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Search of human proteins with 55770898
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55770898 Rho GTPase activating protein 25 isoform a [Homo
sapiens]
(645 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55770898 Rho GTPase activating protein 25 isoform a [Homo sap... 1295 0.0
gi|7661882 Rho GTPase activating protein 25 isoform b [Homo sapi... 1256 0.0
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens] 466 e-131
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa... 425 e-119
gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa... 342 6e-94
gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sa... 315 8e-86
gi|54860079 nadrin isoform 1 [Homo sapiens] 99 2e-20
gi|54860105 nadrin isoform 2 [Homo sapiens] 99 2e-20
gi|56119110 family with sequence similarity 13, member A1 isofor... 97 6e-20
gi|4757766 Rho GTPase activating protein 1 [Homo sapiens] 95 2e-19
gi|112363100 SLIT-ROBO Rho GTPase activating protein 2 isoform a... 92 1e-18
gi|112363096 SLIT-ROBO Rho GTPase activating protein 2 isoform b... 92 1e-18
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] 92 2e-18
gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo sapi... 90 7e-18
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] 90 7e-18
gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b ... 89 1e-17
gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a ... 89 1e-17
gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens] 89 1e-17
gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens] 89 1e-17
gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 89 2e-17
gi|156142190 hypothetical protein LOC51306 isoform 2 [Homo sapiens] 88 2e-17
gi|156142188 hypothetical protein LOC51306 isoform 1 [Homo sapiens] 88 2e-17
gi|224458284 Rho GTPase activating protein 23 [Homo sapiens] 87 6e-17
gi|4757980 beta chimerin isoform 2 [Homo sapiens] 87 6e-17
gi|91106928 beta chimerin isoform 1 [Homo sapiens] 87 6e-17
gi|229094128 active breakpoint cluster region-related protein i... 86 1e-16
gi|38679957 active breakpoint cluster region-related protein is... 86 1e-16
gi|38679954 active breakpoint cluster region-related protein is... 86 1e-16
gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens] 86 1e-16
gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens] 85 2e-16
>gi|55770898 Rho GTPase activating protein 25 isoform a [Homo
sapiens]
Length = 645
Score = 1295 bits (3351), Expect = 0.0
Identities = 645/645 (100%), Positives = 645/645 (100%)
Query: 1 MSLKLPRNWDFNLKVEAAKIARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIV 60
MSLKLPRNWDFNLKVEAAKIARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIV
Sbjct: 1 MSLKLPRNWDFNLKVEAAKIARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIV 60
Query: 61 KNWQQRYFVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWD 120
KNWQQRYFVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWD
Sbjct: 61 KNWQQRYFVLRAQQLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWD 120
Query: 121 QNRMGQDSYVLMASSQAEMEEWVKFLRRVAGTPCGVFGQRLDETVAYEQKFGPHLVPILV 180
QNRMGQDSYVLMASSQAEMEEWVKFLRRVAGTPCGVFGQRLDETVAYEQKFGPHLVPILV
Sbjct: 121 QNRMGQDSYVLMASSQAEMEEWVKFLRRVAGTPCGVFGQRLDETVAYEQKFGPHLVPILV 180
Query: 181 EKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLR 240
EKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLR
Sbjct: 181 EKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLR 240
Query: 241 DLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQL 300
DLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQL
Sbjct: 241 DLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQL 300
Query: 301 NCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIP 360
NCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIP
Sbjct: 301 NCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIP 360
Query: 361 LSPPAQKNDPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPED 420
LSPPAQKNDPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPED
Sbjct: 361 LSPPAQKNDPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPED 420
Query: 421 SSKVPREKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEAKAGE 480
SSKVPREKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEAKAGE
Sbjct: 421 SSKVPREKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEAKAGE 480
Query: 481 GHRRTMSQDLRQLSDSQRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNSETGP 540
GHRRTMSQDLRQLSDSQRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNSETGP
Sbjct: 481 GHRRTMSQDLRQLSDSQRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNSETGP 540
Query: 541 GKKNSGEEEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEK 600
GKKNSGEEEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEK
Sbjct: 541 GKKNSGEEEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEK 600
Query: 601 KKSAALEISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTEA 645
KKSAALEISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTEA
Sbjct: 601 KKSAALEISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTEA 645
>gi|7661882 Rho GTPase activating protein 25 isoform b [Homo
sapiens]
Length = 638
Score = 1256 bits (3251), Expect = 0.0
Identities = 626/626 (100%), Positives = 626/626 (100%)
Query: 20 IARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIVKNWQQRYFVLRAQQLYYYK 79
IARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIVKNWQQRYFVLRAQQLYYYK
Sbjct: 13 IARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIVKNWQQRYFVLRAQQLYYYK 72
Query: 80 DEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWDQNRMGQDSYVLMASSQAEM 139
DEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWDQNRMGQDSYVLMASSQAEM
Sbjct: 73 DEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWDQNRMGQDSYVLMASSQAEM 132
Query: 140 EEWVKFLRRVAGTPCGVFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGRNEEGIFR 199
EEWVKFLRRVAGTPCGVFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGRNEEGIFR
Sbjct: 133 EEWVKFLRRVAGTPCGVFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGRNEEGIFR 192
Query: 200 LPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCG 259
LPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCG
Sbjct: 193 LPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCG 252
Query: 260 QLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMSVDNLATVIGVN 319
QLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMSVDNLATVIGVN
Sbjct: 253 QLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMSVDNLATVIGVN 312
Query: 320 LIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIPLSPPAQKNDPKKAPVARSS 379
LIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIPLSPPAQKNDPKKAPVARSS
Sbjct: 313 LIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIPLSPPAQKNDPKKAPVARSS 372
Query: 380 VGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPEDSSKVPREKPGDWKMQSRKR 439
VGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPEDSSKVPREKPGDWKMQSRKR
Sbjct: 373 VGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPEDSSKVPREKPGDWKMQSRKR 432
Query: 440 TQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEAKAGEGHRRTMSQDLRQLSDSQRT 499
TQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEAKAGEGHRRTMSQDLRQLSDSQRT
Sbjct: 433 TQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEAKAGEGHRRTMSQDLRQLSDSQRT 492
Query: 500 STYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNSETGPGKKNSGEEEIDSLQRMVQE 559
STYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNSETGPGKKNSGEEEIDSLQRMVQE
Sbjct: 493 STYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNSETGPGKKNSGEEEIDSLQRMVQE 552
Query: 560 LRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEKKKSAALEISLRNMERSRED 619
LRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEKKKSAALEISLRNMERSRED
Sbjct: 553 LRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEKKKSAALEISLRNMERSRED 612
Query: 620 VEKRNKALEEEVKEFVKSMKEPKTEA 645
VEKRNKALEEEVKEFVKSMKEPKTEA
Sbjct: 613 VEKRNKALEEEVKEFVKSMKEPKTEA 638
>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
Length = 698
Score = 466 bits (1199), Expect = e-131
Identities = 287/694 (41%), Positives = 389/694 (56%), Gaps = 83/694 (11%)
Query: 14 KVEAAKIARSRSVMTGEQMAAFHPSSTPNPLERPIKMGWLKKQRSIVKNWQQRYFVLRAQ 73
K+ A+ ARS+S++ GEQ + P+ L +K GWLKKQRSI+KNWQQR+FVLR
Sbjct: 5 KIRQARRARSKSLVMGEQSRSPGRMPCPHRLGPVLKAGWLKKQRSIMKNWQQRWFVLRGD 64
Query: 74 QLYYYKDEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWDQNRM---GQDSYV 130
QL+YYKD+++ KPQG + L G + E+ PE+ GK +FEI P + ++ +
Sbjct: 65 QLFYYKDKDEIKPQGFISLQGTQVTELPPGPEDPGKHLFEISPGGAGEREKVPANPEALL 124
Query: 131 LMASSQAEMEEWVKFLRRVAGTPCG--VFGQRLDETVAYEQKFGPHLVPILVEKCAEFIL 188
LMASSQ +ME+WV+ +RRV P G +FGQRL+ETV +E+K+GP L P+LVE+C +FI
Sbjct: 125 LMASSQRDMEDWVQAIRRVIWAPLGGGIFGQRLEETVHHERKYGPRLAPLLVEQCVDFIR 184
Query: 189 EHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVP 248
E G EEG+FR+PGQ NLV+ L+D+FD GE+P FD TDVHTVASLLKLYLR+LPEPVVP
Sbjct: 185 ERGLTEEGLFRMPGQANLVRDLQDSFDCGEKPLFDSTTDVHTVASLLKLYLRELPEPVVP 244
Query: 249 WSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMS 308
+++YE FL C QL DE + EL KQ+S LP+ NY+LL YIC+FL E+Q VNKMS
Sbjct: 245 FARYEDFLSCAQLLTKDEGEGTLELAKQVSNLPQANYNLLRYICKFLDEVQAYSNVNKMS 304
Query: 309 VDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIPLSPPAQKN 368
V NLATV G N++R +VEDP IM GT +Q +MT++IR H LF + +P P + +
Sbjct: 305 VQNLATVFGPNILRPQVEDPVTIMEGTSLVQHLMTVLIRKHSQLF--TAPVPEGPTSPRG 362
Query: 369 DPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPEDSSKVPREK 428
+ +VGW + E R S+ + T+S G A S+
Sbjct: 363 G------LQCAVGWGSEEVTRDSQGEPGGPGLPAHRTSSLDG-----AAVAVLSRTAPTG 411
Query: 429 PGDWKMQSRKRTQTLPNRKCFLT-------SAFQGANSSKMEIFKNEFWSPSSEAKAGEG 481
PG + K+ QTLP+ K S G +S ++ I + + + G
Sbjct: 412 PGS-RCSPGKKVQTLPSWKSSFRQPRSLSGSPKGGGSSLEVPIISSGGNWLMNGLSSLRG 470
Query: 482 HRRTMSQD-LRQLSDSQRTSTYDNVPS---LPGSPGE----------------------- 514
HRR S D L+ QR STYDNVP+ +PG P
Sbjct: 471 HRRASSGDRLKDSGSVQRLSTYDNVPAPGLVPGIPSVASMAWSGASSSESSVGGSLSSCT 530
Query: 515 -------------------EASALSSQACDSKGDTLASPNSETGPGKKNSGEEEIDS--- 552
E S L S + D K L E G G NS E DS
Sbjct: 531 ACRASDSSARSSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSEPSEPDSPTR 590
Query: 553 --------LQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEKKKSA 604
LQ +V ELR E+ Q+ YE +K +E+ + D+ ++ RL EEL++EKKK
Sbjct: 591 EHARRSEALQGLVTELRAELCRQRTEYERSVKRIEEGSADLRKRMSRLEEELDQEKKKYI 650
Query: 605 ALEISLRNMERSREDVEKRNKALEEEVKEFVKSM 638
LEI LRN ER+RED E+RN+ L+ E++EF ++
Sbjct: 651 MLEIKLRNSERAREDAERRNQLLQREMEEFFSTL 684
>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
sapiens]
Length = 748
Score = 425 bits (1092), Expect = e-119
Identities = 264/741 (35%), Positives = 386/741 (52%), Gaps = 147/741 (19%)
Query: 39 STPNPLE-----RPIKMGWLKKQRSIVKNWQQRYFVLRAQQLYYYKDEEDTKPQGCMYLP 93
ST NP + IK GWL+KQ VK W R+FVL+ QLYY+KDE++TKP G ++LP
Sbjct: 7 STENPQQGQGRQNAIKCGWLRKQGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLGTIFLP 66
Query: 94 GCTIKEIATNPEEAGKFVFEIIPASWDQNRM--GQDSYVLMASSQAEMEEWVKFLRRVAG 151
G + E N E GKF+FE++P D++RM +SY+LMAS+Q +ME+WVK +RRV
Sbjct: 67 GNKVSEHPCNEENPGKFLFEVVPGG-DRDRMTANHESYLLMASTQNDMEDWVKSIRRVIW 125
Query: 152 TPCG--VFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQ 209
P G +FGQ+L++TV YE+++G L P+LVE+C +FI + G EEG+FRLPGQ NLVK+
Sbjct: 126 GPFGGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKE 185
Query: 210 LRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKA 269
L+DAFD GE+PSFD +TDVHTVASLLKLYLR+LPEPV+P+++YE FL C +L + +E
Sbjct: 186 LQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAG 245
Query: 270 QQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMSVDNLATVIGVNLIRSKVEDPA 329
+EL KQ+ LP NY+LL YICRFL E+Q VNKMSV NLATV G N++R KVEDP
Sbjct: 246 VKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPL 305
Query: 330 VIMRGTPQIQRVMTMMIRDHEVLFPKSKDIPLSPP--------------------AQKND 369
IM GT +Q++M++MI H+ LFPK ++ P + N+
Sbjct: 306 TIMEGTVVVQQLMSVMISKHDCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQNKENNN 365
Query: 370 PKKAPVARSSVGWDATED-LRISRTDSFSSMTSDSDTTSPTGQ--------------QPS 414
K +P + S WD +E R S + + S S T SP + +
Sbjct: 366 TKDSPSRQCS--WDKSESPQRSSMNNGSPTALSGSKTNSPKNSVHKLDVSRSPPLMVKKN 423
Query: 415 DAFPEDSSKVPREKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEI---------- 464
AF + S V + ++TQT PN + Q SS +++
Sbjct: 424 PAFNKGSGIVTNGSFSSSNAEGLEKTQTTPN------GSLQARRSSSLKVSGTKMGTHSV 477
Query: 465 --------------------FKNEFWSPSSEAKAGEGHRRTMSQDLRQLSDSQRTSTYDN 504
+N W P+ + ++ + +L Q R STYDN
Sbjct: 478 QNGTVRMGILNSDTLGNPTNVRNMSWLPNGYVTLRDNKQKEQAGELGQ---HNRLSTYDN 534
Query: 505 V------PSLPGSPGEEASALSSQAC---------------------------------- 524
V +L +++ S+ +C
Sbjct: 535 VHQQFSMMNLDDKQSIDSATWSTSSCEISLPENSNSCRSSTTTCPEQDFFGGNFEDPVLD 594
Query: 525 -------------DSKGD--------TLASPNSETGPGKKNSGEEEIDSLQRMVQELRKE 563
+SK D + A+ +S+ + +L +V L++E
Sbjct: 595 GPPQDDLSHPRDYESKSDHRSVGGRSSRATSSSDNSETFVGNSSSNHSALHSLVSSLKQE 654
Query: 564 IETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEKEKKKSAALEISLRNMERSREDVEKR 623
+ QK YE +IK+LE+ N + +++ L++EL++E+KK +EI +RN ER++ED EKR
Sbjct: 655 MTKQKIEYESRIKSLEQRNLTLETEMMSLHDELDQERKKFTMIEIKMRNAERAKEDAEKR 714
Query: 624 NKALEEEVKEFVKSMKEPKTE 644
N L++E+++F + E E
Sbjct: 715 NDMLQKEMEQFFSTFGELTVE 735
>gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo
sapiens]
Length = 653
Score = 342 bits (877), Expect = 6e-94
Identities = 220/646 (34%), Positives = 327/646 (50%), Gaps = 139/646 (21%)
Query: 127 DSYVLMASSQAEMEEWVKFLRRVAGTPCG--VFGQRLDETVAYEQKFGPHLVPILVEKCA 184
+SY+LMAS+Q +ME+WVK +RRV P G +FGQ+L++TV YE+++G L P+LVE+C
Sbjct: 6 ESYLLMASTQNDMEDWVKSIRRVIWGPFGGGIFGQKLEDTVRYEKRYGNRLAPMLVEQCV 65
Query: 185 EFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPE 244
+FI + G EEG+FRLPGQ NLVK+L+DAFD GE+PSFD +TDVHTVASLLKLYLR+LPE
Sbjct: 66 DFIRQRGLKEEGLFRLPGQANLVKELQDAFDCGEKPSFDSNTDVHTVASLLKLYLRELPE 125
Query: 245 PVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAV 304
PV+P+++YE FL C +L + +E +EL KQ+ LP NY+LL YICRFL E+Q V
Sbjct: 126 PVIPYAKYEDFLSCAKLLSKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGV 185
Query: 305 NKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIPLSPP 364
NKMSV NLATV G N++R KVEDP IM GT +Q++M++MI H+ LFPK ++ P
Sbjct: 186 NKMSVQNLATVFGPNILRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAELQSKPQ 245
Query: 365 --------------------AQKNDPKKAPVARSSVGWDATED-LRISRTDSFSSMTSDS 403
+ N+ K +P + S WD +E R S + + S S
Sbjct: 246 DGVSNNNEIQKKATMGQLQNKENNNTKDSPSRQCS--WDKSESPQRSSMNNGSPTALSGS 303
Query: 404 DTTSPTGQ--------------QPSDAFPEDSSKVPREKPGDWKMQSRKRTQTLPNRKCF 449
T SP + + AF + S V + ++TQT PN
Sbjct: 304 KTNSPKNSVHKLDVSRSPPLMVKKNPAFNKGSGIVTNGSFSSSNAEGLEKTQTTPN---- 359
Query: 450 LTSAFQGANSSKMEI------------------------------FKNEFWSPSSEAKAG 479
+ Q SS +++ +N W P+
Sbjct: 360 --GSLQARRSSSLKVSGTKMGTHSVQNGTVRMGILNSDTLGNPTNVRNMSWLPNGYVTLR 417
Query: 480 EGHRRTMSQDLRQLSDSQRTSTYDNV------PSLPGSPGEEASALSSQAC--------- 524
+ ++ + +L Q R STYDNV +L +++ S+ +C
Sbjct: 418 DNKQKEQAGELGQ---HNRLSTYDNVHQQFSMMNLDDKQSIDSATWSTSSCEISLPENSN 474
Query: 525 --------------------------------------DSKGD--------TLASPNSET 538
+SK D + A+ +S+
Sbjct: 475 SCRSSTTTCPEQDFFGGNFEDPVLDGPPQDDLSHPRDYESKSDHRSVGGRSSRATSSSDN 534
Query: 539 GPGKKNSGEEEIDSLQRMVQELRKEIETQKQMYEEQIKNLEKENYDVWAKVVRLNEELEK 598
+ +L +V L++E+ QK YE +IK+LE+ N + +++ L++EL++
Sbjct: 535 SETFVGNSSSNHSALHSLVSSLKQEMTKQKIEYESRIKSLEQRNLTLETEMMSLHDELDQ 594
Query: 599 EKKKSAALEISLRNMERSREDVEKRNKALEEEVKEFVKSMKEPKTE 644
E+KK +EI +RN ER++ED EKRN L++E+++F + E E
Sbjct: 595 ERKKFTMIEIKMRNAERAKEDAEKRNDMLQKEMEQFFSTFGELTVE 640
>gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo
sapiens]
Length = 655
Score = 315 bits (807), Expect = 8e-86
Identities = 204/616 (33%), Positives = 305/616 (49%), Gaps = 137/616 (22%)
Query: 155 GVFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAF 214
G+FGQ+L++TV YE+++G L P+LVE+C +FI + G EEG+FRLPGQ NLVK+L+DAF
Sbjct: 38 GIFGQKLEDTVRYEKRYGNRLAPMLVEQCVDFIRQRGLKEEGLFRLPGQANLVKELQDAF 97
Query: 215 DAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELM 274
D GE+PSFD +TDVHTVASLLKLYLR+LPEPV+P+++YE FL C +L + +E +EL
Sbjct: 98 DCGEKPSFDSNTDVHTVASLLKLYLRELPEPVIPYAKYEDFLSCAKLLSKEEEAGVKELA 157
Query: 275 KQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRG 334
KQ+ LP NY+LL YICRFL E+Q VNKMSV NLATV G N++R KVEDP IM G
Sbjct: 158 KQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNILRPKVEDPLTIMEG 217
Query: 335 TPQIQRVMTMMIRDHEVLFPKSKDIPLSPP--------------------AQKNDPKKAP 374
T +Q++M++MI H+ LFPK ++ P + N+ K +P
Sbjct: 218 TVVVQQLMSVMISKHDCLFPKDAELQSKPQDGVSNNNEIQKKATMGQLQNKENNNTKDSP 277
Query: 375 VARSSVGWDATED-LRISRTDSFSSMTSDSDTTSPTGQ--------------QPSDAFPE 419
+ S WD +E R S + + S S T SP + + AF +
Sbjct: 278 SRQCS--WDKSESPQRSSMNNGSPTALSGSKTNSPKNSVHKLDVSRSPPLMVKKNPAFNK 335
Query: 420 DSSKVPREKPGDWKMQSRKRTQTLPNRKCFLTSAFQGANSSKMEI--------------- 464
S V + ++TQT PN + Q SS +++
Sbjct: 336 GSGIVTNGSFSSSNAEGLEKTQTTPN------GSLQARRSSSLKVSGTKMGTHSVQNGTV 389
Query: 465 ---------------FKNEFWSPSSEAKAGEGHRRTMSQDLRQLSDSQRTSTYDNV---- 505
+N W P+ + ++ + +L Q R STYDNV
Sbjct: 390 RMGILNSDTLGNPTNVRNMSWLPNGYVTLRDNKQKEQAGELGQ---HNRLSTYDNVHQQF 446
Query: 506 --PSLPGSPGEEASALSSQAC--------------------------------------- 524
+L +++ S+ +C
Sbjct: 447 SMMNLDDKQSIDSATWSTSSCEISLPENSNSCRSSTTTCPEQDFFGGNFEDPVLDGPPQD 506
Query: 525 --------DSKGD--------TLASPNSETGPGKKNSGEEEIDSLQRMVQELRKEIETQK 568
+SK D + A+ +S+ + +L +V L++E+ QK
Sbjct: 507 DLSHPRDYESKSDHRSVGGRSSRATSSSDNSETFVGNSSSNHSALHSLVSSLKQEMTKQK 566
Query: 569 QMYEEQIKNLEKENYDVWAKVVRLNEELEKEKKKSAALEISLRNMERSREDVEKRNKALE 628
YE +IK+LE+ N + +++ L++EL++E+KK +EI +RN ER++ED EKRN L+
Sbjct: 567 IEYESRIKSLEQRNLTLETEMMSLHDELDQERKKFTMIEIKMRNAERAKEDAEKRNDMLQ 626
Query: 629 EEVKEFVKSMKEPKTE 644
+E+++F + E E
Sbjct: 627 KEMEQFFSTFGELTVE 642
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 98.6 bits (244), Expect = 2e-20
Identities = 96/397 (24%), Positives = 160/397 (40%), Gaps = 48/397 (12%)
Query: 80 DEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWDQNRMGQDSYV-LMASSQAE 138
DE K + C + E GKF ++ A D +R + +A
Sbjct: 181 DEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRKALAVLEKTLPEMRAH 240
Query: 139 MEEWVKFLRRVAGTPCGVFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGRNEEGIF 198
++W + + GTP +R +A + +E C +LE G EEG+F
Sbjct: 241 QDKWAE--KPAFGTPLEEHLKRSGREIA-----------LPIEACVMLLLETGMKEEGLF 287
Query: 199 RLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLC 258
R+ + +K+L+ A D + +D H VA LK YLR+LPEP++ ++ YE +
Sbjct: 288 RIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQV 347
Query: 259 GQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMSVDNLATVIGV 318
+ D+ K Q+L + LP N+ Y+ +FL ++ VNKM+ N+A V+G
Sbjct: 348 ASV--QDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGP 405
Query: 319 NLIRSKVEDPAVIMRGTPQIQ--RVMTMMIRDHEVLFPKSKD-------IPLSPPAQK-- 367
NL+ ++ E M + V+ +I+ + FP+ + +PL+ P+
Sbjct: 406 NLLWARNEGTLAEMAAATSVHVVAVIEPIIQHADWFFPEEVEFNVSEAFVPLTTPSSNHS 465
Query: 368 ----NDPKKAPVARSSVGWDATEDLRISRTDSFSSMTSDSDT-----------TSPTGQQ 412
ND + R A + + + +SF D SP Q
Sbjct: 466 FHTGNDSDSGTLERKRPASMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHISPAFQP 525
Query: 413 PSDAFPEDSSKV----PREKPGDWKMQSRKRTQTLPN 445
P P D S V P P + +S T+P+
Sbjct: 526 PLP--PTDGSTVVPAGPEPPPQSSRAESSSGGGTVPS 560
>gi|54860105 nadrin isoform 2 [Homo sapiens]
Length = 803
Score = 98.6 bits (244), Expect = 2e-20
Identities = 107/459 (23%), Positives = 182/459 (39%), Gaps = 72/459 (15%)
Query: 80 DEEDTKPQGCMYLPGCTIKEIATNPEEAGKFVFEIIPASWDQNRMGQDSYV-LMASSQAE 138
DE K + C + E GKF ++ A D +R + +A
Sbjct: 181 DEAGNKVEQCKDQLAADMYNFMAKEGEYGKFFVTLLEAQADYHRKALAVLEKTLPEMRAH 240
Query: 139 MEEWVKFLRRVAGTPCGVFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGRNEEGIF 198
++W + + GTP +R +A + +E C +LE G EEG+F
Sbjct: 241 QDKWAE--KPAFGTPLEEHLKRSGREIA-----------LPIEACVMLLLETGMKEEGLF 287
Query: 199 RLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLC 258
R+ + +K+L+ A D + +D H VA LK YLR+LPEP++ ++ YE +
Sbjct: 288 RIGAGASKLKKLKAALDCSTSHLDEFYSDPHAVAGALKSYLRELPEPLMTFNLYEEWTQV 347
Query: 259 GQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMSVDNLATVIGV 318
+ D+ K Q+L + LP N+ Y+ +FL ++ VNKM+ N+A V+G
Sbjct: 348 ASV--QDQDKKLQDLWRTCQKLPPQNFVNFRYLIKFLAKLAQTSDVNKMTPSNIAIVLGP 405
Query: 319 NLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIPLSPPAQKNDPKKAPVARS 378
NL+ ++ E M + V + P Q D
Sbjct: 406 NLLWARNEGTLAEMAAATSVHVVAV-----------------IEPIIQHAD--------- 439
Query: 379 SVGWDATEDLRISRTDSFSSMTSDSDTTS-PTGQQPSDAFPEDSSKVPREKPGDWKMQS- 436
W E++ + +++F +T+ S S TG DS + R++P +
Sbjct: 440 ---WFFPEEVEFNVSEAFVPLTTPSSNHSFHTGND------SDSGTLERKRPASMAVMEG 490
Query: 437 ---RKRTQTLPNRKCFLTSAFQGANSSKMEIFKNEFWSPSSEAKAGEGHRRTMSQDLRQL 493
+K + P G N+S++ +N+ +A AG H+ +M Q
Sbjct: 491 DLVKKESPPKPKDPVSAAVPAPGRNNSQIASGQNQ-----PQAAAG-SHQLSMGQPHNAA 544
Query: 494 SDSQRT---STYDNVPS-------LPGSPGEEASALSSQ 522
S T + P+ PG PG ++S+ +SQ
Sbjct: 545 GPSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQ 583
>gi|56119110 family with sequence similarity 13, member A1 isoform a
[Homo sapiens]
Length = 1023
Score = 96.7 bits (239), Expect = 6e-20
Identities = 58/179 (32%), Positives = 100/179 (55%), Gaps = 6/179 (3%)
Query: 176 VPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLL 235
+P +V E++ +HG +EG+FR+ G +V+QLR F++G +D DV + ASLL
Sbjct: 58 IPAVVWNIVEYLTQHGLTQEGLFRVNGNVKVVEQLRLKFESGVPVELGKDGDVCSAASLL 117
Query: 236 KLYLRDLPEPVVPWSQYEGFLLCGQLTNAD-EAKAQQELMKQLSILPRDNYSLLSYICRF 294
KL+LR+LP+ ++ + F+ Q D + + ++L+K+ LP +Y LL Y+C+F
Sbjct: 118 KLFLRELPDSLITSALQPRFIQLFQDGRNDVQESSLRDLIKE---LPDTHYCLLKYLCQF 174
Query: 295 LHEIQLNCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLF 353
L ++ + N+M+V NLATV G N V M+ ++M ++ ++ LF
Sbjct: 175 LTKVAKHHVQNRMNVHNLATVFGPNCFH--VPPGLEGMKEQDLCNKIMAKILENYNTLF 231
Score = 31.2 bits (69), Expect = 3.1
Identities = 45/176 (25%), Positives = 77/176 (43%), Gaps = 28/176 (15%)
Query: 490 LRQLSDSQRTSTYDNVPSLPGSPGEEASALSSQACDSKGDTLASPNSETGPGKKNSG--- 546
+RQL D D+ P L SP A S Q D + PNS + +++S
Sbjct: 604 IRQLLDE------DSDPML--SPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLGS 655
Query: 547 --EEEID----SLQRMVQELRKEIETQKQMYEEQIK-----NLEKENYDV--WAK-VVRL 592
+E+ D L R +Q L+K+I + +EE+ K + + N +V W + +
Sbjct: 656 YDDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAKF 715
Query: 593 NEELEKEKKKSAALEISLRNMERSREDVEKRNKALE---EEVKEFVKSMKEPKTEA 645
+L++ K K + +++ R +RS + LE E+ +E V +P EA
Sbjct: 716 RRQLKESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQELVDKAIKPSVEA 771
>gi|4757766 Rho GTPase activating protein 1 [Homo sapiens]
Length = 439
Score = 94.7 bits (234), Expect = 2e-19
Identities = 58/183 (31%), Positives = 98/183 (53%), Gaps = 13/183 (7%)
Query: 176 VPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLL 235
+PI++ + ++ H EGIFR +V++++ ++ G FD+ ++H A +L
Sbjct: 259 IPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLPVDFDQYNELHLPAVIL 318
Query: 236 KLYLRDLPEPVVPWSQYE---GFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYIC 292
K +LR+LPEP++ + Y GFL N DE++ ++ L LP +NY +L ++
Sbjct: 319 KTFLRELPEPLLTFDLYPHVVGFL------NIDESQRVPATLQVLQTLPEENYQVLRFLT 372
Query: 293 RFLHEIQLNCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHE-V 351
FL +I + NKM+ NLA V G NL+ +K D A+ ++ I T + DH+
Sbjct: 373 AFLVQISAHSDQNKMTNTNLAVVFGPNLLWAK--DAAITLKAINPI-NTFTKFLLDHQGE 429
Query: 352 LFP 354
LFP
Sbjct: 430 LFP 432
>gi|112363100 SLIT-ROBO Rho GTPase activating protein 2 isoform a
[Homo sapiens]
Length = 1071
Score = 92.4 bits (228), Expect = 1e-18
Identities = 70/263 (26%), Positives = 116/263 (44%), Gaps = 13/263 (4%)
Query: 131 LMASSQAEMEEWVKFLRRVAGTPCGVFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEH 190
L+ QA+ + K L T C + R TV + +P++VE C FI H
Sbjct: 463 LITKLQAKHDLLQKTLGESQRTDCSL--ARRSSTVRKQDS--SQAIPLVVESCIRFISRH 518
Query: 191 GRNEEGIFRLPGQDNLVKQLRDAFDAGERP--SFDRDTDVHTVASLLKLYLRDLPEPVVP 248
G EGIFR+ G V +++AF+ GE P D D+ ++A +LKLY R L P+ P
Sbjct: 519 GLQHEGIFRVSGSQVEVNDIKNAFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFP 578
Query: 249 WSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMS 308
+ + C + N E + K L +LP+ ++ Y+ FL+ + N M
Sbjct: 579 KDIFHDLMACVTMDNLQERAL--HIRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMD 636
Query: 309 VDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIP---LSPPA 365
NLA G +L+ V + + ++ +I HE +FP +++ S
Sbjct: 637 PYNLAICFGPSLMSVPEGHDQVSCQA--HVNELIKTIIIQHENIFPSPRELEGPVYSRGG 694
Query: 366 QKNDPKKAPVARSSVGWDATEDL 388
D +P ++ D+T+D+
Sbjct: 695 SMEDYCDSPHGETTSVEDSTQDV 717
>gi|112363096 SLIT-ROBO Rho GTPase activating protein 2 isoform b
[Homo sapiens]
Length = 836
Score = 92.4 bits (228), Expect = 1e-18
Identities = 70/263 (26%), Positives = 116/263 (44%), Gaps = 13/263 (4%)
Query: 131 LMASSQAEMEEWVKFLRRVAGTPCGVFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEH 190
L+ QA+ + K L T C + R TV + +P++VE C FI H
Sbjct: 463 LITKLQAKHDLLQKTLGESQRTDCSL--ARRSSTVRKQDS--SQAIPLVVESCIRFISRH 518
Query: 191 GRNEEGIFRLPGQDNLVKQLRDAFDAGERP--SFDRDTDVHTVASLLKLYLRDLPEPVVP 248
G EGIFR+ G V +++AF+ GE P D D+ ++A +LKLY R L P+ P
Sbjct: 519 GLQHEGIFRVSGSQVEVNDIKNAFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFP 578
Query: 249 WSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMS 308
+ + C + N E + K L +LP+ ++ Y+ FL+ + N M
Sbjct: 579 KDIFHDLMACVTMDNLQERAL--HIRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMD 636
Query: 309 VDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLFPKSKDIP---LSPPA 365
NLA G +L+ V + + ++ +I HE +FP +++ S
Sbjct: 637 PYNLAICFGPSLMSVPEGHDQVSCQA--HVNELIKTIIIQHENIFPSPRELEGPVYSRGG 694
Query: 366 QKNDPKKAPVARSSVGWDATEDL 388
D +P ++ D+T+D+
Sbjct: 695 SMEDYCDSPHGETTSVEDSTQDV 717
>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
Length = 1958
Score = 91.7 bits (226), Expect = 2e-18
Identities = 66/274 (24%), Positives = 124/274 (45%), Gaps = 11/274 (4%)
Query: 152 TPCGVFGQRLDETV-AYEQKFGPHLVPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQL 210
T G FG RLD+ A+ ++ +P++V+ C + + E G GI+R+PG + + +
Sbjct: 1140 TATGTFGVRLDDCPPAHTNRY----IPLIVDICCKLVEERGLEYTGIYRVPGNNAAISSM 1195
Query: 211 RDAFDAGERP---SFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEA 267
++ + G D+ D++ ++SLLK + R LPEP+ +Y F+ + D
Sbjct: 1196 QEELNKGMADIDIQDDKWRDLNVISSLLKSFFRKLPEPLFTNDKYADFIEANR--KEDPL 1253
Query: 268 KAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMSVDNLATVIGVNLIRSKVED 327
+ L + + LP +Y L ++ L + N NKM NLA V G L+R+ ++
Sbjct: 1254 DRLKTLKRLIHDLPEHHYETLKFLSAHLKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDN 1313
Query: 328 PAVIMRGTPQIQRVMTMMIRDHEVLF-PKSKDIPLSPPAQKNDPKKAPVARSSVGWDATE 386
++ P +++ +I+ H+ F + + PL+ +++ PV
Sbjct: 1314 MTHMVTHMPDQYKIVETLIQHHDWFFTEEGAEEPLTTVQEESTVDSQPVPNIDHLLTNIG 1373
Query: 387 DLRISRTDSFSSMTSDSDTTSPTGQQPSDAFPED 420
+S D S TSDS + + D + +
Sbjct: 1374 RTGVSPGDVSDSATSDSTKSKGSWGSGKDQYSRE 1407
Score = 33.5 bits (75), Expect = 0.62
Identities = 19/49 (38%), Positives = 24/49 (48%), Gaps = 11/49 (22%)
Query: 49 KMGWL----------KKQRSIVKNWQQRYFVLRAQQLYYYKDE-EDTKP 86
K GWL K+ ++ W+Q Y VLR LY YKD+ E T P
Sbjct: 934 KEGWLHFRPLVTDKGKRVGGSIRPWKQMYVVLRGHSLYLYKDKREQTTP 982
>gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo
sapiens]
Length = 1085
Score = 89.7 bits (221), Expect = 7e-18
Identities = 54/188 (28%), Positives = 95/188 (50%), Gaps = 8/188 (4%)
Query: 175 LVPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDT--DVHTVA 232
++P++VE C FI +G +GIFR+ G V ++++F+ GE P D + D+++VA
Sbjct: 518 VIPLIVESCIRFINLYGLQHQGIFRVSGSQVEVNDIKNSFERGENPLADDQSNHDINSVA 577
Query: 233 SLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYIC 292
+LKLY R L P+ P ++ + C ++ N E + K L LPR ++ Y+
Sbjct: 578 GVLKLYFRGLENPLFPKERFNDLISCIRIDNLYERAL--HIRKLLLTLPRSVLIVMRYLF 635
Query: 293 RFLHEIQLNCAVNKMSVDNLATVIGVNLIR-SKVEDPAVIMRGTPQIQRVMTMMIRDHEV 351
FL+ + N M NLA G L+ +++D + ++ +I HE
Sbjct: 636 AFLNHLSQYSDENMMDPYNLAICFGPTLMPVPEIQDQVSCQ---AHVNEIIKTIIIHHET 692
Query: 352 LFPKSKDI 359
+FP +K++
Sbjct: 693 IFPDAKEL 700
>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
Length = 818
Score = 89.7 bits (221), Expect = 7e-18
Identities = 61/206 (29%), Positives = 101/206 (49%), Gaps = 15/206 (7%)
Query: 136 QAEMEEWVKFLRRVAGTPCGVFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGRNEE 195
+A+ E WV+ P FG+ L+E + + + +E C +LE G EE
Sbjct: 241 KAQQEAWVE-------KPS--FGKPLEEHLTISGRE----IAFPIEACVTMLLECGMQEE 287
Query: 196 GIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGF 255
G+FR+ + +K+L+ A D + D H +A LK YLR+LPEP++ + Y+ +
Sbjct: 288 GLFRVAPSASKLKKLKAALDCCVVDVQEYSADPHAIAGALKSYLRELPEPLMTFELYDEW 347
Query: 256 LLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMSVDNLATV 315
+ + D K Q L LP+ N++ + Y+ +FL ++ VNKM+ N+A V
Sbjct: 348 IQASNVQEQD--KKLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIV 405
Query: 316 IGVNLIRSKVEDPAVIMRGTPQIQRV 341
+G NL+ + E M T +Q V
Sbjct: 406 LGPNLLWPQAEGNITEMMTTVSLQIV 431
>gi|75677374 SLIT-ROBO Rho GTPase activating protein 3 isoform b
[Homo sapiens]
Length = 1075
Score = 89.4 bits (220), Expect = 1e-17
Identities = 54/186 (29%), Positives = 96/186 (51%), Gaps = 6/186 (3%)
Query: 176 VPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFD--RDTDVHTVAS 233
+P++VE C +I +G ++GIFR+PG V ++++F+ GE P D + D+++VA
Sbjct: 495 IPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAG 554
Query: 234 LLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICR 293
+LKLY R L P+ P +++ + +L N A+ ++ + L LPR ++ Y+
Sbjct: 555 VLKLYFRGLENPLFPKERFQDLISTIKLEN--PAERVHQIQQILVTLPRVVIVVMRYLFA 612
Query: 294 FLHEIQLNCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLF 353
FL+ + N M NLA G L+ + D + I V+ +I HE +F
Sbjct: 613 FLNHLSQYSDENMMDPYNLAICFGPTLMH--IPDGQDPVSCQAHINEVIKTIIIHHEAIF 670
Query: 354 PKSKDI 359
P +++
Sbjct: 671 PSPREL 676
>gi|24307967 SLIT-ROBO Rho GTPase activating protein 3 isoform a
[Homo sapiens]
Length = 1099
Score = 89.4 bits (220), Expect = 1e-17
Identities = 54/186 (29%), Positives = 96/186 (51%), Gaps = 6/186 (3%)
Query: 176 VPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFD--RDTDVHTVAS 233
+P++VE C +I +G ++GIFR+PG V ++++F+ GE P D + D+++VA
Sbjct: 519 IPLVVESCIRYINLYGLQQQGIFRVPGSQVEVNDIKNSFERGEDPLVDDQNERDINSVAG 578
Query: 234 LLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICR 293
+LKLY R L P+ P +++ + +L N A+ ++ + L LPR ++ Y+
Sbjct: 579 VLKLYFRGLENPLFPKERFQDLISTIKLEN--PAERVHQIQQILVTLPRVVIVVMRYLFA 636
Query: 294 FLHEIQLNCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLF 353
FL+ + N M NLA G L+ + D + I V+ +I HE +F
Sbjct: 637 FLNHLSQYSDENMMDPYNLAICFGPTLMH--IPDGQDPVSCQAHINEVIKTIIIHHEAIF 694
Query: 354 PKSKDI 359
P +++
Sbjct: 695 PSPREL 700
>gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]
Length = 459
Score = 89.0 bits (219), Expect = 1e-17
Identities = 53/180 (29%), Positives = 95/180 (52%), Gaps = 5/180 (2%)
Query: 177 PILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDA-GERP--SFDRDTDVHTVAS 233
P++V+ C I G N EG++R+ G +L++ ++ AFD GE+ S + D++ +
Sbjct: 282 PMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITG 341
Query: 234 LLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICR 293
LKLY RDLP P++ + Y F+ ++ + DE + L + L +LP + L Y+
Sbjct: 342 ALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQL--ETLHEALKLLPPAHCETLRYLMA 399
Query: 294 FLHEIQLNCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLF 353
L + L+ N M+ +NL V G L+RS D + + V+ ++I++ ++LF
Sbjct: 400 HLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 459
>gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]
Length = 433
Score = 89.0 bits (219), Expect = 1e-17
Identities = 53/180 (29%), Positives = 95/180 (52%), Gaps = 5/180 (2%)
Query: 177 PILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDA-GERP--SFDRDTDVHTVAS 233
P++V+ C I G N EG++R+ G +L++ ++ AFD GE+ S + D++ +
Sbjct: 256 PMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITG 315
Query: 234 LLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICR 293
LKLY RDLP P++ + Y F+ ++ + DE + L + L +LP + L Y+
Sbjct: 316 ALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQL--ETLHEALKLLPPAHCETLRYLMA 373
Query: 294 FLHEIQLNCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLF 353
L + L+ N M+ +NL V G L+RS D + + V+ ++I++ ++LF
Sbjct: 374 HLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 433
>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
Length = 701
Score = 88.6 bits (218), Expect = 2e-17
Identities = 57/184 (30%), Positives = 94/184 (51%), Gaps = 7/184 (3%)
Query: 176 VPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASLL 235
+ + +E C +L G EEG+FRL +++K+L+ + + +D H VA L
Sbjct: 289 IALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASDPHSLEEFCSDPHAVAGAL 348
Query: 236 KLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRFL 295
K YLR+LPEP++ + Y+ ++ L + Q L + S LP +N S L Y+ +FL
Sbjct: 349 KSYLRELPEPLMTFDLYDDWMRAASL--KEPGARLQALQEVCSRLPPENLSNLRYLMKFL 406
Query: 296 HEIQLNCAVNKMSVDNLATVIGVNLI--RSKVEDPAVIMRGTP---QIQRVMTMMIRDHE 350
+ VNKM+ N+A V+G NL+ K D A + + Q+ V+ +I+ +
Sbjct: 407 ARLAEEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDAASVSSIQVVGVVEALIQSAD 466
Query: 351 VLFP 354
LFP
Sbjct: 467 TLFP 470
>gi|156142190 hypothetical protein LOC51306 isoform 2 [Homo sapiens]
Length = 887
Score = 88.2 bits (217), Expect = 2e-17
Identities = 66/207 (31%), Positives = 111/207 (53%), Gaps = 13/207 (6%)
Query: 156 VFGQRLDETVAYEQKFGP-HLVPILVEKCAEFILEHGRNEE-GIFRLPGQDNLVKQLRDA 213
+FG LDE +Q P + VP +V ++I EHG E+ G+F++ G V+ LR
Sbjct: 20 IFGIPLDEL---QQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQR 76
Query: 214 FDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQEL 273
+D+GE ++ DV + SLL+ +L++LPEPV+P S + + Q N +E + ++L
Sbjct: 77 YDSGEEVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQLSQDYN-NEDEFGRKL 135
Query: 274 MKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMSVDNLATVIGVNL--IRSKVEDPAVI 331
L LP NYSLL ++CRFL + + S ++LA V G ++ I + VED
Sbjct: 136 RFLLQQLPPVNYSLLKFLCRFLANVASH-HEEIWSANSLAAVFGPDVFHIYTDVED---- 190
Query: 332 MRGTPQIQRVMTMMIRDHEVLFPKSKD 358
M+ + R+M ++ ++ F ++
Sbjct: 191 MKEQEIVSRIMAGLLENYYEFFENEEE 217
>gi|156142188 hypothetical protein LOC51306 isoform 1 [Homo sapiens]
Length = 915
Score = 88.2 bits (217), Expect = 2e-17
Identities = 66/207 (31%), Positives = 111/207 (53%), Gaps = 13/207 (6%)
Query: 156 VFGQRLDETVAYEQKFGP-HLVPILVEKCAEFILEHGRNEE-GIFRLPGQDNLVKQLRDA 213
+FG LDE +Q P + VP +V ++I EHG E+ G+F++ G V+ LR
Sbjct: 20 IFGIPLDEL---QQGGHPDNEVPFIVRHVVDYIEEHGGLEQQGLFQVNGNAETVEWLRQR 76
Query: 214 FDAGERPSFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQEL 273
+D+GE ++ DV + SLL+ +L++LPEPV+P S + + Q N +E + ++L
Sbjct: 77 YDSGEEVDLVKEADVPSAISLLRFFLQELPEPVIPGSLHIHLMQLSQDYN-NEDEFGRKL 135
Query: 274 MKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMSVDNLATVIGVNL--IRSKVEDPAVI 331
L LP NYSLL ++CRFL + + S ++LA V G ++ I + VED
Sbjct: 136 RFLLQQLPPVNYSLLKFLCRFLANVASH-HEEIWSANSLAAVFGPDVFHIYTDVED---- 190
Query: 332 MRGTPQIQRVMTMMIRDHEVLFPKSKD 358
M+ + R+M ++ ++ F ++
Sbjct: 191 MKEQEIVSRIMAGLLENYYEFFENEEE 217
>gi|224458284 Rho GTPase activating protein 23 [Homo sapiens]
Length = 1397
Score = 86.7 bits (213), Expect = 6e-17
Identities = 58/221 (26%), Positives = 102/221 (46%), Gaps = 8/221 (3%)
Query: 157 FGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDA 216
FG RL+E + VP++V C + G GI+R+PG + +V L++ +
Sbjct: 809 FGVRLEECQPATEN---QRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNR 865
Query: 217 GERP---SFDRDTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQEL 273
G +R D++ ++SLLK + R LPEP+ +Y F+ ++ +A E + L
Sbjct: 866 GPGDINLQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARER--MRTL 923
Query: 274 MKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMR 333
K + LP Y L ++ L I + NKM NLA V G L+R+ ++ ++
Sbjct: 924 RKLIRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVT 983
Query: 334 GTPQIQRVMTMMIRDHEVLFPKSKDIPLSPPAQKNDPKKAP 374
P +++ +I+ + F +D P +P+ P
Sbjct: 984 HMPDRYKIVETLIQHSDWFFSDEEDKGERTPVGDKEPQAVP 1024
>gi|4757980 beta chimerin isoform 2 [Homo sapiens]
Length = 468
Score = 86.7 bits (213), Expect = 6e-17
Identities = 51/180 (28%), Positives = 93/180 (51%), Gaps = 5/180 (2%)
Query: 177 PILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDA-GERPSFDRDT--DVHTVAS 233
P++V+ C I G EG++R+ G ++ ++ AFD GE+ + D++ +
Sbjct: 291 PMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITG 350
Query: 234 LLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICR 293
LKLY RDLP PV+ + Y F+ +++NADE + + + L +LP +Y L Y+
Sbjct: 351 ALKLYFRDLPIPVITYDTYSKFIDAAKISNADE--RLEAVHEVLMLLPPAHYETLRYLMI 408
Query: 294 FLHEIQLNCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLF 353
L ++ +N N M+ +NL V G L+R + + + ++ ++I + +VLF
Sbjct: 409 HLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 468
>gi|91106928 beta chimerin isoform 1 [Homo sapiens]
Length = 332
Score = 86.7 bits (213), Expect = 6e-17
Identities = 51/180 (28%), Positives = 93/180 (51%), Gaps = 5/180 (2%)
Query: 177 PILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDA-GERPSFDRDT--DVHTVAS 233
P++V+ C I G EG++R+ G ++ ++ AFD GE+ + D++ +
Sbjct: 155 PMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADISANVYPDINIITG 214
Query: 234 LLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICR 293
LKLY RDLP PV+ + Y F+ +++NADE + + + L +LP +Y L Y+
Sbjct: 215 ALKLYFRDLPIPVITYDTYSKFIDAAKISNADE--RLEAVHEVLMLLPPAHYETLRYLMI 272
Query: 294 FLHEIQLNCAVNKMSVDNLATVIGVNLIRSKVEDPAVIMRGTPQIQRVMTMMIRDHEVLF 353
L ++ +N N M+ +NL V G L+R + + + ++ ++I + +VLF
Sbjct: 273 HLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENEDVLF 332
>gi|229094128 active breakpoint cluster region-related protein
isoform c [Homo sapiens]
Length = 813
Score = 85.5 bits (210), Expect = 1e-16
Identities = 58/178 (32%), Positives = 89/178 (50%), Gaps = 9/178 (5%)
Query: 155 GVFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAF 214
GVFG ++ E+ VP +V +C E + + G E GI+R+ G ++ L+ F
Sbjct: 597 GVFGVKISVVTKRERS----KVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVF 652
Query: 215 DAGERPSFDR--DTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQE 272
DA + D D++ +A LKLY R+LPEP++ Y F+ + +D A +
Sbjct: 653 DANNKDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFM--EGIALSDPAAKENC 710
Query: 273 LMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMSVDNLATVIGVNLIR-SKVEDPA 329
+M L LP N ++ L + +NKMS+ NLATV G L+R S+VE A
Sbjct: 711 MMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKA 768
>gi|38679957 active breakpoint cluster region-related protein
isoform a [Homo sapiens]
Length = 859
Score = 85.5 bits (210), Expect = 1e-16
Identities = 58/178 (32%), Positives = 89/178 (50%), Gaps = 9/178 (5%)
Query: 155 GVFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAF 214
GVFG ++ E+ VP +V +C E + + G E GI+R+ G ++ L+ F
Sbjct: 643 GVFGVKISVVTKRERS----KVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVF 698
Query: 215 DAGERPSFDR--DTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQE 272
DA + D D++ +A LKLY R+LPEP++ Y F+ + +D A +
Sbjct: 699 DANNKDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFM--EGIALSDPAAKENC 756
Query: 273 LMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMSVDNLATVIGVNLIR-SKVEDPA 329
+M L LP N ++ L + +NKMS+ NLATV G L+R S+VE A
Sbjct: 757 MMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKA 814
>gi|38679954 active breakpoint cluster region-related protein
isoform b [Homo sapiens]
Length = 822
Score = 85.5 bits (210), Expect = 1e-16
Identities = 58/178 (32%), Positives = 89/178 (50%), Gaps = 9/178 (5%)
Query: 155 GVFGQRLDETVAYEQKFGPHLVPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAF 214
GVFG ++ E+ VP +V +C E + + G E GI+R+ G ++ L+ F
Sbjct: 606 GVFGVKISVVTKRERS----KVPYIVRQCVEEVEKRGIEEVGIYRISGVATDIQALKAVF 661
Query: 215 DAGERPSFDR--DTDVHTVASLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQE 272
DA + D D++ +A LKLY R+LPEP++ Y F+ + +D A +
Sbjct: 662 DANNKDILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFM--EGIALSDPAAKENC 719
Query: 273 LMKQLSILPRDNYSLLSYICRFLHEIQLNCAVNKMSVDNLATVIGVNLIR-SKVEDPA 329
+M L LP N ++ L + +NKMS+ NLATV G L+R S+VE A
Sbjct: 720 MMHLLRSLPDPNLITFLFLLEHLKRVAEKEPINKMSLHNLATVFGPTLLRPSEVESKA 777
>gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]
Length = 1444
Score = 85.5 bits (210), Expect = 1e-16
Identities = 53/152 (34%), Positives = 79/152 (51%), Gaps = 6/152 (3%)
Query: 176 VPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDT---DVHTVA 232
VP +++ CAEFI HG +GI+RL G + +++LR F + + P R+ D+H V
Sbjct: 34 VPYVLKSCAEFIETHGI-VDGIYRLSGVTSNIQRLRQEFGSDQCPDLTREVYLQDIHCVG 92
Query: 233 SLLKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYIC 292
SL KLY R+LP P++ + YE F +++ E + + LP +Y L Y+
Sbjct: 93 SLCKLYFRELPNPLLTYELYEKF--TEAVSHCPEEGQLARIQNVIQELPPSHYRTLEYLI 150
Query: 293 RFLHEIQLNCAVNKMSVDNLATVIGVNLIRSK 324
R L I + M NLA V NL+RSK
Sbjct: 151 RHLAHIASFSSKTNMHARNLALVWAPNLLRSK 182
>gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens]
Length = 555
Score = 85.1 bits (209), Expect = 2e-16
Identities = 47/147 (31%), Positives = 78/147 (53%), Gaps = 3/147 (2%)
Query: 175 LVPILVEKCAEFILEHGRNEEGIFRLPGQDNLVKQLRDAFDAGERPSFDRDTDVHTVASL 234
L+P ++ ++ E G EG+FR V++++ ++ G+ +FD D+H A +
Sbjct: 330 LIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVI 389
Query: 235 LKLYLRDLPEPVVPWSQYEGFLLCGQLTNADEAKAQQELMKQLSILPRDNYSLLSYICRF 294
LK +LR+LP+P++ + YE L +T + + + L LP NY +L Y+ F
Sbjct: 390 LKTFLRELPQPLLTFQAYEQIL---GITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGF 446
Query: 295 LHEIQLNCAVNKMSVDNLATVIGVNLI 321
LH + NKM+ NLA V G+NLI
Sbjct: 447 LHAVSRESIFNKMNSSNLACVFGLNLI 473
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.129 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,603,255
Number of Sequences: 37866
Number of extensions: 1244069
Number of successful extensions: 10237
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 444
Number of HSP's successfully gapped in prelim test: 778
Number of HSP's that attempted gapping in prelim test: 5893
Number of HSP's gapped (non-prelim): 4318
length of query: 645
length of database: 18,247,518
effective HSP length: 109
effective length of query: 536
effective length of database: 14,120,124
effective search space: 7568386464
effective search space used: 7568386464
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.