Guide to the Human Genome
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Name: GRK4 Sequence: fasta or formatted (578aa) NCBI GI: 51873043
Description:

G protein-coupled receptor kinase 4 isoform alpha

Referenced in:

G-Protein-coupled Receptors

Other entries for this name:
alt prot [546aa] G protein-coupled receptor kinase 4 isoform beta
alt prot [532aa] G protein-coupled receptor kinase 4 isoform gamma
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.4         31           2
 C cysteine            3.6         21           2
 D aspartate           5.7         33           2
 E glutamate           9.5         55           2
 F phenylalanine       4.8         28           2
 G glycine             6.6         38           2
 H histidine           1.7         10           1
 I isoleucine          4.7         27           1
 K lysine              8.7         50           2
 L leucine             9.0         52           3
 M methionine          1.7         10           1
 N asparagine          3.6         21           2
 P proline             5.0         29           2
 Q glutamine           3.5         20           1
 R arginine            7.1         41           2
 S serine              5.2         30           2
 T threonine           3.3         19           1
 V valine              5.9         34           2
 W tryptophan          1.2          7           2
 Y tyrosine            3.8         22           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   G protein-coupled receptor kinase 4 isoform alpha [H... 
GRK4                  0.929   G protein-coupled receptor kinase 4 isoform beta [Ho...
GRK4                  0.901   G protein-coupled receptor kinase 4 isoform gamma [H...
GRK5                  0.658   G protein-coupled receptor kinase 5 
GRK6                  0.650   G protein-coupled receptor kinase 6 isoform A 
GRK6                  0.647   G protein-coupled receptor kinase 6 isoform C 
GRK6                  0.647   G protein-coupled receptor kinase 6 isoform B 
GRK1                  0.408   rhodopsin kinase 
GRK7                  0.400   G-protein-coupled receptor kinase 7 
ADRBK2                0.244   beta-adrenergic receptor kinase 2 
ADRBK1                0.235   beta-adrenergic receptor kinase 1 
PRKCD                 0.157   protein kinase C, delta 
PRKCD                 0.157   protein kinase C, delta 
PRKCA                 0.155   protein kinase C, alpha 
PRKCB                 0.155   protein kinase C, beta isoform 1 
PRKCB                 0.155   protein kinase C, beta isoform 2 
PKN1                  0.154   protein kinase N1 isoform 1 
PKN1                  0.154   protein kinase N1 isoform 2 
PKN2                  0.153   protein kinase N2 
AKT3                  0.150   AKT3 kinase isoform 1 
AKT3                  0.150   AKT3 kinase isoform 2 
PRKCH                 0.150   protein kinase C, eta 
AKT2                  0.149   AKT2 kinase 
AKT1                  0.147   AKT1 kinase 
AKT1                  0.147   AKT1 kinase 
AKT1                  0.147   AKT1 kinase 
PRKCQ                 0.146   protein kinase C, theta 
PRKCG                 0.144   protein kinase C, gamma 
PRKCE                 0.143   protein kinase C, epsilon 
RPS6KB2               0.137   ribosomal protein S6 kinase, 70kDa, polypeptide 2 [H...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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