Search of human proteins with 54859505

Search of human proteins with 54859505

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|54859505 transmembrane 4 superfamily member 17 isoform c
[Homo sapiens]
         (266 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|54859505 transmembrane 4 superfamily member 17 isoform c [Hom...   561   e-160
gi|54859560 transmembrane 4 superfamily member 17 isoform a [Hom...   553   e-158
gi|50511934 transmembrane 4 superfamily member 17 isoform b [Hom...   542   e-154
gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens]       442   e-124
gi|190194420 tetraspanin 14 isoform 1 [Homo sapiens]                  316   2e-86
gi|30425534 tetraspanin 33 [Homo sapiens]                             225   4e-59
gi|6912530 transmembrane 4 superfamily member 15 [Homo sapiens]       163   1e-40
gi|190341022 tetraspanin 14 isoform 2 [Homo sapiens]                  144   1e-34
gi|119120834 tetraspanin 10 [Homo sapiens]                            140   9e-34
gi|4504813 CD82 antigen isoform 1 [Homo sapiens]                      113   2e-25
gi|21265104 tetraspanin 7 [Homo sapiens]                              112   3e-25
gi|4502679 CD63 antigen isoform A [Homo sapiens]                      108   4e-24
gi|5729941 tetraspanin 9 [Homo sapiens]                               106   2e-23
gi|42476204 tetraspanin 18 isoform 2 [Homo sapiens]                   105   3e-23
gi|91199546 CD63 antigen isoform B [Homo sapiens]                     105   3e-23
gi|87159824 CD151 antigen [Homo sapiens]                              105   4e-23
gi|87159822 CD151 antigen [Homo sapiens]                              105   4e-23
gi|21237751 CD151 antigen [Homo sapiens]                              105   4e-23
gi|21237748 CD151 antigen [Homo sapiens]                              105   4e-23
gi|68800005 tetraspanin 4 isoform a [Homo sapiens]                    103   1e-22
gi|4507543 tetraspanin 4 isoform a [Homo sapiens]                     103   1e-22
gi|68800018 tetraspanin 4 isoform a [Homo sapiens]                    103   1e-22
gi|68800024 tetraspanin 4 isoform a [Homo sapiens]                    103   1e-22
gi|68800011 tetraspanin 4 isoform a [Homo sapiens]                    103   1e-22
gi|68799997 tetraspanin 4 isoform a [Homo sapiens]                    103   1e-22
gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens]        101   6e-22
gi|72534746 tetraspanin 18 isoform 1 [Homo sapiens]                   100   1e-21
gi|122937466 tetraspanin 11 [Homo sapiens]                            100   2e-21
gi|67782354 CD82 antigen isoform 2 [Homo sapiens]                      97   1e-20
gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens]         97   1e-20

>gi|54859505 transmembrane 4 superfamily member 17 isoform c [Homo
           sapiens]
          Length = 266

 Score =  561 bits (1446), Expect = e-160
 Identities = 266/266 (100%), Positives = 266/266 (100%)

Query: 1   MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG 60
           MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG
Sbjct: 1   MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG 60

Query: 61  LDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDW 120
           LDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDW
Sbjct: 61  LDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDW 120

Query: 121 IRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRE 180
           IRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRE
Sbjct: 121 IRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRE 180

Query: 181 RCGVPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIV 240
           RCGVPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIV
Sbjct: 181 RCGVPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIV 240

Query: 241 VAGVFMGIALLQIFGICLAQNLEQME 266
           VAGVFMGIALLQIFGICLAQNLEQME
Sbjct: 241 VAGVFMGIALLQIFGICLAQNLEQME 266


>gi|54859560 transmembrane 4 superfamily member 17 isoform a [Homo
           sapiens]
          Length = 332

 Score =  553 bits (1426), Expect = e-158
 Identities = 262/262 (100%), Positives = 262/262 (100%)

Query: 1   MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG 60
           MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG
Sbjct: 1   MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG 60

Query: 61  LDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDW 120
           LDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDW
Sbjct: 61  LDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDW 120

Query: 121 IRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRE 180
           IRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRE
Sbjct: 121 IRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRE 180

Query: 181 RCGVPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIV 240
           RCGVPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIV
Sbjct: 181 RCGVPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIV 240

Query: 241 VAGVFMGIALLQIFGICLAQNL 262
           VAGVFMGIALLQIFGICLAQNL
Sbjct: 241 VAGVFMGIALLQIFGICLAQNL 262


>gi|50511934 transmembrane 4 superfamily member 17 isoform b [Homo
           sapiens]
          Length = 329

 Score =  542 bits (1397), Expect = e-154
 Identities = 259/262 (98%), Positives = 259/262 (98%), Gaps = 3/262 (1%)

Query: 1   MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG 60
           MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG
Sbjct: 1   MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG 60

Query: 61  LDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDW 120
           LDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDW
Sbjct: 61  LDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDW 120

Query: 121 IRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRE 180
           IRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRE
Sbjct: 121 IRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRE 180

Query: 181 RCGVPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIV 240
           RCGVPFSCCVRDPAEDVLNTQCGYDVRLKL   ELEQQGFIHTKGCVGQFEKWLQDNLIV
Sbjct: 181 RCGVPFSCCVRDPAEDVLNTQCGYDVRLKL---ELEQQGFIHTKGCVGQFEKWLQDNLIV 237

Query: 241 VAGVFMGIALLQIFGICLAQNL 262
           VAGVFMGIALLQIFGICLAQNL
Sbjct: 238 VAGVFMGIALLQIFGICLAQNL 259


>gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens]
          Length = 268

 Score =  442 bits (1138), Expect = e-124
 Identities = 205/262 (78%), Positives = 228/262 (87%), Gaps = 5/262 (1%)

Query: 1   MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG 60
           M GKH  ++ PEV CC KYF+FGFN++FW LG  FL IGLWAW EKGVLSNIS++TDLGG
Sbjct: 1   MSGKH--YKGPEVSCCIKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSNISSITDLGG 58

Query: 61  LDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDW 120
            DPVWLF+VVGGVM +LGFAGCIGALRENTFLLKFFSVFLG+IFFLEL  G+LAFVFKDW
Sbjct: 59  FDPVWLFLVVGGVMFILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVFKDW 118

Query: 121 IRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRE 180
           I+DQL  FINNN++AYRDDIDLQNLIDF QEYW CCGA G +DWNLNIYFNCTD N SRE
Sbjct: 119 IKDQLYFFINNNIRAYRDDIDLQNLIDFTQEYWQCCGAFGADDWNLNIYFNCTDSNASRE 178

Query: 181 RCGVPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIV 240
           RCGVPFSCC +DPAEDV+NTQCGYD R K    E++QQ  I+TKGCV QFEKWLQDNL +
Sbjct: 179 RCGVPFSCCTKDPAEDVINTQCGYDARQK---PEVDQQIVIYTKGCVPQFEKWLQDNLTI 235

Query: 241 VAGVFMGIALLQIFGICLAQNL 262
           VAG+F+GIALLQIFGICLAQNL
Sbjct: 236 VAGIFIGIALLQIFGICLAQNL 257


>gi|190194420 tetraspanin 14 isoform 1 [Homo sapiens]
          Length = 270

 Score =  316 bits (809), Expect = 2e-86
 Identities = 147/258 (56%), Positives = 191/258 (74%), Gaps = 3/258 (1%)

Query: 5   HQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPV 64
           +  +   +V C  KY LF +NI+FW+ G +FL +GLWAW EKGVLS+++ +T + G+DPV
Sbjct: 3   YYRYSNAKVSCWYKYLLFSYNIIFWLAGVVFLGVGLWAWSEKGVLSDLTKVTRMHGIDPV 62

Query: 65  WLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQ 124
            L ++VG VM  LGFAGC+GALREN  LL FF   + LIFFLELA  +LAF+F+DW+RD+
Sbjct: 63  VLVLMVGVVMFTLGFAGCVGALRENICLLNFFCGTIVLIFFLELAVAVLAFLFQDWVRDR 122

Query: 125 LNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGV 184
              F  +N+K+YRDDIDLQNLID  Q+   CCGA GP DW+LN+YFNC+  + SRE+CGV
Sbjct: 123 FREFFESNIKSYRDDIDLQNLIDSLQKANQCCGAYGPEDWDLNVYFNCSGASYSREKCGV 182

Query: 185 PFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGV 244
           PFSCCV DPA+ V+NTQCGYDVR++L   + +    I TKGC+   E WL  N+ +VAGV
Sbjct: 183 PFSCCVPDPAQKVVNTQCGYDVRIQL---KSKWDESIFTKGCIQALESWLPRNIYIVAGV 239

Query: 245 FMGIALLQIFGICLAQNL 262
           F+ I+LLQIFGI LA+ L
Sbjct: 240 FIAISLLQIFGIFLARTL 257


>gi|30425534 tetraspanin 33 [Homo sapiens]
          Length = 283

 Score =  225 bits (573), Expect = 4e-59
 Identities = 112/245 (45%), Positives = 160/245 (65%), Gaps = 7/245 (2%)

Query: 18  KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVL 77
           KY LF FN++FWV+  + +A+G++A   K   + ++ L     +DP  L +VVG +M +L
Sbjct: 23  KYLLFFFNMLFWVISMVMVAVGVYARLMKHAEAALACLA----VDPAILLIVVGVLMFLL 78

Query: 78  GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAYR 137
            F GCIG+LREN  LL+ FS+ L  +F L+LA GIL FVF D  R +++  INN +  YR
Sbjct: 79  TFCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHYR 138

Query: 138 DDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAEDV 197
           DD+DLQNLIDF Q+ +SCCG     DW+ N+YFNC++ NPSRERC VP+SCC+  P + V
Sbjct: 139 DDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQAV 198

Query: 198 LNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFGIC 257
           +NT CG  ++       LE    I+T GC+ +   W+  NL ++ GV +G+A+ Q+ GI 
Sbjct: 199 INTMCGQGMQ---AFDYLEASKVIYTNGCIDKLVNWIHSNLFLLGGVALGLAIPQLVGIL 255

Query: 258 LAQNL 262
           L+Q L
Sbjct: 256 LSQIL 260


>gi|6912530 transmembrane 4 superfamily member 15 [Homo sapiens]
          Length = 294

 Score =  163 bits (413), Expect = 1e-40
 Identities = 82/241 (34%), Positives = 136/241 (56%), Gaps = 10/241 (4%)

Query: 18  KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVL 77
           K+ L  ++ VFW++GAL L++G++A  E+     + +      L P  + +++G VM ++
Sbjct: 21  KFSLIIYSTVFWLIGALVLSVGIYAEVERQKYKTLESAF----LAPAIILILLGVVMFMV 76

Query: 78  GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAYR 137
            F G + +LR+N +LL+ F   LG+   +EL  G++A  F++   D LN  I   ++ Y 
Sbjct: 77  SFIGVLASLRDNLYLLQAFMYILGICLIMELIGGVVALTFRNQTIDFLNDNIRRGIENYY 136

Query: 138 DDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAEDV 197
           DD+D +N++DF Q+ + CCG     DW+ N Y +C+   P    CGVP++CC+R+  E V
Sbjct: 137 DDLDFKNIMDFVQKKFKCCGGEDYRDWSKNQYHDCS--APGPLACGVPYTCCIRNTTE-V 193

Query: 198 LNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFGIC 257
           +NT CGY     + +     Q  I+ +GC      W  DN  ++AG+ +GI L Q  G+ 
Sbjct: 194 VNTMCGYKT---IDKERFSVQDVIYVRGCTNAVIIWFMDNYTIMAGILLGILLPQFLGVL 250

Query: 258 L 258
           L
Sbjct: 251 L 251


>gi|190341022 tetraspanin 14 isoform 2 [Homo sapiens]
          Length = 147

 Score =  144 bits (362), Expect = 1e-34
 Identities = 66/112 (58%), Positives = 85/112 (75%), Gaps = 4/112 (3%)

Query: 152 YWS-CCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAEDVLNTQCGYDVRLKL 210
           +W+ CCGA GP DW+LN+YFNC+  + SRE+CGVPFSCCV DPA+ V+NTQCGYDVR++L
Sbjct: 26  FWNQCCGAYGPEDWDLNVYFNCSGASYSREKCGVPFSCCVPDPAQKVVNTQCGYDVRIQL 85

Query: 211 VRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFGICLAQNL 262
              + +    I TKGC+   E WL  N+ +VAGVF+ I+LLQIFGI LA+ L
Sbjct: 86  ---KSKWDESIFTKGCIQALESWLPRNIYIVAGVFIAISLLQIFGIFLARTL 134



 Score = 30.4 bits (67), Expect = 1.7
 Identities = 10/25 (40%), Positives = 15/25 (60%)

Query: 5  HQHFQEPEVGCCGKYFLFGFNIVFW 29
          +  +   +V C  KY LF +NI+FW
Sbjct: 3  YYRYSNAKVSCWYKYLLFSYNIIFW 27


>gi|119120834 tetraspanin 10 [Homo sapiens]
          Length = 355

 Score =  140 bits (354), Expect = 9e-34
 Identities = 95/252 (37%), Positives = 129/252 (51%), Gaps = 16/252 (6%)

Query: 16  CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG---LDPVWLFVVVGG 72
           C KY +F  N  F +LG L LAIGLW    KG L +     DLGG    DP+    + G 
Sbjct: 75  CVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGS-----DLGGPLPADPMLGLALGGL 129

Query: 73  VMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNN 132
           V+S +  AG +GAL ENT LL+ FS  +     LE   G L       ++D L   +   
Sbjct: 130 VVSAVSLAGYLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVA 189

Query: 133 VKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRD 192
           +  Y+DD DL+ L+D  Q    CCGA    DW  N+YFNC+  +P  + C +P SCC+ D
Sbjct: 190 IAHYQDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCS--SPGVQACSLPASCCI-D 246

Query: 193 PAED--VLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIAL 250
           P ED   +N QCG+ V L+L       Q  ++ +GC     +WL+ NL    G  + + L
Sbjct: 247 PREDGASVNDQCGFGV-LRLDAD--AAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVL 303

Query: 251 LQIFGICLAQNL 262
           LQ   + LA  L
Sbjct: 304 LQGAELLLAARL 315


>gi|4504813 CD82 antigen isoform 1 [Homo sapiens]
          Length = 267

 Score =  113 bits (282), Expect = 2e-25
 Identities = 68/247 (27%), Positives = 125/247 (50%), Gaps = 12/247 (4%)

Query: 18  KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVL 77
           KYFLF FN++F++LGA+ L  G+W   +K    ++   +        ++F+ VG V  ++
Sbjct: 10  KYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFIGVGAVTMLM 69

Query: 78  GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAY- 136
           GF GCIGA+ E   LL  +  FL LI   ++  G L +     ++ ++   +   ++ Y 
Sbjct: 70  GFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGIVTELIRDYN 129

Query: 137 --RDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPA 194
             R+D  LQ+  D+ Q    CCG     +W  N          +R     P SC V+   
Sbjct: 130 SSRED-SLQDAWDYVQAQVKCCGWVSFYNWTDNAEL------MNRPEVTYPCSCEVKGEE 182

Query: 195 EDVLNTQCGY--DVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQ 252
           ++ L+ + G+      +   G   +   ++ +GC+ + + WLQ+NL ++ GV +G+A+++
Sbjct: 183 DNSLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAIIE 242

Query: 253 IFGICLA 259
           + G+ L+
Sbjct: 243 LLGMVLS 249


>gi|21265104 tetraspanin 7 [Homo sapiens]
          Length = 249

 Score =  112 bits (281), Expect = 3e-25
 Identities = 67/244 (27%), Positives = 115/244 (47%), Gaps = 23/244 (9%)

Query: 16  CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMS 75
           C K  L  ++ VFW+ G + LA+G+W    K  L    +L      +  ++ +  G  + 
Sbjct: 14  CLKTLLIIYSFVFWITGVILLAVGVWG---KLTLGTYISLIAENSTNAPYVLIGTGTTIV 70

Query: 76  VLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKA 135
           V G  GC    R + ++LK +++FL L+F  EL  GI  FVF+  I+D       + ++ 
Sbjct: 71  VFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHEIKDTFLRTYTDAMQT 130

Query: 136 YRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAE 195
           Y  + +    +D  Q   SCCG +   +W+ + YF            G+P SCC+    E
Sbjct: 131 YNGNDERSRAVDHVQRSLSCCGVQNYTNWSTSPYF---------LEHGIPPSCCMN---E 178

Query: 196 DVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFG 255
              N Q  +++ +   +        ++ KGC      +++ N+ ++AGV  GIA  Q+ G
Sbjct: 179 TDCNPQDLHNLTVAATK--------VNQKGCYDLVTSFMETNMGIIAGVAFGIAFSQLIG 230

Query: 256 ICLA 259
           + LA
Sbjct: 231 MLLA 234


>gi|4502679 CD63 antigen isoform A [Homo sapiens]
          Length = 238

 Score =  108 bits (271), Expect = 4e-24
 Identities = 74/246 (30%), Positives = 117/246 (47%), Gaps = 32/246 (13%)

Query: 16  CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSN--ISALTDLGGLDPVWLFVVVGGV 73
           C K+ L+   + F       +A+G+   G + VLS   I   T  G L PV + + VG  
Sbjct: 9   CVKFLLYVLLLAFCACAVGLIAVGV---GAQLVLSQTIIQGATP-GSLLPV-VIIAVGVF 63

Query: 74  MSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNV 133
           + ++ F GC GA +EN  L+  F++FL LI  +E+A  I  +VF+D +  + N      +
Sbjct: 64  LFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQM 123

Query: 134 KAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDP 193
           + Y  +    +++D  Q  + CCGA    DW         +  PS  +  VP SCC+   
Sbjct: 124 ENYPKNNHTASILDRMQADFKCCGAANYTDW---------EKIPSMSKNRVPDSCCIN-- 172

Query: 194 AEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQI 253
               +   CG +   K           IH +GCV +   WL+ N++VVA   +GIA +++
Sbjct: 173 ----VTVGCGINFNEKA----------IHKEGCVEKIGGWLRKNVLVVAAAALGIAFVEV 218

Query: 254 FGICLA 259
            GI  A
Sbjct: 219 LGIVFA 224


>gi|5729941 tetraspanin 9 [Homo sapiens]
          Length = 239

 Score =  106 bits (264), Expect = 2e-23
 Identities = 71/252 (28%), Positives = 109/252 (43%), Gaps = 32/252 (12%)

Query: 15  CCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVM 74
           CC KY +F FN++FW+ G   L +G+W    +G  +  S       L    L + +G ++
Sbjct: 7   CCLKYMMFLFNLIFWLCGCGLLGVGIWLSVSQGNFATFSP--SFPSLSAANLVIAIGTIV 64

Query: 75  SVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVK 134
            V GF GC+GA++EN  LL  F + L +I   EL   IL FV+ D + +     +   + 
Sbjct: 65  MVTGFLGCLGAIKENKCLLLSFFIVLLVILLAELILLILFFVYMDKVNENAKKDLKEGLL 124

Query: 135 AY--RDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRD 192
            Y   +++ L+N  +  Q    CCG     DW            P      VP  CC+ +
Sbjct: 125 LYHTENNVGLKNAWNIIQAEMRCCGVTDYTDW-----------YPVLGENTVPDRCCMEN 173

Query: 193 PAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQ 252
                 +  CG +    L R            GC  + + W  DN  V+  V M I ++Q
Sbjct: 174 ------SQGCGRNATTPLWR-----------TGCYEKVKMWFDDNKHVLGTVGMCILIMQ 216

Query: 253 IFGICLAQNLEQ 264
           I G+  +  L Q
Sbjct: 217 ILGMAFSMTLFQ 228


>gi|42476204 tetraspanin 18 isoform 2 [Homo sapiens]
          Length = 248

 Score =  105 bits (263), Expect = 3e-23
 Identities = 74/254 (29%), Positives = 117/254 (46%), Gaps = 25/254 (9%)

Query: 16  CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMS 75
           C KY +F FN   ++ GA  LAIG+W   +      I A   L  L   ++ + +GG++ 
Sbjct: 8   CMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLL-LTGAYILLAMGGLLF 66

Query: 76  VLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKA 135
           +LGF GC GA+REN  LL FF +F+ +IF  EL+  ILAF+F++ +  +   F     K 
Sbjct: 67  LLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTRE--FFTKELTKH 124

Query: 136 YRDDIDLQNLIDFAQEYWS-------CCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSC 188
           Y+ + D     D     W+       CCG  GP D+     F    L+       VP +C
Sbjct: 125 YQGNND----TDIFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEE----VPEAC 176

Query: 189 CVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGI 248
           C R+P       Q    V L      L +  F++ +GC        +  + +   + +G+
Sbjct: 177 CRREP-------QSRDGVLLSREECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGV 229

Query: 249 ALLQIFGICLAQNL 262
             +++F +  A  L
Sbjct: 230 LAIELFAMIFAMCL 243


>gi|91199546 CD63 antigen isoform B [Homo sapiens]
          Length = 236

 Score =  105 bits (263), Expect = 3e-23
 Identities = 74/251 (29%), Positives = 119/251 (47%), Gaps = 34/251 (13%)

Query: 16  CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSN--ISALTDLGGLDPVWLFVVVGGV 73
           C K+ L+   + F       +A+G+   G + VLS   I   T  G L PV + + VG  
Sbjct: 9   CVKFLLYVLLLAFCACAVGLIAVGV---GAQLVLSQTIIQGATP-GSLLPV-VIIAVGVF 63

Query: 74  MSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNV 133
           + ++ F GC GA +EN  L+  F++FL LI  +E+A  I  +VF+D +  + N      +
Sbjct: 64  LFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDKVMSEFNNNFRQQM 123

Query: 134 KAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDP 193
           + Y  +    +++D  Q  + CCGA    DW         +  PS  +  VP SCC+   
Sbjct: 124 ENYPKNNHTASILDRMQADFKCCGAANYTDW---------EKIPSMSKNRVPDSCCIN-- 172

Query: 194 AEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQ- 252
               +   CG +   K           IH +GCV +   WL+ N++VVA   +GIA +  
Sbjct: 173 ----VTVGCGINFNEKA----------IHKEGCVEKIGGWLRKNVLVVAAAALGIAFVLG 218

Query: 253 -IFGICLAQNL 262
            +F  CL +++
Sbjct: 219 IVFACCLVKSI 229


>gi|87159824 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  105 bits (262), Expect = 4e-23
 Identities = 79/268 (29%), Positives = 126/268 (47%), Gaps = 34/268 (12%)

Query: 8   FQEPEVGC---CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPV 64
           F E +  C   C KY LF +N  FW+ G   +A+G+W    K     IS L     L   
Sbjct: 4   FNEKKTTCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKS--DYISLLASGTYLATA 61

Query: 65  WLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQ 124
           ++ VV G V+ V G  GC    +E   LL+ + + L +IF LE+  GILA+ +   +  +
Sbjct: 62  YILVVAGTVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTE 121

Query: 125 LNLFINNNV-KAYRD--DIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRER 181
           L   + + + K Y       + + +D  Q+ + CCG+    DW  + +        S+E 
Sbjct: 122 LKENLKDTMTKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIR------SQEA 175

Query: 182 CG--VPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLI 239
            G  VP SCC    A   L  Q  +   +  V G           GC+ + E ++Q++L 
Sbjct: 176 GGRVVPDSCCKTVVA---LCGQRDHASNIYKVEG-----------GCITKLETFIQEHLR 221

Query: 240 VVAGVFMGIALLQIFGI----CLAQNLE 263
           V+  V +GIA +Q+FG+    CL ++L+
Sbjct: 222 VIGAVGIGIACVQVFGMIFTCCLYRSLK 249


>gi|87159822 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  105 bits (262), Expect = 4e-23
 Identities = 79/268 (29%), Positives = 126/268 (47%), Gaps = 34/268 (12%)

Query: 8   FQEPEVGC---CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPV 64
           F E +  C   C KY LF +N  FW+ G   +A+G+W    K     IS L     L   
Sbjct: 4   FNEKKTTCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKS--DYISLLASGTYLATA 61

Query: 65  WLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQ 124
           ++ VV G V+ V G  GC    +E   LL+ + + L +IF LE+  GILA+ +   +  +
Sbjct: 62  YILVVAGTVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTE 121

Query: 125 LNLFINNNV-KAYRD--DIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRER 181
           L   + + + K Y       + + +D  Q+ + CCG+    DW  + +        S+E 
Sbjct: 122 LKENLKDTMTKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIR------SQEA 175

Query: 182 CG--VPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLI 239
            G  VP SCC    A   L  Q  +   +  V G           GC+ + E ++Q++L 
Sbjct: 176 GGRVVPDSCCKTVVA---LCGQRDHASNIYKVEG-----------GCITKLETFIQEHLR 221

Query: 240 VVAGVFMGIALLQIFGI----CLAQNLE 263
           V+  V +GIA +Q+FG+    CL ++L+
Sbjct: 222 VIGAVGIGIACVQVFGMIFTCCLYRSLK 249


>gi|21237751 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  105 bits (262), Expect = 4e-23
 Identities = 79/268 (29%), Positives = 126/268 (47%), Gaps = 34/268 (12%)

Query: 8   FQEPEVGC---CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPV 64
           F E +  C   C KY LF +N  FW+ G   +A+G+W    K     IS L     L   
Sbjct: 4   FNEKKTTCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKS--DYISLLASGTYLATA 61

Query: 65  WLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQ 124
           ++ VV G V+ V G  GC    +E   LL+ + + L +IF LE+  GILA+ +   +  +
Sbjct: 62  YILVVAGTVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTE 121

Query: 125 LNLFINNNV-KAYRD--DIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRER 181
           L   + + + K Y       + + +D  Q+ + CCG+    DW  + +        S+E 
Sbjct: 122 LKENLKDTMTKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIR------SQEA 175

Query: 182 CG--VPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLI 239
            G  VP SCC    A   L  Q  +   +  V G           GC+ + E ++Q++L 
Sbjct: 176 GGRVVPDSCCKTVVA---LCGQRDHASNIYKVEG-----------GCITKLETFIQEHLR 221

Query: 240 VVAGVFMGIALLQIFGI----CLAQNLE 263
           V+  V +GIA +Q+FG+    CL ++L+
Sbjct: 222 VIGAVGIGIACVQVFGMIFTCCLYRSLK 249


>gi|21237748 CD151 antigen [Homo sapiens]
          Length = 253

 Score =  105 bits (262), Expect = 4e-23
 Identities = 79/268 (29%), Positives = 126/268 (47%), Gaps = 34/268 (12%)

Query: 8   FQEPEVGC---CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPV 64
           F E +  C   C KY LF +N  FW+ G   +A+G+W    K     IS L     L   
Sbjct: 4   FNEKKTTCGTVCLKYLLFTYNCCFWLAGLAVMAVGIWTLALKS--DYISLLASGTYLATA 61

Query: 65  WLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQ 124
           ++ VV G V+ V G  GC    +E   LL+ + + L +IF LE+  GILA+ +   +  +
Sbjct: 62  YILVVAGTVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTE 121

Query: 125 LNLFINNNV-KAYRD--DIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRER 181
           L   + + + K Y       + + +D  Q+ + CCG+    DW  + +        S+E 
Sbjct: 122 LKENLKDTMTKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDWRDSEWIR------SQEA 175

Query: 182 CG--VPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLI 239
            G  VP SCC    A   L  Q  +   +  V G           GC+ + E ++Q++L 
Sbjct: 176 GGRVVPDSCCKTVVA---LCGQRDHASNIYKVEG-----------GCITKLETFIQEHLR 221

Query: 240 VVAGVFMGIALLQIFGI----CLAQNLE 263
           V+  V +GIA +Q+FG+    CL ++L+
Sbjct: 222 VIGAVGIGIACVQVFGMIFTCCLYRSLK 249


>gi|68800005 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  103 bits (258), Expect = 1e-22
 Identities = 71/247 (28%), Positives = 108/247 (43%), Gaps = 32/247 (12%)

Query: 18  KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVL 77
           KY +F FN++FW+ G   L +G+W    +G  + +S+      L    L ++ G  +  +
Sbjct: 10  KYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSS--SFPSLSAANLLIITGAFVMAI 67

Query: 78  GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAY- 136
           GF GC+GA++EN  LL  F + L L+F LE    IL F + D I       +   +  Y 
Sbjct: 68  GFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYG 127

Query: 137 -RDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAE 195
            + ++ L N     Q  + CCG     DW   +Y      N +R    VP SCC+     
Sbjct: 128 TQGNVGLTNAWSIIQTDFRCCGVSNYTDW-FEVY------NATR----VPDSCCLE---- 172

Query: 196 DVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFG 255
              +  CG           L   G      C    + WLQ+NL+ V    +  AL+QI G
Sbjct: 173 --FSESCG-----------LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILG 219

Query: 256 ICLAQNL 262
           +  A  +
Sbjct: 220 LTFAMTM 226


>gi|4507543 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  103 bits (258), Expect = 1e-22
 Identities = 71/247 (28%), Positives = 108/247 (43%), Gaps = 32/247 (12%)

Query: 18  KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVL 77
           KY +F FN++FW+ G   L +G+W    +G  + +S+      L    L ++ G  +  +
Sbjct: 10  KYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSS--SFPSLSAANLLIITGAFVMAI 67

Query: 78  GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAY- 136
           GF GC+GA++EN  LL  F + L L+F LE    IL F + D I       +   +  Y 
Sbjct: 68  GFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYG 127

Query: 137 -RDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAE 195
            + ++ L N     Q  + CCG     DW   +Y      N +R    VP SCC+     
Sbjct: 128 TQGNVGLTNAWSIIQTDFRCCGVSNYTDW-FEVY------NATR----VPDSCCLE---- 172

Query: 196 DVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFG 255
              +  CG           L   G      C    + WLQ+NL+ V    +  AL+QI G
Sbjct: 173 --FSESCG-----------LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILG 219

Query: 256 ICLAQNL 262
           +  A  +
Sbjct: 220 LTFAMTM 226


>gi|68800018 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  103 bits (258), Expect = 1e-22
 Identities = 71/247 (28%), Positives = 108/247 (43%), Gaps = 32/247 (12%)

Query: 18  KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVL 77
           KY +F FN++FW+ G   L +G+W    +G  + +S+      L    L ++ G  +  +
Sbjct: 10  KYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSS--SFPSLSAANLLIITGAFVMAI 67

Query: 78  GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAY- 136
           GF GC+GA++EN  LL  F + L L+F LE    IL F + D I       +   +  Y 
Sbjct: 68  GFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYG 127

Query: 137 -RDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAE 195
            + ++ L N     Q  + CCG     DW   +Y      N +R    VP SCC+     
Sbjct: 128 TQGNVGLTNAWSIIQTDFRCCGVSNYTDW-FEVY------NATR----VPDSCCLE---- 172

Query: 196 DVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFG 255
              +  CG           L   G      C    + WLQ+NL+ V    +  AL+QI G
Sbjct: 173 --FSESCG-----------LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILG 219

Query: 256 ICLAQNL 262
           +  A  +
Sbjct: 220 LTFAMTM 226


>gi|68800024 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  103 bits (258), Expect = 1e-22
 Identities = 71/247 (28%), Positives = 108/247 (43%), Gaps = 32/247 (12%)

Query: 18  KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVL 77
           KY +F FN++FW+ G   L +G+W    +G  + +S+      L    L ++ G  +  +
Sbjct: 10  KYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSS--SFPSLSAANLLIITGAFVMAI 67

Query: 78  GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAY- 136
           GF GC+GA++EN  LL  F + L L+F LE    IL F + D I       +   +  Y 
Sbjct: 68  GFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYG 127

Query: 137 -RDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAE 195
            + ++ L N     Q  + CCG     DW   +Y      N +R    VP SCC+     
Sbjct: 128 TQGNVGLTNAWSIIQTDFRCCGVSNYTDW-FEVY------NATR----VPDSCCLE---- 172

Query: 196 DVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFG 255
              +  CG           L   G      C    + WLQ+NL+ V    +  AL+QI G
Sbjct: 173 --FSESCG-----------LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILG 219

Query: 256 ICLAQNL 262
           +  A  +
Sbjct: 220 LTFAMTM 226


>gi|68800011 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  103 bits (258), Expect = 1e-22
 Identities = 71/247 (28%), Positives = 108/247 (43%), Gaps = 32/247 (12%)

Query: 18  KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVL 77
           KY +F FN++FW+ G   L +G+W    +G  + +S+      L    L ++ G  +  +
Sbjct: 10  KYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSS--SFPSLSAANLLIITGAFVMAI 67

Query: 78  GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAY- 136
           GF GC+GA++EN  LL  F + L L+F LE    IL F + D I       +   +  Y 
Sbjct: 68  GFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYG 127

Query: 137 -RDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAE 195
            + ++ L N     Q  + CCG     DW   +Y      N +R    VP SCC+     
Sbjct: 128 TQGNVGLTNAWSIIQTDFRCCGVSNYTDW-FEVY------NATR----VPDSCCLE---- 172

Query: 196 DVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFG 255
              +  CG           L   G      C    + WLQ+NL+ V    +  AL+QI G
Sbjct: 173 --FSESCG-----------LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILG 219

Query: 256 ICLAQNL 262
           +  A  +
Sbjct: 220 LTFAMTM 226


>gi|68799997 tetraspanin 4 isoform a [Homo sapiens]
          Length = 238

 Score =  103 bits (258), Expect = 1e-22
 Identities = 71/247 (28%), Positives = 108/247 (43%), Gaps = 32/247 (12%)

Query: 18  KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVL 77
           KY +F FN++FW+ G   L +G+W    +G  + +S+      L    L ++ G  +  +
Sbjct: 10  KYLMFAFNLLFWLGGCGVLGVGIWLAATQGSFATLSS--SFPSLSAANLLIITGAFVMAI 67

Query: 78  GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAY- 136
           GF GC+GA++EN  LL  F + L L+F LE    IL F + D I       +   +  Y 
Sbjct: 68  GFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYG 127

Query: 137 -RDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAE 195
            + ++ L N     Q  + CCG     DW   +Y      N +R    VP SCC+     
Sbjct: 128 TQGNVGLTNAWSIIQTDFRCCGVSNYTDW-FEVY------NATR----VPDSCCLE---- 172

Query: 196 DVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFG 255
              +  CG           L   G      C    + WLQ+NL+ V    +  AL+QI G
Sbjct: 173 --FSESCG-----------LHAPGTWWKAPCYETVKVWLQENLLAVGIFGLCTALVQILG 219

Query: 256 ICLAQNL 262
           +  A  +
Sbjct: 220 LTFAMTM 226


>gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens]
          Length = 245

 Score =  101 bits (252), Expect = 6e-22
 Identities = 72/265 (27%), Positives = 116/265 (43%), Gaps = 31/265 (11%)

Query: 1   MPGKHQHFQEPEVGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGG 60
           M    +  Q   V  C K  L  +  +FW+ G + LA+G+W    K  L N  +L +   
Sbjct: 1   MASPSRRLQTKPVITCFKSVLLIYTFIFWITGVILLAVGIWG---KVSLENYFSLLNEKA 57

Query: 61  LDPVWLFVVVGGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDW 120
            +  ++ +  G V+ +LG  GC    R + ++LK +++FL L+F +EL   I+ FVF+  
Sbjct: 58  TNVPFVLIATGTVIILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHE 117

Query: 121 IRDQLNLFINNNVKAYRDDIDLQ-NLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSR 179
           I++         +K Y    D + + +D  Q    CCG     DW        TD N   
Sbjct: 118 IKNSFKNNYEKALKQYNSTGDYRSHAVDKIQNTLHCCGVTDYRDW--------TDTNYYS 169

Query: 180 ERCGVPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLI 239
           E+ G P SCC     ED    +                   ++ +GC  +    ++  + 
Sbjct: 170 EK-GFPKSCC---KLEDCTPQR---------------DADKVNNEGCFIKVMTIIESEMG 210

Query: 240 VVAGVFMGIALLQIFGICLAQNLEQ 264
           VVAG+  G+A  Q+ GI LA  L +
Sbjct: 211 VVAGISFGVACFQLIGIFLAYCLSR 235


>gi|72534746 tetraspanin 18 isoform 1 [Homo sapiens]
          Length = 267

 Score =  100 bits (249), Expect = 1e-21
 Identities = 63/185 (34%), Positives = 92/185 (49%), Gaps = 18/185 (9%)

Query: 16  CGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMS 75
           C KY +F FN   ++ GA  LAIG+W   +      I A   L  L   ++ + +GG++ 
Sbjct: 8   CMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLL-LTGAYILLAMGGLLF 66

Query: 76  VLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKA 135
           +LGF GC GA+REN  LL FF +F+ +IF  EL+  ILAF+F++ +  +   F     K 
Sbjct: 67  LLGFLGCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTRE--FFTKELTKH 124

Query: 136 YRDDIDLQNLIDFAQEYWS-------CCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSC 188
           Y+ + D     D     W+       CCG  GP D+     F    L+       VP +C
Sbjct: 125 YQGNND----TDVFSATWNSVMITFGCCGVNGPEDFKFASVFRLLTLDSEE----VPEAC 176

Query: 189 CVRDP 193
           C R+P
Sbjct: 177 CRREP 181


>gi|122937466 tetraspanin 11 [Homo sapiens]
          Length = 253

 Score = 99.8 bits (247), Expect = 2e-21
 Identities = 77/258 (29%), Positives = 119/258 (46%), Gaps = 35/258 (13%)

Query: 18  KYFLFGFNIVFWVLGALFLAIGLWAWGEK-GVLSNISALTDLGGLDPVWLFVVVGGVMSV 76
           KY LF FN  FWV GA  LA+G+W   EK G LS +++ T        ++ +  G ++ V
Sbjct: 17  KYLLFVFNFFFWVGGAAVLAVGIWTLVEKSGYLSVLASSTFAAS---AYILIFAGVLVMV 73

Query: 77  LGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVK-- 134
            GF G    L E    L  +   L +IF +EL  G+LA V+   + D+L   +N  +   
Sbjct: 74  TGFLGFGAILWERKGCLSTYFCLLLVIFLVELVAGVLAHVYYQRLSDELKQHLNRTLAEN 133

Query: 135 -AYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDP 193
                   +   +D  Q+ + CCG+    DW  + Y     L    E   VP SCC    
Sbjct: 134 YGQPGATQITASVDRLQQDFKCCGSNSSADWQHSTYI----LLREAEGRQVPDSCC---- 185

Query: 194 AEDVLNTQCG---YDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIAL 250
               +  +CG   +   +  V G           GC+ + E++L D+L+++  V +G+A 
Sbjct: 186 --KTVVVRCGQRAHPSNIYKVEG-----------GCLTKLEQFLADHLLLMGAVGIGVAC 232

Query: 251 LQIFGI----CLAQNLEQ 264
           LQI G+    CL Q L++
Sbjct: 233 LQICGMVLTCCLHQRLQR 250


>gi|67782354 CD82 antigen isoform 2 [Homo sapiens]
          Length = 242

 Score = 97.4 bits (241), Expect = 1e-20
 Identities = 65/244 (26%), Positives = 117/244 (47%), Gaps = 31/244 (12%)

Query: 18  KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLDPVWLFVVVGGVMSVL 77
           KYFLF FN++F++LGA+ L  G+W   +K    ++   +        ++F+ VG V  ++
Sbjct: 10  KYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFIGVGAVTMLM 69

Query: 78  GFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKAYR 137
           GF GCIGA+ E   LL      +G         GI+  + +D+              + R
Sbjct: 70  GFLGCIGAVNEVRCLLGLLKQEMG---------GIVTELIRDY-------------NSSR 107

Query: 138 DDIDLQNLIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAEDV 197
           +D  LQ+  D+ Q    CCG     +W  N          +R     P SC V+   ++ 
Sbjct: 108 ED-SLQDAWDYVQAQVKCCGWVSFYNWTDNAELM------NRPEVTYPCSCEVKGEEDNS 160

Query: 198 LNTQCGYDVRL--KLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVAGVFMGIALLQIFG 255
           L+ + G+      +   G   +   ++ +GC+ + + WLQ+NL ++ GV +G+A++++ G
Sbjct: 161 LSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAIIELLG 220

Query: 256 ICLA 259
           + L+
Sbjct: 221 MVLS 224


>gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens]
          Length = 237

 Score = 97.1 bits (240), Expect = 1e-20
 Identities = 73/260 (28%), Positives = 112/260 (43%), Gaps = 43/260 (16%)

Query: 13  VGCCGKYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLGGLD--PVWLFVVV 70
           V  C KY +F FN +FW+ G L LA+ +W        + I    D+G      V + + V
Sbjct: 4   VSACIKYSMFTFNFLFWLCGILILALAIWVRVSNDSQA-IFGSEDVGSSSYVAVDILIAV 62

Query: 71  GGVMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFIN 130
           G ++ +LGF GC GA++E+  +L  F + L LI  L++ATGIL  VFK      +N  + 
Sbjct: 63  GAIIMILGFLGCCGAIKESRCMLLLFFIGLLLILLLQVATGILGAVFKSKSDRIVNETLY 122

Query: 131 NNVKAY----RDDIDLQNLIDFAQEYWSCCG-ARGPNDWNLNIYFN---CTDLNPSRERC 182
            N K        +   Q  I   QE + CCG   G  DW  N       C  L+  R   
Sbjct: 123 ENTKLLSATGESEKQFQEAIIVFQEEFKCCGLVNGAADWGNNFQHYPELCACLDKQR--- 179

Query: 183 GVPFSCCVRDPAEDVLNTQCGYDVRLKLVRGELEQQGFIHTKGCVGQFEKWLQDNLIVVA 242
                     P +     Q                   ++ + C+   + +L  NLI+V 
Sbjct: 180 ----------PCQSYNGKQ-------------------VYKETCISFIKDFLAKNLIIVI 210

Query: 243 GVFMGIALLQIFGICLAQNL 262
           G+  G+A+++I G+  +  L
Sbjct: 211 GISFGLAVIEILGLVFSMVL 230


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.329    0.147    0.492 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,041,855
Number of Sequences: 37866
Number of extensions: 420891
Number of successful extensions: 1248
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1099
Number of HSP's gapped (non-prelim): 69
length of query: 266
length of database: 18,247,518
effective HSP length: 100
effective length of query: 166
effective length of database: 14,460,918
effective search space: 2400512388
effective search space used: 2400512388
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.