Search of human proteins with 5453904

Search of human proteins with 5453904

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5453904 RAD51 associated protein 1 isoform b [Homo sapiens]
         (335 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5453904 RAD51 associated protein 1 isoform b [Homo sapiens]        655   0.0  
gi|195947391 RAD51 associated protein 1 isoform a [Homo sapiens]      644   0.0  
gi|56118310 nuclear casein kinase and cyclin-dependent kinase su...    84   1e-16
gi|104526627 triadin [Homo sapiens]                                    51   1e-06
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     50   2e-06
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo...    50   4e-06
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo...    50   4e-06
gi|5453567 craniofacial development protein 1 [Homo sapiens]           50   4e-06
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]       45   7e-05
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]           44   2e-04
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]           44   2e-04
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor...    44   2e-04
gi|156104891 general transcription factor IIF, polypeptide 1, 74...    43   3e-04
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo...    43   3e-04
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [...    43   5e-04
gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]             43   5e-04
gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]             43   5e-04
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    42   6e-04
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    42   6e-04
gi|4507241 structure specific recognition protein 1 [Homo sapiens]     42   6e-04
gi|55769587 probable nucleolar complex protein 14 [Homo sapiens]       42   8e-04
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    42   8e-04
gi|217330641 IWS1 homolog [Homo sapiens]                               42   8e-04
gi|34482047 adaptor-related protein complex 3, beta 2 subunit [H...    40   0.002
gi|48255931 hepatoma-derived growth factor-related protein 2 iso...    40   0.002
gi|14249158 hepatoma-derived growth factor-related protein 2 iso...    40   0.002
gi|27734775 hypothetical protein LOC286499 [Homo sapiens]              40   0.002
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    40   0.003
gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens]    40   0.003
gi|192807332 arsenate resistance protein 2 isoform c [Homo sapiens]    40   0.003

>gi|5453904 RAD51 associated protein 1 isoform b [Homo sapiens]
          Length = 335

 Score =  655 bits (1690), Expect = 0.0
 Identities = 335/335 (100%), Positives = 335/335 (100%)

Query: 1   MVRPVRHKKPVNYSQFDHSDSDDDFVSATVPLNKKSRTAPKELKQDKPKPNLNNLRKEEI 60
           MVRPVRHKKPVNYSQFDHSDSDDDFVSATVPLNKKSRTAPKELKQDKPKPNLNNLRKEEI
Sbjct: 1   MVRPVRHKKPVNYSQFDHSDSDDDFVSATVPLNKKSRTAPKELKQDKPKPNLNNLRKEEI 60

Query: 61  PVQEKTPKKRMALDDKLYQRDLEVALALSVKELPTVTTNVQNSQDKSIEKHGSSKIETMN 120
           PVQEKTPKKRMALDDKLYQRDLEVALALSVKELPTVTTNVQNSQDKSIEKHGSSKIETMN
Sbjct: 61  PVQEKTPKKRMALDDKLYQRDLEVALALSVKELPTVTTNVQNSQDKSIEKHGSSKIETMN 120

Query: 121 KSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTE 180
           KSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTE
Sbjct: 121 KSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTE 180

Query: 181 PDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNAL 240
           PDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNAL
Sbjct: 181 PDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNAL 240

Query: 241 VTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESKKPKWVPPAASGGSRSSS 300
           VTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESKKPKWVPPAASGGSRSSS
Sbjct: 241 VTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESKKPKWVPPAASGGSRSSS 300

Query: 301 SPLVVVSVKSPNQSLRLGLSRLARVKPLHPNATST 335
           SPLVVVSVKSPNQSLRLGLSRLARVKPLHPNATST
Sbjct: 301 SPLVVVSVKSPNQSLRLGLSRLARVKPLHPNATST 335


>gi|195947391 RAD51 associated protein 1 isoform a [Homo sapiens]
          Length = 352

 Score =  644 bits (1662), Expect = 0.0
 Identities = 335/352 (95%), Positives = 335/352 (95%), Gaps = 17/352 (4%)

Query: 1   MVRPVRHKKPVNYSQFDHSDSDDDFVSATVPLNKKSRTAPKELKQDKPKPNLNNLRKEEI 60
           MVRPVRHKKPVNYSQFDHSDSDDDFVSATVPLNKKSRTAPKELKQDKPKPNLNNLRKEEI
Sbjct: 1   MVRPVRHKKPVNYSQFDHSDSDDDFVSATVPLNKKSRTAPKELKQDKPKPNLNNLRKEEI 60

Query: 61  PVQEKTPKKR-----------------MALDDKLYQRDLEVALALSVKELPTVTTNVQNS 103
           PVQEKTPKKR                 MALDDKLYQRDLEVALALSVKELPTVTTNVQNS
Sbjct: 61  PVQEKTPKKRLPEGTFSIPASAVPCTKMALDDKLYQRDLEVALALSVKELPTVTTNVQNS 120

Query: 104 QDKSIEKHGSSKIETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQ 163
           QDKSIEKHGSSKIETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQ
Sbjct: 121 QDKSIEKHGSSKIETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQ 180

Query: 164 RKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVK 223
           RKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVK
Sbjct: 181 RKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVK 240

Query: 224 SPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESK 283
           SPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESK
Sbjct: 241 SPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESK 300

Query: 284 KPKWVPPAASGGSRSSSSPLVVVSVKSPNQSLRLGLSRLARVKPLHPNATST 335
           KPKWVPPAASGGSRSSSSPLVVVSVKSPNQSLRLGLSRLARVKPLHPNATST
Sbjct: 301 KPKWVPPAASGGSRSSSSPLVVVSVKSPNQSLRLGLSRLARVKPLHPNATST 352


>gi|56118310 nuclear casein kinase and cyclin-dependent kinase
           substrate 1 [Homo sapiens]
          Length = 243

 Score = 84.3 bits (207), Expect = 1e-16
 Identities = 85/305 (27%), Positives = 125/305 (40%), Gaps = 77/305 (25%)

Query: 1   MVRPVRHKKPVNYSQFDHS-DSDDDFVSATVPLNKKSRTAPKELKQDKPKPNLNNLRKEE 59
           M RPVR++K V+YSQF  S D+D+D+   + P  KK R++P+E K               
Sbjct: 1   MSRPVRNRKVVDYSQFQESDDADEDYGRDSGPPTKKIRSSPREAKN-------------- 46

Query: 60  IPVQEKTPKKRMALDDKLYQRDLEVALALSVKELPTVTTNVQNSQDKSIEKHGSSKIETM 119
                   K+R                              +NSQ+ S E      ++T 
Sbjct: 47  --------KRRSG----------------------------KNSQEDS-EDSEDKDVKTK 69

Query: 120 NKSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQRKILLE--GSDGDSAN 177
               H +           D    ++D   V+ +R+AASKAA++QR++L+E  GS+ +   
Sbjct: 70  KDDSHSAE----------DSEDEKEDHKNVRQQRQAASKAASKQREMLMEDVGSEEEQEE 119

Query: 178 DTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKC 237
           + E  F   +DS  D DF   +D+D D+   K K     KK VK   P  K++K  K + 
Sbjct: 120 EDEAPFQE-KDSGSDEDFLMEDDDDSDYGSSKKK----NKKMVKKSKPERKEKKMPKPRL 174

Query: 238 NALVTSVDSAPAAVKSESQ-SLPKKVSLSSDTTRKPLE--IRSPSAESKKPKWVPPAASG 294
            A VT     P+ VK + +   P     S + T  P E      S   KK    PP    
Sbjct: 175 KATVT-----PSPVKGKGKVGRPTASKASKEKTPSPKEEDEEPESPPEKKTSTSPPPEKS 229

Query: 295 GSRSS 299
           G   S
Sbjct: 230 GDEGS 234


>gi|104526627 triadin [Homo sapiens]
          Length = 729

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 72/338 (21%), Positives = 116/338 (34%), Gaps = 44/338 (13%)

Query: 4   PVRHKKPVNYSQFDHSDSDDDFVSATVPLNKKSRTAPKELKQDKPKPNLNNLRKEEIPVQ 63
           P   KK ++  + +  +  +  +   V   +K +   KE  ++K KP      KE+I  +
Sbjct: 136 PPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKG--KEKVREKEKPEKKATHKEKIEKK 193

Query: 64  EKTPKKRMALDDK----------LYQRDLEVALALSVKELPTVTTNVQNSQDKSIEKHGS 113
           EK   K +A + K            +++++      VK+       VQ +  K  EK   
Sbjct: 194 EKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEKEDK 253

Query: 114 SK--IETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQRKILLEGS 171
            K  +    +    + C    D               V G  K     A      +    
Sbjct: 254 EKAAVSKHEQKDQYAFCRYMIDIF-------------VHGDLKPGQSPA------IPPPL 294

Query: 172 DGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEK 231
             + A+   P     E+ E +    E +   E     K  +K  KK E +    VEKKE 
Sbjct: 295 PTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIK--KKSEKETAIDVEKKEP 352

Query: 232 KSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSA--ESKKPKWVP 289
              S+       + +  AA K E +   KK       T+KP E+  P    + KK K V 
Sbjct: 353 GKASETKQGTVKIAAQAAAKKDEKKEDSKK-------TKKPAEVEQPKGKKQEKKEKHVE 405

Query: 290 PAASGGSRSSSSPLVVVSVKSPNQSLRLGLSRLARVKP 327
           PA S     S      V  K+      +G   + +  P
Sbjct: 406 PAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVP 443



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 30/107 (28%), Positives = 44/107 (41%), Gaps = 11/107 (10%)

Query: 182 DFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALV 241
           D    ED EDD       D DED    +     ++KKE+  K   EK+EK  + K    V
Sbjct: 112 DIISSEDEEDD-------DGDEDTDKGEIDEPPLRKKEIH-KDKTEKQEKPER-KIQTKV 162

Query: 242 TSVDSAPAAVKSESQSLPKKVSLSSDTTRK--PLEIRSPSAESKKPK 286
           T  +      K   +  P+K +   +   K    E ++ + E KK K
Sbjct: 163 THKEKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAK 209


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 54/232 (23%), Positives = 102/232 (43%), Gaps = 36/232 (15%)

Query: 85  ALALSVKELPTVTTNVQNSQDKSIEKHGSSKIETMNKSPHISNCSVASDYLDLDKITVED 144
           +L   + ++P+V+T+++   ++ I+    S+ ET+          V       +++T E+
Sbjct: 421 SLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVT------EEVTEEE 474

Query: 145 DVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDED 204
           +            K A ++     EG + +   + E      E  E+++    +E+    
Sbjct: 475 E------------KEAKEE-----EGKEEEGGEEEE-----AEGGEEETKSPPAEEAASP 512

Query: 205 FSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSL 264
               KS VKE  K   + KSP EK+E KS ++    V S + A +  K E++S P+  S 
Sbjct: 513 EKEAKSPVKEEAKSPAEAKSP-EKEEAKSPAE----VKSPEKAKSPAKEEAKSPPEAKSP 567

Query: 265 SSDTTRKPLEIRSP--SAESKKPKWVPPAASGGSRSSSSPLVVVSVKSPNQS 314
             +  + P E++SP  +    K +   PA +     + SP V    KSP ++
Sbjct: 568 EKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSP-VKEEAKSPAEA 618



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 36/109 (33%), Positives = 55/109 (50%), Gaps = 7/109 (6%)

Query: 209 KSKVKEIKKKEVKVKSPVEKKEK---KSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLS 265
           KS VKE  K   K KSPV+++ K   K+KS       + + A + VK E++S P+K    
Sbjct: 695 KSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKS-PEKA--K 751

Query: 266 SDTTRKPLEIRSPSAESKKPKWVPPAASGGSRSSSSPLVVVSVKSPNQS 314
           S    K L+++SP A++   +     A      + SP V   VKSP ++
Sbjct: 752 SPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSP-VKEEVKSPEKA 799



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 61/275 (22%), Positives = 113/275 (41%), Gaps = 24/275 (8%)

Query: 57  KEEIPVQEKTPKKRMALDDKLYQRDLEVALALSVKELPTVTTNVQNSQDKSIEKHGSSKI 116
           +E+I V EK+ K+ + ++++  +  +   +    +E        +  +++  E+  +   
Sbjct: 441 EEKIKVVEKSEKETVIVEEQTEETQVTEEVT---EEEEKEAKEEEGKEEEGGEEEEAEGG 497

Query: 117 ETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQGK--RKAASKAAAQQRKILLEGSDGD 174
           E   KSP       AS   +      E+     + K   K  +K+ A+ +      S   
Sbjct: 498 EEETKSPPAEEA--ASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAK 555

Query: 175 SANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVK---EIKKKEVKVKSPVEKKEK 231
               + P+ A   + E+     E +  ++  S  K + K   E K  E K KSPV+++ K
Sbjct: 556 EEAKSPPE-AKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPE-KAKSPVKEEAK 613

Query: 232 ---------KSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSP-SAE 281
                    K ++K  A V S + A +  K E++S  K  S   +  + P + +SP  AE
Sbjct: 614 SPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAE 673

Query: 282 SKKPKWV--PPAASGGSRSSSSPLVVVSVKSPNQS 314
           +K P+    P  A   S   +   V    KSP ++
Sbjct: 674 AKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKA 708



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 36/134 (26%), Positives = 56/134 (41%), Gaps = 5/134 (3%)

Query: 156 ASKAAAQQRKILLEGSDGDSANDTEPDFA--PGEDSEDDSDFCESEDNDEDFSMRKSKVK 213
           A   A ++ K   E    + A     + A  P E      +  +S    +     KS  K
Sbjct: 584 AKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTK 643

Query: 214 EIKKKEVKVKSPVEKKEK---KSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTR 270
           E  K   K KSP +++ K   K+KS   A   S + A + VK+E++S  K  S   +  +
Sbjct: 644 EEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAK 703

Query: 271 KPLEIRSPSAESKK 284
            P + +SP  E  K
Sbjct: 704 SPEKAKSPVKEEAK 717



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 61/271 (22%), Positives = 106/271 (39%), Gaps = 28/271 (10%)

Query: 28  ATVPLNKKSRTAPKELKQDKPKPNLNNLRKEEIPVQEKTPKKRMALDDKLYQRDLEVALA 87
           A V   +K+++  KE  +   K       + + P + K+P K  A   +  +  ++    
Sbjct: 630 AEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEA- 688

Query: 88  LSVKELPTVTTNVQNSQDKSIEKHGSSKIETMNKSPHISNCSVASDYLDLDKITVEDDVG 147
               + P    +    + KS EK   S ++   KSP  +   V  +       T E    
Sbjct: 689 ----KSPEKAKSPVKEEAKSPEK-AKSPVKEEAKSPEKAKSPVKEEAK-----TPEKAKS 738

Query: 148 GVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSM 207
            V+ + K+  KA + ++   L+    ++    + +     D   +    +S   +E  S 
Sbjct: 739 PVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEK--AKSPVKEEVKSP 796

Query: 208 RKSKV----------KEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDS--APAAVKSES 255
            K+K           KEI KKE +VKSPV+++EK  + K        +   APA  K+E 
Sbjct: 797 EKAKSPLKEDAKAPEKEIPKKE-EVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEE 855

Query: 256 QSLPKKVSLSSDTTRKPL--EIRSPSAESKK 284
           +   KK         KP   E + P+ E  K
Sbjct: 856 KKDSKKEEAPKKEAPKPKVEEKKEPAVEKPK 886



 Score = 36.2 bits (82), Expect = 0.042
 Identities = 44/230 (19%), Positives = 91/230 (39%), Gaps = 31/230 (13%)

Query: 34  KKSRTAPKELKQDKPKPNLNNLRKEEI--PVQEKTPKKRMALDDKLYQRDLEVALALSVK 91
           K    A   LK+D   P     +KEE+  PV+E+   + + + +   + + E A A    
Sbjct: 794 KSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPAT--- 850

Query: 92  ELPTVTTNVQNSQDKSIEKHGSSKIETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQG 151
             P       + ++++ +K          K P +                        + 
Sbjct: 851 --PKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPK--------------------ES 888

Query: 152 KRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSE---DDSDFCESEDNDEDFSMR 208
           K +A  + A  ++K+     +  +  + + D  P E +E    + D  ++++  +    +
Sbjct: 889 KVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKK 948

Query: 209 KSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVD-SAPAAVKSESQS 257
           ++  ++   KE K K P EK + ++K+K +    S + S P A K+E  S
Sbjct: 949 EAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSS 998



 Score = 34.7 bits (78), Expect = 0.12
 Identities = 56/275 (20%), Positives = 105/275 (38%), Gaps = 21/275 (7%)

Query: 34  KKSRTAPKELKQDKPKPNLNNLRKEEIPVQEKTPKKRMALDDKLYQRDLEVALALSVKEL 93
           +K+++  KE  +   K       + + P + K+P K  A   +   +  E A  L VK  
Sbjct: 706 EKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEK-AKSPEKAKTLDVKSP 764

Query: 94  PTVTTNVQNSQ---DKSIEKHGSSKIETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQ 150
              T   + ++   DK  EK   S ++   KSP  +   +  D    +K          +
Sbjct: 765 EAKTPAKEEARSPADKFPEK-AKSPVKEEVKSPEKAKSPLKEDAKAPEK----------E 813

Query: 151 GKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKS 210
             +K   K+  ++ +   E    +     E + AP     ++    + E+  +     K 
Sbjct: 814 IPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKK-EAPKP 872

Query: 211 KVKEIKKKEVKVKSPVEKKEKKSKSKCN---ALVTSVDSAPAAVKSESQSLPKKVSLSSD 267
           KV+E  KKE  V+ P E K +  K +      + T    APA V+ +  + PK+ +  + 
Sbjct: 873 KVEE--KKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAK 930

Query: 268 TTRKPLEIRSPSAESKKPKWVPPAASGGSRSSSSP 302
                 + + PS  ++K +  P         +  P
Sbjct: 931 KEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKP 965


>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform b
            [Homo sapiens]
          Length = 1524

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 48/169 (28%), Positives = 77/169 (45%), Gaps = 12/169 (7%)

Query: 153  RKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESE-DNDEDFSMRKSK 211
            ++ + + +++QR  L    D + +   E D   G++ E  S+  E E + DED S  + +
Sbjct: 1166 KQRSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEE 1225

Query: 212  VKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRK 271
            V   K+   +V+ PV+ + K S S  +         P    S SQ    K ++SS T R 
Sbjct: 1226 VSLPKRGRPQVRLPVKTRGKLSSSFSS---RGQQQEPGRYPSRSQQSTPKTTVSSKTGRS 1282

Query: 272  PLEIRS-PSAESKKPKWVPPAASGGSRSSSSPL---VVVSVKSPNQSLR 316
              +I S P  E+K  +     AS  +R S  PL   V V + SP +  R
Sbjct: 1283 LRKINSAPPTETKSLR----IASRSTRHSHGPLQADVFVELLSPRRKRR 1327



 Score = 29.6 bits (65), Expect = 4.0
 Identities = 26/102 (25%), Positives = 49/102 (48%), Gaps = 13/102 (12%)

Query: 140 ITVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESE 199
           I+ ED+V   Q      SKA  ++ K+L +      A      F   +   + +D  E++
Sbjct: 285 ISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLA------FEKAKLKREKADALEAK 338

Query: 200 DND-EDFSMRKSKVKEI------KKKEVKVKSPVEKKEKKSK 234
             + ED   ++ ++K+I      KKKE K +  VE+++++ K
Sbjct: 339 KKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREK 380


>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform a
            [Homo sapiens]
          Length = 1556

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 48/169 (28%), Positives = 77/169 (45%), Gaps = 12/169 (7%)

Query: 153  RKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESE-DNDEDFSMRKSK 211
            ++ + + +++QR  L    D + +   E D   G++ E  S+  E E + DED S  + +
Sbjct: 1198 KQRSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEE 1257

Query: 212  VKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRK 271
            V   K+   +V+ PV+ + K S S  +         P    S SQ    K ++SS T R 
Sbjct: 1258 VSLPKRGRPQVRLPVKTRGKLSSSFSS---RGQQQEPGRYPSRSQQSTPKTTVSSKTGRS 1314

Query: 272  PLEIRS-PSAESKKPKWVPPAASGGSRSSSSPL---VVVSVKSPNQSLR 316
              +I S P  E+K  +     AS  +R S  PL   V V + SP +  R
Sbjct: 1315 LRKINSAPPTETKSLR----IASRSTRHSHGPLQADVFVELLSPRRKRR 1359



 Score = 29.6 bits (65), Expect = 4.0
 Identities = 26/102 (25%), Positives = 49/102 (48%), Gaps = 13/102 (12%)

Query: 140 ITVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESE 199
           I+ ED+V   Q      SKA  ++ K+L +      A      F   +   + +D  E++
Sbjct: 285 ISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLA------FEKAKLKREKADALEAK 338

Query: 200 DND-EDFSMRKSKVKEI------KKKEVKVKSPVEKKEKKSK 234
             + ED   ++ ++K+I      KKKE K +  VE+++++ K
Sbjct: 339 KKEKEDKEKKREELKKIVEEERLKKKEEKERLKVEREKEREK 380


>gi|5453567 craniofacial development protein 1 [Homo sapiens]
          Length = 299

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 48/214 (22%), Positives = 88/214 (41%), Gaps = 38/214 (17%)

Query: 136 DLDKITVEDDVGG------VQGKRKAASKAAAQQRK---ILLEGSDGDSANDTEPDFAPG 186
           D++++  ED+V G       QGK++ A    A++R+   + LE  + + AN      + G
Sbjct: 29  DVNELVKEDEVDGEEQTQKTQGKKRKAQSIPARKRRQGGLSLEEEEEEDANSE----SEG 84

Query: 187 EDSEDDSDFCESEDNDEDFSMRKSKVKEI---------KKKEVKVKSPVEKKEKKSKSKC 237
             SE++ D  E E        RK K  E+          K +V   + V+K E+  ++  
Sbjct: 85  SSSEEEDDAAEQEKGIGSEDARKKKEDELWASFLNDVGPKSKVPPSTQVKKGEETEETSS 144

Query: 238 NALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESKK------------- 284
           + L+   +      ++E   + K    + +  R   E+ + S E+K              
Sbjct: 145 SKLLVKAEELEKPKETEKVKITKVFDFAGEEVRVTKEVDATSKEAKSFFKQNEKEKPQAN 204

Query: 285 -PKWVP--PAASGGSRSSSSPLVVVSVKSPNQSL 315
            P  +P  PA SG  RSS    ++  + +  Q +
Sbjct: 205 VPSALPSLPAGSGLKRSSGMSSLLGKIGAKKQKM 238


>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
          Length = 1007

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 78/333 (23%), Positives = 130/333 (39%), Gaps = 47/333 (14%)

Query: 33  NKKSRTAPKELKQDKPKPNLNNLRKEEIPVQEK---TPKKRMALDDKLYQRDLEVALALS 89
           +K S    K+ K      +  + RKE I   +K   +P KR  LDD     DLE   AL 
Sbjct: 57  HKHSSEEDKDKKHKHKHKHKKHKRKEIIDASDKEGMSPAKRTKLDDLALLEDLEKQRALI 116

Query: 90  VKELPT--VTTNVQNSQDKSIE--KHGSSKIETMNKSPHISNCSVASDYLDLDKITVEDD 145
             EL    +   VQ+     ++  + GS +   +++     N S         K+ + D+
Sbjct: 117 KAELDNELMEGKVQSGMGLILQGYESGSEEEGEIHEKARNGNRSSTRSSSTKGKLELVDN 176

Query: 146 VGGVQGKRKAASKAAAQQR----------KILLEGSDGDSANDTEPDFAPGEDSEDDSDF 195
               + + K+ SK   + R          +I+ E +    + + +   +P + S+     
Sbjct: 177 KITTKKRSKSRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQA 236

Query: 196 CESED------NDEDFSMRKSKVKEIKKKEVKVKSPVEKK-----EKKSKSKCNALVTSV 244
            +S+       + E     +S   +  K E K KS   KK     E +S+ +     + V
Sbjct: 237 RKSKSPTLRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPV 296

Query: 245 DSAPAAVKSESQSLPKKVSLS-SDTTRKPL-----------EIRSPS---AESKKPKWVP 289
           D    +    S+S  +K   S +D  +KP+           E RSPS     S K + + 
Sbjct: 297 DLRGKSKDRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPGRSPKRRSLS 356

Query: 290 PAASGGSRSSSSPLV----VVSVKSPNQSLRLG 318
           P     SR S SPL+        KSP+++L  G
Sbjct: 357 PKPRDKSRRSRSPLLNDRRSKQSKSPSRTLSPG 389


>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
          Length = 330

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 48/176 (27%), Positives = 81/176 (46%), Gaps = 25/176 (14%)

Query: 133 DYLDLDKITVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDD 192
           +Y++ ++   E D  G + K+K   KA      IL E  D +S  + E      ++ ED 
Sbjct: 113 EYIEREESDGEYDEFG-RKKKKYRGKAVGPA-SILKEVEDKESEGEEE------DEDEDL 164

Query: 193 SDFCESEDNDED------FSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDS 246
           S +   ED DED      +++  S+ ++  KK+   +S  + +   S+S      +S  S
Sbjct: 165 SKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRS------SSRSS 218

Query: 247 APAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESKKPKWVPPAASGGSRSSSSP 302
           +P++ +S S+S  +  S S   +R     RS S  SK       ++S   R SSSP
Sbjct: 219 SPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKS-----RSSSRSHRGSSSP 269


>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
          Length = 320

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 48/176 (27%), Positives = 81/176 (46%), Gaps = 25/176 (14%)

Query: 133 DYLDLDKITVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDD 192
           +Y++ ++   E D  G + K+K   KA      IL E  D +S  + E      ++ ED 
Sbjct: 113 EYIEREESDGEYDEFG-RKKKKYRGKAVGPA-SILKEVEDKESEGEEE------DEDEDL 164

Query: 193 SDFCESEDNDED------FSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDS 246
           S +   ED DED      +++  S+ ++  KK+   +S  + +   S+S      +S  S
Sbjct: 165 SKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRS------SSRSS 218

Query: 247 APAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESKKPKWVPPAASGGSRSSSSP 302
           +P++ +S S+S  +  S S   +R     RS S  SK       ++S   R SSSP
Sbjct: 219 SPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKS-----RSSSRSHRGSSSP 269


>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 3 [Homo sapiens]
          Length = 568

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 63/277 (22%), Positives = 108/277 (38%), Gaps = 66/277 (23%)

Query: 40  PKEL-KQDKPKPNLNNLRKEEIPVQEKTPKKRMALDD------KLYQRDLEVALALSVKE 92
           PK + K+ KP  NL  +   +    +K P KR  + D      K  ++    AL  S   
Sbjct: 256 PKPMSKEPKPDSNLLTITSGQ---DKKAPSKRPPISDSEELSAKKRKKSSSEALFKSFSS 312

Query: 93  LP----TVTTNVQNSQDKSIEKHGSSKIETMNKSPHISNCSVASDYLDLDKITVEDDVGG 148
            P    T + + +  +DKS  K G  KIE+       S      D +D +   VE+++  
Sbjct: 313 APPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVDPNDSDVEENI-- 370

Query: 149 VQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGE-----------------DSED 191
                  +SK+ ++Q       S   S++ +   F P +                 D+E+
Sbjct: 371 -------SSKSDSEQP------SPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEE 417

Query: 192 DSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAAV 251
           +SD  E  DND +                 ++ PV +    S+S+  +L    DS  ++ 
Sbjct: 418 ESDEVEDNDNDSE-----------------MERPVNR--GGSRSRRVSLSDGSDSESSSA 458

Query: 252 KSESQSLPKKVSLSSDTTRKPLEIRSPSAESKKPKWV 288
            S     P    L ++   + LE++SP  +SK  K +
Sbjct: 459 SSPLHHEPPPPLLKTN-NNQILEVKSPIKQSKSDKQI 494


>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
           [Homo sapiens]
          Length = 517

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 52/241 (21%), Positives = 97/241 (40%), Gaps = 22/241 (9%)

Query: 78  YQRDLEVALALSVKELPTVTTNVQNSQDKSIEKHGSSKIETMNKSPHISNCSVASDYLDL 137
           ++R  +V    S+ +   +    Q+  ++  EK G  K   +       +  ++SD  D 
Sbjct: 164 WERRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRGRRKASELRIHDLEDDLEMSSDASDA 223

Query: 138 DKITVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCE 197
                 ++ G V   +K A  A   ++K   +GSD ++  D++     G++ +  SD   
Sbjct: 224 SG----EEGGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSS 279

Query: 198 SEDNDEDFSMRKSKVKEIKK----------KEVKVKSPVEKKEKKSKSKC---NALVTSV 244
           S   + +   +  + +E  K          +  + K P E KE++ + K           
Sbjct: 280 SSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEEKKAPTPQEKKRRK 339

Query: 245 DSAPAAVKSESQSLPKKVSLSSDTTRK---PLEIRSPSAESKKPKWVP--PAASGGSRSS 299
           DS+  +  SE   +  + S +    +K   P   R PS  S +    P  P+A GGS SS
Sbjct: 340 DSSEESDSSEESDIDSEASSALFMAKKKTPPKRERKPSGGSSRGNSRPGTPSAEGGSTSS 399

Query: 300 S 300
           +
Sbjct: 400 T 400


>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
           sapiens]
          Length = 2168

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 8/98 (8%)

Query: 171 SDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKE 230
           SD +S +DTE     G + EDD D  + +++D D    K+ +K + K    VKSP     
Sbjct: 635 SDSNSESDTE-----GSEEEDDDDK-DQDESDSDTEGEKTSMK-LNKTTSSVKSPSMSLT 687

Query: 231 KKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDT 268
             S  +   +  +  SAPAA+ SESQS P  +  SS T
Sbjct: 688 GHSTPRNLHIAKAPGSAPAALCSESQS-PAFLGTSSST 724



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 27/129 (20%), Positives = 58/129 (44%), Gaps = 20/129 (15%)

Query: 163 QRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKV 222
           ++K +   S+ DS + T  D +    S  DSD  E ++ +ED S+ +S+  +        
Sbjct: 235 RKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSD------ 288

Query: 223 KSPVEKKEKKSKSKCNALVTSV-----DSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRS 277
                + E + KS    L+  +     D   A  K++ + + + + L+S++     +  S
Sbjct: 289 ----SESEAQHKSNNQVLLHGISDPKADGQKATEKAQEKRIHQPLPLASES-----QTHS 339

Query: 278 PSAESKKPK 286
             ++ K+P+
Sbjct: 340 FQSQQKQPQ 348



 Score = 30.8 bits (68), Expect = 1.8
 Identities = 47/191 (24%), Positives = 73/191 (38%), Gaps = 28/191 (14%)

Query: 150 QGKRKAASKAA--------AQQRKILLEGSDGDSANDTEPDFAPGEDSED------DSDF 195
           QGK KA S           +   K L+E   G     T+ D    +DSED      + D 
Sbjct: 562 QGKEKAVSNNVNPVKTQHHSHPAKSLVEQFRG-----TDSDIPSSKDSEDSNEDEEEDDE 616

Query: 196 CESEDNDEDFSMRKSKVKEIKKKEVKVK-SPVEKKEKKSKSKCNALVTSVDSAPAAVKSE 254
            E E++DED     S+ +     E   + S  E  + K + + ++      ++    K+ 
Sbjct: 617 EEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTT 676

Query: 255 SQSLPKKVSLSSDTTRKPLEIRSPSAESKKPKWVPPAASGGSRSSSSPLVVVSVKSPNQS 314
           S      +SL+  +T + L I      +K P   P A    S S S   +  S  +   S
Sbjct: 677 SSVKSPSMSLTGHSTPRNLHI------AKAPGSAPAALC--SESQSPAFLGTSSSTLTSS 728

Query: 315 LRLGLSRLARV 325
              G S+  RV
Sbjct: 729 PHSGTSKRRRV 739



 Score = 28.5 bits (62), Expect = 8.8
 Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 10/57 (17%)

Query: 171  SDGDSANDTEPDFAPGEDSEDD----------SDFCESEDNDEDFSMRKSKVKEIKK 217
            SD D  +D + D    ED ED+          +D CE ED  +  +  +   K+I+K
Sbjct: 1297 SDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAASVEELEKQIEK 1353


>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
            sapiens]
          Length = 3969

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 13/110 (11%)

Query: 209  KSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDT 268
            + + K +KKKE K K+  +K  K+S    N + +S    P+A +  +   PKK S S   
Sbjct: 1207 QKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPA---PKKSS-SEPP 1262

Query: 269  TRKPLEIRS-------PSAESKKPKWVPPAASGGSRSSSSPLVVVSVKSP 311
             RKP+E +S       P  ESK+     PA+   S+  S P +V+  + P
Sbjct: 1263 PRKPVEEKSEEGNVSAPGPESKQA--TTPASRKSSKQVSQPALVIPPQPP 1310



 Score = 32.7 bits (73), Expect = 0.47
 Identities = 32/137 (23%), Positives = 56/137 (40%), Gaps = 7/137 (5%)

Query: 151 GKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSE-----DDSDFCESEDNDEDF 205
           G+    ++   +Q     E     S     P F PG  +E     D +    S+D D D 
Sbjct: 807 GESAEKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADK 866

Query: 206 SMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLS 265
           S+ K K +E  ++  K      +KEK+ K   + + +S    P    S+ + + + V+ S
Sbjct: 867 SVEKDKSRERDREREKENKRESRKEKRKKG--SEIQSSSALYPVGRVSKEKVVGEDVATS 924

Query: 266 SDTTRKPLEIRSPSAES 282
           S   +     +S S +S
Sbjct: 925 SSAKKATGRKKSSSHDS 941



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 64/279 (22%), Positives = 105/279 (37%), Gaps = 19/279 (6%)

Query: 28   ATVPLNKKSRTAPKELKQDKPKPNLNNLRKEEIPVQEKTPKKRMALDDKLYQRDLEVA-- 85
            A V L +K    P ++      P L+ L  EE   +EK     M  DDK      E A  
Sbjct: 1075 AAVALGRKRAVFPDDM------PTLSALPWEE---REKILSS-MGNDDKSSIAGSEDAEP 1124

Query: 86   LALSVKELPTVTTNVQNSQDKSIEKHGSSKIETMNKSPHI-SNCSVASDYLDLDKITVED 144
            LA  +K +  VT N +  Q+  ++K   S+         +  +C V ++ LD  K    +
Sbjct: 1125 LAPPIKPIKPVTRN-KAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRN 1183

Query: 145  DVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDED 204
                    RK  +      +  L + +      + +   +  +DS++ S      D+ + 
Sbjct: 1184 IKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQK 1243

Query: 205  F--SMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQ-SLPKK 261
               S R+    +    E   + PVE+K ++         +   + PA+ KS  Q S P  
Sbjct: 1244 PTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPAL 1303

Query: 262  VSLSSDTTRKP--LEIRSPSAESKKPKWVPPAASGGSRS 298
            V      T  P   E+   +    K K  PP  SG  +S
Sbjct: 1304 VIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQS 1342


>gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]
          Length = 888

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 54/224 (24%), Positives = 91/224 (40%), Gaps = 25/224 (11%)

Query: 34  KKSRTAPKELKQDKPKPNLNNLRKEEIPVQEKTPKKRMALDDKLYQRDLEVALALSVKEL 93
           +K +   KE +++K K       KE+  V E       A         +  +       +
Sbjct: 112 RKKKEKEKEKEKEKEKEKEREKEKEKATVSENVAASAAATTPATSPPAVNTS-----PSV 166

Query: 94  PTVTTNVQNSQDKSIEKHGSSKIETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQGKR 153
           PT TT  +       E+    K   + ++  + +     +  D+D    EDD        
Sbjct: 167 PTTTTATE-------EQVSEPKKWNLRRNRPLLDFVSMEELNDMDDYDSEDDNDWRPTVV 219

Query: 154 KAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVK 213
           K   ++A+Q+     EGSDGD  N+ + D   G D ED++D    E NDED S   S+  
Sbjct: 220 KRKGRSASQK-----EGSDGD--NEDDEDEGSGSD-EDEND----EGNDEDHSSPASE-G 266

Query: 214 EIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQS 257
             KKK+ KV S     +++  +    L  S  +  + +  +SQ+
Sbjct: 267 GCKKKKSKVLSRNSADDEELTNDSLTLSQSKSNEDSLILEKSQN 310



 Score = 35.8 bits (81), Expect = 0.055
 Identities = 27/99 (27%), Positives = 48/99 (48%), Gaps = 4/99 (4%)

Query: 177 NDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSK 236
           N  E +    E      +  E E+N E    +K K KE +K++ K K   ++KEK + S+
Sbjct: 83  NSAEEEVLSSEKQLIKMEKKEEEENGERPRKKKEKEKEKEKEKEKEKEREKEKEKATVSE 142

Query: 237 ---CNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKP 272
               +A  T+  ++P AV + S S+P   + + +   +P
Sbjct: 143 NVAASAAATTPATSPPAVNT-SPSVPTTTTATEEQVSEP 180



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 33/135 (24%), Positives = 55/135 (40%), Gaps = 15/135 (11%)

Query: 152 KRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSK 211
           KR+     AA     LLE  D DS++D+  DF  G+ S+ +     SED  +D       
Sbjct: 6   KRRQVKPLAAS----LLEALDYDSSDDS--DFKVGDASDSEGSGNGSEDASKDSGEGSCS 59

Query: 212 VKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRK 271
             E    E ++   ++ KE++ K+     V S         SE Q +  +     +   +
Sbjct: 60  DSEENILEEELNEDIKVKEEQLKNSAEEEVLS---------SEKQLIKMEKKEEEENGER 110

Query: 272 PLEIRSPSAESKKPK 286
           P + +    E +K K
Sbjct: 111 PRKKKEKEKEKEKEK 125


>gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]
          Length = 948

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 54/224 (24%), Positives = 91/224 (40%), Gaps = 25/224 (11%)

Query: 34  KKSRTAPKELKQDKPKPNLNNLRKEEIPVQEKTPKKRMALDDKLYQRDLEVALALSVKEL 93
           +K +   KE +++K K       KE+  V E       A         +  +       +
Sbjct: 112 RKKKEKEKEKEKEKEKEKEREKEKEKATVSENVAASAAATTPATSPPAVNTS-----PSV 166

Query: 94  PTVTTNVQNSQDKSIEKHGSSKIETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQGKR 153
           PT TT  +       E+    K   + ++  + +     +  D+D    EDD        
Sbjct: 167 PTTTTATE-------EQVSEPKKWNLRRNRPLLDFVSMEELNDMDDYDSEDDNDWRPTVV 219

Query: 154 KAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVK 213
           K   ++A+Q+     EGSDGD  N+ + D   G D ED++D    E NDED S   S+  
Sbjct: 220 KRKGRSASQK-----EGSDGD--NEDDEDEGSGSD-EDEND----EGNDEDHSSPASE-G 266

Query: 214 EIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQS 257
             KKK+ KV S     +++  +    L  S  +  + +  +SQ+
Sbjct: 267 GCKKKKSKVLSRNSADDEELTNDSLTLSQSKSNEDSLILEKSQN 310



 Score = 35.8 bits (81), Expect = 0.055
 Identities = 27/99 (27%), Positives = 48/99 (48%), Gaps = 4/99 (4%)

Query: 177 NDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSK 236
           N  E +    E      +  E E+N E    +K K KE +K++ K K   ++KEK + S+
Sbjct: 83  NSAEEEVLSSEKQLIKMEKKEEEENGERPRKKKEKEKEKEKEKEKEKEREKEKEKATVSE 142

Query: 237 ---CNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKP 272
               +A  T+  ++P AV + S S+P   + + +   +P
Sbjct: 143 NVAASAAATTPATSPPAVNT-SPSVPTTTTATEEQVSEP 180



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 33/135 (24%), Positives = 55/135 (40%), Gaps = 15/135 (11%)

Query: 152 KRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSK 211
           KR+     AA     LLE  D DS++D+  DF  G+ S+ +     SED  +D       
Sbjct: 6   KRRQVKPLAAS----LLEALDYDSSDDS--DFKVGDASDSEGSGNGSEDASKDSGEGSCS 59

Query: 212 VKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRK 271
             E    E ++   ++ KE++ K+     V S         SE Q +  +     +   +
Sbjct: 60  DSEENILEEELNEDIKVKEEQLKNSAEEEVLS---------SEKQLIKMEKKEEEENGER 110

Query: 272 PLEIRSPSAESKKPK 286
           P + +    E +K K
Sbjct: 111 PRKKKEKEKEKEKEK 125


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 66/260 (25%), Positives = 110/260 (42%), Gaps = 38/260 (14%)

Query: 36   SRTAPKELKQDKPKPNLNNLRKEEIPVQEKTPKKRMALDDKLYQRDLEVALALSVKELPT 95
            S  A +  + +K K    + +K+ + V+EK   KR +L     ++  ++  + S      
Sbjct: 1117 SSDAEESSEDNKKKKQRTSSKKKAVIVKEK---KRNSLRTSTKRKQADITSSSS----SD 1169

Query: 96   VTTNVQNS--QDKSIEKHGSSKIETMNKSPHISNCSVASDYLDLDK---ITVEDDVGGVQ 150
            +  + QNS  +  S E+      E +  S H   C  + D   L K   +TV+DD     
Sbjct: 1170 IEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEA-LSKSVPVTVDDDDDDND 1228

Query: 151  GKRKAASKAAAQQRKILLEGSDGDSANDTEPDFA-----------PGED-------SEDD 192
             + + A K   ++ K  L  SD D ++D EP+             PG++       SE D
Sbjct: 1229 PENRIAKKMLLEEIKANL-SSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESD 1287

Query: 193  SDFCESEDNDEDFSMRKSK--VKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAA 250
            SD  ES+       + + K  V + +  E K   P E KE K +++    V+S DS  + 
Sbjct: 1288 SDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNR--RKVSSEDSEDSD 1345

Query: 251  VKSESQSLPKKVSLSSDTTR 270
             +    S  ++VS S D  R
Sbjct: 1346 FQESGVS--EEVSESEDEQR 1363



 Score = 32.0 bits (71), Expect = 0.80
 Identities = 55/292 (18%), Positives = 108/292 (36%), Gaps = 18/292 (6%)

Query: 3   RPVRHKKPVNYSQFDHSDSDDDFVSATVPLNKKSRTAPKELKQDKPKPN-LNNLRKEEIP 61
           RP       + S  + +++  +    +VP+ KK +    +   D PKPN L   ++ E  
Sbjct: 628 RPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETV 687

Query: 62  VQEKTPKKRMALDDKLYQRDLEVALALSVKELPT--------VTTNVQNSQDKSIEKHGS 113
            Q     + +A+  ++ +     +    + E+ T         T   ++ + K   K  +
Sbjct: 688 DQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSST 747

Query: 114 SKIETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASK--AAAQQRKILLEGS 171
           S  +   K    +  S+ S      +    +    ++ + K+ SK  AA   +K +    
Sbjct: 748 SGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTK 807

Query: 172 DGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEK 231
           D DS+ D E     G D++   +   S++   D + RK + +     E  V       E 
Sbjct: 808 DFDSSED-EKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMEL 866

Query: 232 KSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESK 283
           + +      +     A A+     +   K+ S +S   RK  E +  S   K
Sbjct: 867 RDR------LPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLK 912



 Score = 30.4 bits (67), Expect = 2.3
 Identities = 46/224 (20%), Positives = 85/224 (37%), Gaps = 14/224 (6%)

Query: 21   SDDDFVSATVPLNKKSRTAPK--ELKQDKPKPNLNNLRKEEIPVQEKTPKKR-MALDDKL 77
            SD+D  S   P   K RT  +  E   D+   N  N   +    + K P+ R   L  KL
Sbjct: 1248 SDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKL 1307

Query: 78   YQRDLEVALALSVKELPTVTTNVQNSQDKSIEKHGSSKIETMNKSPHISNCSVASDYLDL 137
               D E       K         +N +  S E    S  +    S  +S         D 
Sbjct: 1308 TVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESE------DE 1361

Query: 138  DKITVEDDVGGVQGKRKAASKAAAQQRKILLE---GSDGDSANDTEPDFAPGEDSEDDSD 194
             +            + + + K   ++R+I ++    S+  S ++ E +    E+ E++ +
Sbjct: 1362 QRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEE 1421

Query: 195  FCESEDNDEDFSMRKSKVKEIKK--KEVKVKSPVEKKEKKSKSK 236
              E ED ++D        K+I+K  K+ K+++  +   K+ + +
Sbjct: 1422 EEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEER 1465


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 66/260 (25%), Positives = 110/260 (42%), Gaps = 38/260 (14%)

Query: 36   SRTAPKELKQDKPKPNLNNLRKEEIPVQEKTPKKRMALDDKLYQRDLEVALALSVKELPT 95
            S  A +  + +K K    + +K+ + V+EK   KR +L     ++  ++  + S      
Sbjct: 1155 SSDAEESSEDNKKKKQRTSSKKKAVIVKEK---KRNSLRTSTKRKQADITSSSS----SD 1207

Query: 96   VTTNVQNS--QDKSIEKHGSSKIETMNKSPHISNCSVASDYLDLDK---ITVEDDVGGVQ 150
            +  + QNS  +  S E+      E +  S H   C  + D   L K   +TV+DD     
Sbjct: 1208 IEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEA-LSKSVPVTVDDDDDDND 1266

Query: 151  GKRKAASKAAAQQRKILLEGSDGDSANDTEPDFA-----------PGED-------SEDD 192
             + + A K   ++ K  L  SD D ++D EP+             PG++       SE D
Sbjct: 1267 PENRIAKKMLLEEIKANL-SSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESD 1325

Query: 193  SDFCESEDNDEDFSMRKSK--VKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAA 250
            SD  ES+       + + K  V + +  E K   P E KE K +++    V+S DS  + 
Sbjct: 1326 SDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNR--RKVSSEDSEDSD 1383

Query: 251  VKSESQSLPKKVSLSSDTTR 270
             +    S  ++VS S D  R
Sbjct: 1384 FQESGVS--EEVSESEDEQR 1401



 Score = 32.0 bits (71), Expect = 0.80
 Identities = 55/292 (18%), Positives = 108/292 (36%), Gaps = 18/292 (6%)

Query: 3   RPVRHKKPVNYSQFDHSDSDDDFVSATVPLNKKSRTAPKELKQDKPKPN-LNNLRKEEIP 61
           RP       + S  + +++  +    +VP+ KK +    +   D PKPN L   ++ E  
Sbjct: 666 RPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETV 725

Query: 62  VQEKTPKKRMALDDKLYQRDLEVALALSVKELPT--------VTTNVQNSQDKSIEKHGS 113
            Q     + +A+  ++ +     +    + E+ T         T   ++ + K   K  +
Sbjct: 726 DQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSST 785

Query: 114 SKIETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASK--AAAQQRKILLEGS 171
           S  +   K    +  S+ S      +    +    ++ + K+ SK  AA   +K +    
Sbjct: 786 SGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTK 845

Query: 172 DGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEK 231
           D DS+ D E     G D++   +   S++   D + RK + +     E  V       E 
Sbjct: 846 DFDSSED-EKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMEL 904

Query: 232 KSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESK 283
           + +      +     A A+     +   K+ S +S   RK  E +  S   K
Sbjct: 905 RDR------LPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLK 950



 Score = 30.4 bits (67), Expect = 2.3
 Identities = 46/224 (20%), Positives = 85/224 (37%), Gaps = 14/224 (6%)

Query: 21   SDDDFVSATVPLNKKSRTAPK--ELKQDKPKPNLNNLRKEEIPVQEKTPKKR-MALDDKL 77
            SD+D  S   P   K RT  +  E   D+   N  N   +    + K P+ R   L  KL
Sbjct: 1286 SDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKL 1345

Query: 78   YQRDLEVALALSVKELPTVTTNVQNSQDKSIEKHGSSKIETMNKSPHISNCSVASDYLDL 137
               D E       K         +N +  S E    S  +    S  +S         D 
Sbjct: 1346 TVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESE------DE 1399

Query: 138  DKITVEDDVGGVQGKRKAASKAAAQQRKILLE---GSDGDSANDTEPDFAPGEDSEDDSD 194
             +            + + + K   ++R+I ++    S+  S ++ E +    E+ E++ +
Sbjct: 1400 QRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEE 1459

Query: 195  FCESEDNDEDFSMRKSKVKEIKK--KEVKVKSPVEKKEKKSKSK 236
              E ED ++D        K+I+K  K+ K+++  +   K+ + +
Sbjct: 1460 EEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEER 1503


>gi|4507241 structure specific recognition protein 1 [Homo sapiens]
          Length = 709

 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 34/132 (25%), Positives = 61/132 (46%), Gaps = 20/132 (15%)

Query: 171 SDGDSANDTEPDFAPGEDSEDDSD------FCESEDNDEDFSMRKSKVKEIKKKEV---- 220
           S  DS  +T+  F PGE+ ED ++         S  N+ D    + K K++KK ++    
Sbjct: 470 SSDDSGEETDESFNPGEEEEDVAEEFDSNASASSSSNEGDSDRDEKKRKQLKKAKMAKDR 529

Query: 221 -KVKSPVEKKEKKS----KSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEI 275
              K PVE K+ K     K   +A +  ++++   +KS+   +       +D ++K  EI
Sbjct: 530 KSRKKPVEVKKGKDPNAPKRPMSAYMLWLNASREKIKSDHPGIS-----ITDLSKKAGEI 584

Query: 276 RSPSAESKKPKW 287
               ++ KK +W
Sbjct: 585 WKGMSKEKKEEW 596


>gi|55769587 probable nucleolar complex protein 14 [Homo sapiens]
          Length = 857

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 48/218 (22%), Positives = 89/218 (40%), Gaps = 26/218 (11%)

Query: 22  DDDFVSATVPLNKKSRTAPKELKQDKPKPNLNNLRKEEIPVQEKT-PKKRMALDDKLYQR 80
           D D+      L+ K+  +    K++KPKP+  ++   E+  + K  P  RM  + +L + 
Sbjct: 222 DQDWKEIQTLLSHKTPKSENRDKKEKPKPDAYDMMVRELGFEMKAQPSNRMKTEAELAKE 281

Query: 81  DLEVALALSVKELPTVTTNVQNSQDKSIEKHGSSKIETMNKSPHISNCSVASDYLDLDKI 140
           + E    L  + L  +   +   +D++++K      + +N    +             K+
Sbjct: 282 EQEHLRKLEAERLRRM---LGKDEDENVKKPKHMSADDLNDGFVLDKDDRRLLSYKDGKM 338

Query: 141 TVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDD---SDFCE 197
            VE+DV   Q K                E SD +S N+ E D + GED+E+        +
Sbjct: 339 NVEEDVQEEQSK----------------EASDPES-NEEEGDSSGGEDTEESDSPDSHLD 381

Query: 198 SEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKKSKS 235
            E N E     +   KE  +++   K  +  KE+  K+
Sbjct: 382 LESNVESEEENEKPAKE--QRQTPGKGLISGKERAGKA 417


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
           [Homo sapiens]
          Length = 651

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 63/284 (22%), Positives = 112/284 (39%), Gaps = 22/284 (7%)

Query: 8   KKPVNYSQFDHSDSDDDFVSATVPLNKKSRTAPKELKQDKPKPNLNNLR-KEEIPVQEKT 66
           K P+  S  +         S T P ++ S+T  K   Q   K + N+ +   E    +  
Sbjct: 160 KTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNN 219

Query: 67  PKKRM----ALDDKLYQRDLEVALALSVKELPTVTTNVQNSQDKSIEKHGSSKIETMNKS 122
           PKK +      +D + +   E +L +    L      V  S D+SI      +  + N S
Sbjct: 220 PKKDLKRSKTSNDPISEICSENSLNVDFLML------VGQSDDESINFDAWLRNYSQNNS 273

Query: 123 PHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPD 182
            + S        L   K T +D     +    A S+ +   +K   +       +D + D
Sbjct: 274 KNYS--------LKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKD 325

Query: 183 FAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALVT 242
                +S  D++  +S+D  +D    K K+K+  KK+   K P E  + +S    +A   
Sbjct: 326 VKKDTES-TDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYP-ESTDTESGDAKDARND 383

Query: 243 SVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESKKPK 286
           S +   A+   + +   KK++ S+D +   LE +    + KK K
Sbjct: 384 SRNLKKASKNDDKKKDAKKITFSTD-SESELESKESQKDEKKDK 426



 Score = 30.4 bits (67), Expect = 2.3
 Identities = 47/231 (20%), Positives = 89/231 (38%), Gaps = 10/231 (4%)

Query: 8   KKPVNYSQFDHSDSDDDFVSATVPLNKKSRTAPKELKQDKPKPNLNNLRKEEIPVQEKTP 67
           KK  +    D  D+  D  S  V  N K     K++K+D    +  +   ++     K  
Sbjct: 293 KKSSDAESEDSKDAKKD--SKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKD 350

Query: 68  KKRMALDDKLYQRDLEVALALSVKELPTVTTNVQNSQDKSIEKHGSSKIETMNKSPHISN 127
           KK++  DDK  ++D +       +   T + + +++++ S     +SK +   K      
Sbjct: 351 KKKLKKDDK--KKDTKKY----PESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKIT 404

Query: 128 CSVASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQRKILLEGSD--GDSANDTEPDFAP 185
            S  S+     K + +D+    +  +    K+     +     S+  GDS    + +   
Sbjct: 405 FSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKG 464

Query: 186 GEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSK 236
            +DS+ D    +++ N E   M      +  KK  K K   +K  KK   K
Sbjct: 465 KKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARK 515


>gi|217330641 IWS1 homolog [Homo sapiens]
          Length = 819

 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 48/240 (20%), Positives = 97/240 (40%), Gaps = 10/240 (4%)

Query: 35  KSRTAPKELKQDKPKPNLNNLRKEEIP-------VQEKTPKKRMALDDKLYQRDLEVALA 87
           K R +  E  ++ PKP +++   EE P         E+ PK R++ D +        A  
Sbjct: 205 KPRMSDSE-SEELPKPQVSDSESEEPPRHQASDSENEELPKPRIS-DSESEDPPRHQASD 262

Query: 88  LSVKELPTVTTNVQNSQDKSIEKHGSSKIETMNKSPHISNCSVASDYLDLDKITVEDDVG 147
              +ELP    +   S+D    +   S+ E + K P +S+             +  +D  
Sbjct: 263 SENEELPKPRISDSESEDPPRNQASDSENEELPK-PRVSDSESEGPQKGPASDSETEDAS 321

Query: 148 GVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSM 207
             + K ++   +  + +    E  +    +D+  D      S+ + +  + +  D D   
Sbjct: 322 RHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDE 381

Query: 208 RKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSD 267
           ++ + +++ K++  V S  E +EK S  K   +  + DS   AV  +S    K ++  S+
Sbjct: 382 KEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVSDKSGKREKTIASDSE 441



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 55/222 (24%), Positives = 90/222 (40%), Gaps = 27/222 (12%)

Query: 45  QDKPKPNLNNLRKEEIPVQEKTPKKRMALDDKLYQRDLEVALALSVKELPTVTTNVQNSQ 104
           ++ PKP +++   EE+P       K    D +  +     A     +ELP    +   S+
Sbjct: 201 EEPPKPRMSDSESEELP-------KPQVSDSESEEPPRHQASDSENEELPKPRISDSESE 253

Query: 105 DKSIEKHGSSKIETMNKSPHIS---------NCSVASDYLDLDKITVED-DVGGVQGKRK 154
           D    +   S+ E + K P IS         N +  S+  +L K  V D +  G Q    
Sbjct: 254 DPPRHQASDSENEELPK-PRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPA 312

Query: 155 AASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKE 214
           + S+     R      SD DS  + +     GED+E  +D   S+ + +      S  +E
Sbjct: 313 SDSETEDASRHKQKPESDDDSDRENK-----GEDTEMQNDSFHSDSHMDRKKFHSSDSEE 367

Query: 215 IKKKEVKVKSPVEKK----EKKSKSKCNALVTSVDSAPAAVK 252
            + K+ K+ S  ++K    EK +K K   L  S D   A+ K
Sbjct: 368 EEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAK 409



 Score = 32.3 bits (72), Expect = 0.61
 Identities = 46/206 (22%), Positives = 82/206 (39%), Gaps = 23/206 (11%)

Query: 103 SQDKSIEKHG----SSKIETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASK 158
           S   S+E+H     S + + + K  H+++ S   + L+L+    E +    Q    + S+
Sbjct: 40  SDTGSVERHSENETSDREDGLPKGHHVTD-SENDEPLNLNASDSESEELHRQKDSDSESE 98

Query: 159 AAAQQRKILLEGSD----GDSANDTEPDFAPGEDSEDDS--DFCESEDNDEDFSMRK--- 209
             A+      E  D    G  +   E    PG DSE++   +   S+  +ED        
Sbjct: 99  ERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENEELLNGHASDSENEDVGKHPASD 158

Query: 210 SKVKEIKKK-------EVKVKSPVEKKEKKSKSKCNALVTSVDSAPAA--VKSESQSLPK 260
           S+++E++K        E  +K  +   E +   +  A  +  +  P      SES+ LPK
Sbjct: 159 SEIEELQKSPASDSETEDALKPQISDSESEEPPRHQASDSENEEPPKPRMSDSESEELPK 218

Query: 261 KVSLSSDTTRKPLEIRSPSAESKKPK 286
                S++   P    S S   + PK
Sbjct: 219 PQVSDSESEEPPRHQASDSENEELPK 244



 Score = 29.6 bits (65), Expect = 4.0
 Identities = 41/199 (20%), Positives = 82/199 (41%), Gaps = 32/199 (16%)

Query: 18  HSDSDDDFVSATVPLNKKSRTAPKELKQDKPKPNLNNLRKEEIPVQEKTPKKRMALDDKL 77
           HSDS  D         KK  ++  E ++ K K  +++   E+   +EK  K++ A+    
Sbjct: 350 HSDSHMD--------RKKFHSSDSEEEEHK-KQKMDSDEDEKEGEEEKVAKRKAAV---- 396

Query: 78  YQRDLEVALALSVKELPTVTTNVQNSQDKSIEKHGSSKIETMNKSPHISNCSVASDYLDL 137
              D E     S K+   V+    +  D   +K G  +    + S   +   ++      
Sbjct: 397 -LSDSEDEEKASAKKSRVVSDADDSDSDAVSDKSGKREKTIASDSEEEAGKELS------ 449

Query: 138 DKITVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPG-----EDSEDD 192
           DK   E D+ G       +   +  + + L+    G+S ++ E +F        E+ + +
Sbjct: 450 DKKNEEKDLFG-------SDSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKGE 502

Query: 193 SDFCESEDNDEDFSMRKSK 211
           +   E+ED+D D ++++ K
Sbjct: 503 TQVKEAEDSDSDDNIKRGK 521


>gi|34482047 adaptor-related protein complex 3, beta 2 subunit [Homo
           sapiens]
          Length = 1082

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 27/116 (23%), Positives = 52/116 (44%)

Query: 169 EGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEK 228
           E +D D  +++E D     +S       ES++ D+D    K +  E ++ E   K   +K
Sbjct: 689 ESADSDPESESESDSKSSSESGSGESSSESDNEDQDEDEEKGRGSESEQSEEDGKRKTKK 748

Query: 229 KEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESKK 284
           K  + K + ++     DS+ ++ +SE  S  ++  L   +  +     S SA + K
Sbjct: 749 KVPERKGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPSSKSAPATK 804



 Score = 28.9 bits (63), Expect = 6.8
 Identities = 32/138 (23%), Positives = 55/138 (39%), Gaps = 13/138 (9%)

Query: 171 SDGDSANDTEP---DFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVE 227
           S+ DS + +E    + +   D+ED     + ED ++       + +E  K++ K K P  
Sbjct: 699 SESDSKSSSESGSGESSSESDNED-----QDEDEEKGRGSESEQSEEDGKRKTKKKVPER 753

Query: 228 KKEKKSKSKCNALVTSVDSAPAAVKSESQSL-----PKKVSLSSDTTRKPLEIRSPSAES 282
           K E  S  + +   +S   +    +SE + L      +K   SS +     EI     E 
Sbjct: 754 KGEASSSDEGSDSSSSSSESEMTSESEEEQLEPASWSRKTPPSSKSAPATKEISLLDLED 813

Query: 283 KKPKWVPPAASGGSRSSS 300
             P  V P +     S+S
Sbjct: 814 FTPPSVQPVSPPAIVSTS 831


>gi|48255931 hepatoma-derived growth factor-related protein 2
           isoform 1 [Homo sapiens]
          Length = 671

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 48/193 (24%), Positives = 80/193 (41%), Gaps = 26/193 (13%)

Query: 129 SVASDYLDLDKITVED-DVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGE 187
           + ASD ++ D  + +  D  G+  KRK  +   +  ++     SD D A+      +P E
Sbjct: 134 TAASDRMESDSDSDKSSDNSGL--KRKTPALKMSVSKRARKASSDLDQAS-----VSPSE 186

Query: 188 DSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPV---EKKEKKSKSKCNALVTSV 244
           +   +S     + +D+DF+  K       ++      P+   +KK+  S S  ++   S 
Sbjct: 187 EENSESSSESEKTSDQDFTPEKKAAVRAPRR-----GPLGGRKKKKAPSASDSDSKADSD 241

Query: 245 DSAP---AAVKSESQSLPKKVSLSSDTT-------RKPLEIRSPSAESKKPKWVPPAASG 294
            + P   A  +S S S     S  SD +       RKP E   P    +KPK   P +S 
Sbjct: 242 GAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSSS 301

Query: 295 GSRSSSSPLVVVS 307
            S S S  +  +S
Sbjct: 302 SSDSDSDEVDRIS 314



 Score = 35.8 bits (81), Expect = 0.055
 Identities = 52/206 (25%), Positives = 77/206 (37%), Gaps = 55/206 (26%)

Query: 171 SDGDSANDTEPD-----------FAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKE 219
           +DG  A++ + D            A  +  E DSD  +S DN             +K+K 
Sbjct: 111 ADGSDADEDDEDRGVMAVTAVTATAASDRMESDSDSDKSSDNSG-----------LKRKT 159

Query: 220 VKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSP- 278
             +K  V K+ +K+ S  +    S         SES S  +K S    T  K   +R+P 
Sbjct: 160 PALKMSVSKRARKASSDLDQASVSPSEEE---NSESSSESEKTSDQDFTPEKKAAVRAPR 216

Query: 279 ----------------------SAESKKPKWVPPA--ASGGSRSSSSPLVVVSVKSPNQS 314
                                  ++  KP+ V  A  AS  S SSSS    VSVK P + 
Sbjct: 217 RGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRG 276

Query: 315 LR-----LGLSRLARVKPLHPNATST 335
            +     L   R  + KP  P ++S+
Sbjct: 277 RKPAEKPLPKPRGRKPKPERPPSSSS 302


>gi|14249158 hepatoma-derived growth factor-related protein 2
           isoform 2 [Homo sapiens]
          Length = 670

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 48/193 (24%), Positives = 80/193 (41%), Gaps = 26/193 (13%)

Query: 129 SVASDYLDLDKITVED-DVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGE 187
           + ASD ++ D  + +  D  G+  KRK  +   +  ++     SD D A+      +P E
Sbjct: 134 TAASDRMESDSDSDKSSDNSGL--KRKTPALKMSVSKRARKASSDLDQAS-----VSPSE 186

Query: 188 DSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPV---EKKEKKSKSKCNALVTSV 244
           +   +S     + +D+DF+  K       ++      P+   +KK+  S S  ++   S 
Sbjct: 187 EENSESSSESEKTSDQDFTPEKKAAVRAPRR-----GPLGGRKKKKAPSASDSDSKADSD 241

Query: 245 DSAP---AAVKSESQSLPKKVSLSSDTT-------RKPLEIRSPSAESKKPKWVPPAASG 294
            + P   A  +S S S     S  SD +       RKP E   P    +KPK   P +S 
Sbjct: 242 GAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSSS 301

Query: 295 GSRSSSSPLVVVS 307
            S S S  +  +S
Sbjct: 302 SSDSDSDEVDRIS 314



 Score = 35.8 bits (81), Expect = 0.055
 Identities = 52/206 (25%), Positives = 77/206 (37%), Gaps = 55/206 (26%)

Query: 171 SDGDSANDTEPD-----------FAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKE 219
           +DG  A++ + D            A  +  E DSD  +S DN             +K+K 
Sbjct: 111 ADGSDADEDDEDRGVMAVTAVTATAASDRMESDSDSDKSSDNSG-----------LKRKT 159

Query: 220 VKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSP- 278
             +K  V K+ +K+ S  +    S         SES S  +K S    T  K   +R+P 
Sbjct: 160 PALKMSVSKRARKASSDLDQASVSPSEEE---NSESSSESEKTSDQDFTPEKKAAVRAPR 216

Query: 279 ----------------------SAESKKPKWVPPA--ASGGSRSSSSPLVVVSVKSPNQS 314
                                  ++  KP+ V  A  AS  S SSSS    VSVK P + 
Sbjct: 217 RGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRG 276

Query: 315 LR-----LGLSRLARVKPLHPNATST 335
            +     L   R  + KP  P ++S+
Sbjct: 277 RKPAEKPLPKPRGRKPKPERPPSSSS 302


>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
          Length = 248

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 42/168 (25%), Positives = 67/168 (39%), Gaps = 3/168 (1%)

Query: 133 DYLDLDKITVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEPDFAPGEDSEDD 192
           DYL+  + T E+    ++ K K  SKA A+  + + E    +     E   +  E S   
Sbjct: 32  DYLNRPRPTWEEVKKQLENK-KTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKK 90

Query: 193 SDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSAPAAVK 252
            +  +        S   S   +        +   +K+ K+ K K N    S  S+    +
Sbjct: 91  RERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESE 150

Query: 253 SESQSLPKKVSLSSDTTRKPLEIRSPSAESKK--PKWVPPAASGGSRS 298
           SES+   KK   S D T K  ++RS S + KK  P   P ++   S S
Sbjct: 151 SESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSES 198



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 47/201 (23%), Positives = 84/201 (41%), Gaps = 25/201 (12%)

Query: 41  KELKQDKPKPNLNNLRKEEIPVQEKTPKKRMALDDKLYQRDLEVALALSVKELPTVTTNV 100
           +E   +  K  L   R++ +   E + KKR    ++  +R  +   + S       +++ 
Sbjct: 62  EEKMNENWKKELEKSREKLLSGNESSSKKR----ERKKKRKKKSCRSSSSSSSSDSSSSS 117

Query: 101 QNSQDKSIEKHGSSKIETMNKSPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASKAA 160
            +S+D+  +K G  + +  N+S   S  S      +  +            K+K  SK  
Sbjct: 118 SDSEDEE-KKQGKRRKKKKNRSYKSSQSSTHESESESKESV----------KKKKKSKDE 166

Query: 161 AQQRKILLEGSDGDSANDTEPDFAP-GEDSEDDSDFCES-----EDNDEDFSMRKSKVKE 214
            ++ K +   S       + PD  P   +S  +SD+ E      +   E+    K KVK+
Sbjct: 167 TEKEKDVRSLSK--KRKKSYPDDKPLSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKK 224

Query: 215 IKKKEVKVKSPVEKKEKKSKS 235
            KKK+ K  S  +KK+KKS S
Sbjct: 225 KKKKQHKKHS--KKKKKKSGS 243


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 77/324 (23%), Positives = 108/324 (33%), Gaps = 60/324 (18%)

Query: 19  SDSDDDFVSATVP-LNKKSRTAPKELKQDK---PKP-------------NLNNLRKEEIP 61
           SDSD D  S   P  N+K +  P  +K      PKP             + ++       
Sbjct: 167 SDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSS 226

Query: 62  VQEKTPKKRMALDDKLYQRDLEVALALSVKELPTVTTNVQNSQDKSIEKHGSSKIETMNK 121
             +   +K  A   K   +   VA A  VK   T T    +S+D S ++    K    NK
Sbjct: 227 SDDSEEEKAAATPKKTVPKKQVVAKA-PVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNK 285

Query: 122 SPHISNCSVASDYLDLDKITVEDDVGGVQGKRKAASKAAAQQRKILLEGSDGDSANDTEP 181
               S+    S       +       G Q  +KA  K   QQ     E S  +S + +E 
Sbjct: 286 PGPYSSVPPPSAPPPKKSL-------GTQPPKKAVEK---QQPVESSEDSSDESDSSSEE 335

Query: 182 DFAP-------------------GEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKV 222
           +  P                    E S D SD   SED++       +      K  V  
Sbjct: 336 EKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTT 395

Query: 223 KSPVEKKEKKSKSKCNA----LVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSP 278
           KSP  K     K         L    DS+ +  +S S           + T+K +    P
Sbjct: 396 KSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSS--------EEEKTKKMVATTKP 447

Query: 279 SAESKKPKWVP-PAASGGSRSSSS 301
            A +K    +P   A  GSR SSS
Sbjct: 448 KATAKAALSLPAKQAPQGSRDSSS 471



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 35/121 (28%), Positives = 50/121 (41%), Gaps = 12/121 (9%)

Query: 181 PDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNAL 240
           P  A  + SE  S    S+D+DE+   ++   K +K +    K+P  KK K S S  ++ 
Sbjct: 116 PGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAP-PKKAKSSDSDSDS- 173

Query: 241 VTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESKKPKWVPPAASGGSRSSS 300
            +S D  P     + +  P  V   +    KP       A  K       AAS  S SSS
Sbjct: 174 -SSEDEPPK--NQKPKITPVTVKAQTKAPPKPARAAPKIANGK-------AASSSSSSSS 223

Query: 301 S 301
           S
Sbjct: 224 S 224



 Score = 32.7 bits (73), Expect = 0.47
 Identities = 44/205 (21%), Positives = 69/205 (33%), Gaps = 52/205 (25%)

Query: 150 QGKRKAASKAAAQQRKILLEGSDGDSANDTEPD--------------------------- 182
           +G +  A  A A  +K     SD DS+++ EP                            
Sbjct: 148 KGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAP 207

Query: 183 -FAPGE--DSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPV------------- 226
             A G+   S   S    S D+ E+     +  K + KK+V  K+PV             
Sbjct: 208 KIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSS 267

Query: 227 -------EKKEKKSKSKCNALVTSV--DSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRS 277
                  E+++KK         +SV   SAP   KS     PKK            +   
Sbjct: 268 EDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSD 327

Query: 278 PSAESKKPKWVPPAASGGSRSSSSP 302
            S  S + +  PP  +  S++++ P
Sbjct: 328 ESDSSSEEEKKPPTKAVVSKATTKP 352



 Score = 30.0 bits (66), Expect = 3.0
 Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 5/76 (6%)

Query: 188 DSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEKKEKKSKSKCNALVTSVDSA 247
           DS  DSD   SE+ +E     K+    +KKK  KV       +  S  K  A  ++  S+
Sbjct: 468 DSSSDSDSSSSEEEEE-----KTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSS 522

Query: 248 PAAVKSESQSLPKKVS 263
             + + E + L  K S
Sbjct: 523 DDSSEEEEEKLKGKGS 538


>gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens]
          Length = 871

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 33/135 (24%), Positives = 57/135 (42%), Gaps = 6/135 (4%)

Query: 169 EGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEK 228
           EG  G    D E      ++ ++D    E++ +++D    K+K  E    + + K   EK
Sbjct: 288 EGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDD----KTKKSEGDGDKEEKKEDSEK 343

Query: 229 KEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESKKPKWV 288
           + KKS  K N   +  DS      SES+S  +  S  ++  ++  E      + K+ +W 
Sbjct: 344 EAKKSSKKRNRKHSGDDSFDEGSVSESES--ESESGQAEEEKEEAEALKEKEKPKEEEWE 401

Query: 289 PPAASGGSRSSSSPL 303
            P  + G      PL
Sbjct: 402 KPKDAAGLECKPRPL 416


>gi|192807332 arsenate resistance protein 2 isoform c [Homo sapiens]
          Length = 875

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 33/135 (24%), Positives = 57/135 (42%), Gaps = 6/135 (4%)

Query: 169 EGSDGDSANDTEPDFAPGEDSEDDSDFCESEDNDEDFSMRKSKVKEIKKKEVKVKSPVEK 228
           EG  G    D E      ++ ++D    E++ +++D    K+K  E    + + K   EK
Sbjct: 288 EGRAGAGLGDGERKTNDKDEKKEDGKQAENDSSNDD----KTKKSEGDGDKEEKKEDSEK 343

Query: 229 KEKKSKSKCNALVTSVDSAPAAVKSESQSLPKKVSLSSDTTRKPLEIRSPSAESKKPKWV 288
           + KKS  K N   +  DS      SES+S  +  S  ++  ++  E      + K+ +W 
Sbjct: 344 EAKKSSKKRNRKHSGDDSFDEGSVSESES--ESESGQAEEEKEEAEALKEKEKPKEEEWE 401

Query: 289 PPAASGGSRSSSSPL 303
            P  + G      PL
Sbjct: 402 KPKDAAGLECKPRPL 416


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.304    0.122    0.327 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,981,551
Number of Sequences: 37866
Number of extensions: 610105
Number of successful extensions: 5166
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 112
Number of HSP's successfully gapped in prelim test: 396
Number of HSP's that attempted gapping in prelim test: 3597
Number of HSP's gapped (non-prelim): 1355
length of query: 335
length of database: 18,247,518
effective HSP length: 103
effective length of query: 232
effective length of database: 14,347,320
effective search space: 3328578240
effective search space used: 3328578240
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.