Guide to the Human Genome
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Search of human proteins with 53829374

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|53829374 plakophilin 4 isoform a [Homo sapiens]
         (1192 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|53829374 plakophilin 4 isoform a [Homo sapiens]                   2386   0.0  
gi|53829376 plakophilin 4 isoform b [Homo sapiens]                   2216   0.0  
gi|11034811 catenin (cadherin-associated protein), delta 2 (neur...  1080   0.0  
gi|4502247 armadillo repeat protein [Homo sapiens]                    472   e-133
gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens]               442   e-123
gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens]               442   e-123
gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens]               442   e-123
gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens]               442   e-123
gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens]              442   e-123
gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens]               442   e-123
gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens]               442   e-123
gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens]               442   e-123
gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens]                442   e-123
gi|146231962 catenin, delta 1 isoform 1AB [Homo sapiens]              442   e-123
gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens]              439   e-122
gi|146231970 catenin, delta 1 isoform 3ABC [Homo sapiens]             439   e-122
gi|146231940 catenin, delta 1 isoform 1ABC [Homo sapiens]             439   e-122
gi|148664186 plakophilin 2 isoform 2a [Homo sapiens]                  295   2e-79
gi|148664226 plakophilin 2 isoform 2b [Homo sapiens]                  273   5e-73
gi|53729344 plakophilin 1 isoform 1a [Homo sapiens]                   273   9e-73
gi|169218113 PREDICTED: similar to plakophilin 1, partial [Homo ...   273   9e-73
gi|53729346 plakophilin 1 isoform 1b [Homo sapiens]                   260   5e-69
gi|6005830 plakophilin 3 [Homo sapiens]                               259   1e-68
gi|161016767 mucin 21 [Homo sapiens]                                   49   2e-05
gi|189011568 adenomatous polyposis coli [Homo sapiens]                 47   8e-05
gi|189011566 adenomatous polyposis coli [Homo sapiens]                 47   8e-05
gi|53759122 adenomatous polyposis coli [Homo sapiens]                  47   8e-05
gi|67010025 Sp4 transcription factor [Homo sapiens]                    47   8e-05
gi|91206450 ankyrin and armadillo repeat containing [Homo sapiens]     47   1e-04
gi|189409124 armadillo repeat containing 3 [Homo sapiens]              46   2e-04

>gi|53829374 plakophilin 4 isoform a [Homo sapiens]
          Length = 1192

 Score = 2386 bits (6183), Expect = 0.0
 Identities = 1192/1192 (100%), Positives = 1192/1192 (100%)

Query: 1    MPAPEQASLVEEGQPQTRQEAASTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQ 60
            MPAPEQASLVEEGQPQTRQEAASTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQ
Sbjct: 1    MPAPEQASLVEEGQPQTRQEAASTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQ 60

Query: 61   IVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDAVQPNNYLIRTEP 120
            IVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDAVQPNNYLIRTEP
Sbjct: 61   IVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDAVQPNNYLIRTEP 120

Query: 121  EQGTLYSPEQTSLHESEGSLGNSRSSTQMNSYSDSGYQEAGSFHNSQNVSKADNRQQHSF 180
            EQGTLYSPEQTSLHESEGSLGNSRSSTQMNSYSDSGYQEAGSFHNSQNVSKADNRQQHSF
Sbjct: 121  EQGTLYSPEQTSLHESEGSLGNSRSSTQMNSYSDSGYQEAGSFHNSQNVSKADNRQQHSF 180

Query: 181  IGSTNNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVISTGVSPSRGSLRTS 240
            IGSTNNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVISTGVSPSRGSLRTS
Sbjct: 181  IGSTNNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVISTGVSPSRGSLRTS 240

Query: 241  LGSGFGSPSVTDPRPLNPSAYSSTTLPAARAASPYSQRPASPTAIRRIGSVTSRQTSNPN 300
            LGSGFGSPSVTDPRPLNPSAYSSTTLPAARAASPYSQRPASPTAIRRIGSVTSRQTSNPN
Sbjct: 241  LGSGFGSPSVTDPRPLNPSAYSSTTLPAARAASPYSQRPASPTAIRRIGSVTSRQTSNPN 300

Query: 301  GPTPQYQTTARVGSPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRTVHD 360
            GPTPQYQTTARVGSPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRTVHD
Sbjct: 301  GPTPQYQTTARVGSPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRTVHD 360

Query: 361  MEQFGQQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQDLRSAVSPDLHITPIYEGRTY 420
            MEQFGQQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQDLRSAVSPDLHITPIYEGRTY
Sbjct: 361  MEQFGQQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQDLRSAVSPDLHITPIYEGRTY 420

Query: 421  YSPVYRSPNHGTVELQGSQTALYRTGSVGIGNLQRTSSQRSTLTYQRNNYALNTTATYAE 480
            YSPVYRSPNHGTVELQGSQTALYRTGSVGIGNLQRTSSQRSTLTYQRNNYALNTTATYAE
Sbjct: 421  YSPVYRSPNHGTVELQGSQTALYRTGSVGIGNLQRTSSQRSTLTYQRNNYALNTTATYAE 480

Query: 481  PYRPIQYRVQECNYNRLQHAVPADDGTTRSPSIDSIQKDPREFAWRDPELPEVIHMLQHQ 540
            PYRPIQYRVQECNYNRLQHAVPADDGTTRSPSIDSIQKDPREFAWRDPELPEVIHMLQHQ
Sbjct: 481  PYRPIQYRVQECNYNRLQHAVPADDGTTRSPSIDSIQKDPREFAWRDPELPEVIHMLQHQ 540

Query: 541  FPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEVQKNACGALRNLVFG 600
            FPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEVQKNACGALRNLVFG
Sbjct: 541  FPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEVQKNACGALRNLVFG 600

Query: 601  KSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVKMTIIRDALSTL 660
            KSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVKMTIIRDALSTL
Sbjct: 601  KSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVKMTIIRDALSTL 660

Query: 661  TNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDS 720
            TNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDS
Sbjct: 661  TNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDS 720

Query: 721  LLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKD 780
            LLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKD
Sbjct: 721  LLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKD 780

Query: 781  SEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNP 840
            SEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNP
Sbjct: 781  SEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNP 840

Query: 841  ATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMA 900
            ATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMA
Sbjct: 841  ATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMA 900

Query: 901  LDVRNKELIGKYAMRDLVNRLPGGNGPSVLSDETMAAICCALHEVTSKNMENAKALADSG 960
            LDVRNKELIGKYAMRDLVNRLPGGNGPSVLSDETMAAICCALHEVTSKNMENAKALADSG
Sbjct: 901  LDVRNKELIGKYAMRDLVNRLPGGNGPSVLSDETMAAICCALHEVTSKNMENAKALADSG 960

Query: 961  GIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLER 1020
            GIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLER
Sbjct: 961  GIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLER 1020

Query: 1021 DRFKSHPSLSTTNQQMSPIIQSVGSTSSSPALLGIRDPRSEYDRTQPPMQYYNSQGDATH 1080
            DRFKSHPSLSTTNQQMSPIIQSVGSTSSSPALLGIRDPRSEYDRTQPPMQYYNSQGDATH
Sbjct: 1021 DRFKSHPSLSTTNQQMSPIIQSVGSTSSSPALLGIRDPRSEYDRTQPPMQYYNSQGDATH 1080

Query: 1081 KGLYPGSSKPSPIYISSYSSPAREQNRRLQHQQLYYSQDDSNRKNFDAYRLYLQSPHSYE 1140
            KGLYPGSSKPSPIYISSYSSPAREQNRRLQHQQLYYSQDDSNRKNFDAYRLYLQSPHSYE
Sbjct: 1081 KGLYPGSSKPSPIYISSYSSPAREQNRRLQHQQLYYSQDDSNRKNFDAYRLYLQSPHSYE 1140

Query: 1141 DPYFDDRVHFPASTDYSTQYGLKSTTNYVDFYSTKRPSYRAEQYPGSPDSWV 1192
            DPYFDDRVHFPASTDYSTQYGLKSTTNYVDFYSTKRPSYRAEQYPGSPDSWV
Sbjct: 1141 DPYFDDRVHFPASTDYSTQYGLKSTTNYVDFYSTKRPSYRAEQYPGSPDSWV 1192


>gi|53829376 plakophilin 4 isoform b [Homo sapiens]
          Length = 1149

 Score = 2216 bits (5742), Expect = 0.0
 Identities = 1124/1192 (94%), Positives = 1126/1192 (94%), Gaps = 43/1192 (3%)

Query: 1    MPAPEQASLVEEGQPQTRQEAASTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQ 60
            MPAPEQASLVEEGQPQTRQEAASTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQ
Sbjct: 1    MPAPEQASLVEEGQPQTRQEAASTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQ 60

Query: 61   IVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDAVQPNNYLIRTEP 120
            IVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDAVQPNNYLIRTEP
Sbjct: 61   IVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDAVQPNNYLIRTEP 120

Query: 121  EQGTLYSPEQTSLHESEGSLGNSRSSTQMNSYSDSGYQEAGSFHNSQNVSKADNRQQHSF 180
            EQGTLYSPEQTSLHESEGSLGNSRSSTQMNSYSDSGYQEAGSFHNSQNVSKADNRQQHSF
Sbjct: 121  EQGTLYSPEQTSLHESEGSLGNSRSSTQMNSYSDSGYQEAGSFHNSQNVSKADNRQQHSF 180

Query: 181  IGSTNNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVISTGVSPSRGSLRTS 240
            IGSTNNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVISTGVSPSRGSLRTS
Sbjct: 181  IGSTNNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVISTGVSPSRGSLRTS 240

Query: 241  LGSGFGSPSVTDPRPLNPSAYSSTTLPAARAASPYSQRPASPTAIRRIGSVTSRQTSNPN 300
            LGSGFGSPSVTDPRPLNPSAYSSTTLPAARAASPYSQRPASPTAIRRIGSVTSRQTSNPN
Sbjct: 241  LGSGFGSPSVTDPRPLNPSAYSSTTLPAARAASPYSQRPASPTAIRRIGSVTSRQTSNPN 300

Query: 301  GPTPQYQTTARVGSPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRTVHD 360
            GPTPQYQTTARVGSPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRTVHD
Sbjct: 301  GPTPQYQTTARVGSPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRTVHD 360

Query: 361  MEQFGQQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQDLRSAVSPDLHITPIYEGRTY 420
            MEQFGQQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQDLRSAVSPDLHITPIYEGRTY
Sbjct: 361  MEQFGQQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQDLRSAVSPDLHITPIYEGRTY 420

Query: 421  YSPVYRSPNHGTVELQGSQTALYRTGSVGIGNLQRTSSQRSTLTYQRNNYALNTTATYAE 480
            YSPVYRSPNHGTVELQGSQTALYRTGSVGIGNLQRTSSQRSTLTYQRNNYALNTTATYAE
Sbjct: 421  YSPVYRSPNHGTVELQGSQTALYRTGSVGIGNLQRTSSQRSTLTYQRNNYALNTTATYAE 480

Query: 481  PYRPIQYRVQECNYNRLQHAVPADDGTTRSPSIDSIQKDPREFAWRDPELPEVIHMLQHQ 540
            PYRPIQYRVQECNYNRLQHAVPADDGTTRSPSIDSIQKDPREFAWRDPELPEVIHMLQHQ
Sbjct: 481  PYRPIQYRVQECNYNRLQHAVPADDGTTRSPSIDSIQKDPREFAWRDPELPEVIHMLQHQ 540

Query: 541  FPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEVQKNACGALRNLVFG 600
            FPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEVQKNACGALRNLVFG
Sbjct: 541  FPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEVQKNACGALRNLVFG 600

Query: 601  KSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVKMTIIRDALSTL 660
            KSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVKMTIIRDALSTL
Sbjct: 601  KSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVKMTIIRDALSTL 660

Query: 661  TNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDS 720
            TNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDS
Sbjct: 661  TNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDS 720

Query: 721  LLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKD 780
            LLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKD
Sbjct: 721  LLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKD 780

Query: 781  SEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNP 840
            SEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNP
Sbjct: 781  SEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNP 840

Query: 841  ATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMA 900
            ATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMA
Sbjct: 841  ATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMA 900

Query: 901  LDVRNKELIGKYAMRDLVNRLPGGNGPSVLSDETMAAICCALHEVTSKNMENAKALADSG 960
            LDVRNKELIGKYAMRDLVNRLPGGNGPSVLSDETMAAICCALHEVTSKNMENAKALADSG
Sbjct: 901  LDVRNKELIGKYAMRDLVNRLPGGNGPSVLSDETMAAICCALHEVTSKNMENAKALADSG 960

Query: 961  GIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLER 1020
            GIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLER
Sbjct: 961  GIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLER 1020

Query: 1021 DRFKSHPSLSTTNQQMSPIIQSVGSTSSSPALLGIRDPRSEYDRTQPPMQYYNSQGDATH 1080
            DRFKSHPSLSTTNQQMSPIIQS  S  S   +     P  E +R     Q Y SQ D   
Sbjct: 1021 DRFKSHPSLSTTNQQMSPIIQSGSSKPSPIYISSYSSPAREQNRRLQHQQLYYSQDD--- 1077

Query: 1081 KGLYPGSSKPSPIYISSYSSPAREQNRRLQHQQLYYSQDDSNRKNFDAYRLYLQSPHSYE 1140
                                                    SNRKNFDAYRLYLQSPHSYE
Sbjct: 1078 ----------------------------------------SNRKNFDAYRLYLQSPHSYE 1097

Query: 1141 DPYFDDRVHFPASTDYSTQYGLKSTTNYVDFYSTKRPSYRAEQYPGSPDSWV 1192
            DPYFDDRVHFPASTDYSTQYGLKSTTNYVDFYSTKRPSYRAEQYPGSPDSWV
Sbjct: 1098 DPYFDDRVHFPASTDYSTQYGLKSTTNYVDFYSTKRPSYRAEQYPGSPDSWV 1149


>gi|11034811 catenin (cadherin-associated protein), delta 2 (neural
            plakophilin-related arm-repeat protein) [Homo sapiens]
          Length = 1225

 Score = 1080 bits (2792), Expect = 0.0
 Identities = 615/1241 (49%), Positives = 809/1241 (65%), Gaps = 79/1241 (6%)

Query: 1    MPAPEQASLVEEGQPQTRQEA-ASTGPGMEPETTATTILASVKEQELQFQRLTRELEVER 59
            MP P+Q S   E           S G G E ETT+  ILASVKEQELQF+RLTRELE ER
Sbjct: 15   MPVPDQPSSASEKTSSLSPGLNTSNGDGSETETTSA-ILASVKEQELQFERLTRELEAER 73

Query: 60   QIVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDAVQPNNYLIRTE 119
            QIVASQLERC+LG+E+ S++S SS E+ F W+S D       +  ++  ++  +  IR+ 
Sbjct: 74   QIVASQLERCKLGSETGSMSSMSSAEEQFQWQSQDGQKD--IEDELTTGLELVDSCIRSL 131

Query: 120  PEQGTLYSPEQTSLHESEGSLGNSRSSTQMNSYSDSGYQEAGSFHNSQNVSKADNRQQHS 179
             E G L  P+  S  E    L  S+S+ Q+NS  +  +Q   S+H++Q ++  +      
Sbjct: 132  QESGIL-DPQDYSTGERPSLL--SQSALQLNSKPEGSFQYPASYHSNQTLALGETTPSQL 188

Query: 180  FIGSTNNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVISTGVSPSRGSLRT 239
                T       +RA GQ+  Q    +RA       P+    P         P R     
Sbjct: 189  PARGTQ------ARATGQSFSQ-GTTSRAGHLAGPEPAPPPPP---------PPREPFAP 232

Query: 240  SLGSGFGSPSVTDPRPLNPSAYSSTTLPAA-RAASPYSQ-RPASPTAIRRIGSVTSRQT- 296
            SLGS F  P            YSS+TLPA  R  SP +  +  SPT ++R GS     T 
Sbjct: 233  SLGSAFHLPDAPPAAAAAALYYSSSTLPAPPRGGSPLAAPQGGSPTKLQRGGSAPEGATY 292

Query: 297  SNPNGPTPQYQTTARVGSPLTLTDAQTRVASPSQGQVGSSSPK--RSGMTAVPQH----- 349
            + P G +P+   +    S  T +     V+S     +  +SP   +S +++ P H     
Sbjct: 293  AAPRGSSPKQSPSRLAKSYSTSSPINIVVSSAGLSPIRVTSPPTVQSTISSSPIHQLSST 352

Query: 350  ------LGPSLQRTVHDMEQFGQQQYDIYERMVPPRPDSLT-GLRSSYASQHSQLGQDLR 402
                  L P+ +R VH  EQ+ +   ++Y      RP SL  G R+SY+SQH  LG +LR
Sbjct: 353  IGTYATLSPT-KRLVHASEQYSKHSQELYATATLQRPGSLAAGSRASYSSQHGHLGPELR 411

Query: 403  SAVSPDLHITPIYEGRTYYSPVYRSPNHGTVE-LQGSQTALYRTG----SVGIGN--LQR 455
            +  SP+ HI PIYE R Y  P  RS +    + L  + T  YRT     S G+ +  LQR
Sbjct: 412  ALQSPEHHIDPIYEDRVYQKPPMRSLSQSQGDPLPPAHTGTYRTSTAPSSPGVDSVPLQR 471

Query: 456  TSSQR-----STLTYQRNNYALNTTATYAEPYRPIQYRVQ-ECNYNRLQHAVPADDGTTR 509
            T SQ      +  T+QR +YA    + YA+PYR +QY    E  Y++   A+P +    R
Sbjct: 472  TGSQHGPQNAAAATFQRASYAAGPASNYADPYRQLQYCPSVESPYSKSGPALPPEGTLAR 531

Query: 510  SPSIDSIQKDPREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRL 569
            SPSIDSIQKDPREF WRDPELPEVI MLQHQFPSVQ+NAAAYLQHLCFGDNK+K E+ R 
Sbjct: 532  SPSIDSIQKDPREFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQ 591

Query: 570  GGIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDA 629
            GGI+ LVDLLDHR+ EV ++ACGALRNLV+GK+ D+NKIA+KN GGIPAL+RLLRK+ D 
Sbjct: 592  GGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDL 651

Query: 630  EVRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLV 689
            E+RELVTGVLWNLSSCDA+KM II+DAL+ LTN VI+PHSGW NS   DD KI+  +S V
Sbjct: 652  EIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQV 711

Query: 690  LRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNL 749
            LRN TGCLRN+SSAGEEAR++MR C+GL D+LLYVI + + +S+ DSKTVENCVC LRNL
Sbjct: 712  LRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRNL 771

Query: 750  SYRLELEVPQARLLGLNELDDLLGKESPSKDSEPS-CWGKKKKKKKRTPQEDQWDGVGPI 808
            SYRL  E  Q + +G +ELD LL  E+  KD+E S CWGKKKKKKK    +DQWDGVGP+
Sbjct: 772  SYRLAAETSQGQHMGTDELDGLLCGEANGKDAESSGCWGKKKKKKK---SQDQWDGVGPL 828

Query: 809  PGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAV 868
            P  ++ PKG++MLWHPS+VKPYLTLL+E SNP TLEG+AG+LQNL+AG+WK++ YIRAAV
Sbjct: 829  PDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKWSVYIRAAV 888

Query: 869  RKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPS 928
            RKEKGLPILVELLR+DNDRVV +VATALRNMALDVRNKELIGKYAMRDLV+RLPGGN  +
Sbjct: 889  RKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNSN 948

Query: 929  -----VLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKA 983
                  +SD+T+ A+CC LHEV +KNMENAKAL D+GGIEKLV I+K +GD+ S KVVKA
Sbjct: 949  NTASKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSPKVVKA 1008

Query: 984  AAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDRFKSHPSLSTTN---QQMSPII 1040
            A+QVLN++WQYRDLRS+YKKDGW+Q HF+   ST+ERDR + + S  T +    ++SP  
Sbjct: 1009 ASQVLNSMWQYRDLRSLYKKDGWSQYHFVASSSTIERDRQRPYSSSRTPSISPVRVSPNN 1068

Query: 1041 QSVGSTSSSPALLGIRDPRSEYDRTQPPMQYYNSQGDATHK--GLYPGSSKPSPIYISSY 1098
            +S  + +S   ++ +++ +++Y+ T     Y+ ++G+ T +   +   ++  S +Y +SY
Sbjct: 1069 RSASAPASPREMISLKERKTDYECTGSNATYHGAKGEHTSRKDAMTAQNTGISTLYRNSY 1128

Query: 1099 SSPAREQNRRLQHQQLYYS--QDDSNRKNFDAYRLYLQSPHSYEDPYFDDRVHF-PASTD 1155
             +PA +    ++H Q+       + +RK+++ Y+ +  S  +Y++ +F+D+VH  P +++
Sbjct: 1129 GAPAED----IKHNQVSAQPVPQEPSRKDYETYQPFQNSTRNYDESFFEDQVHHRPPASE 1184

Query: 1156 YSTQYGLKSTTNYVDFYSTKRP----SYRAEQYPGSPDSWV 1192
            Y+   GLKST NYVDFYS  RP    +Y    YP SPDSWV
Sbjct: 1185 YTMHLGLKSTGNYVDFYSAARPYSELNYETSHYPASPDSWV 1225


>gi|4502247 armadillo repeat protein [Homo sapiens]
          Length = 962

 Score =  472 bits (1215), Expect = e-133
 Identities = 271/606 (44%), Positives = 377/606 (62%), Gaps = 32/606 (5%)

Query: 509  RSPSIDSIQKDPREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCR 568
            RSPS+DS +K+PR   WRDPELPEV+ ML+H    V+ANAAAYLQHLCF +  VK  V +
Sbjct: 342  RSPSVDSARKEPR---WRDPELPEVLAMLRHPVDPVKANAAAYLQHLCFENEGVKRRVRQ 398

Query: 569  LGGIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSID 628
            L G+  LV LLDH   EV++ ACGALRNL +G+ TD NK A+++ GG+PAL+RLLR + D
Sbjct: 399  LRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDTD-NKAAIRDCGGVPALVRLLRAARD 457

Query: 629  AEVRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSL 688
             EVRELVTG LWNLSS + +KM II   L TLT+ VIVPHSGW     +D      + + 
Sbjct: 458  NEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLTHEVIVPHSGWEREPNEDSKPRDAEWTT 517

Query: 689  VLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRN 748
            V +NT+GCLRN+SS G EAR+++R CEGLVD+LL+ + + V   D D+K+VENCVC +RN
Sbjct: 518  VFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDNKSVENCVCIMRN 577

Query: 749  LSYRLELEVPQARLLGLNE---LDDLLGKESPSKDSEPSCWGKKKKKK------KRTPQE 799
            LSY +  EVP A      E   L   +G +   +D + SC+G KK K+      K+  + 
Sbjct: 578  LSYHVHKEVPGADRYQEAEPGPLGSAVGSQRRRRD-DASCFGGKKAKEEWFHQGKKDGEM 636

Query: 800  DQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWK 859
            D+      +P  +++ KG E+L+ P VV+ YL+LL ES N  TLE +AG+LQNLSAGNW 
Sbjct: 637  DRNFDTLDLPKRTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEAAAGALQNLSAGNWM 696

Query: 860  FAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVN 919
            +A YIRA VRKE+GLP+LVELL+ + D+VV +VA ALRN++LD RNK+LIG YAM +LV 
Sbjct: 697  WATYIRATVRKERGLPVLVELLQSETDKVVRAVAIALRNLSLDRRNKDLIGSYAMAELVR 756

Query: 920  RLPGGNGP----SVLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDR 975
             +     P    + L ++T+ A+   +HE+ S +++NA++L  + G+  LV +       
Sbjct: 757  NVRNAQAPPRPGACLEEDTVVAVLNTIHEIVSDSLDNARSLLQARGVPALVALV---ASS 813

Query: 976  SSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDRFKSHPSLSTTNQQ 1035
             S++  KAA+ VL T+W Y++LR   +KDGW +  F +  +T +  +    P     +  
Sbjct: 814  QSVREAKAASHVLQTVWSYKELRGTLQKDGWTKARFQSAAATAKGPKGALSP--GGFDDS 871

Query: 1036 MSPII------QSVGSTSSSPALLGIRDPRSEYDRTQPPMQYYNSQGDATHK---GLYPG 1086
              P++      +  GS    P      D  S  DR +   +  +S G+A+ K    L P 
Sbjct: 872  TLPLVDKSLEGEKTGSRDVIPMDALGPDGYSTVDRRERRPRGASSAGEASEKEPLKLDPS 931

Query: 1087 SSKPSP 1092
               P P
Sbjct: 932  RKAPPP 937



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 28/48 (58%), Positives = 35/48 (72%), Gaps = 4/48 (8%)

Query: 33 TATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAESPSIAS 80
          +A +ILASVKEQE +F+RLTR LE ER+ VA QLER    A+ P + S
Sbjct: 8  SAASILASVKEQEARFERLTRALEQERRHVALQLER----AQQPGMVS 51


>gi|146231975 catenin, delta 1 isoform 3A [Homo sapiens]
          Length = 832

 Score =  442 bits (1136), Expect = e-123
 Identities = 242/514 (47%), Positives = 339/514 (65%), Gaps = 11/514 (2%)

Query: 512  SIDSIQKD-PREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLG 570
            S+DS++K  P    WR PELPEVI ML  +  +V++NAAAYLQHLC+ ++KVK +V +L 
Sbjct: 248  SLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLK 307

Query: 571  GIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAE 630
            GI  LV LLDH   EV   ACGAL+N+ FG+  D NKIA+KN  G+PAL+RLLRK+ D +
Sbjct: 308  GIPVLVGLLDHPKKEVHLGACGALKNISFGRDQD-NKIAIKNCDGVPALVRLLRKARDMD 366

Query: 631  VRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVL 690
            + E++TG LWNLSS D++KM I+  AL  LT+ VI+PHSGW     +D      +   VL
Sbjct: 367  LTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVL 426

Query: 691  RNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLS 750
             NT GCLRN+SS   EAR+++R C+GLVD+L++++   +   D DSK VENCVC LRNLS
Sbjct: 427  TNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLS 486

Query: 751  YRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPG 810
            Y++  E+PQA         ++     P      SC+G KK K K+ P ED  +     P 
Sbjct: 487  YQVHREIPQAERY-QEAAPNVANNTGP---HAASCFGAKKGKGKK-PIEDPANDTVDFPK 541

Query: 811  LSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRK 870
             +   +G E+L+ P VV+ Y++LL ES  PA LE SAG++QNL AG W +  YIR+A+R+
Sbjct: 542  RTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQ 601

Query: 871  EKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGG--NGPS 928
            EK L  + +LL  +++RVV + + ALRN+A+D RNKELIGK+A+ +LV  LPGG  N   
Sbjct: 602  EKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSW 661

Query: 929  VLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVL 988
              S++T+ +I   ++EV ++N+E AK L ++ GIEKLV I K  G+RS  K V+AAA VL
Sbjct: 662  NFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKS-GNRSE-KEVRAAALVL 719

Query: 989  NTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDR 1022
             T+W Y++LR   +K+GW ++ F   ++   R +
Sbjct: 720  QTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQ 753


>gi|146231948 catenin, delta 1 isoform 3A [Homo sapiens]
          Length = 832

 Score =  442 bits (1136), Expect = e-123
 Identities = 242/514 (47%), Positives = 339/514 (65%), Gaps = 11/514 (2%)

Query: 512  SIDSIQKD-PREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLG 570
            S+DS++K  P    WR PELPEVI ML  +  +V++NAAAYLQHLC+ ++KVK +V +L 
Sbjct: 248  SLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLK 307

Query: 571  GIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAE 630
            GI  LV LLDH   EV   ACGAL+N+ FG+  D NKIA+KN  G+PAL+RLLRK+ D +
Sbjct: 308  GIPVLVGLLDHPKKEVHLGACGALKNISFGRDQD-NKIAIKNCDGVPALVRLLRKARDMD 366

Query: 631  VRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVL 690
            + E++TG LWNLSS D++KM I+  AL  LT+ VI+PHSGW     +D      +   VL
Sbjct: 367  LTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVL 426

Query: 691  RNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLS 750
             NT GCLRN+SS   EAR+++R C+GLVD+L++++   +   D DSK VENCVC LRNLS
Sbjct: 427  TNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLS 486

Query: 751  YRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPG 810
            Y++  E+PQA         ++     P      SC+G KK K K+ P ED  +     P 
Sbjct: 487  YQVHREIPQAERY-QEAAPNVANNTGP---HAASCFGAKKGKGKK-PIEDPANDTVDFPK 541

Query: 811  LSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRK 870
             +   +G E+L+ P VV+ Y++LL ES  PA LE SAG++QNL AG W +  YIR+A+R+
Sbjct: 542  RTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQ 601

Query: 871  EKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGG--NGPS 928
            EK L  + +LL  +++RVV + + ALRN+A+D RNKELIGK+A+ +LV  LPGG  N   
Sbjct: 602  EKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSW 661

Query: 929  VLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVL 988
              S++T+ +I   ++EV ++N+E AK L ++ GIEKLV I K  G+RS  K V+AAA VL
Sbjct: 662  NFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKS-GNRSE-KEVRAAALVL 719

Query: 989  NTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDR 1022
             T+W Y++LR   +K+GW ++ F   ++   R +
Sbjct: 720  QTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQ 753


>gi|146231994 catenin, delta 1 isoform 3A [Homo sapiens]
          Length = 832

 Score =  442 bits (1136), Expect = e-123
 Identities = 242/514 (47%), Positives = 339/514 (65%), Gaps = 11/514 (2%)

Query: 512  SIDSIQKD-PREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLG 570
            S+DS++K  P    WR PELPEVI ML  +  +V++NAAAYLQHLC+ ++KVK +V +L 
Sbjct: 248  SLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLK 307

Query: 571  GIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAE 630
            GI  LV LLDH   EV   ACGAL+N+ FG+  D NKIA+KN  G+PAL+RLLRK+ D +
Sbjct: 308  GIPVLVGLLDHPKKEVHLGACGALKNISFGRDQD-NKIAIKNCDGVPALVRLLRKARDMD 366

Query: 631  VRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVL 690
            + E++TG LWNLSS D++KM I+  AL  LT+ VI+PHSGW     +D      +   VL
Sbjct: 367  LTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVL 426

Query: 691  RNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLS 750
             NT GCLRN+SS   EAR+++R C+GLVD+L++++   +   D DSK VENCVC LRNLS
Sbjct: 427  TNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLS 486

Query: 751  YRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPG 810
            Y++  E+PQA         ++     P      SC+G KK K K+ P ED  +     P 
Sbjct: 487  YQVHREIPQAERY-QEAAPNVANNTGP---HAASCFGAKKGKGKK-PIEDPANDTVDFPK 541

Query: 811  LSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRK 870
             +   +G E+L+ P VV+ Y++LL ES  PA LE SAG++QNL AG W +  YIR+A+R+
Sbjct: 542  RTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQ 601

Query: 871  EKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGG--NGPS 928
            EK L  + +LL  +++RVV + + ALRN+A+D RNKELIGK+A+ +LV  LPGG  N   
Sbjct: 602  EKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSW 661

Query: 929  VLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVL 988
              S++T+ +I   ++EV ++N+E AK L ++ GIEKLV I K  G+RS  K V+AAA VL
Sbjct: 662  NFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKS-GNRSE-KEVRAAALVL 719

Query: 989  NTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDR 1022
             T+W Y++LR   +K+GW ++ F   ++   R +
Sbjct: 720  QTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQ 753


>gi|146231946 catenin, delta 1 isoform 3B [Homo sapiens]
          Length = 840

 Score =  442 bits (1136), Expect = e-123
 Identities = 242/514 (47%), Positives = 339/514 (65%), Gaps = 11/514 (2%)

Query: 512  SIDSIQKD-PREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLG 570
            S+DS++K  P    WR PELPEVI ML  +  +V++NAAAYLQHLC+ ++KVK +V +L 
Sbjct: 248  SLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLK 307

Query: 571  GIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAE 630
            GI  LV LLDH   EV   ACGAL+N+ FG+  D NKIA+KN  G+PAL+RLLRK+ D +
Sbjct: 308  GIPVLVGLLDHPKKEVHLGACGALKNISFGRDQD-NKIAIKNCDGVPALVRLLRKARDMD 366

Query: 631  VRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVL 690
            + E++TG LWNLSS D++KM I+  AL  LT+ VI+PHSGW     +D      +   VL
Sbjct: 367  LTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVL 426

Query: 691  RNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLS 750
             NT GCLRN+SS   EAR+++R C+GLVD+L++++   +   D DSK VENCVC LRNLS
Sbjct: 427  TNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLS 486

Query: 751  YRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPG 810
            Y++  E+PQA         ++     P      SC+G KK K K+ P ED  +     P 
Sbjct: 487  YQVHREIPQAERY-QEAAPNVANNTGP---HAASCFGAKKGKGKK-PIEDPANDTVDFPK 541

Query: 811  LSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRK 870
             +   +G E+L+ P VV+ Y++LL ES  PA LE SAG++QNL AG W +  YIR+A+R+
Sbjct: 542  RTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQ 601

Query: 871  EKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGG--NGPS 928
            EK L  + +LL  +++RVV + + ALRN+A+D RNKELIGK+A+ +LV  LPGG  N   
Sbjct: 602  EKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSW 661

Query: 929  VLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVL 988
              S++T+ +I   ++EV ++N+E AK L ++ GIEKLV I K  G+RS  K V+AAA VL
Sbjct: 662  NFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKS-GNRSE-KEVRAAALVL 719

Query: 989  NTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDR 1022
             T+W Y++LR   +K+GW ++ F   ++   R +
Sbjct: 720  QTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQ 753


>gi|146231991 catenin, delta 1 isoform 3AB [Homo sapiens]
          Length = 861

 Score =  442 bits (1136), Expect = e-123
 Identities = 242/514 (47%), Positives = 339/514 (65%), Gaps = 11/514 (2%)

Query: 512  SIDSIQKD-PREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLG 570
            S+DS++K  P    WR PELPEVI ML  +  +V++NAAAYLQHLC+ ++KVK +V +L 
Sbjct: 248  SLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLK 307

Query: 571  GIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAE 630
            GI  LV LLDH   EV   ACGAL+N+ FG+  D NKIA+KN  G+PAL+RLLRK+ D +
Sbjct: 308  GIPVLVGLLDHPKKEVHLGACGALKNISFGRDQD-NKIAIKNCDGVPALVRLLRKARDMD 366

Query: 631  VRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVL 690
            + E++TG LWNLSS D++KM I+  AL  LT+ VI+PHSGW     +D      +   VL
Sbjct: 367  LTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVL 426

Query: 691  RNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLS 750
             NT GCLRN+SS   EAR+++R C+GLVD+L++++   +   D DSK VENCVC LRNLS
Sbjct: 427  TNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLS 486

Query: 751  YRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPG 810
            Y++  E+PQA         ++     P      SC+G KK K K+ P ED  +     P 
Sbjct: 487  YQVHREIPQAERY-QEAAPNVANNTGP---HAASCFGAKKGKGKK-PIEDPANDTVDFPK 541

Query: 811  LSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRK 870
             +   +G E+L+ P VV+ Y++LL ES  PA LE SAG++QNL AG W +  YIR+A+R+
Sbjct: 542  RTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQ 601

Query: 871  EKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGG--NGPS 928
            EK L  + +LL  +++RVV + + ALRN+A+D RNKELIGK+A+ +LV  LPGG  N   
Sbjct: 602  EKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSW 661

Query: 929  VLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVL 988
              S++T+ +I   ++EV ++N+E AK L ++ GIEKLV I K  G+RS  K V+AAA VL
Sbjct: 662  NFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKS-GNRSE-KEVRAAALVL 719

Query: 989  NTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDR 1022
             T+W Y++LR   +K+GW ++ F   ++   R +
Sbjct: 720  QTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQ 753


>gi|146231942 catenin, delta 1 isoform 1A [Homo sapiens]
          Length = 933

 Score =  442 bits (1136), Expect = e-123
 Identities = 242/514 (47%), Positives = 339/514 (65%), Gaps = 11/514 (2%)

Query: 512  SIDSIQKD-PREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLG 570
            S+DS++K  P    WR PELPEVI ML  +  +V++NAAAYLQHLC+ ++KVK +V +L 
Sbjct: 349  SLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLK 408

Query: 571  GIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAE 630
            GI  LV LLDH   EV   ACGAL+N+ FG+  D NKIA+KN  G+PAL+RLLRK+ D +
Sbjct: 409  GIPVLVGLLDHPKKEVHLGACGALKNISFGRDQD-NKIAIKNCDGVPALVRLLRKARDMD 467

Query: 631  VRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVL 690
            + E++TG LWNLSS D++KM I+  AL  LT+ VI+PHSGW     +D      +   VL
Sbjct: 468  LTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVL 527

Query: 691  RNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLS 750
             NT GCLRN+SS   EAR+++R C+GLVD+L++++   +   D DSK VENCVC LRNLS
Sbjct: 528  TNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLS 587

Query: 751  YRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPG 810
            Y++  E+PQA         ++     P      SC+G KK K K+ P ED  +     P 
Sbjct: 588  YQVHREIPQAERY-QEAAPNVANNTGP---HAASCFGAKKGKGKK-PIEDPANDTVDFPK 642

Query: 811  LSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRK 870
             +   +G E+L+ P VV+ Y++LL ES  PA LE SAG++QNL AG W +  YIR+A+R+
Sbjct: 643  RTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQ 702

Query: 871  EKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGG--NGPS 928
            EK L  + +LL  +++RVV + + ALRN+A+D RNKELIGK+A+ +LV  LPGG  N   
Sbjct: 703  EKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSW 762

Query: 929  VLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVL 988
              S++T+ +I   ++EV ++N+E AK L ++ GIEKLV I K  G+RS  K V+AAA VL
Sbjct: 763  NFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKS-GNRSE-KEVRAAALVL 820

Query: 989  NTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDR 1022
             T+W Y++LR   +K+GW ++ F   ++   R +
Sbjct: 821  QTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQ 854



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 31/60 (51%), Positives = 45/60 (75%), Gaps = 3/60 (5%)

Query: 29 EPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAE--SPSIASTSSTEK 86
          E E+TA+ ILASVKEQE QF++LTR LE ER+ V++QLER R+  +  +P +A+ + T +
Sbjct: 5  EVESTAS-ILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDANPLMANGTLTRR 63


>gi|146231968 catenin, delta 1 isoform 1A [Homo sapiens]
          Length = 933

 Score =  442 bits (1136), Expect = e-123
 Identities = 242/514 (47%), Positives = 339/514 (65%), Gaps = 11/514 (2%)

Query: 512  SIDSIQKD-PREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLG 570
            S+DS++K  P    WR PELPEVI ML  +  +V++NAAAYLQHLC+ ++KVK +V +L 
Sbjct: 349  SLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLK 408

Query: 571  GIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAE 630
            GI  LV LLDH   EV   ACGAL+N+ FG+  D NKIA+KN  G+PAL+RLLRK+ D +
Sbjct: 409  GIPVLVGLLDHPKKEVHLGACGALKNISFGRDQD-NKIAIKNCDGVPALVRLLRKARDMD 467

Query: 631  VRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVL 690
            + E++TG LWNLSS D++KM I+  AL  LT+ VI+PHSGW     +D      +   VL
Sbjct: 468  LTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVL 527

Query: 691  RNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLS 750
             NT GCLRN+SS   EAR+++R C+GLVD+L++++   +   D DSK VENCVC LRNLS
Sbjct: 528  TNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLS 587

Query: 751  YRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPG 810
            Y++  E+PQA         ++     P      SC+G KK K K+ P ED  +     P 
Sbjct: 588  YQVHREIPQAERY-QEAAPNVANNTGP---HAASCFGAKKGKGKK-PIEDPANDTVDFPK 642

Query: 811  LSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRK 870
             +   +G E+L+ P VV+ Y++LL ES  PA LE SAG++QNL AG W +  YIR+A+R+
Sbjct: 643  RTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQ 702

Query: 871  EKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGG--NGPS 928
            EK L  + +LL  +++RVV + + ALRN+A+D RNKELIGK+A+ +LV  LPGG  N   
Sbjct: 703  EKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSW 762

Query: 929  VLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVL 988
              S++T+ +I   ++EV ++N+E AK L ++ GIEKLV I K  G+RS  K V+AAA VL
Sbjct: 763  NFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKS-GNRSE-KEVRAAALVL 820

Query: 989  NTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDR 1022
             T+W Y++LR   +K+GW ++ F   ++   R +
Sbjct: 821  QTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQ 854



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 31/60 (51%), Positives = 45/60 (75%), Gaps = 3/60 (5%)

Query: 29 EPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAE--SPSIASTSSTEK 86
          E E+TA+ ILASVKEQE QF++LTR LE ER+ V++QLER R+  +  +P +A+ + T +
Sbjct: 5  EVESTAS-ILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDANPLMANGTLTRR 63


>gi|146231938 catenin, delta 1 isoform 1A [Homo sapiens]
          Length = 933

 Score =  442 bits (1136), Expect = e-123
 Identities = 242/514 (47%), Positives = 339/514 (65%), Gaps = 11/514 (2%)

Query: 512  SIDSIQKD-PREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLG 570
            S+DS++K  P    WR PELPEVI ML  +  +V++NAAAYLQHLC+ ++KVK +V +L 
Sbjct: 349  SLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLK 408

Query: 571  GIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAE 630
            GI  LV LLDH   EV   ACGAL+N+ FG+  D NKIA+KN  G+PAL+RLLRK+ D +
Sbjct: 409  GIPVLVGLLDHPKKEVHLGACGALKNISFGRDQD-NKIAIKNCDGVPALVRLLRKARDMD 467

Query: 631  VRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVL 690
            + E++TG LWNLSS D++KM I+  AL  LT+ VI+PHSGW     +D      +   VL
Sbjct: 468  LTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVL 527

Query: 691  RNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLS 750
             NT GCLRN+SS   EAR+++R C+GLVD+L++++   +   D DSK VENCVC LRNLS
Sbjct: 528  TNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLS 587

Query: 751  YRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPG 810
            Y++  E+PQA         ++     P      SC+G KK K K+ P ED  +     P 
Sbjct: 588  YQVHREIPQAERY-QEAAPNVANNTGP---HAASCFGAKKGKGKK-PIEDPANDTVDFPK 642

Query: 811  LSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRK 870
             +   +G E+L+ P VV+ Y++LL ES  PA LE SAG++QNL AG W +  YIR+A+R+
Sbjct: 643  RTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQ 702

Query: 871  EKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGG--NGPS 928
            EK L  + +LL  +++RVV + + ALRN+A+D RNKELIGK+A+ +LV  LPGG  N   
Sbjct: 703  EKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSW 762

Query: 929  VLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVL 988
              S++T+ +I   ++EV ++N+E AK L ++ GIEKLV I K  G+RS  K V+AAA VL
Sbjct: 763  NFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKS-GNRSE-KEVRAAALVL 820

Query: 989  NTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDR 1022
             T+W Y++LR   +K+GW ++ F   ++   R +
Sbjct: 821  QTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQ 854



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 31/60 (51%), Positives = 45/60 (75%), Gaps = 3/60 (5%)

Query: 29 EPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAE--SPSIASTSSTEK 86
          E E+TA+ ILASVKEQE QF++LTR LE ER+ V++QLER R+  +  +P +A+ + T +
Sbjct: 5  EVESTAS-ILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDANPLMANGTLTRR 63


>gi|10835010 catenin, delta 1 isoform 1B [Homo sapiens]
          Length = 941

 Score =  442 bits (1136), Expect = e-123
 Identities = 242/514 (47%), Positives = 339/514 (65%), Gaps = 11/514 (2%)

Query: 512  SIDSIQKD-PREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLG 570
            S+DS++K  P    WR PELPEVI ML  +  +V++NAAAYLQHLC+ ++KVK +V +L 
Sbjct: 349  SLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLK 408

Query: 571  GIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAE 630
            GI  LV LLDH   EV   ACGAL+N+ FG+  D NKIA+KN  G+PAL+RLLRK+ D +
Sbjct: 409  GIPVLVGLLDHPKKEVHLGACGALKNISFGRDQD-NKIAIKNCDGVPALVRLLRKARDMD 467

Query: 631  VRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVL 690
            + E++TG LWNLSS D++KM I+  AL  LT+ VI+PHSGW     +D      +   VL
Sbjct: 468  LTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVL 527

Query: 691  RNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLS 750
             NT GCLRN+SS   EAR+++R C+GLVD+L++++   +   D DSK VENCVC LRNLS
Sbjct: 528  TNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLS 587

Query: 751  YRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPG 810
            Y++  E+PQA         ++     P      SC+G KK K K+ P ED  +     P 
Sbjct: 588  YQVHREIPQAERY-QEAAPNVANNTGP---HAASCFGAKKGKGKK-PIEDPANDTVDFPK 642

Query: 811  LSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRK 870
             +   +G E+L+ P VV+ Y++LL ES  PA LE SAG++QNL AG W +  YIR+A+R+
Sbjct: 643  RTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQ 702

Query: 871  EKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGG--NGPS 928
            EK L  + +LL  +++RVV + + ALRN+A+D RNKELIGK+A+ +LV  LPGG  N   
Sbjct: 703  EKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSW 762

Query: 929  VLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVL 988
              S++T+ +I   ++EV ++N+E AK L ++ GIEKLV I K  G+RS  K V+AAA VL
Sbjct: 763  NFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKS-GNRSE-KEVRAAALVL 820

Query: 989  NTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDR 1022
             T+W Y++LR   +K+GW ++ F   ++   R +
Sbjct: 821  QTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQ 854



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 31/60 (51%), Positives = 45/60 (75%), Gaps = 3/60 (5%)

Query: 29 EPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAE--SPSIASTSSTEK 86
          E E+TA+ ILASVKEQE QF++LTR LE ER+ V++QLER R+  +  +P +A+ + T +
Sbjct: 5  EVESTAS-ILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDANPLMANGTLTRR 63


>gi|146231962 catenin, delta 1 isoform 1AB [Homo sapiens]
          Length = 962

 Score =  442 bits (1136), Expect = e-123
 Identities = 242/514 (47%), Positives = 339/514 (65%), Gaps = 11/514 (2%)

Query: 512  SIDSIQKD-PREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLG 570
            S+DS++K  P    WR PELPEVI ML  +  +V++NAAAYLQHLC+ ++KVK +V +L 
Sbjct: 349  SLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLK 408

Query: 571  GIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAE 630
            GI  LV LLDH   EV   ACGAL+N+ FG+  D NKIA+KN  G+PAL+RLLRK+ D +
Sbjct: 409  GIPVLVGLLDHPKKEVHLGACGALKNISFGRDQD-NKIAIKNCDGVPALVRLLRKARDMD 467

Query: 631  VRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVL 690
            + E++TG LWNLSS D++KM I+  AL  LT+ VI+PHSGW     +D      +   VL
Sbjct: 468  LTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVL 527

Query: 691  RNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLS 750
             NT GCLRN+SS   EAR+++R C+GLVD+L++++   +   D DSK VENCVC LRNLS
Sbjct: 528  TNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLS 587

Query: 751  YRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPG 810
            Y++  E+PQA         ++     P      SC+G KK K K+ P ED  +     P 
Sbjct: 588  YQVHREIPQAERY-QEAAPNVANNTGP---HAASCFGAKKGKGKK-PIEDPANDTVDFPK 642

Query: 811  LSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRK 870
             +   +G E+L+ P VV+ Y++LL ES  PA LE SAG++QNL AG W +  YIR+A+R+
Sbjct: 643  RTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQ 702

Query: 871  EKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGG--NGPS 928
            EK L  + +LL  +++RVV + + ALRN+A+D RNKELIGK+A+ +LV  LPGG  N   
Sbjct: 703  EKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQQNSSW 762

Query: 929  VLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVL 988
              S++T+ +I   ++EV ++N+E AK L ++ GIEKLV I K  G+RS  K V+AAA VL
Sbjct: 763  NFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKS-GNRSE-KEVRAAALVL 820

Query: 989  NTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDR 1022
             T+W Y++LR   +K+GW ++ F   ++   R +
Sbjct: 821  QTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQ 854



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 31/60 (51%), Positives = 45/60 (75%), Gaps = 3/60 (5%)

Query: 29 EPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAE--SPSIASTSSTEK 86
          E E+TA+ ILASVKEQE QF++LTR LE ER+ V++QLER R+  +  +P +A+ + T +
Sbjct: 5  EVESTAS-ILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDANPLMANGTLTRR 63


>gi|146231977 catenin, delta 1 isoform 3AC [Homo sapiens]
          Length = 838

 Score =  439 bits (1128), Expect = e-122
 Identities = 241/519 (46%), Positives = 339/519 (65%), Gaps = 15/519 (2%)

Query: 512  SIDSIQKD-PREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLG 570
            S+DS++K  P    WR PELPEVI ML  +  +V++NAAAYLQHLC+ ++KVK +V +L 
Sbjct: 248  SLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLK 307

Query: 571  GIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAE 630
            GI  LV LLDH   EV   ACGAL+N+ FG+  D NKIA+KN  G+PAL+RLLRK+ D +
Sbjct: 308  GIPVLVGLLDHPKKEVHLGACGALKNISFGRDQD-NKIAIKNCDGVPALVRLLRKARDMD 366

Query: 631  VRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVL 690
            + E++TG LWNLSS D++KM I+  AL  LT+ VI+PHSGW     +D      +   VL
Sbjct: 367  LTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVL 426

Query: 691  RNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLS 750
             NT GCLRN+SS   EAR+++R C+GLVD+L++++   +   D DSK VENCVC LRNLS
Sbjct: 427  TNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLS 486

Query: 751  YRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKK-----KKRTPQEDQWDGV 805
            Y++  E+PQA         ++     P      SC+G KK K     + + P ED  +  
Sbjct: 487  YQVHREIPQAERY-QEAAPNVANNTGP---HAASCFGAKKGKDEWFSRGKKPIEDPANDT 542

Query: 806  GPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIR 865
               P  +   +G E+L+ P VV+ Y++LL ES  PA LE SAG++QNL AG W +  YIR
Sbjct: 543  VDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIR 602

Query: 866  AAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGG- 924
            +A+R+EK L  + +LL  +++RVV + + ALRN+A+D RNKELIGK+A+ +LV  LPGG 
Sbjct: 603  SALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQ 662

Query: 925  -NGPSVLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKA 983
             N     S++T+ +I   ++EV ++N+E AK L ++ GIEKLV I K  G+RS  K V+A
Sbjct: 663  QNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKS-GNRSE-KEVRA 720

Query: 984  AAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDR 1022
            AA VL T+W Y++LR   +K+GW ++ F   ++   R +
Sbjct: 721  AALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQ 759


>gi|146231970 catenin, delta 1 isoform 3ABC [Homo sapiens]
          Length = 867

 Score =  439 bits (1128), Expect = e-122
 Identities = 241/519 (46%), Positives = 339/519 (65%), Gaps = 15/519 (2%)

Query: 512  SIDSIQKD-PREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLG 570
            S+DS++K  P    WR PELPEVI ML  +  +V++NAAAYLQHLC+ ++KVK +V +L 
Sbjct: 248  SLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLK 307

Query: 571  GIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAE 630
            GI  LV LLDH   EV   ACGAL+N+ FG+  D NKIA+KN  G+PAL+RLLRK+ D +
Sbjct: 308  GIPVLVGLLDHPKKEVHLGACGALKNISFGRDQD-NKIAIKNCDGVPALVRLLRKARDMD 366

Query: 631  VRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVL 690
            + E++TG LWNLSS D++KM I+  AL  LT+ VI+PHSGW     +D      +   VL
Sbjct: 367  LTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVL 426

Query: 691  RNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLS 750
             NT GCLRN+SS   EAR+++R C+GLVD+L++++   +   D DSK VENCVC LRNLS
Sbjct: 427  TNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLS 486

Query: 751  YRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKK-----KKRTPQEDQWDGV 805
            Y++  E+PQA         ++     P      SC+G KK K     + + P ED  +  
Sbjct: 487  YQVHREIPQAERY-QEAAPNVANNTGP---HAASCFGAKKGKDEWFSRGKKPIEDPANDT 542

Query: 806  GPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIR 865
               P  +   +G E+L+ P VV+ Y++LL ES  PA LE SAG++QNL AG W +  YIR
Sbjct: 543  VDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIR 602

Query: 866  AAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGG- 924
            +A+R+EK L  + +LL  +++RVV + + ALRN+A+D RNKELIGK+A+ +LV  LPGG 
Sbjct: 603  SALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQ 662

Query: 925  -NGPSVLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKA 983
             N     S++T+ +I   ++EV ++N+E AK L ++ GIEKLV I K  G+RS  K V+A
Sbjct: 663  QNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKS-GNRSE-KEVRA 720

Query: 984  AAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDR 1022
            AA VL T+W Y++LR   +K+GW ++ F   ++   R +
Sbjct: 721  AALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQ 759


>gi|146231940 catenin, delta 1 isoform 1ABC [Homo sapiens]
          Length = 968

 Score =  439 bits (1128), Expect = e-122
 Identities = 241/519 (46%), Positives = 339/519 (65%), Gaps = 15/519 (2%)

Query: 512  SIDSIQKD-PREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLG 570
            S+DS++K  P    WR PELPEVI ML  +  +V++NAAAYLQHLC+ ++KVK +V +L 
Sbjct: 349  SLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLK 408

Query: 571  GIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAE 630
            GI  LV LLDH   EV   ACGAL+N+ FG+  D NKIA+KN  G+PAL+RLLRK+ D +
Sbjct: 409  GIPVLVGLLDHPKKEVHLGACGALKNISFGRDQD-NKIAIKNCDGVPALVRLLRKARDMD 467

Query: 631  VRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVL 690
            + E++TG LWNLSS D++KM I+  AL  LT+ VI+PHSGW     +D      +   VL
Sbjct: 468  LTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVL 527

Query: 691  RNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLS 750
             NT GCLRN+SS   EAR+++R C+GLVD+L++++   +   D DSK VENCVC LRNLS
Sbjct: 528  TNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLS 587

Query: 751  YRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKK-----KKRTPQEDQWDGV 805
            Y++  E+PQA         ++     P      SC+G KK K     + + P ED  +  
Sbjct: 588  YQVHREIPQAERY-QEAAPNVANNTGP---HAASCFGAKKGKDEWFSRGKKPIEDPANDT 643

Query: 806  GPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIR 865
               P  +   +G E+L+ P VV+ Y++LL ES  PA LE SAG++QNL AG W +  YIR
Sbjct: 644  VDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIR 703

Query: 866  AAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGG- 924
            +A+R+EK L  + +LL  +++RVV + + ALRN+A+D RNKELIGK+A+ +LV  LPGG 
Sbjct: 704  SALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGGQ 763

Query: 925  -NGPSVLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKA 983
             N     S++T+ +I   ++EV ++N+E AK L ++ GIEKLV I K  G+RS  K V+A
Sbjct: 764  QNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKS-GNRSE-KEVRA 821

Query: 984  AAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDR 1022
            AA VL T+W Y++LR   +K+GW ++ F   ++   R +
Sbjct: 822  AALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQ 860



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 31/60 (51%), Positives = 45/60 (75%), Gaps = 3/60 (5%)

Query: 29 EPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAE--SPSIASTSSTEK 86
          E E+TA+ ILASVKEQE QF++LTR LE ER+ V++QLER R+  +  +P +A+ + T +
Sbjct: 5  EVESTAS-ILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDANPLMANGTLTRR 63


>gi|148664186 plakophilin 2 isoform 2a [Homo sapiens]
          Length = 837

 Score =  295 bits (754), Expect = 2e-79
 Identities = 176/489 (35%), Positives = 282/489 (57%), Gaps = 23/489 (4%)

Query: 530  LPEVIHMLQ--HQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEVQ 587
            L   + ML+  H  PS  + AA ++QH CF  ++ +  V +L GI  L+ LL  +  +VQ
Sbjct: 353  LERAVSMLEADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQ 412

Query: 588  KNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDA 647
            +  CGALRNLVF    ++NK+ +  + G+P LL++L+++ D E ++ +TG+LWNLSS D 
Sbjct: 413  RAVCGALRNLVF--EDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQITGLLWNLSSNDK 470

Query: 648  VKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKI-KFQTSLVLRNTTGCLRNLSSAGEE 706
            +K  +I +AL TLT  +I+P SGW    +   + +  F    +  N TGCLRN+SSAG +
Sbjct: 471  LKNLMITEALLTLTENIIIPFSGWPEGDYPKANGLLDFD---IFYNVTGCLRNMSSAGAD 527

Query: 707  ARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLN 766
             RK MR C+GL+DSL++ +   +     D K  ENCVC L NLSY+LE E+P+     + 
Sbjct: 528  GRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATENCVCILHNLSYQLEAELPEKYSQNI- 586

Query: 767  ELDDLLGKESPSKDSEPS--CWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHP 824
                 +   +   D+  S  C+G + +K K     +Q+  V P+P    +PKGVE LWH 
Sbjct: 587  ----YIQNRNIQTDNNKSIGCFGSRSRKVK-----EQYQDV-PMPEEKSNPKGVEWLWHS 636

Query: 825  SVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYI-RAAVRKEKGLPILVELLRM 883
             V++ YL+L+A+S    T E S G+LQNL+AG+      + +  V+KE GL    ++L +
Sbjct: 637  IVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHV 696

Query: 884  DNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSVLSDETMAAICCALH 943
             +  V  +  + LRN++ ++  +  I K  + DLV+ +P     + L  ET A+ C  L+
Sbjct: 697  GDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIPDTVPSTDLLIETTASACYTLN 756

Query: 944  EVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKK 1003
             +   + +NA+ L ++GGI+K++ I+ G    S+ K  KAA+ +L +LW + +L   YKK
Sbjct: 757  NIIQNSYQNARDLLNTGGIQKIMAISAGDAYASN-KASKAASVLLYSLWAHTELHHAYKK 815

Query: 1004 DGWNQNHFI 1012
              + +  F+
Sbjct: 816  AQFKKTDFV 824


>gi|148664226 plakophilin 2 isoform 2b [Homo sapiens]
          Length = 881

 Score =  273 bits (699), Expect = 5e-73
 Identities = 176/533 (33%), Positives = 282/533 (52%), Gaps = 67/533 (12%)

Query: 530  LPEVIHMLQ--HQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEVQ 587
            L   + ML+  H  PS  + AA ++QH CF  ++ +  V +L GI  L+ LL  +  +VQ
Sbjct: 353  LERAVSMLEADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQ 412

Query: 588  KNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVT----------- 636
            +  CGALRNLVF    ++NK+ +  + G+P LL++L+++ D E ++ +T           
Sbjct: 413  RAVCGALRNLVF--EDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQITDHTVNLRSRNG 470

Query: 637  ---------------------------------GVLWNLSSCDAVKMTIIRDALSTLTNT 663
                                             G+LWNLSS D +K  +I +AL TLT  
Sbjct: 471  WPGAVAHACNPSTLGGQGGRITRSGVRDQPDQHGLLWNLSSNDKLKNLMITEALLTLTEN 530

Query: 664  VIVPHSGWNNSSFDDDHKI-KFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLL 722
            +I+P SGW    +   + +  F    +  N TGCLRN+SSAG + RK MR C+GL+DSL+
Sbjct: 531  IIIPFSGWPEGDYPKANGLLDFD---IFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLV 587

Query: 723  YVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKDSE 782
            + +   +     D K  ENCVC L NLSY+LE E+P+     +      +   +   D+ 
Sbjct: 588  HYVRGTIADYQPDDKATENCVCILHNLSYQLEAELPEKYSQNI-----YIQNRNIQTDNN 642

Query: 783  PS--CWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNP 840
             S  C+G + +K K     +Q+  V P+P    +PKGVE LWH  V++ YL+L+A+S   
Sbjct: 643  KSIGCFGSRSRKVK-----EQYQDV-PMPEEKSNPKGVEWLWHSIVIRMYLSLIAKSVRN 696

Query: 841  ATLEGSAGSLQNLSAGNWKFAAYI-RAAVRKEKGLPILVELLRMDNDRVVSSVATALRNM 899
             T E S G+LQNL+AG+      + +  V+KE GL    ++L + +  V  +  + LRN+
Sbjct: 697  YTQEASLGALQNLTAGSGPMPTSVAQTVVQKESGLQHTRKMLHVGDPSVKKTAISLLRNL 756

Query: 900  ALDVRNKELIGKYAMRDLVNRLPGGNGPSVLSDETMAAICCALHEVTSKNMENAKALADS 959
            + ++  +  I K  + DLV+ +P     + L  ET A+ C  L+ +   + +NA+ L ++
Sbjct: 757  SRNLSLQNEIAKETLPDLVSIIPDTVPSTDLLIETTASACYTLNNIIQNSYQNARDLLNT 816

Query: 960  GGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFI 1012
            GGI+K++ I+ G    S+ K  KAA+ +L +LW + +L   YKK  + +  F+
Sbjct: 817  GGIQKIMAISAGDAYASN-KASKAASVLLYSLWAHTELHHAYKKAQFKKTDFV 868


>gi|53729344 plakophilin 1 isoform 1a [Homo sapiens]
          Length = 726

 Score =  273 bits (697), Expect = 9e-73
 Identities = 168/482 (34%), Positives = 262/482 (54%), Gaps = 22/482 (4%)

Query: 530  LPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEVQKN 589
            +P+ +  L  Q    QA  A Y+QH CF D   K +V +LGGI  LVDLL      VQ+ 
Sbjct: 247  IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306

Query: 590  ACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVK 649
            A GALRNLVF  +T  NK+  +   GI   + LLR++ +AE+++ +TG+LWNLSS D +K
Sbjct: 307  AAGALRNLVFRSTT--NKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELK 364

Query: 650  MTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARK 709
              +I DAL  L + VI+P SGW + + +   ++      V  N TGCLRNLSSA +  R+
Sbjct: 365  EELIADALPVLADRVIIPFSGWCDGNSNMSREV--VDPEVFFNATGCLRNLSSA-DAGRQ 421

Query: 710  QMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVP-QARLLGLNEL 768
             MR+  GL+DSL+  +  CV  S  D K+VENC+C L NLSYRL+ EVP + R L  N  
Sbjct: 422  TMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYN-- 479

Query: 769  DDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVK 828
                 + + ++ S   C+  K  K      +       P+P    +PKG   L+H   ++
Sbjct: 480  ----ARNAYTEKSSTGCFSNKSDKMMNNNYD------CPLPEEETNPKGSGWLYHSDAIR 529

Query: 829  PYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAV-RKEKGLPILVELLRMDNDR 887
             YL L+ +S   ATLE  AG+LQNL+A     ++ +   +  KEKGLP +  LL+  N  
Sbjct: 530  TYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSD 589

Query: 888  VVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSVLSDETMAAICCALHEVTS 947
            VV S A+ L NM+       ++G     ++   L    G +  S++ +++ C  +  + +
Sbjct: 590  VVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA 649

Query: 948  KNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWN 1007
               + AK    S  +  ++N+ +     +S K  +AA  +L+ +W  ++L+ + ++ G++
Sbjct: 650  SQPQLAKQYFSSSMLNNIINLCR---SSASPKAAEAARLLLSDMWSSKELQGVLRQQGFD 706

Query: 1008 QN 1009
            +N
Sbjct: 707  RN 708


>gi|169218113 PREDICTED: similar to plakophilin 1, partial [Homo
            sapiens]
          Length = 625

 Score =  273 bits (697), Expect = 9e-73
 Identities = 168/482 (34%), Positives = 262/482 (54%), Gaps = 22/482 (4%)

Query: 530  LPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEVQKN 589
            +P+ +  L  Q    QA  A Y+QH CF D   K +V +LGGI  LVDLL      VQ+ 
Sbjct: 146  IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 205

Query: 590  ACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVK 649
            A GALRNLVF  +T  NK+  +   GI   + LLR++ +AE+++ +TG+LWNLSS D +K
Sbjct: 206  AAGALRNLVFRSTT--NKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELK 263

Query: 650  MTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARK 709
              +I DAL  L + VI+P SGW + + +   ++      V  N TGCLRNLSSA +  R+
Sbjct: 264  EELIADALPVLADRVIIPFSGWCDGNSNMSREV--VDPEVFFNATGCLRNLSSA-DAGRQ 320

Query: 710  QMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVP-QARLLGLNEL 768
             MR+  GL+DSL+  +  CV  S  D K+VENC+C L NLSYRL+ EVP + R L  N  
Sbjct: 321  TMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYN-- 378

Query: 769  DDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVK 828
                 + + ++ S   C+  K  K      +       P+P    +PKG   L+H   ++
Sbjct: 379  ----ARNAYTEKSSTGCFSNKSDKMMNNNYD------CPLPEEETNPKGSGWLYHSDAIR 428

Query: 829  PYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAV-RKEKGLPILVELLRMDNDR 887
             YL L+ +S   ATLE  AG+LQNL+A     ++ +   +  KEKGLP +  LL+  N  
Sbjct: 429  TYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSD 488

Query: 888  VVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSVLSDETMAAICCALHEVTS 947
            VV S A+ L NM+       ++G     ++   L    G +  S++ +++ C  +  + +
Sbjct: 489  VVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA 548

Query: 948  KNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWN 1007
               + AK    S  +  ++N+ +     +S K  +AA  +L+ +W  ++L+ + ++ G++
Sbjct: 549  SQPQLAKQYFSSSMLNNIINLCR---SSASPKAAEAARLLLSDMWSSKELQGVLRQQGFD 605

Query: 1008 QN 1009
            +N
Sbjct: 606  RN 607


>gi|53729346 plakophilin 1 isoform 1b [Homo sapiens]
          Length = 747

 Score =  260 bits (665), Expect = 5e-69
 Identities = 168/503 (33%), Positives = 262/503 (52%), Gaps = 43/503 (8%)

Query: 530  LPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEVQKN 589
            +P+ +  L  Q    QA  A Y+QH CF D   K +V +LGGI  LVDLL      VQ+ 
Sbjct: 247  IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQA 306

Query: 590  ACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVK 649
            A GALRNLVF  +T  NK+  +   GI   + LLR++ +AE+++ +TG+LWNLSS D +K
Sbjct: 307  AAGALRNLVFRSTT--NKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELK 364

Query: 650  MTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLR----------- 698
              +I DAL  L + VI+P SGW + + +   ++      V  N TGCLR           
Sbjct: 365  EELIADALPVLADRVIIPFSGWCDGNSNMSREV--VDPEVFFNATGCLRKRLGMRELLAL 422

Query: 699  ----------NLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRN 748
                      NLSSA +  R+ MR+  GL+DSL+  +  CV  S  D K+VENC+C L N
Sbjct: 423  VPQRATSSRVNLSSA-DAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHN 481

Query: 749  LSYRLELEVP-QARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGP 807
            LSYRL+ EVP + R L  N       + + ++ S   C+  K  K      +       P
Sbjct: 482  LSYRLDAEVPTRYRQLEYN------ARNAYTEKSSTGCFSNKSDKMMNNNYD------CP 529

Query: 808  IPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAA 867
            +P    +PKG   L+H   ++ YL L+ +S   ATLE  AG+LQNL+A     ++ +   
Sbjct: 530  LPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQL 589

Query: 868  V-RKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNG 926
            +  KEKGLP +  LL+  N  VV S A+ L NM+       ++G     ++   L    G
Sbjct: 590  IGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTG 649

Query: 927  PSVLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQ 986
             +  S++ +++ C  +  + +   + AK    S  +  ++N+ +     +S K  +AA  
Sbjct: 650  NTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCR---SSASPKAAEAARL 706

Query: 987  VLNTLWQYRDLRSIYKKDGWNQN 1009
            +L+ +W  ++L+ + ++ G+++N
Sbjct: 707  LLSDMWSSKELQGVLRQQGFDRN 729


>gi|6005830 plakophilin 3 [Homo sapiens]
          Length = 797

 Score =  259 bits (661), Expect = 1e-68
 Identities = 169/492 (34%), Positives = 260/492 (52%), Gaps = 16/492 (3%)

Query: 527  DPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEV 586
            D +LP  +  L    P++Q   AAY+QH C+ D   K +   L  +  LV L +H   EV
Sbjct: 318  DIDLPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEV 377

Query: 587  QKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCD 646
            Q++A GA+RNL++  +  +NK+A+    GI  LLR LR+  D E+R+ VTG+LWNLSS D
Sbjct: 378  QRHATGAMRNLIYDNA--DNKLALVEENGIFELLRTLREQ-DDELRKNVTGILWNLSSSD 434

Query: 647  AVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEE 706
             +K  + RD L  LT+ V+ P SG         +  + +   +  N TG LRNLSSA + 
Sbjct: 435  HLKDRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAE---IFYNATGFLRNLSSASQA 491

Query: 707  ARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLN 766
             R++MR C GLVD+L+  I+  ++    + K+VEN VC LRNLSYRL  E+P + L  L 
Sbjct: 492  TRQKMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLE 551

Query: 767  ELD--DLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHP 824
                 DL G           C+  + ++ +  P             +SK PKG+E LW P
Sbjct: 552  GRGRRDLAG---APPGEVVGCFTPQSRRLRELPLAAD---ALTFAEVSKDPKGLEWLWSP 605

Query: 825  SVVKPYLTLLAESS-NPATLEGSAGSLQNLSAGNWKFAAYI-RAAVRKEKGLPILVELLR 882
             +V  Y  LL     N  T E +AG+LQN++AG+ ++A  + R A+ +E+ L  L++ +R
Sbjct: 606  QIVGLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLALEQERILNPLLDRVR 665

Query: 883  MDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSVLSDETMAAICCAL 942
              +   + S+   +RN++ + RNK+ +    +  L+ +LPG  G      E +  I   L
Sbjct: 666  TADHHQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKSPPAEVLVNIIAVL 725

Query: 943  HEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYK 1002
            + +   +   A+ L    G+ KL+ I K R    S K  +AA+ +L  LWQY  L   ++
Sbjct: 726  NNLVVASPIAARDLLYFDGLRKLIFIKKKRDSPDSEKSSRAASSLLANLWQYNKLHRDFR 785

Query: 1003 KDGWNQNHFITP 1014
              G+ +  F+ P
Sbjct: 786  AKGYRKEDFLGP 797


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 70/286 (24%), Positives = 114/286 (39%), Gaps = 23/286 (8%)

Query: 73  AESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDAVQPNNYLIRTEPEQGTLYSPEQTS 132
           +ES + +S +ST  +     +  P++G S    SD+   ++          +  S E ++
Sbjct: 108 SESSTTSSGASTATN---SESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEAST 164

Query: 133 LHESEGSLGNSRSSTQMNSYSDSGYQEAGSFHNSQN--VSKADNRQQHSFIGSTNNHVVR 190
              SE S  +S +ST  NS S +    A +  NS++   S   +   +S   +T+N    
Sbjct: 165 ATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGT 224

Query: 191 NSRAEGQTLVQPSVANRAMRRVSSVPS-----RAQSPSYVISTGVSPSRGSLRTSLGSGF 245
            + +E  T    S A+ A    SS PS        S S   S+G   +  S  +++ SG 
Sbjct: 225 ATNSESST--TSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGI 282

Query: 246 GSPSVTDPRPLNPS--------AYSSTTLPAARAASPYSQRPASPTAIRRIGSVTSRQTS 297
              +VT+     PS        + SSTT   A  A+       S  A     S +S  +S
Sbjct: 283 S--TVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSS 340

Query: 298 NPNGPT-PQYQTTARVGSPLTLTDAQTRVASPSQGQVGSSSPKRSG 342
             +  T  +  TT+   S  T + + T  +  S      SS   SG
Sbjct: 341 GASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSG 386



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 72/351 (20%), Positives = 131/351 (37%), Gaps = 15/351 (4%)

Query: 7   ASLVEEGQPQTRQEAASTGPGMEPETTATTI-LASVKEQELQFQRLTRELEVERQIVASQ 65
           AS        T    AST    +  TT++    A+  E        +     E   V+S+
Sbjct: 132 ASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSR 191

Query: 66  LERCRLGAESPSIASTSSTEKSFPWRSTD-----VPNTGVSKPRVSDAVQPNNYLIRTEP 120
                  +ES + +S +ST  +   R+T        N+  S      +   N+       
Sbjct: 192 ASTAT-NSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSS 250

Query: 121 EQGTLYSPEQTSLHESEGSLGNSRSSTQMNSYSDSGYQEAGSFHNSQNVSKADNRQQHSF 180
             GT  + E ++     G+  NS SST  +  S     E+ +  +  N +        S 
Sbjct: 251 GAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTAT----NSESS 306

Query: 181 IGSTNNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPSRA-QSPSYVISTGVSPSRGSLRT 239
             S+  +   NS +   +    +  N      SS  S A  S S   S+G S +  S  +
Sbjct: 307 TTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSS 366

Query: 240 SLGSGFGSPSVTDPRPLNPSAYSSTTLPAARAASPYSQRPASPTAIRRIGSVT---SRQT 296
           +  SG  + + ++   ++  A ++TT  ++  +S  S    S ++    G+ T   S  +
Sbjct: 367 TTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNSESS 426

Query: 297 SNPNGPTPQYQTTARVGSPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVP 347
           +  +G      + + V S  + T A T + + S     + S  + G + VP
Sbjct: 427 TTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSEAKPGGSLVP 477



 Score = 36.2 bits (82), Expect = 0.19
 Identities = 50/245 (20%), Positives = 91/245 (37%), Gaps = 10/245 (4%)

Query: 6   QASLVEEGQPQTRQEAASTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQIVASQ 65
           +AS     +  T    AST    E  TT+     +   +                   S 
Sbjct: 191 RASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSS 250

Query: 66  LERCRLGAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDAVQPNNYL-IRTEPEQGT 124
                  +ES + +S + T  +     +   ++G+S    S++  P++     T  E  T
Sbjct: 251 GAGTATNSESSTTSSGAGTATN---SESSTVSSGISTVTNSESSTPSSGANTATNSESST 307

Query: 125 LYSPEQTSLHESEGSLGNSRSSTQMNSYSDSGYQEAGSFHNSQNVSKADNRQQHSFIGST 184
             S   T+ + S+ S  +S +ST  NS S +    A +  NS++ + +      +  GS+
Sbjct: 308 TSSGANTATN-SDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSS 366

Query: 185 NNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPS-----RAQSPSYVISTGVSPSRGSLRT 239
                 ++    ++    S A+ A    SS  S        S S  +S+G S +  S  +
Sbjct: 367 TTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNSESS 426

Query: 240 SLGSG 244
           +  SG
Sbjct: 427 TTSSG 431


>gi|189011568 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 56/220 (25%), Positives = 92/220 (41%), Gaps = 27/220 (12%)

Query: 539 HQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGG-IKHLVDLLDHRVLEVQKNACGALRNL 597
           H   +++  A   L +L FGD   K  +C + G ++ LV  L     ++Q+     LRNL
Sbjct: 492 HYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNL 551

Query: 598 VFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSS-CDAVKMTI--IR 654
            +    +  K  ++ VG + AL+    +       + V   LWNLS+ C   K  I  + 
Sbjct: 552 SWRADVNSKK-TLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVD 610

Query: 655 DALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSS--AGEEARKQMR 712
            AL+ L  T+               ++ +  T  ++ +  G LRN+SS  A  E  +Q+ 
Sbjct: 611 GALAFLVGTL--------------TYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQIL 656

Query: 713 SCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYR 752
                + +LL       +   +    V N   TL NLS R
Sbjct: 657 RENNCLQTLLQ------HLKSHSLTIVSNACGTLWNLSAR 690


>gi|189011566 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 56/220 (25%), Positives = 92/220 (41%), Gaps = 27/220 (12%)

Query: 539 HQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGG-IKHLVDLLDHRVLEVQKNACGALRNL 597
           H   +++  A   L +L FGD   K  +C + G ++ LV  L     ++Q+     LRNL
Sbjct: 492 HYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNL 551

Query: 598 VFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSS-CDAVKMTI--IR 654
            +    +  K  ++ VG + AL+    +       + V   LWNLS+ C   K  I  + 
Sbjct: 552 SWRADVNSKK-TLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVD 610

Query: 655 DALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSS--AGEEARKQMR 712
            AL+ L  T+               ++ +  T  ++ +  G LRN+SS  A  E  +Q+ 
Sbjct: 611 GALAFLVGTL--------------TYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQIL 656

Query: 713 SCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYR 752
                + +LL       +   +    V N   TL NLS R
Sbjct: 657 RENNCLQTLLQ------HLKSHSLTIVSNACGTLWNLSAR 690


>gi|53759122 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 56/220 (25%), Positives = 92/220 (41%), Gaps = 27/220 (12%)

Query: 539 HQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGG-IKHLVDLLDHRVLEVQKNACGALRNL 597
           H   +++  A   L +L FGD   K  +C + G ++ LV  L     ++Q+     LRNL
Sbjct: 492 HYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNL 551

Query: 598 VFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSS-CDAVKMTI--IR 654
            +    +  K  ++ VG + AL+    +       + V   LWNLS+ C   K  I  + 
Sbjct: 552 SWRADVNSKK-TLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVD 610

Query: 655 DALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSS--AGEEARKQMR 712
            AL+ L  T+               ++ +  T  ++ +  G LRN+SS  A  E  +Q+ 
Sbjct: 611 GALAFLVGTL--------------TYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQIL 656

Query: 713 SCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYR 752
                + +LL       +   +    V N   TL NLS R
Sbjct: 657 RENNCLQTLLQ------HLKSHSLTIVSNACGTLWNLSAR 690


>gi|67010025 Sp4 transcription factor [Homo sapiens]
          Length = 784

 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 99/415 (23%), Positives = 162/415 (39%), Gaps = 57/415 (13%)

Query: 26  PGMEPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAESPSIASTSSTE 85
           PG    T    I+    +  +Q Q   ++LE    +V +QL     G     +AST    
Sbjct: 61  PGENQATGQQQIIIDPSQGLVQLQNQPQQLE----LVTTQLA----GNAWQLVASTPPAS 112

Query: 86  KSFPWRSTDVPNTGVSKPRVSDAVQP---NNYLIRTEPEQGTLYSPEQTSLHESEGSLGN 142
           K             VS+P  S +      N     T+ + G   +P Q  + + +   G+
Sbjct: 113 KE----------NNVSQPASSSSSSSSSNNGSASPTKTKSGNSSTPGQFQVIQVQNPSGS 162

Query: 143 SRSSTQMNSYSDSGYQEAGSFHNSQNVSKADNRQQHSFIGSTNNHVV---RNSRAEGQTL 199
            +        +  G Q     + + + S  D + Q   I + NN  +    N  A G  L
Sbjct: 163 VQYQVIPQLQTVEGQQI--QINPTSSSSLQDLQGQIQLISAGNNQAILTAANRTASGNIL 220

Query: 200 VQPSVANRAM----RRVSSVPSRAQS----PSYVIST------GVS---PSRGSLRTSLG 242
            Q ++AN+ +    R   S+P + Q+     + V++T      GV+   P   ++    G
Sbjct: 221 AQ-NLANQTVPVQIRPGVSIPLQLQTLPGTQAQVVTTLPINIGGVTLALPVINNVAAGGG 279

Query: 243 SG-FGSPSVT-DPRPLNPSAYSSTTLPAARAASPYSQRPASPTAIRRIGS--VTSRQTSN 298
           +G  G P+ T D    N +   ST      +AS   + P+S T      S  +TS  T  
Sbjct: 280 TGQVGQPAATADSGTSNGNQLVSTPTNTTTSASTMPESPSSSTTCTTTASTSLTSSDTLV 339

Query: 299 PNGPTPQYQTTARVGSPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRT- 357
            +  T QY +T+   S  T+ ++QT  A+ S+ Q  SS  + +GM    Q    SLQ+  
Sbjct: 340 SSADTGQYASTSASSSERTIEESQTPAATESEAQ-SSSQLQPNGMQNA-QDQSNSLQQVQ 397

Query: 358 -----VHDMEQFGQQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQDLRSAVSP 407
                +    Q  Q Q  I +  +PP+   L   ++    Q   L      AV+P
Sbjct: 398 IVGQPILQQIQIQQPQQQIIQ-AIPPQSFQLQSGQTIQTIQQQPLQNVQLQAVNP 451


>gi|91206450 ankyrin and armadillo repeat containing [Homo sapiens]
          Length = 1363

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 45/193 (23%), Positives = 81/193 (41%), Gaps = 25/193 (12%)

Query: 528 PELP---EVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVL 584
           PELP    ++ MLQ +    +  A   L+ +C  +++    +   G I  L++LL    +
Sbjct: 626 PELPVWKTLVEMLQCESYKRRMMAVMSLEVICLANDQYWRCILDAGTIPALINLLKSSKI 685

Query: 585 EVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSS 644
           ++Q    G L N+   KS      A+   GGIP+L+ LL    + EV      +L++++ 
Sbjct: 686 KLQCKTVGLLSNISTHKSAVH---ALVEAGGIPSLINLL-VCDEPEVHSRCAVILYDIAQ 741

Query: 645 CDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAG 704
           C+   +    + + +L N                   +      VL N   C+R L    
Sbjct: 742 CENKDVIAKYNGIPSLINL------------------LNLNIENVLVNVMNCIRVLCIGN 783

Query: 705 EEARKQMRSCEGL 717
           E  ++ +R  +GL
Sbjct: 784 ENNQRAVREHKGL 796



 Score = 32.3 bits (72), Expect = 2.8
 Identities = 28/104 (26%), Positives = 47/104 (45%), Gaps = 4/104 (3%)

Query: 867 AVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNG 926
           AVR+ KGLP L+  L  D+D + +  + A+  +  D  NKE+    AM   +  L     
Sbjct: 789 AVREHKGLPYLIRFLSSDSDVLKAVSSAAIAEVGRD--NKEIQDAIAMEGAIPPLVALFK 846

Query: 927 PSVLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNITK 970
              +S +   A+  A+  + S N    KA  +    + L+ + K
Sbjct: 847 GKQISVQMKGAM--AVESLASHNALIQKAFLEKSLTKYLLKLLK 888


>gi|189409124 armadillo repeat containing 3 [Homo sapiens]
          Length = 872

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 42/152 (27%), Positives = 72/152 (47%), Gaps = 22/152 (14%)

Query: 829 PYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRV 888
           P L  L +S N    E +A +L NL+  N    A   AA   + G+  L+ LL    D  
Sbjct: 359 PQLIQLLKSDNEEVREAAALALANLTTCN---PANANAAAEAD-GIDPLINLLSSKRDGA 414

Query: 889 VSSVATALRNMA------LDVRNKELIGKYAMRDLVNRLPGGNGPSVLSDETMAAICCAL 942
           +++ AT L NMA      L+++N ++     M  +++ L   N  +V+  +   A+    
Sbjct: 415 IANAATVLTNMAMQEPLRLNIQNHDI-----MHAIISPLRSAN--TVVQSKAALAVTA-- 465

Query: 943 HEVTSKNMENAKALADSGGIEKLVNITKGRGD 974
              T+ ++E    L +SGG+E LV + + + D
Sbjct: 466 ---TACDVEARTELRNSGGLEPLVELLRSKND 494



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 33/122 (27%), Positives = 54/122 (44%), Gaps = 10/122 (8%)

Query: 877 LVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSVLSDETMA 936
           LV LL  +ND    + + A+  M  +  +K+      +  L+  L   N      +E   
Sbjct: 321 LVALLGSENDGTKIAASQAISAMCENSGSKDFFNNQGIPQLIQLLKSDN------EEVRE 374

Query: 937 AICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRD 996
           A   AL  +T+ N  NA A A++ GI+ L+N+   + D +    +  AA VL  +     
Sbjct: 375 AAALALANLTTCNPANANAAAEADGIDPLINLLSSKRDGA----IANAATVLTNMAMQEP 430

Query: 997 LR 998
           LR
Sbjct: 431 LR 432



 Score = 36.6 bits (83), Expect = 0.15
 Identities = 34/139 (24%), Positives = 54/139 (38%), Gaps = 39/139 (28%)

Query: 556 CFGDNKVKMEVCRLGGIKHLVDLLDHRVL-EVQKNACGALRNLVF--------------- 599
           C  D    +++ + GG+K L+   ++  + ++QKNA  A+    +               
Sbjct: 260 CLEDMDTMVQIQQTGGLKKLLSFAENSTIPDIQKNAAKAITKAAYDPENRKLFHEQEVEK 319

Query: 600 ------GKSTDENKIAMK----------------NVGGIPALLRLLRKSIDAEVRELVTG 637
                 G   D  KIA                  N  GIP L++LL KS + EVRE    
Sbjct: 320 CLVALLGSENDGTKIAASQAISAMCENSGSKDFFNNQGIPQLIQLL-KSDNEEVREAAAL 378

Query: 638 VLWNLSSCDAVKMTIIRDA 656
            L NL++C+        +A
Sbjct: 379 ALANLTTCNPANANAAAEA 397


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.127    0.368 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,154,865
Number of Sequences: 37866
Number of extensions: 2308010
Number of successful extensions: 8347
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 289
Number of HSP's that attempted gapping in prelim test: 7476
Number of HSP's gapped (non-prelim): 952
length of query: 1192
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1078
effective length of database: 13,930,794
effective search space: 15017395932
effective search space used: 15017395932
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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