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Search of human proteins with 55770846
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55770846 catenin, alpha 2 [Homo sapiens]
(905 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55770846 catenin, alpha 2 [Homo sapiens] 1736 0.0
gi|55770844 catenin, alpha 1 [Homo sapiens] 1434 0.0
gi|188497718 catenin, alpha 3 [Homo sapiens] 1077 0.0
gi|188497716 catenin, alpha 3 [Homo sapiens] 1077 0.0
gi|4503129 catenin, alpha-like 1 [Homo sapiens] 201 2e-51
gi|4507877 vinculin isoform VCL [Homo sapiens] 191 2e-48
gi|7669550 vinculin isoform meta-VCL [Homo sapiens] 135 1e-31
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 47 8e-05
gi|118498362 kinectin 1 isoform b [Homo sapiens] 45 3e-04
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 44 5e-04
gi|118498356 kinectin 1 isoform a [Homo sapiens] 44 7e-04
gi|118498368 kinectin 1 isoform c [Homo sapiens] 44 7e-04
gi|33620775 kinectin 1 isoform a [Homo sapiens] 44 7e-04
gi|58530840 desmoplakin isoform I [Homo sapiens] 44 9e-04
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 44 9e-04
gi|169207319 PREDICTED: hypothetical protein [Homo sapiens] 41 0.004
gi|169207756 PREDICTED: hypothetical protein [Homo sapiens] 41 0.004
gi|169207046 PREDICTED: hypothetical protein [Homo sapiens] 41 0.004
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 41 0.006
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 40 0.008
gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 40 0.010
gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens] 40 0.010
gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 40 0.010
gi|223029410 talin 1 [Homo sapiens] 38 0.037
gi|71061468 centromere protein E [Homo sapiens] 37 0.064
gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 37 0.11
gi|110347568 centrosomal protein 152kDa [Homo sapiens] 36 0.19
gi|134152674 rabaptin, RAB GTPase binding effector protein 1 iso... 36 0.19
gi|31377798 rabaptin, RAB GTPase binding effector protein 1 isof... 36 0.19
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 35 0.24
>gi|55770846 catenin, alpha 2 [Homo sapiens]
Length = 905
Score = 1736 bits (4497), Expect = 0.0
Identities = 905/905 (100%), Positives = 905/905 (100%)
Query: 1 MTSATSPIILKWDPKSLEIRTLTVERLLEPLVTQVTTLVNTSNKGPSGKKKGRSKKAHVL 60
MTSATSPIILKWDPKSLEIRTLTVERLLEPLVTQVTTLVNTSNKGPSGKKKGRSKKAHVL
Sbjct: 1 MTSATSPIILKWDPKSLEIRTLTVERLLEPLVTQVTTLVNTSNKGPSGKKKGRSKKAHVL 60
Query: 61 AASVEQATQNFLEKGEQIAKESQDLKEELVAAVEDVRKQGETMRIASSEFADDPCSSVKR 120
AASVEQATQNFLEKGEQIAKESQDLKEELVAAVEDVRKQGETMRIASSEFADDPCSSVKR
Sbjct: 61 AASVEQATQNFLEKGEQIAKESQDLKEELVAAVEDVRKQGETMRIASSEFADDPCSSVKR 120
Query: 121 GTMVRAARALLSAVTRLLILADMADVMRLLSHLKIVEEALEAVKNATNEQDLANRFKEFG 180
GTMVRAARALLSAVTRLLILADMADVMRLLSHLKIVEEALEAVKNATNEQDLANRFKEFG
Sbjct: 121 GTMVRAARALLSAVTRLLILADMADVMRLLSHLKIVEEALEAVKNATNEQDLANRFKEFG 180
Query: 181 KEMVKLNYVAARRQQELKDPHCRDEMAAARGALKKNATMLYTASQAFLRHPDVAATRANR 240
KEMVKLNYVAARRQQELKDPHCRDEMAAARGALKKNATMLYTASQAFLRHPDVAATRANR
Sbjct: 181 KEMVKLNYVAARRQQELKDPHCRDEMAAARGALKKNATMLYTASQAFLRHPDVAATRANR 240
Query: 241 DYVFKQVQEAIAGISNAAQATSPTDEAKGHTGIGELAAALNEFDNKIILDPMTFSEARFR 300
DYVFKQVQEAIAGISNAAQATSPTDEAKGHTGIGELAAALNEFDNKIILDPMTFSEARFR
Sbjct: 241 DYVFKQVQEAIAGISNAAQATSPTDEAKGHTGIGELAAALNEFDNKIILDPMTFSEARFR 300
Query: 301 PSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMNNTGRKEKGD 360
PSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMNNTGRKEKGD
Sbjct: 301 PSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMNNTGRKEKGD 360
Query: 361 PLNIAIDKMTKKTRDLRRQLRKAVMDHISDSFLETNVPLLVLIEAAKSGNEKEVKEYAQV 420
PLNIAIDKMTKKTRDLRRQLRKAVMDHISDSFLETNVPLLVLIEAAKSGNEKEVKEYAQV
Sbjct: 361 PLNIAIDKMTKKTRDLRRQLRKAVMDHISDSFLETNVPLLVLIEAAKSGNEKEVKEYAQV 420
Query: 421 FREHANKLVEVANLACSISNNEEGVKLVRMAATQIDSLCPQVINAALTLAARPQSKVAQD 480
FREHANKLVEVANLACSISNNEEGVKLVRMAATQIDSLCPQVINAALTLAARPQSKVAQD
Sbjct: 421 FREHANKLVEVANLACSISNNEEGVKLVRMAATQIDSLCPQVINAALTLAARPQSKVAQD 480
Query: 481 NMDVFKDQWEKQVRVLTEAVDDITSVDDFLSVSENHILEDVNKCVIALQEGDVDTLDRTA 540
NMDVFKDQWEKQVRVLTEAVDDITSVDDFLSVSENHILEDVNKCVIALQEGDVDTLDRTA
Sbjct: 481 NMDVFKDQWEKQVRVLTEAVDDITSVDDFLSVSENHILEDVNKCVIALQEGDVDTLDRTA 540
Query: 541 GAIRGRAARVIHIINAEMENYEAGVYTEKVLEATKLLSETVMPRFAEQVEVAIEALSANV 600
GAIRGRAARVIHIINAEMENYEAGVYTEKVLEATKLLSETVMPRFAEQVEVAIEALSANV
Sbjct: 541 GAIRGRAARVIHIINAEMENYEAGVYTEKVLEATKLLSETVMPRFAEQVEVAIEALSANV 600
Query: 601 PQPFEENEFIDASRLVYDGVRDIRKAVLMIRTPEELEDDSDFEQEDYDVRSRTSVQTEDD 660
PQPFEENEFIDASRLVYDGVRDIRKAVLMIRTPEELEDDSDFEQEDYDVRSRTSVQTEDD
Sbjct: 601 PQPFEENEFIDASRLVYDGVRDIRKAVLMIRTPEELEDDSDFEQEDYDVRSRTSVQTEDD 660
Query: 661 QLIAGQSARAIMAQLPQEEKAKIAEQVEIFHQEKSKLDAEVAKWDDSGNDIIVLAKQMCM 720
QLIAGQSARAIMAQLPQEEKAKIAEQVEIFHQEKSKLDAEVAKWDDSGNDIIVLAKQMCM
Sbjct: 661 QLIAGQSARAIMAQLPQEEKAKIAEQVEIFHQEKSKLDAEVAKWDDSGNDIIVLAKQMCM 720
Query: 721 IMMEMTDFTRGKGPLKNTSDVINAAKKIAEAGSRMDKLARAVADQCPDSACKQDLLAYLQ 780
IMMEMTDFTRGKGPLKNTSDVINAAKKIAEAGSRMDKLARAVADQCPDSACKQDLLAYLQ
Sbjct: 721 IMMEMTDFTRGKGPLKNTSDVINAAKKIAEAGSRMDKLARAVADQCPDSACKQDLLAYLQ 780
Query: 781 RIALYCHQLNICSKVKAEVQNLGGELIVSGLDSATSLIQAAKNLMNAVVLTVKASYVAST 840
RIALYCHQLNICSKVKAEVQNLGGELIVSGLDSATSLIQAAKNLMNAVVLTVKASYVAST
Sbjct: 781 RIALYCHQLNICSKVKAEVQNLGGELIVSGLDSATSLIQAAKNLMNAVVLTVKASYVAST 840
Query: 841 KYQKVYGTAAVNSPVVSWKMKAPEKKPLVKREKPEEFQTRVRRGSQKKHISPVQALSEFK 900
KYQKVYGTAAVNSPVVSWKMKAPEKKPLVKREKPEEFQTRVRRGSQKKHISPVQALSEFK
Sbjct: 841 KYQKVYGTAAVNSPVVSWKMKAPEKKPLVKREKPEEFQTRVRRGSQKKHISPVQALSEFK 900
Query: 901 AMDSF 905
AMDSF
Sbjct: 901 AMDSF 905
>gi|55770844 catenin, alpha 1 [Homo sapiens]
Length = 906
Score = 1434 bits (3712), Expect = 0.0
Identities = 741/899 (82%), Positives = 820/899 (91%), Gaps = 4/899 (0%)
Query: 8 IILKWDPKSLEIRTLTVERLLEPLVTQVTTLVNTSNKGPSGKKKGRSKKAHVLAASVEQA 67
I KWDPKSLEIRTL VERLLEPLVTQVTTLVNT++KGPS KK+GRSKKAHVLAASVEQA
Sbjct: 9 INFKWDPKSLEIRTLAVERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKAHVLAASVEQA 68
Query: 68 TQNFLEKGEQIAKESQDLKEELVAAVEDVRKQGETMRIASSEFADDPCSSVKRGTMVRAA 127
T+NFLEKG++IAKESQ LKEELVAAVEDVRKQG+ M+ A+ EFADDPCSSVKRG MVRAA
Sbjct: 69 TENFLEKGDKIAKESQFLKEELVAAVEDVRKQGDLMKAAAGEFADDPCSSVKRGNMVRAA 128
Query: 128 RALLSAVTRLLILADMADVMRLLSHLKIVEEALEAVKNATNEQDLANRFKEFGKEMVKLN 187
RALLSAVTRLLILADMADV +LL LK+VE+ + ++NA NEQDL ++K E+ KLN
Sbjct: 129 RALLSAVTRLLILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYKALKPEVDKLN 188
Query: 188 YVAARRQQELKDPHCRDEMAAARGALKKNATMLYTASQAFLRHPDVAATRANRDYVFKQV 247
+AA+RQQELKD RD+MAAARG L+KN +LYTASQA L+HPDVAA +ANRD ++KQ+
Sbjct: 189 IMAAKRQQELKDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKANRDLIYKQL 248
Query: 248 QEAIAGISNAAQATSPTDEAKGHTGIG--ELAAALNEFDNKIILDPMTFSEARFRPSLEE 305
Q+A+ GISNAAQAT+ +D+A H G G ELA ALN FD +II+DP++FSE RFRPSLEE
Sbjct: 249 QQAVTGISNAAQATA-SDDASQHQGGGGGELAYALNNFDKQIIVDPLSFSEERFRPSLEE 307
Query: 306 RLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMNNTGRKEKGDPLNIA 365
RLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYM N GRKE+ D LN A
Sbjct: 308 RLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMGNAGRKERSDALNSA 367
Query: 366 IDKMTKKTRDLRRQLRKAVMDHISDSFLETNVPLLVLIEAAKSGNEKEVKEYAQVFREHA 425
IDKMTKKTRDLRRQLRKAVMDH+SDSFLETNVPLLVLIEAAK+GNEKEVKEYAQVFREHA
Sbjct: 368 IDKMTKKTRDLRRQLRKAVMDHVSDSFLETNVPLLVLIEAAKNGNEKEVKEYAQVFREHA 427
Query: 426 NKLVEVANLACSISNNEEGVKLVRMAATQIDSLCPQVINAALTLAARPQSKVAQDNMDVF 485
NKL+EVANLACSISNNEEGVKLVRM+A+Q+++LCPQVINAAL LAA+PQSK+AQ+NMD+F
Sbjct: 428 NKLIEVANLACSISNNEEGVKLVRMSASQLEALCPQVINAALALAAKPQSKLAQENMDLF 487
Query: 486 KDQWEKQVRVLTEAVDDITSVDDFLSVSENHILEDVNKCVIALQEGDVDTLDRTAGAIRG 545
K+QWEKQVRVLT+AVDDITS+DDFL+VSENHILEDVNKCVIALQE DVD LDRTAGAIRG
Sbjct: 488 KEQWEKQVRVLTDAVDDITSIDDFLAVSENHILEDVNKCVIALQEKDVDGLDRTAGAIRG 547
Query: 546 RAARVIHIINAEMENYEAGVYTEKVLEATKLLSETVMPRFAEQVEVAIEALSANVPQPFE 605
RAARVIH++ +EM+NYE GVYTEKVLEATKLLS TVMPRF EQVE A+EALS++ QP +
Sbjct: 548 RAARVIHVVTSEMDNYEPGVYTEKVLEATKLLSNTVMPRFTEQVEAAVEALSSDPAQPMD 607
Query: 606 ENEFIDASRLVYDGVRDIRKAVLMIRTPEELEDDSDFEQEDYDVRSRTSVQTEDDQLIAG 665
ENEFIDASRLVYDG+RDIRKAVLMIRTPEEL DDSDFE ED+DVRSRTSVQTEDDQLIAG
Sbjct: 608 ENEFIDASRLVYDGIRDIRKAVLMIRTPEEL-DDSDFETEDFDVRSRTSVQTEDDQLIAG 666
Query: 666 QSARAIMAQLPQEEKAKIAEQVEIFHQEKSKLDAEVAKWDDSGNDIIVLAKQMCMIMMEM 725
QSARAIMAQLPQE+KAKIAEQV F +EKSKLDAEV+KWDDSGNDIIVLAKQMCMIMMEM
Sbjct: 667 QSARAIMAQLPQEQKAKIAEQVASFQEEKSKLDAEVSKWDDSGNDIIVLAKQMCMIMMEM 726
Query: 726 TDFTRGKGPLKNTSDVINAAKKIAEAGSRMDKLARAVADQCPDSACKQDLLAYLQRIALY 785
TDFTRGKGPLKNTSDVI+AAKKIAEAGSRMDKL R +AD CPDSACKQDLLAYLQRIALY
Sbjct: 727 TDFTRGKGPLKNTSDVISAAKKIAEAGSRMDKLGRTIADHCPDSACKQDLLAYLQRIALY 786
Query: 786 CHQLNICSKVKAEVQNLGGELIVSGLDSATSLIQAAKNLMNAVVLTVKASYVASTKYQKV 845
CHQLNICSKVKAEVQNLGGEL+VSG+DSA SLIQAAKNLMNAVV TVKASYVASTKYQK
Sbjct: 787 CHQLNICSKVKAEVQNLGGELVVSGVDSAMSLIQAAKNLMNAVVQTVKASYVASTKYQKS 846
Query: 846 YGTAAVNSPVVSWKMKAPEKKPLVKREKPEEFQTRVRRGSQKKHISPVQALSEFKAMDS 904
G A++N P VSWKMKAPEKKPLVKREK +E QT+++R SQKKH++PVQALSEFKAMDS
Sbjct: 847 QGMASLNLPAVSWKMKAPEKKPLVKREKQDETQTKIKRASQKKHVNPVQALSEFKAMDS 905
>gi|188497718 catenin, alpha 3 [Homo sapiens]
Length = 895
Score = 1077 bits (2784), Expect = 0.0
Identities = 549/903 (60%), Positives = 704/903 (77%), Gaps = 19/903 (2%)
Query: 3 SATSPIILKWDPKSLEIRTLTVERLLEPLVTQVTTLVNTSNKGPSGKKKGRSKKAHVLAA 62
SA +PI L DP+ L+++T TVE+LLEPL+ QVTTLVN + PS +KKGRSK+A VL A
Sbjct: 2 SAETPITLNIDPQDLQVQTFTVEKLLEPLIIQVTTLVNCP-QNPSSRKKGRSKRASVLLA 60
Query: 63 SVEQATQNFLEKGEQIAKESQDLKEELVAAVEDVRKQGETMRIASSEFADDPCSSVKRGT 122
SVE+AT N L+KGE+IA+E+ LK+EL A++E+VRK+ E +++++ F DDPC KR
Sbjct: 61 SVEEATWNLLDKGEKIAQEATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKREA 120
Query: 123 MVRAARALLSAVTRLLILADMADVMRLLSHLKIVEEALEAVKNATNEQDLANRFKEFGKE 182
+V+AARALL+AVTRLLILADM DVM LL H+ + E++KN N+ DL +++ GKE
Sbjct: 121 VVQAARALLAAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKLGKE 180
Query: 183 MVKLNYVAARRQQELKDPHCRDEMAAARGALKKNATMLYTASQAFLRHPDVAATRANRDY 242
+ L+Y+A +RQQ+LK P+ RDE+A AR +LK+N+ +L++ A L H DVA+ +A++D
Sbjct: 181 LENLDYLAFKRQQDLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDT 240
Query: 243 VFKQVQEAIAGISNAAQA-----TSPTDEAKGHTGIGELAAALNEFDNKIILDPMTFSEA 297
V +++Q A+ ISNA+Q T P +A L +AL+E +N I+L+P+T +E
Sbjct: 241 VCEEIQNALNVISNASQGIQNMTTPPEPQA------ATLGSALDELENLIVLNPLTVTEE 294
Query: 298 RFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMNNTGRKE 357
RPSLE+RLE+IISGAAL+ADSSCTRD RERI+AECNA+RQALQDLLSEYMNN G+KE
Sbjct: 295 EIRPSLEKRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMNNAGKKE 354
Query: 358 KGDPLNIAIDKMTKKTRDLRRQLRKAVMDHISDSFLETNVPLLVLIEAAKSGNEKEVKEY 417
+ + LNIA+D M KKTRDLRRQLRKA++DH+SDSFL+T VPLLVLIEAAK+G EKE+KEY
Sbjct: 355 RSNTLNIALDNMCKKTRDLRRQLRKAIIDHVSDSFLDTTVPLLVLIEAAKNGREKEIKEY 414
Query: 418 AQVFREHANKLVEVANLACSISNNEEGVKLVRMAATQIDSLCPQVINAALTLAARPQSKV 477
A +F EH ++LVEVANLACS+S NE+G+K+V++AA +++LCPQ+INAAL LAARP+S+
Sbjct: 415 AAIFHEHTSRLVEVANLACSMSTNEDGIKIVKIAANHLETLCPQIINAALALAARPKSQA 474
Query: 478 AQDNMDVFKDQWEKQVRVLTEAVDDITSVDDFLSVSENHILEDVNKCVIALQEGDVDTLD 537
++ M+++K WE + VLTEAVDDITS+DDFL+VSE+HILEDVNKC+IAL++ D D LD
Sbjct: 475 VKNTMEMYKRTWENHIHVLTEAVDDITSIDDFLAVSESHILEDVNKCIIALRDQDADNLD 534
Query: 538 RTAGAIRGRAARVIHIINAEMENYEAGVYTEKVLEATKLLSETVMPRFAEQVEVAIEALS 597
R AGAIRGRAARV HI+ EM++YE G YTE V+ L+ TV+P F QV VA+EALS
Sbjct: 535 RAAGAIRGRAARVAHIVTGEMDSYEPGAYTEGVMRNVNFLTSTVIPEFVTQVNVALEALS 594
Query: 598 ANVPQPFEENEFIDASRLVYDGVRDIRKAVLMIRTPEELEDDSDFEQEDYDVRSRTSVQT 657
+ ++N+F+D S+ +YD + DIR +V+MIRTPEELED SD E E+++VRS TS+QT
Sbjct: 595 KSSLNVLDDNQFVDISKKIYDTIHDIRCSVMMIRTPEELEDVSDLE-EEHEVRSHTSIQT 653
Query: 658 EDDQLIAGQSARAIMAQLPQEEKAKIAEQVEIFHQEKSKLDAEVAKWDDSGNDIIVLAKQ 717
E G++ RA M QLP+ EK KIAEQV F + KSKLDAE+ WDD+ NDIIVLAK
Sbjct: 654 E------GKTDRAKMTQLPEAEKEKIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKN 707
Query: 718 MCMIMMEMTDFTRGKGPLKNTSDVINAAKKIAEAGSRMDKLARAVADQCPDSACKQDLLA 777
MCMIMMEMTDFTRGKGPLK+T+DVI AAK I+E+GSRMD LAR +A+QCPD +CKQDLLA
Sbjct: 708 MCMIMMEMTDFTRGKGPLKHTTDVIYAAKMISESGSRMDVLARQIANQCPDPSCKQDLLA 767
Query: 778 YLQRIALYCHQLNICSKVKAEVQNLGGELIVSGLDSATSLIQAAKNLMNAVVLTVKASYV 837
YL++I Y HQL ICS+VKAE+QNLGGELI+S LDS TSLIQAAKNLMNAVV TVK SY+
Sbjct: 768 YLEQIKFYSHQLKICSQVKAEIQNLGGELIMSALDSVTSLIQAAKNLMNAVVQTVKMSYI 827
Query: 838 ASTKYQKVYGTAAVNSPVVSWKMKAPEKKPLVKREKPEEFQTRVRRGSQKKHISPVQALS 897
ASTK ++ A PVV W+MKAP KKPL+KREKPEE VRRGS KK I P+Q +S
Sbjct: 828 ASTKIIRIQSPAGPRHPVVMWRMKAPAKKPLIKREKPEETCAAVRRGSAKKKIHPLQVMS 887
Query: 898 EFK 900
EF+
Sbjct: 888 EFR 890
>gi|188497716 catenin, alpha 3 [Homo sapiens]
Length = 895
Score = 1077 bits (2784), Expect = 0.0
Identities = 549/903 (60%), Positives = 704/903 (77%), Gaps = 19/903 (2%)
Query: 3 SATSPIILKWDPKSLEIRTLTVERLLEPLVTQVTTLVNTSNKGPSGKKKGRSKKAHVLAA 62
SA +PI L DP+ L+++T TVE+LLEPL+ QVTTLVN + PS +KKGRSK+A VL A
Sbjct: 2 SAETPITLNIDPQDLQVQTFTVEKLLEPLIIQVTTLVNCP-QNPSSRKKGRSKRASVLLA 60
Query: 63 SVEQATQNFLEKGEQIAKESQDLKEELVAAVEDVRKQGETMRIASSEFADDPCSSVKRGT 122
SVE+AT N L+KGE+IA+E+ LK+EL A++E+VRK+ E +++++ F DDPC KR
Sbjct: 61 SVEEATWNLLDKGEKIAQEATVLKDELTASLEEVRKESEALKVSAERFTDDPCFLPKREA 120
Query: 123 MVRAARALLSAVTRLLILADMADVMRLLSHLKIVEEALEAVKNATNEQDLANRFKEFGKE 182
+V+AARALL+AVTRLLILADM DVM LL H+ + E++KN N+ DL +++ GKE
Sbjct: 121 VVQAARALLAAVTRLLILADMIDVMCLLQHVSAFQRTFESLKNVANKSDLQKTYQKLGKE 180
Query: 183 MVKLNYVAARRQQELKDPHCRDEMAAARGALKKNATMLYTASQAFLRHPDVAATRANRDY 242
+ L+Y+A +RQQ+LK P+ RDE+A AR +LK+N+ +L++ A L H DVA+ +A++D
Sbjct: 181 LENLDYLAFKRQQDLKSPNQRDEIAGARASLKENSPLLHSICSACLEHSDVASLKASKDT 240
Query: 243 VFKQVQEAIAGISNAAQA-----TSPTDEAKGHTGIGELAAALNEFDNKIILDPMTFSEA 297
V +++Q A+ ISNA+Q T P +A L +AL+E +N I+L+P+T +E
Sbjct: 241 VCEEIQNALNVISNASQGIQNMTTPPEPQA------ATLGSALDELENLIVLNPLTVTEE 294
Query: 298 RFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMNNTGRKE 357
RPSLE+RLE+IISGAAL+ADSSCTRD RERI+AECNA+RQALQDLLSEYMNN G+KE
Sbjct: 295 EIRPSLEKRLEAIISGAALLADSSCTRDLHRERIIAECNAIRQALQDLLSEYMNNAGKKE 354
Query: 358 KGDPLNIAIDKMTKKTRDLRRQLRKAVMDHISDSFLETNVPLLVLIEAAKSGNEKEVKEY 417
+ + LNIA+D M KKTRDLRRQLRKA++DH+SDSFL+T VPLLVLIEAAK+G EKE+KEY
Sbjct: 355 RSNTLNIALDNMCKKTRDLRRQLRKAIIDHVSDSFLDTTVPLLVLIEAAKNGREKEIKEY 414
Query: 418 AQVFREHANKLVEVANLACSISNNEEGVKLVRMAATQIDSLCPQVINAALTLAARPQSKV 477
A +F EH ++LVEVANLACS+S NE+G+K+V++AA +++LCPQ+INAAL LAARP+S+
Sbjct: 415 AAIFHEHTSRLVEVANLACSMSTNEDGIKIVKIAANHLETLCPQIINAALALAARPKSQA 474
Query: 478 AQDNMDVFKDQWEKQVRVLTEAVDDITSVDDFLSVSENHILEDVNKCVIALQEGDVDTLD 537
++ M+++K WE + VLTEAVDDITS+DDFL+VSE+HILEDVNKC+IAL++ D D LD
Sbjct: 475 VKNTMEMYKRTWENHIHVLTEAVDDITSIDDFLAVSESHILEDVNKCIIALRDQDADNLD 534
Query: 538 RTAGAIRGRAARVIHIINAEMENYEAGVYTEKVLEATKLLSETVMPRFAEQVEVAIEALS 597
R AGAIRGRAARV HI+ EM++YE G YTE V+ L+ TV+P F QV VA+EALS
Sbjct: 535 RAAGAIRGRAARVAHIVTGEMDSYEPGAYTEGVMRNVNFLTSTVIPEFVTQVNVALEALS 594
Query: 598 ANVPQPFEENEFIDASRLVYDGVRDIRKAVLMIRTPEELEDDSDFEQEDYDVRSRTSVQT 657
+ ++N+F+D S+ +YD + DIR +V+MIRTPEELED SD E E+++VRS TS+QT
Sbjct: 595 KSSLNVLDDNQFVDISKKIYDTIHDIRCSVMMIRTPEELEDVSDLE-EEHEVRSHTSIQT 653
Query: 658 EDDQLIAGQSARAIMAQLPQEEKAKIAEQVEIFHQEKSKLDAEVAKWDDSGNDIIVLAKQ 717
E G++ RA M QLP+ EK KIAEQV F + KSKLDAE+ WDD+ NDIIVLAK
Sbjct: 654 E------GKTDRAKMTQLPEAEKEKIAEQVADFKKVKSKLDAEIEIWDDTSNDIIVLAKN 707
Query: 718 MCMIMMEMTDFTRGKGPLKNTSDVINAAKKIAEAGSRMDKLARAVADQCPDSACKQDLLA 777
MCMIMMEMTDFTRGKGPLK+T+DVI AAK I+E+GSRMD LAR +A+QCPD +CKQDLLA
Sbjct: 708 MCMIMMEMTDFTRGKGPLKHTTDVIYAAKMISESGSRMDVLARQIANQCPDPSCKQDLLA 767
Query: 778 YLQRIALYCHQLNICSKVKAEVQNLGGELIVSGLDSATSLIQAAKNLMNAVVLTVKASYV 837
YL++I Y HQL ICS+VKAE+QNLGGELI+S LDS TSLIQAAKNLMNAVV TVK SY+
Sbjct: 768 YLEQIKFYSHQLKICSQVKAEIQNLGGELIMSALDSVTSLIQAAKNLMNAVVQTVKMSYI 827
Query: 838 ASTKYQKVYGTAAVNSPVVSWKMKAPEKKPLVKREKPEEFQTRVRRGSQKKHISPVQALS 897
ASTK ++ A PVV W+MKAP KKPL+KREKPEE VRRGS KK I P+Q +S
Sbjct: 828 ASTKIIRIQSPAGPRHPVVMWRMKAPAKKPLIKREKPEETCAAVRRGSAKKKIHPLQVMS 887
Query: 898 EFK 900
EF+
Sbjct: 888 EFR 890
>gi|4503129 catenin, alpha-like 1 [Homo sapiens]
Length = 734
Score = 201 bits (512), Expect = 2e-51
Identities = 150/506 (29%), Positives = 252/506 (49%), Gaps = 26/506 (5%)
Query: 17 LEIRTLTVERLLEPLVTQVTTLVNTSNKGPSGKKKGRSKKA-HVLAASVEQATQNFLEKG 75
LEI+T +VE+ L PLV+Q+TTL+N + + KK ++ +A + +V A F++ G
Sbjct: 30 LEIKTRSVEQTLLPLVSQITTLINHKD---NTKKSDKTLQAIQRVGQAVNLAVGRFVKVG 86
Query: 76 EQIAKESQDLKEELVAAVEDVRKQGETMRIASS-------EFADDPCSSVKRGTMVRAAR 128
E IA E+ DLKEE+ A + ++ GET+ + E + +++AAR
Sbjct: 87 EAIANENWDLKEEINIACIEAKQAGETIAALTDITNLNHLESDGQITIFTDKTGVIKAAR 146
Query: 129 ALLSAVTRLLILADMADVMRLLSHLKIVEEALEAVKNATNEQDLANRFKEFGKEMVKLNY 188
LLS+VT++L+LAD + ++++ V +E ++ + Q+ F +FG EMV+ +
Sbjct: 147 LLLSSVTKVLLLADRVVIKQIITSRNKVLATMERLEKVNSFQEFVQIFSQFGNEMVEFAH 206
Query: 189 VAARRQQELKDPHCRDEMAAARGALKKNATMLYTASQAFLRHPDVAATRANRDYVFKQVQ 248
++ RQ +LKD + +MAAAR L+K ML TAS+ LRHP+ + N++ VF +++
Sbjct: 207 LSGDRQNDLKDEKKKAKMAAARAVLEKCTMMLLTASKTCLRHPNCESAHKNKEGVFDRMK 266
Query: 249 EAIAGISNAAQATSPTDEAKGHTGIGELA--AALNEFDNKI--ILDPMTFSEARFRPSLE 304
A+ + P G T I ++ + EF I + + + F + +L
Sbjct: 267 VALDKVIEIVTDCKP----NGETDISSISIFTGIKEFKMNIEALRENLYFQS---KENLS 319
Query: 305 ERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMNNTGRKEK--GDPL 362
LE I+ DS+ T + RERI+ R LQ L+S ++ +K K + L
Sbjct: 320 VTLEVILERMEDFTDSAYTSHEHRERILELSTQARMELQQLISVWIQAQSKKTKSIAEEL 379
Query: 363 NIAIDKMTKKTRDLRRQLRKAVMDHISD--SFLETNVPLLVLIEAAKSGNEKEVKEYAQV 420
++I K++ +L+++L +D + +V L L GN + + EYA
Sbjct: 380 ELSILKISHSLNELKKELHSTATQLAADLLKYHADHVVLKALKLTGVEGNLEALAEYACK 439
Query: 421 FREHANKLVEVANLACSISNNEEGVKLVRMAATQIDSLCPQVINAALTLAARPQSKVAQD 480
E +LVE L IS E A Q+I+AA TL P SK+A++
Sbjct: 440 LSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETLTLHPSSKIAKE 499
Query: 481 NMDVFKDQWEKQVRVLTEAVDDITSV 506
N+DVF + WE Q+ ++ + +I V
Sbjct: 500 NLDVFCEAWESQISDMSTLLREINDV 525
Score = 65.1 bits (157), Expect = 3e-10
Identities = 38/121 (31%), Positives = 61/121 (50%), Gaps = 1/121 (0%)
Query: 678 EEKAKIAEQVEIFHQEKSKLDAEVAKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGPLKN 737
EE+AKIA+ S D E+ KW+D N+I+ + M + + FTRG+GPLK
Sbjct: 560 EEQAKIAKLGLKLGLLTSDADCEIEKWEDQENEIVQYGRNMSSMAYSLYLFTRGEGPLKT 619
Query: 738 TSDVINAAKKIAEAGSRMDKLARAVADQCPDSACKQDLLAYLQRIALYCHQLNICSKVKA 797
+ D+I+ + A G ++ +A + Q D K LL + ++ CHQL +K
Sbjct: 620 SQDLIHQLEVFAAEGLKLTSSVQAFSKQLKDDD-KLMLLLEINKLIPLCHQLQTVTKTSL 678
Query: 798 E 798
+
Sbjct: 679 Q 679
>gi|4507877 vinculin isoform VCL [Homo sapiens]
Length = 1066
Score = 191 bits (486), Expect = 2e-48
Identities = 188/702 (26%), Positives = 306/702 (43%), Gaps = 60/702 (8%)
Query: 180 GKEMVKLNYVAARRQQEL-KDPHCRDEMAAARGALKKNATMLYTASQAFLRHPDVAATRA 238
G+E ++ AR+ EL DP RD++ + G + T+ A LR +
Sbjct: 404 GEEQIRGALAEARKIAELCDDPKERDDILRSLGEISA-----LTSKLADLRRQGKGDSPE 458
Query: 239 NRDYVFKQVQEAIAGI---SNAAQATSPTDEAKGHTGIGELAAALNEFDNKIILDPMTFS 295
R KQV A+ + +N A A S +A H G++ A DN + D
Sbjct: 459 ARALA-KQVATALQNLQTKTNRAVANSRPAKAAVHLE-GKIEQAQRWIDNPTV-DDRGVG 515
Query: 296 EARFRPSLEE--RLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMNNT 353
+A R + E RL +++ G R+ ++A+C+ V Q L
Sbjct: 516 QAAIRGLVAEGHRLANVMMGPY------------RQDLLAKCDRVDQLTAQLADLAARGE 563
Query: 354 GRKEKGDPLNIAIDKMTKKTRDLRRQLRKAVMDHISDSFLETNVPLLVLIEAAKSG---- 409
G + L ++ +DL+ ++++A+ +SD F +T P+ +L AA +
Sbjct: 564 GESPQARAL---ASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAP 620
Query: 410 NEKEV-KEYAQVFREHANKLVEVANLACSISN-NEEGVKLVRMAATQIDSLCPQVINAAL 467
N +EV E A F H+ KL A A ++ N+ V+ ++ + L PQV++AA
Sbjct: 621 NREEVFDERAANFENHSGKLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAAR 680
Query: 468 TLAARPQSKVAQDNMDVFKDQWEKQVRVLTEAVDDITSVDDFLSVSENHILEDVNKCVIA 527
L P ++ A ++ + K+QW V +T VD+ L SE I +D++KC +A
Sbjct: 681 ILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVA 740
Query: 528 LQEGDVDTLDRTAGAIRGRAARVIHIINAEMENYEAGVYTEKVLEATKLLSETVMPRFAE 587
+ L A +I RA R++ + E+EN E + E V A+ LS+T+ P +
Sbjct: 741 MANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVMD 800
Query: 588 QVEVAIEALSANVPQPFEENEFIDASRLVYDGVRDIRKAVLMIRTPEELEDDSDFEQEDY 647
+A++ N+ P + F+D+ + V +R+A + P+ D EQ
Sbjct: 801 -----AKAVAGNISDPGLQKSFLDSGYRILGAVAKVREA-FQPQEPDFPPPPPDLEQ--- 851
Query: 648 DVRSRTSVQTEDDQLIAGQSARAIMAQLPQEEKAKIAEQV--EIFHQ----EKSKLDAEV 701
+R + L G+ P+E+ + EQ E+ +Q +L E
Sbjct: 852 -LRLTDELAPPKPPLPEGE-VPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEA 909
Query: 702 AKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGPLKNTSDVINAAKKIAEAGSRMDKLARA 761
KW GNDII AK+M ++M EM+ RG K +I AK IA+A + +LA+
Sbjct: 910 RKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRA--LIQCAKDIAKASDEVTRLAKE 967
Query: 762 VADQCPDSACKQDLLAYLQRIALYCHQLNICSKVKAEVQNLGGELIVSGLDSATSLIQAA 821
VA QC D + +LL +RI QL I S VKA + + L+ A
Sbjct: 968 VAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNA 1027
Query: 822 KNLMNAVVLTVKASYVASTKYQKVYGTAAVNSPVVSWKMKAP 863
+NLM +V TV+ + AS K + G + W K P
Sbjct: 1028 QNLMQSVKETVREAEAASIKIRTDAGF------TLRWVRKTP 1063
Score = 85.9 bits (211), Expect = 2e-16
Identities = 87/377 (23%), Positives = 159/377 (42%), Gaps = 25/377 (6%)
Query: 21 TLTVERLLEPLVTQVTTLVNTSNKGPSGKKKGRSKKAHVLAASVEQATQNFLEKGEQIAK 80
T T+E +LEP+ Q++ LV +G K A V A+V+ A N + G++ +
Sbjct: 6 TRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPV--AAVQAAVSNLVRVGKETVQ 63
Query: 81 ESQD--LKEELVAAVEDVRKQGETMRIASSEFADDPCSSVKRGTMVRAARALLSAVTRLL 138
++D LK ++ A V + A+ DP S R ++ +R +LS + LL
Sbjct: 64 TTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLL 123
Query: 139 ILADMADVMRLLSHLKIVEEALEAVKNATNEQDLANRFKEFGKEMVKLNYVAARRQQELK 198
+ D A+V +++ K + E L + +DL K G M K+ + RQQEL
Sbjct: 124 LTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELT 183
Query: 199 DPHCRDEMAAARGALKKNATMLYTASQAFL-----RHPDVAATRANRDYVFKQVQEAIAG 253
R + + +K+ +L +A + F+ ++ + NR++ +++ I
Sbjct: 184 HQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINE 243
Query: 254 ISNAAQATSPTDEAKGHTGIGELAAALNEFDNKI------ILDPMTFSEARFRPSLEERL 307
I Q TS ++A + AL D+K+ + DP A + E+ +
Sbjct: 244 IIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDP----SASPGDAGEQAI 299
Query: 308 ESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMNNTGRK----EKGDPLN 363
I+ A + + C +RRE I+ C + Q + G +K ++
Sbjct: 300 RQILDEAGKVGE-LCAGKERRE-ILGTCKMLGQMTDQVADLRARGQGSSPVAMQKAQQVS 357
Query: 364 IAIDKMTKKTRDLRRQL 380
+D +T K + R+L
Sbjct: 358 QGLDVLTAKVENAARKL 374
>gi|7669550 vinculin isoform meta-VCL [Homo sapiens]
Length = 1134
Score = 135 bits (341), Expect = 1e-31
Identities = 176/763 (23%), Positives = 299/763 (39%), Gaps = 114/763 (14%)
Query: 180 GKEMVKLNYVAARRQQEL-KDPHCRDEMAAARGALKKNATMLYTASQAFLRHPDVAATRA 238
G+E ++ AR+ EL DP RD++ + G + T+ A LR +
Sbjct: 404 GEEQIRGALAEARKIAELCDDPKERDDILRSLGEISA-----LTSKLADLRRQGKGDSPE 458
Query: 239 NRDYVFKQVQEAIAGI---SNAAQATSPTDEAKGHTGIGELAAALNEFDNKIILDPMTFS 295
R KQV A+ + +N A A S +A H G++ A DN + D
Sbjct: 459 ARALA-KQVATALQNLQTKTNRAVANSRPAKAAVHLE-GKIEQAQRWIDNPTV-DDRGVG 515
Query: 296 EARFRPSLEE--RLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMNNT 353
+A R + E RL +++ G R+ ++A+C+ V Q L
Sbjct: 516 QAAIRGLVAEGHRLANVMMGPY------------RQDLLAKCDRVDQLTAQLADLAARGE 563
Query: 354 GRKEKGDPLNIAIDKMTKKTRDLRRQLRKAVMDHISDSFLETNVPLLVLIEAAKSG---- 409
G + L ++ +DL+ ++++A+ +SD F +T P+ +L AA +
Sbjct: 564 GESPQARAL---ASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAP 620
Query: 410 NEKEV-KEYAQVFREHANKLVEVANLACSISN-NEEGVKLVRMAATQIDSLCPQVINAAL 467
N +EV E A F H+ KL A A ++ N+ V+ ++ + L PQV++AA
Sbjct: 621 NREEVFDERAANFENHSGKLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAAR 680
Query: 468 TLAARPQSKVAQDNMDVFKDQWEKQVRVLTEAVDDITSVDDFLSVSENHILEDVNKCVIA 527
L P ++ A ++ + K+QW V +T VD+ L SE I +D++KC +A
Sbjct: 681 ILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVA 740
Query: 528 LQEGDVDTLDRTAGAIRGRAARVIHIINAEMENYEAGVYTEKVLEATKLLSETVMPRFAE 587
+ L A +I RA R++ + E+EN E + E V A+ LS+T+ P +
Sbjct: 741 MANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVMD 800
Query: 588 QVEVAIEALSANVPQPFEENEFIDASRLVYDGVRDIRKA--------------VLMIRTP 633
+A++ N+ P + F+D+ + V +R+A + +R
Sbjct: 801 -----AKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEPDFPPPPPDLEQLRLT 855
Query: 634 EELEDDSDFEQEDYDVRSRTSVQTEDDQLIAGQSARAIMAQLPQEEKAKIAEQVEIFHQE 693
+EL E R E D+ Q A ++ Q ++ ++ + +
Sbjct: 856 DELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSK 915
Query: 694 KSKLDAEVA--------------------KWDDSGNDIIVL-----AKQMCMIMMEMTDF 728
AEV DD +++++ Q + +
Sbjct: 916 PGIPAAEVGIGVVAEADAADAAGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHR 975
Query: 729 TRGKGPLKNTSDVINAAKKIAEAGSRMDKLARA--------------------------- 761
K K +D+I AAK++A + M +L R
Sbjct: 976 EATKWSSKG-NDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAK 1034
Query: 762 -VADQCPDSACKQDLLAYLQRIALYCHQLNICSKVKAEVQNLGGELIVSGLDSATSLIQA 820
VA QC D + +LL +RI QL I S VKA + + L+
Sbjct: 1035 EVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHN 1094
Query: 821 AKNLMNAVVLTVKASYVASTKYQKVYGTAAVNSPVVSWKMKAP 863
A+NLM +V TV+ + AS K + G + W K P
Sbjct: 1095 AQNLMQSVKETVREAEAASIKIRTDAGF------TLRWVRKTP 1131
Score = 85.9 bits (211), Expect = 2e-16
Identities = 87/377 (23%), Positives = 159/377 (42%), Gaps = 25/377 (6%)
Query: 21 TLTVERLLEPLVTQVTTLVNTSNKGPSGKKKGRSKKAHVLAASVEQATQNFLEKGEQIAK 80
T T+E +LEP+ Q++ LV +G K A V A+V+ A N + G++ +
Sbjct: 6 TRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPV--AAVQAAVSNLVRVGKETVQ 63
Query: 81 ESQD--LKEELVAAVEDVRKQGETMRIASSEFADDPCSSVKRGTMVRAARALLSAVTRLL 138
++D LK ++ A V + A+ DP S R ++ +R +LS + LL
Sbjct: 64 TTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLL 123
Query: 139 ILADMADVMRLLSHLKIVEEALEAVKNATNEQDLANRFKEFGKEMVKLNYVAARRQQELK 198
+ D A+V +++ K + E L + +DL K G M K+ + RQQEL
Sbjct: 124 LTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELT 183
Query: 199 DPHCRDEMAAARGALKKNATMLYTASQAFL-----RHPDVAATRANRDYVFKQVQEAIAG 253
R + + +K+ +L +A + F+ ++ + NR++ +++ I
Sbjct: 184 HQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINE 243
Query: 254 ISNAAQATSPTDEAKGHTGIGELAAALNEFDNKI------ILDPMTFSEARFRPSLEERL 307
I Q TS ++A + AL D+K+ + DP A + E+ +
Sbjct: 244 IIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDP----SASPGDAGEQAI 299
Query: 308 ESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMNNTGRK----EKGDPLN 363
I+ A + + C +RRE I+ C + Q + G +K ++
Sbjct: 300 RQILDEAGKVGE-LCAGKERRE-ILGTCKMLGQMTDQVADLRARGQGSSPVAMQKAQQVS 357
Query: 364 IAIDKMTKKTRDLRRQL 380
+D +T K + R+L
Sbjct: 358 QGLDVLTAKVENAARKL 374
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 47.0 bits (110), Expect = 8e-05
Identities = 129/688 (18%), Positives = 261/688 (37%), Gaps = 73/688 (10%)
Query: 60 LAASVEQATQNFLEK---GEQIAKESQDLKEELVAAVEDV-------RKQGETMRIASSE 109
L A++ +A Q EK +++A + L+E++ A ++V RK GE AS E
Sbjct: 877 LHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRE 936
Query: 110 FADDPCSSVKR---------GTMVRAARALLSAVTRLLILADMADVMRLLSHLKIVEEAL 160
+P + R G + +A L A+ R M + + L + +
Sbjct: 937 LVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREA--EQMGNELERLRAALMESQGQ 994
Query: 161 EAVKNATNEQDLANRFKEFGKEMVKLNYV-AARRQQELKDPHCRDEMAAARGALKKNATM 219
+ + E+++A +E G+ L AAR + E++ + +E L++
Sbjct: 995 QQEERGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAH 1054
Query: 220 LYTASQAFLRHPDVAATRANRDYVFKQVQEAIAGISNAAQ--ATSPTDEAKGHTGIGELA 277
T + + ++A R K+++E + + A + A G E A
Sbjct: 1055 ALTEKEG--KDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAA 1112
Query: 278 AALNEFDNKIILDPMTFSEARFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNA 337
K L+ + ++ +++ E S + +R +R +
Sbjct: 1113 GRTEPTGPK--LEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQ 1170
Query: 338 VRQALQDLLSEYMNNTGRKEKGDPLNIAIDKMTKKTRDLRRQL----RKAVMDHISDSFL 393
+ + Q+L + + + +K + + Q+ ++A + S L
Sbjct: 1171 LEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSL 1230
Query: 394 ETNVPLLVLIEAAKSGNEKEVKEYAQVFREHANKLVEVANL--ACSISNNEEGVKLVRMA 451
E V +L K G KE+K E + KL E L A + SN+ +
Sbjct: 1231 EEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSAL 1290
Query: 452 ATQIDSL---------CPQVINAALTLAARPQSKVAQDNMDVFKDQWEKQVRVLTEAVDD 502
++ SL + + LT A ++ Q+ + +++++ ++ + L+ +
Sbjct: 1291 REEVQSLREEAEKQRVASENLRQELTSQAERAEELGQE-LKAWQEKFFQKEQALSTLQLE 1349
Query: 503 ITSVDDFLS--VSENHILEDVNKCVIALQEGDVDTLDRTAGAIRGRAARVIHIINAEMEN 560
TS +S + H+ + + A ++ + L+++ A G A ++ A+ E
Sbjct: 1350 HTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRA---ELLRAQREL 1406
Query: 561 YEAGVYTEKVLEATKLLSETVMPR--FAEQVEVAIEALSANVPQPFEENEFIDASRLVYD 618
E +KV E + + + +AEQ+ + +A EEN
Sbjct: 1407 GELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLA----EEN----------- 1451
Query: 619 GVRDIRKAVLMIRTPEELEDD---SDFEQEDYDVRSRTSVQTEDDQLIAGQSARAIMAQL 675
R + + + R E+E D + QE VR+ + + Q A +AR +
Sbjct: 1452 --RGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMT 1509
Query: 676 PQEE--KAKIAEQVEIFHQEKSKLDAEV 701
+ E K K+ E+ + F +E+ KL A+V
Sbjct: 1510 AKYEGAKVKVLEERQRFQEERQKLTAQV 1537
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 45.1 bits (105), Expect = 3e-04
Identities = 99/518 (19%), Positives = 206/518 (39%), Gaps = 52/518 (10%)
Query: 273 IGELAAALNEFDNKIILD-----PMTFSEARFRPSLEERLESIISGAALMADS-SCTRDD 326
IG L N F NKI + M + R +E + + ++ D+ S T +
Sbjct: 380 IGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQ 439
Query: 327 RRERIVAECNAVRQALQDLLSEYMNNTGR-----------KEKGDPLNIAIDKMTKKTRD 375
+ AE N +RQ L++E TG+ ++ L + + + ++ +
Sbjct: 440 LESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEE 499
Query: 376 LRRQLRKAVMDHISDSFLETNVPLLVLIEAAKSGNEKEVKEYAQVFREHANKLVEVANLA 435
++ +RK +H ++ + V E ++ + ++ +L+++
Sbjct: 500 VQSYIRKRTAEH--EAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESE 557
Query: 436 CSISNNEEGVKL-VRMAATQIDSLCPQVINAALTLAARPQSKVAQDNMDVFKDQWEKQVR 494
N EE +++ V+ Q ++L Q+ +AA+ + V + + + +KQ++
Sbjct: 558 QKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIK 617
Query: 495 VLTEAVDDITSVDDFLSVSENHILEDVNKCVIALQEGDVDTLDRTAGAIRGRAARVIHII 554
+ D + S D L+ E L+D+ L + +V L A+ A H
Sbjct: 618 ---QTEDSLASERDRLTSKEEE-LKDIQNMNFLL-KAEVQKLQ----ALANEQAAAAH-- 666
Query: 555 NAEMENYEAGVYTEKVLEATKLLSETVMPRFAEQVE--VAIEALSANVPQPFEENEFIDA 612
E+E + VY + + +LL E + + ++E + + + ++ + + +
Sbjct: 667 --ELEKMQQSVYVKD--DKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVS 722
Query: 613 SRLVYDGVRDIRKAVL----MIRTPEELEDD-----SDFEQEDYDVRSRTSVQTEDDQ-L 662
+ D V + K + ++T EEL + + E+E +R+ S T++ Q L
Sbjct: 723 EQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDL 782
Query: 663 IAGQSARAIMAQLPQEEKAKIAEQVEIFHQEKSKLDAEVAKWDDSGNDIIVLAKQMCMIM 722
A Q+ + A L +E K I E+ + L+AE+ K N + + +
Sbjct: 783 KAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLK---VANKEKTVQLSITSKV 839
Query: 723 MEMTDFTRGKGPLKNTSDVI--NAAKKIAEAGSRMDKL 758
E+ + +GK NT + K +A G + L
Sbjct: 840 QELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDL 877
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 44.3 bits (103), Expect = 5e-04
Identities = 105/536 (19%), Positives = 205/536 (38%), Gaps = 99/536 (18%)
Query: 273 IGELAAALNEFDNKIILDPMTFSEARFRPSLEERLESIISGAALMADSSCTRDDRRERIV 332
IGE+ LN+ D ++ L+E L+S ++ A S + D R+R++
Sbjct: 2159 IGEIQVTLNKKDKEV-------------QQLQENLDSTVTQLAAFTKSMSSLQDDRDRVI 2205
Query: 333 AECNAVRQALQDLLSEYMNNTGRKEKG-DPLNIAIDKMTKKTRDLRRQLRKAVMD-HISD 390
E + D + KE L + +M+ +L+ + + D I +
Sbjct: 2206 DEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWE 2265
Query: 391 SFLETNVPLLVLIEAAKSGNEKEVKEYAQVFREHANKLVEVANLACSISNNEEGVKLVRM 450
S +T V L + G KE+ ++L E +L S N E KL
Sbjct: 2266 SKAQTEVQLQQKVCDTLQGENKEL----------LSQLEETRHLYHSSQN--ELAKL--- 2310
Query: 451 AATQIDSLCPQVINAALTLAARPQSK------VAQDNMDVFKDQWE-KQVRVLTEAVDDI 503
+++ SL Q+ + + +L + K + Q D+ ++ +Q+ +A ++
Sbjct: 2311 -ESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASREL 2369
Query: 504 TSVDDFLSVSENHILEDVN---KCVIALQEGDVDTLDRTAGAIRGRAARVIH-----IIN 555
TS + E++N + +I+L G + + +R + + I +
Sbjct: 2370 TS----------RLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQ 2419
Query: 556 AEMENYEAGVYTEKVLEATKLLSETVMPRFAEQVEVAIEALSANVPQPFEENEFIDASRL 615
E EN +K ++ T L ET+ E N+ Q + + F+
Sbjct: 2420 EEEENIVLEEENKKAVDKTNQLMETLKTIKKE-----------NIQQKAQLDSFV----- 2463
Query: 616 VYDGVRDIRKAVLMIRTPEELEDDSDFEQEDYDV--RSRTSVQTEDDQLIAGQSARAIMA 673
++ L++D D DY S+ E DQLI Q A A
Sbjct: 2464 ---------------KSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLI--QEAAAENN 2506
Query: 674 QLPQEEKAKIAEQVEIFHQEKSKLDAEVAKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKG 733
+L +E + + ++ + E +KLDAE+ ++ + N +I + ++E+ + K
Sbjct: 2507 KLKEEIRG-LRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEV-QLQQNKE 2564
Query: 734 PLKNTSDVINAAKKIAEAGSRMDKLARAVADQCPDSACKQDLLAYLQRIALYCHQL 789
+ + K+ EA + + A+ ++ KQDL ++ + + QL
Sbjct: 2565 LENKYAKLEEKLKESEEANEDLRRSFNALQEE------KQDLSKEIESLKVSISQL 2614
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 43.9 bits (102), Expect = 7e-04
Identities = 103/538 (19%), Positives = 217/538 (40%), Gaps = 69/538 (12%)
Query: 273 IGELAAALNEFDNKIILD-----PMTFSEARFRPSLEERLESIISGAALMADS-SCTRDD 326
IG L N F NKI + M + R +E + + ++ D+ S T +
Sbjct: 380 IGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQ 439
Query: 327 RRERIVAECNAVRQALQDLLSEYMNNTGR-----------KEKGDPLNIAIDKMTKKTRD 375
+ AE N +RQ L++E TG+ ++ L + + + ++ +
Sbjct: 440 LESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEE 499
Query: 376 LRRQLRKAVMDHISDSFLETNVPLLVLIEAAKSGNEKEVKEYAQVFREHANKLVEVANLA 435
++ +RK +H ++ + V E ++ + ++ +L+++
Sbjct: 500 VQSYIRKRTAEH--EAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESE 557
Query: 436 CSISNNEEGVKL-VRMAATQIDSLCPQVINAALTLAARPQSKVAQDNMDVFKDQWEKQVR 494
N EE +++ V+ Q ++L Q+ +AA+ + V + + + +KQ++
Sbjct: 558 QKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIK 617
Query: 495 VLTEAVDDITSVDDFLSVSENHILEDVNKCVIALQEGDVDTLDRTAGAIRGRAARVIHII 554
+ D + S D L+ E L+D+ L + +V L A+ A H
Sbjct: 618 ---QTEDSLASERDRLTSKEEE-LKDIQNMNFLL-KAEVQKLQ----ALANEQAAAAH-- 666
Query: 555 NAEMENYEAGVYTEKVLEATKLLSETVMPRFAEQVE--VAIEALSANVPQPFEENEFIDA 612
E+E + VY + + +LL E + + ++E + + + ++ + + +
Sbjct: 667 --ELEKMQQSVYVKD--DKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVS 722
Query: 613 SRLVYDGVRDIRKAVL----MIRTPEELEDD-----SDFEQEDYDVRSRTSVQTEDDQ-L 662
+ D V + K + ++T EEL + + E+E +R+ S T++ Q L
Sbjct: 723 EQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDL 782
Query: 663 IAGQSARAIMAQLPQEEKAKI---------------AEQVEIFHQEKSKLDAE---VAKW 704
A Q+ + A L +E K I AE +++ ++EK+ D + A
Sbjct: 783 KAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALK 842
Query: 705 DDSGNDIIVLAKQMCMI--MMEMTDFTRGKGPLKNTSDVI--NAAKKIAEAGSRMDKL 758
++ GN + A+Q+ + + E+ + +GK NT + K +A G + L
Sbjct: 843 EEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDL 900
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 43.9 bits (102), Expect = 7e-04
Identities = 103/538 (19%), Positives = 217/538 (40%), Gaps = 69/538 (12%)
Query: 273 IGELAAALNEFDNKIILD-----PMTFSEARFRPSLEERLESIISGAALMADS-SCTRDD 326
IG L N F NKI + M + R +E + + ++ D+ S T +
Sbjct: 380 IGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQ 439
Query: 327 RRERIVAECNAVRQALQDLLSEYMNNTGR-----------KEKGDPLNIAIDKMTKKTRD 375
+ AE N +RQ L++E TG+ ++ L + + + ++ +
Sbjct: 440 LESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEE 499
Query: 376 LRRQLRKAVMDHISDSFLETNVPLLVLIEAAKSGNEKEVKEYAQVFREHANKLVEVANLA 435
++ +RK +H ++ + V E ++ + ++ +L+++
Sbjct: 500 VQSYIRKRTAEH--EAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESE 557
Query: 436 CSISNNEEGVKL-VRMAATQIDSLCPQVINAALTLAARPQSKVAQDNMDVFKDQWEKQVR 494
N EE +++ V+ Q ++L Q+ +AA+ + V + + + +KQ++
Sbjct: 558 QKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIK 617
Query: 495 VLTEAVDDITSVDDFLSVSENHILEDVNKCVIALQEGDVDTLDRTAGAIRGRAARVIHII 554
+ D + S D L+ E L+D+ L + +V L A+ A H
Sbjct: 618 ---QTEDSLASERDRLTSKEEE-LKDIQNMNFLL-KAEVQKLQ----ALANEQAAAAH-- 666
Query: 555 NAEMENYEAGVYTEKVLEATKLLSETVMPRFAEQVE--VAIEALSANVPQPFEENEFIDA 612
E+E + VY + + +LL E + + ++E + + + ++ + + +
Sbjct: 667 --ELEKMQQSVYVKD--DKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVS 722
Query: 613 SRLVYDGVRDIRKAVL----MIRTPEELEDD-----SDFEQEDYDVRSRTSVQTEDDQ-L 662
+ D V + K + ++T EEL + + E+E +R+ S T++ Q L
Sbjct: 723 EQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDL 782
Query: 663 IAGQSARAIMAQLPQEEKAKI---------------AEQVEIFHQEKSKLDAE---VAKW 704
A Q+ + A L +E K I AE +++ ++EK+ D + A
Sbjct: 783 KAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALK 842
Query: 705 DDSGNDIIVLAKQMCMI--MMEMTDFTRGKGPLKNTSDVI--NAAKKIAEAGSRMDKL 758
++ GN + A+Q+ + + E+ + +GK NT + K +A G + L
Sbjct: 843 EEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDL 900
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 43.9 bits (102), Expect = 7e-04
Identities = 103/538 (19%), Positives = 217/538 (40%), Gaps = 69/538 (12%)
Query: 273 IGELAAALNEFDNKIILD-----PMTFSEARFRPSLEERLESIISGAALMADS-SCTRDD 326
IG L N F NKI + M + R +E + + ++ D+ S T +
Sbjct: 380 IGTLEKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQ 439
Query: 327 RRERIVAECNAVRQALQDLLSEYMNNTGR-----------KEKGDPLNIAIDKMTKKTRD 375
+ AE N +RQ L++E TG+ ++ L + + + ++ +
Sbjct: 440 LESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEAERRWEE 499
Query: 376 LRRQLRKAVMDHISDSFLETNVPLLVLIEAAKSGNEKEVKEYAQVFREHANKLVEVANLA 435
++ +RK +H ++ + V E ++ + ++ +L+++
Sbjct: 500 VQSYIRKRTAEH--EAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESE 557
Query: 436 CSISNNEEGVKL-VRMAATQIDSLCPQVINAALTLAARPQSKVAQDNMDVFKDQWEKQVR 494
N EE +++ V+ Q ++L Q+ +AA+ + V + + + +KQ++
Sbjct: 558 QKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIK 617
Query: 495 VLTEAVDDITSVDDFLSVSENHILEDVNKCVIALQEGDVDTLDRTAGAIRGRAARVIHII 554
+ D + S D L+ E L+D+ L + +V L A+ A H
Sbjct: 618 ---QTEDSLASERDRLTSKEEE-LKDIQNMNFLL-KAEVQKLQ----ALANEQAAAAH-- 666
Query: 555 NAEMENYEAGVYTEKVLEATKLLSETVMPRFAEQVE--VAIEALSANVPQPFEENEFIDA 612
E+E + VY + + +LL E + + ++E + + + ++ + + +
Sbjct: 667 --ELEKMQQSVYVKD--DKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVS 722
Query: 613 SRLVYDGVRDIRKAVL----MIRTPEELEDD-----SDFEQEDYDVRSRTSVQTEDDQ-L 662
+ D V + K + ++T EEL + + E+E +R+ S T++ Q L
Sbjct: 723 EQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDL 782
Query: 663 IAGQSARAIMAQLPQEEKAKI---------------AEQVEIFHQEKSKLDAE---VAKW 704
A Q+ + A L +E K I AE +++ ++EK+ D + A
Sbjct: 783 KAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALK 842
Query: 705 DDSGNDIIVLAKQMCMI--MMEMTDFTRGKGPLKNTSDVI--NAAKKIAEAGSRMDKL 758
++ GN + A+Q+ + + E+ + +GK NT + K +A G + L
Sbjct: 843 EEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDL 900
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 43.5 bits (101), Expect = 9e-04
Identities = 119/650 (18%), Positives = 245/650 (37%), Gaps = 86/650 (13%)
Query: 54 SKKAHVLAASVEQATQNFLEKGEQIAKESQDLKEELVAAVEDVRKQGETMR-IASSEFAD 112
S++ L + Q TQ + E+ + Q L ++ ++D K+ E ++ + E D
Sbjct: 1441 SQRKQQLEVELRQVTQM---RTEESVRYKQSL-DDAAKTIQDKNKEIERLKQLIDKETND 1496
Query: 113 DPCSSVKRGTMVRAARALLSAVTRLLILADMADVMRL-LSHLKIVEEALEAVKNATNEQD 171
C + + R L A + + V L+ L+I E + + +QD
Sbjct: 1497 RKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQ-ERTVKDQD 1555
Query: 172 LA---NRFKEFGKEMVKLNYVAARRQQELKDPHCR-----DEMAAARGALKKNATMLYTA 223
+ N KE + K+ R ++ + C+ +E+ R +LK+ A +
Sbjct: 1556 ITRFQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNL 1615
Query: 224 SQAFLRHPDVAATRANRDYVFKQVQEAIAGISNAAQATSPTDEAKGHTGIGELAAALNEF 283
+Q L + R+ D +Q ++ + G Q T + L++ +
Sbjct: 1616 TQQ-LEQASIVKKRSEDD--LRQQRDVLDGHLREKQRTQEE--------LRRLSSEVEAL 1664
Query: 284 DNKIILDPMTFSEARFRPSLEERLESIISGAALMADSSCTRDDR----RERIVAECNAVR 339
+++ + + +A R E + I + + S +R E + E +
Sbjct: 1665 RRQLLQEQESVKQAHLR---NEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLE 1721
Query: 340 QALQDLLSEYMN-NTGRKEKGDPLNIAIDKMTKKTRDLRRQLRKAVMDHISDSFLETNVP 398
+ L++L EY + GR E N I +LR QL+ IS++
Sbjct: 1722 EELRNLRLEYDDLRRGRSEADSDKNATI-------LELRSQLQ------ISNNRTLELQG 1768
Query: 399 LLVLIEAAKSGNEKEVKEYAQVFREHANKLVEVANLACSISNNEEG----VKLVRMAATQ 454
L+ ++ + +E++++ + E +N++ E N + E +K++ +
Sbjct: 1769 LINDLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKAR 1828
Query: 455 IDSLCPQVINAALTLAA--RPQSKVAQDNMDVFKD--QWEKQVRVLTEAVDDITSVDDFL 510
+ L ++ A TL A R + ++ + + D QW+ Q EA+ I S +
Sbjct: 1829 LQRLEDELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKS 1888
Query: 511 SVSENHILEDVNKCVIALQEGDVDTLDRTAGAIRGRAARVIHIINAEMENYEAGVYTEKV 570
+N + +++ L I R R + E
Sbjct: 1889 EREKNSL------------RSEIERLQAEIKRIEERCRRKL----------------EDS 1920
Query: 571 LEATKLLSETVMPRFAEQVEVAIEALSANVPQPFEENEF-IDASRLVYDGVRDIRKAVLM 629
T+ ET R+ +++ + + + E E+ +D S+LV+DG+R +K M
Sbjct: 1921 TRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVFDGLR--KKVTAM 1978
Query: 630 IRTPEELEDDSDFEQEDYDVRSRTSVQTEDDQLIAGQSARAIMAQLPQEE 679
+L D + ++ +S V +E + G + A + P+E+
Sbjct: 1979 QLYECQLIDKTTLDKLLKGKKSVEEVASEIQPFLRGAGSIAGASASPKEK 2028
Score = 30.4 bits (67), Expect = 7.8
Identities = 21/112 (18%), Positives = 55/112 (49%), Gaps = 6/112 (5%)
Query: 696 KLDAEVAKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGPLKNTSDVINAAKKIAEAGSRM 755
+++ ++ + +G+++ +Q+ + + ++T R + ++ + +AAK I + +
Sbjct: 1425 RVEEDIQQQKATGSEVSQRKQQLEVELRQVTQM-RTEESVRYKQSLDDAAKTIQDKNKEI 1483
Query: 756 DKLARAVADQCPDSACKQDLLAYLQRIALYCHQLN-----ICSKVKAEVQNL 802
++L + + + D C +D A LQR+ + N +K+K + Q L
Sbjct: 1484 ERLKQLIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQEL 1535
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 43.5 bits (101), Expect = 9e-04
Identities = 125/670 (18%), Positives = 265/670 (39%), Gaps = 76/670 (11%)
Query: 65 EQATQNFLEKGEQ-IAKESQDLKEELVAAVEDVRKQGETMRIASSEFADDPCSSVKRGTM 123
E+AT+ EK A+E ++L E L A Q E + +EF ++ T+
Sbjct: 1126 ERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLR-RDLEEATL 1184
Query: 124 VRAARALLSAVTRLLILADMADVMRLLSHLKIVEEALEAVKNATNEQ--DLANRFKEFGK 181
A + A R +A++ + +L+ V++ LE K+ + DL++ + K
Sbjct: 1185 QHEA---MVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSK 1241
Query: 182 EMVKLNYVAARRQQELKDPHCR-DEMAAARGALKKNATMLYTASQAFLRHPD-----VAA 235
L + + +L + + +E+ + L + L T + R + V+
Sbjct: 1242 SKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQ 1301
Query: 236 TRANRDYVFKQVQEAIAGISNAAQATSPTDEA----------------KGHTGIGELAAA 279
++ +Q +E + +A + A + G EL A
Sbjct: 1302 LSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRA 1361
Query: 280 LNEFDNKIILDPMTFSEARFRPSLE----ERLESIISGAALMADSSCTRDDRRERIVAEC 335
L++ ++++ A++R E +R E + +A +++ E + A+C
Sbjct: 1362 LSKANSEV---------AQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKC 1412
Query: 336 NAVRQALQDLLSEYMNNTGRKEKGDPLNIAIDKMTKKTRDLRRQLRKAVMDHISD--SFL 393
++ + Q L E + E+ + L A+DK + + + + + ++ + L
Sbjct: 1413 ASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASL 1472
Query: 394 ETNVPLLVLIEAAKSGNEKEVKEYAQVFREHANKLVEVANLACSISNNEEGVKLVRMAAT 453
+ + L + K+ E+ + + V RE+ N E+A+L I+ N + + + +
Sbjct: 1473 KESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRK 1532
Query: 454 QID------SLCPQVINAAL----TLAARPQSKVAQDNMDVFK------DQWEKQVRVLT 497
QI+ L + AAL R Q ++ Q ++ + ++ E+ R
Sbjct: 1533 QIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQ 1592
Query: 498 EAVDDITSVDDFLSVSENHILEDVNKCVIALQEGDVDTLD-RTAGAIRGRAARVIHIINA 556
V+ + S D S N + K EGD++ ++ + + A R A + H+ +
Sbjct: 1593 RTVETMQSALDAEVRSRNEAIRLKKK-----MEGDLNEIEIQLSHANRQAAETLKHLRSV 1647
Query: 557 EMENYEAGVYTEKVLEATKLLSE--TVMPRFAEQVEVAIEALSANVPQ-----PFEENEF 609
+ + + ++ + L + L E ++ R A ++ +E L A + Q E E
Sbjct: 1648 QGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQEL 1707
Query: 610 IDASRLVYDGVRDIRKAVLMIRTPEELEDDSDFEQEDYDVRSRTSVQTEDDQLIAGQSAR 669
+D++ V + +I T ++LE D Q + + SR + E+ A A
Sbjct: 1708 LDSNERVQ---LLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAA 1764
Query: 670 AIMAQLPQEE 679
+ +L +E+
Sbjct: 1765 MMAEELKKEQ 1774
>gi|169207319 PREDICTED: hypothetical protein [Homo sapiens]
Length = 828
Score = 41.2 bits (95), Expect = 0.004
Identities = 97/509 (19%), Positives = 198/509 (38%), Gaps = 73/509 (14%)
Query: 182 EMVKLNYVAARRQQELKDPHCRDEMAAARGALKKNATMLY---TASQAFLRHPDVAATRA 238
++ K N +Q+EL H R ++ + KK T +Y T ++ L+ D+A +
Sbjct: 155 DLTKYNEALGEKQEELARKHARFVLSLNQTMEKKATTTVYINETYTKINLKREDIALQK- 213
Query: 239 NRDYVFKQVQEAIAGISNAAQATSPTDEAKGHTGIGELAAALNEFDNKIILDPM-TFSEA 297
K +QE A+ + A+ EL A +NEF+N + M T+ +
Sbjct: 214 ------KCIQE--------AEELMEKERAEYLIRKQELTAQINEFENTREVKRMETYQKK 259
Query: 298 RFRPSLEERL----ESIISGAALMADSSCTRDDRRERI---VAECNAVRQALQDLLSEYM 350
+ L+ ++ E++ AA+++D + E I E + +++ L L ++
Sbjct: 260 KELDKLQTKMSKIKETVTVSAAVLSDHNLEIARLHESIRYWEQEVSELKKDLAILEAKLC 319
Query: 351 NNTGRKEKGDPL-NIAIDKMTKKTRDLRRQLRKAVMDHISDSFLETNVPLLVLIEAAKSG 409
T KEK D + N ++ K + L L A M++ E L + S
Sbjct: 320 FFTDNKEKLDDISNDEKNEFLNKIKQLVETLHAARMEY--KDLREKMKTLARQYKIVLSE 377
Query: 410 NEKEVKEYAQVFREHANKLVEVANLACSISNNEEGVKLVRMAATQIDSLCPQVINAALTL 469
EK + ++ E+ +L ++ +S +K + + Q + A
Sbjct: 378 EEKAFLQKQKIHDENQKQLTFISQKEYFLSQKRVDIKNMEEGLITL-----QELQQATKT 432
Query: 470 AARPQSKVAQDNMD-----VFKDQW------EKQVRVLTEAVDDITSVDDFLSVSENHIL 518
+ Q K+ N++ QW +K R + +I ++ + + +E +
Sbjct: 433 VYQQQIKILSANLERESQRCVITQWKMACLRKKHARWTAKIKAEIQAITEKIQNAEVRRI 492
Query: 519 EDVNKCVIALQE--GDVDTLDRTAGAIRGRAARVIH---IINAEMENYEAGVYTEKVLEA 573
E +N+ QE G V +++ ++ ++ ++ E+ YE E +
Sbjct: 493 ELLNETSFRQQEISGFVAQIEKLTTELKEEEKAFVNKEKMLMKELSKYEEIFVKETQINK 552
Query: 574 TKLLSETVMPRFAEQVEVA----------IEALSANVPQPFEENEFI---------DASR 614
K E + + Q++VA +E LS + +E + + D SR
Sbjct: 553 EK---EEELVEYLPQLQVAEQEYKEKRRKLEELSNIITAQRQEEDLLNNHIFLFTRDFSR 609
Query: 615 LVYDGVRDIRKAVLMIRTPEELEDDSDFE 643
+ + D+++ + +R E ++ FE
Sbjct: 610 YI-SNMEDVKQELQQLRDQESKKNKDHFE 637
>gi|169207756 PREDICTED: hypothetical protein [Homo sapiens]
Length = 828
Score = 41.2 bits (95), Expect = 0.004
Identities = 97/509 (19%), Positives = 198/509 (38%), Gaps = 73/509 (14%)
Query: 182 EMVKLNYVAARRQQELKDPHCRDEMAAARGALKKNATMLY---TASQAFLRHPDVAATRA 238
++ K N +Q+EL H R ++ + KK T +Y T ++ L+ D+A +
Sbjct: 155 DLTKYNEALGEKQEELARKHARFVLSLNQTMEKKATTTVYINETYTKINLKREDIALQK- 213
Query: 239 NRDYVFKQVQEAIAGISNAAQATSPTDEAKGHTGIGELAAALNEFDNKIILDPM-TFSEA 297
K +QE A+ + A+ EL A +NEF+N + M T+ +
Sbjct: 214 ------KCIQE--------AEELMEKERAEYLIRKQELTAQINEFENTREVKRMETYQKK 259
Query: 298 RFRPSLEERL----ESIISGAALMADSSCTRDDRRERI---VAECNAVRQALQDLLSEYM 350
+ L+ ++ E++ AA+++D + E I E + +++ L L ++
Sbjct: 260 KELDKLQTKMSKIKETVTVSAAVLSDHNLEIARLHESIRYWEQEVSELKKDLAILEAKLC 319
Query: 351 NNTGRKEKGDPL-NIAIDKMTKKTRDLRRQLRKAVMDHISDSFLETNVPLLVLIEAAKSG 409
T KEK D + N ++ K + L L A M++ E L + S
Sbjct: 320 FFTDNKEKLDDISNDEKNEFLNKIKQLVETLHAARMEY--KDLREKMKTLARQYKIVLSE 377
Query: 410 NEKEVKEYAQVFREHANKLVEVANLACSISNNEEGVKLVRMAATQIDSLCPQVINAALTL 469
EK + ++ E+ +L ++ +S +K + + Q + A
Sbjct: 378 EEKAFLQKQKIHDENQKQLTFISQKEYFLSQKRVDIKNMEEGLITL-----QELQQATKT 432
Query: 470 AARPQSKVAQDNMD-----VFKDQW------EKQVRVLTEAVDDITSVDDFLSVSENHIL 518
+ Q K+ N++ QW +K R + +I ++ + + +E +
Sbjct: 433 VYQQQIKILSANLERESQRCVITQWKMACLRKKHARWTAKIKAEIQAITEKIQNAEVRRI 492
Query: 519 EDVNKCVIALQE--GDVDTLDRTAGAIRGRAARVIH---IINAEMENYEAGVYTEKVLEA 573
E +N+ QE G V +++ ++ ++ ++ E+ YE E +
Sbjct: 493 ELLNETSFRQQEISGFVAQIEKLTTELKEEEKAFVNKEKMLMKELSKYEEIFVKETQINK 552
Query: 574 TKLLSETVMPRFAEQVEVA----------IEALSANVPQPFEENEFI---------DASR 614
K E + + Q++VA +E LS + +E + + D SR
Sbjct: 553 EK---EEELVEYLPQLQVAEQEYKEKRRKLEELSNIITAQRQEEDLLNNHIFLFTRDFSR 609
Query: 615 LVYDGVRDIRKAVLMIRTPEELEDDSDFE 643
+ + D+++ + +R E ++ FE
Sbjct: 610 YI-SNMEDVKQELQQLRDQESKKNKDHFE 637
>gi|169207046 PREDICTED: hypothetical protein [Homo sapiens]
Length = 828
Score = 41.2 bits (95), Expect = 0.004
Identities = 97/509 (19%), Positives = 198/509 (38%), Gaps = 73/509 (14%)
Query: 182 EMVKLNYVAARRQQELKDPHCRDEMAAARGALKKNATMLY---TASQAFLRHPDVAATRA 238
++ K N +Q+EL H R ++ + KK T +Y T ++ L+ D+A +
Sbjct: 155 DLTKYNEALGEKQEELARKHARFVLSLNQTMEKKATTTVYINETYTKINLKREDIALQK- 213
Query: 239 NRDYVFKQVQEAIAGISNAAQATSPTDEAKGHTGIGELAAALNEFDNKIILDPM-TFSEA 297
K +QE A+ + A+ EL A +NEF+N + M T+ +
Sbjct: 214 ------KCIQE--------AEELMEKERAEYLIRKQELTAQINEFENTREVKRMETYQKK 259
Query: 298 RFRPSLEERL----ESIISGAALMADSSCTRDDRRERI---VAECNAVRQALQDLLSEYM 350
+ L+ ++ E++ AA+++D + E I E + +++ L L ++
Sbjct: 260 KELDKLQTKMSKIKETVTVSAAVLSDHNLEIARLHESIRYWEQEVSELKKDLAILEAKLC 319
Query: 351 NNTGRKEKGDPL-NIAIDKMTKKTRDLRRQLRKAVMDHISDSFLETNVPLLVLIEAAKSG 409
T KEK D + N ++ K + L L A M++ E L + S
Sbjct: 320 FFTDNKEKLDDISNDEKNEFLNKIKQLVETLHAARMEY--KDLREKMKTLARQYKIVLSE 377
Query: 410 NEKEVKEYAQVFREHANKLVEVANLACSISNNEEGVKLVRMAATQIDSLCPQVINAALTL 469
EK + ++ E+ +L ++ +S +K + + Q + A
Sbjct: 378 EEKAFLQKQKIHDENQKQLTFISQKEYFLSQKRVDIKNMEEGLITL-----QELQQATKT 432
Query: 470 AARPQSKVAQDNMD-----VFKDQW------EKQVRVLTEAVDDITSVDDFLSVSENHIL 518
+ Q K+ N++ QW +K R + +I ++ + + +E +
Sbjct: 433 VYQQQIKILSANLERESQRCVITQWKMACLRKKHARWTAKIKAEIQAITEKIQNAEVRRI 492
Query: 519 EDVNKCVIALQE--GDVDTLDRTAGAIRGRAARVIH---IINAEMENYEAGVYTEKVLEA 573
E +N+ QE G V +++ ++ ++ ++ E+ YE E +
Sbjct: 493 ELLNETSFRQQEISGFVAQIEKLTTELKEEEKAFVNKEKMLMKELSKYEEIFVKETQINK 552
Query: 574 TKLLSETVMPRFAEQVEVA----------IEALSANVPQPFEENEFI---------DASR 614
K E + + Q++VA +E LS + +E + + D SR
Sbjct: 553 EK---EEELVEYLPQLQVAEQEYKEKRRKLEELSNIITAQRQEEDLLNNHIFLFTRDFSR 609
Query: 615 LVYDGVRDIRKAVLMIRTPEELEDDSDFE 643
+ + D+++ + +R E ++ FE
Sbjct: 610 YI-SNMEDVKQELQQLRDQESKKNKDHFE 637
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 40.8 bits (94), Expect = 0.006
Identities = 82/375 (21%), Positives = 149/375 (39%), Gaps = 23/375 (6%)
Query: 17 LEIRTLTVERLLEPLVTQVTTLVNTSNKGPSGKKKGRSKKAHVLAASVEQATQNFLEKGE 76
LE +E+ +E + TQ+ L + K + + A E+ Q E+ E
Sbjct: 1523 LEKSKRALEQQVEEMKTQLEELEDELQATEDAKLR-LEVNLQAMKAQFERDLQGRDEQSE 1581
Query: 77 QIAKESQDLKEELVAAVEDVRKQGETMRIASSEFADDPCSSVKRGTMVRAARALLSAVTR 136
+ K+ E+ A +ED RKQ +M +A+ + + ++ + A + A+ +
Sbjct: 1582 EKKKQLVRQVREMEAELEDERKQ-RSMAVAARKKLEMDLKDLE-AHIDSANKNRDEAIKQ 1639
Query: 137 LLIL-ADMADVMRLLSHLKIVEEALEAVKNATNEQDLANRFKEFGKEMVKLN-----YVA 190
L L A M D MR L + E + A + NE+ L K EM++L
Sbjct: 1640 LRKLQAQMKDCMRELDDTRASREEILA-QAKENEKKL----KSMEAEMIQLQEELAAAER 1694
Query: 191 ARRQQELKDPHCRDEMA--AARGALKKNATMLYTASQAFLRHPDVAATRANRDYVFKQVQ 248
A+RQ + + DE+A + +GAL A A L ++ + N + + +++
Sbjct: 1695 AKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEE-ELEEEQGNTELINDRLK 1753
Query: 249 EAIAGISNAAQATSPTDEAKGHTGIGELAAALNEFDNKIILDPMTFSEARFRPSLEERLE 308
+A I Q + + + H E A E NK + + E + +
Sbjct: 1754 KANLQID---QINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYK---A 1807
Query: 309 SIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMNNTGRKEKGDPLNIAIDK 368
SI + A +A D+ + A C VR+ + L + + + DK
Sbjct: 1808 SITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADK 1867
Query: 369 MTKKTRDLRRQLRKA 383
+ + + L+RQL +A
Sbjct: 1868 ASTRLKQLKRQLEEA 1882
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 40.4 bits (93), Expect = 0.008
Identities = 75/398 (18%), Positives = 161/398 (40%), Gaps = 63/398 (15%)
Query: 441 NEEGVKLVRMAATQIDSLCPQVINAALTLAARPQSKVAQDNMDVFKDQWEKQVRVLTEAV 500
+EE L+ + ++ +L +++ T +S V Q+ + ++++ LT V
Sbjct: 1472 HEESQALLDASQKEVQALSTELLKLKNTYE---ESIVGQETLRRENKNLQEEISNLTNQV 1528
Query: 501 DDITSVDDFLSVSENHILEDVNKCVIALQEGDVDTLDRTAGAIRGRAARVIHIINAEMEN 560
+ T +++E +E V K + + TL+ T GA+ ++++H ++E
Sbjct: 1529 REGTK-----NLTE---MEKVKKLIEEEKTEVQVTLEETEGALERNESKILHF---QLEL 1577
Query: 561 YEAGVYTEKVLEATKLLSETVMPRFAEQVEVAIEALSANVPQPFE--------------- 605
EA E+ L + + F + + I++L +++ +
Sbjct: 1578 LEAKAELERKLSE----KDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEED 1633
Query: 606 ----ENEFIDASRLVYDGVRDIRKAVLMIRTPEELEDDSDF------EQEDYDVRSRTSV 655
E + A+R V + + + + + I+ + DDS EQ R + +
Sbjct: 1634 LNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLL 1693
Query: 656 QTEDDQLIAGQSARAIMAQLPQEEKAKIAEQVEIFH-------QEKSKLDAEVAKWDDSG 708
Q+E + L + Q +L +EE + E++ +F+ +K KL+A+VA+
Sbjct: 1694 QSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQKEA 1753
Query: 709 NDIIVLAKQMCMIMMEMTDFTRGKGPLKNTSDVINAAKKIAEAGSRMDKLARAVADQCPD 768
+++ Q C E K + N ++++ + + L R +
Sbjct: 1754 EEVV----QECQNAEEKAK--------KAAIEAANLSEELKKKQDTIAHLERTRENMEQT 1801
Query: 769 SACKQDLLAYLQRIALYCHQLNICSKVKAEVQNLGGEL 806
Q LA +++AL + I K+++ V+ L GEL
Sbjct: 1802 ITDLQKRLAEAEQMALMGSRKQI-QKLESRVRELEGEL 1838
>gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 40.0 bits (92), Expect = 0.010
Identities = 98/505 (19%), Positives = 194/505 (38%), Gaps = 72/505 (14%)
Query: 18 EIRTLTVERLLEPLVTQVTTLVNTSN----KGPSGKKKGRS---------KKAHVLAASV 64
+I+ E ++ L++ V LV N KG +K+ ++AH + +
Sbjct: 329 KIQINNAENTMKSLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKI 388
Query: 65 EQATQNFLEKGEQIAKESQDLKEELVAA---VEDVRKQGE--TMRIASSEFADDPCSSVK 119
++ L GE+ +++ E+LV A +E++R + T R E AD+ +
Sbjct: 389 QEINNKMLYYGEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLS 448
Query: 120 RGTMVRAARALLSAVTRLLILADMADVMRLLSHLKIVEEALEAVKNATNEQDLANRFKEF 179
+ + L TR L + + + L ++EAL+ N + + NR
Sbjct: 449 QAESWQR----LHNETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRAT-- 502
Query: 180 GKEMVKLNYVAARRQQELKDPHCRDEMAAARGALKKNATMLYTASQAFLRHPDV----AA 235
A +R E + R++M +L +A L T D+ +
Sbjct: 503 ---------AARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASG 553
Query: 236 TRANRDYVFKQVQEAIAGISNAAQATSPTDEAKGHTGIGELAAALNEFDNKIILDPMT-- 293
A D ++Q ++ +SN + EA H +L NE K+ M
Sbjct: 554 IYAEIDGAKSELQVKLSNLSNLSH--DLVQEAIDHA--QDLQQEANELSRKLHSSDMNGL 609
Query: 294 FSEARFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMNNT 353
+A ++ E + + +S A A+ + DR V+ + +D SE + N
Sbjct: 610 VQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKD-ESENLLNQ 668
Query: 354 GRKEKGDPLNIAIDKMTKKTRDLRRQL--RKAVMDHISDSFLETNVPLLVLIEAAKSGNE 411
R+ + + + + + +R + L + A+ +SD+ + ++AA+ G+
Sbjct: 669 ARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQ--------LQAAERGDA 720
Query: 412 KEVKEYAQVFREHANK-LVEVANLACSISNN----------------EEGVKLVRMAATQ 454
++ +++ E AN+ +EV ++NN V R A
Sbjct: 721 QQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRN 780
Query: 455 IDSLCPQVINAALTL-AARPQSKVA 478
+ + PQ+++ T+ RP S V+
Sbjct: 781 LTEVVPQLLDQLRTVEQKRPASNVS 805
>gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]
Length = 1823
Score = 40.0 bits (92), Expect = 0.010
Identities = 98/505 (19%), Positives = 194/505 (38%), Gaps = 72/505 (14%)
Query: 18 EIRTLTVERLLEPLVTQVTTLVNTSN----KGPSGKKKGRS---------KKAHVLAASV 64
+I+ E ++ L++ V LV N KG +K+ ++AH + +
Sbjct: 336 KIQINNAENTMKSLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKI 395
Query: 65 EQATQNFLEKGEQIAKESQDLKEELVAA---VEDVRKQGE--TMRIASSEFADDPCSSVK 119
++ L GE+ +++ E+LV A +E++R + T R E AD+ +
Sbjct: 396 QEINNKMLYYGEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLS 455
Query: 120 RGTMVRAARALLSAVTRLLILADMADVMRLLSHLKIVEEALEAVKNATNEQDLANRFKEF 179
+ + L TR L + + + L ++EAL+ N + + NR
Sbjct: 456 QAESWQR----LHNETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRAT-- 509
Query: 180 GKEMVKLNYVAARRQQELKDPHCRDEMAAARGALKKNATMLYTASQAFLRHPDV----AA 235
A +R E + R++M +L +A L T D+ +
Sbjct: 510 ---------AARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASG 560
Query: 236 TRANRDYVFKQVQEAIAGISNAAQATSPTDEAKGHTGIGELAAALNEFDNKIILDPMT-- 293
A D ++Q ++ +SN + EA H +L NE K+ M
Sbjct: 561 IYAEIDGAKSELQVKLSNLSNLSH--DLVQEAIDHA--QDLQQEANELSRKLHSSDMNGL 616
Query: 294 FSEARFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMNNT 353
+A ++ E + + +S A A+ + DR V+ + +D SE + N
Sbjct: 617 VQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKD-ESENLLNQ 675
Query: 354 GRKEKGDPLNIAIDKMTKKTRDLRRQL--RKAVMDHISDSFLETNVPLLVLIEAAKSGNE 411
R+ + + + + + +R + L + A+ +SD+ + ++AA+ G+
Sbjct: 676 ARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQ--------LQAAERGDA 727
Query: 412 KEVKEYAQVFREHANK-LVEVANLACSISNN----------------EEGVKLVRMAATQ 454
++ +++ E AN+ +EV ++NN V R A
Sbjct: 728 QQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRN 787
Query: 455 IDSLCPQVINAALTL-AARPQSKVA 478
+ + PQ+++ T+ RP S V+
Sbjct: 788 LTEVVPQLLDQLRTVEQKRPASNVS 812
>gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 40.0 bits (92), Expect = 0.010
Identities = 98/505 (19%), Positives = 194/505 (38%), Gaps = 72/505 (14%)
Query: 18 EIRTLTVERLLEPLVTQVTTLVNTSN----KGPSGKKKGRS---------KKAHVLAASV 64
+I+ E ++ L++ V LV N KG +K+ ++AH + +
Sbjct: 329 KIQINNAENTMKSLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKI 388
Query: 65 EQATQNFLEKGEQIAKESQDLKEELVAA---VEDVRKQGE--TMRIASSEFADDPCSSVK 119
++ L GE+ +++ E+LV A +E++R + T R E AD+ +
Sbjct: 389 QEINNKMLYYGEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEADEAYELLS 448
Query: 120 RGTMVRAARALLSAVTRLLILADMADVMRLLSHLKIVEEALEAVKNATNEQDLANRFKEF 179
+ + L TR L + + + L ++EAL+ N + + NR
Sbjct: 449 QAESWQR----LHNETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRAT-- 502
Query: 180 GKEMVKLNYVAARRQQELKDPHCRDEMAAARGALKKNATMLYTASQAFLRHPDV----AA 235
A +R E + R++M +L +A L T D+ +
Sbjct: 503 ---------AARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASG 553
Query: 236 TRANRDYVFKQVQEAIAGISNAAQATSPTDEAKGHTGIGELAAALNEFDNKIILDPMT-- 293
A D ++Q ++ +SN + EA H +L NE K+ M
Sbjct: 554 IYAEIDGAKSELQVKLSNLSNLSH--DLVQEAIDHA--QDLQQEANELSRKLHSSDMNGL 609
Query: 294 FSEARFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMNNT 353
+A ++ E + + +S A A+ + DR V+ + +D SE + N
Sbjct: 610 VQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKD-ESENLLNQ 668
Query: 354 GRKEKGDPLNIAIDKMTKKTRDLRRQL--RKAVMDHISDSFLETNVPLLVLIEAAKSGNE 411
R+ + + + + + +R + L + A+ +SD+ + ++AA+ G+
Sbjct: 669 ARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQ--------LQAAERGDA 720
Query: 412 KEVKEYAQVFREHANK-LVEVANLACSISNN----------------EEGVKLVRMAATQ 454
++ +++ E AN+ +EV ++NN V R A
Sbjct: 721 QQRLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRN 780
Query: 455 IDSLCPQVINAALTL-AARPQSKVA 478
+ + PQ+++ T+ RP S V+
Sbjct: 781 LTEVVPQLLDQLRTVEQKRPASNVS 805
>gi|223029410 talin 1 [Homo sapiens]
Length = 2541
Score = 38.1 bits (87), Expect = 0.037
Identities = 86/388 (22%), Positives = 146/388 (37%), Gaps = 76/388 (19%)
Query: 534 DTLDRTAGAIRGRAAR-VIHIINAEMENYEAGVYTEKVLEATKLLSETVMPRFAEQVEVA 592
D L + A A+ AA V+ + ++G+ T+ + AT+ T Q+
Sbjct: 666 DALMQLAKAVASAAAALVLKAKSVAQRTEDSGLQTQVIAAATQCALST------SQLVAC 719
Query: 593 IEALSANVPQPFEENEFIDASRLVYDGVRDIRKAVLMIRTPEELEDDSDFEQEDYDVRSR 652
+ ++ + P + + ++A RLV V A
Sbjct: 720 TKVVAPTISSPVCQEQLVEAGRLVAKAVEGCVSA-------------------------- 753
Query: 653 TSVQTEDDQLIAGQSARAI-----MAQLPQEEKAKI--AEQVEIFHQEKSKLDAEVAKWD 705
+ TED QL+ G A A + +L Q KA A + Q +
Sbjct: 754 SQAATEDGQLLRGVGAAATAVTQALNELLQHVKAHATGAGPAGRYDQATDTILTVTENIF 813
Query: 706 DSGNDIIVLAKQMCMIMMEMTDFTR-------GKGPLKNTSDVINAAKKIAEAGSRMDKL 758
S D + +Q ++ +D G+ L+N+ +++AAK +A+A ++M +
Sbjct: 814 SSMGDAGEMVRQARILAQATSDLVNAIKADAEGESDLENSRKLLSAAKILADATAKMVEA 873
Query: 759 ARAVADQCPDSACKQDLLAYLQRIALYCHQLNICSKVKAEVQNLGGELIVSGLDSATSLI 818
A+ A PDS +Q QR+ L + + A QN + +V L+ A
Sbjct: 874 AKGAAAH-PDSEEQQ------QRLREAAEGLRMAT--NAAAQNAIKKKLVQRLEHAAK-- 922
Query: 819 QAAKNLMNAVVLTVKASYVASTKYQKVYGTAAVNSPVVSWKMKA-PEKKPLVKREKPEEF 877
QAA + + A + AST +A P++ KA E+ PL+
Sbjct: 923 QAAASATQTI---AAAQHAASTP-----KASAGPQPLLVQSCKAVAEQIPLL-------- 966
Query: 878 QTRVRRGSQKKHISPVQALSEFKAMDSF 905
+ RGSQ + SP L+ A SF
Sbjct: 967 -VQGVRGSQAQPDSPSAQLALIAASQSF 993
Score = 33.9 bits (76), Expect = 0.70
Identities = 23/103 (22%), Positives = 49/103 (47%), Gaps = 7/103 (6%)
Query: 66 QATQNFLEKGEQIAKE--SQDLKEELVAAVEDVRKQGETMRIASSEFADDPCSSVKRGTM 123
Q FLE G ++A + SQ+ + ++V+ ++ + + +A+ + DP + + +
Sbjct: 1276 QDFSTFLEAGVEMAGQAPSQEDRAQVVSNLKGISMSSSKLLLAAKALSTDPAAPNLKSQL 1335
Query: 124 VRAARALLSAVTRLLILA-----DMADVMRLLSHLKIVEEALE 161
AARA+ ++ +L+ + + L L+ V E LE
Sbjct: 1336 AAAARAVTDSINQLITMCTQQAPGQKECDNALRELETVRELLE 1378
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 37.4 bits (85), Expect = 0.064
Identities = 111/699 (15%), Positives = 269/699 (38%), Gaps = 60/699 (8%)
Query: 76 EQIAKESQDLK---EELVAAVEDVRKQGETMRIASSEFAD-DPCSSVKRGTMVRAARALL 131
E I E L+ + LV E +R + E M + E D D +++R T L+
Sbjct: 494 ENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLI 553
Query: 132 SAVTRLLILADMADVMRLLSHLKIVEEALEAVKNATNEQDLANRFKEF--GKEMVKLNYV 189
++ L L A+V + + E V+ ++D + +E+ +++ +
Sbjct: 554 HEISNLKNLVKHAEVY----NQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMD 609
Query: 190 AARRQQELKDPHCRDEMAAARGALKKNATMLYTASQAFLRHPDVAATRANRDYV--FKQV 247
+ + ++DP + + +A AFLR ++ ++ +KQ+
Sbjct: 610 LSYSLESIEDPKQMKQTLFDAETVALDAKR----ESAFLRSENLELKEKMKELATTYKQM 665
Query: 248 QEAIAGISNAAQATSPTD---EAKGHTGIGELAAALNEFDNKIILDPMTFSEARFR-PSL 303
+ I + +A E + + E+ + D K+ D + E + L
Sbjct: 666 ENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDL 725
Query: 304 EERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMNNTGRKEK----- 358
++ L + + + + + + +E +R+ +QD E T K+K
Sbjct: 726 QKELNKEVEENEALREEVILLSELKS-LPSEVERLRKEIQDKSEELHIITSEKDKLFSEV 784
Query: 359 ---GDPLNIAIDKMTKKTRDLRR-QLRKAVMDHISDSFLETNVPLLVLIEAAKSGNEKEV 414
+ ++++ K DL Q D +F ++ + NE+
Sbjct: 785 VHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMN 844
Query: 415 KEYAQVFREHANKLVEVANLACSISNN----EEGVKLVRMAATQIDSLCPQVINAALTLA 470
+E + +E + L +S +E + V+ +++ L Q+ N TL
Sbjct: 845 QEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQ 904
Query: 471 ARPQSKVAQDNMDVFKDQWEKQVRVLTEAVDDITSVDDFLSVSENHILEDVNKCVIALQE 530
+ K Q ++V+ LT+ DD+ + + L + + + D++ V
Sbjct: 905 TVEREKTLITEK---LQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTV----N 957
Query: 531 GDVDTLDRTAGAIRG--RAARVIHIINAEM-ENYEAGVYTEKVLEATKLLSETVMPRFAE 587
++DT ++ A+ + I+ + +++ E ++ E+ TK + M +
Sbjct: 958 MNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDK 1017
Query: 588 QVEVA---IEALSANVPQPFEENEFIDASRLVYDGVRDIRKAVLMIRTPEELEDDSDFEQ 644
+ ++ + L+A+V ++NE I+ R ++ +++ + M+ E + + + +
Sbjct: 1018 KQDLEAKNTQTLTADV----KDNEIIEQQRKIFSLIQEKNELQQML---ESVIAEKEQLK 1070
Query: 645 EDYDVRSRTSVQTEDDQLIAGQSARAIMAQLPQEEKAKIAEQVEI------FHQEKSKLD 698
D +++ +++ + G + + QE+ I ++ E+ + + KL
Sbjct: 1071 TDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLK 1130
Query: 699 AEVAKWDDSGNDIIVLAKQMCMIMMEMTDFTRGKGPLKN 737
+ + + ++ + ++M + ++ + K LKN
Sbjct: 1131 EKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKN 1169
>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
Length = 2649
Score = 36.6 bits (83), Expect = 0.11
Identities = 140/718 (19%), Positives = 271/718 (37%), Gaps = 81/718 (11%)
Query: 50 KKGRSKKAHVLAASVEQATQNFLEKGEQIAKESQDLKEELVAAVEDVRKQGETMRIASSE 109
KK +S+ L V +A +N L K ++ ++ K + + R++ ET+ + E
Sbjct: 1151 KKQKSRVEEELP-KVREAAENELRKQQRNVEDISLQKIRAESEAKQYRRELETI-VREKE 1208
Query: 110 FADDPCSSVKRGTMVRAARALLSAVTRLLI-----LADMADVMRLLS-HLKIVEEAL--- 160
A+ V++ T+ A A +AV L+ L + R L HLK + +L
Sbjct: 1209 AAERELERVRQLTI--EAEAKRAAVEENLLNFRNQLEENTFTRRTLEDHLKRKDLSLNDL 1266
Query: 161 ---------EAVKNATNEQDLANRFKEFGKEMVKLNYVAARRQQELK--DPHCRDEMAAA 209
E + NE++L K+ K++ VA ++ +E + + R ++
Sbjct: 1267 EQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAFQKQVAEKQLKEKQKIELEARRKITEI 1326
Query: 210 RGALKKNATMLYTASQAF-------------------LRHPDVAATRANRDYVFKQVQEA 250
+ ++NA + +QA L+ T ANR +Q
Sbjct: 1327 QYTCRENALPVCPITQATSCRAVTGLQQEHDKQKAEELKQQVDELTAANRKA--EQDMRE 1384
Query: 251 IAGISNAAQATSPTDEAKGHTGIGELAAALNEFDN-----KIILDPMTFSEARFRPSLEE 305
+ NA Q + E K L L+E +N K+ L+ +E + L E
Sbjct: 1385 LTYELNALQLEKTSSEEKARL----LKDKLDETNNTLRCLKLELERKDQAEKGYSQQLRE 1440
Query: 306 ---RLESIISGA--ALMADSSCTRDDRRERIVAEC-NAVRQALQDLLSEYMNNTGRKEKG 359
+L A A+ S + R ++ E N + LQ + EK
Sbjct: 1441 LGRQLNQTTGKAEEAMQEASDLKKIKRNYQLELESLNHEKGKLQREVDRITRAHAVAEKN 1500
Query: 360 -DPLNIAIDKMTKKTRDLRRQLRKAVMDHISDSFLETNVPLLVLIEAAKSGNEK--EVKE 416
LN I + R Q+ + DH+ + F +++ LL I+A K N+K + E
Sbjct: 1501 IQHLNSQIHSFRDEKELERLQICQRKSDHLKEQFEKSHEQLLQNIKAEKENNDKIQRLNE 1560
Query: 417 YAQVFREHANKLVEVANLACSISNNEEGVKLVRMAATQIDSLCPQVINAALTLAARPQSK 476
+ E A L + + NNE + + R+ A + + + A + Q+
Sbjct: 1561 ELEKSNECAEMLKQKVE-ELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEALKIQAD 1619
Query: 477 VAQDNMDVFKDQWEKQVRVLTEAVDDITSVDDFLSVSENHILEDVNKC-----VIALQEG 531
+D + + KQ + + I +++ L+ S+N + E KC +I +
Sbjct: 1620 GFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNIIIQNTKK 1679
Query: 532 DVDTLDRTAGAI---RGRAARVIHIINAEMENYEAGVYTEKVLEATKLLSETVMPRFAEQ 588
+V L+ A + R + + + A+++ E +KV + L +T+ + +
Sbjct: 1680 EVRNLNAELNASKEEKRRGEQKVQLQQAQVQ--ELNNRLKKVQDELHL--KTIEEQMTHR 1735
Query: 589 VEVAIEALSANVPQPFEE-----NEFIDASRLVYDGVRDIRKAVLMIRTPEELEDDSDFE 643
V + S Q EE + +++ + + + IR + ++ ++
Sbjct: 1736 KMVLFQEESGKFKQSAEEFRKKMEKLMESKVITENDISGIRLDFVSLQQENSRAQENAKL 1795
Query: 644 QEDYDVRSRTSVQTEDDQLIAGQSARAIMAQLPQEEKAKIAEQVEIFHQEKSKLDAEV 701
E +Q +Q+ GQ A Q Q+ + ++ Q K K+D ++
Sbjct: 1796 CETNIKELERQLQQYREQMQQGQHMEANHYQKCQKLEDELIAQKREVENLKQKMDQQI 1853
>gi|110347568 centrosomal protein 152kDa [Homo sapiens]
Length = 1654
Score = 35.8 bits (81), Expect = 0.19
Identities = 76/430 (17%), Positives = 178/430 (41%), Gaps = 49/430 (11%)
Query: 356 KEKGDPLNIAIDKMTKKTRDLRRQLRKAVMDHISDSFLETNVPLLVLIEAAKSGNEKEVK 415
K K L I+K+ + R +R + V+ I D + L + ++G E+E++
Sbjct: 246 KAKERQLENLIEKLNESERQIRYLNHQLVI--IKDEKDGLTLSLRESQKLFQNGKEREIQ 303
Query: 416 EYAQVFREHANKLVEVANLACSISNNEEGVKLVRMAATQIDSLCPQVINA----ALTLAA 471
AQ+ K +E A + N E+ +K R ++SL Q+++ +L A
Sbjct: 304 LEAQI------KALETQIQALKV-NEEQMIKKSRTTEMALESLKQQLVDLHHSESLQRAR 356
Query: 472 RPQSKVAQDNMDVFKDQWEKQVRVLTEAVDDITSVDDFLSVSENHILE-DVNKCVIALQE 530
+ +++Q + L V + +D S ++H+ + + N+ I L++
Sbjct: 357 EQHESIVMGLTKKYEEQVLSLQKNLDATVTALKEQEDICSRLKDHVKQLERNQEAIKLEK 416
Query: 531 GDV-DTLDRTAGAIRGRAARVIH------IINAEMENYEAGVYTEKVLEATKLLSETVMP 583
++ + L R+ + + A ++ + + + +A K L E +
Sbjct: 417 TEIINKLTRSLEESQKQCAHLLQSGSVQEVAQLQFQLQQAQKAHAMSANMNKALQEE-LT 475
Query: 584 RFAEQVEVAIEALSANVPQPFEENEF-IDASRLVYD-GVRDIR-KAVLMIRTPEELEDDS 640
+++ + A + E E I+ + D G++ + K + +E + +
Sbjct: 476 ELKDEISLYESAAKLGIHPSDSEGELNIELTESYVDLGIKKVNWKKSKVTSIVQEEDPNE 535
Query: 641 DFEQEDYDVRSRTSVQTEDDQLIAGQSARAIMAQLPQEEKAKIAEQVEIFHQEK------ 694
+ ++++ ++ + VQ +L+ S + + Q + +++E HQ K
Sbjct: 536 ELSKDEFILKLKAEVQ----RLLGSNSMKRHLVSQLQNDLKDCHKKIEDLHQVKKDEKSI 591
Query: 695 ---SKLD-AEVAK---WDDSG------NDIIVLAKQMCMIMMEMTDFTRGKGPLKNTS-D 740
+K D +E K W +S +DI++L ++ ++ + + +G L+NT+ D
Sbjct: 592 EVETKTDTSEKPKNQLWPESSTSDVVRDDILLLKNEIQVLQQQNQELKETEGKLRNTNQD 651
Query: 741 VINAAKKIAE 750
+ N +++ +
Sbjct: 652 LCNQMRQMVQ 661
>gi|134152674 rabaptin, RAB GTPase binding effector protein 1
isoform 2 [Homo sapiens]
Length = 829
Score = 35.8 bits (81), Expect = 0.19
Identities = 67/315 (21%), Positives = 124/315 (39%), Gaps = 49/315 (15%)
Query: 365 AIDKMTKKTRDLRRQLRKAVMDHISDSFLETNVPLLVLIEAAKSGNEKEVKEYAQVFREH 424
AID++ ++ R+ L+ + + + D + ++ L E+E ++AQ +RE
Sbjct: 102 AIDEVKRQWREEVASLQAVMKETVRDYEHQFHLRL-----------EQERTQWAQ-YRES 149
Query: 425 ANKLVEVANLACSISNNEEGVKLVR-MAATQIDSLCPQVINAALTLAARPQSKVAQDNMD 483
A + E+A+L +S +E L M Q D+ L P K +
Sbjct: 150 AER--EIADLRRRLSEGQEEENLENEMKKAQEDA-------EKLRSVVMPMEK----EIA 196
Query: 484 VFKDQWEKQVRVLTEAVDDITSVDDFLSVSENHILEDVNKC------VIALQEGDVDTLD 537
KD+ LTEA D I ++ NH LE C +A+ L
Sbjct: 197 ALKDK-------LTEAEDKIKELEASKVKELNHYLEAEKSCRTDLEMYVAVLNTQKSVLQ 249
Query: 538 RTAGAIRGRAARVIHIINAEMENYEAGVYTEKVLEATKLLSETVMPRFAEQVEVAIEALS 597
A +R V H++ E + + +T + L S+ ++ R +++E+ + +
Sbjct: 250 EDAEKLRKELHEVCHLLEQERQQHNQLKHTWQKANDQFLESQRLLMRDMQRMEIVLTSEQ 309
Query: 598 ANVPQPFEENEFIDASRLVYDGVRDIRKA---------VLMIRTPEELEDDSDFEQEDYD 648
+ ++ + D + + +D +KA V+ T EE E+E D
Sbjct: 310 LRQVEELKKKDQEDDEQQRLNKRKDHKKADVEEEIKIPVVCALTQEESSAQLSNEEEHLD 369
Query: 649 VRSRTSVQTEDDQLI 663
+R SV + D L+
Sbjct: 370 -STRGSVHSLDAGLL 383
>gi|31377798 rabaptin, RAB GTPase binding effector protein 1 isoform
1 [Homo sapiens]
Length = 862
Score = 35.8 bits (81), Expect = 0.19
Identities = 67/315 (21%), Positives = 124/315 (39%), Gaps = 49/315 (15%)
Query: 365 AIDKMTKKTRDLRRQLRKAVMDHISDSFLETNVPLLVLIEAAKSGNEKEVKEYAQVFREH 424
AID++ ++ R+ L+ + + + D + ++ L E+E ++AQ +RE
Sbjct: 102 AIDEVKRQWREEVASLQAVMKETVRDYEHQFHLRL-----------EQERTQWAQ-YRES 149
Query: 425 ANKLVEVANLACSISNNEEGVKLVR-MAATQIDSLCPQVINAALTLAARPQSKVAQDNMD 483
A + E+A+L +S +E L M Q D+ L P K +
Sbjct: 150 AER--EIADLRRRLSEGQEEENLENEMKKAQEDA-------EKLRSVVMPMEK----EIA 196
Query: 484 VFKDQWEKQVRVLTEAVDDITSVDDFLSVSENHILEDVNKC------VIALQEGDVDTLD 537
KD+ LTEA D I ++ NH LE C +A+ L
Sbjct: 197 ALKDK-------LTEAEDKIKELEASKVKELNHYLEAEKSCRTDLEMYVAVLNTQKSVLQ 249
Query: 538 RTAGAIRGRAARVIHIINAEMENYEAGVYTEKVLEATKLLSETVMPRFAEQVEVAIEALS 597
A +R V H++ E + + +T + L S+ ++ R +++E+ + +
Sbjct: 250 EDAEKLRKELHEVCHLLEQERQQHNQLKHTWQKANDQFLESQRLLMRDMQRMEIVLTSEQ 309
Query: 598 ANVPQPFEENEFIDASRLVYDGVRDIRKA---------VLMIRTPEELEDDSDFEQEDYD 648
+ ++ + D + + +D +KA V+ T EE E+E D
Sbjct: 310 LRQVEELKKKDQEDDEQQRLNKRKDHKKADVEEEIKIPVVCALTQEESSAQLSNEEEHLD 369
Query: 649 VRSRTSVQTEDDQLI 663
+R SV + D L+
Sbjct: 370 -STRGSVHSLDAGLL 383
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 35.4 bits (80), Expect = 0.24
Identities = 56/262 (21%), Positives = 111/262 (42%), Gaps = 36/262 (13%)
Query: 329 ERIVAECNAVRQALQDLLS--EYMNNTGRKE----KGDPLNIAIDKMTKKTRDLRRQLRK 382
ER A A +QAL+ L E NN + + + +++ T +T++ + Q+
Sbjct: 1052 ERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVEN 1111
Query: 383 AVMDHISDSFLETNVPLLVLIEAAKSGNEKEVKEYAQVFREHANKLVEVANLACSISNNE 442
+ ++ S S + N LL+ + ++ NE +KE RE L + I ++E
Sbjct: 1112 STLNSQSTSLMNQNAQLLIQQSSLENENESVIKE-----REDLKSLYD-----SLIKDHE 1161
Query: 443 EGVKLVRMAATQIDSLCPQVINAALTLAARPQSKVAQDNMDVFKDQWEKQVRVLTEAVDD 502
+ L A++ +SL ++ K A N++V E + L +
Sbjct: 1162 KLELLHERQASEYESL----------ISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQ 1211
Query: 503 ITSVDDFLSV-SENHILEDVNKCVIALQE----GDVDTLDRTAGAIRGRAARVIHIINAE 557
+ ++ L V E +LE+ N +A + G+ D L+ T + + ++ +
Sbjct: 1212 LEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQL----LKETEVLQTD 1267
Query: 558 MENYEAGVYTEKVLEATKLLSE 579
+N ++ + K LE T+L +E
Sbjct: 1268 HKNLKSLLNNSK-LEQTRLEAE 1288
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.128 0.346
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,058,949
Number of Sequences: 37866
Number of extensions: 1114560
Number of successful extensions: 4972
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 81
Number of HSP's that attempted gapping in prelim test: 4828
Number of HSP's gapped (non-prelim): 212
length of query: 905
length of database: 18,247,518
effective HSP length: 111
effective length of query: 794
effective length of database: 14,044,392
effective search space: 11151247248
effective search space used: 11151247248
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.