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Search of human proteins with 5453629
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5453629 dynactin 2 [Homo sapiens]
(406 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5453629 dynactin 2 [Homo sapiens] 786 0.0
gi|38044112 restin isoform b [Homo sapiens] 43 6e-04
gi|4506751 restin isoform a [Homo sapiens] 43 6e-04
gi|7662230 ring finger protein 40 [Homo sapiens] 41 0.002
gi|71061468 centromere protein E [Homo sapiens] 40 0.004
gi|5032281 dystrophin Dp427c isoform [Homo sapiens] 40 0.005
gi|5032307 dystrophin Dp140c isoform [Homo sapiens] 40 0.005
gi|5032291 dystrophin Dp260-2 isoform [Homo sapiens] 40 0.005
gi|150036268 dystrophin Dp260-1 isoform [Homo sapiens] 40 0.005
gi|5032315 dystrophin Dp427p2 isoform [Homo sapiens] 40 0.005
gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens] 40 0.005
gi|5032313 dystrophin Dp140bc isoform [Homo sapiens] 40 0.005
gi|5032311 dystrophin Dp140ab isoform [Homo sapiens] 40 0.005
gi|5032309 dystrophin Dp140b isoform [Homo sapiens] 40 0.005
gi|5032293 dystrophin Dp140 isoform [Homo sapiens] 40 0.005
gi|5032285 dystrophin Dp427l isoform [Homo sapiens] 40 0.005
gi|5032283 dystrophin Dp427m isoform [Homo sapiens] 40 0.005
gi|88196790 coiled-coil domain containing 88 [Homo sapiens] 39 0.006
gi|81295809 pericentrin [Homo sapiens] 39 0.008
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 39 0.008
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 37 0.032
gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens] 37 0.032
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 37 0.032
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 37 0.032
gi|46593000 GRIP1 associated protein 1 isoform 2 [Homo sapiens] 37 0.042
gi|19913410 major vault protein [Homo sapiens] 36 0.071
gi|19913412 major vault protein [Homo sapiens] 36 0.071
gi|10337581 type I hair keratin 3B [Homo sapiens] 35 0.093
gi|223278353 C-type lectin domain family 4, member M isoform 3 [... 35 0.093
gi|42542390 C-type lectin domain family 4, member M isoform 1 [H... 35 0.093
>gi|5453629 dynactin 2 [Homo sapiens]
Length = 406
Score = 786 bits (2030), Expect = 0.0
Identities = 406/406 (100%), Positives = 406/406 (100%)
Query: 1 MADPKYADLPGIARNEPDVYETSDLPEDDQAEFDAFAQELEELTSTSVEHIIVNPNAAYD 60
MADPKYADLPGIARNEPDVYETSDLPEDDQAEFDAFAQELEELTSTSVEHIIVNPNAAYD
Sbjct: 1 MADPKYADLPGIARNEPDVYETSDLPEDDQAEFDAFAQELEELTSTSVEHIIVNPNAAYD 60
Query: 61 KFKDKRVGTKGLDFSDRIGKTKRTGYESGEYEMLGEGLGVKETPQQKYQRLLHEVQELTT 120
KFKDKRVGTKGLDFSDRIGKTKRTGYESGEYEMLGEGLGVKETPQQKYQRLLHEVQELTT
Sbjct: 61 KFKDKRVGTKGLDFSDRIGKTKRTGYESGEYEMLGEGLGVKETPQQKYQRLLHEVQELTT 120
Query: 121 EVEKIKTTVKESATEEKLTPVLLAKQLAALKQQLVASHLEKLLGPDAAINLTDPDGALAK 180
EVEKIKTTVKESATEEKLTPVLLAKQLAALKQQLVASHLEKLLGPDAAINLTDPDGALAK
Sbjct: 121 EVEKIKTTVKESATEEKLTPVLLAKQLAALKQQLVASHLEKLLGPDAAINLTDPDGALAK 180
Query: 181 RLLLQLEATKNSKGGSGGKTTGTPPDSSLVTYELHSRPEQDKFSQAAKVAELEKRLTELE 240
RLLLQLEATKNSKGGSGGKTTGTPPDSSLVTYELHSRPEQDKFSQAAKVAELEKRLTELE
Sbjct: 181 RLLLQLEATKNSKGGSGGKTTGTPPDSSLVTYELHSRPEQDKFSQAAKVAELEKRLTELE 240
Query: 241 TAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQVEARLQSVLGKVNEIAK 300
TAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQVEARLQSVLGKVNEIAK
Sbjct: 241 TAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQVEARLQSVLGKVNEIAK 300
Query: 301 HKASVEDADTQSKVHQLYETIQRWSPIASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDT 360
HKASVEDADTQSKVHQLYETIQRWSPIASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDT
Sbjct: 301 HKASVEDADTQSKVHQLYETIQRWSPIASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDT 360
Query: 361 TQQMIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMKKLGK 406
TQQMIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMKKLGK
Sbjct: 361 TQQMIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMKKLGK 406
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 42.7 bits (99), Expect = 6e-04
Identities = 79/360 (21%), Positives = 140/360 (38%), Gaps = 50/360 (13%)
Query: 90 EYEMLGEGLGVKETPQQKYQRLLHEVQE-LTTEVEKIKTTVKESATEEKLTPVLLAKQLA 148
E L E G +E QK + L+ E L+ E E +K+ ++ + E L +L
Sbjct: 523 EITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKL- 581
Query: 149 ALKQQLVASHLEKL----------LGPDAAINLTDPDGALAKRLLLQLEATKNSKGGSGG 198
+ +ASH + + LG + A + + K L +N +
Sbjct: 582 ---ETAIASHQQAMEELKVSFSKGLGTETA-EFAELKTQIEKMRLDYQHEIENLQNQQDS 637
Query: 199 KTTGTPPDSSLVTYELHSRPEQDKFSQAAKVAELEK----RLTELETAVRCDQDAQNPLS 254
+ + + +L ++ + S A ++L+K L E+E + Q+A+ +
Sbjct: 638 ERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVK 697
Query: 255 A--GLQGACLMET--VELLQAKVSALDLAVLDQVEARLQSVLGKVNEIAKHKASVEDADT 310
LQ C +T ++ +++ A + +LD R S GK +E+ K + +E A+
Sbjct: 698 ELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGK-SEMKKLRQQLEAAEK 756
Query: 311 QSKVHQLYETIQRWSPIASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIANSLK 370
Q K H E S +S EL R + + L E + Q+ L+ Q++
Sbjct: 757 QIK-HLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFA 815
Query: 371 DNTTLLTQVQTTM------------------------RENLATVEGNFASIDERMKKLGK 406
+ + VQ +M RENLA +E F DER ++L K
Sbjct: 816 EASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIK 875
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 42.7 bits (99), Expect = 6e-04
Identities = 79/360 (21%), Positives = 140/360 (38%), Gaps = 50/360 (13%)
Query: 90 EYEMLGEGLGVKETPQQKYQRLLHEVQE-LTTEVEKIKTTVKESATEEKLTPVLLAKQLA 148
E L E G +E QK + L+ E L+ E E +K+ ++ + E L +L
Sbjct: 558 EITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKL- 616
Query: 149 ALKQQLVASHLEKL----------LGPDAAINLTDPDGALAKRLLLQLEATKNSKGGSGG 198
+ +ASH + + LG + A + + K L +N +
Sbjct: 617 ---ETAIASHQQAMEELKVSFSKGLGTETA-EFAELKTQIEKMRLDYQHEIENLQNQQDS 672
Query: 199 KTTGTPPDSSLVTYELHSRPEQDKFSQAAKVAELEK----RLTELETAVRCDQDAQNPLS 254
+ + + +L ++ + S A ++L+K L E+E + Q+A+ +
Sbjct: 673 ERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVK 732
Query: 255 A--GLQGACLMET--VELLQAKVSALDLAVLDQVEARLQSVLGKVNEIAKHKASVEDADT 310
LQ C +T ++ +++ A + +LD R S GK +E+ K + +E A+
Sbjct: 733 ELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGK-SEMKKLRQQLEAAEK 791
Query: 311 QSKVHQLYETIQRWSPIASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIANSLK 370
Q K H E S +S EL R + + L E + Q+ L+ Q++
Sbjct: 792 QIK-HLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFA 850
Query: 371 DNTTLLTQVQTTM------------------------RENLATVEGNFASIDERMKKLGK 406
+ + VQ +M RENLA +E F DER ++L K
Sbjct: 851 EASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIK 910
>gi|7662230 ring finger protein 40 [Homo sapiens]
Length = 1001
Score = 40.8 bits (94), Expect = 0.002
Identities = 66/274 (24%), Positives = 115/274 (41%), Gaps = 31/274 (11%)
Query: 105 QQKYQRLLHEVQELTTEVEKIKTTVKESATEEKLTPVLLAKQLAALKQQLVASHLEKLLG 164
Q+K+ R+ E EL +V +T V E T + + K ++Q + HL + L
Sbjct: 248 QEKHHRISLEYSELQDKVTSAETKVLEMETTVEDLQWDIEK--LRKREQKLNKHLAEAL- 304
Query: 165 PDAAINLTDPDGALAKRLLLQLEATKNSKGGSGGKTTGTPPDSSLVTYELHSRPEQDKFS 224
++L + +S G GG+ T + ++ EL E+++
Sbjct: 305 ---------------EQLNSGYYVSGSSSGFQGGQITLSMQKFEMLNAEL----EENQEL 345
Query: 225 QAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVE--LLQAKVSAL---DLA 279
+++AELEK EL+ AVR ++ + L + L + ET E +LQA+ S L L
Sbjct: 346 ANSRMAELEKLQAELQGAVRTNERLKVALRS-LPEEVVRETGEYRMLQAQFSLLYNESLQ 404
Query: 280 VLDQVEARLQSVLGKVNEIAKHKASVEDADTQSKVHQLYETIQRWSPIASTLPELVQRLV 339
V Q++ +L N +H +E + + E IQ +A E +
Sbjct: 405 VKTQLDEARGLLLATKNSHLRHIEHMESDELGLQKKLRTEVIQLEDTLAQVRKEYEMLRI 464
Query: 340 TIKQ---LHEQAMQFGQLLTHLDTTQQMIANSLK 370
+Q +EQA + + HL ++ Q + LK
Sbjct: 465 EFEQNLAANEQAGPINREMRHLISSLQNHNHQLK 498
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 40.0 bits (92), Expect = 0.004
Identities = 58/292 (19%), Positives = 127/292 (43%), Gaps = 33/292 (11%)
Query: 106 QKYQRLLHEVQELTTEVEKIKTTVKESATEEKLTPVLLAKQLAALKQQLVASHLEKLLGP 165
+K+Q E++ LT E + +K T+KE A E K QL ++ +A E
Sbjct: 1335 EKFQESQEEIKSLTKERDNLK-TIKE-ALEVK------HDQLKEHIRETLAKIQESQSKQ 1386
Query: 166 DAAINLTDPDGALAKRLLLQLEATKNSKGGSGGKTTGTPPDSSLVTYELH----SRPEQD 221
+ ++N+ + D K ++ ++E K P DS+L+ E+ S+ Q+
Sbjct: 1387 EQSLNMKEKDNETTK-IVSEMEQFK-------------PKDSALLRIEIEMLGLSKRLQE 1432
Query: 222 KFSQAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSAL--DLA 279
+ VA+ + L L+ ++ + D + A +ET E L+ L
Sbjct: 1433 SHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIV-AKHLETEEELKVAHCCLKEQEE 1491
Query: 280 VLDQVEARLQSVLGKVNEIAKHKASVEDADTQSKVHQLYETIQRWSPIASTLPELVQRLV 339
++++ L +++ I K ++ D Q+K+ ++YE ++++ + E+ +++
Sbjct: 1492 TINELRVNLSEKETEISTIQKQLEAIND-KLQNKIQEIYEKEEQFN--IKQISEVQEKVN 1548
Query: 340 TIKQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQVQTTMRENLATVE 391
+KQ E L +++ + N L+++ + Q+ +E + V+
Sbjct: 1549 ELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEI-QIMIKEKEEMKRVQ 1599
>gi|5032281 dystrophin Dp427c isoform [Homo sapiens]
Length = 3677
Score = 39.7 bits (91), Expect = 0.005
Identities = 38/181 (20%), Positives = 80/181 (44%), Gaps = 16/181 (8%)
Query: 225 QAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQV 284
Q A + +LE+R +LE + Q+ +N S + + +E +Q + D+V
Sbjct: 2505 QKATMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQ--------WDEV 2556
Query: 285 EARLQSVLGKVNEIAKHKASVEDA--DTQSKVHQLYETIQRWSPIASTLPELVQRLVTIK 342
+ LQ+ ++NE+ K +A + + + Q ++ W T+ + +++ K
Sbjct: 2557 QEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETK 2616
Query: 343 QLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMK 402
QL A Q T++D + L+D + T+ + EN + ++ SI +R+
Sbjct: 2617 QL---AKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITEN---INASWRSIHKRVS 2670
Query: 403 K 403
+
Sbjct: 2671 E 2671
Score = 32.3 bits (72), Expect = 0.79
Identities = 32/137 (23%), Positives = 60/137 (43%), Gaps = 12/137 (8%)
Query: 278 LAVLDQVEARLQSVLGKVNEI----AKHKASVEDADTQSKVHQLYETIQRWSPIASTLPE 333
L++LDQV + ++G + +I K KA+++D + + QL E I + +
Sbjct: 2478 LSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRP--QLEELITAAQNLKNKTSN 2535
Query: 334 LVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLL------TQVQTTMRENL 387
R + ++ Q+ ++ HL +Q + LKD+T L QV R L
Sbjct: 2536 QEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKL 2595
Query: 388 ATVEGNFASIDERMKKL 404
+ + ++D KK+
Sbjct: 2596 ESWKEGPYTVDAIQKKI 2612
>gi|5032307 dystrophin Dp140c isoform [Homo sapiens]
Length = 1105
Score = 39.7 bits (91), Expect = 0.005
Identities = 38/181 (20%), Positives = 80/181 (44%), Gaps = 16/181 (8%)
Query: 225 QAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQV 284
Q A + +LE+R +LE + Q+ +N S + + +E +Q + D+V
Sbjct: 53 QKATMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQ--------WDEV 104
Query: 285 EARLQSVLGKVNEIAKHKASVEDA--DTQSKVHQLYETIQRWSPIASTLPELVQRLVTIK 342
+ LQ+ ++NE+ K +A + + + Q ++ W T+ + +++ K
Sbjct: 105 QEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETK 164
Query: 343 QLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMK 402
QL A Q T++D + L+D + T+ + EN + ++ SI +R+
Sbjct: 165 QL---AKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITEN---INASWRSIHKRVS 218
Query: 403 K 403
+
Sbjct: 219 E 219
Score = 32.3 bits (72), Expect = 0.79
Identities = 32/137 (23%), Positives = 60/137 (43%), Gaps = 12/137 (8%)
Query: 278 LAVLDQVEARLQSVLGKVNEI----AKHKASVEDADTQSKVHQLYETIQRWSPIASTLPE 333
L++LDQV + ++G + +I K KA+++D + + QL E I + +
Sbjct: 26 LSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRP--QLEELITAAQNLKNKTSN 83
Query: 334 LVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLL------TQVQTTMRENL 387
R + ++ Q+ ++ HL +Q + LKD+T L QV R L
Sbjct: 84 QEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKL 143
Query: 388 ATVEGNFASIDERMKKL 404
+ + ++D KK+
Sbjct: 144 ESWKEGPYTVDAIQKKI 160
>gi|5032291 dystrophin Dp260-2 isoform [Homo sapiens]
Length = 2341
Score = 39.7 bits (91), Expect = 0.005
Identities = 38/181 (20%), Positives = 80/181 (44%), Gaps = 16/181 (8%)
Query: 225 QAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQV 284
Q A + +LE+R +LE + Q+ +N S + + +E +Q + D+V
Sbjct: 1169 QKATMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQ--------WDEV 1220
Query: 285 EARLQSVLGKVNEIAKHKASVEDA--DTQSKVHQLYETIQRWSPIASTLPELVQRLVTIK 342
+ LQ+ ++NE+ K +A + + + Q ++ W T+ + +++ K
Sbjct: 1221 QEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETK 1280
Query: 343 QLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMK 402
QL A Q T++D + L+D + T+ + EN + ++ SI +R+
Sbjct: 1281 QL---AKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITEN---INASWRSIHKRVS 1334
Query: 403 K 403
+
Sbjct: 1335 E 1335
Score = 32.3 bits (72), Expect = 0.79
Identities = 32/137 (23%), Positives = 60/137 (43%), Gaps = 12/137 (8%)
Query: 278 LAVLDQVEARLQSVLGKVNEI----AKHKASVEDADTQSKVHQLYETIQRWSPIASTLPE 333
L++LDQV + ++G + +I K KA+++D + + QL E I + +
Sbjct: 1142 LSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRP--QLEELITAAQNLKNKTSN 1199
Query: 334 LVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLL------TQVQTTMRENL 387
R + ++ Q+ ++ HL +Q + LKD+T L QV R L
Sbjct: 1200 QEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKL 1259
Query: 388 ATVEGNFASIDERMKKL 404
+ + ++D KK+
Sbjct: 1260 ESWKEGPYTVDAIQKKI 1276
>gi|150036268 dystrophin Dp260-1 isoform [Homo sapiens]
Length = 2344
Score = 39.7 bits (91), Expect = 0.005
Identities = 38/181 (20%), Positives = 80/181 (44%), Gaps = 16/181 (8%)
Query: 225 QAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQV 284
Q A + +LE+R +LE + Q+ +N S + + +E +Q + D+V
Sbjct: 1172 QKATMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQ--------WDEV 1223
Query: 285 EARLQSVLGKVNEIAKHKASVEDA--DTQSKVHQLYETIQRWSPIASTLPELVQRLVTIK 342
+ LQ+ ++NE+ K +A + + + Q ++ W T+ + +++ K
Sbjct: 1224 QEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETK 1283
Query: 343 QLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMK 402
QL A Q T++D + L+D + T+ + EN + ++ SI +R+
Sbjct: 1284 QL---AKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITEN---INASWRSIHKRVS 1337
Query: 403 K 403
+
Sbjct: 1338 E 1338
Score = 32.3 bits (72), Expect = 0.79
Identities = 32/137 (23%), Positives = 60/137 (43%), Gaps = 12/137 (8%)
Query: 278 LAVLDQVEARLQSVLGKVNEI----AKHKASVEDADTQSKVHQLYETIQRWSPIASTLPE 333
L++LDQV + ++G + +I K KA+++D + + QL E I + +
Sbjct: 1145 LSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRP--QLEELITAAQNLKNKTSN 1202
Query: 334 LVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLL------TQVQTTMRENL 387
R + ++ Q+ ++ HL +Q + LKD+T L QV R L
Sbjct: 1203 QEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKL 1262
Query: 388 ATVEGNFASIDERMKKL 404
+ + ++D KK+
Sbjct: 1263 ESWKEGPYTVDAIQKKI 1279
>gi|5032315 dystrophin Dp427p2 isoform [Homo sapiens]
Length = 3562
Score = 39.7 bits (91), Expect = 0.005
Identities = 38/181 (20%), Positives = 80/181 (44%), Gaps = 16/181 (8%)
Query: 225 QAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQV 284
Q A + +LE+R +LE + Q+ +N S + + +E +Q + D+V
Sbjct: 2390 QKATMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQ--------WDEV 2441
Query: 285 EARLQSVLGKVNEIAKHKASVEDA--DTQSKVHQLYETIQRWSPIASTLPELVQRLVTIK 342
+ LQ+ ++NE+ K +A + + + Q ++ W T+ + +++ K
Sbjct: 2442 QEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETK 2501
Query: 343 QLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMK 402
QL A Q T++D + L+D + T+ + EN + ++ SI +R+
Sbjct: 2502 QL---AKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITEN---INASWRSIHKRVS 2555
Query: 403 K 403
+
Sbjct: 2556 E 2556
Score = 32.3 bits (72), Expect = 0.79
Identities = 32/137 (23%), Positives = 60/137 (43%), Gaps = 12/137 (8%)
Query: 278 LAVLDQVEARLQSVLGKVNEI----AKHKASVEDADTQSKVHQLYETIQRWSPIASTLPE 333
L++LDQV + ++G + +I K KA+++D + + QL E I + +
Sbjct: 2363 LSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRP--QLEELITAAQNLKNKTSN 2420
Query: 334 LVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLL------TQVQTTMRENL 387
R + ++ Q+ ++ HL +Q + LKD+T L QV R L
Sbjct: 2421 QEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKL 2480
Query: 388 ATVEGNFASIDERMKKL 404
+ + ++D KK+
Sbjct: 2481 ESWKEGPYTVDAIQKKI 2497
>gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens]
Length = 3681
Score = 39.7 bits (91), Expect = 0.005
Identities = 38/181 (20%), Positives = 80/181 (44%), Gaps = 16/181 (8%)
Query: 225 QAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQV 284
Q A + +LE+R +LE + Q+ +N S + + +E +Q + D+V
Sbjct: 2509 QKATMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQ--------WDEV 2560
Query: 285 EARLQSVLGKVNEIAKHKASVEDA--DTQSKVHQLYETIQRWSPIASTLPELVQRLVTIK 342
+ LQ+ ++NE+ K +A + + + Q ++ W T+ + +++ K
Sbjct: 2561 QEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETK 2620
Query: 343 QLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMK 402
QL A Q T++D + L+D + T+ + EN + ++ SI +R+
Sbjct: 2621 QL---AKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITEN---INASWRSIHKRVS 2674
Query: 403 K 403
+
Sbjct: 2675 E 2675
Score = 32.3 bits (72), Expect = 0.79
Identities = 32/137 (23%), Positives = 60/137 (43%), Gaps = 12/137 (8%)
Query: 278 LAVLDQVEARLQSVLGKVNEI----AKHKASVEDADTQSKVHQLYETIQRWSPIASTLPE 333
L++LDQV + ++G + +I K KA+++D + + QL E I + +
Sbjct: 2482 LSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRP--QLEELITAAQNLKNKTSN 2539
Query: 334 LVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLL------TQVQTTMRENL 387
R + ++ Q+ ++ HL +Q + LKD+T L QV R L
Sbjct: 2540 QEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKL 2599
Query: 388 ATVEGNFASIDERMKKL 404
+ + ++D KK+
Sbjct: 2600 ESWKEGPYTVDAIQKKI 2616
>gi|5032313 dystrophin Dp140bc isoform [Homo sapiens]
Length = 1133
Score = 39.7 bits (91), Expect = 0.005
Identities = 38/181 (20%), Positives = 80/181 (44%), Gaps = 16/181 (8%)
Query: 225 QAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQV 284
Q A + +LE+R +LE + Q+ +N S + + +E +Q + D+V
Sbjct: 53 QKATMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQ--------WDEV 104
Query: 285 EARLQSVLGKVNEIAKHKASVEDA--DTQSKVHQLYETIQRWSPIASTLPELVQRLVTIK 342
+ LQ+ ++NE+ K +A + + + Q ++ W T+ + +++ K
Sbjct: 105 QEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETK 164
Query: 343 QLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMK 402
QL A Q T++D + L+D + T+ + EN + ++ SI +R+
Sbjct: 165 QL---AKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITEN---INASWRSIHKRVS 218
Query: 403 K 403
+
Sbjct: 219 E 219
Score = 32.3 bits (72), Expect = 0.79
Identities = 32/137 (23%), Positives = 60/137 (43%), Gaps = 12/137 (8%)
Query: 278 LAVLDQVEARLQSVLGKVNEI----AKHKASVEDADTQSKVHQLYETIQRWSPIASTLPE 333
L++LDQV + ++G + +I K KA+++D + + QL E I + +
Sbjct: 26 LSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRP--QLEELITAAQNLKNKTSN 83
Query: 334 LVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLL------TQVQTTMRENL 387
R + ++ Q+ ++ HL +Q + LKD+T L QV R L
Sbjct: 84 QEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKL 143
Query: 388 ATVEGNFASIDERMKKL 404
+ + ++D KK+
Sbjct: 144 ESWKEGPYTVDAIQKKI 160
>gi|5032311 dystrophin Dp140ab isoform [Homo sapiens]
Length = 1230
Score = 39.7 bits (91), Expect = 0.005
Identities = 38/181 (20%), Positives = 80/181 (44%), Gaps = 16/181 (8%)
Query: 225 QAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQV 284
Q A + +LE+R +LE + Q+ +N S + + +E +Q + D+V
Sbjct: 53 QKATMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQ--------WDEV 104
Query: 285 EARLQSVLGKVNEIAKHKASVEDA--DTQSKVHQLYETIQRWSPIASTLPELVQRLVTIK 342
+ LQ+ ++NE+ K +A + + + Q ++ W T+ + +++ K
Sbjct: 105 QEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETK 164
Query: 343 QLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMK 402
QL A Q T++D + L+D + T+ + EN + ++ SI +R+
Sbjct: 165 QL---AKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITEN---INASWRSIHKRVS 218
Query: 403 K 403
+
Sbjct: 219 E 219
Score = 32.3 bits (72), Expect = 0.79
Identities = 32/137 (23%), Positives = 60/137 (43%), Gaps = 12/137 (8%)
Query: 278 LAVLDQVEARLQSVLGKVNEI----AKHKASVEDADTQSKVHQLYETIQRWSPIASTLPE 333
L++LDQV + ++G + +I K KA+++D + + QL E I + +
Sbjct: 26 LSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRP--QLEELITAAQNLKNKTSN 83
Query: 334 LVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLL------TQVQTTMRENL 387
R + ++ Q+ ++ HL +Q + LKD+T L QV R L
Sbjct: 84 QEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKL 143
Query: 388 ATVEGNFASIDERMKKL 404
+ + ++D KK+
Sbjct: 144 ESWKEGPYTVDAIQKKI 160
>gi|5032309 dystrophin Dp140b isoform [Homo sapiens]
Length = 1243
Score = 39.7 bits (91), Expect = 0.005
Identities = 38/181 (20%), Positives = 80/181 (44%), Gaps = 16/181 (8%)
Query: 225 QAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQV 284
Q A + +LE+R +LE + Q+ +N S + + +E +Q + D+V
Sbjct: 53 QKATMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQ--------WDEV 104
Query: 285 EARLQSVLGKVNEIAKHKASVEDA--DTQSKVHQLYETIQRWSPIASTLPELVQRLVTIK 342
+ LQ+ ++NE+ K +A + + + Q ++ W T+ + +++ K
Sbjct: 105 QEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETK 164
Query: 343 QLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMK 402
QL A Q T++D + L+D + T+ + EN + ++ SI +R+
Sbjct: 165 QL---AKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITEN---INASWRSIHKRVS 218
Query: 403 K 403
+
Sbjct: 219 E 219
Score = 32.3 bits (72), Expect = 0.79
Identities = 32/137 (23%), Positives = 60/137 (43%), Gaps = 12/137 (8%)
Query: 278 LAVLDQVEARLQSVLGKVNEI----AKHKASVEDADTQSKVHQLYETIQRWSPIASTLPE 333
L++LDQV + ++G + +I K KA+++D + + QL E I + +
Sbjct: 26 LSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRP--QLEELITAAQNLKNKTSN 83
Query: 334 LVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLL------TQVQTTMRENL 387
R + ++ Q+ ++ HL +Q + LKD+T L QV R L
Sbjct: 84 QEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKL 143
Query: 388 ATVEGNFASIDERMKKL 404
+ + ++D KK+
Sbjct: 144 ESWKEGPYTVDAIQKKI 160
>gi|5032293 dystrophin Dp140 isoform [Homo sapiens]
Length = 1225
Score = 39.7 bits (91), Expect = 0.005
Identities = 38/181 (20%), Positives = 80/181 (44%), Gaps = 16/181 (8%)
Query: 225 QAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQV 284
Q A + +LE+R +LE + Q+ +N S + + +E +Q + D+V
Sbjct: 53 QKATMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQ--------WDEV 104
Query: 285 EARLQSVLGKVNEIAKHKASVEDA--DTQSKVHQLYETIQRWSPIASTLPELVQRLVTIK 342
+ LQ+ ++NE+ K +A + + + Q ++ W T+ + +++ K
Sbjct: 105 QEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETK 164
Query: 343 QLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMK 402
QL A Q T++D + L+D + T+ + EN + ++ SI +R+
Sbjct: 165 QL---AKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITEN---INASWRSIHKRVS 218
Query: 403 K 403
+
Sbjct: 219 E 219
Score = 32.3 bits (72), Expect = 0.79
Identities = 32/137 (23%), Positives = 60/137 (43%), Gaps = 12/137 (8%)
Query: 278 LAVLDQVEARLQSVLGKVNEI----AKHKASVEDADTQSKVHQLYETIQRWSPIASTLPE 333
L++LDQV + ++G + +I K KA+++D + + QL E I + +
Sbjct: 26 LSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRP--QLEELITAAQNLKNKTSN 83
Query: 334 LVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLL------TQVQTTMRENL 387
R + ++ Q+ ++ HL +Q + LKD+T L QV R L
Sbjct: 84 QEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKL 143
Query: 388 ATVEGNFASIDERMKKL 404
+ + ++D KK+
Sbjct: 144 ESWKEGPYTVDAIQKKI 160
>gi|5032285 dystrophin Dp427l isoform [Homo sapiens]
Length = 3562
Score = 39.7 bits (91), Expect = 0.005
Identities = 38/181 (20%), Positives = 80/181 (44%), Gaps = 16/181 (8%)
Query: 225 QAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQV 284
Q A + +LE+R +LE + Q+ +N S + + +E +Q + D+V
Sbjct: 2390 QKATMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQ--------WDEV 2441
Query: 285 EARLQSVLGKVNEIAKHKASVEDA--DTQSKVHQLYETIQRWSPIASTLPELVQRLVTIK 342
+ LQ+ ++NE+ K +A + + + Q ++ W T+ + +++ K
Sbjct: 2442 QEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETK 2501
Query: 343 QLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMK 402
QL A Q T++D + L+D + T+ + EN + ++ SI +R+
Sbjct: 2502 QL---AKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITEN---INASWRSIHKRVS 2555
Query: 403 K 403
+
Sbjct: 2556 E 2556
Score = 32.3 bits (72), Expect = 0.79
Identities = 32/137 (23%), Positives = 60/137 (43%), Gaps = 12/137 (8%)
Query: 278 LAVLDQVEARLQSVLGKVNEI----AKHKASVEDADTQSKVHQLYETIQRWSPIASTLPE 333
L++LDQV + ++G + +I K KA+++D + + QL E I + +
Sbjct: 2363 LSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRP--QLEELITAAQNLKNKTSN 2420
Query: 334 LVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLL------TQVQTTMRENL 387
R + ++ Q+ ++ HL +Q + LKD+T L QV R L
Sbjct: 2421 QEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKL 2480
Query: 388 ATVEGNFASIDERMKKL 404
+ + ++D KK+
Sbjct: 2481 ESWKEGPYTVDAIQKKI 2497
>gi|5032283 dystrophin Dp427m isoform [Homo sapiens]
Length = 3685
Score = 39.7 bits (91), Expect = 0.005
Identities = 38/181 (20%), Positives = 80/181 (44%), Gaps = 16/181 (8%)
Query: 225 QAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQV 284
Q A + +LE+R +LE + Q+ +N S + + +E +Q + D+V
Sbjct: 2513 QKATMQDLEQRRPQLEELITAAQNLKNKTSNQEARTIITDRIERIQNQ--------WDEV 2564
Query: 285 EARLQSVLGKVNEIAKHKASVEDA--DTQSKVHQLYETIQRWSPIASTLPELVQRLVTIK 342
+ LQ+ ++NE+ K +A + + + Q ++ W T+ + +++ K
Sbjct: 2565 QEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKLESWKEGPYTVDAIQKKITETK 2624
Query: 343 QLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQVQTTMRENLATVEGNFASIDERMK 402
QL A Q T++D + L+D + T+ + EN + ++ SI +R+
Sbjct: 2625 QL---AKDLRQWQTNVDVANDLALKLLRDYSADDTRKVHMITEN---INASWRSIHKRVS 2678
Query: 403 K 403
+
Sbjct: 2679 E 2679
Score = 32.3 bits (72), Expect = 0.79
Identities = 32/137 (23%), Positives = 60/137 (43%), Gaps = 12/137 (8%)
Query: 278 LAVLDQVEARLQSVLGKVNEI----AKHKASVEDADTQSKVHQLYETIQRWSPIASTLPE 333
L++LDQV + ++G + +I K KA+++D + + QL E I + +
Sbjct: 2486 LSLLDQVIKSQRVMVGDLEDINEMIIKQKATMQDLEQRRP--QLEELITAAQNLKNKTSN 2543
Query: 334 LVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLL------TQVQTTMRENL 387
R + ++ Q+ ++ HL +Q + LKD+T L QV R L
Sbjct: 2544 QEARTIITDRIERIQNQWDEVQEHLQNRRQQLNEMLKDSTQWLEAKEEAEQVLGQARAKL 2603
Query: 388 ATVEGNFASIDERMKKL 404
+ + ++D KK+
Sbjct: 2604 ESWKEGPYTVDAIQKKI 2620
>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
Length = 1476
Score = 39.3 bits (90), Expect = 0.006
Identities = 89/373 (23%), Positives = 144/373 (38%), Gaps = 78/373 (20%)
Query: 96 EGLGVKETPQQKYQRLLHEVQELTTEVEKIKTTVKESATEEKLTPVLLAKQLAALKQ--- 152
E L KE+ Q+YQ L Q L E++ T+ +E+ E K + L ++L L+Q
Sbjct: 904 EFLREKESQHQRYQGL---EQRLEAELQAAATSKEEALMELKTRALQLEEELFQLRQGPA 960
Query: 153 ----------QLVASHLEKLLGPDAAINLTDPDGALAKRLLLQLEATKNSKGGSGGKTTG 202
QLV + +L+ + + + + A + L LE S G +
Sbjct: 961 GLGPKKRAEPQLVETQNVRLIEVERSNAMLVAEKAALQGQLQHLEGQLGSLQGRAQELLL 1020
Query: 203 TPPDSSLVTYELHSRPEQDKFSQAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACL 262
S E SR + +K + EL ++L LE VR + +Q + G Q A L
Sbjct: 1021 ----QSQRAQEHSSRLQAEKSVLEIQGQELHRKLEVLEEEVRAARQSQEE-TRGQQQALL 1075
Query: 263 METVEL--------------------LQAKVSALDLAVLD------QVEARLQSVLGK-V 295
+ L L+A + AL+LA + Q++A+ SV + V
Sbjct: 1076 RDHKALAQLQRRQEAELEGLLVRHRDLKANMRALELAHRELQGRHEQLQAQRASVEAQEV 1135
Query: 296 NEIAKHKASVEDADTQSKVHQLYETIQRWSPIASTL---------------PELVQRLVT 340
+A+ + ++D Q + + +Q A L EL RL
Sbjct: 1136 ALLAERERLMQDGHRQRGLEEELRRLQSEHDRAQMLLAELSRERGELQGERGELRGRLAR 1195
Query: 341 IK----QLHEQAMQFGQLLTHLD------TTQQMIANSLK-----DNTTLLTQVQTTMRE 385
++ QL Q+ Q + LD TTQ + L+ +N LL +VQ RE
Sbjct: 1196 LELERAQLEMQSQQLRESNQQLDLSACRLTTQCELLTQLRSAQEEENRQLLAEVQALSRE 1255
Query: 386 NLATVEGNFASID 398
N +E + S D
Sbjct: 1256 NRELLERSLESRD 1268
>gi|81295809 pericentrin [Homo sapiens]
Length = 3336
Score = 38.9 bits (89), Expect = 0.008
Identities = 71/319 (22%), Positives = 129/319 (40%), Gaps = 39/319 (12%)
Query: 105 QQKYQRLLHEVQELTTEVEKIKTTVKESATEEKLTPVLLA-KQLAALKQQLVASHLE--- 160
+QK + + E Q T+ + +K ++ A EEKLT +LL ++ A ++Q + + E
Sbjct: 735 KQKTELMKQEFQRKETDWKVMKEELQREA-EEKLTLMLLELREKAESEKQTIINKFELRE 793
Query: 161 ---KLLGPDAAINLTDPDGALAKRL--LLQLEATKNSKGG----SGGKTTGTPPDSSLVT 211
+ L A + D + +L ++ L QLE S G+ T D L
Sbjct: 794 AEMRQLQDQQAAQILDLERSLTEQQGRLQQLEQDLTSDDALHCSQCGREPPTAQDGELAA 853
Query: 212 YELHSRPEQDKFSQAAKVAELEKRLTELETAVRCD--QDAQNPLSAGLQGACLMETVELL 269
+ ++ E K +TE +A + Q+AQ + LQ LL
Sbjct: 854 LHVKEDCALQLMLARSRFLEERKEITEKFSAEQDAFLQEAQEQHARELQ---------LL 904
Query: 270 QAKVSALDLAVLDQVEARLQSVLGKVNEIAKHK------ASVEDADTQSKVHQLYETIQR 323
Q + L+V ++EAR Q+ LG++ + K A V + T+ +
Sbjct: 905 QERHQQQLLSVTAELEARHQAALGELTASLESKQGALLAARVAELQTKHAADLGALETRH 964
Query: 324 WSPIASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQVQTTM 383
S + S + TI++ H QA++ L D +Q+ T L +++
Sbjct: 965 LSSLDSLESCYLSEFQTIREEHRQALE----LLRADFEEQLWKKDSLHQTILTQELEKLK 1020
Query: 384 RENLATVEGNFASIDERMK 402
R++ EG S+ + ++
Sbjct: 1021 RKH----EGELQSVRDHLR 1035
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 38.9 bits (89), Expect = 0.008
Identities = 71/327 (21%), Positives = 123/327 (37%), Gaps = 27/327 (8%)
Query: 100 VKETPQQKYQRLLHEVQELTTEVEKIKTTVKESAT--EEKLTPVLLAKQ----LAALKQQ 153
+ +TPQ + +RL ++ + + ++++ + E+ EK + + +Q LA L ++
Sbjct: 208 ILQTPQFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALLNEK 267
Query: 154 LVASHLEKLLGPDAAINLTDPDGALAKRL---LLQLEATKNSKGGSGGKTTGTPPDSSLV 210
AS LE P L D + +L RL L Q + K K K ++ +
Sbjct: 268 QAASPLE----PKELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDL 323
Query: 211 TYELHSRPEQDKFSQAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGA-CLMETVELL 269
+++L + Q A E+ + + + LSA LQ CL E E+L
Sbjct: 324 SFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEIL 383
Query: 270 QAKVSALD---LAVLDQVEARLQSVLGKVNEIAKHK---ASVEDADTQSKVHQLYETIQR 323
Q K+S L+ + D VLG V ++ K A++ +TQ + +R
Sbjct: 384 QGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETER 443
Query: 324 WSPIASTL-------PELVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLL 376
A L E Q I L Q L+ Q L L
Sbjct: 444 GQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASL 503
Query: 377 TQVQTTMRENLATVEGNFASIDERMKK 403
T TT+ + + A + ++ K+
Sbjct: 504 TSELTTLNATIQQQDQELAGLKQQAKE 530
Score = 38.5 bits (88), Expect = 0.011
Identities = 43/198 (21%), Positives = 91/198 (45%), Gaps = 15/198 (7%)
Query: 105 QQKYQRLLHEVQELTTEVEKIKTTVKESATEEKLTPVLLAKQLAALKQQLVASHLEKLLG 164
+Q Q L H+V++L++ +++ + +KE A +++ T A+QLA ++ AS E+
Sbjct: 543 EQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRER--- 599
Query: 165 PDAAIN----LTDPDGALAKRLLLQLEATKNSKGGSGGKTTGTPPDSSLVTYELH----- 215
DAA+ L A + L QL+ ++ + T + + ++ ++
Sbjct: 600 -DAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQAC 658
Query: 216 -SRPEQDKFSQAAKVAELEKRL-TELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKV 273
Q++ A+VAELE +L +E + A ++ AQ Q L E++++ + +
Sbjct: 659 VETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSL 718
Query: 274 SALDLAVLDQVEARLQSV 291
D +E + + +
Sbjct: 719 EEEKRRAADALEEQQRCI 736
Score = 33.1 bits (74), Expect = 0.46
Identities = 54/245 (22%), Positives = 101/245 (41%), Gaps = 15/245 (6%)
Query: 40 LEELTSTSVEHIIVNPNAAYDKFKDKRVGTKGLDFSDRIGKTKRTGYESG-EYE-MLGEG 97
L E + + + V + A +K+ + + D R+ + +R + E E M +
Sbjct: 1454 LGERANLGRQFLEVELDQAREKYVQELAAVRA-DAETRLAEVQREAQSTARELEVMTAKY 1512
Query: 98 LGVKETPQQKYQRLLHEVQELTTEVEKIKTTVKESATE-EKLTPVLLAKQLAALKQQLVA 156
G K ++ QR E Q+LT +VE+++ +E + E+L+ L A+ QQ
Sbjct: 1513 EGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQ--- 1569
Query: 157 SHLEKLLGPDAAINLTDPDGALAKRLLLQLEATKNSKGGSGGKTTGTPPDSSLVTYELHS 216
+KL A + + + L +L+A + K + + + Y+
Sbjct: 1570 ---QKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQK-EQAAEHYKLQMEKAKTHYDAKK 1625
Query: 217 RPEQDKFSQAAKVAELEKRLTELET-AVRCDQDAQNPLSAGLQGACLMETVELLQAKVSA 275
+ Q+ Q + +L+K EL A R + Q AGL+ +T L A+V +
Sbjct: 1626 QQNQELQEQLRSLEQLQKENKELRAEAERLGHELQ---QAGLKTKEAEQTCRHLTAQVRS 1682
Query: 276 LDLAV 280
L+ V
Sbjct: 1683 LEAQV 1687
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 37.0 bits (84), Expect = 0.032
Identities = 65/306 (21%), Positives = 113/306 (36%), Gaps = 73/306 (23%)
Query: 102 ETPQQKYQRLLHEVQELTTEVEKIKTTVKESATEEKLTPVLLAKQLAALKQQLVASHLEK 161
E Q+K+ +LL E + ++ + + + + A E++ + LA+ L +Q + LE+
Sbjct: 1440 EKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQ--KAELER 1497
Query: 162 LLGPDAAINLTDPDGALAKRLLLQLEATKNSKGGSGGKTTGTPPDSSLVTYELHSRPEQD 221
L K+ ++E +SK G +EL E+
Sbjct: 1498 L----------------NKQFRTEMEDLMSSKDDVGKSV-----------HEL----EKS 1526
Query: 222 KFSQAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVL 281
K + +V E++ +L ELE ++ +DA+ L LQ A+
Sbjct: 1527 KRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQ--------------------AMK 1566
Query: 282 DQVEARLQSVLGKVNEIAKHKASVEDADTQSKVHQLYETIQRWSPIASTLPELVQRLVTI 341
Q E LQ D ++ K QL ++ A E QR + +
Sbjct: 1567 AQFERDLQG---------------RDEQSEEKKKQLVRQVREME--AELEDERKQRSMAV 1609
Query: 342 KQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQVQTTMRE---NLATVEGNFASID 398
+ M L H+D+ + ++K L Q++ MRE A+ E A
Sbjct: 1610 AARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAK 1669
Query: 399 ERMKKL 404
E KKL
Sbjct: 1670 ENEKKL 1675
Score = 31.6 bits (70), Expect = 1.3
Identities = 35/145 (24%), Positives = 69/145 (47%), Gaps = 17/145 (11%)
Query: 228 KVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQVEAR 287
K+ ELE +++EL+ + ++ ++N A Q L E +E L+ ++ LD A+
Sbjct: 1105 KIRELESQISELQEDLESERASRN--KAEKQKRDLGEELEALKTELE----DTLDSTAAQ 1158
Query: 288 LQSVLGKVNEIAKHKASVEDADTQSKVH--QLYETIQRWSPIASTLPELVQRLVTIKQLH 345
+ + E+ K ++E+ ++K H Q+ E Q+ S L E +++ +K
Sbjct: 1159 QELRSKREQEVNILKKTLEE---EAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANL 1215
Query: 346 EQAMQFGQLLTHLDTTQQMIANSLK 370
E+A Q L+ + +AN +K
Sbjct: 1216 EKAKQ------TLENERGELANEVK 1234
>gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens]
Length = 3661
Score = 37.0 bits (84), Expect = 0.032
Identities = 38/143 (26%), Positives = 69/143 (48%), Gaps = 13/143 (9%)
Query: 270 QAKVSALDLAVLDQVEARLQSVLGKVNEIAKHKASV--EDADTQSKVHQLYETIQRWSPI 327
++KVS DL VE +Q +GK +++ ++A+V DT K H L ++
Sbjct: 3129 ESKVSVDDLCK-KAVEHNIQ--IGKFSQLVMNRATVLASSYDTAWKKHDLVRRLETSISS 3185
Query: 328 ASTLPELVQRLVTIKQLHEQAMQFG--QLLTHLDTTQQMIANSLKDNTTLLTQVQT---T 382
T + VQ + + Q + + Q ++ + I S+K L+Q++T T
Sbjct: 3186 CKTSLQRVQLHIAMFQWQHEDLLINRPQAMSVTPPPRSAILTSMKKKLHTLSQIETSIAT 3245
Query: 383 MRENLATVEGNFASIDERMKKLG 405
++E LA +E +SI++R+K G
Sbjct: 3246 VQEKLAALE---SSIEQRLKWAG 3265
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 37.0 bits (84), Expect = 0.032
Identities = 59/299 (19%), Positives = 123/299 (41%), Gaps = 44/299 (14%)
Query: 92 EMLGEGLGVKETPQQKYQRLLHEVQELTTEVEKIKTTVKESATEEKLTPVLLAKQLAALK 151
E++ E + ++ +Q LH L E+E+I T + S +K L
Sbjct: 407 ELMEENMTLEMAQKQSMDESLH----LGWELEQISRTSELSEAPQK--------SLGHEV 454
Query: 152 QQLVASHLEKLLGPDAAINLTDPDGALAKRLLLQLEATKNSKGGSGGKTTGTPPDSSLVT 211
+L +S L KL + ++ T + +L T +S G+ K
Sbjct: 455 NELTSSRLLKLEMENQSLTKT----------VEELRTTVDSVEGNASKI----------- 493
Query: 212 YELHSRPEQDKFSQAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQA 271
L E + S+ KV LE + + + +++ Q+ L + A L +T+E L+
Sbjct: 494 --LKMEKENQRLSK--KVEILENEIVQEKQSLQNCQNLSKDLMK--EKAQLEKTIETLRE 547
Query: 272 KVSALDLAVLDQVEARLQSVLGKVNEIAK--HKASVEDADTQSKV--HQLYETIQRWSPI 327
S + +L+Q L + + + ++ +A V+D + ++K+ + ET + S I
Sbjct: 548 N-SERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKI 606
Query: 328 ASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQVQTTMREN 386
++ + L K+ E+A + L HL+ +++ + + +++ +EN
Sbjct: 607 EFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQEN 665
Score = 31.6 bits (70), Expect = 1.3
Identities = 59/313 (18%), Positives = 129/313 (41%), Gaps = 30/313 (9%)
Query: 87 ESGEYEMLGEGLGVKETPQQKYQRLLHEVQELTTEVEKIKTTVKESATEEKLTPVLLAKQ 146
++ EYE L G ++ + + ++++ ++ K K +++ EK+ V K
Sbjct: 1170 QASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDL---EKMLKVEQEKM 1226
Query: 147 LAALKQ-QLVASHLEKLLGPDAAINLTDPDGALAKRLLLQLEATKNSKGGSGGKTTGTPP 205
L K + VA+ +KL G + +N T +LL + E + +
Sbjct: 1227 LLENKNHETVAAEYKKLCGENDRLNHT------YSQLLKETEVLQTDHKNLKSLLNNSKL 1280
Query: 206 DSSLVTYELHSRPEQDKFSQAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMET 265
+ + + E EQ + Q + EL + ++ + + +N +++
Sbjct: 1281 EQTRLEAEFSKLKEQ--YQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQN 1338
Query: 266 VELLQAKVSALDLAVLDQVEARLQSVLGKVNEIAKHKASVEDADT-QSKVHQLYETIQRW 324
LL+ + + DL ++Q + + K+NE+ + K +E+ Q K + +R
Sbjct: 1339 RTLLEQNMESKDLFHVEQ-----RQYIDKLNELRRQKEKLEEKIMDQYKFYDPSPPRRRG 1393
Query: 325 SPIASTLPELV----------QRLVTIKQLHEQAMQFGQLLTHLDT--TQQMIANSLKDN 372
+ I + +L+ Q+ +T+ + + L H D+ + + +NSL+D
Sbjct: 1394 NWITLKMRKLIKSKKDINRERQKSLTLTPTRSDSSEGFLQLPHQDSQDSSSVGSNSLEDG 1453
Query: 373 TTLLTQVQTTMRE 385
TL T+ +TM +
Sbjct: 1454 QTLGTKKSSTMND 1466
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 37.0 bits (84), Expect = 0.032
Identities = 59/299 (19%), Positives = 123/299 (41%), Gaps = 44/299 (14%)
Query: 92 EMLGEGLGVKETPQQKYQRLLHEVQELTTEVEKIKTTVKESATEEKLTPVLLAKQLAALK 151
E++ E + ++ +Q LH L E+E+I T + S +K L
Sbjct: 407 ELMEENMTLEMAQKQSMDESLH----LGWELEQISRTSELSEAPQK--------SLGHEV 454
Query: 152 QQLVASHLEKLLGPDAAINLTDPDGALAKRLLLQLEATKNSKGGSGGKTTGTPPDSSLVT 211
+L +S L KL + ++ T + +L T +S G+ K
Sbjct: 455 NELTSSRLLKLEMENQSLTKT----------VEELRTTVDSVEGNASKI----------- 493
Query: 212 YELHSRPEQDKFSQAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQA 271
L E + S+ KV LE + + + +++ Q+ L + A L +T+E L+
Sbjct: 494 --LKMEKENQRLSK--KVEILENEIVQEKQSLQNCQNLSKDLMK--EKAQLEKTIETLRE 547
Query: 272 KVSALDLAVLDQVEARLQSVLGKVNEIAK--HKASVEDADTQSKV--HQLYETIQRWSPI 327
S + +L+Q L + + + ++ +A V+D + ++K+ + ET + S I
Sbjct: 548 N-SERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKI 606
Query: 328 ASTLPELVQRLVTIKQLHEQAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQVQTTMREN 386
++ + L K+ E+A + L HL+ +++ + + +++ +EN
Sbjct: 607 EFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQEN 665
>gi|46593000 GRIP1 associated protein 1 isoform 2 [Homo sapiens]
Length = 625
Score = 36.6 bits (83), Expect = 0.042
Identities = 75/330 (22%), Positives = 125/330 (37%), Gaps = 80/330 (24%)
Query: 87 ESGEYEMLGEGLGVKETPQQKYQ-------RLLHEVQELTTEVEKIKTTVKESATEEKLT 139
+ EYE L +G K+ + Q RLL ++QE+ E E++ ++E+ +
Sbjct: 320 QQAEYEDL---MGQKDDLNSQLQESLRANSRLLEQLQEIGQEKEQLTQELQEARKSAEKR 376
Query: 140 PVLLAKQLAALKQQLVASHLEKLLGPDAAINLTDPDGALAKRLLLQLEATKNSKGGSGGK 199
+L +LA Q + H E+L A+ L L R + E
Sbjct: 377 KAML-DELAMETLQEKSQHKEEL----GAVRLRHEKEVLGVRARYERELR---------- 421
Query: 200 TTGTPPDSSLVTYELHSRPEQDKFSQAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQG 259
ELH ++ + ++ E + R ELET
Sbjct: 422 -------------ELHEDKKRQEEELRGQIREEKARTRELET------------------ 450
Query: 260 ACLMETVELLQAKVSALDLAVLDQVEARLQSVLGKVNEIAKHKASVEDADTQSKVHQLYE 319
L +TVE LQA+V ++D E RL+ GK E+ + +E A + H
Sbjct: 451 --LQQTVEELQAQVHSMD-GAKGWFERRLKEAEGKEEELQDVRDQLEQAQEERDCH---- 503
Query: 320 TIQRWSPIASTLPELV--QRLVTIK----------QLHEQAMQFGQLLTHLDTTQQMIAN 367
++ S + + + V QR++ K QLH + + +L L Q ++ N
Sbjct: 504 -LKTISSLKQEVKDTVDGQRILEKKGSAALKDLKRQLHLERKRADKLQERL---QDILTN 559
Query: 368 SLKDNTTLLTQVQTTMRENLATVEGNFASI 397
S K + L V + M T G+ +SI
Sbjct: 560 S-KSRSGLEELVLSEMNSPSRTQTGDSSSI 588
>gi|19913410 major vault protein [Homo sapiens]
Length = 893
Score = 35.8 bits (81), Expect = 0.071
Identities = 41/146 (28%), Positives = 63/146 (43%), Gaps = 12/146 (8%)
Query: 177 ALAKRLLLQLEATKNSKGGSGGKTTGTPPDSSLVTYELHSRPEQDKFSQAAKVAELEKRL 236
AL + + L +E T NS+ + ++ + E R E+ K ++ + K L
Sbjct: 653 ALQRSVQLAIEITTNSQEAAAKH------EAQRLEQEARGRLERQKILDQSEAEKARKEL 706
Query: 237 TELET---AVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQVEARLQSVLG 293
ELE AV A+ + + A + +LQAK+ A LA+ + EA LQ V
Sbjct: 707 LELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAI--ETEAELQRV-Q 763
Query: 294 KVNEIAKHKASVEDADTQSKVHQLYE 319
KV E+ A + SK QL E
Sbjct: 764 KVRELELVYARAQLELEVSKAQQLAE 789
>gi|19913412 major vault protein [Homo sapiens]
Length = 893
Score = 35.8 bits (81), Expect = 0.071
Identities = 41/146 (28%), Positives = 63/146 (43%), Gaps = 12/146 (8%)
Query: 177 ALAKRLLLQLEATKNSKGGSGGKTTGTPPDSSLVTYELHSRPEQDKFSQAAKVAELEKRL 236
AL + + L +E T NS+ + ++ + E R E+ K ++ + K L
Sbjct: 653 ALQRSVQLAIEITTNSQEAAAKH------EAQRLEQEARGRLERQKILDQSEAEKARKEL 706
Query: 237 TELET---AVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQVEARLQSVLG 293
ELE AV A+ + + A + +LQAK+ A LA+ + EA LQ V
Sbjct: 707 LELEALSMAVESTGTAKAEAESRAEAARIEGEGSVLQAKLKAQALAI--ETEAELQRV-Q 763
Query: 294 KVNEIAKHKASVEDADTQSKVHQLYE 319
KV E+ A + SK QL E
Sbjct: 764 KVRELELVYARAQLELEVSKAQQLAE 789
>gi|10337581 type I hair keratin 3B [Homo sapiens]
Length = 404
Score = 35.4 bits (80), Expect = 0.093
Identities = 48/192 (25%), Positives = 78/192 (40%), Gaps = 16/192 (8%)
Query: 224 SQAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKV------SALD 277
S KV +LE+ ELE +R Q PL + +T+E LQ K+ +A
Sbjct: 69 SYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQS-YFKTIEELQQKILCSKSENARL 127
Query: 278 LAVLDQVEARLQSVLGKVNEIAKHKASVEDADTQSKVHQLYETIQRWSPIASTLPELVQR 337
+ +D + K + VE +D S L E S + + + L +
Sbjct: 128 VVQIDNAKLAADDFRTKYQTEQSLRQLVE-SDINSLRRILDELTLCRSDLEAQMESLKEE 186
Query: 338 LVTIKQLHEQAM-----QFG-QLLTHLDTTQQMIANSLKDNTTLLTQVQTTMRENLATVE 391
L+++KQ HEQ + Q G +L +D + N + + T Q + + N VE
Sbjct: 187 LLSLKQNHEQEVNTLRCQLGDRLNVEVDAAPAVDLNQVLNETR--NQYEALVETNRREVE 244
Query: 392 GNFASIDERMKK 403
FA+ E + K
Sbjct: 245 QWFATQTEELNK 256
>gi|223278353 C-type lectin domain family 4, member M isoform 3
[Homo sapiens]
Length = 296
Score = 35.4 bits (80), Expect = 0.093
Identities = 32/133 (24%), Positives = 64/133 (48%), Gaps = 16/133 (12%)
Query: 222 KFSQAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVL 281
+ S+ +K+ E+ + LT+L+ AV + P + LQ + + + L+A V L
Sbjct: 74 ELSEKSKLQEIYQELTQLKAAV-----GELPEKSKLQE--IYQELTRLKAAVGELP---- 122
Query: 282 DQVEARLQSVLGKVNEIAKHKASVEDADTQSKVHQLYETIQRWSPIASTLPELVQRLVTI 341
+++LQ + E+ + KA+V + +SK+ ++Y+ + R LPE +
Sbjct: 123 --EKSKLQEIY---QELTRLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIY 177
Query: 342 KQLHEQAMQFGQL 354
++L E G+L
Sbjct: 178 QELTELKAAVGEL 190
Score = 32.0 bits (71), Expect = 1.0
Identities = 29/133 (21%), Positives = 64/133 (48%), Gaps = 16/133 (12%)
Query: 225 QAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQV 284
+ +K+ E+ + LT L+ AV + P + LQ + + + L+A V L
Sbjct: 123 EKSKLQEIYQELTRLKAAV-----GELPEKSKLQE--IYQELTRLKAAVGELP------E 169
Query: 285 EARLQSVLGKVNEIAKHKASVEDADTQSKVHQLYETIQRWSPIASTLPELVQRLVTIKQL 344
+++LQ + ++ E+ KA+V + +SK+ ++Y+ + + LP+ ++ ++L
Sbjct: 170 KSKLQEIYQELTEL---KAAVGELPEKSKLQEIYQELTQLKAAVGELPDQSKQQQIYQEL 226
Query: 345 HEQAMQFGQLLTH 357
+ F +L H
Sbjct: 227 TDLKTAFERLCRH 239
>gi|42542390 C-type lectin domain family 4, member M isoform 1 [Homo
sapiens]
Length = 399
Score = 35.4 bits (80), Expect = 0.093
Identities = 32/133 (24%), Positives = 64/133 (48%), Gaps = 16/133 (12%)
Query: 222 KFSQAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVL 281
+ S+ +K+ E+ + LT+L+ AV + P + LQ + + + L+A V L
Sbjct: 102 ELSEKSKLQEIYQELTQLKAAV-----GELPEKSKLQE--IYQELTRLKAAVGELP---- 150
Query: 282 DQVEARLQSVLGKVNEIAKHKASVEDADTQSKVHQLYETIQRWSPIASTLPELVQRLVTI 341
+++LQ + E+ + KA+V + +SK+ ++Y+ + R LPE +
Sbjct: 151 --EKSKLQEIY---QELTRLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIY 205
Query: 342 KQLHEQAMQFGQL 354
++L E G+L
Sbjct: 206 QELTELKAAVGEL 218
Score = 32.0 bits (71), Expect = 1.0
Identities = 29/133 (21%), Positives = 64/133 (48%), Gaps = 16/133 (12%)
Query: 225 QAAKVAELEKRLTELETAVRCDQDAQNPLSAGLQGACLMETVELLQAKVSALDLAVLDQV 284
+ +K+ E+ + LT L+ AV + P + LQ + + + L+A V L
Sbjct: 151 EKSKLQEIYQELTRLKAAV-----GELPEKSKLQE--IYQELTRLKAAVGELP------E 197
Query: 285 EARLQSVLGKVNEIAKHKASVEDADTQSKVHQLYETIQRWSPIASTLPELVQRLVTIKQL 344
+++LQ + ++ E+ KA+V + +SK+ ++Y+ + + LP+ ++ ++L
Sbjct: 198 KSKLQEIYQELTEL---KAAVGELPEKSKLQEIYQELTQLKAAVGELPDQSKQQQIYQEL 254
Query: 345 HEQAMQFGQLLTH 357
+ F +L H
Sbjct: 255 TDLKTAFERLCRH 267
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.127 0.340
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,868,792
Number of Sequences: 37866
Number of extensions: 577849
Number of successful extensions: 2428
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 170
Number of HSP's that attempted gapping in prelim test: 2242
Number of HSP's gapped (non-prelim): 352
length of query: 406
length of database: 18,247,518
effective HSP length: 105
effective length of query: 301
effective length of database: 14,271,588
effective search space: 4295747988
effective search space used: 4295747988
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.