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Search of human proteins with 51896035
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|51896035 G protein-coupled receptor kinase 6 isoform B [Homo
sapiens]
(589 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|51896035 G protein-coupled receptor kinase 6 isoform B [Homo ... 1213 0.0
gi|51896037 G protein-coupled receptor kinase 6 isoform C [Homo ... 1156 0.0
gi|51896039 G protein-coupled receptor kinase 6 isoform A [Homo ... 1154 0.0
gi|4885349 G protein-coupled receptor kinase 5 [Homo sapiens] 848 0.0
gi|51873043 G protein-coupled receptor kinase 4 isoform alpha [H... 783 0.0
gi|51873047 G protein-coupled receptor kinase 4 isoform gamma [H... 756 0.0
gi|51873045 G protein-coupled receptor kinase 4 isoform beta [Ho... 728 0.0
gi|4506529 rhodopsin kinase [Homo sapiens] 521 e-148
gi|21166359 G-protein-coupled receptor kinase 7 [Homo sapiens] 484 e-136
gi|148539879 beta-adrenergic receptor kinase 2 [Homo sapiens] 317 1e-86
gi|148539876 beta-adrenergic receptor kinase 1 [Homo sapiens] 313 4e-85
gi|4502023 AKT2 kinase [Homo sapiens] 214 2e-55
gi|62241015 AKT1 kinase [Homo sapiens] 212 9e-55
gi|62241013 AKT1 kinase [Homo sapiens] 212 9e-55
gi|62241011 AKT1 kinase [Homo sapiens] 212 9e-55
gi|4506067 protein kinase C, alpha [Homo sapiens] 210 3e-54
gi|47157322 protein kinase C, beta isoform 1 [Homo sapiens] 208 1e-53
gi|4885549 AKT3 kinase isoform 1 [Homo sapiens] 206 6e-53
gi|32307163 AKT3 kinase isoform 2 [Homo sapiens] 206 6e-53
gi|20127450 protein kinase C, beta isoform 2 [Homo sapiens] 202 9e-52
gi|55953117 ribosomal protein S6 kinase, 70kDa, polypeptide 2 [H... 199 5e-51
gi|32528297 ribosomal protein S6 kinase, polypeptide 5 isoform b... 196 4e-50
gi|32528295 ribosomal protein S6 kinase, polypeptide 5 isoform a... 196 4e-50
gi|4506737 ribosomal protein S6 kinase, 70kDa, polypeptide 1 [Ho... 196 5e-50
gi|47157325 protein kinase C, delta [Homo sapiens] 195 1e-49
gi|31377782 protein kinase C, delta [Homo sapiens] 195 1e-49
gi|75709228 protein kinase C, zeta isoform 2 [Homo sapiens] 193 4e-49
gi|75709226 protein kinase C, zeta isoform 2 [Homo sapiens] 193 4e-49
gi|52486327 protein kinase C, zeta isoform 1 [Homo sapiens] 193 4e-49
gi|133908623 protein kinase C, iota [Homo sapiens] 192 9e-49
>gi|51896035 G protein-coupled receptor kinase 6 isoform B [Homo
sapiens]
Length = 589
Score = 1213 bits (3138), Expect = 0.0
Identities = 589/589 (100%), Positives = 589/589 (100%)
Query: 1 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ 60
MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ
Sbjct: 1 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ 60
Query: 61 PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE 120
PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE
Sbjct: 61 PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE 120
Query: 121 VPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQP 180
VPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQP
Sbjct: 121 VPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQP 180
Query: 181 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK 240
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK
Sbjct: 181 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK 240
Query: 241 VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE 300
VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE
Sbjct: 241 VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE 300
Query: 301 DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE 360
DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE
Sbjct: 301 DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE 360
Query: 361 RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC 420
RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC
Sbjct: 361 RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC 420
Query: 421 SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI 480
SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI
Sbjct: 421 SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI 480
Query: 481 EQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWK 540
EQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWK
Sbjct: 481 EQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWK 540
Query: 541 GQPPAPPKKGLLQRLFSRQRIAVETAATARKSSPPASSPQPEAPTSSWR 589
GQPPAPPKKGLLQRLFSRQRIAVETAATARKSSPPASSPQPEAPTSSWR
Sbjct: 541 GQPPAPPKKGLLQRLFSRQRIAVETAATARKSSPPASSPQPEAPTSSWR 589
>gi|51896037 G protein-coupled receptor kinase 6 isoform C [Homo
sapiens]
Length = 560
Score = 1156 bits (2991), Expect = 0.0
Identities = 560/560 (100%), Positives = 560/560 (100%)
Query: 1 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ 60
MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ
Sbjct: 1 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ 60
Query: 61 PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE 120
PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE
Sbjct: 61 PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE 120
Query: 121 VPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQP 180
VPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQP
Sbjct: 121 VPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQP 180
Query: 181 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK 240
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK
Sbjct: 181 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK 240
Query: 241 VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE 300
VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE
Sbjct: 241 VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE 300
Query: 301 DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE 360
DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE
Sbjct: 301 DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE 360
Query: 361 RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC 420
RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC
Sbjct: 361 RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC 420
Query: 421 SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI 480
SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI
Sbjct: 421 SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI 480
Query: 481 EQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWK 540
EQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWK
Sbjct: 481 EQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWK 540
Query: 541 GQPPAPPKKGLLQRLFSRQR 560
GQPPAPPKKGLLQRLFSRQR
Sbjct: 541 GQPPAPPKKGLLQRLFSRQR 560
>gi|51896039 G protein-coupled receptor kinase 6 isoform A [Homo
sapiens]
Length = 576
Score = 1154 bits (2986), Expect = 0.0
Identities = 559/559 (100%), Positives = 559/559 (100%)
Query: 1 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ 60
MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ
Sbjct: 1 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ 60
Query: 61 PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE 120
PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE
Sbjct: 61 PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE 120
Query: 121 VPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQP 180
VPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQP
Sbjct: 121 VPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQP 180
Query: 181 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK 240
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK
Sbjct: 181 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK 240
Query: 241 VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE 300
VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE
Sbjct: 241 VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE 300
Query: 301 DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE 360
DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE
Sbjct: 301 DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE 360
Query: 361 RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC 420
RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC
Sbjct: 361 RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC 420
Query: 421 SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI 480
SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI
Sbjct: 421 SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI 480
Query: 481 EQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWK 540
EQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWK
Sbjct: 481 EQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWK 540
Query: 541 GQPPAPPKKGLLQRLFSRQ 559
GQPPAPPKKGLLQRLFSRQ
Sbjct: 541 GQPPAPPKKGLLQRLFSRQ 559
>gi|4885349 G protein-coupled receptor kinase 5 [Homo sapiens]
Length = 590
Score = 848 bits (2190), Expect = 0.0
Identities = 406/573 (70%), Positives = 477/573 (83%), Gaps = 1/573 (0%)
Query: 1 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ 60
MELENIVANTVLLKAREGGGG RKGKSKKW+++L+FPHISQCE+LR +++RDY SLC++Q
Sbjct: 1 MELENIVANTVLLKAREGGGGKRKGKSKKWKEILKFPHISQCEDLRRTIDRDYCSLCDKQ 60
Query: 61 PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE 120
PIGRLLFR+FC TRP L + FLD VAEYEVTPD+K G+++ +L+ P I +
Sbjct: 61 PIGRLLFRQFCETRPGLECYIQFLDSVAEYEVTPDEKLGEKGKEIMTKYLTPKSPVFIAQ 120
Query: 121 VPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQP 180
V + LV+ ++L Q PCK+LF + HEYL PF +YLDS++F+RFLQWKWLERQP
Sbjct: 121 VGQDLVSQTEEKLLQKPCKELFSACAQSVHEYLRGEPFHEYLDSMFFDRFLQWKWLERQP 180
Query: 181 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK 240
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACK+LEKKRIKKRKGE+MALNEKQILEK
Sbjct: 181 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEK 240
Query: 241 VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE 300
VNS+FVV+LAYAYETKDALCLVLT+MNGGDLKFHIY+MG GF E RA+FYAAEI CGLE
Sbjct: 241 VNSQFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLE 300
Query: 301 DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE 360
DLHRE VYRDLKPENILLDD+GHIRISDLGLAV +PEG I+GRVGTVGYMAPEV+ N+
Sbjct: 301 DLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQ 360
Query: 361 RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC 420
RY SPD+W LGCL+YEMI GQSPF+ RK+K+KREEV+R V E E YS +FS +A+S+C
Sbjct: 361 RYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSIC 420
Query: 421 SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI 480
LL KD +RLGC+ A EVK HP F+ +NFKRL AGML+PPF PDP+A+YCKDVLDI
Sbjct: 421 KMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYCKDVLDI 480
Query: 481 EQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWK 540
EQFSTVKGV L+ TD DFY KF+TGSV IPWQNEM+ETECF+ELNVFG +G++PPDL+ +
Sbjct: 481 EQFSTVKGVNLDHTDDDFYSKFSTGSVSIPWQNEMIETECFKELNVFGPNGTLPPDLN-R 539
Query: 541 GQPPAPPKKGLLQRLFSRQRIAVETAATARKSS 573
PP PPKKGLLQRLF RQ ++ + K+S
Sbjct: 540 NHPPEPPKKGLLQRLFKRQHQNNSKSSPSSKTS 572
>gi|51873043 G protein-coupled receptor kinase 4 isoform alpha [Homo
sapiens]
Length = 578
Score = 783 bits (2022), Expect = 0.0
Identities = 374/560 (66%), Positives = 446/560 (79%), Gaps = 2/560 (0%)
Query: 1 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ 60
MELENIVAN++LLKAR+GG G + G+SKKW+++L P +SQC ELR S+E+DY SLC++Q
Sbjct: 1 MELENIVANSLLLKARQGGYGKKSGRSKKWKEILTLPPVSQCSELRHSIEKDYSSLCDKQ 60
Query: 61 PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE 120
PIGR LFR+FC T+P L R + FLD VAEYEV D+ R CG + F + +PE
Sbjct: 61 PIGRRLFRQFCDTKPTLKRHIEFLDAVAEYEVADDEDRSDCGLSILDRFFNDKLAAPLPE 120
Query: 121 VPRQLVTNCTQRL-EQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQ 179
+P +VT C L E+ P K F+E TR+ H YL PF +Y +S YF++FLQWKWLERQ
Sbjct: 121 IPPDVVTECRLGLKEENPSKKAFEECTRVAHNYLRGEPFEEYQESSYFSQFLQWKWLERQ 180
Query: 180 PVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILE 239
PVTKNTFR YRVLGKGGFGEVCACQVRATGKMYACKKL+KKRIKKRKGEAMALNEK+ILE
Sbjct: 181 PVTKNTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALNEKRILE 240
Query: 240 KVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGL 299
KV SRFVVSLAYAYETKDALCLVLT+MNGGDLKFHIY++G GF E RAVFYAAE+CCGL
Sbjct: 241 KVQSRFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGL 300
Query: 300 EDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKN 359
EDL RERIVYRDLKPENILLDD GHIRISDLGLA +PEGQ ++GRVGTVGYMAPEVV N
Sbjct: 301 EDLQRERIVYRDLKPENILLDDRGHIRISDLGLATEIPEGQRVRGRVGTVGYMAPEVVNN 360
Query: 360 ERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSL 419
E+YTFSPDWW LGCL+YEMI G SPF++ K+K+K EEV++ +K EEYSE+FS A+S+
Sbjct: 361 EKYTFSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSI 420
Query: 420 CSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLD 479
C LL K+P++RLGCRG A VK+HP+FK +NF+RL A MLEPPF PDP A+YCKDVLD
Sbjct: 421 CRMLLTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCPDPHAVYCKDVLD 480
Query: 480 IEQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDW 539
IEQFS VKG+ L+ D+DFY +FATG V IPWQNEM+E+ CF+++N + ++P DLD
Sbjct: 481 IEQFSVVKGIYLDTADEDFYARFATGCVSIPWQNEMIESGCFKDINKSESEEALPLDLDK 540
Query: 540 K-GQPPAPPKKGLLQRLFSR 558
P + P +G RLF R
Sbjct: 541 NIHTPVSRPNRGFFYRLFRR 560
>gi|51873047 G protein-coupled receptor kinase 4 isoform gamma [Homo
sapiens]
Length = 532
Score = 756 bits (1951), Expect = 0.0
Identities = 358/515 (69%), Positives = 420/515 (81%), Gaps = 1/515 (0%)
Query: 1 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ 60
MELENIVAN++LLKAR+GG G + G+SKKW+++L P +SQC ELR S+E+DY SLC++Q
Sbjct: 1 MELENIVANSLLLKARQGGYGKKSGRSKKWKEILTLPPVSQCSELRHSIEKDYSSLCDKQ 60
Query: 61 PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE 120
PIGR LFR+FC T+P L R + FLD VAEYEV D+ R CG + F + +PE
Sbjct: 61 PIGRRLFRQFCDTKPTLKRHIEFLDAVAEYEVADDEDRSDCGLSILDRFFNDKLAAPLPE 120
Query: 121 VPRQLVTNCTQRL-EQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQ 179
+P +VT C L E+ P K F+E TR+ H YL PF +Y +S YF++FLQWKWLERQ
Sbjct: 121 IPPDVVTECRLGLKEENPSKKAFEECTRVAHNYLRGEPFEEYQESSYFSQFLQWKWLERQ 180
Query: 180 PVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILE 239
PVTKNTFR YRVLGKGGFGEVCACQVRATGKMYACKKL+KKRIKKRKGEAMALNEK+ILE
Sbjct: 181 PVTKNTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALNEKRILE 240
Query: 240 KVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGL 299
KV SRFVVSLAYAYETKDALCLVLT+MNGGDLKFHIY++G GF E RAVFYAAE+CCGL
Sbjct: 241 KVQSRFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGL 300
Query: 300 EDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKN 359
EDL RERIVYRDLKPENILLDD GHIRISDLGLA +PEGQ ++GRVGTVGYMAPEVV N
Sbjct: 301 EDLQRERIVYRDLKPENILLDDRGHIRISDLGLATEIPEGQRVRGRVGTVGYMAPEVVNN 360
Query: 360 ERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSL 419
E+YTFSPDWW LGCL+YEMI G SPF++ K+K+K EEV++ +K EEYSE+FS A+S+
Sbjct: 361 EKYTFSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSI 420
Query: 420 CSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLD 479
C LL K+P++RLGCRG A VK+HP+FK +NF+RL A MLEPPF PDP A+YCKDVLD
Sbjct: 421 CRMLLTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCPDPHAVYCKDVLD 480
Query: 480 IEQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNE 514
IEQFS VKG+ L+ D+DFY +FATG V IPWQNE
Sbjct: 481 IEQFSVVKGIYLDTADEDFYARFATGCVSIPWQNE 515
>gi|51873045 G protein-coupled receptor kinase 4 isoform beta [Homo
sapiens]
Length = 546
Score = 728 bits (1878), Expect = 0.0
Identities = 357/560 (63%), Positives = 422/560 (75%), Gaps = 34/560 (6%)
Query: 1 MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ 60
MELENIVAN++LLKAR+ E+DY SLC++Q
Sbjct: 1 MELENIVANSLLLKARQ--------------------------------EKDYSSLCDKQ 28
Query: 61 PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE 120
PIGR LFR+FC T+P L R + FLD VAEYEV D+ R CG + F + +PE
Sbjct: 29 PIGRRLFRQFCDTKPTLKRHIEFLDAVAEYEVADDEDRSDCGLSILDRFFNDKLAAPLPE 88
Query: 121 VPRQLVTNCTQRL-EQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQ 179
+P +VT C L E+ P K F+E TR+ H YL PF +Y +S YF++FLQWKWLERQ
Sbjct: 89 IPPDVVTECRLGLKEENPSKKAFEECTRVAHNYLRGEPFEEYQESSYFSQFLQWKWLERQ 148
Query: 180 PVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILE 239
PVTKNTFR YRVLGKGGFGEVCACQVRATGKMYACKKL+KKRIKKRKGEAMALNEK+ILE
Sbjct: 149 PVTKNTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALNEKRILE 208
Query: 240 KVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGL 299
KV SRFVVSLAYAYETKDALCLVLT+MNGGDLKFHIY++G GF E RAVFYAAE+CCGL
Sbjct: 209 KVQSRFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGL 268
Query: 300 EDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKN 359
EDL RERIVYRDLKPENILLDD GHIRISDLGLA +PEGQ ++GRVGTVGYMAPEVV N
Sbjct: 269 EDLQRERIVYRDLKPENILLDDRGHIRISDLGLATEIPEGQRVRGRVGTVGYMAPEVVNN 328
Query: 360 ERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSL 419
E+YTFSPDWW LGCL+YEMI G SPF++ K+K+K EEV++ +K EEYSE+FS A+S+
Sbjct: 329 EKYTFSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSI 388
Query: 420 CSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLD 479
C LL K+P++RLGCRG A VK+HP+FK +NF+RL A MLEPPF PDP A+YCKDVLD
Sbjct: 389 CRMLLTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCPDPHAVYCKDVLD 448
Query: 480 IEQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDW 539
IEQFS VKG+ L+ D+DFY +FATG V IPWQNEM+E+ CF+++N + ++P DLD
Sbjct: 449 IEQFSVVKGIYLDTADEDFYARFATGCVSIPWQNEMIESGCFKDINKSESEEALPLDLDK 508
Query: 540 K-GQPPAPPKKGLLQRLFSR 558
P + P +G RLF R
Sbjct: 509 NIHTPVSRPNRGFFYRLFRR 528
>gi|4506529 rhodopsin kinase [Homo sapiens]
Length = 563
Score = 521 bits (1341), Expect = e-148
Identities = 262/543 (48%), Positives = 371/543 (68%), Gaps = 12/543 (2%)
Query: 3 LENIVANTVLLKAREG--GGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ 60
LE +VAN+ + AR G ++ + KK+ L+ P +S+CE LR SL ++ S+C Q
Sbjct: 6 LETVVANSAFIAARGSFDGSSSQPSRDKKYLAKLKLPPLSKCESLRDSLSLEFESVCLEQ 65
Query: 61 PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE 120
PIG+ LF++F + + + + +Y+ +D + + + +L
Sbjct: 66 PIGKKLFQQFLQSAEKHLPALELWKDIEDYDTADNDLQPQKAQTILAQYLDPQAKLFCSF 125
Query: 121 VPRQLVTNCTQRLEQGPCK---DLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLE 177
+ +V + ++GP + LFQ L + T +L APF +YL S+YF RFLQWKWLE
Sbjct: 126 LDEGIVA----KFKEGPVEIQDGLFQPLLQATLAHLGQAPFQEYLGSLYFLRFLQWKWLE 181
Query: 178 RQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQI 237
QP+ ++ F +RVLGKGGFGEV ACQ++ATGK+YACKKL KKR+KKRKG A+ EK+I
Sbjct: 182 AQPMGEDWFLDFRVLGKGGFGEVSACQMKATGKLYACKKLNKKRLKKRKGYQGAMVEKKI 241
Query: 238 LEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQA--GFPEARAVFYAAEI 295
L KV+SRF+VSLAYA+ETK LCLV+T+MNGGD+++HIY++ + GFPE RA+FY A+I
Sbjct: 242 LMKVHSRFIVSLAYAFETKADLCLVMTIMNGGDIRYHIYNVNEENPGFPEPRALFYTAQI 301
Query: 296 CCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQT-IKGRVGTVGYMAP 354
CGLE LH+ RIVYRDLKPEN+LLD+ G++RISDLGLAV + +GQ+ KG GT G+MAP
Sbjct: 302 ICGLEHLHQRRIVYRDLKPENVLLDNDGNVRISDLGLAVELLDGQSKTKGYAGTPGFMAP 361
Query: 355 EVVKNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSP 414
E+++ E Y FS D++ALG LYEMIA + PF+ R +K++ +E++ + P +Y ++FS
Sbjct: 362 ELLQGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKHRIISEPVKYPDKFSQ 421
Query: 415 QARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYC 474
++ C LL KDP +RLG R + +++ HPLFK LN+++L AGML PPF PD + +Y
Sbjct: 422 ASKDFCEALLEKDPEKRLGFRDETCDKLRAHPLFKDLNWRQLEAGMLMPPFIPDSKTVYA 481
Query: 475 KDVLDIEQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVP 534
KD+ D+ FSTVKGV + TD +F+Q+FATG+ PIPWQ EM+ET F ELNV+ DG +P
Sbjct: 482 KDIQDVGAFSTVKGVAFDKTDTEFFQEFATGNCPIPWQEEMIETGIFGELNVWRSDGQMP 541
Query: 535 PDL 537
D+
Sbjct: 542 DDM 544
>gi|21166359 G-protein-coupled receptor kinase 7 [Homo sapiens]
Length = 553
Score = 484 bits (1245), Expect = e-136
Identities = 245/527 (46%), Positives = 350/527 (66%), Gaps = 6/527 (1%)
Query: 3 LENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQPI 62
L+N++ANT L+AR+ + K ++ R+ L P + C ELR L ++HSLCE+QPI
Sbjct: 7 LDNLIANTAYLQARKPSDCDSKELQRR-RRSLALPGLQGCAELRQKLSLNFHSLCEQQPI 65
Query: 63 GRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQ-LTQNFLSHTGP-DLIPE 120
GR LFR+F AT P + FL+ V +E+ + K Q L S P + P
Sbjct: 66 GRRLFRDFLATVPTFRKAATFLEDVQNWELAEEGPTKDSALQGLVATCASAPAPGNPQPF 125
Query: 121 VPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQP 180
+ + + T C + +L PF D++ S ++++FLQWK E QP
Sbjct: 126 LSQAVATKCQAATTEEERVAAVTLAKAEAMAFLQEQPFKDFVTSAFYDKFLQWKLFEMQP 185
Query: 181 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK 240
V+ F ++RVLGKGGFGEVCA QV+ TGKMYACKKL+KKR+KK+ GE MAL EK+ILEK
Sbjct: 186 VSDKYFTEFRVLGKGGFGEVCAVQVKNTGKMYACKKLDKKRLKKKGGEKMALLEKEILEK 245
Query: 241 VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE 300
V+S F+VSLAYA+E+K LCLV++LMNGGDLKFHIY++G G +R +FY+A+I CG+
Sbjct: 246 VSSPFIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRGLDMSRVIFYSAQIACGML 305
Query: 301 DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE 360
LH IVYRD+KPEN+LLDD G+ R+SDLGLAV + G+ I R GT GYMAPE++ +
Sbjct: 306 HLHELGIVYRDMKPENVLLDDLGNCRLSDLGLAVEMKGGKPITQRAGTNGYMAPEILMEK 365
Query: 361 -RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEV-ERLVKEVPEEYSERFSPQARS 418
Y++ DW+A+GC +YEM+AG++PF+ K+K+ +E++ +R +++ + + F+ +A+
Sbjct: 366 VSYSYPVDWFAMGCSIYEMVAGRTPFKDYKEKVSKEDLKQRTLQDEVKFQHDNFTEEAKD 425
Query: 419 LCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVL 478
+C L K P +RLG R S + ++H FK +NF RL AG++EPPF PDP +Y KD+
Sbjct: 426 ICRLFLAKKPEQRLGSREKS-DDPRKHHFFKTINFPRLEAGLIEPPFVPDPSVVYAKDIA 484
Query: 479 DIEQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELN 525
+I+ FS V+GVE + D+ F++ FATG+VPI WQ E++ET F+ELN
Sbjct: 485 EIDDFSEVRGVEFDDKDKQFFKNFATGAVPIAWQEEIIETGLFEELN 531
>gi|148539879 beta-adrenergic receptor kinase 2 [Homo sapiens]
Length = 688
Score = 317 bits (813), Expect = 1e-86
Identities = 204/529 (38%), Positives = 291/529 (55%), Gaps = 19/529 (3%)
Query: 2 ELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCE--R 59
+LE ++A+ L A E ++ K R +L P I + L+ ER+ + +
Sbjct: 3 DLEAVLADVSYLMAMEKSKATPAARASK-RIVLPEPSIRSVMQKYLA-ERNEITFDKIFN 60
Query: 60 QPIGRLLFREFCATR-PELSRCVAFLDGVAEYEVTPDDKRKAC-GRQLTQNFLSHTGPDL 117
Q IG LLF++FC E V F + + EYE +++ + C RQ+ ++
Sbjct: 61 QKIGFLLFKDFCLNEINEAVPQVKFYEEIKEYEKLDNEEDRLCRSRQIYDAYIMKELLSC 120
Query: 118 IPEVPRQLVTNCTQRLEQGPCKD-LFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWL 176
+Q V + L + LFQ E L F +++S F RF QWK +
Sbjct: 121 SHPFSKQAVEHVQSHLSKKQVTSTLFQPYIEEICESLRGDIFQKFMESDKFTRFCQWKNV 180
Query: 177 ERQ-PVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEK 235
E +T N F +R++G+GGFGEV C+ TGKMYA K L+KKRIK ++GE +ALNE+
Sbjct: 181 ELNIHLTMNEFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER 240
Query: 236 QILEKVNS---RFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYA 292
+L V++ F+V + YA+ T D LC +L LMNGGDL +H+ G F E FYA
Sbjct: 241 IMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDLHYHLSQHGV--FSEKEMRFYA 298
Query: 293 AEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYM 352
EI GLE +H +VYRDLKP NILLD+HGH RISDLGLA + + VGT GYM
Sbjct: 299 TEIILGLEHMHNRFVVYRDLKPANILLDEHGHARISDLGLACDFSKKKP-HASVGTHGYM 357
Query: 353 APEVV-KNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSER 411
APEV+ K Y S DW++LGC+L++++ G SPF+Q K K K E++R+ V E +
Sbjct: 358 APEVLQKGTAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDK-HEIDRMTLTVNVELPDT 416
Query: 412 FSPQARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQA 471
FSP+ +SL LL +D ++RLGC GG ++EVKEH FK ++++ + PP P
Sbjct: 417 FSPELKSLLEGLLQRDVSKRLGCHGGGSQEVKEHSFFKGVDWQHVYLQKYPPPLIPPRGE 476
Query: 472 IYCKDVLDIEQF--STVKGVELEPTDQDFYQKFATGSVPIPWQNEMVET 518
+ D DI F KG++L DQ+ Y+ F + WQ E+ ET
Sbjct: 477 VNAADAFDIGSFDEEDTKGIKLLDCDQELYKNFPL-VISERWQQEVTET 524
>gi|148539876 beta-adrenergic receptor kinase 1 [Homo sapiens]
Length = 689
Score = 313 bits (801), Expect = 4e-85
Identities = 203/531 (38%), Positives = 294/531 (55%), Gaps = 23/531 (4%)
Query: 2 ELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCER-- 59
+LE ++A+ L A E ++ K + P S ++ LE E+
Sbjct: 3 DLEAVLADVSYLMAMEKSKATPAARASK---KILLPEPSIRSVMQKYLEDRGEVTFEKIF 59
Query: 60 -QPIGRLLFREFCATRPELSR-CVAFLDGVAEYE-VTPDDKRKACGRQLTQNFLSHTGPD 116
Q +G LLFR+FC E +R V F + + +YE + +++R A R++ +++
Sbjct: 60 SQKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLA 119
Query: 117 LIPEVPRQLVTNCTQRL--EQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWK 174
+ + L +Q P DLFQ + L F +++S F RF QWK
Sbjct: 120 CSHPFSKSATEHVQGHLGKKQVP-PDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWK 178
Query: 175 WLERQ-PVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALN 233
+E +T N F +R++G+GGFGEV C+ TGKMYA K L+KKRIK ++GE +ALN
Sbjct: 179 NVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALN 238
Query: 234 EKQILEKVNSR---FVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVF 290
E+ +L V++ F+V ++YA+ T D L +L LMNGGDL +H+ G F EA F
Sbjct: 239 ERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGV--FSEADMRF 296
Query: 291 YAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVG 350
YAAEI GLE +H +VYRDLKP NILLD+HGH+RISDLGLA + + VGT G
Sbjct: 297 YAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKP-HASVGTHG 355
Query: 351 YMAPEVV-KNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYS 409
YMAPEV+ K Y S DW++LGC+L++++ G SPF+Q K K K E++R+ + E
Sbjct: 356 YMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDK-HEIDRMTLTMAVELP 414
Query: 410 ERFSPQARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDP 469
+ FSP+ RSL LL +D RLGC G A+EVKE P F+ L+++ + PP P
Sbjct: 415 DSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPR 474
Query: 470 QAIYCKDVLDIEQF--STVKGVELEPTDQDFYQKFATGSVPIPWQNEMVET 518
+ D DI F KG++L +DQ+ Y+ F ++ WQ E+ ET
Sbjct: 475 GEVNAADAFDIGSFDEEDTKGIKLLDSDQELYRNFPL-TISERWQQEVAET 524
>gi|4502023 AKT2 kinase [Homo sapiens]
Length = 481
Score = 214 bits (544), Expect = 2e-55
Identities = 123/320 (38%), Positives = 179/320 (55%), Gaps = 9/320 (2%)
Query: 178 RQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQI 237
R VT N F ++LGKG FG+V + +ATG+ YA K L K+ I + A + E ++
Sbjct: 144 RAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRV 203
Query: 238 LEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICC 297
L+ F+ +L YA++T D LC V+ NGG+L FH+ + F E RA FY AEI
Sbjct: 204 LQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSR--ERVFTEERARFYGAEIVS 261
Query: 298 GLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVH-VPEGQTIKGRVGTVGYMAPEV 356
LE LH +VYRD+K EN++LD GHI+I+D GL + +G T+K GT Y+APEV
Sbjct: 262 ALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEV 321
Query: 357 VKNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQA 416
+++ Y + DWW LG ++YEM+ G+ PF + E + L+ + SP+A
Sbjct: 322 LEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQ----DHERLFELILMEEIRFPRTLSPEA 377
Query: 417 RSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKD 476
+SL + LL KDP +RLG A+EV EH F +N++ + L PPFK PQ D
Sbjct: 378 KSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFK--PQVTSEVD 435
Query: 477 VLDIEQFSTVKGVELEPTDQ 496
+ T + + + P D+
Sbjct: 436 TRYFDDEFTAQSITITPPDR 455
>gi|62241015 AKT1 kinase [Homo sapiens]
Length = 480
Score = 212 bits (539), Expect = 9e-55
Identities = 122/319 (38%), Positives = 182/319 (57%), Gaps = 10/319 (3%)
Query: 181 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK 240
VT N F ++LGKG FG+V + +ATG+ YA K L+K+ I + A L E ++L+
Sbjct: 145 VTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQN 204
Query: 241 VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE 300
F+ +L Y+++T D LC V+ NGG+L FH+ + F E RA FY AEI L+
Sbjct: 205 SRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR--ERVFSEDRARFYGAEIVSALD 262
Query: 301 DLHRER-IVYRDLKPENILLDDHGHIRISDLGLAVH-VPEGQTIKGRVGTVGYMAPEVVK 358
LH E+ +VYRDLK EN++LD GHI+I+D GL + +G T+K GT Y+APEV++
Sbjct: 263 YLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLE 322
Query: 359 NERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARS 418
+ Y + DWW LG ++YEM+ G+ PF + E++ L+ + P+A+S
Sbjct: 323 DNDYGRAVDWWGLGVVMYEMMCGRLPFYNQ----DHEKLFELILMEEIRFPRTLGPEAKS 378
Query: 419 LCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVL 478
L S LL KDP +RLG A+E+ +H F + ++ + L PPFK PQ D
Sbjct: 379 LLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFK--PQVTSETDTR 436
Query: 479 DIEQFSTVKGVELEPTDQD 497
++ T + + + P DQD
Sbjct: 437 YFDEEFTAQMITITPPDQD 455
>gi|62241013 AKT1 kinase [Homo sapiens]
Length = 480
Score = 212 bits (539), Expect = 9e-55
Identities = 122/319 (38%), Positives = 182/319 (57%), Gaps = 10/319 (3%)
Query: 181 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK 240
VT N F ++LGKG FG+V + +ATG+ YA K L+K+ I + A L E ++L+
Sbjct: 145 VTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQN 204
Query: 241 VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE 300
F+ +L Y+++T D LC V+ NGG+L FH+ + F E RA FY AEI L+
Sbjct: 205 SRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR--ERVFSEDRARFYGAEIVSALD 262
Query: 301 DLHRER-IVYRDLKPENILLDDHGHIRISDLGLAVH-VPEGQTIKGRVGTVGYMAPEVVK 358
LH E+ +VYRDLK EN++LD GHI+I+D GL + +G T+K GT Y+APEV++
Sbjct: 263 YLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLE 322
Query: 359 NERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARS 418
+ Y + DWW LG ++YEM+ G+ PF + E++ L+ + P+A+S
Sbjct: 323 DNDYGRAVDWWGLGVVMYEMMCGRLPFYNQ----DHEKLFELILMEEIRFPRTLGPEAKS 378
Query: 419 LCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVL 478
L S LL KDP +RLG A+E+ +H F + ++ + L PPFK PQ D
Sbjct: 379 LLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFK--PQVTSETDTR 436
Query: 479 DIEQFSTVKGVELEPTDQD 497
++ T + + + P DQD
Sbjct: 437 YFDEEFTAQMITITPPDQD 455
>gi|62241011 AKT1 kinase [Homo sapiens]
Length = 480
Score = 212 bits (539), Expect = 9e-55
Identities = 122/319 (38%), Positives = 182/319 (57%), Gaps = 10/319 (3%)
Query: 181 VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK 240
VT N F ++LGKG FG+V + +ATG+ YA K L+K+ I + A L E ++L+
Sbjct: 145 VTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQN 204
Query: 241 VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE 300
F+ +L Y+++T D LC V+ NGG+L FH+ + F E RA FY AEI L+
Sbjct: 205 SRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSR--ERVFSEDRARFYGAEIVSALD 262
Query: 301 DLHRER-IVYRDLKPENILLDDHGHIRISDLGLAVH-VPEGQTIKGRVGTVGYMAPEVVK 358
LH E+ +VYRDLK EN++LD GHI+I+D GL + +G T+K GT Y+APEV++
Sbjct: 263 YLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLE 322
Query: 359 NERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARS 418
+ Y + DWW LG ++YEM+ G+ PF + E++ L+ + P+A+S
Sbjct: 323 DNDYGRAVDWWGLGVVMYEMMCGRLPFYNQ----DHEKLFELILMEEIRFPRTLGPEAKS 378
Query: 419 LCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVL 478
L S LL KDP +RLG A+E+ +H F + ++ + L PPFK PQ D
Sbjct: 379 LLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFK--PQVTSETDTR 436
Query: 479 DIEQFSTVKGVELEPTDQD 497
++ T + + + P DQD
Sbjct: 437 YFDEEFTAQMITITPPDQD 455
>gi|4506067 protein kinase C, alpha [Homo sapiens]
Length = 672
Score = 210 bits (535), Expect = 3e-54
Identities = 120/313 (38%), Positives = 182/313 (58%), Gaps = 11/313 (3%)
Query: 186 FRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSR- 244
F VLGKG FG+V + T ++YA K L+K + + + EK++L ++
Sbjct: 339 FNFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPP 398
Query: 245 FVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHR 304
F+ L ++T D L V+ +NGGDL +HI +G+ F E +AVFYAAEI GL LH+
Sbjct: 399 FLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQQVGK--FKEPQAVFYAAEISIGLFFLHK 456
Query: 305 ERIVYRDLKPENILLDDHGHIRISDLGLA-VHVPEGQTIKGRVGTVGYMAPEVVKNERYT 363
I+YRDLK +N++LD GHI+I+D G+ H+ +G T + GT Y+APE++ + Y
Sbjct: 457 RGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYG 516
Query: 364 FSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLCSQL 423
S DWWA G LLYEM+AGQ PF + +E+ + + E Y + S +A S+C L
Sbjct: 517 KSVDWWAYGVLLYEMLAGQPPFDGEDE----DELFQSIMEHNVSYPKSLSKEAVSICKGL 572
Query: 424 LCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQF 483
+ K PA+RLGC R+V+EH F+++++++L ++PPFKP + K + ++F
Sbjct: 573 MTKHPAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKP---KVCGKGAENFDKF 629
Query: 484 STVKGVELEPTDQ 496
T L P DQ
Sbjct: 630 FTRGQPVLTPPDQ 642
>gi|47157322 protein kinase C, beta isoform 1 [Homo sapiens]
Length = 671
Score = 208 bits (529), Expect = 1e-53
Identities = 119/315 (37%), Positives = 185/315 (58%), Gaps = 10/315 (3%)
Query: 186 FRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSR- 244
F VLGKG FG+V + + T ++YA K L+K + + + EK++L
Sbjct: 342 FNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPP 401
Query: 245 FVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHR 304
F+ L ++T D L V+ +NGGDL +HI +G+ F E AVFYAAEI GL L
Sbjct: 402 FLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGR--FKEPHAVFYAAEIAIGLFFLQS 459
Query: 305 ERIVYRDLKPENILLDDHGHIRISDLGLA-VHVPEGQTIKGRVGTVGYMAPEVVKNERYT 363
+ I+YRDLK +N++LD GHI+I+D G+ ++ +G T K GT Y+APE++ + Y
Sbjct: 460 KGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYG 519
Query: 364 FSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLCSQL 423
S DWWA G LLYEM+AGQ+PF+ + +E+ + + E Y + S +A ++C L
Sbjct: 520 KSVDWWAFGVLLYEMLAGQAPFEGEDE----DELFQSIMEHNVAYPKSMSKEAVAICKGL 575
Query: 424 LCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQF 483
+ K P +RLGC R++KEH F+ +++++L ++PP+K P+A +D + ++
Sbjct: 576 MTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYK--PKARDKRDTSNFDKE 633
Query: 484 STVKGVELEPTDQDF 498
T + VEL PTD+ F
Sbjct: 634 FTRQPVELTPTDKLF 648
>gi|4885549 AKT3 kinase isoform 1 [Homo sapiens]
Length = 479
Score = 206 bits (523), Expect = 6e-53
Identities = 115/287 (40%), Positives = 168/287 (58%), Gaps = 7/287 (2%)
Query: 182 TKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKV 241
T N F ++LGKG FG+V + +A+GK YA K L+K+ I + A L E ++L+
Sbjct: 144 TMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNT 203
Query: 242 NSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLED 301
F+ SL Y+++TKD LC V+ +NGG+L FH+ + F E R FY AEI L+
Sbjct: 204 RHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSR--ERVFSEDRTRFYGAEIVSALDY 261
Query: 302 LHRERIVYRDLKPENILLDDHGHIRISDLGLAVH-VPEGQTIKGRVGTVGYMAPEVVKNE 360
LH +IVYRDLK EN++LD GHI+I+D GL + + T+K GT Y+APEV+++
Sbjct: 262 LHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDN 321
Query: 361 RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC 420
Y + DWW LG ++YEM+ G+ PF + E++ L+ ++ S A+SL
Sbjct: 322 DYGRAVDWWGLGVVMYEMMCGRLPFYNQ----DHEKLFELILMEDIKFPRTLSSDAKSLL 377
Query: 421 SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKP 467
S LL KDP +RLG A+E+ H F +N++ + L PPFKP
Sbjct: 378 SGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKP 424
>gi|32307163 AKT3 kinase isoform 2 [Homo sapiens]
Length = 465
Score = 206 bits (523), Expect = 6e-53
Identities = 115/287 (40%), Positives = 168/287 (58%), Gaps = 7/287 (2%)
Query: 182 TKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKV 241
T N F ++LGKG FG+V + +A+GK YA K L+K+ I + A L E ++L+
Sbjct: 144 TMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNT 203
Query: 242 NSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLED 301
F+ SL Y+++TKD LC V+ +NGG+L FH+ + F E R FY AEI L+
Sbjct: 204 RHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSR--ERVFSEDRTRFYGAEIVSALDY 261
Query: 302 LHRERIVYRDLKPENILLDDHGHIRISDLGLAVH-VPEGQTIKGRVGTVGYMAPEVVKNE 360
LH +IVYRDLK EN++LD GHI+I+D GL + + T+K GT Y+APEV+++
Sbjct: 262 LHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDN 321
Query: 361 RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC 420
Y + DWW LG ++YEM+ G+ PF + E++ L+ ++ S A+SL
Sbjct: 322 DYGRAVDWWGLGVVMYEMMCGRLPFYNQ----DHEKLFELILMEDIKFPRTLSSDAKSLL 377
Query: 421 SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKP 467
S LL KDP +RLG A+E+ H F +N++ + L PPFKP
Sbjct: 378 SGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKP 424
>gi|20127450 protein kinase C, beta isoform 2 [Homo sapiens]
Length = 673
Score = 202 bits (513), Expect = 9e-52
Identities = 115/314 (36%), Positives = 180/314 (57%), Gaps = 11/314 (3%)
Query: 186 FRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSR- 244
F VLGKG FG+V + + T ++YA K L+K + + + EK++L
Sbjct: 342 FNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPP 401
Query: 245 FVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHR 304
F+ L ++T D L V+ +NGGDL +HI +G+ F E AVFYAAEI GL L
Sbjct: 402 FLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGR--FKEPHAVFYAAEIAIGLFFLQS 459
Query: 305 ERIVYRDLKPENILLDDHGHIRISDLGLA-VHVPEGQTIKGRVGTVGYMAPEVVKNERYT 363
+ I+YRDLK +N++LD GHI+I+D G+ ++ +G T K GT Y+APE++ + Y
Sbjct: 460 KGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYG 519
Query: 364 FSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLCSQL 423
S DWWA G LLYEM+AGQ+PF+ + +E+ + + E Y + S +A ++C L
Sbjct: 520 KSVDWWAFGVLLYEMLAGQAPFEGEDE----DELFQSIMEHNVAYPKSMSKEAVAICKGL 575
Query: 424 LCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQF 483
+ K P +RLGC R++KEH F+ +++++L ++PP+KP ++ + ++F
Sbjct: 576 MTKHPGKRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKACG---RNAENFDRF 632
Query: 484 STVKGVELEPTDQD 497
T L P DQ+
Sbjct: 633 FTRHPPVLTPPDQE 646
>gi|55953117 ribosomal protein S6 kinase, 70kDa, polypeptide 2 [Homo
sapiens]
Length = 482
Score = 199 bits (507), Expect = 5e-51
Identities = 119/305 (39%), Positives = 173/305 (56%), Gaps = 16/305 (5%)
Query: 186 FRQYRVLGKGGFGEVCACQ-VRAT--GKMYACKKLEKKRI-KKRKGEAMALNEKQILEKV 241
F RVLGKGG+G+V + V+ T GK+YA K L K +I + K A E+ ILE V
Sbjct: 67 FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESV 126
Query: 242 NSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLED 301
F+V LAYA++T L L+L ++GG+L H+ G F E A FY AEI L
Sbjct: 127 KHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGI--FLEDTACFYLAEITLALGH 184
Query: 302 LHRERIVYRDLKPENILLDDHGHIRISDLGLAVH-VPEGQTIKGRVGTVGYMAPEVVKNE 360
LH + I+YRDLKPENI+L GHI+++D GL + EG GT+ YMAPE++
Sbjct: 185 LHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRS 244
Query: 361 RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC 420
+ + DWW+LG L+Y+M+ G PF +K +++ R +P +P AR L
Sbjct: 245 GHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALP----PYLTPDARDLV 300
Query: 421 SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI 480
+ L ++P++R+G G A +V+ HP F+ +N+ L A ++PPF+P Q+ D+
Sbjct: 301 KKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQS-----EEDV 355
Query: 481 EQFST 485
QF T
Sbjct: 356 SQFDT 360
>gi|32528297 ribosomal protein S6 kinase, polypeptide 5 isoform b
[Homo sapiens]
Length = 549
Score = 196 bits (499), Expect = 4e-50
Identities = 119/318 (37%), Positives = 181/318 (56%), Gaps = 17/318 (5%)
Query: 186 FRQYRVLGKGGFGEVCACQVRA---TGKMYACKKLEKKRI-KKRKGEAMALNEKQILEKV 241
F +VLG G +G+V + + TGK+YA K L+K I +K K E+Q+LE +
Sbjct: 49 FELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHI 108
Query: 242 N-SRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE 300
S F+V+L YA++T+ L L+L +NGG+L H+ + F E Y EI LE
Sbjct: 109 RQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRER--FTEHEVQIYVGEIVLALE 166
Query: 301 DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGR--VGTVGYMAPEVVK 358
LH+ I+YRD+K ENILLD +GH+ ++D GL+ +T + GT+ YMAP++V+
Sbjct: 167 HLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVR 226
Query: 359 --NERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQA 416
+ + + DWW+LG L+YE++ G SPF +K + E+ R + + Y + S A
Sbjct: 227 GGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALA 286
Query: 417 RSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKD 476
+ L +LL KDP +RLGC A E+KEH F+K+N+ L A + PFKP +D
Sbjct: 287 KDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKP-----VIRD 341
Query: 477 VLDIEQFSTVKGVELEPT 494
LD+ F+ + E++PT
Sbjct: 342 ELDVSNFAE-EFTEMDPT 358
Score = 40.8 bits (94), Expect = 0.004
Identities = 32/124 (25%), Positives = 55/124 (44%), Gaps = 7/124 (5%)
Query: 192 LGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRFVVSLAY 251
LG+G F C + + + +A K + K+ + E AL + +V L
Sbjct: 432 LGEGSFSICRKCVHKKSNQAFAVKIISKRMEANTQKEITALKLCE-----GHPNIVKLHE 486
Query: 252 AYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRERIVYRD 311
+ + LV+ L+NGG+L I + F E A + ++ + +H +V+RD
Sbjct: 487 VFHDQLHTFLVMELLNGGELFERIKK--KKHFSETEASYIMRKLVSAVSHMHDVGVVHRD 544
Query: 312 LKPE 315
LKPE
Sbjct: 545 LKPE 548
>gi|32528295 ribosomal protein S6 kinase, polypeptide 5 isoform a
[Homo sapiens]
Length = 802
Score = 196 bits (499), Expect = 4e-50
Identities = 119/318 (37%), Positives = 181/318 (56%), Gaps = 17/318 (5%)
Query: 186 FRQYRVLGKGGFGEVCACQVRA---TGKMYACKKLEKKRI-KKRKGEAMALNEKQILEKV 241
F +VLG G +G+V + + TGK+YA K L+K I +K K E+Q+LE +
Sbjct: 49 FELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHI 108
Query: 242 N-SRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE 300
S F+V+L YA++T+ L L+L +NGG+L H+ + F E Y EI LE
Sbjct: 109 RQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRER--FTEHEVQIYVGEIVLALE 166
Query: 301 DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGR--VGTVGYMAPEVVK 358
LH+ I+YRD+K ENILLD +GH+ ++D GL+ +T + GT+ YMAP++V+
Sbjct: 167 HLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVR 226
Query: 359 --NERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQA 416
+ + + DWW+LG L+YE++ G SPF +K + E+ R + + Y + S A
Sbjct: 227 GGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALA 286
Query: 417 RSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKD 476
+ L +LL KDP +RLGC A E+KEH F+K+N+ L A + PFKP +D
Sbjct: 287 KDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKP-----VIRD 341
Query: 477 VLDIEQFSTVKGVELEPT 494
LD+ F+ + E++PT
Sbjct: 342 ELDVSNFAE-EFTEMDPT 358
Score = 101 bits (251), Expect = 2e-21
Identities = 74/256 (28%), Positives = 120/256 (46%), Gaps = 18/256 (7%)
Query: 192 LGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRFVVSLAY 251
LG+G F C + + + +A K + K+ + E AL + +V L
Sbjct: 432 LGEGSFSICRKCVHKKSNQAFAVKIISKRMEANTQKEITALKLCE-----GHPNIVKLHE 486
Query: 252 AYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRERIVYRD 311
+ + LV+ L+NGG+L I + F E A + ++ + +H +V+RD
Sbjct: 487 VFHDQLHTFLVMELLNGGELFERIKK--KKHFSETEASYIMRKLVSAVSHMHDVGVVHRD 544
Query: 312 LKPENILLDDHG---HIRISDLGLA-VHVPEGQTIKGRVGTVGYMAPEVVKNERYTFSPD 367
LKPEN+L D I+I D G A + P+ Q +K T+ Y APE++ Y S D
Sbjct: 545 LKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQNGYDESCD 604
Query: 368 WWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPE-------EYSERFSPQARSLC 420
W+LG +LY M++GQ PFQ + + ++K++ + E + S +A+ L
Sbjct: 605 LWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLI 664
Query: 421 SQLLCKDPAERLGCRG 436
LL DP +RL G
Sbjct: 665 QGLLTVDPNKRLKMSG 680
>gi|4506737 ribosomal protein S6 kinase, 70kDa, polypeptide 1 [Homo
sapiens]
Length = 525
Score = 196 bits (498), Expect = 5e-50
Identities = 114/296 (38%), Positives = 170/296 (57%), Gaps = 15/296 (5%)
Query: 179 QPVTKNTFRQYRVLGKGGFGEVCACQVRA-----TGKMYACKKLEKKRI-KKRKGEAMAL 232
+ + F RVLGKGG+G+V QVR TGK++A K L+K I + K A
Sbjct: 84 EKIRPECFELLRVLGKGGYGKVF--QVRKVTGANTGKIFAMKVLKKAMIVRNAKDTAHTK 141
Query: 233 NEKQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYA 292
E+ ILE+V F+V L YA++T L L+L ++GG+L + G F E A FY
Sbjct: 142 AERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGI--FMEDTACFYL 199
Query: 293 AEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVH-VPEGQTIKGRVGTVGY 351
AEI L LH++ I+YRDLKPENI+L+ GH++++D GL + +G GT+ Y
Sbjct: 200 AEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGTIEY 259
Query: 352 MAPEVVKNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSER 411
MAPE++ + + DWW+LG L+Y+M+ G PF +K +++ + +P ++
Sbjct: 260 MAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYLTQ- 318
Query: 412 FSPQARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKP 467
+AR L +LL ++ A RLG G A EV+ HP F+ +N++ L A +EPPFKP
Sbjct: 319 ---EARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEELLARKVEPPFKP 371
>gi|47157325 protein kinase C, delta [Homo sapiens]
Length = 676
Score = 195 bits (495), Expect = 1e-49
Identities = 109/286 (38%), Positives = 165/286 (57%), Gaps = 12/286 (4%)
Query: 184 NTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILE-KVN 242
N F ++VLGKG FG+V +++ G+ +A K L+K + + EK++L
Sbjct: 347 NNFIFHKVLGKGSFGKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTMVEKRVLTLAAE 406
Query: 243 SRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDL 302
+ F+ L ++TKD L V+ +NGGDL +HI G+ F RA FYAAEI CGL+ L
Sbjct: 407 NPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGR--FELYRATFYAAEIMCGLQFL 464
Query: 303 HRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGR-VGTVGYMAPEVVKNER 361
H + I+YRDLK +N+LLD GHI+I+D G+ G++ GT Y+APE+++ +
Sbjct: 465 HSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLK 524
Query: 362 YTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLCS 421
YTFS DWW+ G LLYEM+ GQSPF + +E+ ++ Y + +++ +
Sbjct: 525 YTFSVDWWSFGVLLYEMLIGQSPFHGDDE----DELFESIRVDTPHYPRWITKESKDILE 580
Query: 422 QLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKP 467
+L ++P +RLG G +K HP FK +N+ L LEPPF+P
Sbjct: 581 KLFEREPTKRLGVTG----NIKIHPFFKTINWTLLEKRRLEPPFRP 622
>gi|31377782 protein kinase C, delta [Homo sapiens]
Length = 676
Score = 195 bits (495), Expect = 1e-49
Identities = 109/286 (38%), Positives = 165/286 (57%), Gaps = 12/286 (4%)
Query: 184 NTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILE-KVN 242
N F ++VLGKG FG+V +++ G+ +A K L+K + + EK++L
Sbjct: 347 NNFIFHKVLGKGSFGKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTMVEKRVLTLAAE 406
Query: 243 SRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDL 302
+ F+ L ++TKD L V+ +NGGDL +HI G+ F RA FYAAEI CGL+ L
Sbjct: 407 NPFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGR--FELYRATFYAAEIMCGLQFL 464
Query: 303 HRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGR-VGTVGYMAPEVVKNER 361
H + I+YRDLK +N+LLD GHI+I+D G+ G++ GT Y+APE+++ +
Sbjct: 465 HSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLK 524
Query: 362 YTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLCS 421
YTFS DWW+ G LLYEM+ GQSPF + +E+ ++ Y + +++ +
Sbjct: 525 YTFSVDWWSFGVLLYEMLIGQSPFHGDDE----DELFESIRVDTPHYPRWITKESKDILE 580
Query: 422 QLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKP 467
+L ++P +RLG G +K HP FK +N+ L LEPPF+P
Sbjct: 581 KLFEREPTKRLGVTG----NIKIHPFFKTINWTLLEKRRLEPPFRP 622
>gi|75709228 protein kinase C, zeta isoform 2 [Homo sapiens]
Length = 409
Score = 193 bits (490), Expect = 4e-49
Identities = 114/318 (35%), Positives = 172/318 (54%), Gaps = 10/318 (3%)
Query: 186 FRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSR- 244
F RV+G+G + +V +++ ++YA K ++K+ + + EK + E+ +S
Sbjct: 69 FDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASSNP 128
Query: 245 FVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHR 304
F+V L ++T L LV+ +NGGDL FH+ Q PE A FYAAEIC L LH
Sbjct: 129 FLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQR--QRKLPEEHARFYAAEICIALNFLHE 186
Query: 305 ERIVYRDLKPENILLDDHGHIRISDLGLAVH-VPEGQTIKGRVGTVGYMAPEVVKNERYT 363
I+YRDLK +N+LLD GHI+++D G+ + G T GT Y+APE+++ E Y
Sbjct: 187 RGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEYG 246
Query: 364 FSPDWWALGCLLYEMIAGQSPFQ---QRKKKIKREEVERLVKEVPEEYSERFSPQARSLC 420
FS DWWALG L++EM+AG+SPF + + +++ E P S +A +
Sbjct: 247 FSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHVL 306
Query: 421 SQLLCKDPAERLGCRGGSA-REVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLD 479
L KDP ERLGCR + ++K H F+ +++ L PPF+P Y D D
Sbjct: 307 KGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNFD 366
Query: 480 IEQFSTVKGVELEPTDQD 497
+ T + V+L P D+D
Sbjct: 367 TQ--FTSEPVQLTPDDED 382
>gi|75709226 protein kinase C, zeta isoform 2 [Homo sapiens]
Length = 409
Score = 193 bits (490), Expect = 4e-49
Identities = 114/318 (35%), Positives = 172/318 (54%), Gaps = 10/318 (3%)
Query: 186 FRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSR- 244
F RV+G+G + +V +++ ++YA K ++K+ + + EK + E+ +S
Sbjct: 69 FDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASSNP 128
Query: 245 FVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHR 304
F+V L ++T L LV+ +NGGDL FH+ Q PE A FYAAEIC L LH
Sbjct: 129 FLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQR--QRKLPEEHARFYAAEICIALNFLHE 186
Query: 305 ERIVYRDLKPENILLDDHGHIRISDLGLAVH-VPEGQTIKGRVGTVGYMAPEVVKNERYT 363
I+YRDLK +N+LLD GHI+++D G+ + G T GT Y+APE+++ E Y
Sbjct: 187 RGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEYG 246
Query: 364 FSPDWWALGCLLYEMIAGQSPFQ---QRKKKIKREEVERLVKEVPEEYSERFSPQARSLC 420
FS DWWALG L++EM+AG+SPF + + +++ E P S +A +
Sbjct: 247 FSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHVL 306
Query: 421 SQLLCKDPAERLGCRGGSA-REVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLD 479
L KDP ERLGCR + ++K H F+ +++ L PPF+P Y D D
Sbjct: 307 KGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNFD 366
Query: 480 IEQFSTVKGVELEPTDQD 497
+ T + V+L P D+D
Sbjct: 367 TQ--FTSEPVQLTPDDED 382
>gi|52486327 protein kinase C, zeta isoform 1 [Homo sapiens]
Length = 592
Score = 193 bits (490), Expect = 4e-49
Identities = 114/318 (35%), Positives = 172/318 (54%), Gaps = 10/318 (3%)
Query: 186 FRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSR- 244
F RV+G+G + +V +++ ++YA K ++K+ + + EK + E+ +S
Sbjct: 252 FDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASSNP 311
Query: 245 FVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHR 304
F+V L ++T L LV+ +NGGDL FH+ Q PE A FYAAEIC L LH
Sbjct: 312 FLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQR--QRKLPEEHARFYAAEICIALNFLHE 369
Query: 305 ERIVYRDLKPENILLDDHGHIRISDLGLAVH-VPEGQTIKGRVGTVGYMAPEVVKNERYT 363
I+YRDLK +N+LLD GHI+++D G+ + G T GT Y+APE+++ E Y
Sbjct: 370 RGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEYG 429
Query: 364 FSPDWWALGCLLYEMIAGQSPFQ---QRKKKIKREEVERLVKEVPEEYSERFSPQARSLC 420
FS DWWALG L++EM+AG+SPF + + +++ E P S +A +
Sbjct: 430 FSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHVL 489
Query: 421 SQLLCKDPAERLGCRGGSA-REVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLD 479
L KDP ERLGCR + ++K H F+ +++ L PPF+P Y D D
Sbjct: 490 KGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNFD 549
Query: 480 IEQFSTVKGVELEPTDQD 497
+ T + V+L P D+D
Sbjct: 550 TQ--FTSEPVQLTPDDED 565
>gi|133908623 protein kinase C, iota [Homo sapiens]
Length = 596
Score = 192 bits (487), Expect = 9e-49
Identities = 113/324 (34%), Positives = 176/324 (54%), Gaps = 12/324 (3%)
Query: 186 FRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKV-NSR 244
F RV+G+G + +V +++ T ++YA K ++K+ + + EK + E+ N
Sbjct: 254 FDLLRVIGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHP 313
Query: 245 FVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHR 304
F+V L ++T+ L V+ +NGGDL FH+ Q PE A FY+AEI L LH
Sbjct: 314 FLVGLHSCFQTESRLFFVIEYVNGGDLMFHMQR--QRKLPEEHARFYSAEISLALNYLHE 371
Query: 305 ERIVYRDLKPENILLDDHGHIRISDLGLAVH-VPEGQTIKGRVGTVGYMAPEVVKNERYT 363
I+YRDLK +N+LLD GHI+++D G+ + G T GT Y+APE+++ E Y
Sbjct: 372 RGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYG 431
Query: 364 FSPDWWALGCLLYEMIAGQSPF-----QQRKKKIKREEVERLVKEVPEEYSERFSPQARS 418
FS DWWALG L++EM+AG+SPF + + + +++ E S +A S
Sbjct: 432 FSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAAS 491
Query: 419 LCSQLLCKDPAERLGCRGGSA-REVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDV 477
+ L KDP ERLGC + +++ HP F+ +++ + + PPFKP+ + D
Sbjct: 492 VLKSFLNKDPKERLGCHPQTGFADIQGHPFFRNVDWDMMEQKQVVPPFKPNISGEFGLDN 551
Query: 478 LDIEQFSTVKGVELEPTDQDFYQK 501
D QF T + V+L P D D +K
Sbjct: 552 FD-SQF-TNEPVQLTPDDDDIVRK 573
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,392,584
Number of Sequences: 37866
Number of extensions: 1255578
Number of successful extensions: 6372
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 689
Number of HSP's successfully gapped in prelim test: 110
Number of HSP's that attempted gapping in prelim test: 3975
Number of HSP's gapped (non-prelim): 1064
length of query: 589
length of database: 18,247,518
effective HSP length: 108
effective length of query: 481
effective length of database: 14,157,990
effective search space: 6809993190
effective search space used: 6809993190
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.