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Search of human proteins with 51593088
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|51593088 neuroligin 3 [Homo sapiens]
(828 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|51593088 neuroligin 3 [Homo sapiens] 1718 0.0
gi|31317256 X-linked neuroligin 4 [Homo sapiens] 1231 0.0
gi|24308209 X-linked neuroligin 4 [Homo sapiens] 1231 0.0
gi|40538788 neuroligin 4, Y-linked [Homo sapiens] 1212 0.0
gi|7662470 neuroligin 1 [Homo sapiens] 1120 0.0
gi|30840978 neuroligin 2 [Homo sapiens] 1056 0.0
gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo sa... 323 4e-88
gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo sa... 322 9e-88
gi|4557351 butyrylcholinesterase precursor [Homo sapiens] 306 4e-83
gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens] 292 8e-79
gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens] 292 8e-79
gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens] 292 1e-78
gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens] 288 1e-77
gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens] 287 3e-77
gi|148536848 carboxyl ester lipase precursor [Homo sapiens] 286 7e-77
gi|33563374 carboxylesterase 3 [Homo sapiens] 285 1e-76
gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens] 271 2e-72
gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens] 239 8e-63
gi|115529439 carboxylesterase 8 (putative) [Homo sapiens] 234 2e-61
gi|55770862 thyroglobulin [Homo sapiens] 193 5e-49
gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens] 150 5e-36
gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens] 150 5e-36
gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens] 92 2e-18
gi|18079216 CASK interacting protein 1 [Homo sapiens] 33 0.83
gi|115430245 arylhydrocarbon receptor repressor [Homo sapiens] 33 0.83
gi|5729962 submaxillary gland androgen regulated protein 3 homol... 33 1.1
gi|116284392 mucin 2 precursor [Homo sapiens] 32 3.2
gi|88758613 CD93 antigen precursor [Homo sapiens] 32 3.2
gi|73695473 roquin [Homo sapiens] 32 3.2
gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo ... 31 4.1
>gi|51593088 neuroligin 3 [Homo sapiens]
Length = 828
Score = 1718 bits (4450), Expect = 0.0
Identities = 828/828 (100%), Positives = 828/828 (100%)
Query: 1 MWLRLGPPSLSLSPKPTVGRSLCLTLWFLSLALRASTQAPAPTVNTHFGKLRGARVPLPS 60
MWLRLGPPSLSLSPKPTVGRSLCLTLWFLSLALRASTQAPAPTVNTHFGKLRGARVPLPS
Sbjct: 1 MWLRLGPPSLSLSPKPTVGRSLCLTLWFLSLALRASTQAPAPTVNTHFGKLRGARVPLPS 60
Query: 61 EILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLP 120
EILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLP
Sbjct: 61 EILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLP 120
Query: 121 VWFTANLDIVATYIQEPNEDCLYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAK 180
VWFTANLDIVATYIQEPNEDCLYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAK
Sbjct: 121 VWFTANLDIVATYIQEPNEDCLYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAK 180
Query: 181 PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLD 240
PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLD
Sbjct: 181 PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLD 240
Query: 241 QIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSS 300
QIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSS
Sbjct: 241 QIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSS 300
Query: 301 WAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDG 360
WAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDG
Sbjct: 301 WAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDG 360
Query: 361 DVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNL 420
DVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNL
Sbjct: 361 DVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNL 420
Query: 421 YGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSP 480
YGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSP
Sbjct: 421 YGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSP 480
Query: 481 TYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTY 540
TYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTY
Sbjct: 481 TYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTY 540
Query: 541 WTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATK 600
WTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATK
Sbjct: 541 WTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATK 600
Query: 601 VAFWKHLVPHLYNLHDMFHYTSTTTKVPPPDTTHSSHITRRPNGKTWSTKRPAISPAYSN 660
VAFWKHLVPHLYNLHDMFHYTSTTTKVPPPDTTHSSHITRRPNGKTWSTKRPAISPAYSN
Sbjct: 601 VAFWKHLVPHLYNLHDMFHYTSTTTKVPPPDTTHSSHITRRPNGKTWSTKRPAISPAYSN 660
Query: 661 ENAQGSWNGDQDAGPLLVENPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEP 720
ENAQGSWNGDQDAGPLLVENPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEP
Sbjct: 661 ENAQGSWNGDQDAGPLLVENPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEP 720
Query: 721 LRQPSPQRGAGAPELGAAPEEELAALQLGPTHHECEAGPPHDTLRLTALPDYTLTLRRSP 780
LRQPSPQRGAGAPELGAAPEEELAALQLGPTHHECEAGPPHDTLRLTALPDYTLTLRRSP
Sbjct: 721 LRQPSPQRGAGAPELGAAPEEELAALQLGPTHHECEAGPPHDTLRLTALPDYTLTLRRSP 780
Query: 781 DDIPLMTPNTITMIPNSLVGLQTLHPYNTFAAGFNSTGLPHSHSTTRV 828
DDIPLMTPNTITMIPNSLVGLQTLHPYNTFAAGFNSTGLPHSHSTTRV
Sbjct: 781 DDIPLMTPNTITMIPNSLVGLQTLHPYNTFAAGFNSTGLPHSHSTTRV 828
>gi|31317256 X-linked neuroligin 4 [Homo sapiens]
Length = 816
Score = 1231 bits (3186), Expect = 0.0
Identities = 594/811 (73%), Positives = 680/811 (83%), Gaps = 29/811 (3%)
Query: 26 LWFLSLALRAS---TQAPAPTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEK 82
LW +LA++ + +QA P VNT++GK+RG R PLP+EILGPV+QYLGVPYA+PP GE+
Sbjct: 27 LWLTALAIKFTLIDSQAQYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGER 86
Query: 83 RFLPPEPPPSWSGIRNATHFPPVCPQNI-HTAVPEVMLPVWFTANLDIVATYIQEPNEDC 141
RF PPEPP SW+GIRN T F VCPQ++ ++ MLP+WFTANLD + TY+Q+ NEDC
Sbjct: 87 RFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDC 146
Query: 142 LYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAK-PVMVYIHGGSYMEGTGNMID 200
LYLN+YVPTED DI D +K PVMVYIHGGSYMEGTGNMID
Sbjct: 147 LYLNIYVPTED--------------------DIHDQNSKKPVMVYIHGGSYMEGTGNMID 186
Query: 201 GSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPR 260
GSILASYGNVIVIT+NYR+G+LGFLSTGDQAAKGNYGLLDQIQALRW+ EN+ FGGDP+
Sbjct: 187 GSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPK 246
Query: 261 RITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGC 320
R+T+FGSG GASCVSLLTLSH+SEGLFQ+AIIQSG+ALSSWAVNYQP KYT +LADKVGC
Sbjct: 247 RVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGC 306
Query: 321 NVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYD 380
N+LDT DMV+CLR K+ KEL++Q I PA YH+AFGPVIDGDVIPDDP+ILMEQGEFLNYD
Sbjct: 307 NMLDTTDMVECLRNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYD 366
Query: 381 IMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTD 440
IMLGVNQGEGLKFV+G+VD EDGV+ DFD+SVSNFVDNLYGYPEGKDTLRETIKFMYTD
Sbjct: 367 IMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTD 426
Query: 441 WADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSLMKPAWSD 500
WAD++NPETRRKTLVALFTDHQWV P+V TADLHA+YGSPTYFYAFYHHCQS MKP+W+D
Sbjct: 427 WADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWAD 486
Query: 501 AAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKF 560
+AHGDEVPYVFG+PM+GPT+LF CNFSKNDVMLSAVVMTYWTNFAKTGDPN+PVPQDTKF
Sbjct: 487 SAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKF 546
Query: 561 IHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNLHDMFHY 620
IHTK NRFEEVAWSKYNP+DQLYLHIGLKPRVRDHYRATKVAFW LVPHL+NL+++F Y
Sbjct: 547 IHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNLNEIFQY 606
Query: 621 TSTTTKVPPPDTTHSSHITRRPNGKTW-STKRPAISPAYSNENAQGSWNGDQDAGPLLVE 679
STTTKVPPPD T + TRR K W +TKRPAI+PA + ++++ + +L+E
Sbjct: 607 VSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPEDTTVLIE 666
Query: 680 NPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGAGAPELGAAP 739
RDYSTELSVTIAVGASLLFLN+LAFAALYY+KDKRR E R+PSPQR ++
Sbjct: 667 TKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRRPSPQRNT-TNDIAHIQ 725
Query: 740 EEELAALQLGPTH--HECEAGPPHDTLRLTALPDYTLTLRRSPDDIPLMTPNTITMIPNS 797
EE+ +LQ+ HECE+ HDTLRLT PDYTLTLRRSPDDIPLMTPNTITMIPN+
Sbjct: 726 NEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPLMTPNTITMIPNT 785
Query: 798 LVGLQTLHPYNTFAAGFNSTGLPHSHSTTRV 828
L G+Q LH +NTF+ G NST LPH HSTTRV
Sbjct: 786 LTGMQPLHTFNTFSGGQNSTNLPHGHSTTRV 816
>gi|24308209 X-linked neuroligin 4 [Homo sapiens]
Length = 816
Score = 1231 bits (3186), Expect = 0.0
Identities = 594/811 (73%), Positives = 680/811 (83%), Gaps = 29/811 (3%)
Query: 26 LWFLSLALRAS---TQAPAPTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEK 82
LW +LA++ + +QA P VNT++GK+RG R PLP+EILGPV+QYLGVPYA+PP GE+
Sbjct: 27 LWLTALAIKFTLIDSQAQYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGER 86
Query: 83 RFLPPEPPPSWSGIRNATHFPPVCPQNI-HTAVPEVMLPVWFTANLDIVATYIQEPNEDC 141
RF PPEPP SW+GIRN T F VCPQ++ ++ MLP+WFTANLD + TY+Q+ NEDC
Sbjct: 87 RFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDC 146
Query: 142 LYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAK-PVMVYIHGGSYMEGTGNMID 200
LYLN+YVPTED DI D +K PVMVYIHGGSYMEGTGNMID
Sbjct: 147 LYLNIYVPTED--------------------DIHDQNSKKPVMVYIHGGSYMEGTGNMID 186
Query: 201 GSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPR 260
GSILASYGNVIVIT+NYR+G+LGFLSTGDQAAKGNYGLLDQIQALRW+ EN+ FGGDP+
Sbjct: 187 GSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPK 246
Query: 261 RITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGC 320
R+T+FGSG GASCVSLLTLSH+SEGLFQ+AIIQSG+ALSSWAVNYQP KYT +LADKVGC
Sbjct: 247 RVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGC 306
Query: 321 NVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYD 380
N+LDT DMV+CLR K+ KEL++Q I PA YH+AFGPVIDGDVIPDDP+ILMEQGEFLNYD
Sbjct: 307 NMLDTTDMVECLRNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYD 366
Query: 381 IMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTD 440
IMLGVNQGEGLKFV+G+VD EDGV+ DFD+SVSNFVDNLYGYPEGKDTLRETIKFMYTD
Sbjct: 367 IMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTD 426
Query: 441 WADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSLMKPAWSD 500
WAD++NPETRRKTLVALFTDHQWV P+V TADLHA+YGSPTYFYAFYHHCQS MKP+W+D
Sbjct: 427 WADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWAD 486
Query: 501 AAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKF 560
+AHGDEVPYVFG+PM+GPT+LF CNFSKNDVMLSAVVMTYWTNFAKTGDPN+PVPQDTKF
Sbjct: 487 SAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKF 546
Query: 561 IHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNLHDMFHY 620
IHTK NRFEEVAWSKYNP+DQLYLHIGLKPRVRDHYRATKVAFW LVPHL+NL+++F Y
Sbjct: 547 IHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNLNEIFQY 606
Query: 621 TSTTTKVPPPDTTHSSHITRRPNGKTW-STKRPAISPAYSNENAQGSWNGDQDAGPLLVE 679
STTTKVPPPD T + TRR K W +TKRPAI+PA + ++++ + +L+E
Sbjct: 607 VSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPEDTTVLIE 666
Query: 680 NPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGAGAPELGAAP 739
RDYSTELSVTIAVGASLLFLN+LAFAALYY+KDKRR E R+PSPQR ++
Sbjct: 667 TKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRRPSPQRNT-TNDIAHIQ 725
Query: 740 EEELAALQLGPTH--HECEAGPPHDTLRLTALPDYTLTLRRSPDDIPLMTPNTITMIPNS 797
EE+ +LQ+ HECE+ HDTLRLT PDYTLTLRRSPDDIPLMTPNTITMIPN+
Sbjct: 726 NEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPLMTPNTITMIPNT 785
Query: 798 LVGLQTLHPYNTFAAGFNSTGLPHSHSTTRV 828
L G+Q LH +NTF+ G NST LPH HSTTRV
Sbjct: 786 LTGMQPLHTFNTFSGGQNSTNLPHGHSTTRV 816
>gi|40538788 neuroligin 4, Y-linked [Homo sapiens]
Length = 816
Score = 1212 bits (3135), Expect = 0.0
Identities = 586/811 (72%), Positives = 674/811 (83%), Gaps = 29/811 (3%)
Query: 26 LWFLSLALRAS---TQAPAPTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEK 82
LW +LA++ + +QA P VNT++GK++G R PLPSEILGPV+QYLGVPYA+PP GE+
Sbjct: 27 LWITALAIKFTLIDSQAQYPVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGER 86
Query: 83 RFLPPEPPPSWSGIRNATHFPPVCPQNIHTA-VPEVMLPVWFTANLDIVATYIQEPNEDC 141
RF PPE P SW+GIRNAT F VCPQ++ + MLP+WFT +LD + TY+Q+ NEDC
Sbjct: 87 RFQPPESPSSWTGIRNATQFSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNEDC 146
Query: 142 LYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAK-PVMVYIHGGSYMEGTGNMID 200
LYLN+YVP ED DI + +K PVMVYIHGGSYMEGTGNMID
Sbjct: 147 LYLNIYVPMED--------------------DIHEQNSKKPVMVYIHGGSYMEGTGNMID 186
Query: 201 GSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPR 260
GSILASYGNVIVIT+N R+G+LGFLSTGDQAAKGNYGLLDQIQALRW+ EN+ FGGDP+
Sbjct: 187 GSILASYGNVIVITINCRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPK 246
Query: 261 RITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGC 320
R+T+FGSG GASCVSLLTLSH+SEGLFQ+AIIQSG+ALSSWAVNYQP KYT +LADKVGC
Sbjct: 247 RVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGC 306
Query: 321 NVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYD 380
N+LDT DMV+CL+ K+ KEL++Q I PA YH+AFGPVIDGDVIPDDP+ILMEQGEFLNYD
Sbjct: 307 NMLDTTDMVECLKNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYD 366
Query: 381 IMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTD 440
IMLGVNQGEGLKFV+G+VD EDGV+ DFD+SVSNFVDNLYGYPEGKDTLRETIKFMYTD
Sbjct: 367 IMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTD 426
Query: 441 WADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSLMKPAWSD 500
WAD++NPETRRKTLVALFTDHQWV P+V TADLHA+YGSPTYFYAFYHHCQS MKP+W+D
Sbjct: 427 WADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWAD 486
Query: 501 AAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKF 560
+AHGDEVPYVFG+PM+GPT+LF CNFSKNDVMLSAVVMTYWTNFAKTGDPN+PVPQDTKF
Sbjct: 487 SAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKF 546
Query: 561 IHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNLHDMFHY 620
IHTK NRFEEVAWSKYNP+DQLYLHIGLKPRVRDHYRATKVAFW LVPHL+NL+++F Y
Sbjct: 547 IHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNLNEIFQY 606
Query: 621 TSTTTKVPPPDTTHSSHITRRPNGKTW-STKRPAISPAYSNENAQGSWNGDQDAGPLLVE 679
STTTKVPPPD T + TRR K W +TKRPAI+PA + ++++ + +L+E
Sbjct: 607 VSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPEDTTVLIE 666
Query: 680 NPRDYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGAGAPELGAAP 739
RDYSTELSVTIAVGASLLFLN+LAFAALYY+KDKRR E R PSPQR ++
Sbjct: 667 TKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRHPSPQRNT-TNDITHIQ 725
Query: 740 EEELAALQLGPTH--HECEAGPPHDTLRLTALPDYTLTLRRSPDDIPLMTPNTITMIPNS 797
EE+ +LQ+ HECE+ HDTLRLT PDYTLTLRRSPDDIP MTPNTITMIPN+
Sbjct: 726 NEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPFMTPNTITMIPNT 785
Query: 798 LVGLQTLHPYNTFAAGFNSTGLPHSHSTTRV 828
L+G+Q LH + TF+ G NST LPH HSTTRV
Sbjct: 786 LMGMQPLHTFKTFSGGQNSTNLPHGHSTTRV 816
>gi|7662470 neuroligin 1 [Homo sapiens]
Length = 823
Score = 1120 bits (2898), Expect = 0.0
Identities = 563/806 (69%), Positives = 641/806 (79%), Gaps = 54/806 (6%)
Query: 42 PTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATH 101
P V T+FGK+RG + L +EILGPV Q+LGVPYAAPP GE+RF PPEPP WS IRNAT
Sbjct: 53 PLVATNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQ 112
Query: 102 FPPVCPQNIHTA-VPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDGSGAKKQG 160
F PVCPQNI +PEVMLPVWFT NLD+V++Y+Q+ +EDCLYLN+YVPTED
Sbjct: 113 FAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTED-------- 164
Query: 161 EDLADNDGDEDEDIRDSGA-KPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRV 219
DIRDSG KPVMVYIHGGSYMEGTGN+ DGS+LASYGNVIVIT+NYR+
Sbjct: 165 ------------DIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRL 212
Query: 220 GVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTL 279
GVLGFLSTGDQAAKGNYGLLD IQALRW SENI FFGGDP RITVFGSG G SCV+LLTL
Sbjct: 213 GVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTL 272
Query: 280 SHHSEG---------LFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVD 330
SH+SEG LFQRAI QSG+ALSSWAV++QP KY +LA KVGCNV DTV++V+
Sbjct: 273 SHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVE 332
Query: 331 CLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLGVNQGEG 390
CL++K KELV+QDIQPARYH+AFGPVIDGDVIPDDP+ILMEQGEFLNYDIMLGVNQGEG
Sbjct: 333 CLQKKPYKELVDQDIQPARYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEG 392
Query: 391 LKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETR 450
LKFVE +VD +DG+S +DFD++VSNFVDNLYGYPEGKD LRETIKFMYTDWADR NPETR
Sbjct: 393 LKFVENIVDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPETR 452
Query: 451 RKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSLMKPAWSDAAHGDEVPYV 510
RKTL+ALFTDHQWV P+V TADLH+ +GSPTYFYAFYHHCQ+ PAW+DAAHGDEVPYV
Sbjct: 453 RKTLLALFTDHQWVAPAVATADLHSNFGSPTYFYAFYHHCQTDQVPAWADAAHGDEVPYV 512
Query: 511 FGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEE 570
G+PM+GPT+LFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN+PVPQDTKFIHTK NRFEE
Sbjct: 513 LGIPMIGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEE 572
Query: 571 VAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNLHDMFHYTSTTTKVPPP 630
VAW++Y+ +DQLYLHIGLKPRV++HYRA KV W LVPHL+NL+D+ YTSTTTKVP
Sbjct: 573 VAWTRYSQKDQLYLHIGLKPRVKEHYRANKVNLWLELVPHLHNLNDISQYTSTTTKVP-- 630
Query: 631 DTTHSSHITRRPNGKTWSTKRPAISPAYSNENAQGSWNGDQDAGPLLVENPRDYSTELSV 690
S+ IT RP K A A ++ Q P V+ RDYSTELSV
Sbjct: 631 ----STDITFRPTRKNSVPVTSAFPTAKQDD-------PKQQPSPFSVDQ-RDYSTELSV 678
Query: 691 TIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGAGAPELGAAPEEELAALQLGP 750
TIAVGASLLFLN+LAFAALYY+KDKRR + R+ SPQR +L A EEE+ +LQ+
Sbjct: 679 TIAVGASLLFLNILAFAALYYKKDKRRHDVHRRCSPQR-TTTNDLTHAQEEEIMSLQMKH 737
Query: 751 T--HHECEAGPPHD-TLRLTALPDYTLTLRRSPDDIPLMTPNTITMIPNSLVGLQTLHPY 807
T HECE+ PH+ LR PDYTL +RRSPDD+PLMTPNTITMIPN++ G+Q LH +
Sbjct: 738 TDLDHECESIHPHEVVLRTACPPDYTLAMRRSPDDVPLMTPNTITMIPNTIPGIQPLHTF 797
Query: 808 NTFAAGFNST-----GLPHSHSTTRV 828
NTF G N+T PHSHSTTRV
Sbjct: 798 NTFTGGQNNTLPHPHPHPHSHSTTRV 823
>gi|30840978 neuroligin 2 [Homo sapiens]
Length = 835
Score = 1056 bits (2732), Expect = 0.0
Identities = 528/814 (64%), Positives = 627/814 (77%), Gaps = 47/814 (5%)
Query: 42 PTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATH 101
P VNT +G++RG R L +EILGPV Q+LGVPYA PP+G +RF PPE P SW G+RNAT
Sbjct: 42 PVVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATT 101
Query: 102 FPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDGSGAKKQGE 161
PP CPQN+H A+P +MLPVWFT NL+ ATY+Q +EDCLYLN+YVPTEDG KK+ E
Sbjct: 102 LPPACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDE 161
Query: 162 DLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGV 221
+ D DIRD G KPVM+++HGGSYMEGTGNM DGS+LA+YGNVIV TLNYR+GV
Sbjct: 162 ATLN---PPDTDIRDPGKKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGV 218
Query: 222 LGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSH 281
LGFLSTGDQAAKGNYGLLDQIQALRW+SENIA FGGDP RIT+FGSG GASCV+LL LSH
Sbjct: 219 LGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSH 278
Query: 282 HSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELV 341
HSEGLFQ+AI QSG+A+SSW+VNYQP+KYT LLA KVGC+ D+ + V+CLR+K ++ELV
Sbjct: 279 HSEGLFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSRELV 338
Query: 342 EQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPE 401
+QD+QPARYH+AFGPV+DGDV+PDDPEILM+QGEFLNYD+++GVNQGEGLKFVE + E
Sbjct: 339 DQDVQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAESE 398
Query: 402 DGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDH 461
DGVS + FD++VSNFVDNLYGYPEGKD LRETIKFMYTDWADRDN E RRKTL+ALFTDH
Sbjct: 399 DGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKTLLALFTDH 458
Query: 462 QWVEPSVVTADLHARYGSPTYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDL 521
QWV P+V TA LHA Y SP YFY FYHHCQ+ +P W+DAAHGDE+PYVFGVPMVG TDL
Sbjct: 459 QWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGVPMVGATDL 518
Query: 522 FPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQ 581
FPCNFSKNDVMLSAVVMTYWTNFAKTGDPN+PVPQDTKFIHTK NRFEEV WSK+N +++
Sbjct: 519 FPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVVWSKFNSKEK 578
Query: 582 LYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNLH-DMFHYTSTTTKVPPPDTTHSSHITR 640
YLHIGLKPRVRD+YRA KVAFW LVPHL+NLH ++F +TTT++PP +++
Sbjct: 579 QYLHIGLKPRVRDNYRANKVAFWLELVPHLHNLHTELF---TTTTRLPP----YATRWPP 631
Query: 641 RPNGKTWSTKRPAISPAYSNENAQGSWNGDQDAGPLLVE----NPRDYSTELSVTIAVGA 696
RP T+RP E + + GP + + RDYSTELSVT+AVGA
Sbjct: 632 RPPAGAPGTRRPPPPATLPPE-------PEPEPGPRAYDRFPGDSRDYSTELSVTVAVGA 684
Query: 697 SLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGAGA------PELGAA-----PEEELAA 745
SLLFLN+LAFAALYY++D+R++ R+ SP G+G+ P L AA PEEEL +
Sbjct: 685 SLLFLNILAFAALYYKRDRRQELRCRRLSPPGGSGSGVPGGGPLLPAAGRELPPEEELVS 744
Query: 746 LQLGPTHHECEAGPPHDTLRLTALPDYTLTLRRSPDDIPLMTPNTITMIPNSL-----VG 800
LQL P + LR PDYTL LRR+PDD+PL+ P +T++P+ L
Sbjct: 745 LQL--KRGGGVGADPAEALRPACPPDYTLALRRAPDDVPLLAPGALTLLPSGLGPPPPPP 802
Query: 801 LQTLHPYNTF------AAGFNSTGLPHSHSTTRV 828
+LHP+ F A N+T LPH HSTTRV
Sbjct: 803 PPSLHPFGPFPPPPPTATSHNNT-LPHPHSTTRV 835
>gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo
sapiens]
Length = 614
Score = 323 bits (828), Expect = 4e-88
Identities = 216/630 (34%), Positives = 304/630 (48%), Gaps = 77/630 (12%)
Query: 7 PPSLSLSPKPTVGRSLCLTLWFLSLALRASTQAPAPT-VNTHFGKLRGARVPLPSEILGP 65
PP L L L LW L + A + A V G+LRG R+ P GP
Sbjct: 3 PPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPG---GP 59
Query: 66 VDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTA 125
V +LG+P+A PP+G +RFLPPEP WSG+ +AT F VC Q + T P +
Sbjct: 60 VSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNP 119
Query: 126 NLDIVATYIQEPNEDCLYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVY 185
N +E +EDCLYLNV+ P R + PV+V+
Sbjct: 120 N--------RELSEDCLYLNVWTPYP-----------------------RPTSPTPVLVW 148
Query: 186 IHGGSYMEGTGNM--IDGSILASYGNVIVITLNYRVGVLGFLST-GDQAAKGNYGLLDQI 242
I+GG + G ++ DG L +++++NYRVG GFL+ G + A GN GLLDQ
Sbjct: 149 IYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQR 208
Query: 243 QALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWA 302
AL+WV EN+A FGGDP +T+FG GA+ V + LS S GLF RA++QSG+ WA
Sbjct: 209 LALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWA 268
Query: 303 V--NYQPVKYTSLLADKVGCNVLDT----VDMVDCLRQKSAKELVEQD----IQPARYHV 352
+ + + LA VGC T ++V CLR + A+ LV + Q + +
Sbjct: 269 TVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRF 328
Query: 353 AFGPVIDGDVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKF-VEGV----VDPEDGVSGT 407
+F PV+DGD + D PE L+ G+F +++GV + EG F V G D E +S
Sbjct: 329 SFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRA 388
Query: 408 DFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPS 467
+F V G P+ D E + YTDW ++P R+ L + DH V P
Sbjct: 389 EFLAGVR------VGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPV 442
Query: 468 VVTADLHARYGSPTYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFS 527
A A G+ Y Y F H +L P W HG E+ ++FG+P+ P+ N++
Sbjct: 443 AQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPL-DPSR----NYT 497
Query: 528 KNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIG 587
+ + + +M YW NFA+TGDPN+ P+D K W Y Q Y+ +
Sbjct: 498 AEEKIFAQRLMRYWANFARTGDPNE--PRDPK----------APQWPPYTAGAQQYVSLD 545
Query: 588 LKP-RVRDHYRATKVAFWKHLVPHLYNLHD 616
L+P VR RA AFW +P L + D
Sbjct: 546 LRPLEVRRGLRAQACAFWNRFLPKLLSATD 575
>gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo
sapiens]
Length = 617
Score = 322 bits (825), Expect = 9e-88
Identities = 215/625 (34%), Positives = 302/625 (48%), Gaps = 77/625 (12%)
Query: 7 PPSLSLSPKPTVGRSLCLTLWFLSLALRASTQAPAPT-VNTHFGKLRGARVPLPSEILGP 65
PP L L L LW L + A + A V G+LRG R+ P GP
Sbjct: 3 PPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPG---GP 59
Query: 66 VDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTA 125
V +LG+P+A PP+G +RFLPPEP WSG+ +AT F VC Q + T P +
Sbjct: 60 VSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNP 119
Query: 126 NLDIVATYIQEPNEDCLYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVY 185
N +E +EDCLYLNV+ P R + PV+V+
Sbjct: 120 N--------RELSEDCLYLNVWTPYP-----------------------RPTSPTPVLVW 148
Query: 186 IHGGSYMEGTGNM--IDGSILASYGNVIVITLNYRVGVLGFLST-GDQAAKGNYGLLDQI 242
I+GG + G ++ DG L +++++NYRVG GFL+ G + A GN GLLDQ
Sbjct: 149 IYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQR 208
Query: 243 QALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWA 302
AL+WV EN+A FGGDP +T+FG GA+ V + LS S GLF RA++QSG+ WA
Sbjct: 209 LALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWA 268
Query: 303 V--NYQPVKYTSLLADKVGCNVLDT----VDMVDCLRQKSAKELVEQD----IQPARYHV 352
+ + + LA VGC T ++V CLR + A+ LV + Q + +
Sbjct: 269 TVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRF 328
Query: 353 AFGPVIDGDVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKF-VEGV----VDPEDGVSGT 407
+F PV+DGD + D PE L+ G+F +++GV + EG F V G D E +S
Sbjct: 329 SFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRA 388
Query: 408 DFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPS 467
+F V G P+ D E + YTDW ++P R+ L + DH V P
Sbjct: 389 EFLAGVR------VGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPV 442
Query: 468 VVTADLHARYGSPTYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFS 527
A A G+ Y Y F H +L P W HG E+ ++FG+P+ P+ N++
Sbjct: 443 AQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPL-DPSR----NYT 497
Query: 528 KNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIG 587
+ + + +M YW NFA+TGDPN+ P+D K W Y Q Y+ +
Sbjct: 498 AEEKIFAQRLMRYWANFARTGDPNE--PRDPK----------APQWPPYTAGAQQYVSLD 545
Query: 588 LKP-RVRDHYRATKVAFWKHLVPHL 611
L+P VR RA AFW +P L
Sbjct: 546 LRPLEVRRGLRAQACAFWNRFLPKL 570
>gi|4557351 butyrylcholinesterase precursor [Homo sapiens]
Length = 602
Score = 306 bits (785), Expect = 4e-83
Identities = 201/606 (33%), Positives = 299/606 (49%), Gaps = 78/606 (12%)
Query: 27 WFLSLAL---RASTQAPAPTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKR 83
WFL L + ++ T+ + T GK+RG + + G V +LG+PYA PP+G R
Sbjct: 15 WFLLLCMLIGKSHTEDDI-IIATKNGKVRGMNLTVFG---GTVTAFLGIPYAQPPLGRLR 70
Query: 84 FLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLY 143
F P+ WS I NAT + C QNI + P + N D+ +EDCLY
Sbjct: 71 FKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDL--------SEDCLY 122
Query: 144 LNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNM--IDG 201
LNV++P A V+++I+GG + GT ++ DG
Sbjct: 123 LNVWIPAPKPKNAT------------------------VLIWIYGGGFQTGTSSLHVYDG 158
Query: 202 SILASYGNVIVITLNYRVGVLGFLST-GDQAAKGNYGLLDQIQALRWVSENIAFFGGDPR 260
LA VIV+++NYRVG LGFL+ G+ A GN GL DQ AL+WV +NIA FGG+P+
Sbjct: 159 KFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPK 218
Query: 261 RITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVN--YQPVKYTSLLADKV 318
+T+FG GA+ VSL LS S LF RAI+QSGS + WAV Y+ T LA
Sbjct: 219 SVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKLT 278
Query: 319 GCNVLDTVDMVDCLRQKSAKELVEQDIQPARY----HVAFGPVIDGDVIPDDPEILMEQG 374
GC+ + +++ CLR K +E++ + Y V FGP +DGD + D P+IL+E G
Sbjct: 279 GCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLELG 338
Query: 375 EFLNYDIMLGVNQGEGLKF-VEGV----VDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDT 429
+F I++GVN+ EG F V G D ++ +F + F +P +
Sbjct: 339 QFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIF------FPGVSEF 392
Query: 430 LRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHH 489
+E+I F YTDW D PE R+ L + D+ ++ P++ + +G+ +FY F H
Sbjct: 393 GKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEHR 452
Query: 490 CQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGD 549
L P W HG E+ +VFG+P+ N++K + +LS ++ W NFAK G+
Sbjct: 453 SSKLPWPEWMGVMHGYEIEFVFGLPLERRD-----NYTKAEEILSRSIVKRWANFAKYGN 507
Query: 550 PNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLK-PRVRDHYRATKVAFWKHLV 608
PN+ T +W + +Q YL + + R+ RA + FW
Sbjct: 508 PNETQNNST-------------SWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSFF 554
Query: 609 PHLYNL 614
P + +
Sbjct: 555 PKVLEM 560
>gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens]
Length = 568
Score = 292 bits (748), Expect = 8e-79
Identities = 204/613 (33%), Positives = 293/613 (47%), Gaps = 90/613 (14%)
Query: 20 RSLCLTLWFLSLALRASTQAPAPTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPI 79
R+ L S A +P P V+T GK+ G V L PV +LG+P+A PP+
Sbjct: 4 RAFILATLSASAAWAGHPSSP-PVVDTVHGKVLGKFVSLEG-FAQPVAIFLGIPFAKPPL 61
Query: 80 GEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNE 139
G RF PP+P WS ++NAT +PP+C Q+ +L FT + + + +E
Sbjct: 62 GPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQ---LLSELFTNRKENIPLKL---SE 115
Query: 140 DCLYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMI 199
DCLYLN+Y P D+ PVMV+IHGG M G +
Sbjct: 116 DCLYLNIYTPA----------------------DLTKKNRLPVMVWIHGGGLMVGAASTY 153
Query: 200 DGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDP 259
DG LA++ NV+V+T+ YR+G+ GF STGD+ ++GN+G LDQ+ ALRWV +NIA FGG+P
Sbjct: 154 DGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNP 213
Query: 260 RRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVK-YTSLLADKV 318
+T+FG G VS+L LS ++ LF RAI +SG AL+S V VK +A
Sbjct: 214 GSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITA 273
Query: 319 GCNVLDTVDMVDCLRQKSAKELVEQDIQ-----------PARYHVAFGPVIDGDVIPDDP 367
GC + MV CLRQK+ +EL+E ++ P G VIDG ++ P
Sbjct: 274 GCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTP 333
Query: 368 EILMEQGEFLNYDIMLGVNQGE----------GLKFVEGVVDPEDGVSGTDFDYSVSNFV 417
E L + F M+G+N+ E EG +D + +S Y +
Sbjct: 334 EELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIA 393
Query: 418 DNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARY 477
L PE T K++ D+ ++ + L D + PSV+ A H
Sbjct: 394 KEL--IPEA------TEKYL----GGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDA 441
Query: 478 GSPTYFYAFYHH--CQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSA 535
G+PTY Y F + S MKP HGDE+ VFG P + S+ ++ LS
Sbjct: 442 GAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKE------GASEEEIRLSK 495
Query: 536 VVMTYWTNFAKTGDPN-KPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRD 594
+VM +W NFA+ G+PN + +P W +YN ++ YL IG +
Sbjct: 496 MVMKFWANFARNGNPNGEGLPH----------------WPEYNQKEG-YLQIGANTQAAQ 538
Query: 595 HYRATKVAFWKHL 607
+ +VAFW +L
Sbjct: 539 KLKDKEVAFWTNL 551
>gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens]
Length = 566
Score = 292 bits (748), Expect = 8e-79
Identities = 199/590 (33%), Positives = 286/590 (48%), Gaps = 88/590 (14%)
Query: 42 PTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATH 101
P V+T GK+ G V L PV +LG+P+A PP+G RF PP+P WS ++NAT
Sbjct: 24 PVVDTVHGKVLGKFVSLEG-FAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATS 82
Query: 102 FPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDGSGAKKQGE 161
+PP+C Q+ +L FT + + + +EDCLYLN+Y P
Sbjct: 83 YPPMCTQDPKAGQ---LLSELFTNRKENIPLKL---SEDCLYLNIYTPA----------- 125
Query: 162 DLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGV 221
D+ PVMV+IHGG M G + DG LA++ NV+V+T+ YR+G+
Sbjct: 126 -----------DLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGI 174
Query: 222 LGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSH 281
GF STGD+ ++GN+G LDQ+ ALRWV +NIA FGG+P +T+FG G VS+L LS
Sbjct: 175 WGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSP 234
Query: 282 HSEGLFQRAIIQSGSALSSWAVNYQPVK-YTSLLADKVGCNVLDTVDMVDCLRQKSAKEL 340
++ LF RAI +SG AL+S V VK +A GC + MV CLRQK+ +EL
Sbjct: 235 LAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEEL 294
Query: 341 VEQDIQ-----------PARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLGVNQGE 389
+E ++ P G VIDG ++ PE L + F M+G+N+ E
Sbjct: 295 LETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQE 354
Query: 390 ---------GLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTD 440
EG +D + +S Y + L PE T K++
Sbjct: 355 FGWLIPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKEL--IPEA------TEKYL--- 403
Query: 441 WADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHH--CQSLMKPAW 498
D+ ++ + L D + PSV+ A H G+PTY Y F + S MKP
Sbjct: 404 -GGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKT 462
Query: 499 SDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN-KPVPQD 557
HGDE+ VFG P + S+ ++ LS +VM +W NFA+ G+PN + +P
Sbjct: 463 VIGDHGDELFSVFGAPFLKE------GASEEEIRLSKMVMKFWANFARNGNPNGEGLPH- 515
Query: 558 TKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHL 607
W +YN ++ YL IG + + +VAFW +L
Sbjct: 516 ---------------WPEYNQKEG-YLQIGANTQAAQKLKDKEVAFWTNL 549
>gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens]
Length = 567
Score = 292 bits (747), Expect = 1e-78
Identities = 199/591 (33%), Positives = 286/591 (48%), Gaps = 89/591 (15%)
Query: 42 PTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATH 101
P V+T GK+ G V L PV +LG+P+A PP+G RF PP+P WS ++NAT
Sbjct: 24 PVVDTVHGKVLGKFVSLEG-FAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATS 82
Query: 102 FPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDGSGAKKQGE 161
+PP+C Q+ +L FT + + + +EDCLYLN+Y P
Sbjct: 83 YPPMCTQDPKAGQ---LLSELFTNRKENIPLKL---SEDCLYLNIYTPA----------- 125
Query: 162 DLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGV 221
D+ PVMV+IHGG M G + DG LA++ NV+V+T+ YR+G+
Sbjct: 126 -----------DLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGI 174
Query: 222 LGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSH 281
GF STGD+ ++GN+G LDQ+ ALRWV +NIA FGG+P +T+FG G VS+L LS
Sbjct: 175 WGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSP 234
Query: 282 HSEGLFQRAIIQSGSALSSWAVNYQPVK-YTSLLADKVGCNVLDTVDMVDCLRQKSAKEL 340
++ LF RAI +SG AL+S V VK +A GC + MV CLRQK+ +EL
Sbjct: 235 LAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEEL 294
Query: 341 VEQDIQ-----------PARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLGVNQGE 389
+E ++ P G VIDG ++ PE L + F M+G+N+ E
Sbjct: 295 LETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQE 354
Query: 390 ----------GLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYT 439
EG +D + +S Y + L PE T K++
Sbjct: 355 FGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKEL--IPEA------TEKYL-- 404
Query: 440 DWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHH--CQSLMKPA 497
D+ ++ + L D + PSV+ A H G+PTY Y F + S MKP
Sbjct: 405 --GGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPK 462
Query: 498 WSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN-KPVPQ 556
HGDE+ VFG P + S+ ++ LS +VM +W NFA+ G+PN + +P
Sbjct: 463 TVIGDHGDELFSVFGAPFLKE------GASEEEIRLSKMVMKFWANFARNGNPNGEGLPH 516
Query: 557 DTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHL 607
W +YN ++ YL IG + + +VAFW +L
Sbjct: 517 ----------------WPEYNQKEG-YLQIGANTQAAQKLKDKEVAFWTNL 550
>gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens]
Length = 623
Score = 288 bits (738), Expect = 1e-77
Identities = 193/588 (32%), Positives = 295/588 (50%), Gaps = 69/588 (11%)
Query: 29 LSLALRASTQAPA-PTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPP 87
L L +R Q A P TH G++ G+ V + G V +LG+P+A PP+G RF PP
Sbjct: 82 LLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAG-VQTFLGIPFAKPPLGPLRFAPP 140
Query: 88 EPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVY 147
EPP SWSG+R+ T P +C Q++ E + T D ++ EDCLYL++Y
Sbjct: 141 EPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMS-------EDCLYLSIY 193
Query: 148 VPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSILASY 207
P G+ PVMV+IHGG+ + G ++ DGS+LA+
Sbjct: 194 TPAHSHEGSNL----------------------PVMVWIHGGALVFGMASLYDGSMLAAL 231
Query: 208 GNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGS 267
NV+V+ + YR+GVLGF STGD+ A GN+G LDQ+ ALRWV +NIA FGG+P R+T+FG
Sbjct: 232 ENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGE 291
Query: 268 GIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVD 327
G + VS L +S S+GLF AI++SG AL + ++++A+ C+ +D+
Sbjct: 292 SAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEA 351
Query: 328 MVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLGVNQ 387
+V CLR KS +E++ + +P + V+DG +P P+ L+ +F ++GVN
Sbjct: 352 LVGCLRGKSKEEILAIN-KPFK---MIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNN 407
Query: 388 GEG---LKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADR 444
E + V + D + + ++ + L P D LRE D
Sbjct: 408 NEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEY------IGDN 461
Query: 445 DNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSL--MKPAWSDAA 502
+P+T + + D +V P++ A +P YFY F H L ++P A
Sbjct: 462 GDPQTLQAQFQEMMADSMFVIPALQVAHFQCS-RAPVYFYEFQHQPSWLKNIRPPHMKAD 520
Query: 503 HGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN-KPVPQDTKFI 561
HGDE+P+VF G F++ + LS +M YW NFA+ G+PN + +P
Sbjct: 521 HGDELPFVFRSFFGGNY----IKFTEEEEQLSRKMMKYWANFARNGNPNGEGLPH----- 571
Query: 562 HTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVP 609
W ++ +Q YL + L+P V +A ++ FWK +P
Sbjct: 572 -----------WPLFDQEEQ-YLQLNLQPAVGRALKAHRLQFWKKALP 607
>gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens]
Length = 575
Score = 287 bits (734), Expect = 3e-77
Identities = 190/607 (31%), Positives = 304/607 (50%), Gaps = 67/607 (11%)
Query: 19 GRSLCLTLWFLSLALRASTQAPAPTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPP 78
G+ L +W L+ + + A P NT G ++G +V + + PV+ +LGVP+AAPP
Sbjct: 9 GQILIWAIWVLAAPTKGPS-AEGPQRNTRLGWIQGKQVTVLGSPV-PVNVFLGVPFAAPP 66
Query: 79 IGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQE-- 136
+G RF P+P W +R AT +P +C QN W + ++ + +
Sbjct: 67 LGSLRFTNPQPASPWDNLREATSYPNLCLQNSE----------WLLLDQHMLKVHYPKFG 116
Query: 137 PNEDCLYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTG 196
+EDCLYLN+Y P +G+K PV+V+ GG++ G+
Sbjct: 117 VSEDCLYLNIYAPAHADTGSKL----------------------PVLVWFPGGAFKTGSA 154
Query: 197 NMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFG 256
++ DGS LA+Y +V+V+ + YR+G+ GF +T DQ A GN+ DQ+ AL WV +NI FFG
Sbjct: 155 SIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFG 214
Query: 257 GDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSW--AVNYQPVKYTSLL 314
GDP +T+FG GA VS L LS ++GLF +AI++SG A+ + A +Y+ + ++
Sbjct: 215 GDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVV 274
Query: 315 ADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQG 374
A G N D+ ++ CLR K +KEL + ++ +F V+DG P++P L+ Q
Sbjct: 275 AHFCGNNASDSEALLRCLRTKPSKEL----LTLSQKTKSFTRVVDGAFFPNEPLDLLSQK 330
Query: 375 EFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETI 434
F ++GVN E F+ + + + +SG++ ++ + + N+ P L
Sbjct: 331 AFKAIPSIIGVNNHE-CGFLLPMKEAPEILSGSNKSLAL-HLIQNILHIPPQYLHLVANE 388
Query: 435 KFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYH--HCQS 492
F D+ + R +L+ L D +V P+++TA H G+P YFY F H C
Sbjct: 389 YF-----HDKHSLTEIRDSLLDLLGDVFFVVPALITARYHRDAGAPVYFYEFRHRPQCFE 443
Query: 493 LMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNK 552
KPA+ A H DEV +VFG + + ++ + +LS +M YW FA+TG+PN
Sbjct: 444 DTKPAFVKADHADEVRFVFGGAFLKGDIVMFEGATEEEKLLSRKMMKYWATFARTGNPNG 503
Query: 553 PVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLY 612
+ W YN +Q YL + L + + +V FW +P +
Sbjct: 504 N---------------DLSLWPAYNLTEQ-YLQLDLNMSLGQRLKEPRVDFWTSTIPLIL 547
Query: 613 NLHDMFH 619
+ DM H
Sbjct: 548 SASDMLH 554
>gi|148536848 carboxyl ester lipase precursor [Homo sapiens]
Length = 756
Score = 286 bits (731), Expect = 7e-77
Identities = 222/682 (32%), Positives = 305/682 (44%), Gaps = 110/682 (16%)
Query: 17 TVGRSLCLTLWFLSLALRASTQAPAPTVNTHFGKLRGARVPLPSEILGP-VDQYLGVPYA 75
T+GR L L + L+ ++ A V T G + G L +LG VD + G+P+A
Sbjct: 3 TMGR-LQLVVLGLTCCWAVASAAKLGAVYTEGGFVEGVNKKLG--LLGDSVDIFKGIPFA 59
Query: 76 APPIGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQ 135
AP K P+P P W G A +F C Q A + +TY
Sbjct: 60 APT---KALENPQPHPGWQGTLKAKNFKKRCLQ----------------ATITQDSTY-- 98
Query: 136 EPNEDCLYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGT 195
+EDCLYLN++VP G K+ DL PVM++I+GG+++ G+
Sbjct: 99 -GDEDCLYLNIWVP----QGRKQVSRDL-----------------PVMIWIYGGAFLMGS 136
Query: 196 GN--------MIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRW 247
G+ + DG +A+ GNVIV+T NYRVG LGFLSTGD GNYGL DQ A+ W
Sbjct: 137 GHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAW 196
Query: 248 VSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQP 307
V NIA FGGDP IT+FG G + VSL TLS +++GL +RAI QSG ALS W + P
Sbjct: 197 VKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNP 256
Query: 308 VKYTSLLADKVGCNVLDTVDMVDCLRQKSAKEL-------VEQDIQPARYHVAFGPVIDG 360
+ + +A+KVGC V D M CL+ + L + P ++V F PVIDG
Sbjct: 257 LFWAKKVAEKVGCPVGDAARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDG 316
Query: 361 DVIPDDPEILMEQGEFLNYDIMLGVNQGEGLKF----VEGVVDPEDGVSGTDFDYSVSNF 416
D IP DP L ++Y + G N +G F + + V+ DF VS F
Sbjct: 317 DFIPADPINLYANAADIDY--IAGTNNMDGHIFASIDMPAINKGNKKVTEEDFYKLVSEF 374
Query: 417 VDNLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHA- 475
+G + T WA + E ++KT+V TD ++ P+ + H
Sbjct: 375 T-----ITKGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQHRA 429
Query: 476 -RYGSPTYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLS 534
+ TY Y F H + + P W A H D++ YVFG P PT P D +S
Sbjct: 430 NAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGYRP-----QDRTVS 484
Query: 535 AVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRD 594
++ YWTNFAKTGDPN + W Y + YL I K
Sbjct: 485 KAMIAYWTNFAKTGDPN------------MGDSAVPTHWEPYTTENSGYLEITKKMGSSS 532
Query: 595 HYRATKVAFWKHLVPHLYNLHDMFHYTSTTTKVPPPDTTHSSHITRRPNGKTWSTKRPAI 654
R+ + F ++ T T + P T P G + +T P
Sbjct: 533 MKRSLRTNFLRYW---------------TLTYLALPTVTDQEATPVPPTGDSEATPVP-- 575
Query: 655 SPAYSNENAQGSWNGDQDAGPL 676
P +E A GD A P+
Sbjct: 576 -PTGDSETAPVPPTGDSGAPPV 596
>gi|33563374 carboxylesterase 3 [Homo sapiens]
Length = 571
Score = 285 bits (729), Expect = 1e-76
Identities = 197/594 (33%), Positives = 290/594 (48%), Gaps = 72/594 (12%)
Query: 29 LSLALRASTQAPA---PTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFL 85
L LA A+ P P V+T G++RG +V + V+ +LG+P+A PP+G RF
Sbjct: 18 LLLACPATATGPEVAQPEVDTTLGRVRGRQVGVKGTDR-LVNVFLGIPFAQPPLGPDRFS 76
Query: 86 PPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLN 145
P P W G+R+A+ PP+C Q++ E M F N I +EDCL LN
Sbjct: 77 APHPAQPWEGVRDASTAPPMCLQDV-----ESMNSSRFVLN---GKQQIFSVSEDCLVLN 128
Query: 146 VYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSILA 205
VY P E +G+ +PVMV++HGG+ + G DGS LA
Sbjct: 129 VYSPAEVPAGS----------------------GRPVMVWVHGGALITGAATSYDGSALA 166
Query: 206 SYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVF 265
+YG+V+V+T+ YR+GVLGF STGD+ A GN G LD + ALRWV ENIA FGGD +TVF
Sbjct: 167 AYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVF 226
Query: 266 GSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDT 325
G G S +S L LS + GLF RAI QSG + ++ P +A+ + C+
Sbjct: 227 GGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSP 286
Query: 326 VDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLGV 385
+MV CL+QK +ELV + + + +DG V P P+ L+++ F + ++GV
Sbjct: 287 AEMVQCLQQKEGEELV---LSKKLKNTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLMGV 343
Query: 386 NQGEGLKFVE---GVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWA 442
N E + G++D + +S D + + +L PE T+ + ++
Sbjct: 344 NNHEFSWLIPRGWGLLDTMEQMSREDMLAISTPVLTSLDVPPEMMPTVID-------EYL 396
Query: 443 DRDNPETRRKTLVALFTDHQWVEPSVVTADLHAR-YGSPTYFYAFYHHCQSL--MKPAWS 499
++ + F ++ V+ + R GSP +FY F H S +KPAW
Sbjct: 397 GSNSDAQAKCQAFQEFMGDVFINVPTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWV 456
Query: 500 DAAHGDEVPYVFGVPMVGPTD---LFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN-KPVP 555
A HG E +VFG P + FP ++ + LS +M WT+FA+TGDPN K +P
Sbjct: 457 KADHGAEGAFVFGGPFLMDESSRLAFP-EATEEEKQLSLTMMAQWTHFARTGDPNSKALP 515
Query: 556 QDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVP 609
W ++N +Q YL I PR +R + FW +P
Sbjct: 516 ----------------PWPQFNQAEQ-YLEINPVPRAGQKFREAWMQFWSETLP 552
>gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens]
Length = 607
Score = 271 bits (693), Expect = 2e-72
Identities = 186/588 (31%), Positives = 286/588 (48%), Gaps = 85/588 (14%)
Query: 29 LSLALRASTQAPA-PTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPP 87
L L +R Q A P TH G++ G+ V + G V +LG+P+A PP+G RF PP
Sbjct: 82 LLLLVRGQGQDSASPIRTTHTGQVLGSLVHVKGANAG-VQTFLGIPFAKPPLGPLRFAPP 140
Query: 88 EPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVY 147
EPP SWSG+R+ T P +C Q++ E + T D ++ EDCLYL++Y
Sbjct: 141 EPPESWSGVRDGTTHPAMCLQDLTAVESEFLSQFNMTFPSDSMS-------EDCLYLSIY 193
Query: 148 VPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSILASY 207
P G+ PVMV+IHGG+ + G ++ DGS+LA+
Sbjct: 194 TPAHSHEGSNL----------------------PVMVWIHGGALVFGMASLYDGSMLAAL 231
Query: 208 GNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGS 267
NV+V+ + YR+GVLGF STGD+ A GN+G LDQ+ ALRWV +NIA FGG+P R+T+FG
Sbjct: 232 ENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGE 291
Query: 268 GIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVD 327
G + VS L +S S+GLF AI++SG AL + ++++A+ C+ +D+
Sbjct: 292 SAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASSADVISTVVANLSACDQVDSEA 351
Query: 328 MVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLGVNQ 387
+V CLR KS +E++ + +P + V+DG +P P+ L+ +F ++GVN
Sbjct: 352 LVGCLRGKSKEEILAIN-KPFK---MIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNN 407
Query: 388 GEG---LKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADR 444
E + V + D + + ++ + L P D LRE D
Sbjct: 408 NEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEY------IGDN 461
Query: 445 DNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSL--MKPAWSDAA 502
+P+T + + D +V P++ A +P YFY F H L ++P A
Sbjct: 462 GDPQTLQAQFQEMMADSMFVIPALQVAHFQCS-RAPVYFYEFQHQPSWLKNIRPPHMKAD 520
Query: 503 HGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN-KPVPQDTKFI 561
H F++ + LS +M YW NFA+ G+PN + +P
Sbjct: 521 H--------------------VKFTEEEEQLSRKMMKYWANFARNGNPNGEGLPH----- 555
Query: 562 HTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVP 609
W ++ +Q YL + L+P V +A ++ FWK +P
Sbjct: 556 -----------WPLFDQEEQ-YLQLNLQPAVGRALKAHRLQFWKKALP 591
>gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens]
Length = 525
Score = 239 bits (610), Expect = 8e-63
Identities = 173/605 (28%), Positives = 283/605 (46%), Gaps = 113/605 (18%)
Query: 19 GRSLCLTLWFLSLALRASTQAPAPTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPP 78
G+ L +W L+ + + A P NT G ++G +V + + PV+ +LGVP+AAPP
Sbjct: 9 GQILIWAIWVLAAPTKGPS-AEGPQRNTRLGWIQGKQVTVLGSPV-PVNVFLGVPFAAPP 66
Query: 79 IGEKRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQE-- 136
+G RF P+P W +R AT +P +C QN W + ++ + +
Sbjct: 67 LGSLRFTNPQPASPWDNLREATSYPNLCLQNSE----------WLLLDQHMLKVHYPKFG 116
Query: 137 PNEDCLYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTG 196
+EDCLYLN+Y P +G+K PV+V+ GG++ G+
Sbjct: 117 VSEDCLYLNIYAPAHADTGSKL----------------------PVLVWFPGGAFKTGSA 154
Query: 197 NMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFG 256
++ DGS LA+Y +V+V+ + YR+G+ GF +T DQ A GN+ DQ+ AL WV +NI FFG
Sbjct: 155 SIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFG 214
Query: 257 GDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSW--AVNYQPVKYTSLL 314
GDP +T+FG GA VS L LS ++GLF +AI++SG A+ + A +Y+ + ++
Sbjct: 215 GDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAIIPYLEAHDYEKSEDLQVV 274
Query: 315 ADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQG 374
A G N D+ ++ CLR K +KEL + ++ +F V+DG P++P L+ Q
Sbjct: 275 AHFCGNNASDSEALLRCLRTKPSKEL----LTLSQKTKSFTRVVDGAFFPNEPLDLLSQK 330
Query: 375 EFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETI 434
F ++GVN E F+ + + + +SG++ ++ + + N+ P L
Sbjct: 331 AFKAIPSIIGVNNHE-CGFLLPMKEAPEILSGSNKSLAL-HLIQNILHIPPQYLHLVANE 388
Query: 435 KFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSLM 494
F D+ + R +L+ L D +V P+++TA H R G+
Sbjct: 389 YF-----HDKHSLTEIRDSLLDLLGDVFFVVPALITARYH-REGA--------------- 427
Query: 495 KPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPV 554
++ + +LS +M YW FA+TG+PN
Sbjct: 428 --------------------------------TEEEKLLSRKMMKYWATFARTGNPNGN- 454
Query: 555 PQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNL 614
+ W YN +Q YL + L + + +V FW +P + +
Sbjct: 455 --------------DLSLWPAYNLTEQ-YLQLDLNMSLGQRLKEPRVDFWTSTIPLILSA 499
Query: 615 HDMFH 619
DM H
Sbjct: 500 SDMLH 504
>gi|115529439 carboxylesterase 8 (putative) [Homo sapiens]
Length = 491
Score = 234 bits (598), Expect = 2e-61
Identities = 145/384 (37%), Positives = 200/384 (52%), Gaps = 58/384 (15%)
Query: 27 WFLSLALRASTQAPA-----PTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGE 81
W L+L L A T A P V T +G L+G ++ + P+ +LGVP++ PP+G
Sbjct: 7 WSLTLCLMAQTALGALHTKRPQVVTKYGTLQGKQMHVGKT---PIQVFLGVPFSRPPLGI 63
Query: 82 KRFLPPEPPPSWSGIRNATHFPPVCPQNIHTAVPEVMLPV-----WFTANLDIVATYIQE 136
RF PPEPP W GIR+AT +PP C Q + + + W +
Sbjct: 64 LRFAPPEPPEPWKGIRDATTYPPGCLQESWGQLASMYVSTRERYKWLRFS---------- 113
Query: 137 PNEDCLYLNVYVPTEDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTG 196
EDCLYLNVY P A GD PVMV+ GG+++ G
Sbjct: 114 --EDCLYLNVYAP--------------ARAPGDPQ--------LPVMVWFPGGAFIVGAA 149
Query: 197 NMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFG 256
+ +GS LA+ V+++ L +R+G+ GFLST D A+GN+GLLDQ+ ALRWV ENIA FG
Sbjct: 150 SSYEGSDLAAREKVVLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFG 209
Query: 257 GDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLAD 316
GDP +T+FG GA +S L +S + GLF RAI QSG+AL + P+K +A
Sbjct: 210 GDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRLFITSNPLKVAKKVAH 269
Query: 317 KVGCNVLDTVDMVDCLRQKSAKELVEQDIQ-----------PARYHVAFGPVIDGDVIPD 365
GCN T +V+CLR S +++ + P + PV+DG VIPD
Sbjct: 270 LAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPD 329
Query: 366 DPEILMEQGEFLNYDIMLGVNQGE 389
DP +L+ QG+ + +LGVN E
Sbjct: 330 DPLVLLTQGKVSSVPYLLGVNNLE 353
Score = 42.7 bits (99), Expect = 0.001
Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 16/75 (21%)
Query: 533 LSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRV 592
LS +M YW NFA+TG+PN W +YN +D+ YL + RV
Sbjct: 421 LSLQMMKYWANFARTGNPNDG---------------NLPCWPRYN-KDEKYLQLDFTTRV 464
Query: 593 RDHYRATKVAFWKHL 607
+ K+AFW L
Sbjct: 465 GMKLKEKKMAFWMSL 479
>gi|55770862 thyroglobulin [Homo sapiens]
Length = 2768
Score = 193 bits (491), Expect = 5e-49
Identities = 160/541 (29%), Positives = 248/541 (45%), Gaps = 81/541 (14%)
Query: 33 LRASTQAPAPTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPS 92
L P+ ++TH L ++ VDQ+LGVPYAAPP+ E+RF PEP +
Sbjct: 2192 LSYEASVPSVPISTHGRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPL-N 2250
Query: 93 WSGIRNATHFPPVC--PQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPT 150
W+G +A+ C P + P V +EDCLYLNV++P
Sbjct: 2251 WTGSWDASKPRASCWQPGTRTSTSPGV--------------------SEDCLYLNVFIP- 2289
Query: 151 EDGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNM--IDGSILASYG 208
+++A N V+V+ H E + IDGS LA+ G
Sbjct: 2290 ----------QNVAPNAS-------------VLVFFHNTMDREESEGWPAIDGSFLAAVG 2326
Query: 209 NVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSG 268
N+IV+T +YRVGV GFLS+G GN+GLLDQ+ AL WV +I FGGDPRR+++
Sbjct: 2327 NLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADR 2386
Query: 269 IGASCVS--LLTLSHHSEGLFQRAIIQSGSALSSWAV--NYQPVKYTSLLADKVGCNVLD 324
GA S LLT + LF+RA++ GSALS AV + + + LA +V C +
Sbjct: 2387 GGADVASIHLLTARATNSQLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSS 2446
Query: 325 TVDMVDCLRQKSAKELVEQDIQ------PARYHVAFGPVIDGDVIPDDPEILMEQGEFLN 378
+ ++V CLRQK A L + + P Y +GPVIDG + + P +++ ++
Sbjct: 2447 SQEVVSCLRQKPANVLNDAQTKLLAVSGPFHY---WGPVIDGHFLREPPARALKRSLWVE 2503
Query: 379 YDIMLGVNQGEGL-KFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFM 437
D+++G +Q +GL + V E+ T + + N G + + +
Sbjct: 2504 VDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKTAFYQALQNSLGGEDSDARVEAAATWY 2563
Query: 438 YTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSLMKPA 497
Y+ D+ + + L D+ + P + A A+ F YH A
Sbjct: 2564 YSLEHSTDDYASFSRALENATRDYFIICPIIDMASAWAKRARGNVF--MYH--------A 2613
Query: 498 WSDAAHGD-----EVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNK 552
+ HG +V + G+P + FS + LS +M Y+++F ++G+PN
Sbjct: 2614 PENYGHGSLELLADVQFALGLPFY---PAYEGQFSLEEKSLSLKIMQYFSHFIRSGNPNY 2670
Query: 553 P 553
P
Sbjct: 2671 P 2671
>gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 327
Score = 150 bits (379), Expect = 5e-36
Identities = 81/204 (39%), Positives = 125/204 (61%), Gaps = 6/204 (2%)
Query: 188 GGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRW 247
GG++ G+ ++ DGS LA+Y +++V+ + YR+G+ GF +T DQ A GN+ DQ+ AL W
Sbjct: 20 GGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW 79
Query: 248 VSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSW--AVNY 305
V +NI FFGGDP +T+FG +GA VS L LS +EGLF +A+++SG A+ + A +Y
Sbjct: 80 VQKNIEFFGGDPSSVTIFGESVGAISVSSLMLSPMAEGLFHKAVMESGVAIILYLKAHDY 139
Query: 306 QPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPD 365
+ + ++A G N D+ + CLR KS+KEL + ++ AF V+DG P+
Sbjct: 140 EKSEDLQVVAQFCGYNASDSEAPLRCLRTKSSKEL----LTLSQKTKAFTQVVDGAFFPN 195
Query: 366 DPEILMEQGEFLNYDIMLGVNQGE 389
+P L+ Q F ++GVN E
Sbjct: 196 EPLDLLSQKAFKAIPSIIGVNNPE 219
>gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 327
Score = 150 bits (379), Expect = 5e-36
Identities = 81/204 (39%), Positives = 125/204 (61%), Gaps = 6/204 (2%)
Query: 188 GGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRW 247
GG++ G+ ++ DGS LA+Y +++V+ + YR+G+ GF +T DQ A GN+ DQ+ AL W
Sbjct: 20 GGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW 79
Query: 248 VSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSW--AVNY 305
V +NI FFGGDP +T+FG +GA VS L LS +EGLF +A+++SG A+ + A +Y
Sbjct: 80 VQKNIEFFGGDPSSVTIFGESVGAISVSSLILSPMAEGLFHKAVMESGVAIILYLKAHDY 139
Query: 306 QPVKYTSLLADKVGCNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPD 365
+ + ++A G N D+ + CLR KS+KEL + ++ AF V+DG P+
Sbjct: 140 EKSEDLQVVAQFCGYNASDSEAPLRCLRTKSSKEL----LTLSQKTKAFTQVVDGAFFPN 195
Query: 366 DPEILMEQGEFLNYDIMLGVNQGE 389
+P L+ Q F ++GVN E
Sbjct: 196 EPLDLLSQKAFKAIPSIIGVNNPE 219
>gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 131
Score = 92.0 bits (227), Expect = 2e-18
Identities = 38/84 (45%), Positives = 60/84 (71%)
Query: 182 VMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQ 241
V+++ GG++ G+ ++ DGS LA+Y +++V+ + YR+G+ GF +T DQ A GN+ DQ
Sbjct: 20 VLLWFPGGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQ 79
Query: 242 IQALRWVSENIAFFGGDPRRITVF 265
+ AL WV +NI FFGGDP +T+F
Sbjct: 80 VAALSWVQKNIEFFGGDPSSVTIF 103
>gi|18079216 CASK interacting protein 1 [Homo sapiens]
Length = 1431
Score = 33.5 bits (75), Expect = 0.83
Identities = 27/78 (34%), Positives = 33/78 (42%), Gaps = 3/78 (3%)
Query: 35 ASTQAPAPTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWS 94
A + P P H G R P SE GP + P A PP + LPP PPP
Sbjct: 1159 AGPEPPPPLSVYHNGTGTVRRRPA-SEQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGE 1217
Query: 95 GIRNATHFPPVCPQNIHT 112
+ A PPV P+ + T
Sbjct: 1218 ARKPAK--PPVSPKPVLT 1233
>gi|115430245 arylhydrocarbon receptor repressor [Homo sapiens]
Length = 719
Score = 33.5 bits (75), Expect = 0.83
Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 16/114 (14%)
Query: 625 TKVPPPDTTHSSHITRRPNGKTWSTKRPAISPAYSNENAQ--GSWNGDQDAGPLLVENPR 682
T +PP + T++ RRP K +RPA+ SN + + N + D L+ P
Sbjct: 4 TMIPPGECTYAGRKRRRPLQK----QRPAVGAEKSNPSKRHRDRLNAELDHLASLLPFPP 59
Query: 683 DYSTELSVTIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGAGAPELG 736
D ++L L+VL + Y R Q Q S Q AGAP G
Sbjct: 60 DIISKLDK----------LSVLRLSVSYLRVKSFFQVVQEQSSRQPAAGAPSPG 103
>gi|5729962 submaxillary gland androgen regulated protein 3 homolog
B [Homo sapiens]
Length = 79
Score = 33.1 bits (74), Expect = 1.1
Identities = 28/85 (32%), Positives = 31/85 (36%), Gaps = 15/85 (17%)
Query: 27 WFLSLALRASTQAPAPTVNTHFGKLRGARVPLPSEILGPVDQY---LGVPYAAPPIGEKR 83
W L L A+ P + RG R P P L P + P PP G R
Sbjct: 6 WILGLWALAACFTPGESQ-------RGPRGPYPPGPLAPPQPFGPGFVPPPPPPPYGPGR 58
Query: 84 FLPPEPPPSWSGIRNATHFPPVCPQ 108
PP P P GI FPP PQ
Sbjct: 59 IPPPPPAPYGPGI-----FPPPPPQ 78
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 31.6 bits (70), Expect = 3.2
Identities = 17/37 (45%), Positives = 21/37 (56%), Gaps = 2/37 (5%)
Query: 623 TTTKVPPPDTTHSSHITRRPN--GKTWSTKRPAISPA 657
TTT PPP TT SS IT P+ T +T P +P+
Sbjct: 1670 TTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPS 1706
>gi|88758613 CD93 antigen precursor [Homo sapiens]
Length = 652
Score = 31.6 bits (70), Expect = 3.2
Identities = 21/89 (23%), Positives = 34/89 (38%)
Query: 642 PNGKTWSTKRPAISPAYSNENAQGSWNGDQDAGPLLVENPRDYSTELSVTIAVGASLLFL 701
P+G + P+I A + Q GD + L + ++L L
Sbjct: 537 PSGSPGVWREPSIHHATAASGPQEPAGGDSSVATQNNDGTDGQKLLLFYILGTVVAILLL 596
Query: 702 NVLAFAALYYRKDKRRQEPLRQPSPQRGA 730
LA L YRK + ++E ++ PQ A
Sbjct: 597 LALALGLLVYRKRRAKREEKKEKKPQNAA 625
>gi|73695473 roquin [Homo sapiens]
Length = 1133
Score = 31.6 bits (70), Expect = 3.2
Identities = 21/82 (25%), Positives = 30/82 (36%), Gaps = 5/82 (6%)
Query: 29 LSLALRASTQAPAPTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPE 88
L + R S PA + ++ RGA P P G+ Y PP RF+ P
Sbjct: 574 LQMVPRGSQLYPAQQTDVYYQDPRGAAPPFE-----PAPYQQGMYYTPPPQCVSRFVRPP 628
Query: 89 PPPSWSGIRNATHFPPVCPQNI 110
P H+PP + +
Sbjct: 629 PSAPEPAPPYLDHYPPYLQERV 650
>gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo
sapiens]
Length = 5033
Score = 31.2 bits (69), Expect = 4.1
Identities = 18/53 (33%), Positives = 27/53 (50%), Gaps = 4/53 (7%)
Query: 152 DGSGAKKQGEDLADNDGDEDEDIRDS---GAKPVMVYIHGGSYM-EGTGNMID 200
DG GA + D A+ GDE+E + ++ GA + GG + EG G + D
Sbjct: 4399 DGEGASEGAGDAAEGAGDEEEAVHEAGPGGADGAVAVTDGGPFRPEGAGGLGD 4451
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.425
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,157,576
Number of Sequences: 37866
Number of extensions: 1956133
Number of successful extensions: 5930
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 5711
Number of HSP's gapped (non-prelim): 115
length of query: 828
length of database: 18,247,518
effective HSP length: 111
effective length of query: 717
effective length of database: 14,044,392
effective search space: 10069829064
effective search space used: 10069829064
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.