Search of human proteins with 54792073

Search of human proteins with 54792073

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|54792073 mucolipin 2 [Homo sapiens]
         (566 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|54792073 mucolipin 2 [Homo sapiens]                               1151   0.0  
gi|24496763 mucolipin 3 [Homo sapiens]                                654   0.0  
gi|10092597 mucolipin 1 [Homo sapiens]                                526   e-149
gi|4505835 polycystin 2 [Homo sapiens]                                 57   5e-08
gi|116812588 polycystic kidney disease 2-like 2 [Homo sapiens]         56   8e-08
gi|33598944 polycystic kidney disease 2-like 1 [Homo sapiens]          52   1e-06
gi|5174633 receptor for egg jelly-like protein precursor [Homo s...    45   2e-04
gi|62988334 cation channel, sperm associated 4 [Homo sapiens]          39   0.017
gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B ...    35   0.18 
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]         33   0.53 
gi|26051223 sperm-associated cation channel 2 isoform 2 [Homo sa...    32   1.6  
gi|16876443 sperm-associated cation channel 2 isoform 1 [Homo sa...    32   1.6  
gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo s...    32   2.0  
gi|187828880 calcium channel, alpha 1A subunit isoform 3 [Homo s...    32   2.0  
gi|33239443 synaptophysin-like 1 isoform b [Homo sapiens]              31   2.7  
gi|5803185 synaptophysin-like 1 isoform a [Homo sapiens]               31   2.7  
gi|24119274 voltage gated channel like 1 [Homo sapiens]                31   3.5  
gi|38505292 voltage-dependent calcium channel alpha 1G subunit i...    31   3.5  
gi|38505288 voltage-dependent calcium channel alpha 1G subunit i...    31   3.5  
gi|38505276 voltage-dependent calcium channel alpha 1G subunit i...    31   3.5  
gi|38505274 voltage-dependent calcium channel alpha 1G subunit i...    31   3.5  
gi|38505272 voltage-dependent calcium channel alpha 1G subunit i...    31   3.5  
gi|38505268 voltage-dependent calcium channel alpha 1G subunit i...    31   3.5  
gi|115583667 sodium channel, voltage-gated, type XI, alpha [Homo...    31   3.5  
gi|148612863 transient receptor potential cation channel, subfam...    30   7.7  

>gi|54792073 mucolipin 2 [Homo sapiens]
          Length = 566

 Score = 1151 bits (2977), Expect = 0.0
 Identities = 566/566 (100%), Positives = 566/566 (100%)

Query: 1   MARQPYRFPQARIPERGSGVFRLTVRNAMAHRDSEMKEECLREDLKFYFMSPCEKYRARR 60
           MARQPYRFPQARIPERGSGVFRLTVRNAMAHRDSEMKEECLREDLKFYFMSPCEKYRARR
Sbjct: 1   MARQPYRFPQARIPERGSGVFRLTVRNAMAHRDSEMKEECLREDLKFYFMSPCEKYRARR 60

Query: 61  QIPWKLGLQILKIVMVTTQLVRFGLSNQLVVAFKEDNTVAFKHLFLKGYSGTDEDDYSCS 120
           QIPWKLGLQILKIVMVTTQLVRFGLSNQLVVAFKEDNTVAFKHLFLKGYSGTDEDDYSCS
Sbjct: 61  QIPWKLGLQILKIVMVTTQLVRFGLSNQLVVAFKEDNTVAFKHLFLKGYSGTDEDDYSCS 120

Query: 121 VYTQEDAYESIFFAINQYHQLKDITLGTLGYGENEDNRIGLKVCKQHYKKGTMFPSNETL 180
           VYTQEDAYESIFFAINQYHQLKDITLGTLGYGENEDNRIGLKVCKQHYKKGTMFPSNETL
Sbjct: 121 VYTQEDAYESIFFAINQYHQLKDITLGTLGYGENEDNRIGLKVCKQHYKKGTMFPSNETL 180

Query: 181 NIDNDVELDCVQLDLQDLSKKPPDWKNSSFFRLEFYRLLQVEISFHLKGIDLQTIHSREL 240
           NIDNDVELDCVQLDLQDLSKKPPDWKNSSFFRLEFYRLLQVEISFHLKGIDLQTIHSREL
Sbjct: 181 NIDNDVELDCVQLDLQDLSKKPPDWKNSSFFRLEFYRLLQVEISFHLKGIDLQTIHSREL 240

Query: 241 PDCYVFQNTIIFDNKAHSGKIKIYFDSDAKIEECKDLNIFGSTQKNAQYVLVFDAFVIVI 300
           PDCYVFQNTIIFDNKAHSGKIKIYFDSDAKIEECKDLNIFGSTQKNAQYVLVFDAFVIVI
Sbjct: 241 PDCYVFQNTIIFDNKAHSGKIKIYFDSDAKIEECKDLNIFGSTQKNAQYVLVFDAFVIVI 300

Query: 301 CLASLILCTRSIVLALRLRKRFLNFFLEKYKRPVCDTDQWEFINGWYVLVIISDLMTIIG 360
           CLASLILCTRSIVLALRLRKRFLNFFLEKYKRPVCDTDQWEFINGWYVLVIISDLMTIIG
Sbjct: 301 CLASLILCTRSIVLALRLRKRFLNFFLEKYKRPVCDTDQWEFINGWYVLVIISDLMTIIG 360

Query: 361 SILKMEIKAKNLTNYDLCSIFLGTSTLLVWVGVIRYLGYFQAYNVLILTMQASLPKVLRF 420
           SILKMEIKAKNLTNYDLCSIFLGTSTLLVWVGVIRYLGYFQAYNVLILTMQASLPKVLRF
Sbjct: 361 SILKMEIKAKNLTNYDLCSIFLGTSTLLVWVGVIRYLGYFQAYNVLILTMQASLPKVLRF 420

Query: 421 CACAGMIYLGYTFCGWIVLGPYHDKFENLNTVAECLFSLVNGDDMFATFAQIQQKSILVW 480
           CACAGMIYLGYTFCGWIVLGPYHDKFENLNTVAECLFSLVNGDDMFATFAQIQQKSILVW
Sbjct: 421 CACAGMIYLGYTFCGWIVLGPYHDKFENLNTVAECLFSLVNGDDMFATFAQIQQKSILVW 480

Query: 481 LFSRLYLYSFISLFIYMILSLFIALITDSYDTIKKFQQNGFPETDLQEFLKECSSKEEYQ 540
           LFSRLYLYSFISLFIYMILSLFIALITDSYDTIKKFQQNGFPETDLQEFLKECSSKEEYQ
Sbjct: 481 LFSRLYLYSFISLFIYMILSLFIALITDSYDTIKKFQQNGFPETDLQEFLKECSSKEEYQ 540

Query: 541 KESSAFLSCICCRRRKRSDDHLIPIS 566
           KESSAFLSCICCRRRKRSDDHLIPIS
Sbjct: 541 KESSAFLSCICCRRRKRSDDHLIPIS 566


>gi|24496763 mucolipin 3 [Homo sapiens]
          Length = 553

 Score =  654 bits (1686), Expect = 0.0
 Identities = 310/521 (59%), Positives = 404/521 (77%), Gaps = 5/521 (0%)

Query: 38  EECLREDLKFYFMSPCEKYRARRQIPWKLGLQILKIVMVTTQLVRFGLSNQLVVAFKEDN 97
           E+ +R  LKF+FM+PCEK+ AR + PWKL +QILKI MVT QLV FGLSNQ+VVAFKE+N
Sbjct: 35  EDQMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEEN 94

Query: 98  TVAFKHLFLKGYSGTDEDDYSCSVYTQEDAYESIFFAINQYHQLKDITLGTLGYGENEDN 157
           T+AFKHLFLKGY    +D Y+  VYTQ D Y+ + FA+NQY QL ++++G   Y      
Sbjct: 95  TIAFKHLFLKGYMDRMDDTYA--VYTQSDVYDQLIFAVNQYLQLYNVSVGNHAYENKGTK 152

Query: 158 RIGLKVCKQHYKKGTMFPSNETLNIDNDVELDCVQLDLQDLSKKPPDWKNSSFFRLEFYR 217
           +  + +C+  YK+G ++P N+T +ID ++E +C  ++  +        +N     L+F+R
Sbjct: 153 QSAMAICQHFYKRGNIYPGNDTFDIDPEIETECFFVEPDEPFHIGTPAENKLNLTLDFHR 212

Query: 218 LLQVEISFHLKGIDLQTIHSRELPDCYVFQNTIIFDNKAHSGKIKIYFDSDAKIEECKDL 277
           LL VE+ F LK I+LQT+  +ELPDCY F  TI FDNKAHSG+IKI  D+D  I ECKD 
Sbjct: 213 LLTVELQFKLKAINLQTVRHQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIRECKDW 272

Query: 278 NIFGSTQKNAQYVLVFDAFVIVICLASLILCTRSIVLALRLRKRFLNFFLEKYKRPVCDT 337
           ++ GS QKN  Y+++FDAFVI+ CL SLILC RS++  L+L++ F+NFFL  YK+ V  +
Sbjct: 273 HVSGSIQKNTHYMMIFDAFVILTCLVSLILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVS 332

Query: 338 DQWEFINGWYVLVIISDLMTIIGSILKMEIKAKNLTNYDLCSIFLGTSTLLVWVGVIRYL 397
           DQ EF+NGWY+++IISD++TIIGSILKMEI+AK+LT+YD+CSI LGTST+LVW+GVIRYL
Sbjct: 333 DQMEFVNGWYIMIIISDILTIIGSILKMEIQAKSLTSYDVCSILLGTSTMLVWLGVIRYL 392

Query: 398 GYFQAYNVLILTMQASLPKVLRFCACAGMIYLGYTFCGWIVLGPYHDKFENLNTVAECLF 457
           G+F  YN+LILT+QA+LP V+RFC CA MIYLGY FCGWIVLGPYHDKF +LN V+ECLF
Sbjct: 393 GFFAKYNLLILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLGPYHDKFRSLNMVSECLF 452

Query: 458 SLVNGDDMFATFAQIQQKSILVWLFSRLYLYSFISLFIYMILSLFIALITDSYDTIKKFQ 517
           SL+NGDDMFATFA++QQKS LVWLFSR+YLYSFISLFIYMILSLFIALITD+Y+TIK++Q
Sbjct: 453 SLINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFIYMILSLFIALITDTYETIKQYQ 512

Query: 518 QNGFPETDLQEFLKECS---SKEEYQKESSAFLSCICCRRR 555
           Q+GFPET+L+ F+ EC    +  +Y+ E    +S  CC ++
Sbjct: 513 QDGFPETELRTFISECKDLPNSGKYRLEDDPPVSLFCCCKK 553


>gi|10092597 mucolipin 1 [Homo sapiens]
          Length = 580

 Score =  526 bits (1356), Expect = e-149
 Identities = 266/548 (48%), Positives = 382/548 (69%), Gaps = 22/548 (4%)

Query: 37  KEECLREDLKFYFMSPCEKYRARRQIPWKLGLQILKIVMVTTQLVRFGLSNQLVVAFKED 96
           +EE LR  LK++FMSPC+K+RA+ + P KL LQ++KI++VT QL+ FGLSNQL V F+E+
Sbjct: 37  EEEDLRRRLKYFFMSPCDKFRAKGRKPCKLMLQVVKILVVTVQLILFGLSNQLAVTFREE 96

Query: 97  NTVAFKHLFLKGYSGTDEDDYSCSVYTQEDAYESIFFAINQYHQLKDITLGTLGY----G 152
           NT+AF+HLFL GYS   +D ++   YT+E  Y++IF A++QY  L D++LG   Y    G
Sbjct: 97  NTIAFRHLFLLGYSDGADDTFAA--YTREQLYQAIFHAVDQYLALPDVSLGRYAYVRGGG 154

Query: 153 ENEDNRIGLKVCKQHYKKGTMFPSNETLNIDNDVELDCVQLDLQDLSKKPPD-----WKN 207
           +   N  GL +C+++Y +G + P+N+T +ID  V  DC+Q+D  +    PP       ++
Sbjct: 155 DPWTNGSGLALCQRYYHRGHVDPANDTFDIDPMVVTDCIQVDPPERPPPPPSDDLTLLES 214

Query: 208 SSFFR---LEFYRLLQVEISFHLKGIDLQTIHSRELPDCYVFQNTIIFDNKAHSGKIKIY 264
           SS ++   L+F++L+ V I F LK I+LQ++ + E+PDCY F   I FDNKAHSG+I I 
Sbjct: 215 SSSYKNLTLKFHKLVNVTIHFRLKTINLQSLINNEIPDCYTFSVLITFDNKAHSGRIPIS 274

Query: 265 FDSDAKIEECKDLNIFGSTQKNAQYVLVFDAFVIVICLASLILCTRSIVLALRLRKRFLN 324
            ++ A I+ECK  ++F     +  + L+FD  VI+ C  S +LC RS++    L+  F+ 
Sbjct: 275 LETQAHIQECKHPSVFQHGDNS--FRLLFDVVVILTCSLSFLLCARSLLRGFLLQNEFVG 332

Query: 325 FFLEKYKRPVCDTDQWEFINGWYVLVIISDLMTIIGSILKMEIKAKNLTNYDLCSIFLGT 384
           F   +  R +   ++ EF+NGWY+L++ SD++TI G+I+K+ I+AKNL +YD+CSI LGT
Sbjct: 333 FMWRQRGRVISLWERLEFVNGWYILLVTSDVLTISGTIMKIGIEAKNLASYDVCSILLGT 392

Query: 385 STLLVWVGVIRYLGYFQAYNVLILTMQASLPKVLRFCACAGMIYLGYTFCGWIVLGPYHD 444
           STLLVWVGVIRYL +F  YN+LI T++ +LP V+RFC C  +IYLGY FCGWIVLGPYH 
Sbjct: 393 STLLVWVGVIRYLTFFHNYNILIATLRVALPSVMRFCCCVAVIYLGYCFCGWIVLGPYHV 452

Query: 445 KFENLNTVAECLFSLVNGDDMFATFAQIQQ---KSILVWLFSRLYLYSFISLFIYMILSL 501
           KF +L+ V+ECLFSL+NGDDMF TFA +Q    +S LVWLFS+LYLYSFISLFIYM+LSL
Sbjct: 453 KFRSLSMVSECLFSLINGDDMFVTFAAMQAQQGRSSLVWLFSQLYLYSFISLFIYMVLSL 512

Query: 502 FIALITDSYDTIKKFQQNGFPETDLQEFLKECS---SKEEYQKESSAFLSCICCRRRKRS 558
           FIALIT +YDTIK     G  E++LQ ++ +C    +  ++++ S +  S +CC  R  S
Sbjct: 513 FIALITGAYDTIKHPGGAGAEESELQAYIAQCQDSPTSGKFRRGSGSACSLLCCCGRDPS 572

Query: 559 DDHLIPIS 566
           ++H + ++
Sbjct: 573 EEHSLLVN 580


>gi|4505835 polycystin 2 [Homo sapiens]
          Length = 968

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 33/151 (21%), Positives = 75/151 (49%), Gaps = 12/151 (7%)

Query: 385 STLLVWVGVIRYLGYFQAYNVLILTMQASLPKVLRFCACAGMIYLGYTFCGWIVLGPYHD 444
           +   VW+ + +++ + +  + L  TM      +  F     +I+L Y    ++V G   D
Sbjct: 565 TVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQVD 624

Query: 445 KFENLNTVAECLFS---LVNGDDMFATFAQIQQKSILVWLFSRLYLYSFISLFIYMILSL 501
            F   +T  EC+F+   ++ GD     FA+I++ + ++     +Y  +F+    +++L++
Sbjct: 625 DF---STFQECIFTQFRIILGD---INFAEIEEANRVL---GPIYFTTFVFFMFFILLNM 675

Query: 502 FIALITDSYDTIKKFQQNGFPETDLQEFLKE 532
           F+A+I D+Y  +K        E +L + +++
Sbjct: 676 FLAIINDTYSEVKSDLAQQKAEMELSDLIRK 706


>gi|116812588 polycystic kidney disease 2-like 2 [Homo sapiens]
          Length = 613

 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 35/164 (21%), Positives = 74/164 (45%), Gaps = 10/164 (6%)

Query: 355 LMTIIGSILKMEIKAKNLTNYDLCSIF----LGTSTLLVWVGVIRYLGYFQAYNVLILTM 410
           +  ++G +LK   K  +        I+    +  +    W+ + +++ + +  + L  T+
Sbjct: 341 IFLLLGQLLKSTEKYSDFYFLACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTL 400

Query: 411 QASLPKVLRFCACAGMIYLGYTFCGWIVLGPYHDKFENLNTVAECLFSLVNGDDMFATFA 470
              +  ++ F     +I+  Y   G++V G   D F          F +V GD     FA
Sbjct: 401 SRCVKDIVGFAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGD---FNFA 457

Query: 471 QIQQKSILVWLFSRLYLYSFISLFIYMILSLFIALITDSYDTIK 514
            IQQ + ++     +Y  +FI    +++L++F+A+I D+Y  +K
Sbjct: 458 GIQQANPIL---GPIYFITFIFFVFFVLLNMFLAIINDTYSEVK 498


>gi|33598944 polycystic kidney disease 2-like 1 [Homo sapiens]
          Length = 805

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 29/150 (19%), Positives = 69/150 (46%), Gaps = 12/150 (8%)

Query: 390 WVGVIRYLGYFQAYNVLILTMQASLPKVLRFCACAGMIYLGYTFCGWIVLGPYHDKFENL 449
           W+ + +Y+ + +    L  T+      +L F     +++  Y   G+++ G    + EN 
Sbjct: 450 WIKIFKYISFNKTMTQLSSTLARCAKDILGFAVMFFIVFFAYAQLGYLLFGT---QVENF 506

Query: 450 NTVAECLFS---LVNGDDMFATFAQIQQKSILVWLFSRLYLYSFISLFIYMILSLFIALI 506
           +T  +C+F+   ++ GD  +       +      +    Y  +++    +++L++F+A+I
Sbjct: 507 STFIKCIFTQFRIILGDFDYNAIDNANR------ILGPAYFVTYVFFVFFVLLNMFLAII 560

Query: 507 TDSYDTIKKFQQNGFPETDLQEFLKECSSK 536
            D+Y  +K+       E  L + LK+  +K
Sbjct: 561 NDTYSEVKEELAGQKDELQLSDLLKQGYNK 590


>gi|5174633 receptor for egg jelly-like protein precursor [Homo
            sapiens]
          Length = 2253

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 31/136 (22%), Positives = 61/136 (44%), Gaps = 7/136 (5%)

Query: 380  IFLGTSTLLVWVGVIRYLGYFQAYNVLILTMQASLPKVLRFCACAGMIYLGYTFCGWIVL 439
            I LG    L  +  +RY  +F    +    +QA+LP +        + +  Y   G++V 
Sbjct: 2052 IILGFLLFLTILKTLRYSRFFYDVRLAQRAIQAALPGICHMAFVVSVYFFVYMAFGYLVF 2111

Query: 440  GPYHDKFENLNTVAECLFSLVNGDDMFATFAQIQQKSILVWLFSRLYLYSFISLFIYMIL 499
            G +   + NL    + +FS          F+  +       +   L+L SF+ + I +++
Sbjct: 2112 GQHEWNYSNLIHSTQTVFSYCVSAFQNTEFSNNR-------ILGVLFLSSFMLVMICVLI 2164

Query: 500  SLFIALITDSYDTIKK 515
            +LF A+I  +Y+ +K+
Sbjct: 2165 NLFQAVILSAYEEMKQ 2180


>gi|62988334 cation channel, sperm associated 4 [Homo sapiens]
          Length = 472

 Score = 38.5 bits (88), Expect = 0.017
 Identities = 29/155 (18%), Positives = 70/155 (45%), Gaps = 8/155 (5%)

Query: 406 LILTMQASLPKVLRFCACAGMIYLGYTFCGWIVLGPYHDK-FENLNTVAECLFSLVNGD- 463
           +I  +  S+P +           L ++  G  + G +  K F+N+      LF  +  D 
Sbjct: 203 IIRVILQSVPDMANIMVLILFFMLVFSVFGVTLFGAFVPKHFQNIQVALYTLFICITQDG 262

Query: 464 --DMFATFAQIQQKSILVWLFSRLYLYSFISLFIYMILSLFIALITDSYDTIKKFQQNGF 521
             D+++ F Q +++   + +   +Y   FI++  ++ ++LF+ ++T + + + K  + G 
Sbjct: 263 WVDIYSDF-QTEKREYAMEIGGAIYFTIFITIGAFIGINLFVIVVTTNLEQMMKAGEQGQ 321

Query: 522 PETDLQEFLKECSSKEEYQKESSAFLSCICCRRRK 556
            +   +    E  ++EE + +    + C+  R  K
Sbjct: 322 QQ---RITFSETGAEEEEENDQLPLVHCVVARSEK 353


>gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B
            subunit [Homo sapiens]
          Length = 2339

 Score = 35.0 bits (79), Expect = 0.18
 Identities = 43/193 (22%), Positives = 74/193 (38%), Gaps = 26/193 (13%)

Query: 342  FINGWYVLVIISDLMTIIGSILKMEIKAKNLTNYDLCSIFLGTSTLLVWVGVIRYLGYFQ 401
            F + W V     D +T++GSI  + +     TN  +   FL    L     +I+ L    
Sbjct: 1531 FRDAWNVF----DFVTVLGSITDILVTEIAETNNFINLSFL---RLFRAARLIKLLRQGY 1583

Query: 402  AYNVLILTMQASLPKVLRFCACAGMIYLGYTFCGWIVLGPY----------HDKFENLNT 451
               +L+ T   S   +   C    M++  Y   G  V G            H+ F     
Sbjct: 1584 TIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQ 1643

Query: 452  VAECLFSLVNGD-------DMFATFAQIQQKSILVWL--FSRLYLYSFISLFIYMILSLF 502
                LF    G+          +  A  +Q +       F+  Y  SFI L  +++L+LF
Sbjct: 1644 ALMLLFRSATGEAWHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLCSFLMLNLF 1703

Query: 503  IALITDSYDTIKK 515
            +A+I D+++ + +
Sbjct: 1704 VAVIMDNFEYLTR 1716


>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
          Length = 1312

 Score = 33.5 bits (75), Expect = 0.53
 Identities = 16/33 (48%), Positives = 20/33 (60%)

Query: 113  DEDDYSCSVYTQEDAYESIFFAINQYHQLKDIT 145
            D D Y   ++TQE A E +  AI  Y+Q KDIT
Sbjct: 1203 DTDKYLKKLHTQERAVEEVKLAIKPYYQKKDIT 1235


>gi|26051223 sperm-associated cation channel 2 isoform 2 [Homo
           sapiens]
          Length = 530

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 37/202 (18%), Positives = 76/202 (37%), Gaps = 32/202 (15%)

Query: 380 IFLGTSTLLVWVGVIRY---------LGYFQAYNVLILTMQASLPKVLRFCACAGMIYLG 430
           + +G +   VW+ ++R          L  F+   ++IL +  +L  +        + +  
Sbjct: 195 VLVGVTGQSVWLQLLRICRVLRSLKLLAQFRQIQIIILVLVRALKSMTFLLMLLLIFFYI 254

Query: 431 YTFCGWIVLGPY----------HDKFENLNTVAECLFSLVNGDDMFATFAQIQQKSILVW 480
           +   G  V   Y          H  F +L      +F L   D  +A    + +   +  
Sbjct: 255 FAVTGVYVFSEYTRSPRQDLEYHVFFSDLPNSLVTVFILFTLDHWYALLQDVWKVPEVSR 314

Query: 481 LFSRLYLYSFISLFIYMILSLFIALITDSYDTIKKFQQNGFPETDLQEFLKECSSKEEYQ 540
           +FS +Y   ++ L   +  S+ +A++  ++  I+K              L E  ++ E Q
Sbjct: 315 IFSSIYFILWLLLGSIIFRSIIVAMMVTNFQNIRK-------------ELNEEMARREVQ 361

Query: 541 KESSAFLSCICCRRRKRSDDHL 562
            ++  F   I  RR+  S + L
Sbjct: 362 LKADMFKRQIIQRRKNMSHEAL 383


>gi|16876443 sperm-associated cation channel 2 isoform 1 [Homo
           sapiens]
          Length = 528

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 37/202 (18%), Positives = 76/202 (37%), Gaps = 32/202 (15%)

Query: 380 IFLGTSTLLVWVGVIRY---------LGYFQAYNVLILTMQASLPKVLRFCACAGMIYLG 430
           + +G +   VW+ ++R          L  F+   ++IL +  +L  +        + +  
Sbjct: 195 VLVGVTGQSVWLQLLRICRVLRSLKLLAQFRQIQIIILVLVRALKSMTFLLMLLLIFFYI 254

Query: 431 YTFCGWIVLGPY----------HDKFENLNTVAECLFSLVNGDDMFATFAQIQQKSILVW 480
           +   G  V   Y          H  F +L      +F L   D  +A    + +   +  
Sbjct: 255 FAVTGVYVFSEYTRSPRQDLEYHVFFSDLPNSLVTVFILFTLDHWYALLQDVWKVPEVSR 314

Query: 481 LFSRLYLYSFISLFIYMILSLFIALITDSYDTIKKFQQNGFPETDLQEFLKECSSKEEYQ 540
           +FS +Y   ++ L   +  S+ +A++  ++  I+K              L E  ++ E Q
Sbjct: 315 IFSSIYFILWLLLGSIIFRSIIVAMMVTNFQNIRK-------------ELNEEMARREVQ 361

Query: 541 KESSAFLSCICCRRRKRSDDHL 562
            ++  F   I  RR+  S + L
Sbjct: 362 LKADMFKRQIIQRRKNMSHEAL 383


>gi|187828892 calcium channel, alpha 1A subunit isoform 4 [Homo
            sapiens]
          Length = 2506

 Score = 31.6 bits (70), Expect = 2.0
 Identities = 39/195 (20%), Positives = 67/195 (34%), Gaps = 38/195 (19%)

Query: 352  ISDLMTIIGSILKMEIK--AKNLTNYDLCSIFLGTSTLLVWVGVIRYLGYFQAYNVLILT 409
            I D +T++GSI  + +     N  N     +F           +I+ L       +L+ T
Sbjct: 1631 IFDFVTVLGSITDILVTEFGNNFINLSFLRLFRAAR-------LIKLLRQGYTIRILLWT 1683

Query: 410  MQASLPKVLRFCACAGMIYLGYTFCGWIVLGPY------------------HDKFENLNT 451
               S   +   C    M++  Y   G  V G                    H+ F     
Sbjct: 1684 FVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIGIDVEDEDSDEDEFQITEHNNFRTFFQ 1743

Query: 452  VAECLFSLVNGDDMFATFAQI-------QQKSILVWL----FSRLYLYSFISLFIYMILS 500
                LF    G+                +   IL       F+  Y  SFI L  +++L+
Sbjct: 1744 ALMLLFRSATGEAWHNIMLSCLSGKPCDKNSGILTRECGNEFAYFYFVSFIFLCSFLMLN 1803

Query: 501  LFIALITDSYDTIKK 515
            LF+A+I D+++ + +
Sbjct: 1804 LFVAVIMDNFEYLTR 1818


>gi|187828880 calcium channel, alpha 1A subunit isoform 3 [Homo
            sapiens]
          Length = 2261

 Score = 31.6 bits (70), Expect = 2.0
 Identities = 39/195 (20%), Positives = 67/195 (34%), Gaps = 38/195 (19%)

Query: 352  ISDLMTIIGSILKMEIK--AKNLTNYDLCSIFLGTSTLLVWVGVIRYLGYFQAYNVLILT 409
            I D +T++GSI  + +     N  N     +F           +I+ L       +L+ T
Sbjct: 1632 IFDFVTVLGSITDILVTEFGNNFINLSFLRLFRAAR-------LIKLLRQGYTIRILLWT 1684

Query: 410  MQASLPKVLRFCACAGMIYLGYTFCGWIVLGPY------------------HDKFENLNT 451
               S   +   C    M++  Y   G  V G                    H+ F     
Sbjct: 1685 FVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIGIDVEDEDSDEDEFQITEHNNFRTFFQ 1744

Query: 452  VAECLFSLVNGDDMFATFAQI-------QQKSILVWL----FSRLYLYSFISLFIYMILS 500
                LF    G+                +   IL       F+  Y  SFI L  +++L+
Sbjct: 1745 ALMLLFRSATGEAWHNIMLSCLSGKPCDKNSGILTRECGNEFAYFYFVSFIFLCSFLMLN 1804

Query: 501  LFIALITDSYDTIKK 515
            LF+A+I D+++ + +
Sbjct: 1805 LFVAVIMDNFEYLTR 1819


>gi|33239443 synaptophysin-like 1 isoform b [Homo sapiens]
          Length = 241

 Score = 31.2 bits (69), Expect = 2.7
 Identities = 16/46 (34%), Positives = 24/46 (52%)

Query: 275 KDLNIFGSTQKNAQYVLVFDAFVIVICLASLILCTRSIVLALRLRK 320
           KD  + G    +AQ+ + F  FV + C+A+L+L      L L  RK
Sbjct: 85  KDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVGYTSLYLDSRK 130


>gi|5803185 synaptophysin-like 1 isoform a [Homo sapiens]
          Length = 259

 Score = 31.2 bits (69), Expect = 2.7
 Identities = 16/46 (34%), Positives = 24/46 (52%)

Query: 275 KDLNIFGSTQKNAQYVLVFDAFVIVICLASLILCTRSIVLALRLRK 320
           KD  + G    +AQ+ + F  FV + C+A+L+L      L L  RK
Sbjct: 103 KDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVGYTSLYLDSRK 148


>gi|24119274 voltage gated channel like 1 [Homo sapiens]
          Length = 1738

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 28/128 (21%), Positives = 50/128 (39%), Gaps = 22/128 (17%)

Query: 405  VLILTMQASLPKVLRFCACAGMIYLGYTFCGWIVLGPY--------HDKFENLNTVAECL 456
            +L+LT+  S+ K         ++ L Y F G ++ G          H  F +       L
Sbjct: 1323 MLLLTVVVSMYKSFFIIVGMFLLLLCYAFAGVVLFGTVKYGENINRHANFSSAGKAITVL 1382

Query: 457  FSLVNGDD----MFATFAQ---IQQKSILVWLF-------SRLYLYSFISLFIYMILSLF 502
            F +V G+D    M     Q           W         + +Y  SF  +  Y++L+L 
Sbjct: 1383 FRIVTGEDWNKIMHDCMVQPPFCTPDEFTYWATDCGNYAGALMYFCSFYVIIAYIMLNLL 1442

Query: 503  IALITDSY 510
            +A+I +++
Sbjct: 1443 VAIIVENF 1450


>gi|38505292 voltage-dependent calcium channel alpha 1G subunit
            isoform 3 [Homo sapiens]
          Length = 2343

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 21/113 (18%), Positives = 48/113 (42%), Gaps = 11/113 (9%)

Query: 446  FENLNTVAECLFSLVNGDDMFATFAQ------IQQKSIL---VWLFSRLYLYSFISLFIY 496
            F+NL      LF L + D              + Q+ I+    W+   LY  SF+ +  +
Sbjct: 1446 FDNLGQALMSLFVLASKDGWVDIMYDGLDAVGVDQQPIMNHNPWML--LYFISFLLIVAF 1503

Query: 497  MILSLFIALITDSYDTIKKFQQNGFPETDLQEFLKECSSKEEYQKESSAFLSC 549
             +L++F+ ++ +++   ++ Q+        ++ L+    K   +++  A   C
Sbjct: 1504 FVLNMFVGVVVENFHKCRQHQEEEEARRREEKRLRRLEKKRRSKEKQMAEAQC 1556


>gi|38505288 voltage-dependent calcium channel alpha 1G subunit
            isoform 12 [Homo sapiens]
          Length = 2250

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 21/113 (18%), Positives = 48/113 (42%), Gaps = 11/113 (9%)

Query: 446  FENLNTVAECLFSLVNGDDMFATFAQ------IQQKSIL---VWLFSRLYLYSFISLFIY 496
            F+NL      LF L + D              + Q+ I+    W+   LY  SF+ +  +
Sbjct: 1446 FDNLGQALMSLFVLASKDGWVDIMYDGLDAVGVDQQPIMNHNPWML--LYFISFLLIVAF 1503

Query: 497  MILSLFIALITDSYDTIKKFQQNGFPETDLQEFLKECSSKEEYQKESSAFLSC 549
             +L++F+ ++ +++   ++ Q+        ++ L+    K   +++  A   C
Sbjct: 1504 FVLNMFVGVVVENFHKCRQHQEEEEARRREEKRLRRLEKKRRSKEKQMAEAQC 1556


>gi|38505276 voltage-dependent calcium channel alpha 1G subunit
            isoform 5 [Homo sapiens]
          Length = 2321

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 21/113 (18%), Positives = 48/113 (42%), Gaps = 11/113 (9%)

Query: 446  FENLNTVAECLFSLVNGDDMFATFAQ------IQQKSIL---VWLFSRLYLYSFISLFIY 496
            F+NL      LF L + D              + Q+ I+    W+   LY  SF+ +  +
Sbjct: 1469 FDNLGQALMSLFVLASKDGWVDIMYDGLDAVGVDQQPIMNHNPWML--LYFISFLLIVAF 1526

Query: 497  MILSLFIALITDSYDTIKKFQQNGFPETDLQEFLKECSSKEEYQKESSAFLSC 549
             +L++F+ ++ +++   ++ Q+        ++ L+    K   +++  A   C
Sbjct: 1527 FVLNMFVGVVVENFHKCRQHQEEEEARRREEKRLRRLEKKRRSKEKQMAEAQC 1579


>gi|38505274 voltage-dependent calcium channel alpha 1G subunit
            isoform 7 [Homo sapiens]
          Length = 2298

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 21/113 (18%), Positives = 48/113 (42%), Gaps = 11/113 (9%)

Query: 446  FENLNTVAECLFSLVNGDDMFATFAQ------IQQKSIL---VWLFSRLYLYSFISLFIY 496
            F+NL      LF L + D              + Q+ I+    W+   LY  SF+ +  +
Sbjct: 1446 FDNLGQALMSLFVLASKDGWVDIMYDGLDAVGVDQQPIMNHNPWML--LYFISFLLIVAF 1503

Query: 497  MILSLFIALITDSYDTIKKFQQNGFPETDLQEFLKECSSKEEYQKESSAFLSC 549
             +L++F+ ++ +++   ++ Q+        ++ L+    K   +++  A   C
Sbjct: 1504 FVLNMFVGVVVENFHKCRQHQEEEEARRREEKRLRRLEKKRRSKEKQMAEAQC 1556


>gi|38505272 voltage-dependent calcium channel alpha 1G subunit
            isoform 9 [Homo sapiens]
          Length = 2273

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 21/113 (18%), Positives = 48/113 (42%), Gaps = 11/113 (9%)

Query: 446  FENLNTVAECLFSLVNGDDMFATFAQ------IQQKSIL---VWLFSRLYLYSFISLFIY 496
            F+NL      LF L + D              + Q+ I+    W+   LY  SF+ +  +
Sbjct: 1469 FDNLGQALMSLFVLASKDGWVDIMYDGLDAVGVDQQPIMNHNPWML--LYFISFLLIVAF 1526

Query: 497  MILSLFIALITDSYDTIKKFQQNGFPETDLQEFLKECSSKEEYQKESSAFLSC 549
             +L++F+ ++ +++   ++ Q+        ++ L+    K   +++  A   C
Sbjct: 1527 FVLNMFVGVVVENFHKCRQHQEEEEARRREEKRLRRLEKKRRSKEKQMAEAQC 1579


>gi|38505268 voltage-dependent calcium channel alpha 1G subunit
            isoform 14 [Homo sapiens]
          Length = 2171

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 21/113 (18%), Positives = 48/113 (42%), Gaps = 11/113 (9%)

Query: 446  FENLNTVAECLFSLVNGDDMFATFAQ------IQQKSIL---VWLFSRLYLYSFISLFIY 496
            F+NL      LF L + D              + Q+ I+    W+   LY  SF+ +  +
Sbjct: 1446 FDNLGQALMSLFVLASKDGWVDIMYDGLDAVGVDQQPIMNHNPWML--LYFISFLLIVAF 1503

Query: 497  MILSLFIALITDSYDTIKKFQQNGFPETDLQEFLKECSSKEEYQKESSAFLSC 549
             +L++F+ ++ +++   ++ Q+        ++ L+    K   +++  A   C
Sbjct: 1504 FVLNMFVGVVVENFHKCRQHQEEEEARRREEKRLRRLEKKRRSKEKQMAEAQC 1556


>gi|115583667 sodium channel, voltage-gated, type XI, alpha [Homo
            sapiens]
          Length = 1791

 Score = 30.8 bits (68), Expect = 3.5
 Identities = 38/226 (16%), Positives = 90/226 (39%), Gaps = 23/226 (10%)

Query: 339  QWEFINGWYVLVIISDLMTIIGSILKMEIKAKNLTNYDLCSIFLGTSTLLVWVGVIRYLG 398
            Q+ F NGW +   +  L++I+ +++      +N  +            L     ++R + 
Sbjct: 1422 QYYFTNGWNLFDCVVVLLSIVSTMIST---LENQEHIPFPPTLFRIVRLARIGRILRLVR 1478

Query: 399  YFQAYNVLILTMQASLPKVLRFCACAGMIYLGYTFCGWIVLGPYH-----DKFENLNTVA 453
              +    L+  +  SLP +        +I   Y   G       +     D   N  T A
Sbjct: 1479 AARGIRTLLFALMMSLPSLFNIGLLLFLIMFIYAILGMNWFSKVNPESGIDDIFNFKTFA 1538

Query: 454  E---CLFSLVNG---DDMFATFAQIQQ------KSILVWLFSRLYLYSFISLFIYMILSL 501
                CLF +      D + +   + ++      ++  +   +  Y  S+I +   +++++
Sbjct: 1539 SSMLCLFQISTSAGWDSLLSPMLRSKESCNSSSENCHLPGIATSYFVSYIIISFLIVVNM 1598

Query: 502  FIALITDSYDTIKKFQQNGFPETDLQEFLKECSSKEEYQKESSAFL 547
            +IA+I ++++T  +  ++   E D   F +     E++  E++ F+
Sbjct: 1599 YIAVILENFNTATEESEDPLGEDDFDIFYEVW---EKFDPEATQFI 1641


>gi|148612863 transient receptor potential cation channel, subfamily
           M, member 7 [Homo sapiens]
          Length = 1865

 Score = 29.6 bits (65), Expect = 7.7
 Identities = 14/62 (22%), Positives = 26/62 (41%)

Query: 363 LKMEIKAKNLTNYDLCSIFLGTSTLLVWVGVIRYLGYFQAYNVLILTMQASLPKVLRFCA 422
           +++++K+K L        F     +  W   + YLG+   Y  ++L     LP V  +  
Sbjct: 830 MEIQMKSKKLPITRKFYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQMEQLPSVQEWIV 889

Query: 423 CA 424
            A
Sbjct: 890 IA 891


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.141    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,044,108
Number of Sequences: 37866
Number of extensions: 838741
Number of successful extensions: 2669
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2626
Number of HSP's gapped (non-prelim): 32
length of query: 566
length of database: 18,247,518
effective HSP length: 108
effective length of query: 458
effective length of database: 14,157,990
effective search space: 6484359420
effective search space used: 6484359420
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.