Search of human proteins with 5174497

Search of human proteins with 5174497

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5174497 endothelial lipase precursor [Homo sapiens]
         (500 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5174497 endothelial lipase precursor [Homo sapiens]               1048   0.0  
gi|4557727 lipoprotein lipase precursor [Homo sapiens]                446   e-125
gi|194097335 lipase C precursor [Homo sapiens]                        405   e-113
gi|10835000 pancreatic lipase precursor [Homo sapiens]                197   2e-50
gi|5453920 pancreatic lipase-related protein 1 [Homo sapiens]         192   8e-49
gi|106507261 pancreatic lipase-related protein 2 [Homo sapiens]       191   1e-48
gi|39752679 lipase, member I [Homo sapiens]                           184   2e-46
gi|190341077 pancreatic lipase-related protein 3 [Homo sapiens]       183   4e-46
gi|21245106 lipase, member H precursor [Homo sapiens]                 181   1e-45
gi|7706661 phospholipase A1 member A [Homo sapiens]                   172   6e-43
gi|5174633 receptor for egg jelly-like protein precursor [Homo s...    34   0.27 
gi|19923084 polycystin-1L1 [Homo sapiens]                              33   0.60 
gi|150378549 tangerin [Homo sapiens]                                   33   0.79 
gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sap...    32   1.3  
gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]    30   3.9  
gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]      30   3.9  
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]    30   5.1  
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]     30   5.1  
gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]      30   5.1  
gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens]      30   5.1  
gi|7706625 retinoic acid receptor, beta isoform 2 [Homo sapiens]       30   5.1  

>gi|5174497 endothelial lipase precursor [Homo sapiens]
          Length = 500

 Score = 1048 bits (2709), Expect = 0.0
 Identities = 500/500 (100%), Positives = 500/500 (100%)

Query: 1   MSNSVPLLCFWSLCYCFAAGSPVPFGPEGRLEDKLHKPKATQTEVKPSVRFNLRTSKDPE 60
           MSNSVPLLCFWSLCYCFAAGSPVPFGPEGRLEDKLHKPKATQTEVKPSVRFNLRTSKDPE
Sbjct: 1   MSNSVPLLCFWSLCYCFAAGSPVPFGPEGRLEDKLHKPKATQTEVKPSVRFNLRTSKDPE 60

Query: 61  HEGCYLSVGHSQPLEDCSFNMTAKTFFIIHGWTMSGIFENWLHKLVSALHTREKDANVVV 120
           HEGCYLSVGHSQPLEDCSFNMTAKTFFIIHGWTMSGIFENWLHKLVSALHTREKDANVVV
Sbjct: 61  HEGCYLSVGHSQPLEDCSFNMTAKTFFIIHGWTMSGIFENWLHKLVSALHTREKDANVVV 120

Query: 121 VDWLPLAHQLYTDAVNNTRVVGHSIARMLDWLQEKDDFSLGNVHLIGYSLGAHVAGYAGN 180
           VDWLPLAHQLYTDAVNNTRVVGHSIARMLDWLQEKDDFSLGNVHLIGYSLGAHVAGYAGN
Sbjct: 121 VDWLPLAHQLYTDAVNNTRVVGHSIARMLDWLQEKDDFSLGNVHLIGYSLGAHVAGYAGN 180

Query: 181 FVKGTVGRITGLDPAGPMFEGADIHKRLSPDDADFVDVLHTYTRSFGLSIGIQMPVGHID 240
           FVKGTVGRITGLDPAGPMFEGADIHKRLSPDDADFVDVLHTYTRSFGLSIGIQMPVGHID
Sbjct: 181 FVKGTVGRITGLDPAGPMFEGADIHKRLSPDDADFVDVLHTYTRSFGLSIGIQMPVGHID 240

Query: 241 IYPNGGDFQPGCGLNDVLGSIAYGTITEVVKCEHERAVHLFVDSLVNQDKPSFAFQCTDS 300
           IYPNGGDFQPGCGLNDVLGSIAYGTITEVVKCEHERAVHLFVDSLVNQDKPSFAFQCTDS
Sbjct: 241 IYPNGGDFQPGCGLNDVLGSIAYGTITEVVKCEHERAVHLFVDSLVNQDKPSFAFQCTDS 300

Query: 301 NRFKKGICLSCRKNRCNSIGYNAKKMRNKRNSKMYLKTRAGMPFRVYHYQMKIHVFSYKN 360
           NRFKKGICLSCRKNRCNSIGYNAKKMRNKRNSKMYLKTRAGMPFRVYHYQMKIHVFSYKN
Sbjct: 301 NRFKKGICLSCRKNRCNSIGYNAKKMRNKRNSKMYLKTRAGMPFRVYHYQMKIHVFSYKN 360

Query: 361 MGEIEPTFYVTLYGTNADSQTLPLEIVERIEQNATNTFLVYTEEDLGDLLKIQLTWEGAS 420
           MGEIEPTFYVTLYGTNADSQTLPLEIVERIEQNATNTFLVYTEEDLGDLLKIQLTWEGAS
Sbjct: 361 MGEIEPTFYVTLYGTNADSQTLPLEIVERIEQNATNTFLVYTEEDLGDLLKIQLTWEGAS 420

Query: 421 QSWYNLWKEFRSYLSQPRNPGRELNIRRIRVKSGETQRKLTFCTEDPENTSISPGRELWF 480
           QSWYNLWKEFRSYLSQPRNPGRELNIRRIRVKSGETQRKLTFCTEDPENTSISPGRELWF
Sbjct: 421 QSWYNLWKEFRSYLSQPRNPGRELNIRRIRVKSGETQRKLTFCTEDPENTSISPGRELWF 480

Query: 481 RKCRDGWRMKNETSPTVELP 500
           RKCRDGWRMKNETSPTVELP
Sbjct: 481 RKCRDGWRMKNETSPTVELP 500


>gi|4557727 lipoprotein lipase precursor [Homo sapiens]
          Length = 475

 Score =  446 bits (1146), Expect = e-125
 Identities = 216/441 (48%), Positives = 305/441 (69%), Gaps = 18/441 (4%)

Query: 50  RFNLRTSKDPEHEGCYLSVGHSQPLEDCSFNMTAKTFFIIHGWTMSGIFENWLHKLVSAL 109
           +F LRT +D   + C+L  G ++ +  C FN ++KTF +IHGWT++G++E+W+ KLV+AL
Sbjct: 40  KFALRTPEDTAEDTCHLIPGVAESVATCHFNHSSKTFMVIHGWTVTGMYESWVPKLVAAL 99

Query: 110 HTREKDANVVVVDWLPLAHQLYTDAVNNTRVVGHSIARMLDWLQEKDDFSLGNVHLIGYS 169
           + RE D+NV+VVDWL  A + Y  +   T++VG  +AR ++W++E+ ++ L NVHL+GYS
Sbjct: 100 YKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHLLGYS 159

Query: 170 LGAHVAGYAGNFVKGTVGRITGLDPAGPMFEGADIHKRLSPDDADFVDVLHTYTR-SFGL 228
           LGAH AG AG+     V RITGLDPAGP FE A+   RLSPDDADFVDVLHT+TR S G 
Sbjct: 160 LGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGR 219

Query: 229 SIGIQMPVGHIDIYPNGGDFQPGCGLNDVLGSIA---YGTITEVVKCEHERAVHLFVDSL 285
           SIGIQ PVGH+DIYPNGG FQPGC + + +  IA    G + ++VKC HER++HLF+DSL
Sbjct: 220 SIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSL 279

Query: 286 VNQDKPSFAFQCTDSNRFKKGICLSCRKNRCNSIGYNAKKMRNKRNSKMYLKTRAGMPFR 345
           +N++ PS A++C+    F+KG+CLSCRKNRCN++GY   K+R KR+SKMYLKTR+ MP++
Sbjct: 280 LNEENPSKAYRCSSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYK 339

Query: 346 VYHYQMKIHVFSYKNMGEIEPTFYVTLYGTNADSQTLPLEIVERIEQNATNTFLVYTEED 405
           V+HYQ+KIH    ++       F ++LYGT A+S+ +P  + E +  N T +FL+YTE D
Sbjct: 340 VFHYQVKIHFSGTESETHTNQAFEISLYGTVAESENIPFTLPE-VSTNKTYSFLIYTEVD 398

Query: 406 LGDLLKIQLTWEGASQ-SWYNLWKEFRSYLSQPRNPGRELNIRRIRVKSGETQRKLTFCT 464
           +G+LL ++L W+  S  SW + W           +PG    I++IRVK+GETQ+K+ FC+
Sbjct: 399 IGELLMLKLKWKSDSYFSWSDWWS----------SPG--FAIQKIRVKAGETQKKVIFCS 446

Query: 465 EDPENTSISPGRELWFRKCRD 485
            +  +          F KC D
Sbjct: 447 REKVSHLQKGKAPAVFVKCHD 467


>gi|194097335 lipase C precursor [Homo sapiens]
          Length = 499

 Score =  405 bits (1040), Expect = e-113
 Identities = 199/444 (44%), Positives = 296/444 (66%), Gaps = 18/444 (4%)

Query: 61  HEGCYLSVGHSQPLEDCSFNMTAKTFFIIHGWTMSGIFENWLHKLVSALHTRE-KDANVV 119
           ++GC + + H   L++C FN +     IIHGW++ G+ ENW+ ++V+AL ++  +  NV 
Sbjct: 59  NQGCQIRINHPDTLQECGFNSSLPLVMIIHGWSVDGVLENWIWQMVAALKSQPAQPVNVG 118

Query: 120 VVDWLPLAHQLYTDAVNNTRVVGHSIARMLDWLQEKDDFSLGNVHLIGYSLGAHVAGYAG 179
           +VDW+ LAH  YT AV NTR+VG  +A +L WL+E    S  +VHLIGYSLGAHV+G+AG
Sbjct: 119 LVDWITLAHDHYTIAVRNTRLVGKEVAALLRWLEESVQLSRSHVHLIGYSLGAHVSGFAG 178

Query: 180 NFVKGT--VGRITGLDPAGPMFEGADIHKRLSPDDADFVDVLHTYTRS-FGLSIGIQMPV 236
           + + GT  +GRITGLD AGP+FEG+    RLSPDDA+FVD +HT+TR   GLS+GI+ P+
Sbjct: 179 SSIGGTHKIGRITGLDAAGPLFEGSAPSNRLSPDDANFVDAIHTFTREHMGLSVGIKQPI 238

Query: 237 GHIDIYPNGGDFQPGCGLNDVLGSIA---YGTITEVVKCEHERAVHLFVDSLVNQDKPSF 293
           GH D YPNGG FQPGC   ++   IA   +  IT+ +KC HER+VHLF+DSL++    S 
Sbjct: 239 GHYDFYPNGGSFQPGCHFLELYRHIAQHGFNAITQTIKCSHERSVHLFIDSLLHAGTQSM 298

Query: 294 AFQCTDSNRFKKGICLSCRKNRCNSIGYNAKKMRNKRNSKMYLKTRAGMPFRVYHYQMKI 353
           A+ C D N F +G+CLSC+K RCN++GY+ ++    ++ +++L TRA  PF+VYHYQ KI
Sbjct: 299 AYPCGDMNSFSQGLCLSCKKGRCNTLGYHVRQEPRSKSKRLFLVTRAQSPFKVYHYQFKI 358

Query: 354 HVFSYKNMGEIEPTFYVTLYGTNADSQTLPLEIVERIEQNATNTFLVYTEEDLGDLLKIQ 413
             F  +    I+ TF ++L GT    Q +P+ + + I  N T +FL+  + D+G+L+ I+
Sbjct: 359 Q-FINQTETPIQTTFTMSLLGTKEKMQKIPITLGKGIASNKTYSFLITLDVDIGELIMIK 417

Query: 414 LTWEGASQSWYNLWKEFRSYL---SQPRNPGRELNIRRIRVKSGETQRKLTFCTEDPENT 470
             WE  S  W N+W   ++ +   + PR+ G  L ++ IRVK+GETQ+++TFC+E+ ++ 
Sbjct: 418 FKWEN-SAVWANVWDTVQTIIPWSTGPRHSG--LVLKTIRVKAGETQQRMTFCSENTDDL 474

Query: 471 SISPGRELWFRKCRDGWRMKNETS 494
            + P +E  F KC     +K++TS
Sbjct: 475 LLRPTQEKIFVKC----EIKSKTS 494


>gi|10835000 pancreatic lipase precursor [Homo sapiens]
          Length = 465

 Score =  197 bits (501), Expect = 2e-50
 Identities = 144/420 (34%), Positives = 201/420 (47%), Gaps = 35/420 (8%)

Query: 13  LCY----CFAAGSPVPFGPEGRLEDKLHKPKATQTEVKPSVRFNLRTSKDPEHEGCYLSV 68
           +CY    CF+  SP     E  L      PK   T      RF L T+++P +   +  V
Sbjct: 19  VCYERLGCFSDDSPWSGITERPLHILPWSPKDVNT------RFLLYTNENPNN---FQEV 69

Query: 69  G-HSQPLEDCSFNMTAKTFFIIHGWTMSGIFENWLHKLVSALHTREKDANVVVVDWLPLA 127
              S  +   +F    KT FIIHG+   G  ENWL  +   L   E   N + VDW   +
Sbjct: 70  AADSSSISGSNFKTNRKTRFIIHGFIDKGE-ENWLANVCKNLFKVES-VNCICVDWKGGS 127

Query: 128 HQLYTDAVNNTRVVGHSIARMLDWLQEKDDFSLGNVHLIGYSLGAHVAGYAGNFVKGTVG 187
              YT A  N R+VG  +A  +++LQ    +S  NVH+IG+SLGAH AG AG    GT+G
Sbjct: 128 RTGYTQASQNIRIVGAEVAYFVEFLQSAFGYSPSNVHVIGHSLGAHAAGEAGRRTNGTIG 187

Query: 188 RITGLDPAGPMFEGADIHKRLSPDDADFVDVLHTYTRSF--GLSIGIQMPVGHIDIYPNG 245
           RITGLDPA P F+G     RL P DA FVDV+HT        L  G+   VGH+D +PNG
Sbjct: 188 RITGLDPAEPCFQGTPELVRLDPSDAKFVDVIHTDGAPIVPNLGFGMSQVVGHLDFFPNG 247

Query: 246 GDFQPGCGLNDV-----LGSIAYGTITEVVKCEHERAVHLFVDSLVNQDKPSFA-FQCTD 299
           G   PGC  N +     +  I  GT  +   C H R+   + DS+VN D   FA F C  
Sbjct: 248 GVEMPGCKKNILSQIVDIDGIWEGT-RDFAACNHLRSYKYYTDSIVNPD--GFAGFPCAS 304

Query: 300 SNRFKKGICLSCRKNRCNSIGYNAKKMRNKRN---SKMYLKTRAGMPFRVYHYQMKIHVF 356
            N F    C  C    C  +G+ A +   K N    K YL T     F  + Y++ + + 
Sbjct: 305 YNVFTANKCFPCPSGGCPQMGHYADRYPGKTNDVGQKFYLDTGDASNFARWRYKVSVTLS 364

Query: 357 SYKNMGEIEPTFYVTLYGTNADSQTLPLEIVERIEQNATNTFLVYTEEDLGDLLKIQLTW 416
             K  G I     V+L+G   +S+   +     ++ ++T++    ++ D+GDL  ++  W
Sbjct: 365 GKKVTGHI----LVSLFGNKGNSKQYEI-FKGTLKPDSTHSNEFDSDVDVGDLQMVKFIW 419


>gi|5453920 pancreatic lipase-related protein 1 [Homo sapiens]
          Length = 467

 Score =  192 bits (487), Expect = 8e-49
 Identities = 137/431 (31%), Positives = 207/431 (48%), Gaps = 37/431 (8%)

Query: 46  KPSVRFNLRTSKDPEHEGCYLSVGHSQPLEDCSFNMTAKTFFIIHGWTMSGIFENWLHKL 105
           K   RF L T+++P +    L +     +E  +F M  KT FIIHG+   G  E+W+  +
Sbjct: 51  KIGTRFLLYTNENPNNFQILL-LSDPSTIEASNFQMDRKTRFIIHGFIDKGD-ESWVTDM 108

Query: 106 VSALHTREKDANVVVVDWLPLAHQLYTDAVNNTRVVGHSIARMLDWLQEKDDFSLGNVHL 165
              L   E + N + VDW   +   YT A NN RVVG  +A+MLD L  +  +    VHL
Sbjct: 109 CKKLFEVE-EVNCICVDWKKGSQATYTQAANNVRVVGAQVAQMLDILLTEYSYPPSKVHL 167

Query: 166 IGYSLGAHVAGYAGNFVKGTVGRITGLDPAGPMFEGADIHKRLSPDDADFVDVLHTYTRS 225
           IG+SLGAHVAG AG+   G + RITGLDP    FE      RL P DADFVDV+HT    
Sbjct: 168 IGHSLGAHVAGEAGSKTPG-LSRITGLDPVEASFESTPEEVRLDPSDADFVDVIHTDAAP 226

Query: 226 F--GLSIGIQMPVGHIDIYPNGGDFQPGCGLNDV-----LGSIAYGTITEVVKCEHERAV 278
               L  G    +GH+D +PNGG+  PGC  N +     L  I  GT  + V C H R+ 
Sbjct: 227 LIPFLGFGTNQQMGHLDFFPNGGESMPGCKKNALSQIVDLDGIWAGT-RDFVACNHLRSY 285

Query: 279 HLFVDSLVNQDKPSFAFQCTDSNRFKKGICLSCRKNRCNSIGYNAKKM---RNKRNSKMY 335
             +++S++N D  + A+ CT    F+   C  C    C  +G+ A K     ++   K +
Sbjct: 286 KYYLESILNPDGFA-AYPCTSYKSFESDKCFPCPDQGCPQMGHYADKFAGRTSEEQQKFF 344

Query: 336 LKTRAGMPFRVYHYQMKIHVFSYKNMGEIEPTFYVTLYGTNADSQTLPLEIVERIEQNAT 395
           L T     F  + Y + I +      G+I+    V L+G   ++    +     ++  +T
Sbjct: 345 LNTGEASNFARWRYGVSITLSGRTATGQIK----VALFGNKGNTHQYSI-FRGILKPGST 399

Query: 396 NTFLVYTEEDLGDLLKIQLTWEGASQSWYNLWKEFRSYLSQPRNPGRELNIRRIRVKSGE 455
           +++    + D+G + K++  W               + +  P  P  ++   +I V+ GE
Sbjct: 400 HSYEFDAKLDVGTIEKVKFLW--------------NNNVINPTLP--KVGATKITVQKGE 443

Query: 456 TQRKLTFCTED 466
            +    FC+ED
Sbjct: 444 EKTVYNFCSED 454


>gi|106507261 pancreatic lipase-related protein 2 [Homo sapiens]
          Length = 470

 Score =  191 bits (486), Expect = 1e-48
 Identities = 132/429 (30%), Positives = 214/429 (49%), Gaps = 39/429 (9%)

Query: 50  RFNLRTSKDPEHEGCYLSVGHSQP--LEDCSFNMTAKTFFIIHGWTMSGIFENWLHKLVS 107
           RF L T+++P +   +  +  ++P  +E  +F +  KT FIIHG+ +    ++W   +  
Sbjct: 56  RFLLYTNENPNN---FQLITGTEPDTIEASNFQLDRKTRFIIHGF-LDKAEDSWPSDMCK 111

Query: 108 ALHTREKDANVVVVDWLPLAHQLYTDAVNNTRVVGHSIARMLDWLQEKDDFSLGNVHLIG 167
            +   EK  N + VDW   +  +YT AV N RVVG   A ++  L  +  +SL +VH+IG
Sbjct: 112 KMFEVEK-VNCICVDWRHGSRAMYTQAVQNIRVVGAETAFLIQALSTQLGYSLEDVHVIG 170

Query: 168 YSLGAHVAGYAGNFVKGTVGRITGLDPAGPMFEGADIHKRLSPDDADFVDVLHTYTRSF- 226
           +SLGAH A  AG  + G VGRITGLDPAGP F+      RL P DA FVDV+HT +    
Sbjct: 171 HSLGAHTAAEAGRRLGGRVGRITGLDPAGPCFQDEPEEVRLDPSDAVFVDVIHTDSSPIV 230

Query: 227 -GLSIGIQMPVGHIDIYPNGGDFQPGCGLNDVLGSIA-----YGTITEVVKCEHERAVHL 280
             L  G+   VGH+D +PNGG   PGC  N VL +I      +  I   V C H R+   
Sbjct: 231 PSLGFGMSQKVGHLDFFPNGGKEMPGCKKN-VLSTITDIDGIWEGIGGFVSCNHLRSFEY 289

Query: 281 FVDSLVNQDKPSFAFQCTDSNRFKKGICLSCRKNRCNSIGYNAKKMRNKRNS---KMYLK 337
           +  S++N D     + C   + F++  C  C    C  +G+ A + + K ++     +L 
Sbjct: 290 YSSSVLNPD-GFLGYPCASYDEFQESKCFPCPAEGCPKMGHYADQFKGKTSAVEQTFFLN 348

Query: 338 TRAGMPFRVYHYQMKIHVFSYKNMGEIEPTFYVTLYGTNADSQTLPLEIVERIEQNATNT 397
           T     F  + Y++ +   +     ++     + LYG+N +S+   +     ++ +A++T
Sbjct: 349 TGESGNFTSWRYKVSV---TLSGKEKVNGYIRIALYGSNENSKQYEI-FKGSLKPDASHT 404

Query: 398 FLVYTEEDLGDLLKIQLTWEGASQSWYNLWKEFRSYLSQPRNPGRELNIRRIRVKSGETQ 457
             +  + ++G + K++            LW +    LS+P+     L   +I V+SGE  
Sbjct: 405 CAIDVDFNVGKIQKVKF-----------LWNKRGINLSEPK-----LGASQITVQSGEDG 448

Query: 458 RKLTFCTED 466
            +  FC+ D
Sbjct: 449 TEYNFCSSD 457


>gi|39752679 lipase, member I [Homo sapiens]
          Length = 481

 Score =  184 bits (467), Expect = 2e-46
 Identities = 119/318 (37%), Positives = 163/318 (51%), Gaps = 40/318 (12%)

Query: 78  SFNMTAKTFFIIHGWTMSGIFENWLHKLVSALHTREKDANVVVVDWLPLAHQ-LYTDAVN 136
           +FN   KT ++IHG+   G    WL   V  L   E+D NV+VVDW   A   +Y  AV 
Sbjct: 90  NFNTQKKTVWLIHGYRPVGSIPLWLQNFVRIL-LNEEDMNVIVVDWSRGATTFIYNRAVK 148

Query: 137 NTRVVGHSIARMLDWLQEKDDFSLGNVHLIGYSLGAHVAGYAGNFVKGTVGRITGLDPAG 196
           NTR V  S++  +  L  K   SL N H IG SLGAH++G+ G    G +GRITGLDPAG
Sbjct: 149 NTRKVAVSLSVHIKNLL-KHGASLDNFHFIGVSLGAHISGFVGKIFHGQLGRITGLDPAG 207

Query: 197 PMFEGADIHKRLSPDDADFVDVLHTYTRSFGLSIGIQMPVGHIDIYPNGGDFQPGCGLND 256
           P F     + RL   DA FVDV+H+ +      +GIQ P+GHID YPNGG+ QPGC  + 
Sbjct: 208 PRFSRKPPYSRLDYTDAKFVDVIHSDSN----GLGIQEPLGHIDFYPNGGNKQPGCPKSI 263

Query: 257 VLGSIAYGTITEVVKCEHERAVHLFVDSLVNQDKPSFAFQCTDSNRFKKGICLSC---RK 313
             G        + +KC H+RAVHLF+ SL   +    +F C     +K  +C+ C   ++
Sbjct: 264 FSG-------IQFIKCNHQRAVHLFMASL-ETNCNFISFPCRSYKDYKTSLCVDCDCFKE 315

Query: 314 NRCNSIGYNAKKMRNKRNSKM---------YLKTRAGMPFRVYHYQMKIHV--------- 355
             C  +GY AK  +     +M         +L T    PF  Y++ + I V         
Sbjct: 316 KSCPRLGYQAKLFKGVLKERMEGRPLRTTVFLDTSGTYPFCTYYFVLSIIVPDKTMMDGS 375

Query: 356 FSYKNMGEI----EPTFY 369
           FS+K + ++    EP  Y
Sbjct: 376 FSFKLLNQLGMIEEPRLY 393


>gi|190341077 pancreatic lipase-related protein 3 [Homo sapiens]
          Length = 467

 Score =  183 bits (464), Expect = 4e-46
 Identities = 152/485 (31%), Positives = 225/485 (46%), Gaps = 56/485 (11%)

Query: 7   LLCFWSLCYCF---AAGSPVPFGPEGRLEDKLHKPKATQTEV--------KPSVRFNLRT 55
           +L  W + + F   + G  V +   G  +D L   +   TE+        K + RF L T
Sbjct: 1   MLGIWIVAFLFFGTSRGKEVCYERLGCFKDGLPWTRTFSTELVGLPWSPEKINTRFLLYT 60

Query: 56  SKDPEHEGCYLSVGHSQPLEDCSFNMTAKTFFIIHGWTMSGIFENWLHKLVSALHTREKD 115
             +P      +S  +S  ++   F     T   I GW   G    W   + + L   E D
Sbjct: 61  IHNPNAYQ-EISAVNSSTIQASYFGTDKITRINIAGWKTDG---KWQRDMCNVLLQLE-D 115

Query: 116 ANVVVVDWLPLAHQLYTDAVNNTRVVGHSIARMLDWLQEKDDFSLGNVHLIGYSLGAHVA 175
            N + +DW+  + + Y  AVNN RVVG  +A  +D L +K ++S   VHLIG+SLGAH+A
Sbjct: 116 INCINLDWINGSRE-YIHAVNNLRVVGAEVAYFIDVLMKKFEYSPSKVHLIGHSLGAHLA 174

Query: 176 GYAGNFVKGTVGRITGLDPAGPMFEGADIHKRLSPDDADFVDVLHTYTRS--FGLSIGIQ 233
           G AG+ + G +GRITGLDPAGP F       RL P DA+FVDV+HT      F L +G  
Sbjct: 175 GEAGSRIPG-LGRITGLDPAGPFFHNTPKEVRLDPSDANFVDVIHTNAARILFELGVGTI 233

Query: 234 MPVGHIDIYPNGGDFQPGCGLNDVLGSI------AY-GTITEVVKCEHERAVHLFVDSLV 286
              GH+D YPNGG   PGC   D++  +      AY   +     C H R+   + +S++
Sbjct: 234 DACGHLDFYPNGGKHMPGC--EDLITPLLKFNFNAYKKEMASFFDCNHARSYQFYAESIL 291

Query: 287 NQDKPSFAFQCTDSNRFKKGICLSCRKNRCNSIGYNAKKMRNK----RNSKMYLKTRAGM 342
           N D    A+ C     FK G C  C K  C ++G+ A +   K      S  +L T +  
Sbjct: 292 NPD-AFIAYPCRSYTSFKAGNCFFCSKEGCPTMGHFADRFHFKNMKTNGSHYFLNTGSLS 350

Query: 343 PFRVYHYQMKIHVFSYKNMGEIEPTFYVTLYGTNADSQTLPLEIVE-RIEQNATNTFLVY 401
           PF  +      H  S K  G       V L    A  +T    IV  ++E   T T L+ 
Sbjct: 351 PFARWR-----HKLSVKLSGSEVTQGTVFLRVGGAVRKTGEFAIVSGKLEPGMTYTKLID 405

Query: 402 TEEDLGDLLKIQLTWEGASQSWYNLWKEFRSYLSQPRNPGRELNIRRIRVKSGETQRKLT 461
            + ++G++  +Q  W+       +L+++ ++ L      G E+ I      SG+   K T
Sbjct: 406 ADVNVGNITSVQFIWK------KHLFEDSQNKL------GAEMVIN----TSGKYGYKST 449

Query: 462 FCTED 466
           FC++D
Sbjct: 450 FCSQD 454


>gi|21245106 lipase, member H precursor [Homo sapiens]
          Length = 451

 Score =  181 bits (460), Expect = 1e-45
 Identities = 111/286 (38%), Positives = 159/286 (55%), Gaps = 24/286 (8%)

Query: 78  SFNMTAKTFFIIHGWTMSGIFENWLHKLVSALHTREKDANVVVVDWLPLAHQL-YTDAVN 136
           + N+T KT FI+HG+  +G    W+  LV  L + E D NVVVVDW   A  L YT A +
Sbjct: 64  NLNVTKKTTFIVHGFRPTGSPPVWMDDLVKGLLSVE-DMNVVVVDWNRGATTLIYTHASS 122

Query: 137 NTRVVGHSIARMLDWLQEKDDFSLGNVHLIGYSLGAHVAGYAGNFVKGTVGRITGLDPAG 196
            TR V   +   +D +   +  SL ++++IG SLGAH++G+ G    G +GRITGLDPAG
Sbjct: 123 KTRKVAMVLKEFIDQMLA-EGASLDDIYMIGVSLGAHISGFVGEMYDGWLGRITGLDPAG 181

Query: 197 PMFEGADIHKRLSPDDADFVDVLHTYTRSFGLSIGIQMPVGHIDIYPNGGDFQPGCGLND 256
           P+F G     RL P DA FVDV+H+ T     ++G + P+G+ID YPNGG  QPGC    
Sbjct: 182 PLFNGKPHQDRLDPSDAQFVDVIHSDTD----ALGYKEPLGNIDFYPNGGLDQPGCP-KT 236

Query: 257 VLGSIAYGTITEVVKCEHERAVHLFVDSLVNQDKPSFAFQCTDSNRFKKGICLSC---RK 313
           +LG   Y       KC+H+R+V+L++ SL  +     A+ C     ++ G C+SC   +K
Sbjct: 237 ILGGFQY------FKCDHQRSVYLYLSSL-RESCTITAYPCDSYQDYRNGKCVSCGTSQK 289

Query: 314 NRCNSIGYNAKKMRNKRN------SKMYLKTRAGMPFRVYHYQMKI 353
             C  +GY A   ++         +K +  T    PF +YHY + I
Sbjct: 290 ESCPLLGYYADNWKDHLRGKDPPMTKAFFDTAEESPFCMYHYFVDI 335


>gi|7706661 phospholipase A1 member A [Homo sapiens]
          Length = 456

 Score =  172 bits (436), Expect = 6e-43
 Identities = 126/372 (33%), Positives = 182/372 (48%), Gaps = 31/372 (8%)

Query: 9   CFW--SLCYCFAAGSP--VPFGPEGRLEDKLHKPKATQTEVKPSVRFNLRTSKDPEHEGC 64
           CFW   L    + GS    P  P+ +  D         T++K  V+F L    +P    C
Sbjct: 9   CFWVGGLILWLSVGSSGDAPPTPQPKCADFQSANLFEGTDLK--VQFLLFVPSNPS---C 63

Query: 65  YLSVGHSQPLEDCSFNMTAKTFFIIHGWTMSGIFENWLHKLVSALHTREKDANVVVVDWL 124
              V  S  L++  FN T  T  IIHG+ + G   +W+   +  L  R  +ANV+ VDW+
Sbjct: 64  GQLVEGSSDLQNSGFNATLGTKLIIHGFRVLGTKPSWIDTFIRTL-LRATNANVIAVDWI 122

Query: 125 PLAHQLYTDAVNNTRVVGHSIARMLDWLQEKDDFSLGNVHLIGYSLGAHVAGYAGNFVKG 184
             +  +Y  AV N   +   I+  L+ L      S  ++H+IG SLGAHV G  G    G
Sbjct: 123 YGSTGVYFSAVKNVIKLSLEISLFLNKLLVLG-VSESSIHIIGVSLGAHVGGMVGQLFGG 181

Query: 185 TVGRITGLDPAGPMFEGADIHKRLSPDDADFVDVLHTYTRSFGLSIGIQMPVGHIDIYPN 244
            +G+ITGLDPAGP +  A + +RL   DA FV+ +HT T     ++GI++PVGH+D + N
Sbjct: 182 QLGQITGLDPAGPEYTRASVEERLDAGDALFVEAIHTDTD----NLGIRIPVGHVDYFVN 237

Query: 245 GGDFQPGCGLNDVLGSIAYGTITEVVKCEHERAVHLFVDSLVNQDKPSFAFQCTDSNRFK 304
           GG  QPGC       +  Y   + ++ C+H RAVHL++ +L N   P  AF C     F 
Sbjct: 238 GGQDQPGC------PTFFYAGYSYLI-CDHMRAVHLYISALEN-SCPLMAFPCASYKAFL 289

Query: 305 KGICLSCRKN---RCNSIGY----NAKKMRNKRNSKMYLKTRAGMPFRVYHYQMKIHVFS 357
            G CL C       C  IG       K     +  K+YL T +  P+ ++H  ++ H+  
Sbjct: 290 AGRCLDCFNPFLLSCPRIGLVEQGGVKIEPLPKEVKVYLLTTSSAPYCMHHSLVEFHLKE 349

Query: 358 YKNMG-EIEPTF 368
            +N    IE TF
Sbjct: 350 LRNKDTNIEVTF 361


>gi|5174633 receptor for egg jelly-like protein precursor [Homo
            sapiens]
          Length = 2253

 Score = 34.3 bits (77), Expect = 0.27
 Identities = 23/61 (37%), Positives = 33/61 (54%), Gaps = 6/61 (9%)

Query: 369  YVTLYGT--NADSQTLPLEIVERIEQNATNTFLVYTEEDLGDLLKIQLTW---EGASQSW 423
            +V L GT   +D   L       + + + NTFL+ T+ DLGD+  I++ W   EG S SW
Sbjct: 1251 FVQLRGTVSTSDVHCLSHPHFTTLYRGSINTFLLTTKSDLGDIHSIRV-WHNNEGRSPSW 1309

Query: 424  Y 424
            Y
Sbjct: 1310 Y 1310


>gi|19923084 polycystin-1L1 [Homo sapiens]
          Length = 2849

 Score = 33.1 bits (74), Expect = 0.60
 Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 6/61 (9%)

Query: 369  YVTLYGTNADSQTLPLEIVER--IEQNATNTFLVYTEEDLGDLLKIQLTW---EGASQSW 423
            Y+ L G N  S+T  L   E+   E+N+ +TF++     LG L KI+L W    G S  W
Sbjct: 1817 YIVLCGDNGLSETKELSCPEKPLFERNSRHTFILSAPAQLGLLRKIRL-WHDSRGPSPGW 1875

Query: 424  Y 424
            +
Sbjct: 1876 F 1876


>gi|150378549 tangerin [Homo sapiens]
          Length = 1523

 Score = 32.7 bits (73), Expect = 0.79
 Identities = 14/37 (37%), Positives = 21/37 (56%)

Query: 435 SQPRNPGRELNIRRIRVKSGETQRKLTFCTEDPENTS 471
           ++PR+ GRE N +R  V++GE +     C  D E  S
Sbjct: 394 TEPRSGGREANTKRSGVRAGEAEESSAVCQVDAEQRS 430


>gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo
           sapiens]
          Length = 2211

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 19/82 (23%), Positives = 38/82 (46%), Gaps = 3/82 (3%)

Query: 345 RVYHYQMKIHVFSYKNMGEIEPTFYVTLYGTNADSQTLPLEIVERIEQNATNTFLVYTEE 404
           ++ HY+++I        G      Y+ +YG    ++ L L    ++ + A+         
Sbjct: 812 KLVHYEVEIWTGDVGGAGT-SARVYMQIYGEKGKTEVLFLSSRSKVFERASKDTFQLEAA 870

Query: 405 DLGDLLKIQL--TWEGASQSWY 424
           D+G++ K++L  T EG   SW+
Sbjct: 871 DVGEVYKLRLGHTGEGFGPSWF 892



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 7/62 (11%)

Query: 369  YVTLYGTN-ADSQTLPLEIVER---IEQNATNTFLVYTEEDLGDLLKIQLTWE--GASQS 422
            Y+T+YG    D+   PL+  ++    EQ  T+TF +Y   DLG L KI++  +  G    
Sbjct: 1043 YLTIYGEEYGDTGERPLKKSDKSNKFEQGQTDTFTIYA-IDLGALTKIRIRHDNTGNRAG 1101

Query: 423  WY 424
            W+
Sbjct: 1102 WF 1103


>gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]
          Length = 443

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 13/43 (30%), Positives = 20/43 (46%)

Query: 301 NRFKKGICLSCRKNRCNSIGYNAKKMRNKRNSKMYLKTRAGMP 343
           N+  +  C  CR  +C  +G + + +RN RN K       G P
Sbjct: 124 NKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSP 166


>gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]
          Length = 454

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 13/43 (30%), Positives = 20/43 (46%)

Query: 301 NRFKKGICLSCRKNRCNSIGYNAKKMRNKRNSKMYLKTRAGMP 343
           N+  +  C  CR  +C  +G + + +RN RN K       G P
Sbjct: 135 NKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSP 177


>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
          Length = 462

 Score = 30.0 bits (66), Expect = 5.1
 Identities = 11/33 (33%), Positives = 18/33 (54%)

Query: 301 NRFKKGICLSCRKNRCNSIGYNAKKMRNKRNSK 333
           N+  +  C  CR  +C  +G + + +RN RN K
Sbjct: 133 NKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKK 165


>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
          Length = 457

 Score = 30.0 bits (66), Expect = 5.1
 Identities = 11/33 (33%), Positives = 18/33 (54%)

Query: 301 NRFKKGICLSCRKNRCNSIGYNAKKMRNKRNSK 333
           N+  +  C  CR  +C  +G + + +RN RN K
Sbjct: 128 NKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKK 160


>gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
          Length = 462

 Score = 30.0 bits (66), Expect = 5.1
 Identities = 11/33 (33%), Positives = 18/33 (54%)

Query: 301 NRFKKGICLSCRKNRCNSIGYNAKKMRNKRNSK 333
           N+  +  C  CR  +C  +G + + +RN RN K
Sbjct: 133 NKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKK 165


>gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens]
          Length = 448

 Score = 30.0 bits (66), Expect = 5.1
 Identities = 11/33 (33%), Positives = 18/33 (54%)

Query: 301 NRFKKGICLSCRKNRCNSIGYNAKKMRNKRNSK 333
           N+  +  C  CR  +C  +G + + +RN RN K
Sbjct: 126 NKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKK 158


>gi|7706625 retinoic acid receptor, beta isoform 2 [Homo sapiens]
          Length = 336

 Score = 30.0 bits (66), Expect = 5.1
 Identities = 11/33 (33%), Positives = 18/33 (54%)

Query: 301 NRFKKGICLSCRKNRCNSIGYNAKKMRNKRNSK 333
           N+  +  C  CR  +C  +G + + +RN RN K
Sbjct: 14  NKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKK 46


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,491,678
Number of Sequences: 37866
Number of extensions: 945694
Number of successful extensions: 1877
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1814
Number of HSP's gapped (non-prelim): 26
length of query: 500
length of database: 18,247,518
effective HSP length: 106
effective length of query: 394
effective length of database: 14,233,722
effective search space: 5608086468
effective search space used: 5608086468
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.