gaps = 11/121 (9%)
Query: 108 QEKLNEIVDQIKTRREEEKKQKEKEAEEAEKQLFHGTPVTIENFLNWKAKFDAELLEIKK 167
QEK+ E DQ+ + E+ + Q++K ++ E+ + + + E + +K
Sbjct: 478 QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQ----------DERLREKEERMREQK 527
Query: 168 KRMKEEEQAGKNKLSGKQLFET-DHNLDTSDIQFLEDAGNNVEVDESLFQEMDDLELEDD 226
K ++EE+ + K + +Q +T D + + + + + +E + +E ++ E +
Sbjct: 528 KMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQE 587
Query: 227 E 227
E
Sbjct: 588 E 588
>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
[Homo sapiens]
Length = 8797
Score = 36.6 bits (83), Expect = 0.020
Identities = 37/163 (22%), Positives = 71/163 (43%), Gaps = 15/163 (9%)
Query: 60 YPDEAPLYEIFSQENLEDNDVSDILKLLALQAEENLGMVMIFTLVTAVQEKLNEIVDQIK 119
Y DE +QE L+++ V+ + A Q L + Q L ++++QIK
Sbjct: 3651 YRDEVEEVGARAQEILDESHVNSRMGCQATQ------------LTSRYQALLLQVLEQIK 3698
Query: 120 TRREEEKKQKEKEAEEAEKQLFHGTPVTIENFLNWKAKFDAELLEIKKKRMKEEEQAGKN 179
EE + +E E+ + ++G+ T +NF N K D + K++K E K+
Sbjct: 3699 FLEEEIQSLEESESSLSSYSDWYGS--THKNFKNVATKIDKVDTVMMGKKLKTLEVLLKD 3756
Query: 180 KLSGKQLFETDHNLDTSDIQFLEDAGNNVEVDESLFQEMDDLE 222
G L ++ +++LE+ G + + + M+ L+
Sbjct: 3757 MEKGHSLLKSAREKGERAVKYLEE-GEAERLRKEIHDHMEQLK 3798
>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
Length = 556
Score = 36.6 bits (83), Expect = 0.020
Identities = 40/180 (22%), Positives = 79/180 (43%), Gaps = 22/180 (12%)
Query: 7 EQRNELEALESIYPDSFTVLSENPPSFTITVTSEAGENDETVQTTLKFTYSEKYPDEAPL 66
++ N A +++ S + P+ +SE E +T K ++ P +A +
Sbjct: 128 KEENPRRASKAVEESSDEERQRDLPAQRGEESSEEEEKGYKGKTRKKPVVKKQAPGKASV 187
Query: 67 YEIFSQENLEDNDVSDILKLLALQAEENLGMVMIFTLVTAVQEKLNEIVDQIKTRREEEK 126
++E E+++ + + A + E N G +L + QE EI+ Q K +REEE
Sbjct: 188 SRKQAREESEESEAEPVQRT-AKKVEGNKGTK---SLKESEQESEEEILAQKKEQREEEV 243
Query: 127 KQKEKEAEEAEKQLFHGTPVTIENFLNWKAKFDAELLEIKKKRMKEEEQAGKNKLSGKQL 186
+++EKE +E + +WK + + +++ EE++ K K K+L
Sbjct: 244 EEEEKEEDEEKG--------------DWKPRTRSN----GRRKSAREERSCKQKSQAKRL 285
>gi|195976782 Paf1/RNA polymerase II complex component [Homo
sapiens]
Length = 710
Score = 36.6 bits (83), Expect = 0.020
Identities = 39/133 (29%), Positives = 67/133 (50%), Gaps = 14/133 (10%)
Query: 113 EIVDQIKTRREEEKKQKEKEAEEAEKQ----LFHGTPVTIENFLNWKAKFDAELLEIKKK 168
EI ++KT +++EKK+K+K+ EE +++ + VT N ++K D E L+ K +
Sbjct: 223 EIKKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHN-KERRSKRD-EKLDKKSQ 280
Query: 169 RMKE---EEQAGKNK----LSGKQLFETDHNLDTSDIQFLEDAGNNVEVDESLFQEMDDL 221
M+E E + KN+ L+ KQ +T + + D + ED ++ + D S D
Sbjct: 281 AMEELKAEREKRKNRTAELLAKKQPLKTS-EVYSDDEEEEEDDKSSEKSDRSSRTSSSDE 339
Query: 222 ELEDDEDDPDYNP 234
E E +E P P
Sbjct: 340 EEEKEEIPPKSQP 352
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.127 0.340
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,164,553
Number of Sequences: 37866
Number of extensions: 419034
Number of successful extensions: 4769
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 89
Number of HSP's successfully gapped in prelim test: 342
Number of HSP's that attempted gapping in prelim test: 3498
Number of HSP's gapped (non-prelim): 1278
length of query: 243
length of database: 18,247,518
effective HSP length: 99
effective length of query: 144
effective length of database: 14,498,784
effective search space: 2087824896
effective search space used: 2087824896
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.