Guide to the Human Genome
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Search of human proteins with 53988387

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|53988387 tweety 2 isoform 2 [Homo sapiens]
         (213 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|53988385 tweety 2 isoform 1 [Homo sapiens]                         439   e-123
gi|53988387 tweety 2 isoform 2 [Homo sapiens]                         439   e-123
gi|51100978 tweety 3 [Homo sapiens]                                   167   5e-42
gi|10257437 tweety 1 isoform 1 [Homo sapiens]                         120   9e-28
gi|53831989 tweety 1 isoform 2 [Homo sapiens]                          99   3e-21
gi|91208420 bassoon protein [Homo sapiens]                             33   0.24 
gi|4827022 contactin 2 precursor [Homo sapiens]                        32   0.40 
gi|130492454 zinc finger RNA binding protein 2 isoform 1 [Homo s...    31   0.89 
gi|22749279 zinc finger protein 366 [Homo sapiens]                     30   2.0  
gi|41352705 kinesin family member 3C [Homo sapiens]                    30   2.0  
gi|209862845 nuclear factor of activated T-cells, cytoplasmic, c...    29   3.4  
gi|27886563 nuclear factor of activated T-cells, cytoplasmic, ca...    29   3.4  
gi|239756593 PREDICTED: UPF0607 protein ENSP00000381418-like [Ho...    29   3.4  
gi|170016091 odz, odd Oz/ten-m homolog 2 [Homo sapiens]                29   3.4  
gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens]        28   5.8  
gi|116235448 hypothetical protein LOC81610 [Homo sapiens]              28   7.6  
gi|169173146 PREDICTED: hypothetical protein [Homo sapiens]            27   9.9  
gi|58530876 melanoma antigen family C, 1 [Homo sapiens]                27   9.9  
gi|4502891 chloride channel, nucleotide-sensitive, 1A [Homo sapi...    27   9.9  
gi|154240686 FYVE, RhoGEF and PH domain containing 6 [Homo sapiens]    27   9.9  

>gi|53988385 tweety 2 isoform 1 [Homo sapiens]
          Length = 534

 Score =  439 bits (1128), Expect = e-123
 Identities = 213/213 (100%), Positives = 213/213 (100%)

Query: 1   MQIQVAGLLQFAVPLFSTAEEDLLAIQLLLNSSESSLHQLTAMVDCRGLHKDYLDALAGI 60
           MQIQVAGLLQFAVPLFSTAEEDLLAIQLLLNSSESSLHQLTAMVDCRGLHKDYLDALAGI
Sbjct: 322 MQIQVAGLLQFAVPLFSTAEEDLLAIQLLLNSSESSLHQLTAMVDCRGLHKDYLDALAGI 381

Query: 61  CYDGLQGLLYLGLFSFLAALAFSTMICAGPRAWKHFTTRNRDYDDIDDDDPFNPQAWRMA 120
           CYDGLQGLLYLGLFSFLAALAFSTMICAGPRAWKHFTTRNRDYDDIDDDDPFNPQAWRMA
Sbjct: 382 CYDGLQGLLYLGLFSFLAALAFSTMICAGPRAWKHFTTRNRDYDDIDDDDPFNPQAWRMA 441

Query: 121 AHSPPRGQLHSFCSYSSGLGSQTSLQPPAQTISNAPVSEYMNQAMLFGRNPRYENVPLIG 180
           AHSPPRGQLHSFCSYSSGLGSQTSLQPPAQTISNAPVSEYMNQAMLFGRNPRYENVPLIG
Sbjct: 442 AHSPPRGQLHSFCSYSSGLGSQTSLQPPAQTISNAPVSEYMNQAMLFGRNPRYENVPLIG 501

Query: 181 RASPPPTYSPSMRATYLSVADEHLRHYGNQFPA 213
           RASPPPTYSPSMRATYLSVADEHLRHYGNQFPA
Sbjct: 502 RASPPPTYSPSMRATYLSVADEHLRHYGNQFPA 534


>gi|53988387 tweety 2 isoform 2 [Homo sapiens]
          Length = 213

 Score =  439 bits (1128), Expect = e-123
 Identities = 213/213 (100%), Positives = 213/213 (100%)

Query: 1   MQIQVAGLLQFAVPLFSTAEEDLLAIQLLLNSSESSLHQLTAMVDCRGLHKDYLDALAGI 60
           MQIQVAGLLQFAVPLFSTAEEDLLAIQLLLNSSESSLHQLTAMVDCRGLHKDYLDALAGI
Sbjct: 1   MQIQVAGLLQFAVPLFSTAEEDLLAIQLLLNSSESSLHQLTAMVDCRGLHKDYLDALAGI 60

Query: 61  CYDGLQGLLYLGLFSFLAALAFSTMICAGPRAWKHFTTRNRDYDDIDDDDPFNPQAWRMA 120
           CYDGLQGLLYLGLFSFLAALAFSTMICAGPRAWKHFTTRNRDYDDIDDDDPFNPQAWRMA
Sbjct: 61  CYDGLQGLLYLGLFSFLAALAFSTMICAGPRAWKHFTTRNRDYDDIDDDDPFNPQAWRMA 120

Query: 121 AHSPPRGQLHSFCSYSSGLGSQTSLQPPAQTISNAPVSEYMNQAMLFGRNPRYENVPLIG 180
           AHSPPRGQLHSFCSYSSGLGSQTSLQPPAQTISNAPVSEYMNQAMLFGRNPRYENVPLIG
Sbjct: 121 AHSPPRGQLHSFCSYSSGLGSQTSLQPPAQTISNAPVSEYMNQAMLFGRNPRYENVPLIG 180

Query: 181 RASPPPTYSPSMRATYLSVADEHLRHYGNQFPA 213
           RASPPPTYSPSMRATYLSVADEHLRHYGNQFPA
Sbjct: 181 RASPPPTYSPSMRATYLSVADEHLRHYGNQFPA 213


>gi|51100978 tweety 3 [Homo sapiens]
          Length = 523

 Score =  167 bits (424), Expect = 5e-42
 Identities = 98/201 (48%), Positives = 128/201 (63%), Gaps = 9/201 (4%)

Query: 1   MQIQVAGLLQFAVPLFSTAEED-LLAIQLLLNSSESSLHQLTAMVDCRGLHKDYLDALAG 59
           MQ  VA LL+  VP    A +D LL +Q +LN +E +L  LTA+VDCR LH DY+ AL G
Sbjct: 321 MQDVVAELLR-TVPWEQPATKDPLLRVQEVLNGTEVNLQHLTALVDCRSLHLDYVQALTG 379

Query: 60  ICYDGLQGLLYLGLFSFLAALAFSTMICAGPRAWKHFTTRNRDYDDIDDDDPFNPQAWRM 119
            CYDG++GL+YL LFSF+ AL FS+++C+ P  W+    R  D D  ++  P      R 
Sbjct: 380 FCYDGVEGLIYLALFSFVTALMFSSIVCSVPHTWQQ--KRGPDEDGEEEAAP----GPRQ 433

Query: 120 AAHSPPRGQLHSFCSYSSGLGSQTSLQPPAQTISNAPVSEYMNQAMLFGRNPRYENVPLI 179
           A  S  R  + S  S  S  GS+TS+   A T+SNAPV+EYM+Q   F +NPR EN PLI
Sbjct: 434 AHDSLYRVHMPSLYSCGSSYGSETSIPAAAHTVSNAPVTEYMSQNANF-QNPRCENTPLI 492

Query: 180 GRASPPPTYSPSMRATYLSVA 200
           GR SPPP+Y+ SMRA YL+ +
Sbjct: 493 GRESPPPSYTSSMRAKYLATS 513


>gi|10257437 tweety 1 isoform 1 [Homo sapiens]
          Length = 450

 Score =  120 bits (301), Expect = 9e-28
 Identities = 60/112 (53%), Positives = 80/112 (71%), Gaps = 1/112 (0%)

Query: 4   QVAGLLQFAVPLFSTAEEDLLAIQLLLNSSESSLHQLTAMVDCRGLHKDYLDALAGICYD 63
           Q+ GL + AVP F +A++ LL+++  LN +E + HQL A++ CR LHKDY  AL G+C D
Sbjct: 328 QLLGLEREAVPQFPSAQKPLLSLEETLNVTEGNFHQLVALLHCRSLHKDYGAALRGLCED 387

Query: 64  GLQGLLYLGLFSFLAALAFSTMICAGPRAWKHFTTRNRDYDDIDDDDPFNPQ 115
            L+GLL+L LFS L+A A +T +C+ PRAW  F   + DYDD DDDDPFNPQ
Sbjct: 388 ALEGLLFLLLFSLLSAGALATALCSLPRAWALFPPSD-DYDDTDDDDPFNPQ 438


>gi|53831989 tweety 1 isoform 2 [Homo sapiens]
          Length = 460

 Score = 99.0 bits (245), Expect = 3e-21
 Identities = 49/97 (50%), Positives = 68/97 (70%)

Query: 4   QVAGLLQFAVPLFSTAEEDLLAIQLLLNSSESSLHQLTAMVDCRGLHKDYLDALAGICYD 63
           Q+ GL + AVP F +A++ LL+++  LN +E + HQL A++ CR LHKDY  AL G+C D
Sbjct: 328 QLLGLEREAVPQFPSAQKPLLSLEETLNVTEGNFHQLVALLHCRSLHKDYGAALRGLCED 387

Query: 64  GLQGLLYLGLFSFLAALAFSTMICAGPRAWKHFTTRN 100
            L+GLL+L LFS L+A A +T +C+ PRAW  F  RN
Sbjct: 388 ALEGLLFLLLFSLLSAGALATALCSLPRAWALFPPRN 424


>gi|91208420 bassoon protein [Homo sapiens]
          Length = 3926

 Score = 32.7 bits (73), Expect = 0.24
 Identities = 27/106 (25%), Positives = 41/106 (38%), Gaps = 12/106 (11%)

Query: 106  IDDDDPFNPQAWRMAAHSPPRGQLHSFCSYSSGLGSQTSLQPPAQTISN------APVSE 159
            + D  P +P A   A       +  S   +  GLGSQ S  PP   +        +P  E
Sbjct: 2850 LSDPKPLSPTAEESAK------ERFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPE 2903

Query: 160  YMNQAMLFGRNPRYENVPLIGRASPPPTYSPSMRATYLSVADEHLR 205
              +  +    +P+     L+ R    PT  P+ +A+ L   D  LR
Sbjct: 2904 EAHLPLAGQASPQLYAASLLQRGLTGPTTVPATKASLLRELDRDLR 2949


>gi|4827022 contactin 2 precursor [Homo sapiens]
          Length = 1040

 Score = 32.0 bits (71), Expect = 0.40
 Identities = 26/73 (35%), Positives = 33/73 (45%), Gaps = 11/73 (15%)

Query: 129 LHSFCSYSSGLGSQTSLQPPAQTISNAPVSEYMNQAMLFGRNPRYENVPLI--GRASPPP 186
           L S  ++SS LGSQT+           PV E    ++LF      E V L    RASPP 
Sbjct: 19  LVSSSAWSSALGSQTTF---------GPVFEDQPLSVLFPEESTEEQVLLACRARASPPA 69

Query: 187 TYSPSMRATYLSV 199
           TY   M  T + +
Sbjct: 70  TYRWKMNGTEMKL 82


>gi|130492454 zinc finger RNA binding protein 2 isoform 1 [Homo
           sapiens]
          Length = 939

 Score = 30.8 bits (68), Expect = 0.89
 Identities = 28/102 (27%), Positives = 38/102 (37%), Gaps = 12/102 (11%)

Query: 101 RDYDDIDDDDPFNPQAWRMAAHSPPRGQLHSFCSYSSGLGSQTSLQPPAQTISNAPVSEY 160
           R Y+D         Q+ RM A    +      C   S  GS +  QPP Q    AP+ E 
Sbjct: 100 RSYEDRPYFQSAALQSGRMTAADSGQPGTQEACGQPSPHGSHSHAQPPQQ----APIVES 155

Query: 161 MNQAMLFGRNPRY--------ENVPLIGRASPPPTYSPSMRA 194
              A        Y        E+   I  + PPP+Y+P+  A
Sbjct: 156 GQPASTLSSGYTYPTATGVQPESSASIVTSYPPPSYNPTCTA 197


>gi|22749279 zinc finger protein 366 [Homo sapiens]
          Length = 744

 Score = 29.6 bits (65), Expect = 2.0
 Identities = 21/73 (28%), Positives = 29/73 (39%), Gaps = 3/73 (4%)

Query: 122 HSPPRGQLHSFCSYSSGLGSQTSLQPPAQTISNAPVSEYMNQAMLFGRNPRY--ENVPLI 179
           + PP G L  F     G GS+     P +   N P  E +  A+    N  +   N+PL+
Sbjct: 57  YEPPPGDLDGFPGVFEGAGSRKRKSMPTKMPYNHPAEE-VTLALHSEENKNHGLPNLPLL 115

Query: 180 GRASPPPTYSPSM 192
               P P Y   M
Sbjct: 116 FPQPPRPKYDSQM 128


>gi|41352705 kinesin family member 3C [Homo sapiens]
          Length = 793

 Score = 29.6 bits (65), Expect = 2.0
 Identities = 16/48 (33%), Positives = 23/48 (47%), Gaps = 2/48 (4%)

Query: 141 SQTSLQPPAQTISNAPVSEYMNQAMLFGRNPRY--ENVPLIGRASPPP 186
           SQ   +P +      P+S+Y   AM  G +PRY  EN+  +     PP
Sbjct: 672 SQMKKRPTSAVGYKRPISQYARVAMAMGSHPRYRAENIMFLELDVSPP 719


>gi|209862845 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 4 isoform 1 [Homo sapiens]
          Length = 964

 Score = 28.9 bits (63), Expect = 3.4
 Identities = 18/70 (25%), Positives = 26/70 (37%), Gaps = 1/70 (1%)

Query: 125 PRGQLHSFCSYSSG-LGSQTSLQPPAQTISNAPVSEYMNQAMLFGRNPRYENVPLIGRAS 183
           P   L  F S S+   G+     PP     + P  +   +         Y   PL  +  
Sbjct: 757 PDSSLRGFPSASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYPQTG 816

Query: 184 PPPTYSPSMR 193
           PPP+Y P +R
Sbjct: 817 PPPSYRPGLR 826


>gi|27886563 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 4 isoform 2 [Homo sapiens]
          Length = 902

 Score = 28.9 bits (63), Expect = 3.4
 Identities = 18/70 (25%), Positives = 26/70 (37%), Gaps = 1/70 (1%)

Query: 125 PRGQLHSFCSYSSG-LGSQTSLQPPAQTISNAPVSEYMNQAMLFGRNPRYENVPLIGRAS 183
           P   L  F S S+   G+     PP     + P  +   +         Y   PL  +  
Sbjct: 694 PDSSLRGFPSASATPFGTDMDFSPPRPPYPSYPHEDPACETPYLSEGFGYGMPPLYPQTG 753

Query: 184 PPPTYSPSMR 193
           PPP+Y P +R
Sbjct: 754 PPPSYRPGLR 763


>gi|239756593 PREDICTED: UPF0607 protein ENSP00000381418-like [Homo
           sapiens]
          Length = 415

 Score = 28.9 bits (63), Expect = 3.4
 Identities = 18/45 (40%), Positives = 21/45 (46%), Gaps = 1/45 (2%)

Query: 107 DDDDPFNPQAWRMAAHSPPRGQLHSFCSYS-SGLGSQTSLQPPAQ 150
           +D  P +P A   +  SPPR   HS C    SG   Q  L PP Q
Sbjct: 296 EDMQPKDPAALGSSRSSPPRAAGHSSCKRKLSGPLLQLQLTPPLQ 340


>gi|170016091 odz, odd Oz/ten-m homolog 2 [Homo sapiens]
          Length = 2765

 Score = 28.9 bits (63), Expect = 3.4
 Identities = 21/82 (25%), Positives = 36/82 (43%), Gaps = 3/82 (3%)

Query: 105 DIDDDDPFNPQAWRMAAHSPPRGQLHSFCSYSSGLGSQTSLQPPAQTISNAPVSEYMNQA 164
           D + D+ F+P ++ + A S P+    +  S      SQ++L+PP     N  +S + + A
Sbjct: 211 DTNPDEEFSPNSYLLRACSGPQ---QASSSGPPNHHSQSTLRPPLPPPHNHTLSHHHSSA 267

Query: 165 MLFGRNPRYENVPLIGRASPPP 186
               RN        I   +P P
Sbjct: 268 NSLNRNSLTNRRSQIHAPAPAP 289


>gi|5902104 SRY (sex determining region Y)-box 10 [Homo sapiens]
          Length = 466

 Score = 28.1 bits (61), Expect = 5.8
 Identities = 27/125 (21%), Positives = 47/125 (37%), Gaps = 6/125 (4%)

Query: 95  HFTTRNRDYDDIDDDDPFNPQAWRMAA---HSPPRGQLHSFCSYSS---GLGSQTSLQPP 148
           H    N D  +I  +   N + + +A    + PP G      SYS+   GLGS  ++   
Sbjct: 270 HIDFGNVDIGEISHEVMSNMETFDVAELDQYLPPNGHPGHVSSYSAAGYGLGSALAVASG 329

Query: 149 AQTISNAPVSEYMNQAMLFGRNPRYENVPLIGRASPPPTYSPSMRATYLSVADEHLRHYG 208
                + P    +      G + + +          PP Y+     + ++     L HYG
Sbjct: 330 HSAWISKPPGVALPTVSPPGVDAKAQVKTETAGPQGPPHYTDQPSTSQIAYTSLSLPHYG 389

Query: 209 NQFPA 213
           + FP+
Sbjct: 390 SAFPS 394


>gi|116235448 hypothetical protein LOC81610 [Homo sapiens]
          Length = 615

 Score = 27.7 bits (60), Expect = 7.6
 Identities = 24/86 (27%), Positives = 33/86 (38%), Gaps = 11/86 (12%)

Query: 73  LFSFLAALAFSTMICAGPRAWKHFTTRNRDYDDIDDDD----------PFNPQAWRMAAH 122
           LFS    LA   ++  GP A+  F  R R    ++ D+          P    A   AA 
Sbjct: 57  LFSESRRLALEELVAGGPEAFAAFLRRERLARFLNPDEVHAILRAAERPGEEGAAAAAAA 116

Query: 123 SPPRGQLHSFCSYSSGLGSQTSLQPP 148
               G  H  CS  +    Q+ L+PP
Sbjct: 117 EDSFGSSHD-CSSGTYFPEQSDLEPP 141


>gi|169173146 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 464

 Score = 27.3 bits (59), Expect = 9.9
 Identities = 22/73 (30%), Positives = 30/73 (41%), Gaps = 10/73 (13%)

Query: 131 SFCSYSSGLGSQTSLQPPAQTISNAPVSEYMNQAMLFGRNPRY------ENVPLIGRASP 184
           S  ++S GLGS  S  P A+  + AP+   +N    F + PR       E+    G    
Sbjct: 272 SAATHSLGLGSNLSFGPGAKRPAQAPIQACLN----FPKKPRLGPFQIPESTIQGGELGA 327

Query: 185 PPTYSPSMRATYL 197
           P    P   AT L
Sbjct: 328 PENLQPPPAATEL 340


>gi|58530876 melanoma antigen family C, 1 [Homo sapiens]
          Length = 1142

 Score = 27.3 bits (59), Expect = 9.9
 Identities = 16/39 (41%), Positives = 22/39 (56%), Gaps = 4/39 (10%)

Query: 114 PQAWRMAAHSPPRGQ----LHSFCSYSSGLGSQTSLQPP 148
           PQ++  ++ SPP G     LHS  S   G+ SQ+ LQ P
Sbjct: 641 PQSFPESSQSPPEGPVQSPLHSPQSPPEGMHSQSPLQSP 679


>gi|4502891 chloride channel, nucleotide-sensitive, 1A [Homo
           sapiens]
          Length = 237

 Score = 27.3 bits (59), Expect = 9.9
 Identities = 13/43 (30%), Positives = 24/43 (55%), Gaps = 1/43 (2%)

Query: 102 DYDDIDDDDPFNPQAWRMAAHSPPRGQLHSFCSYSSGLGSQTS 144
           D +D D DD ++ + + + AH   +G + +F +Y  GL   T+
Sbjct: 138 DPEDEDSDD-YDGEEYDVEAHEQGQGDIPTFYTYEEGLSHLTA 179


>gi|154240686 FYVE, RhoGEF and PH domain containing 6 [Homo sapiens]
          Length = 1430

 Score = 27.3 bits (59), Expect = 9.9
 Identities = 20/76 (26%), Positives = 29/76 (38%), Gaps = 3/76 (3%)

Query: 126 RGQLHSFCSYSSGLGSQTSLQPPAQTISNAPVSEYMNQAMLFGRNPRYENVPLIGRASPP 185
           R  L   C+ + G+ S   +   A   S  PV +  +  + F  NP +     +   S P
Sbjct: 538 RNHLQHLCAQNRGVSSSFDMPKRA---SEKPVWKLPHPILPFSGNPEFLKSVTVSSNSEP 594

Query: 186 PTYSPSMRATYLSVAD 201
            T     RA  LS  D
Sbjct: 595 STALTKPRAKSLSAMD 610


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,006,711
Number of Sequences: 37866
Number of extensions: 412961
Number of successful extensions: 1139
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 1126
Number of HSP's gapped (non-prelim): 23
length of query: 213
length of database: 18,247,518
effective HSP length: 98
effective length of query: 115
effective length of database: 14,536,650
effective search space: 1671714750
effective search space used: 1671714750
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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