Guide to the Human Genome
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Search of human proteins with 5174655

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5174655 reticulon 3 isoform a [Homo sapiens]
         (236 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5174655 reticulon 3 isoform a [Homo sapiens]                       457   e-129
gi|41393604 reticulon 3 isoform c [Homo sapiens]                      445   e-125
gi|41393606 reticulon 3 isoform d [Homo sapiens]                      392   e-109
gi|41393608 reticulon 3 isoform b [Homo sapiens]                      363   e-101
gi|24431933 reticulon 4 isoform B [Homo sapiens]                      252   2e-67
gi|47519490 reticulon 4 isoform D [Homo sapiens]                      250   7e-67
gi|47519562 reticulon 4 isoform E [Homo sapiens]                      246   2e-65
gi|24431935 reticulon 4 isoform A [Homo sapiens]                      246   2e-65
gi|5902016 reticulon 4 isoform C [Homo sapiens]                       244   6e-65
gi|45827778 reticulon 1 isoform B [Homo sapiens]                      238   4e-63
gi|10863935 reticulon 1 isoform A [Homo sapiens]                      238   4e-63
gi|45827776 reticulon 1 isoform C [Homo sapiens]                      233   8e-62
gi|5032055 reticulon 2 isoform A [Homo sapiens]                       171   5e-43
gi|46255007 reticulon 2 isoform C [Homo sapiens]                      171   5e-43
gi|46255005 reticulon 2 isoform B [Homo sapiens]                      171   5e-43
gi|167000400 gamma-aminobutyric acid (GABA) B receptor 1 isoform...    30   1.8  
gi|11497612 gamma-aminobutyric acid (GABA) B receptor 1 isoform ...    30   1.8  
gi|10835015 gamma-aminobutyric acid (GABA) B receptor 1 isoform ...    30   1.8  
gi|84993742 tripartite motif-containing 71 [Homo sapiens]              30   2.4  
gi|65786661 BTB (POZ) domain containing 11 isoform a [Homo sapiens]    30   2.4  
gi|31543906 ubiquitin-conjugating enzyme E2Q [Homo sapiens]            29   3.1  
gi|58218984 single stranded DNA binding protein 4 isoform b [Hom...    29   3.1  
gi|155722994 zinc finger CCCH-type containing 3 [Homo sapiens]         29   3.1  
gi|14249150 single stranded DNA binding protein 4 isoform a [Hom...    29   3.1  
gi|13994287 BTE-binding protein 4 [Homo sapiens]                       29   4.0  
gi|94536854 thrombospondin, type I, domain containing 4 [Homo sa...    28   5.3  
gi|115334682 SNAP25-interacting protein [Homo sapiens]                 28   5.3  
gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens]                      28   5.3  
gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens]          28   5.3  
gi|45827800 prestin isoform b [Homo sapiens]                           28   6.9  

>gi|5174655 reticulon 3 isoform a [Homo sapiens]
          Length = 236

 Score =  457 bits (1175), Expect = e-129
 Identities = 236/236 (100%), Positives = 236/236 (100%)

Query: 1   MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCAVHDLIFWRDVKKT 60
           MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCAVHDLIFWRDVKKT
Sbjct: 1   MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCAVHDLIFWRDVKKT 60

Query: 61  GFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYL 120
           GFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYL
Sbjct: 61  GFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYL 120

Query: 121 DVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNG 180
           DVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNG
Sbjct: 121 DVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNG 180

Query: 181 ITLLILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE 236
           ITLLILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE
Sbjct: 181 ITLLILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE 236


>gi|41393604 reticulon 3 isoform c [Homo sapiens]
          Length = 255

 Score =  445 bits (1145), Expect = e-125
 Identities = 236/255 (92%), Positives = 236/255 (92%), Gaps = 19/255 (7%)

Query: 1   MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCA------------- 47
           MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCA             
Sbjct: 1   MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCADSFVSSSSSQPVS 60

Query: 48  ------VHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYK 101
                 VHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYK
Sbjct: 61  LFSTSQVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYK 120

Query: 102 SVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDS 161
           SVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDS
Sbjct: 121 SVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDS 180

Query: 162 LKLAVFMWLMTYVGAVFNGITLLILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVE 221
           LKLAVFMWLMTYVGAVFNGITLLILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVE
Sbjct: 181 LKLAVFMWLMTYVGAVFNGITLLILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVE 240

Query: 222 KIQAKLPGIAKKKAE 236
           KIQAKLPGIAKKKAE
Sbjct: 241 KIQAKLPGIAKKKAE 255


>gi|41393606 reticulon 3 isoform d [Homo sapiens]
          Length = 241

 Score =  392 bits (1007), Expect = e-109
 Identities = 202/202 (100%), Positives = 202/202 (100%)

Query: 1   MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCAVHDLIFWRDVKKT 60
           MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCAVHDLIFWRDVKKT
Sbjct: 1   MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCAVHDLIFWRDVKKT 60

Query: 61  GFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYL 120
           GFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYL
Sbjct: 61  GFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYL 120

Query: 121 DVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNG 180
           DVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNG
Sbjct: 121 DVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNG 180

Query: 181 ITLLILAELLIFSVPIVYEKYK 202
           ITLLILAELLIFSVPIVYEKYK
Sbjct: 181 ITLLILAELLIFSVPIVYEKYK 202


>gi|41393608 reticulon 3 isoform b [Homo sapiens]
          Length = 1013

 Score =  363 bits (931), Expect = e-101
 Identities = 189/190 (99%), Positives = 190/190 (100%)

Query: 47   AVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVIQA 106
            +VHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVIQA
Sbjct: 824  SVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVIQA 883

Query: 107  VQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLKLAV 166
            VQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLKLAV
Sbjct: 884  VQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLKLAV 943

Query: 167  FMWLMTYVGAVFNGITLLILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAK 226
            FMWLMTYVGAVFNGITLLILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAK
Sbjct: 944  FMWLMTYVGAVFNGITLLILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAK 1003

Query: 227  LPGIAKKKAE 236
            LPGIAKKKAE
Sbjct: 1004 LPGIAKKKAE 1013



 Score = 99.0 bits (245), Expect = 3e-21
 Identities = 47/47 (100%), Positives = 47/47 (100%)

Query: 1  MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCA 47
          MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCA
Sbjct: 1  MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSSCA 47


>gi|24431933 reticulon 4 isoform B [Homo sapiens]
          Length = 373

 Score =  252 bits (643), Expect = 2e-67
 Identities = 123/215 (57%), Positives = 162/215 (75%), Gaps = 2/215 (0%)

Query: 22  PSAPGGGGSPGACPALGTKSCSSSCAVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVIS 81
           P AP     P   PA   +  SS   V DL++WRD+KKTG VFG +L +LLSL  FS++S
Sbjct: 161 PPAPAPAAPPST-PAAPKRRGSSGSVVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVS 219

Query: 82  VVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVH 141
           V +Y+ LALLSVTISFRIYK VIQA+QKS+EGHPF+AYL+ ++ +S E    Y N+A+ H
Sbjct: 220 VTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSALGH 279

Query: 142 INRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLIFSVPIVYEKY 201
           +N  +K + RLFLV+DLVDSLK AV MW+ TYVGA+FNG+TLLILA + +FSVP++YE++
Sbjct: 280 VNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYERH 339

Query: 202 KTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE 236
           + QIDHY+G+A    K  + KIQAK+PG+ K+KAE
Sbjct: 340 QAQIDHYLGLANKNVKDAMAKIQAKIPGL-KRKAE 373


>gi|47519490 reticulon 4 isoform D [Homo sapiens]
          Length = 392

 Score =  250 bits (639), Expect = 7e-67
 Identities = 127/222 (57%), Positives = 166/222 (74%), Gaps = 9/222 (4%)

Query: 22  PSAPGGGGSPG-------ACPALGTKSCSSSCAVHDLIFWRDVKKTGFVFGTTLIMLLSL 74
           P+AP   GS G       A PA       SS AV DL++WRD+KKTG VFG +L +LLSL
Sbjct: 173 PAAPKRRGSSGSVDETLFALPAASEPVIRSS-AVVDLLYWRDIKKTGVVFGASLFLLLSL 231

Query: 75  AAFSVISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNY 134
             FS++SV +Y+ LALLSVTISFRIYK VIQA+QKS+EGHPF+AYL+ ++ +S E    Y
Sbjct: 232 TVFSIVSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKY 291

Query: 135 MNAAMVHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLIFSV 194
            N+A+ H+N  +K + RLFLV+DLVDSLK AV MW+ TYVGA+FNG+TLLILA + +FSV
Sbjct: 292 SNSALGHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSV 351

Query: 195 PIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE 236
           P++YE+++ QIDHY+G+A    K  + KIQAK+PG+ K+KAE
Sbjct: 352 PVIYERHQAQIDHYLGLANKNVKDAMAKIQAKIPGL-KRKAE 392


>gi|47519562 reticulon 4 isoform E [Homo sapiens]
          Length = 986

 Score =  246 bits (627), Expect = 2e-65
 Identities = 120/217 (55%), Positives = 161/217 (74%), Gaps = 1/217 (0%)

Query: 20  AEPSAPGGGGSPGACPALGTKSCSSSCAVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSV 79
           AE   P         P+    +  S  +V DL++WRD+KKTG VFG +L +LLSL  FS+
Sbjct: 771 AEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSI 830

Query: 80  ISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAM 139
           +SV +Y+ LALLSVTISFRIYK VIQA+QKS+EGHPF+AYL+ ++ +S E    Y N+A+
Sbjct: 831 VSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSAL 890

Query: 140 VHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLIFSVPIVYE 199
            H+N  +K + RLFLV+DLVDSLK AV MW+ TYVGA+FNG+TLLILA + +FSVP++YE
Sbjct: 891 GHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYE 950

Query: 200 KYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE 236
           +++ QIDHY+G+A    K  + KIQAK+PG+ K+KAE
Sbjct: 951 RHQAQIDHYLGLANKNVKDAMAKIQAKIPGL-KRKAE 986


>gi|24431935 reticulon 4 isoform A [Homo sapiens]
          Length = 1192

 Score =  246 bits (627), Expect = 2e-65
 Identities = 120/217 (55%), Positives = 161/217 (74%), Gaps = 1/217 (0%)

Query: 20   AEPSAPGGGGSPGACPALGTKSCSSSCAVHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSV 79
            AE   P         P+    +  S  +V DL++WRD+KKTG VFG +L +LLSL  FS+
Sbjct: 977  AEKKLPSDTEKEDRSPSAIFSAELSKTSVVDLLYWRDIKKTGVVFGASLFLLLSLTVFSI 1036

Query: 80   ISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHNYMNAAM 139
            +SV +Y+ LALLSVTISFRIYK VIQA+QKS+EGHPF+AYL+ ++ +S E    Y N+A+
Sbjct: 1037 VSVTAYIALALLSVTISFRIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNSAL 1096

Query: 140  VHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLIFSVPIVYE 199
             H+N  +K + RLFLV+DLVDSLK AV MW+ TYVGA+FNG+TLLILA + +FSVP++YE
Sbjct: 1097 GHVNCTIKELRRLFLVDDLVDSLKFAVLMWVFTYVGALFNGLTLLILALISLFSVPVIYE 1156

Query: 200  KYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE 236
            +++ QIDHY+G+A    K  + KIQAK+PG+ K+KAE
Sbjct: 1157 RHQAQIDHYLGLANKNVKDAMAKIQAKIPGL-KRKAE 1192


>gi|5902016 reticulon 4 isoform C [Homo sapiens]
          Length = 199

 Score =  244 bits (622), Expect = 6e-65
 Identities = 115/189 (60%), Positives = 153/189 (80%), Gaps = 1/189 (0%)

Query: 48  VHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAV 107
           V DL++WRD+KKTG VFG +L +LLSL  FS++SV +Y+ LALLSVTISFRIYK VIQA+
Sbjct: 12  VVDLLYWRDIKKTGVVFGASLFLLLSLTVFSIVSVTAYIALALLSVTISFRIYKGVIQAI 71

Query: 108 QKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLKLAVF 167
           QKS+EGHPF+AYL+ ++ +S E    Y N+A+ H+N  +K + RLFLV+DLVDSLK AV 
Sbjct: 72  QKSDEGHPFRAYLESEVAISEELVQKYSNSALGHVNCTIKELRRLFLVDDLVDSLKFAVL 131

Query: 168 MWLMTYVGAVFNGITLLILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKL 227
           MW+ TYVGA+FNG+TLLILA + +FSVP++YE+++ QIDHY+G+A    K  + KIQAK+
Sbjct: 132 MWVFTYVGALFNGLTLLILALISLFSVPVIYERHQAQIDHYLGLANKNVKDAMAKIQAKI 191

Query: 228 PGIAKKKAE 236
           PG+ K+KAE
Sbjct: 192 PGL-KRKAE 199


>gi|45827778 reticulon 1 isoform B [Homo sapiens]
          Length = 356

 Score =  238 bits (606), Expect = 4e-63
 Identities = 123/223 (55%), Positives = 164/223 (73%), Gaps = 6/223 (2%)

Query: 16  SSFGAEPSAPGGGG--SPGACPALGTKSCSSSCAVHDLIFWRDVKKTGFVFGTTLIMLLS 73
           SS    P+A  G G   PGA P L   +   +    DL++WRD+K+TG VFG+ L++L S
Sbjct: 138 SSSNQSPAATKGPGPLGPGAPPPLLFLNKQKAI---DLLYWRDIKQTGIVFGSFLLLLFS 194

Query: 74  LAAFSVISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHN 133
           L  FSV+SVV+YL LA LS TISFRIYKSV+QAVQK++EGHPFKAYL+++ITLS E    
Sbjct: 195 LTQFSVVSVVAYLALAALSATISFRIYKSVLQAVQKTDEGHPFKAYLELEITLSQEQIQK 254

Query: 134 YMNAAMVHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLIFS 193
           Y +    ++N  LK + RLFLV+DLVDSLK AV MWL+TYVGA+FNG+TLL++A + +F+
Sbjct: 255 YTDCLQFYVNSTLKELRRLFLVQDLVDSLKFAVLMWLLTYVGALFNGLTLLLMAVVSMFT 314

Query: 194 VPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE 236
           +P+VY K++ QID Y+G+ R    ++V KIQAK+PG AK+ AE
Sbjct: 315 LPVVYVKHQAQIDQYLGLVRTHINAVVAKIQAKIPG-AKRHAE 356


>gi|10863935 reticulon 1 isoform A [Homo sapiens]
          Length = 776

 Score =  238 bits (606), Expect = 4e-63
 Identities = 123/223 (55%), Positives = 164/223 (73%), Gaps = 6/223 (2%)

Query: 16  SSFGAEPSAPGGGG--SPGACPALGTKSCSSSCAVHDLIFWRDVKKTGFVFGTTLIMLLS 73
           SS    P+A  G G   PGA P L   +   +    DL++WRD+K+TG VFG+ L++L S
Sbjct: 558 SSSNQSPAATKGPGPLGPGAPPPLLFLNKQKAI---DLLYWRDIKQTGIVFGSFLLLLFS 614

Query: 74  LAAFSVISVVSYLILALLSVTISFRIYKSVIQAVQKSEEGHPFKAYLDVDITLSSEAFHN 133
           L  FSV+SVV+YL LA LS TISFRIYKSV+QAVQK++EGHPFKAYL+++ITLS E    
Sbjct: 615 LTQFSVVSVVAYLALAALSATISFRIYKSVLQAVQKTDEGHPFKAYLELEITLSQEQIQK 674

Query: 134 YMNAAMVHINRALKLIIRLFLVEDLVDSLKLAVFMWLMTYVGAVFNGITLLILAELLIFS 193
           Y +    ++N  LK + RLFLV+DLVDSLK AV MWL+TYVGA+FNG+TLL++A + +F+
Sbjct: 675 YTDCLQFYVNSTLKELRRLFLVQDLVDSLKFAVLMWLLTYVGALFNGLTLLLMAVVSMFT 734

Query: 194 VPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKLPGIAKKKAE 236
           +P+VY K++ QID Y+G+ R    ++V KIQAK+PG AK+ AE
Sbjct: 735 LPVVYVKHQAQIDQYLGLVRTHINAVVAKIQAKIPG-AKRHAE 776


>gi|45827776 reticulon 1 isoform C [Homo sapiens]
          Length = 208

 Score =  233 bits (595), Expect = 8e-62
 Identities = 112/187 (59%), Positives = 150/187 (80%), Gaps = 1/187 (0%)

Query: 50  DLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAVQK 109
           DL++WRD+K+TG VFG+ L++L SL  FSV+SVV+YL LA LS TISFRIYKSV+QAVQK
Sbjct: 23  DLLYWRDIKQTGIVFGSFLLLLFSLTQFSVVSVVAYLALAALSATISFRIYKSVLQAVQK 82

Query: 110 SEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLKLAVFMW 169
           ++EGHPFKAYL+++ITLS E    Y +    ++N  LK + RLFLV+DLVDSLK AV MW
Sbjct: 83  TDEGHPFKAYLELEITLSQEQIQKYTDCLQFYVNSTLKELRRLFLVQDLVDSLKFAVLMW 142

Query: 170 LMTYVGAVFNGITLLILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKLPG 229
           L+TYVGA+FNG+TLL++A + +F++P+VY K++ QID Y+G+ R    ++V KIQAK+PG
Sbjct: 143 LLTYVGALFNGLTLLLMAVVSMFTLPVVYVKHQAQIDQYLGLVRTHINAVVAKIQAKIPG 202

Query: 230 IAKKKAE 236
            AK+ AE
Sbjct: 203 -AKRHAE 208


>gi|5032055 reticulon 2 isoform A [Homo sapiens]
          Length = 545

 Score =  171 bits (433), Expect = 5e-43
 Identities = 82/182 (45%), Positives = 125/182 (68%)

Query: 48  VHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAV 107
           V DL++W+D + +G VF   ++ LL L  FS++SV ++L L LL  TIS R+Y+ V+QAV
Sbjct: 345 VADLLYWKDTRTSGVVFTGLMVSLLCLLHFSIVSVAAHLALLLLCGTISLRVYRKVLQAV 404

Query: 108 QKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLKLAVF 167
            + +  +PF+AYLDVD+TL+ E      +     +  A   +   FLVEDLVDSLKLA+ 
Sbjct: 405 HRGDGANPFQAYLDVDLTLTREQTERLSHQITSRVVSAATQLRHFFLVEDLVDSLKLALL 464

Query: 168 MWLMTYVGAVFNGITLLILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKL 227
            +++T+VGA+FNG+TLLIL  + +F++P++Y +++ QID YVG+  +Q   I  KI+AK+
Sbjct: 465 FYILTFVGAIFNGLTLLILGVIGLFTIPLLYRQHQAQIDQYVGLVTNQLSHIKAKIRAKI 524

Query: 228 PG 229
           PG
Sbjct: 525 PG 526


>gi|46255007 reticulon 2 isoform C [Homo sapiens]
          Length = 205

 Score =  171 bits (433), Expect = 5e-43
 Identities = 82/182 (45%), Positives = 125/182 (68%)

Query: 48  VHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAV 107
           V DL++W+D + +G VF   ++ LL L  FS++SV ++L L LL  TIS R+Y+ V+QAV
Sbjct: 5   VADLLYWKDTRTSGVVFTGLMVSLLCLLHFSIVSVAAHLALLLLCGTISLRVYRKVLQAV 64

Query: 108 QKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLKLAVF 167
            + +  +PF+AYLDVD+TL+ E      +     +  A   +   FLVEDLVDSLKLA+ 
Sbjct: 65  HRGDGANPFQAYLDVDLTLTREQTERLSHQITSRVVSAATQLRHFFLVEDLVDSLKLALL 124

Query: 168 MWLMTYVGAVFNGITLLILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKL 227
            +++T+VGA+FNG+TLLIL  + +F++P++Y +++ QID YVG+  +Q   I  KI+AK+
Sbjct: 125 FYILTFVGAIFNGLTLLILGVIGLFTIPLLYRQHQAQIDQYVGLVTNQLSHIKAKIRAKI 184

Query: 228 PG 229
           PG
Sbjct: 185 PG 186


>gi|46255005 reticulon 2 isoform B [Homo sapiens]
          Length = 472

 Score =  171 bits (433), Expect = 5e-43
 Identities = 82/182 (45%), Positives = 125/182 (68%)

Query: 48  VHDLIFWRDVKKTGFVFGTTLIMLLSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAV 107
           V DL++W+D + +G VF   ++ LL L  FS++SV ++L L LL  TIS R+Y+ V+QAV
Sbjct: 272 VADLLYWKDTRTSGVVFTGLMVSLLCLLHFSIVSVAAHLALLLLCGTISLRVYRKVLQAV 331

Query: 108 QKSEEGHPFKAYLDVDITLSSEAFHNYMNAAMVHINRALKLIIRLFLVEDLVDSLKLAVF 167
            + +  +PF+AYLDVD+TL+ E      +     +  A   +   FLVEDLVDSLKLA+ 
Sbjct: 332 HRGDGANPFQAYLDVDLTLTREQTERLSHQITSRVVSAATQLRHFFLVEDLVDSLKLALL 391

Query: 168 MWLMTYVGAVFNGITLLILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVEKIQAKL 227
            +++T+VGA+FNG+TLLIL  + +F++P++Y +++ QID YVG+  +Q   I  KI+AK+
Sbjct: 392 FYILTFVGAIFNGLTLLILGVIGLFTIPLLYRQHQAQIDQYVGLVTNQLSHIKAKIRAKI 451

Query: 228 PG 229
           PG
Sbjct: 452 PG 453


>gi|167000400 gamma-aminobutyric acid (GABA) B receptor 1 isoform c
           precursor [Homo sapiens]
          Length = 899

 Score = 30.0 bits (66), Expect = 1.8
 Identities = 16/40 (40%), Positives = 24/40 (60%)

Query: 72  LSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAVQKSE 111
           LS   F  +SV+S L + L  V +SF IY S ++ +Q S+
Sbjct: 525 LSQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQ 564


>gi|11497612 gamma-aminobutyric acid (GABA) B receptor 1 isoform b
           precursor [Homo sapiens]
          Length = 844

 Score = 30.0 bits (66), Expect = 1.8
 Identities = 16/40 (40%), Positives = 24/40 (60%)

Query: 72  LSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAVQKSE 111
           LS   F  +SV+S L + L  V +SF IY S ++ +Q S+
Sbjct: 470 LSQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQ 509


>gi|10835015 gamma-aminobutyric acid (GABA) B receptor 1 isoform a
           precursor [Homo sapiens]
          Length = 961

 Score = 30.0 bits (66), Expect = 1.8
 Identities = 16/40 (40%), Positives = 24/40 (60%)

Query: 72  LSLAAFSVISVVSYLILALLSVTISFRIYKSVIQAVQKSE 111
           LS   F  +SV+S L + L  V +SF IY S ++ +Q S+
Sbjct: 587 LSQKLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQ 626


>gi|84993742 tripartite motif-containing 71 [Homo sapiens]
          Length = 868

 Score = 29.6 bits (65), Expect = 2.4
 Identities = 14/30 (46%), Positives = 18/30 (60%)

Query: 4  PSAATQSHSISSSSFGAEPSAPGGGGSPGA 33
          P+  + + S SSSS     S+ GGGG PGA
Sbjct: 22 PAPLSSNSSASSSSSQTSTSSGGGGGGPGA 51


>gi|65786661 BTB (POZ) domain containing 11 isoform a [Homo sapiens]
          Length = 1104

 Score = 29.6 bits (65), Expect = 2.4
 Identities = 21/50 (42%), Positives = 25/50 (50%), Gaps = 7/50 (14%)

Query: 4   PSAATQSHSISSSSFGAEPS------APGGG-GSPGACPALGTKSCSSSC 46
           P + + S    SS  GA P+      APGGG  S GAC A  + S  SSC
Sbjct: 264 PGSGSGSGPGPSSGPGAAPAADKEREAPGGGAASGGACSAASSASGGSSC 313


>gi|31543906 ubiquitin-conjugating enzyme E2Q [Homo sapiens]
          Length = 422

 Score = 29.3 bits (64), Expect = 3.1
 Identities = 13/38 (34%), Positives = 16/38 (42%)

Query: 1  MAEPSAATQSHSISSSSFGAEPSAPGGGGSPGACPALG 38
          M +P    Q         G + +APG GG PG  P  G
Sbjct: 1  MQQPQPQGQQQPGPGQQLGGQGAAPGAGGGPGGGPGPG 38


>gi|58218984 single stranded DNA binding protein 4 isoform b [Homo
           sapiens]
          Length = 363

 Score = 29.3 bits (64), Expect = 3.1
 Identities = 20/45 (44%), Positives = 25/45 (55%), Gaps = 4/45 (8%)

Query: 4   PSAATQSHSI--SSSSFGAEPSAPGGGGSPGA--CPALGTKSCSS 44
           P A+   +SI  SSSS G+    PGGGG PG    P+ G  + SS
Sbjct: 220 PWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSS 264


>gi|155722994 zinc finger CCCH-type containing 3 [Homo sapiens]
          Length = 948

 Score = 29.3 bits (64), Expect = 3.1
 Identities = 13/36 (36%), Positives = 21/36 (58%)

Query: 10  SHSISSSSFGAEPSAPGGGGSPGACPALGTKSCSSS 45
           S ++++++  A P  PGG  SP +  A  + S SSS
Sbjct: 846 SAALTAAAVAAPPHCPGGSASPSSSKASSSSSSSSS 881


>gi|14249150 single stranded DNA binding protein 4 isoform a [Homo
           sapiens]
          Length = 385

 Score = 29.3 bits (64), Expect = 3.1
 Identities = 20/45 (44%), Positives = 25/45 (55%), Gaps = 4/45 (8%)

Query: 4   PSAATQSHSI--SSSSFGAEPSAPGGGGSPGA--CPALGTKSCSS 44
           P A+   +SI  SSSS G+    PGGGG PG    P+ G  + SS
Sbjct: 242 PWASPSGNSIPYSSSSPGSYTGPPGGGGPPGTPIMPSPGDSTNSS 286


>gi|13994287 BTE-binding protein 4 [Homo sapiens]
          Length = 252

 Score = 28.9 bits (63), Expect = 4.0
 Identities = 17/38 (44%), Positives = 21/38 (55%), Gaps = 2/38 (5%)

Query: 4   PSAATQSHSISSSSFGAEPSAPGGGGSPGACPALGTKS 41
           P AA    S +SSS  A  S+P  G +PGA P+   KS
Sbjct: 91  PGAAPGGASPASSSSAA--SSPSSGRAPGAAPSAAAKS 126


>gi|94536854 thrombospondin, type I, domain containing 4 [Homo
          sapiens]
          Length = 1018

 Score = 28.5 bits (62), Expect = 5.3
 Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 4/47 (8%)

Query: 4  PSAATQSHSISS--SSFGAEPSAPGGGGSPGACPALGT-KSCSSSCA 47
          P  +TQ   +    ++ GA P   GGGG+PG   A G   +CS SC+
Sbjct: 25 PQPSTQHRKVPQRMAAEGA-PEDDGGGGAPGVWGAWGPWSACSRSCS 70


>gi|115334682 SNAP25-interacting protein [Homo sapiens]
          Length = 1183

 Score = 28.5 bits (62), Expect = 5.3
 Identities = 18/40 (45%), Positives = 20/40 (50%), Gaps = 2/40 (5%)

Query: 8   TQSHSISSSSFGAEPSAP--GGGGSPGACPALGTKSCSSS 45
           T S  I  S+  A PSAP   GG S GA P  G    S+S
Sbjct: 596 TPSEKIEGSNGAATPSAPCGSGGRSSGATPVSGPPPPSAS 635


>gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens]
          Length = 904

 Score = 28.5 bits (62), Expect = 5.3
 Identities = 19/52 (36%), Positives = 26/52 (50%), Gaps = 2/52 (3%)

Query: 5   SAATQSH-SISSSSFGAEPSAPGGGGSPG-ACPALGTKSCSSSCAVHDLIFW 54
           +AA  SH ++  S+    P+ P GGG+P  A P     S S+S A  D   W
Sbjct: 355 TAAAASHPAVPPSAPDPRPATPQGGGAPRVAAPQTTLSSSSTSAATVDPPAW 406


>gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens]
          Length = 796

 Score = 28.5 bits (62), Expect = 5.3
 Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 4/51 (7%)

Query: 20  AEPSAPGG----GGSPGACPALGTKSCSSSCAVHDLIFWRDVKKTGFVFGT 66
           A P APGG    GG+PG      + S S+S +V ++      K+ G V  T
Sbjct: 288 APPGAPGGPACLGGTPGVSATSSSASSSTSSSVAEVGVGAGGKRPGSVSST 338


>gi|45827800 prestin isoform b [Homo sapiens]
          Length = 685

 Score = 28.1 bits (61), Expect = 6.9
 Identities = 17/73 (23%), Positives = 37/73 (50%), Gaps = 8/73 (10%)

Query: 163 KLAVFMWLMTYVGAVFNGITLLILAELLIFSVPIVYEKYKTQIDHYVGIARDQTKSIVEK 222
           K+ + +WL T+V ++F G+   ++  ++I  + ++   Y+TQ   Y  + +     +   
Sbjct: 466 KIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVI---YRTQSPSYKVLGKLPETDVYID 522

Query: 223 IQA-----KLPGI 230
           I A     ++PGI
Sbjct: 523 IDAYEEVKEIPGI 535


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.135    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,862,910
Number of Sequences: 37866
Number of extensions: 312437
Number of successful extensions: 2312
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 2271
Number of HSP's gapped (non-prelim): 51
length of query: 236
length of database: 18,247,518
effective HSP length: 99
effective length of query: 137
effective length of database: 14,498,784
effective search space: 1986333408
effective search space used: 1986333408
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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