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Search of human proteins with 54859560
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54859560 transmembrane 4 superfamily member 17 isoform a
[Homo sapiens]
(332 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54859560 transmembrane 4 superfamily member 17 isoform a [Hom... 705 0.0
gi|50511934 transmembrane 4 superfamily member 17 isoform b [Hom... 694 0.0
gi|54859505 transmembrane 4 superfamily member 17 isoform c [Hom... 553 e-158
gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens] 460 e-130
gi|190194420 tetraspanin 14 isoform 1 [Homo sapiens] 329 2e-90
gi|30425534 tetraspanin 33 [Homo sapiens] 230 1e-60
gi|6912530 transmembrane 4 superfamily member 15 [Homo sapiens] 164 1e-40
gi|190341022 tetraspanin 14 isoform 2 [Homo sapiens] 157 1e-38
gi|119120834 tetraspanin 10 [Homo sapiens] 143 2e-34
gi|4504813 CD82 antigen isoform 1 [Homo sapiens] 114 1e-25
gi|21265104 tetraspanin 7 [Homo sapiens] 112 4e-25
gi|4502679 CD63 antigen isoform A [Homo sapiens] 112 5e-25
gi|42476204 tetraspanin 18 isoform 2 [Homo sapiens] 106 3e-23
gi|5729941 tetraspanin 9 [Homo sapiens] 106 3e-23
gi|91199546 CD63 antigen isoform B [Homo sapiens] 106 3e-23
gi|87159824 CD151 antigen [Homo sapiens] 105 7e-23
gi|87159822 CD151 antigen [Homo sapiens] 105 7e-23
gi|21237751 CD151 antigen [Homo sapiens] 105 7e-23
gi|21237748 CD151 antigen [Homo sapiens] 105 7e-23
gi|68800005 tetraspanin 4 isoform a [Homo sapiens] 104 1e-22
gi|4507543 tetraspanin 4 isoform a [Homo sapiens] 104 1e-22
gi|68800018 tetraspanin 4 isoform a [Homo sapiens] 104 1e-22
gi|68800024 tetraspanin 4 isoform a [Homo sapiens] 104 1e-22
gi|68800011 tetraspanin 4 isoform a [Homo sapiens] 104 1e-22
gi|68799997 tetraspanin 4 isoform a [Homo sapiens] 104 1e-22
gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens] 101 1e-21
gi|72534746 tetraspanin 18 isoform 1 [Homo sapiens] 100 2e-21
gi|67782354 CD82 antigen isoform 2 [Homo sapiens] 99 7e-21
gi|122937466 tetraspanin 11 [Homo sapiens] 99 7e-21
gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens] 98 1e-20
>gi|54859560 transmembrane 4 superfamily member 17 isoform a [Homo
sapiens]
Length = 332
Score = 705 bits (1820), Expect = 0.0
Identities = 332/332 (100%), Positives = 332/332 (100%)
Query: 1 MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG 60
MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG
Sbjct: 1 MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG 60
Query: 61 LDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDW 120
LDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDW
Sbjct: 61 LDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDW 120
Query: 121 IRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRE 180
IRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRE
Sbjct: 121 IRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRE 180
Query: 181 RCGVPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIV 240
RCGVPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIV
Sbjct: 181 RCGVPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIV 240
Query: 241 VAGVFMGIALLQIFGICLAQNLVSDIKAVKANWSKWNDDFENHWLTPTISEVLSTAGPQQ 300
VAGVFMGIALLQIFGICLAQNLVSDIKAVKANWSKWNDDFENHWLTPTISEVLSTAGPQQ
Sbjct: 241 VAGVFMGIALLQIFGICLAQNLVSDIKAVKANWSKWNDDFENHWLTPTISEVLSTAGPQQ 300
Query: 301 NSLTGAPGPAPPSRHVFFGLGGLYPEPTFKNW 332
NSLTGAPGPAPPSRHVFFGLGGLYPEPTFKNW
Sbjct: 301 NSLTGAPGPAPPSRHVFFGLGGLYPEPTFKNW 332
>gi|50511934 transmembrane 4 superfamily member 17 isoform b [Homo
sapiens]
Length = 329
Score = 694 bits (1791), Expect = 0.0
Identities = 329/332 (99%), Positives = 329/332 (99%), Gaps = 3/332 (0%)
Query: 1 MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG 60
MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG
Sbjct: 1 MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG 60
Query: 61 LDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDW 120
LDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDW
Sbjct: 61 LDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDW 120
Query: 121 IRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRE 180
IRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRE
Sbjct: 121 IRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRE 180
Query: 181 RCGVPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIV 240
RCGVPFSCCVRDPAEDVLNTQCGYDVRLKL ELEQQGFIHTKGCVGQFEKWLQDNLIV
Sbjct: 181 RCGVPFSCCVRDPAEDVLNTQCGYDVRLKL---ELEQQGFIHTKGCVGQFEKWLQDNLIV 237
Query: 241 VAGVFMGIALLQIFGICLAQNLVSDIKAVKANWSKWNDDFENHWLTPTISEVLSTAGPQQ 300
VAGVFMGIALLQIFGICLAQNLVSDIKAVKANWSKWNDDFENHWLTPTISEVLSTAGPQQ
Sbjct: 238 VAGVFMGIALLQIFGICLAQNLVSDIKAVKANWSKWNDDFENHWLTPTISEVLSTAGPQQ 297
Query: 301 NSLTGAPGPAPPSRHVFFGLGGLYPEPTFKNW 332
NSLTGAPGPAPPSRHVFFGLGGLYPEPTFKNW
Sbjct: 298 NSLTGAPGPAPPSRHVFFGLGGLYPEPTFKNW 329
>gi|54859505 transmembrane 4 superfamily member 17 isoform c [Homo
sapiens]
Length = 266
Score = 553 bits (1426), Expect = e-158
Identities = 262/262 (100%), Positives = 262/262 (100%)
Query: 1 MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG 60
MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG
Sbjct: 1 MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG 60
Query: 61 LDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDW 120
LDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDW
Sbjct: 61 LDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDW 120
Query: 121 IRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRE 180
IRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRE
Sbjct: 121 IRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRE 180
Query: 181 RCGVPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIV 240
RCGVPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIV
Sbjct: 181 RCGVPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIV 240
Query: 241 VAGVFMGIALLQIFGICLAQNL 262
VAGVFMGIALLQIFGICLAQNL
Sbjct: 241 VAGVFMGIALLQIFGICLAQNL 262
>gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens]
Length = 268
Score = 460 bits (1183), Expect = e-130
Identities = 213/273 (78%), Positives = 239/273 (87%), Gaps = 5/273 (1%)
Query: 1 MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG 60
M GKH ++ PEV CC KYF+FGFN++FW LG FL IGLWAW EKGVLSNIS++TDLGG
Sbjct: 1 MSGKH--YKGPEVSCCIKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSNISSITDLGG 58
Query: 61 LDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDW 120
DPVWLF+VVGGVM +LGFAGCIGALRENTFLLKFFSVFLG+IFFLEL G+LAFVFKDW
Sbjct: 59 FDPVWLFLVVGGVMFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVFKDW 118
Query: 121 IRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRE 180
I+DQL FINNN++AYRDDIDLQNLIDF QEYW CCGA G +DWNLNIYFNCTD N SRE
Sbjct: 119 IKDQLYFFINNNIRAYRDDIDLQNLIDFTQEYWQCCGAFGADDWNLNIYFNCTDSNASRE 178
Query: 181 RCGVPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIV 240
RCGVPFSCC +DPAEDV+NTQCGYD R K E++QQ I+TKGCV QFEKWLQDNL +
Sbjct: 179 RCGVPFSCCTKDPAEDVINTQCGYDARQK---PEVDQQIVIYTKGCVPQFEKWLQDNLTI 235
Query: 241 VAGVFMGIALLQIFGICLAQNLVSDIKAVKANW 273
VAG+F+GIALLQIFGICLAQNLVSDI+AV+A+W
Sbjct: 236 VAGIFIGIALLQIFGICLAQNLVSDIEAVRASW 268
>gi|190194420 tetraspanin 14 isoform 1 [Homo sapiens]
Length = 270
Score = 329 bits (844), Expect = 2e-90
Identities = 154/267 (57%), Positives = 200/267 (74%), Gaps = 3/267 (1%)
Query: 5 HQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPV 64
+ + +V C KY LF +NI+FW+ G +FL +GLWAW EKGVLS+++ +T + G+DPV
Sbjct: 3 YYRYSNAKVSCWYKYLLFSYNIIFWLAGVVFLGVGLWAWSEKGVLSDLTKVTRMHGIDPV 62
Query: 65 WLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQ 124
L ++VG VM LGFAGC+GALREN LL FF + LIFFLELA +LAF+F+DW+RD+
Sbjct: 63 VLVLMVGVVMFTLGFAGCVGALRENICLLNFFCGTIVLIFFLELAVAVLAFLFQDWVRDR 122
Query: 125 LNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGV 184
F +N+K+YRDDIDLQNLID Q+ CCGA GP DW+LN+YFNC+ + SRE+CGV
Sbjct: 123 FREFFESNIKSYRDDIDLQNLIDSLQKANQCCGAYGPEDWDLNVYFNCSGASYSREKCGV 182
Query: 185 PFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGV 244
PFSCCV DPA+ V+NTQCGYDVR++L + + I TKGC+ E WL N+ +VAGV
Sbjct: 183 PFSCCVPDPAQKVVNTQCGYDVRIQL---KSKWDESIFTKGCIQALESWLPRNIYIVAGV 239
Query: 245 FMGIALLQIFGICLAQNLVSDIKAVKA 271
F+ I+LLQIFGI LA+ L+SDI+AVKA
Sbjct: 240 FIAISLLQIFGIFLARTLISDIEAVKA 266
>gi|30425534 tetraspanin 33 [Homo sapiens]
Length = 283
Score = 230 bits (587), Expect = 1e-60
Identities = 115/250 (46%), Positives = 164/250 (65%), Gaps = 7/250 (2%)
Query: 18 KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVL 77
KY LF FN++FWV+ + +A+G++A K + ++ L +DP L +VVG +M +L
Sbjct: 23 KYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACLA----VDPAILLIVVGVLMFLL 78
Query: 78 GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAYR 137
F GCIG+LREN LL+ FS+ L +F L+LA GIL FVF D R +++ INN + YR
Sbjct: 79 TFCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHYR 138
Query: 138 DDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAEDV 197
DD+DLQNLIDF Q+ +SCCG DW+ N+YFNC++ NPSRERC VP+SCC+ P + V
Sbjct: 139 DDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQAV 198
Query: 198 LNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFGIC 257
+NT CG ++ LE I+T GC+ + W+ NL ++ GV +G+A+ Q+ GI
Sbjct: 199 INTMCGQGMQ---AFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGIL 255
Query: 258 LAQNLVSDIK 267
L+Q LV+ IK
Sbjct: 256 LSQILVNQIK 265
>gi|6912530 transmembrane 4 superfamily member 15 [Homo sapiens]
Length = 294
Score = 164 bits (414), Expect = 1e-40
Identities = 82/252 (32%), Positives = 141/252 (55%), Gaps = 10/252 (3%)
Query: 18 KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVL 77
K+ L ++ VFW++GAL L++G++A E+ + + L P + +++G VM ++
Sbjct: 21 KFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAF----LAPAIILILLGVVMFMV 76
Query: 78 GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAYR 137
F G + +LR+N +LL+ F LG+ +EL G++A F++ D LN I ++ Y
Sbjct: 77 SFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYY 136
Query: 138 DDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAEDV 197
DD+D +N++DF Q+ + CCG DW+ N Y +C+ P CGVP++CC+R+ E V
Sbjct: 137 DDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCS--APGPLACGVPYTCCIRNTTE-V 193
Query: 198 LNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFGIC 257
+NT CGY + + Q I+ +GC W DN ++AG+ +GI L Q G+
Sbjct: 194 VNTMCGYKT---IDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVL 250
Query: 258 LAQNLVSDIKAV 269
L ++ ++ +
Sbjct: 251 LTLLYITRVEDI 262
>gi|190341022 tetraspanin 14 isoform 2 [Homo sapiens]
Length = 147
Score = 157 bits (397), Expect = 1e-38
Identities = 73/121 (60%), Positives = 94/121 (77%), Gaps = 4/121 (3%)
Query: 152 YWS-CCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAEDVLNTQCGYDVRLKL 210
+W+ CCGA GP DW+LN+YFNC+ + SRE+CGVPFSCCV DPA+ V+NTQCGYDVR++L
Sbjct: 26 FWNQCCGAYGPEDWDLNVYFNCSGASYSREKCGVPFSCCVPDPAQKVVNTQCGYDVRIQL 85
Query: 211 VRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFGICLAQNLVSDIKAVK 270
+ + I TKGC+ E WL N+ +VAGVF+ I+LLQIFGI LA+ L+SDI+AVK
Sbjct: 86 ---KSKWDESIFTKGCIQALESWLPRNIYIVAGVFIAISLLQIFGIFLARTLISDIEAVK 142
Query: 271 A 271
A
Sbjct: 143 A 143
Score = 30.4 bits (67), Expect = 2.3
Identities = 10/25 (40%), Positives = 15/25 (60%)
Query: 5 HQHFQEPEVGCCGKYFLFGFNIVFW 29
+ + +V C KY LF +NI+FW
Sbjct: 3 YYRYSNAKVSCWYKYLLFSYNIIFW 27
>gi|119120834 tetraspanin 10 [Homo sapiens]
Length = 355
Score = 143 bits (361), Expect = 2e-34
Identities = 107/304 (35%), Positives = 147/304 (48%), Gaps = 29/304 (9%)
Query: 16 CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG---LDPVWLFVVVGG 72
C KY +F N F +LG L LAIGLW KG L + DLGG DP+ + G
Sbjct: 75 CVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGS-----DLGGPLPADPMLGLALGGL 129
Query: 73 VMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNN 132
V+S + AG +GAL ENT LL+ FS + LE G L ++D L +
Sbjct: 130 VVSAVSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVA 189
Query: 133 VKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRD 192
+ Y+DD DL+ L+D Q CCGA DW N+YFNC+ +P + C +P SCC+ D
Sbjct: 190 IAHYQDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCS--SPGVQACSLPASCCI-D 246
Query: 193 PAED--VLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIAL 250
P ED +N QCG+ V L+L Q ++ +GC +WL+ NL G + + L
Sbjct: 247 PREDGASVNDQCGFGV-LRLDAD--AAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVL 303
Query: 251 LQIFGICLAQNLVSDIKAVKANWSKWNDDFENHWLTPTISEVLSTAGPQQNSLTGAPGPA 310
LQ + LA L+ + A + + + AGPQ S GAP A
Sbjct: 304 LQGAELLLAARLLGALAARRG--AAYGPGARGE----------DRAGPQSPS-PGAPPAA 350
Query: 311 PPSR 314
P+R
Sbjct: 351 KPAR 354
>gi|4504813 CD82 antigen isoform 1 [Homo sapiens]
Length = 267
Score = 114 bits (285), Expect = 1e-25
Identities = 71/257 (27%), Positives = 130/257 (50%), Gaps = 16/257 (6%)
Query: 18 KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVL 77
KYFLF FN++F++LGA+ L G+W +K ++ + ++F+ VG V ++
Sbjct: 10 KYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFIGVGAVTMLM 69
Query: 78 GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAY- 136
GF GCIGA+ E LL + FL LI ++ G L + ++ ++ + ++ Y
Sbjct: 70 GFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGIVTELIRDYN 129
Query: 137 --RDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPA 194
R+D LQ+ D+ Q CCG +W N +R P SC V+
Sbjct: 130 SSRED-SLQDAWDYVQAQVKCCGWVSFYNWTDNAEL------MNRPEVTYPCSCEVKGEE 182
Query: 195 EDVLNTQCGY--DVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQ 252
++ L+ + G+ + G + ++ +GC+ + + WLQ+NL ++ GV +G+A+++
Sbjct: 183 DNSLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAIIE 242
Query: 253 IFG----ICLAQNLVSD 265
+ G ICL +++ S+
Sbjct: 243 LLGMVLSICLCRHVHSE 259
>gi|21265104 tetraspanin 7 [Homo sapiens]
Length = 249
Score = 112 bits (281), Expect = 4e-25
Identities = 67/244 (27%), Positives = 115/244 (47%), Gaps = 23/244 (9%)
Query: 16 CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMS 75
C K L ++ VFW+ G + LA+G+W K L +L + ++ + G +
Sbjct: 14 CLKTLLIIYSFVFWITGVILLAVGVWG---KLTLGTYISLIAENSTNAPYVLIGTGTTIV 70
Query: 76 VLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKA 135
V G GC R + ++LK +++FL L+F EL GI FVF+ I+D + ++
Sbjct: 71 VFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQT 130
Query: 136 YRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAE 195
Y + + +D Q SCCG + +W+ + YF G+P SCC+ E
Sbjct: 131 YNGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYF---------LEHGIPPSCCMN---E 178
Query: 196 DVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFG 255
N Q +++ + + ++ KGC +++ N+ ++AGV GIA Q+ G
Sbjct: 179 TDCNPQDLHNLTVAATK--------VNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIG 230
Query: 256 ICLA 259
+ LA
Sbjct: 231 MLLA 234
>gi|4502679 CD63 antigen isoform A [Homo sapiens]
Length = 238
Score = 112 bits (280), Expect = 5e-25
Identities = 77/255 (30%), Positives = 122/255 (47%), Gaps = 32/255 (12%)
Query: 16 CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSN--ISALTDLGGLDPVWLFVVVGGV 73
C K+ L+ + F +A+G+ G + VLS I T G L PV + + VG
Sbjct: 9 CVKFLLYVLLLAFCACAVGLIAVGV---GAQLVLSQTIIQGATP-GSLLPV-VIIAVGVF 63
Query: 74 MSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNV 133
+ ++ F GC GA +EN L+ F++FL LI +E+A I +VF+D + + N +
Sbjct: 64 LFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQM 123
Query: 134 KAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDP 193
+ Y + +++D Q + CCGA DW + PS + VP SCC+
Sbjct: 124 ENYPKNNHTASILDRMQADFKCCGAANYTDW---------EKIPSMSKNRVPDSCCIN-- 172
Query: 194 AEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQI 253
+ CG + K IH +GCV + WL+ N++VVA +GIA +++
Sbjct: 173 ----VTVGCGINFNEKA----------IHKEGCVEKIGGWLRKNVLVVAAAALGIAFVEV 218
Query: 254 FGICLAQNLVSDIKA 268
GI A LV I++
Sbjct: 219 LGIVFACCLVKSIRS 233
>gi|42476204 tetraspanin 18 isoform 2 [Homo sapiens]
Length = 248
Score = 106 bits (265), Expect = 3e-23
Identities = 75/259 (28%), Positives = 119/259 (45%), Gaps = 25/259 (9%)
Query: 16 CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMS 75
C KY +F FN ++ GA LAIG+W + I A L L ++ + +GG++
Sbjct: 8 CMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLL-LTGAYILLAMGGLLF 66
Query: 76 VLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKA 135
+LGF GC GA+REN LL FF +F+ +IF EL+ ILAF+F++ + + F K
Sbjct: 67 LLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTRE--FFTKELTKH 124
Query: 136 YRDDIDLQNLIDFAQEYWS-------CCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSC 188
Y+ + D D W+ CCG GP D+ F L+ VP +C
Sbjct: 125 YQGNND----TDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEE----VPEAC 176
Query: 189 CVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGI 248
C R+P Q V L L + F++ +GC + + + + +G+
Sbjct: 177 CRREP-------QSRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGV 229
Query: 249 ALLQIFGICLAQNLVSDIK 267
+++F + A L I+
Sbjct: 230 LAIELFAMIFAMCLFRGIQ 248
>gi|5729941 tetraspanin 9 [Homo sapiens]
Length = 239
Score = 106 bits (264), Expect = 3e-23
Identities = 71/254 (27%), Positives = 109/254 (42%), Gaps = 32/254 (12%)
Query: 15 CCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVM 74
CC KY +F FN++FW+ G L +G+W +G + S L L + +G ++
Sbjct: 7 CCLKYMMFLFNLIFWLCGCGLLGVGIWLSVSQGNFATFSP--SFPSLSAANLVIAIGTIV 64
Query: 75 SVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVK 134
V GF GC+GA++EN LL F + L +I EL IL FV+ D + + + +
Sbjct: 65 MVTGFLGCLGAIKENKCLLLSFFIVLLVILLAELILLILFFVYMDKVNENAKKDLKEGLL 124
Query: 135 AY--RDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRD 192
Y +++ L+N + Q CCG DW P VP CC+ +
Sbjct: 125 LYHTENNVGLKNAWNIIQAEMRCCGVTDYTDW-----------YPVLGENTVPDRCCMEN 173
Query: 193 PAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQ 252
+ CG + L R GC + + W DN V+ V M I ++Q
Sbjct: 174 ------SQGCGRNATTPLWR-----------TGCYEKVKMWFDDNKHVLGTVGMCILIMQ 216
Query: 253 IFGICLAQNLVSDI 266
I G+ + L I
Sbjct: 217 ILGMAFSMTLFQHI 230
>gi|91199546 CD63 antigen isoform B [Homo sapiens]
Length = 236
Score = 106 bits (264), Expect = 3e-23
Identities = 75/253 (29%), Positives = 120/253 (47%), Gaps = 34/253 (13%)
Query: 16 CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSN--ISALTDLGGLDPVWLFVVVGGV 73
C K+ L+ + F +A+G+ G + VLS I T G L PV + + VG
Sbjct: 9 CVKFLLYVLLLAFCACAVGLIAVGV---GAQLVLSQTIIQGATP-GSLLPV-VIIAVGVF 63
Query: 74 MSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNV 133
+ ++ F GC GA +EN L+ F++FL LI +E+A I +VF+D + + N +
Sbjct: 64 LFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQM 123
Query: 134 KAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDP 193
+ Y + +++D Q + CCGA DW + PS + VP SCC+
Sbjct: 124 ENYPKNNHTASILDRMQADFKCCGAANYTDW---------EKIPSMSKNRVPDSCCIN-- 172
Query: 194 AEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQ- 252
+ CG + K IH +GCV + WL+ N++VVA +GIA +
Sbjct: 173 ----VTVGCGINFNEKA----------IHKEGCVEKIGGWLRKNVLVVAAAALGIAFVLG 218
Query: 253 -IFGICLAQNLVS 264
+F CL +++ S
Sbjct: 219 IVFACCLVKSIRS 231
>gi|87159824 CD151 antigen [Homo sapiens]
Length = 253
Score = 105 bits (261), Expect = 7e-23
Identities = 79/267 (29%), Positives = 125/267 (46%), Gaps = 34/267 (12%)
Query: 8 FQEPEVGC---CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPV 64
F E + C C KY LF +N FW+ G +A+G+W K IS L L
Sbjct: 4 FNEKKTTCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKS--DYISLLASGTYLATA 61
Query: 65 WLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQ 124
++ VV G V+ V G GC +E LL+ + + L +IF LE+ GILA+ + + +
Sbjct: 62 YILVVAGTVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTE 121
Query: 125 LNLFINNNV-KAYRDDID--LQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRER 181
L + + + K Y + + +D Q+ + CCG+ DW + + S+E
Sbjct: 122 LKENLKDTMTKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIR------SQEA 175
Query: 182 CG--VPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLI 239
G VP SCC A L Q + + V G GC+ + E ++Q++L
Sbjct: 176 GGRVVPDSCCKTVVA---LCGQRDHASNIYKVEG-----------GCITKLETFIQEHLR 221
Query: 240 VVAGVFMGIALLQIFGI----CLAQNL 262
V+ V +GIA +Q+FG+ CL ++L
Sbjct: 222 VIGAVGIGIACVQVFGMIFTCCLYRSL 248
>gi|87159822 CD151 antigen [Homo sapiens]
Length = 253
Score = 105 bits (261), Expect = 7e-23
Identities = 79/267 (29%), Positives = 125/267 (46%), Gaps = 34/267 (12%)
Query: 8 FQEPEVGC---CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPV 64
F E + C C KY LF +N FW+ G +A+G+W K IS L L
Sbjct: 4 FNEKKTTCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKS--DYISLLASGTYLATA 61
Query: 65 WLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQ 124
++ VV G V+ V G GC +E LL+ + + L +IF LE+ GILA+ + + +
Sbjct: 62 YILVVAGTVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTE 121
Query: 125 LNLFINNNV-KAYRDDID--LQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRER 181
L + + + K Y + + +D Q+ + CCG+ DW + + S+E
Sbjct: 122 LKENLKDTMTKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIR------SQEA 175
Query: 182 CG--VPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLI 239
G VP SCC A L Q + + V G GC+ + E ++Q++L
Sbjct: 176 GGRVVPDSCCKTVVA---LCGQRDHASNIYKVEG-----------GCITKLETFIQEHLR 221
Query: 240 VVAGVFMGIALLQIFGI----CLAQNL 262
V+ V +GIA +Q+FG+ CL ++L
Sbjct: 222 VIGAVGIGIACVQVFGMIFTCCLYRSL 248
>gi|21237751 CD151 antigen [Homo sapiens]
Length = 253
Score = 105 bits (261), Expect = 7e-23
Identities = 79/267 (29%), Positives = 125/267 (46%), Gaps = 34/267 (12%)
Query: 8 FQEPEVGC---CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPV 64
F E + C C KY LF +N FW+ G +A+G+W K IS L L
Sbjct: 4 FNEKKTTCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKS--DYISLLASGTYLATA 61
Query: 65 WLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQ 124
++ VV G V+ V G GC +E LL+ + + L +IF LE+ GILA+ + + +
Sbjct: 62 YILVVAGTVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTE 121
Query: 125 LNLFINNNV-KAYRDDID--LQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRER 181
L + + + K Y + + +D Q+ + CCG+ DW + + S+E
Sbjct: 122 LKENLKDTMTKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIR------SQEA 175
Query: 182 CG--VPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLI 239
G VP SCC A L Q + + V G GC+ + E ++Q++L
Sbjct: 176 GGRVVPDSCCKTVVA---LCGQRDHASNIYKVEG-----------GCITKLETFIQEHLR 221
Query: 240 VVAGVFMGIALLQIFGI----CLAQNL 262
V+ V +GIA +Q+FG+ CL ++L
Sbjct: 222 VIGAVGIGIACVQVFGMIFTCCLYRSL 248
>gi|21237748 CD151 antigen [Homo sapiens]
Length = 253
Score = 105 bits (261), Expect = 7e-23
Identities = 79/267 (29%), Positives = 125/267 (46%), Gaps = 34/267 (12%)
Query: 8 FQEPEVGC---CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPV 64
F E + C C KY LF +N FW+ G +A+G+W K IS L L
Sbjct: 4 FNEKKTTCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKS--DYISLLASGTYLATA 61
Query: 65 WLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQ 124
++ VV G V+ V G GC +E LL+ + + L +IF LE+ GILA+ + + +
Sbjct: 62 YILVVAGTVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTE 121
Query: 125 LNLFINNNV-KAYRDDID--LQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRER 181
L + + + K Y + + +D Q+ + CCG+ DW + + S+E
Sbjct: 122 LKENLKDTMTKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIR------SQEA 175
Query: 182 CG--VPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLI 239
G VP SCC A L Q + + V G GC+ + E ++Q++L
Sbjct: 176 GGRVVPDSCCKTVVA---LCGQRDHASNIYKVEG-----------GCITKLETFIQEHLR 221
Query: 240 VVAGVFMGIALLQIFGI----CLAQNL 262
V+ V +GIA +Q+FG+ CL ++L
Sbjct: 222 VIGAVGIGIACVQVFGMIFTCCLYRSL 248
>gi|68800005 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 104 bits (260), Expect = 1e-22
Identities = 74/257 (28%), Positives = 113/257 (43%), Gaps = 34/257 (13%)
Query: 18 KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVL 77
KY +F FN++FW+ G L +G+W +G + +S+ L L ++ G + +
Sbjct: 10 KYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSS--SFPSLSAANLLIITGAFVMAI 67
Query: 78 GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAY- 136
GF GC+GA++EN LL F + L L+F LE IL F + D I + + Y
Sbjct: 68 GFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYG 127
Query: 137 -RDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAE 195
+ ++ L N Q + CCG DW +Y N +R VP SCC+
Sbjct: 128 TQGNVGLTNAWSIIQTDFRCCGVSNYTDW-FEVY------NATR----VPDSCCLE---- 172
Query: 196 DVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFG 255
+ CG L G C + WLQ+NL+ V + AL+QI G
Sbjct: 173 --FSESCG-----------LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILG 219
Query: 256 ICLAQNLVSDIKAVKAN 272
+ A + + VKA+
Sbjct: 220 LTFAMTMYCQV--VKAD 234
>gi|4507543 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 104 bits (260), Expect = 1e-22
Identities = 74/257 (28%), Positives = 113/257 (43%), Gaps = 34/257 (13%)
Query: 18 KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVL 77
KY +F FN++FW+ G L +G+W +G + +S+ L L ++ G + +
Sbjct: 10 KYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSS--SFPSLSAANLLIITGAFVMAI 67
Query: 78 GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAY- 136
GF GC+GA++EN LL F + L L+F LE IL F + D I + + Y
Sbjct: 68 GFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYG 127
Query: 137 -RDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAE 195
+ ++ L N Q + CCG DW +Y N +R VP SCC+
Sbjct: 128 TQGNVGLTNAWSIIQTDFRCCGVSNYTDW-FEVY------NATR----VPDSCCLE---- 172
Query: 196 DVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFG 255
+ CG L G C + WLQ+NL+ V + AL+QI G
Sbjct: 173 --FSESCG-----------LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILG 219
Query: 256 ICLAQNLVSDIKAVKAN 272
+ A + + VKA+
Sbjct: 220 LTFAMTMYCQV--VKAD 234
>gi|68800018 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 104 bits (260), Expect = 1e-22
Identities = 74/257 (28%), Positives = 113/257 (43%), Gaps = 34/257 (13%)
Query: 18 KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVL 77
KY +F FN++FW+ G L +G+W +G + +S+ L L ++ G + +
Sbjct: 10 KYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSS--SFPSLSAANLLIITGAFVMAI 67
Query: 78 GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAY- 136
GF GC+GA++EN LL F + L L+F LE IL F + D I + + Y
Sbjct: 68 GFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYG 127
Query: 137 -RDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAE 195
+ ++ L N Q + CCG DW +Y N +R VP SCC+
Sbjct: 128 TQGNVGLTNAWSIIQTDFRCCGVSNYTDW-FEVY------NATR----VPDSCCLE---- 172
Query: 196 DVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFG 255
+ CG L G C + WLQ+NL+ V + AL+QI G
Sbjct: 173 --FSESCG-----------LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILG 219
Query: 256 ICLAQNLVSDIKAVKAN 272
+ A + + VKA+
Sbjct: 220 LTFAMTMYCQV--VKAD 234
>gi|68800024 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 104 bits (260), Expect = 1e-22
Identities = 74/257 (28%), Positives = 113/257 (43%), Gaps = 34/257 (13%)
Query: 18 KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVL 77
KY +F FN++FW+ G L +G+W +G + +S+ L L ++ G + +
Sbjct: 10 KYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSS--SFPSLSAANLLIITGAFVMAI 67
Query: 78 GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAY- 136
GF GC+GA++EN LL F + L L+F LE IL F + D I + + Y
Sbjct: 68 GFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYG 127
Query: 137 -RDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAE 195
+ ++ L N Q + CCG DW +Y N +R VP SCC+
Sbjct: 128 TQGNVGLTNAWSIIQTDFRCCGVSNYTDW-FEVY------NATR----VPDSCCLE---- 172
Query: 196 DVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFG 255
+ CG L G C + WLQ+NL+ V + AL+QI G
Sbjct: 173 --FSESCG-----------LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILG 219
Query: 256 ICLAQNLVSDIKAVKAN 272
+ A + + VKA+
Sbjct: 220 LTFAMTMYCQV--VKAD 234
>gi|68800011 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 104 bits (260), Expect = 1e-22
Identities = 74/257 (28%), Positives = 113/257 (43%), Gaps = 34/257 (13%)
Query: 18 KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVL 77
KY +F FN++FW+ G L +G+W +G + +S+ L L ++ G + +
Sbjct: 10 KYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSS--SFPSLSAANLLIITGAFVMAI 67
Query: 78 GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAY- 136
GF GC+GA++EN LL F + L L+F LE IL F + D I + + Y
Sbjct: 68 GFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYG 127
Query: 137 -RDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAE 195
+ ++ L N Q + CCG DW +Y N +R VP SCC+
Sbjct: 128 TQGNVGLTNAWSIIQTDFRCCGVSNYTDW-FEVY------NATR----VPDSCCLE---- 172
Query: 196 DVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFG 255
+ CG L G C + WLQ+NL+ V + AL+QI G
Sbjct: 173 --FSESCG-----------LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILG 219
Query: 256 ICLAQNLVSDIKAVKAN 272
+ A + + VKA+
Sbjct: 220 LTFAMTMYCQV--VKAD 234
>gi|68799997 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 104 bits (260), Expect = 1e-22
Identities = 74/257 (28%), Positives = 113/257 (43%), Gaps = 34/257 (13%)
Query: 18 KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVL 77
KY +F FN++FW+ G L +G+W +G + +S+ L L ++ G + +
Sbjct: 10 KYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSS--SFPSLSAANLLIITGAFVMAI 67
Query: 78 GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAY- 136
GF GC+GA++EN LL F + L L+F LE IL F + D I + + Y
Sbjct: 68 GFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYG 127
Query: 137 -RDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAE 195
+ ++ L N Q + CCG DW +Y N +R VP SCC+
Sbjct: 128 TQGNVGLTNAWSIIQTDFRCCGVSNYTDW-FEVY------NATR----VPDSCCLE---- 172
Query: 196 DVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFG 255
+ CG L G C + WLQ+NL+ V + AL+QI G
Sbjct: 173 --FSESCG-----------LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILG 219
Query: 256 ICLAQNLVSDIKAVKAN 272
+ A + + VKA+
Sbjct: 220 LTFAMTMYCQV--VKAD 234
>gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens]
Length = 245
Score = 101 bits (251), Expect = 1e-21
Identities = 71/260 (27%), Positives = 114/260 (43%), Gaps = 31/260 (11%)
Query: 1 MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG 60
M + Q V C K L + +FW+ G + LA+G+W K L N +L +
Sbjct: 1 MASPSRRLQTKPVITCFKSVLLIYTFIFWITGVILLAVGIWG---KVSLENYFSLLNEKA 57
Query: 61 LDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDW 120
+ ++ + G V+ +LG GC R + ++LK +++FL L+F +EL I+ FVF+
Sbjct: 58 TNVPFVLIATGTVIILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHE 117
Query: 121 IRDQLNLFINNNVKAYRDDIDLQ-NLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSR 179
I++ +K Y D + + +D Q CCG DW TD N
Sbjct: 118 IKNSFKNNYEKALKQYNSTGDYRSHAVDKIQNTLHCCGVTDYRDW--------TDTNYYS 169
Query: 180 ERCGVPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLI 239
E+ G P SCC ED + ++ +GC + ++ +
Sbjct: 170 EK-GFPKSCC---KLEDCTPQR---------------DADKVNNEGCFIKVMTIIESEMG 210
Query: 240 VVAGVFMGIALLQIFGICLA 259
VVAG+ G+A Q+ GI LA
Sbjct: 211 VVAGISFGVACFQLIGIFLA 230
>gi|72534746 tetraspanin 18 isoform 1 [Homo sapiens]
Length = 267
Score = 100 bits (249), Expect = 2e-21
Identities = 63/185 (34%), Positives = 92/185 (49%), Gaps = 18/185 (9%)
Query: 16 CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMS 75
C KY +F FN ++ GA LAIG+W + I A L L ++ + +GG++
Sbjct: 8 CMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLL-LTGAYILLAMGGLLF 66
Query: 76 VLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKA 135
+LGF GC GA+REN LL FF +F+ +IF EL+ ILAF+F++ + + F K
Sbjct: 67 LLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTRE--FFTKELTKH 124
Query: 136 YRDDIDLQNLIDFAQEYWS-------CCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSC 188
Y+ + D D W+ CCG GP D+ F L+ VP +C
Sbjct: 125 YQGNND----TDVFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEE----VPEAC 176
Query: 189 CVRDP 193
C R+P
Sbjct: 177 CRREP 181
>gi|67782354 CD82 antigen isoform 2 [Homo sapiens]
Length = 242
Score = 98.6 bits (244), Expect = 7e-21
Identities = 68/254 (26%), Positives = 122/254 (48%), Gaps = 35/254 (13%)
Query: 18 KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVL 77
KYFLF FN++F++LGA+ L G+W +K ++ + ++F+ VG V ++
Sbjct: 10 KYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFIGVGAVTMLM 69
Query: 78 GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAYR 137
GF GCIGA+ E LL +G GI+ + +D+ + R
Sbjct: 70 GFLGCIGAVNEVRCLLGLLKQEMG---------GIVTELIRDY-------------NSSR 107
Query: 138 DDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAEDV 197
+D LQ+ D+ Q CCG +W N +R P SC V+ ++
Sbjct: 108 ED-SLQDAWDYVQAQVKCCGWVSFYNWTDNAELM------NRPEVTYPCSCEVKGEEDNS 160
Query: 198 LNTQCGYDVRL--KLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFG 255
L+ + G+ + G + ++ +GC+ + + WLQ+NL ++ GV +G+A++++ G
Sbjct: 161 LSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAIIELLG 220
Query: 256 ----ICLAQNLVSD 265
ICL +++ S+
Sbjct: 221 MVLSICLCRHVHSE 234
>gi|122937466 tetraspanin 11 [Homo sapiens]
Length = 253
Score = 98.6 bits (244), Expect = 7e-21
Identities = 77/256 (30%), Positives = 117/256 (45%), Gaps = 35/256 (13%)
Query: 18 KYFLFGFNIVFWVLGALFLAIGLWAWGEK-GVLSNISALTDLGGLDPVWLFVVVGGVMSV 76
KY LF FN FWV GA LA+G+W EK G LS +++ T ++ + G ++ V
Sbjct: 17 KYLLFVFNFFFWVGGAAVLAVGIWTLVEKSGYLSVLASSTFAAS---AYILIFAGVLVMV 73
Query: 77 LGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVK-- 134
GF G L E L + L +IF +EL G+LA V+ + D+L +N +
Sbjct: 74 TGFLGFGAILWERKGCLSTYFCLLLVIFLVELVAGVLAHVYYQRLSDELKQHLNRTLAEN 133
Query: 135 -AYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDP 193
+ +D Q+ + CCG+ DW + Y L E VP SCC
Sbjct: 134 YGQPGATQITASVDRLQQDFKCCGSNSSADWQHSTYI----LLREAEGRQVPDSCC---- 185
Query: 194 AEDVLNTQCG---YDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIAL 250
+ +CG + + V G GC+ + E++L D+L+++ V +G+A
Sbjct: 186 --KTVVVRCGQRAHPSNIYKVEG-----------GCLTKLEQFLADHLLLMGAVGIGVAC 232
Query: 251 LQIFGI----CLAQNL 262
LQI G+ CL Q L
Sbjct: 233 LQICGMVLTCCLHQRL 248
>gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens]
Length = 237
Score = 97.8 bits (242), Expect = 1e-20
Identities = 74/264 (28%), Positives = 113/264 (42%), Gaps = 43/264 (16%)
Query: 13 VGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLD--PVWLFVVV 70
V C KY +F FN +FW+ G L LA+ +W + I D+G V + + V
Sbjct: 4 VSACIKYSMFTFNFLFWLCGILILALAIWVRVSNDSQA-IFGSEDVGSSSYVAVDILIAV 62
Query: 71 GGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFIN 130
G ++ +LGF GC GA++E+ +L F + L LI L++ATGIL VFK +N +
Sbjct: 63 GAIIMILGFLGCCGAIKESRCMLLLFFIGLLLILLLQVATGILGAVFKSKSDRIVNETLY 122
Query: 131 NNVKAY----RDDIDLQNLIDFAQEYWSCCG-ARGPNDWNLNIYFN---CTDLNPSRERC 182
N K + Q I QE + CCG G DW N C L+ R
Sbjct: 123 ENTKLLSATGESEKQFQEAIIVFQEEFKCCGLVNGAADWGNNFQHYPELCACLDKQR--- 179
Query: 183 GVPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVA 242
P + Q ++ + C+ + +L NLI+V
Sbjct: 180 ----------PCQSYNGKQ-------------------VYKETCISFIKDFLAKNLIIVI 210
Query: 243 GVFMGIALLQIFGICLAQNLVSDI 266
G+ G+A+++I G+ + L I
Sbjct: 211 GISFGLAVIEILGLVFSMVLYCQI 234
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.144 0.487
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,761,664
Number of Sequences: 37866
Number of extensions: 615650
Number of successful extensions: 2485
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 2336
Number of HSP's gapped (non-prelim): 79
length of query: 332
length of database: 18,247,518
effective HSP length: 103
effective length of query: 229
effective length of database: 14,347,320
effective search space: 3285536280
effective search space used: 3285536280
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.