Search of human proteins with 5454070

Search of human proteins with 5454070

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5454070 solute carrier family 9 (sodium/hydrogen exchanger),
member 6 isoform b [Homo sapiens]
         (669 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5454070 solute carrier family 9 (sodium/hydrogen exchanger), ...  1337   0.0  
gi|110227626 solute carrier family 9 (sodium/hydrogen exchanger)...  1321   0.0  
gi|14211919 solute carrier family 9, member 7 [Homo sapiens]          867   0.0  
gi|27734935 solute carrier family 9 (sodium/hydrogen exchanger),...   720   0.0  
gi|41872703 sodium/hydrogen exchanger 8 [Homo sapiens]                267   3e-71
gi|194239733 solute carrier family 9 (sodium/hydrogen exchanger)...   207   3e-53
gi|15529998 solute carrier family 9 (sodium/hydrogen exchanger),...   199   5e-51
gi|148727259 solute carrier family 9 (sodium/hydrogen exchanger)...   199   9e-51
gi|27777632 solute carrier family 9, isoform A1 [Homo sapiens]        190   3e-48
gi|4759144 solute carrier family 9 (sodium/hydrogen exchanger), ...   189   5e-48
gi|56786136 sperm-specific sodium proton exchanger [Homo sapiens]      50   7e-06
gi|52487176 tripartite motif-containing 37 protein [Homo sapiens]      35   0.17 
gi|15147333 tripartite motif-containing 37 protein [Homo sapiens]      35   0.17 
gi|54112420 Cas-Br-M (murine) ecotropic retroviral transforming ...    35   0.22 
gi|27734871 regulatory factor X, 6 [Homo sapiens]                      32   2.5  
gi|224465231 solute carrier family 9, member 11 [Homo sapiens]         32   2.5  
gi|13376856 solute carrier family 19, member 3 [Homo sapiens]          32   2.5  
gi|215820660 ATP-binding cassette, subfamily G, member 4 [Homo s...    31   3.2  
gi|20143975 ATP-binding cassette, subfamily G, member 4 [Homo sa...    31   3.2  
gi|164698502 septin 9 isoform d [Homo sapiens]                         31   4.2  
gi|148762940 DVL-binding protein DAPLE [Homo sapiens]                  30   5.5  
gi|4557373 biotinidase precursor [Homo sapiens]                        30   7.2  
gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]         30   7.2  
gi|46852164 mannosidase, alpha, class 2C, member 1 [Homo sapiens]      30   9.4  

>gi|5454070 solute carrier family 9 (sodium/hydrogen exchanger),
           member 6 isoform b [Homo sapiens]
          Length = 669

 Score = 1337 bits (3461), Expect = 0.0
 Identities = 669/669 (100%), Positives = 669/669 (100%)

Query: 1   MARRGWRRAPLRRGVGSSPRARRLMRPLWLLLAVGVFDWAGASDGGGGEARAMDEEIVSE 60
           MARRGWRRAPLRRGVGSSPRARRLMRPLWLLLAVGVFDWAGASDGGGGEARAMDEEIVSE
Sbjct: 1   MARRGWRRAPLRRGVGSSPRARRLMRPLWLLLAVGVFDWAGASDGGGGEARAMDEEIVSE 60

Query: 61  KQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGI 120
           KQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGI
Sbjct: 61  KQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGI 120

Query: 121 HVPSDVNNVTLSCEVQSSPTTLLVTFDPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSIL 180
           HVPSDVNNVTLSCEVQSSPTTLLVTFDPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSIL
Sbjct: 121 HVPSDVNNVTLSCEVQSSPTTLLVTFDPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSIL 180

Query: 181 AYAFLGTAISCFVIGSIMYGCVTLMKVTGQLAGDFYFTDCLLFGAIVSATDPVTVLAIFH 240
           AYAFLGTAISCFVIGSIMYGCVTLMKVTGQLAGDFYFTDCLLFGAIVSATDPVTVLAIFH
Sbjct: 181 AYAFLGTAISCFVIGSIMYGCVTLMKVTGQLAGDFYFTDCLLFGAIVSATDPVTVLAIFH 240

Query: 241 ELQVDVELYALLFGESVLNDAVAIVLSSSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFS 300
           ELQVDVELYALLFGESVLNDAVAIVLSSSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFS
Sbjct: 241 ELQVDVELYALLFGESVLNDAVAIVLSSSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFS 300

Query: 301 GSFAMGAATGVVTALVTKFTKLREFQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGI 360
           GSFAMGAATGVVTALVTKFTKLREFQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGI
Sbjct: 301 GSFAMGAATGVVTALVTKFTKLREFQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGI 360

Query: 361 TQAHYTYNNLSTESQHRTKQLFELLNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVA 420
           TQAHYTYNNLSTESQHRTKQLFELLNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVA
Sbjct: 361 TQAHYTYNNLSTESQHRTKQLFELLNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVA 420

Query: 421 IFLGRAANIYPLSLLLNLGRRSKIGSNFQHMMMFAGLRGAMAFALAIRDTATYARQMMFS 480
           IFLGRAANIYPLSLLLNLGRRSKIGSNFQHMMMFAGLRGAMAFALAIRDTATYARQMMFS
Sbjct: 421 IFLGRAANIYPLSLLLNLGRRSKIGSNFQHMMMFAGLRGAMAFALAIRDTATYARQMMFS 480

Query: 481 TTLLIVFFTVWVFGGGTTAMLSCLHIRVGVDSDQEHLGVPENERRTTKAESAWLFRMWYN 540
           TTLLIVFFTVWVFGGGTTAMLSCLHIRVGVDSDQEHLGVPENERRTTKAESAWLFRMWYN
Sbjct: 481 TTLLIVFFTVWVFGGGTTAMLSCLHIRVGVDSDQEHLGVPENERRTTKAESAWLFRMWYN 540

Query: 541 FDHNYLKPLLTHSGPPLTTTLPACCGPIARCLTSPQAYENQEQLKDDDSDLILNDGDISL 600
           FDHNYLKPLLTHSGPPLTTTLPACCGPIARCLTSPQAYENQEQLKDDDSDLILNDGDISL
Sbjct: 541 FDHNYLKPLLTHSGPPLTTTLPACCGPIARCLTSPQAYENQEQLKDDDSDLILNDGDISL 600

Query: 601 TYGDSTVNTEPATSSAPRRFMGNSSEDALDRELAFGDHELVIRGTRLVLPMDDSEPPLNL 660
           TYGDSTVNTEPATSSAPRRFMGNSSEDALDRELAFGDHELVIRGTRLVLPMDDSEPPLNL
Sbjct: 601 TYGDSTVNTEPATSSAPRRFMGNSSEDALDRELAFGDHELVIRGTRLVLPMDDSEPPLNL 660

Query: 661 LDNTRHGPA 669
           LDNTRHGPA
Sbjct: 661 LDNTRHGPA 669


>gi|110227626 solute carrier family 9 (sodium/hydrogen exchanger),
           member 6 isoform a [Homo sapiens]
          Length = 701

 Score = 1321 bits (3418), Expect = 0.0
 Identities = 669/701 (95%), Positives = 669/701 (95%), Gaps = 32/701 (4%)

Query: 1   MARRGWRRAPLRRGVGSSPRARRLMRPLWLLLAVGVFDWAGASDGGGGEARAMDEEIVSE 60
           MARRGWRRAPLRRGVGSSPRARRLMRPLWLLLAVGVFDWAGASDGGGGEARAMDEEIVSE
Sbjct: 1   MARRGWRRAPLRRGVGSSPRARRLMRPLWLLLAVGVFDWAGASDGGGGEARAMDEEIVSE 60

Query: 61  KQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGI 120
           KQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGI
Sbjct: 61  KQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGI 120

Query: 121 HVPSDVNNVTLSCEVQSSPTTLLV--------------------------------TFDP 148
           HVPSDVNNVTLSCEVQSSPTTLLV                                TFDP
Sbjct: 121 HVPSDVNNVTLSCEVQSSPTTLLVNVSGKFYEYMLKGEISSHELNNVQDNEMLRKVTFDP 180

Query: 149 EVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVT 208
           EVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVT
Sbjct: 181 EVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVT 240

Query: 209 GQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSS 268
           GQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSS
Sbjct: 241 GQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSS 300

Query: 269 SIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLL 328
           SIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLL
Sbjct: 301 SIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLL 360

Query: 329 ETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFL 388
           ETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFL
Sbjct: 361 ETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFL 420

Query: 389 AENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKIGSNF 448
           AENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKIGSNF
Sbjct: 421 AENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKIGSNF 480

Query: 449 QHMMMFAGLRGAMAFALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTAMLSCLHIRV 508
           QHMMMFAGLRGAMAFALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTAMLSCLHIRV
Sbjct: 481 QHMMMFAGLRGAMAFALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTAMLSCLHIRV 540

Query: 509 GVDSDQEHLGVPENERRTTKAESAWLFRMWYNFDHNYLKPLLTHSGPPLTTTLPACCGPI 568
           GVDSDQEHLGVPENERRTTKAESAWLFRMWYNFDHNYLKPLLTHSGPPLTTTLPACCGPI
Sbjct: 541 GVDSDQEHLGVPENERRTTKAESAWLFRMWYNFDHNYLKPLLTHSGPPLTTTLPACCGPI 600

Query: 569 ARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTEPATSSAPRRFMGNSSEDA 628
           ARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTEPATSSAPRRFMGNSSEDA
Sbjct: 601 ARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTEPATSSAPRRFMGNSSEDA 660

Query: 629 LDRELAFGDHELVIRGTRLVLPMDDSEPPLNLLDNTRHGPA 669
           LDRELAFGDHELVIRGTRLVLPMDDSEPPLNLLDNTRHGPA
Sbjct: 661 LDRELAFGDHELVIRGTRLVLPMDDSEPPLNLLDNTRHGPA 701


>gi|14211919 solute carrier family 9, member 7 [Homo sapiens]
          Length = 725

 Score =  867 bits (2239), Expect = 0.0
 Identities = 465/710 (65%), Positives = 533/710 (75%), Gaps = 75/710 (10%)

Query: 18  SPRARRLMRPLWLLLAVGVFDWAGASDGGGG-EARAMDEEIVSEKQAEESHRQDSANLLI 76
           +P  R L+ PL L   + V   A AS  G   E  +  EE+ +EK+AEESHRQDS +LL 
Sbjct: 17  APPPRLLLLPLLLGWGLRVAAAASASSSGAAAEDSSAMEELATEKEAEESHRQDSVSLLT 76

Query: 77  FILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGIHVPSDVNNVTLSCEVQ 136
           FILLLTLTILTIWLFKHRR RFLHETGLAMIYGL+VG++LRYG    S   + +LSC  +
Sbjct: 77  FILLLTLTILTIWLFKHRRVRFLHETGLAMIYGLIVGVILRYGTPATSG-RDKSLSCTQE 135

Query: 137 SSP-TTLLV--------------------------------TFDPEVFFNILLPPIIFYA 163
               +TLLV                                TFDPEVFFNILLPPIIF+A
Sbjct: 136 DRAFSTLLVNVSGKFFEYTLKGEISPGKINSVEQNDMLRKVTFDPEVFFNILLPPIIFHA 195

Query: 164 GYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVTGQLAGDFYFTDCLLF 223
           GYSLK+RHFFRNLGSILAYAFLGTA+SCF+IG++MYG V LMK+ GQL+  FY+TDCL F
Sbjct: 196 GYSLKKRHFFRNLGSILAYAFLGTAVSCFIIGNLMYGVVKLMKIMGQLSDKFYYTDCLFF 255

Query: 224 GAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSSSIVAYQPAGDNSHTF 283
           GAI+SATDPVTVLAIF+EL  DV+LYALLFGESVLNDAVAIVLSSSIVAYQPAG N+H F
Sbjct: 256 GAIISATDPVTVLAIFNELHADVDLYALLFGESVLNDAVAIVLSSSIVAYQPAGLNTHAF 315

Query: 284 DVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLLETGLFFLMSWSTFLL 343
           D  A FKS+GIFLGIFSGSF MGA TGV  A VTKFTKL  F LLET LFFLMSWSTFLL
Sbjct: 316 DAAAFFKSVGIFLGIFSGSFTMGAVTGV-NANVTKFTKLHCFPLLETALFFLMSWSTFLL 374

Query: 344 AEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFLAENFIFSYMGLTLFT 403
           AEA GFTGVVAVLFCGITQAHYTYNNLS ES+ RTKQLFE+L+FLAENFIFSYMGL LFT
Sbjct: 375 AEACGFTGVVAVLFCGITQAHYTYNNLSVESRSRTKQLFEVLHFLAENFIFSYMGLALFT 434

Query: 404 FQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKIGSNFQHMMMFAGLRGAMAF 463
           FQ HVF+P F++GAFVAIFLGRAA+IYPLS  LNLGRR KIG NFQHMMMF+GLRGAMAF
Sbjct: 435 FQKHVFSPIFIIGAFVAIFLGRAAHIYPLSFFLNLGRRHKIGWNFQHMMMFSGLRGAMAF 494

Query: 464 ALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTAMLSCLHIRVGVDSDQEH------- 516
           ALAIRDTA+YARQMMF+TTLLIVFFTVW+ GGGTT MLS L+IRVGV+   E        
Sbjct: 495 ALAIRDTASYARQMMFTTTLLIVFFTVWIIGGGTTPMLSWLNIRVGVEEPSEEDQNEHHW 554

Query: 517 ----LGV--------------------PENER-RTTKAESAWLFRMWYNFDHNYLKPLLT 551
               +GV                    P++ R   TK ESAW+FR+WY+FDHNYLKP+LT
Sbjct: 555 QYFRVGVDPDQDPPPNNDSFQVLQGDGPDSARGNRTKQESAWIFRLWYSFDHNYLKPILT 614

Query: 552 HSGPPLTTTLPACCGPIARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTEP 611
           HSGPPLTTTLPA CG +ARCLTSPQ Y+NQE L+++DSD IL +GD++LTYGDSTV    
Sbjct: 615 HSGPPLTTTLPAWCGLLARCLTSPQVYDNQEPLREEDSDFILTEGDLTLTYGDSTVTANG 674

Query: 612 ATSS-------APRRFMGNSSEDALDRELAFGDHELVIRGTRLVLPMDDS 654
           ++SS          R   +SSE+ L+R+L  GD ++  RGTRLV P++D+
Sbjct: 675 SSSSHTASTSLEGSRRTKSSSEEVLERDLGMGDQKVSSRGTRLVFPLEDN 724


>gi|27734935 solute carrier family 9 (sodium/hydrogen exchanger),
           member 9 [Homo sapiens]
          Length = 645

 Score =  720 bits (1859), Expect = 0.0
 Identities = 382/636 (60%), Positives = 466/636 (73%), Gaps = 51/636 (8%)

Query: 57  IVSEKQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVL 116
           ++SEK   +   Q +  LL+F  LL LTILTIWLFK+ R RFLHETG AM+YGL++GL+L
Sbjct: 7   VMSEKDEYQFQHQGAVELLVFNFLLILTILTIWLFKNHRFRFLHETGGAMVYGLIMGLIL 66

Query: 117 RYGIHVPSDVNNVTL--SCEVQSSPTTLLV------------------------------ 144
           RY    P+D+ + T+    ++  SP+TLLV                              
Sbjct: 67  RYAT-APTDIESGTVYDCVKLTFSPSTLLVNITDQVYEYKYKREISQHNINPHQGNAILE 125

Query: 145 --TFDPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCV 202
             TFDPE+FFN+LLPPIIF+AGYSLK+RHFF+NLGSIL YAFLGTAISC VIG IMYG V
Sbjct: 126 KMTFDPEIFFNVLLPPIIFHAGYSLKKRHFFQNLGSILTYAFLGTAISCIVIGLIMYGFV 185

Query: 203 TLMKVTGQLA-GDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDA 261
             M   GQL  GDF+FTDCL FG+++SATDPVTVLAIFHEL VD +LY LLFGESVLNDA
Sbjct: 186 KAMIHAGQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDA 245

Query: 262 VAIVLSSSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTK 321
           VAIVL+ SI  Y P  +N + FD  A F+S+G FLGIF+GSFAMG+A  ++TAL+TKFTK
Sbjct: 246 VAIVLTYSISIYSPK-ENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLTKFTK 304

Query: 322 LREFQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQL 381
           L EF +LETGLFFL+SWS FL AEA G TG+VAVLFCG+TQAHYTYNNLS++S+ RTKQL
Sbjct: 305 LCEFPMLETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDSKIRTKQL 364

Query: 382 FELLNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRR 441
           FE +NFLAEN IF YMGL LFTFQNH+FN  F++GAF+AIF+ RA NIYPLS LLNLGR+
Sbjct: 365 FEFMNFLAENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLNLGRK 424

Query: 442 SKIGSNFQHMMMFAGLRGAMAFALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTAML 501
            KI  NFQHMMMF+GLRGA+AFALAIR+T +  +QMMF+TTLL+VFFTVWVFGGGTT ML
Sbjct: 425 QKIPWNFQHMMMFSGLRGAIAFALAIRNTESQPKQMMFTTTLLLVFFTVWVFGGGTTPML 484

Query: 502 SCLHIRVGVDSDQ--------EHLGVPENERRTTKAESAWLFRMWYNFDHNYLKPLLTHS 553
           + L IRVGVD D+        +H      ++  TKAESA LFRMWY+FDH YLKP+LTHS
Sbjct: 485 TWLQIRVGVDLDENLKEDPSSQHQEANNLDKNMTKAESARLFRMWYSFDHKYLKPILTHS 544

Query: 554 GPPLTTTLPACCGPIARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGD--STVNTEP 611
           GPPLTTTLP  CGPI+R LTSPQAY   EQLK+DD + I+N  ++++ Y +  S+  + P
Sbjct: 545 GPPLTTTLPEWCGPISRLLTSPQAY--GEQLKEDDVECIVNQDELAINYQEQASSPCSPP 602

Query: 612 ATSSAPRRFMGNS--SEDALDRELAFGDHELVIRGT 645
           A     ++    +   E+  + +L  G +EL +  T
Sbjct: 603 ARLGLDQKASPQTPGKENIYEGDLGLGGYELKLEQT 638


>gi|41872703 sodium/hydrogen exchanger 8 [Homo sapiens]
          Length = 581

 Score =  267 bits (682), Expect = 3e-71
 Identities = 161/450 (35%), Positives = 254/450 (56%), Gaps = 26/450 (5%)

Query: 61  KQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGI 120
           +QA++  +     +   +L+L + I+ + L    R  FL E+   +  G+L+G V++   
Sbjct: 49  EQAQQEEQSSGMTIFFSLLVLAICIILVHLLIRYRLHFLPESVAVVSLGILMGAVIKI-- 106

Query: 121 HVPSDVNNVTLSCEVQSSPTTLLVTFDPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSIL 180
                +    L+   +         F P +FF +LLPPIIF +GYSL + +FF+N+GSI 
Sbjct: 107 -----IEFKKLANWKEEE------MFRPNMFFLLLLPPIIFESGYSLHKGNFFQNIGSIT 155

Query: 181 AYAFLGTAISCFVIGSIMYGCVTLMKVTGQ--LAGDFYFTDCLLFGAIVSATDPVTVLAI 238
            +A  GTAIS FV+G  +Y         GQ  +      TD   FG+++SA DPV  +AI
Sbjct: 156 LFAVFGTAISAFVVGGGIY-------FLGQADVISKLNMTDSFAFGSLISAVDPVATIAI 208

Query: 239 FHELQVDVELYALLFGESVLNDAVAIVLSSSIVAYQPAGDNSHTFDVTAMFKSIGIFLGI 298
           F+ L VD  L  L+FGES+LNDAV+IVL+++        + S         +++  FL +
Sbjct: 209 FNALHVDPVLNMLVFGESILNDAVSIVLTNTAEGLTRK-NMSDVSGWQTFLQALDYFLKM 267

Query: 299 FSGSFAMGAATGVVTALVTKFTKLREFQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFC 358
           F GS A+G  TG+++ALV K   LR+   LE G+  + ++  + LAE    +G++A+LF 
Sbjct: 268 FFGSAALGTLTGLISALVLKHIDLRKTPSLEFGMMIIFAYLPYGLAEGISLSGIMAILFS 327

Query: 359 GITQAHYTYNNLSTESQHRTKQLFELLNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAF 418
           GI  +HYT++NLS  +Q   +Q    + FL E  +F+++GL++F+F  H F  +FV+   
Sbjct: 328 GIVMSHYTHHNLSPVTQILMQQTLRTVAFLCETCVFAFLGLSIFSFP-HKFEISFVIWCI 386

Query: 419 VAIFLGRAANIYPLSLLLNLGRRSKIGSNFQHMMMFAGLRGAMAFALAIR--DTATYARQ 476
           V +  GRA NI+PLS LLN  R  KI      +M F+GLRGA+ +AL++         RQ
Sbjct: 387 VLVLFGRAVNIFPLSYLLNFFRDHKITPKMMFIMWFSGLRGAIPYALSLHLDLEPMEKRQ 446

Query: 477 MMFSTTLLIVFFTVWVFGGGTTAMLSCLHI 506
           ++ +TT++IV FT+ + GG T  ++  + I
Sbjct: 447 LIGTTTIVIVLFTILLLGGSTMPLIRLMDI 476


>gi|194239733 solute carrier family 9 (sodium/hydrogen exchanger),
           isoform 3 [Homo sapiens]
          Length = 834

 Score =  207 bits (526), Expect = 3e-53
 Identities = 156/482 (32%), Positives = 246/482 (51%), Gaps = 37/482 (7%)

Query: 21  ARRLMRPLWLLLAVGVFDWAGASD--GGGGEARAMDEEIVSEKQAEESHRQDSANLLIFI 78
           AR   R L L LA+G    AG  +   GG    +   ++V+    E +H QD   + ++I
Sbjct: 6   ARGPDRGLLLALALGGLARAGGVEVEPGGAHGESGGFQVVT---FEWAHVQDPYVIALWI 62

Query: 79  LLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGIHVPSDVNNVTLSCEVQSS 138
           L+ +L  +   L  H+    + E+ L ++ GL++G ++    H+ S              
Sbjct: 63  LVASLAKIGFHL-SHKVTSVVPESALLIVLGLVLGGIVWAADHIAS-------------- 107

Query: 139 PTTLLVTFDPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIM 198
                 T  P VFF  LLPPI+  AGY +  R FF NLG+IL YA +GT  +    G  +
Sbjct: 108 -----FTLTPTVFFFYLLPPIVLDAGYFMPNRLFFGNLGTILLYAVVGTVWNAATTGLSL 162

Query: 199 YGCVTLMKVTGQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVL 258
           YG V L  + G L       D LLFG++++A DPV VLA+F E+ V+  L+ ++FGES+L
Sbjct: 163 YG-VFLSGLMGDL--QIGLLDFLLFGSLMAAVDPVAVLAVFEEVHVNEVLFIIVFGESLL 219

Query: 259 NDAVAIVLSSSIVAYQP-AGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVT 317
           NDAV +VL +   ++    GDN    D     K I  F  +  G   +G     + +LVT
Sbjct: 220 NDAVTVVLYNVFESFVALGGDNVTGVDCV---KGIVSFFVVSLGGTLVGVVFAFLLSLVT 276

Query: 318 KFTKLREFQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHR 377
           +FTK    +++E G  F++S+ ++L +E    + ++A+ FCGI    Y   N+S +S   
Sbjct: 277 RFTK--HVRIIEPGFVFIISYLSYLTSEMLSLSAILAITFCGICCQKYVKANISEQSATT 334

Query: 378 TKQLFELLNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLN 437
            +   ++L   AE  IF ++G++        +N  FV+   V I + RA  +   + LLN
Sbjct: 335 VRYTMKMLASSAETIIFMFLGISAVNPFIWTWNTAFVLLTLVFISVYRAIGVVLQTWLLN 394

Query: 438 LGRRSKIGSNFQHMMMFAGLRGAMAFALAI--RDTATYARQMMFSTTLLIVFFTVWVFGG 495
             R  ++    Q ++ + GLRGA+AFAL +         + +  STT+++VFFTV +F G
Sbjct: 395 RYRMVQLEPIDQVVLSYGGLRGAVAFALVVLLDGDKVKEKNLFVSTTIIVVFFTV-IFQG 453

Query: 496 GT 497
            T
Sbjct: 454 LT 455


>gi|15529998 solute carrier family 9 (sodium/hydrogen exchanger),
           member 2 [Homo sapiens]
          Length = 812

 Score =  199 bits (507), Expect = 5e-51
 Identities = 145/505 (28%), Positives = 250/505 (49%), Gaps = 48/505 (9%)

Query: 67  HRQDSANLLIFILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGIHVPSDV 126
           H Q    + ++ILL +L  +   L+ H+    + E+ L ++ GLL+G ++ +G+      
Sbjct: 77  HVQIPFEITLWILLASLAKIGFHLY-HKLPTIVPESCLLIMVGLLLGGII-FGVD----- 129

Query: 127 NNVTLSCEVQSSPTTLLVTFDPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLG 186
                    + SP  +      +VFF  LLPPI+  AGY +  R FF N+G+I  YA +G
Sbjct: 130 ---------EKSPPAMKT----DVFFLYLLPPIVLDAGYFMPTRPFFENIGTIFWYAVVG 176

Query: 187 TAISCFVIGSIMYGCVTLMKVTGQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDV 246
           T  +   IG  ++G   + ++      D      LLFG+++SA DPV VLA+F  + V+ 
Sbjct: 177 TLWNSIGIGVSLFG---ICQIEAFGLSDITLLQNLLFGSLISAVDPVAVLAVFENIHVNE 233

Query: 247 ELYALLFGESVLNDAVAIVLSSSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMG 306
           +LY L+FGES+LNDAV +VL +   ++        T +   +F  I  F  +  G   +G
Sbjct: 234 QLYILVFGESLLNDAVTVVLYNLFKSF----CQMKTIETIDVFAGIANFFVVGIGGVLIG 289

Query: 307 AATGVVTALVTKFTKLREFQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYT 366
              G + A  T+FT     +++E    FL S+ +++ AE +  +G++A+  C +T   Y 
Sbjct: 290 IFLGFIAAFTTRFT--HNIRVIEPLFVFLYSYLSYITAEMFHLSGIMAITACAMTMNKYV 347

Query: 367 YNNLSTESQHRTKQLFELLNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRA 426
             N+S +S    K   ++L+ ++E  IF +MG++    +NH +N  FV        + RA
Sbjct: 348 EENVSQKSYTTIKYFMKMLSSVSETLIFIFMGVST-VGKNHEWNWAFVCFTLAFCLMWRA 406

Query: 427 ANIYPLSLLLNLGRRSKIGSNFQHMMMFAGLRGAMAFALA-IRDTATYARQMMFST-TLL 484
             ++ L+ ++N  R   +    Q ++ + GLRGA+ FAL  +   A + R+ +F T  ++
Sbjct: 407 LGVFVLTQVINRFRTIPLTFKDQFIIAYGGLRGAICFALVFLLPAAVFPRKKLFITAAIV 466

Query: 485 IVFFTVWVFGGGTTAMLSCLHIRVGVDSDQEHLGVPEN------ERRTTKAESA---WLF 535
           ++FFTV++ G     ++  L ++    S+++   V E       +   T  E     W  
Sbjct: 467 VIFFTVFILGITIRPLVEFLDVK---RSNKKQQAVSEEIYCRLFDHVKTGIEDVCGHWGH 523

Query: 536 RMWYN----FDHNYLKPLLTHSGPP 556
             W +    FD  YL+ LL     P
Sbjct: 524 NFWRDKFKKFDDKYLRKLLIRENQP 548


>gi|148727259 solute carrier family 9 (sodium/hydrogen exchanger),
           member 4 [Homo sapiens]
          Length = 798

 Score =  199 bits (505), Expect = 9e-51
 Identities = 151/528 (28%), Positives = 262/528 (49%), Gaps = 42/528 (7%)

Query: 42  ASDGGGGEARAMDEEIVSEKQAEESHRQDSANLLIFILLLTLTILTIWLFKHRRARFLHE 101
           AS+     A +  EE +S  + +  + Q    + ++ILL +L  +   L+ HR    + E
Sbjct: 41  ASNAWFAAASSEPEEGISVFELDYDYVQIPYEVTLWILLASLAKIGFHLY-HRLPGLMPE 99

Query: 102 TGLAMIYGLLVGLVLRYGIHVPSDVNNVTLSCEVQSSPTTLLVTFDPEVFFNILLPPIIF 161
           + L ++ G LVG     GI   +D            SP  +    D  ++F  LLPPI+ 
Sbjct: 100 SCLLILVGALVG-----GIIFGTD----------HKSPPVM----DSSIYFLYLLPPIVL 140

Query: 162 YAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVTGQLAGDFYFTDCL 221
             GY +  R FF N+GSIL +A LG  I+   IG  +Y  +  +K  G   GD      L
Sbjct: 141 EGGYFMPTRPFFENIGSILWWAVLGALINALGIGLSLY-LICQVKAFG--LGDVNLLQNL 197

Query: 222 LFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSSSIVAYQPAG--DN 279
           LFG+++SA DPV VLA+F E +V+ +LY ++FGE++LND + +VL + ++A+      ++
Sbjct: 198 LFGSLISAVDPVAVLAVFEEARVNEQLYMMIFGEALLNDGITVVLYNMLIAFTKMHKFED 257

Query: 280 SHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLLETGLFFLMSWS 339
             T D+ A       F+ +  G    G   G ++A +T+FT  +    +E  + F+ S+ 
Sbjct: 258 IETVDILA---GCARFIVVGLGGVLFGIVFGFISAFITRFT--QNISAIEPLIVFMFSYL 312

Query: 340 TFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFLAENFIFSYMGL 399
           ++L AE    +G++A+  C +T   Y   N+S  S    K   ++L+ ++E  IF +MG+
Sbjct: 313 SYLAAETLYLSGILAITACAVTMKKYVEENVSQTSYTTIKYFMKMLSSVSETLIFIFMGV 372

Query: 400 TLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKIGSNFQHMMMFAGLRG 459
           +    +NH +N  F+        + RA +++ L  + N  R        Q ++ ++G+RG
Sbjct: 373 ST-VGKNHEWNWAFICFTLAFCQIWRAISVFALFYISNQFRTFPFSIKDQCIIFYSGVRG 431

Query: 460 AMAFALA-IRDTATYARQMMFST-TLLIVFFTVWVFGGGTTAMLSCLHIRV--GVDSDQE 515
           A +F+LA +   + + R+ MF T TL++++FTV++ G     ++  L ++     +S  E
Sbjct: 432 AGSFSLAFLLPLSLFPRKKMFVTATLVVIYFTVFIQGITVGPLVRYLDVKKTNKKESINE 491

Query: 516 HLGVPENERRTTKAESA---W----LFRMWYNFDHNYLKPLLTHSGPP 556
            L +   +      E     W    +   +  FDH YL+ +L     P
Sbjct: 492 ELHIRLMDHLKAGIEDVCGHWSHYQVRDKFKKFDHRYLRKILIRKNLP 539


>gi|27777632 solute carrier family 9, isoform A1 [Homo sapiens]
          Length = 815

 Score =  190 bits (483), Expect = 3e-48
 Identities = 122/370 (32%), Positives = 199/370 (53%), Gaps = 30/370 (8%)

Query: 149 EVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVT 208
           +VFF  LLPPII  AGY L  R F  NLG+IL +A +GT  + F +G +MY    +  V 
Sbjct: 159 DVFFLFLLPPIILDAGYFLPLRQFTENLGTILIFAVVGTLWNAFFLGGLMYA---VCLVG 215

Query: 209 GQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSS 268
           G+   +    D LLFG+I+SA DPV VLA+F E+ ++  L+ L+FGES+LNDAV +VL  
Sbjct: 216 GEQINNIGLLDNLLFGSIISAVDPVAVLAVFEEIHINELLHILVFGESLLNDAVTVVL-- 273

Query: 269 SIVAYQPAGDNSHTFDVTAMFKSIG---IFLGIFS------GSFAMGAATGVVTALVTKF 319
                       H F+  A ++ +G   IFLG  S      G   +G   GV+ A  ++F
Sbjct: 274 -----------YHLFEEFANYEHVGIVDIFLGFLSFFVVALGGVLVGVVYGVIAAFTSRF 322

Query: 320 TKLREFQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTK 379
           T     +++E    FL S+  +L AE +  +G++A++  G+    Y   N+S +S    K
Sbjct: 323 TS--HIRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASGVVMRPYVEANISHKSHTTIK 380

Query: 380 QLFELLNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLG 439
              ++ + ++E  IF ++G++     +H +N TFV+   +   + R   +  L+  +N  
Sbjct: 381 YFLKMWSSVSETLIFIFLGVSTVAGSHH-WNWTFVISTLLFCLIARVLGVLGLTWFINKF 439

Query: 440 RRSKIGSNFQHMMMFAGLRGAMAFALA-IRDTATYARQMMFSTTLL-IVFFTVWVFGGGT 497
           R  K+    Q ++ + GLRGA+AF+L  + D   +    +F T ++ ++FFTV+V G   
Sbjct: 440 RIVKLTPKDQFIIAYGGLRGAIAFSLGYLLDKKHFPMCDLFLTAIITVIFFTVFVQGMTI 499

Query: 498 TAMLSCLHIR 507
             ++  L ++
Sbjct: 500 RPLVDLLAVK 509


>gi|4759144 solute carrier family 9 (sodium/hydrogen exchanger),
           isoform 5 [Homo sapiens]
          Length = 896

 Score =  189 bits (481), Expect = 5e-48
 Identities = 120/350 (34%), Positives = 185/350 (52%), Gaps = 8/350 (2%)

Query: 147 DPEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMK 206
           +P  FF  LLPPI+  +GY +  R FF NLG+IL YA +GT  + F  G+ ++G      
Sbjct: 103 EPGTFFLFLLPPIVLDSGYFMPSRLFFDNLGAILTYAVVGTLWNAFTTGAALWGLQQAGL 162

Query: 207 VTGQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVL 266
           V  ++       D LLFG+++SA DPV VLA+F E+ V+  L+ ++FGES+LNDAV +VL
Sbjct: 163 VAPRVQAGLL--DFLLFGSLISAVDPVAVLAVFEEVHVNETLFIIVFGESLLNDAVTVVL 220

Query: 267 SSSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQ 326
                ++   G  S     T   K +     +  G  A+G     + AL T+FTK    +
Sbjct: 221 YKVCNSFVEMG--SANVQATDYLKGVASLFVVSLGGAAVGLVFAFLLALTTRFTK--RVR 276

Query: 327 LLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLN 386
           ++E  L FL++++ +L AE    + ++AV  CG+    Y   N+S +S+   K   + L 
Sbjct: 277 IIEPLLVFLLAYAAYLTAEMASLSAILAVTMCGLGCKKYVEANISHKSRTTVKYTMKTLA 336

Query: 387 FLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSLLLNLGRRSKIGS 446
             AE  IF  +G++        ++   V+G  + I   RA  +   + +LN  R   +  
Sbjct: 337 SCAETVIFMLLGISAVDSSKWAWDSGLVLGTLIFILFFRALGVVLQTWVLNQFRLVPLDK 396

Query: 447 NFQHMMMFAGLRGAMAFALAI--RDTATYARQMMFSTTLLIVFFTVWVFG 494
             Q +M + GLRGA+AFAL I    T   A+    +TT+++VFFTV V G
Sbjct: 397 IDQVVMSYGGLRGAVAFALVILLDRTKVPAKDYFVATTIVVVFFTVIVQG 446


>gi|56786136 sperm-specific sodium proton exchanger [Homo sapiens]
          Length = 1177

 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 66/319 (20%), Positives = 128/319 (40%), Gaps = 41/319 (12%)

Query: 148 PEVFFNILLPPIIFYAGYSLKRRHFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKV 207
           P++FF I  P + F   + +      +    IL  +  G  ++  ++   +     L+  
Sbjct: 76  PDLFFRIFTPVVFFTTAFDMDTYMLQKLFWQILLISIPGFLVNYILVLWHLASVNQLLLK 135

Query: 208 TGQLAGDFYFTDCLLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLS 267
                     T  LLF AI+ ++DP+   A   +L +   L +L+ GES++   ++++  
Sbjct: 136 P---------TQWLLFSAILVSSDPMLTAAAIRDLGLSRSLISLINGESLMTSVISLITF 186

Query: 268 SSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREF-- 325
           +SI+ +     +      T   + +G        SF      G++++ + +F     F  
Sbjct: 187 TSIMDFDQRLQSKRNH--TLAEEIVGGICSYIIASFLF----GILSSKLIQFWMSTVFGD 240

Query: 326 QLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELL 385
            +    L F + +  F + E  G +G+  +   G+       N+ S ++      L E  
Sbjct: 241 DVNHISLIFSILYLIFYICELVGMSGIFTLAIVGL-----LLNSTSFKAAIEETLLLEFW 295

Query: 386 NFL---AENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYP-------LSLL 435
            FL   A   +F++ GL +          T++   FV I+   + NIY        L+LL
Sbjct: 296 TFLSRIAFLMVFTFFGLLIPAH-------TYLYIEFVDIYY--SLNIYLTLIVLRFLTLL 346

Query: 436 LNLGRRSKIGSNFQHMMMF 454
           L     S++G  F    +F
Sbjct: 347 LISPVLSRVGHEFSWRWIF 365


>gi|52487176 tripartite motif-containing 37 protein [Homo sapiens]
          Length = 964

 Score = 35.4 bits (80), Expect = 0.17
 Identities = 18/64 (28%), Positives = 37/64 (57%), Gaps = 2/64 (3%)

Query: 579 ENQEQLKDDDSDLILNDGDIS--LTYGDSTVNTEPATSSAPRRFMGNSSEDALDRELAFG 636
           E++E+++++D    L+DGD+   L Y D     + ++SSA      N+ E+ +D E   G
Sbjct: 499 EDEEKIQNEDYHHELSDGDLDLDLVYEDEVNQLDGSSSSASSTATSNTEENDIDEETMSG 558

Query: 637 DHEL 640
           ++++
Sbjct: 559 ENDV 562


>gi|15147333 tripartite motif-containing 37 protein [Homo sapiens]
          Length = 964

 Score = 35.4 bits (80), Expect = 0.17
 Identities = 18/64 (28%), Positives = 37/64 (57%), Gaps = 2/64 (3%)

Query: 579 ENQEQLKDDDSDLILNDGDIS--LTYGDSTVNTEPATSSAPRRFMGNSSEDALDRELAFG 636
           E++E+++++D    L+DGD+   L Y D     + ++SSA      N+ E+ +D E   G
Sbjct: 499 EDEEKIQNEDYHHELSDGDLDLDLVYEDEVNQLDGSSSSASSTATSNTEENDIDEETMSG 558

Query: 637 DHEL 640
           ++++
Sbjct: 559 ENDV 562


>gi|54112420 Cas-Br-M (murine) ecotropic retroviral transforming
           sequence b [Homo sapiens]
          Length = 982

 Score = 35.0 bits (79), Expect = 0.22
 Identities = 42/173 (24%), Positives = 69/173 (39%), Gaps = 19/173 (10%)

Query: 505 HIRVGVDSDQEHLGVPENERRTTKAESAWLFRMWYNFDHNYLKPLLTHSGPPLTTTLPA- 563
           H RVG D     + + ++ R     E A +F   +     Y  P      PP+TT LP+ 
Sbjct: 629 HSRVGSDP----VLMRKHRRHDLPLEGAKVFSNGHLGSEEYDVPPRLSPPPPVTTLLPSI 684

Query: 564 -CCGPIARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTV-NTEPATSSAPRR-- 619
            C GP+A  L+       +E   DDD   I +   +SL    S   N +P   S      
Sbjct: 685 KCTGPLANSLSEKTRDPVEE---DDDEYKIPSSHPVSLNSQPSHCHNVKPPVRSCDNGHC 741

Query: 620 FMGNSSEDALDRELAFGDHELVIRGTRL-----VLPMDDSEPPLNLLDNTRHG 667
            +  +   + +++    D  + ++G         +P+  + PP    DN +HG
Sbjct: 742 MLNGTHGPSSEKKSNIPDLSIYLKGDVFDSASDPVPLPPARPPTR--DNPKHG 792


>gi|27734871 regulatory factor X, 6 [Homo sapiens]
          Length = 928

 Score = 31.6 bits (70), Expect = 2.5
 Identities = 23/94 (24%), Positives = 38/94 (40%), Gaps = 4/94 (4%)

Query: 575 PQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTEPAT--SSAPRRFMGNSSEDALDRE 632
           P +Y    Q +D  +   LN G  +        + + AT   ++P  + G++        
Sbjct: 754 PSSYGPSLQAQDSHNMQFLNTGSFNFLSNTGAASCQGATLPPNSPNGYYGSNINYPESHR 813

Query: 633 LA--FGDHELVIRGTRLVLPMDDSEPPLNLLDNT 664
           L      H  VI   R + P  D   PLN+LD++
Sbjct: 814 LGSMVNQHVSVISSIRSLPPYSDIHDPLNILDDS 847


>gi|224465231 solute carrier family 9, member 11 [Homo sapiens]
          Length = 1124

 Score = 31.6 bits (70), Expect = 2.5
 Identities = 57/294 (19%), Positives = 115/294 (39%), Gaps = 36/294 (12%)

Query: 111 LVGLVLRYGIHVPSDVNNVTLSCEVQSSPTTLLVTFDPEVFFNILLPPIIFYAGYSLKRR 170
           L G V+ +  +   +V+ +     +++S  +L   F P + F + L        Y+LK+ 
Sbjct: 62  LSGFVIGHMAYNSVEVHQIVYPL-LRTSSFSLYSYFSPLIIFMVALDVEF----YTLKK- 115

Query: 171 HFFRNLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVTGQLAGDFY-FTDCLLFGAIVSA 229
                    + +  L T +  F   SI+ G V +     +   D +    CLLF   +  
Sbjct: 116 ---------MFWQVLLTGLISFSTASIIIGYVVI-----KFNKDSWDLQSCLLFSITLGI 161

Query: 230 TDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSSSIVAYQPAGDNSHTFDVTAMF 289
            DP+  +     + +      L+ GES++  ++A +   +       G+  H      + 
Sbjct: 162 IDPLRSVNSLKTIGISKIYIDLIRGESLIICSIASIFFGNF-----RGNRIHFSIFRDLH 216

Query: 290 KSIGIFLGIFSGSFAMG--AATGVVTALVTKFTKLREFQLLETGLFFLMSWSTFLLAEAW 347
             I +   I  GS   G   A  +   L   F+ +    L    L F M + TF + E  
Sbjct: 217 VGIELSYDIL-GSIIFGYWCAKIIQCILADVFSNM----LTNIILCFSMVYMTFYIVEFL 271

Query: 348 GFTGVVAVLFCGITQAHYTYNNLSTESQHRTKQLFELLNFLAENFIFSYMGLTL 401
           G +G +A+   G+     T+     + +    +   + + + E+ I+++ G+ +
Sbjct: 272 GMSGTLALAAVGLNLDSLTF---KPKIELVITKFLRIFSSVYEHLIYAFFGIVI 322


>gi|13376856 solute carrier family 19, member 3 [Homo sapiens]
          Length = 496

 Score = 31.6 bits (70), Expect = 2.5
 Identities = 33/147 (22%), Positives = 64/147 (43%), Gaps = 26/147 (17%)

Query: 177 GSILAYAFLGTAISCFVIGSI-----MYGCVTLMKVTGQLAGDFY-----------FTDC 220
           G++ A A  G A++ F +G +     + G + L+  +   AG  +           +   
Sbjct: 317 GAVEAIATFGGAVAAFAVGYVKVNWDLLGELALVVFSVVNAGSLFLMHYTANIWACYAGY 376

Query: 221 LLFGAIVSATDPVTVLAIFHELQVDVELYALLFGESVLNDAVAIVLSS--SIVAYQPAGD 278
           L+F +       + V  I   + ++VE YAL+FG   +N  +A+V+ +  +++     G 
Sbjct: 377 LIFKSSYMLLITIAVFQI--AVNLNVERYALVFG---INTFIALVIQTIMTVIVVDQRGL 431

Query: 279 NSHTFDVTAMFKSIGIFLGIFSGSFAM 305
           N     V+  F   G +  + +G F M
Sbjct: 432 N---LPVSIQFLVYGSYFAVIAGIFLM 455


>gi|215820660 ATP-binding cassette, subfamily G, member 4 [Homo
           sapiens]
          Length = 646

 Score = 31.2 bits (69), Expect = 3.2
 Identities = 20/75 (26%), Positives = 34/75 (45%), Gaps = 16/75 (21%)

Query: 290 KSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLLETGLFF-------LMSWSTFL 342
           +S+G+ +G  S S  +    G VTA+           LL +G F         + WS++L
Sbjct: 518 QSLGLLIGAASNSLQVATFVGPVTAIPV---------LLFSGFFVSFKTIPTYLQWSSYL 568

Query: 343 LAEAWGFTGVVAVLF 357
               +GF GV+  ++
Sbjct: 569 SYVRYGFEGVILTIY 583


>gi|20143975 ATP-binding cassette, subfamily G, member 4 [Homo
           sapiens]
          Length = 646

 Score = 31.2 bits (69), Expect = 3.2
 Identities = 20/75 (26%), Positives = 34/75 (45%), Gaps = 16/75 (21%)

Query: 290 KSIGIFLGIFSGSFAMGAATGVVTALVTKFTKLREFQLLETGLFF-------LMSWSTFL 342
           +S+G+ +G  S S  +    G VTA+           LL +G F         + WS++L
Sbjct: 518 QSLGLLIGAASNSLQVATFVGPVTAIPV---------LLFSGFFVSFKTIPTYLQWSSYL 568

Query: 343 LAEAWGFTGVVAVLF 357
               +GF GV+  ++
Sbjct: 569 SYVRYGFEGVILTIY 583


>gi|164698502 septin 9 isoform d [Homo sapiens]
          Length = 474

 Score = 30.8 bits (68), Expect = 4.2
 Identities = 13/24 (54%), Positives = 17/24 (70%)

Query: 1  MARRGWRRAPLRRGVGSSPRARRL 24
          + R GWR+  LRRG G+S R R+L
Sbjct: 55 LGRGGWRQGSLRRGKGTSCRCRQL 78


>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
          Length = 2028

 Score = 30.4 bits (67), Expect = 5.5
 Identities = 27/116 (23%), Positives = 48/116 (41%), Gaps = 5/116 (4%)

Query: 558  TTTLPACCGPIARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTEPATSSAP 617
            TTT P+   PIAR     + Y + + L +   +  + +    ++   S  ++   +S++ 
Sbjct: 1525 TTTAPSNSTPIARHPGRTKGYNSDDNLCEPSLEFEVPNHRQYVSRPSSLESSRNTSSNSS 1584

Query: 618  RRFMGNSSEDALDRELAFGDHELVIRGTRLVLPMDDSEPPLNLLDN-----TRHGP 668
               +  SSE    R  +F   +L+       LP + S P  N L        R+GP
Sbjct: 1585 PLNLKGSSEQLHGRSESFSSEDLIPSRDLATLPREASTPGRNALGRHEYPLPRNGP 1640


>gi|4557373 biotinidase precursor [Homo sapiens]
          Length = 543

 Score = 30.0 bits (66), Expect = 7.2
 Identities = 24/81 (29%), Positives = 34/81 (41%), Gaps = 11/81 (13%)

Query: 482 TLLIVFFTVWVFGG-----GTTAMLSCLHIRVGVDSDQEHLGVPENERRTTKAESAWLFR 536
           TL    + + VF G     GT  +  C  +R G       LG     +  T+A   + F 
Sbjct: 432 TLSKELYALGVFDGLHTVHGTYYIQVCALVRCG------GLGFDTCGQEITEATGIFEFH 485

Query: 537 MWYNFDHNYLKPLLTHSGPPL 557
           +W NF  +Y+ PL   SG  L
Sbjct: 486 LWGNFSTSYIFPLFLTSGMTL 506


>gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]
          Length = 1303

 Score = 30.0 bits (66), Expect = 7.2
 Identities = 22/67 (32%), Positives = 28/67 (41%), Gaps = 5/67 (7%)

Query: 553 SGPPLTTTLPACCGPIARCLTSPQAYENQEQLKDDDSDLILNDGDISLTYGDSTVNTEPA 612
           S PP +T  P  C P AR  T P    ++  L DD  D  L +G++     D        
Sbjct: 20  SPPPPSTPSPPPCSPDARPAT-PHLLHHRLPLPDDREDGELEEGELE----DDGAEETQD 74

Query: 613 TSSAPRR 619
           TS  P R
Sbjct: 75  TSGGPER 81


>gi|46852164 mannosidase, alpha, class 2C, member 1 [Homo sapiens]
          Length = 1040

 Score = 29.6 bits (65), Expect = 9.4
 Identities = 14/37 (37%), Positives = 20/37 (54%)

Query: 203 TLMKVTGQLAGDFYFTDCLLFGAIVSATDPVTVLAIF 239
           T ++   +     YFTDC L G +  A+ PV VL+ F
Sbjct: 12  TTLERVEKFVSPLYFTDCNLRGRLFGASCPVAVLSSF 48


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.139    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,691,876
Number of Sequences: 37866
Number of extensions: 1006727
Number of successful extensions: 3174
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 3114
Number of HSP's gapped (non-prelim): 31
length of query: 669
length of database: 18,247,518
effective HSP length: 109
effective length of query: 560
effective length of database: 14,120,124
effective search space: 7907269440
effective search space used: 7907269440
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.