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Search of human proteins with 51479173
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]
(4523 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens] 9060 0.0
gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sap... 5373 0.0
gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 5330 0.0
gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 5294 0.0
gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s... 5291 0.0
gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens] 2159 0.0
gi|75677365 dynein heavy chain domain 3 [Homo sapiens] 2130 0.0
gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens] 2000 0.0
gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens] 1993 0.0
gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens] 1909 0.0
gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens] 1869 0.0
gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens] 1831 0.0
gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens] 1825 0.0
gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens] 1365 0.0
gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens] 1186 0.0
gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sap... 1094 0.0
gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens] 965 0.0
gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [H... 743 0.0
gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens] 187 3e-46
gi|153945715 myosin VC [Homo sapiens] 47 3e-04
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens] 45 0.001
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 44 0.005
gi|58530840 desmoplakin isoform I [Homo sapiens] 44 0.005
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 42 0.014
gi|38348356 testis expressed 9 [Homo sapiens] 42 0.014
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 41 0.031
gi|157388975 coiled-coil domain containing 99 [Homo sapiens] 41 0.031
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 40 0.053
gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens] 40 0.069
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 40 0.069
>gi|51479173 dynein, axonemal, heavy chain 11 [Homo sapiens]
Length = 4523
Score = 9060 bits (23510), Expect = 0.0
Identities = 4523/4523 (100%), Positives = 4523/4523 (100%)
Query: 1 MAAQVAAREARDFREAPTLRLTSGAGLEAVGAVELEEEEENEEEAAARRARSFAQDARVR 60
MAAQVAAREARDFREAPTLRLTSGAGLEAVGAVELEEEEENEEEAAARRARSFAQDARVR
Sbjct: 1 MAAQVAAREARDFREAPTLRLTSGAGLEAVGAVELEEEEENEEEAAARRARSFAQDARVR 60
Query: 61 FLGGRLAMMLGFTEEKWSQYLESEDNRQVLGEFLESTSPACLVFSFAASGRLAASQEIPR 120
FLGGRLAMMLGFTEEKWSQYLESEDNRQVLGEFLESTSPACLVFSFAASGRLAASQEIPR
Sbjct: 61 FLGGRLAMMLGFTEEKWSQYLESEDNRQVLGEFLESTSPACLVFSFAASGRLAASQEIPR 120
Query: 121 DANHKLVFISKKITESIGVNDFSQVVLFGELPALSLGHVSAFLDEILVPVLSNKNNHKSW 180
DANHKLVFISKKITESIGVNDFSQVVLFGELPALSLGHVSAFLDEILVPVLSNKNNHKSW
Sbjct: 121 DANHKLVFISKKITESIGVNDFSQVVLFGELPALSLGHVSAFLDEILVPVLSNKNNHKSW 180
Query: 181 SCFTSQDMEYHIEVMKKKMYIFRGKMSRRTLLPIPTVAGKMDLDQNCSENKPPSNERIIL 240
SCFTSQDMEYHIEVMKKKMYIFRGKMSRRTLLPIPTVAGKMDLDQNCSENKPPSNERIIL
Sbjct: 181 SCFTSQDMEYHIEVMKKKMYIFRGKMSRRTLLPIPTVAGKMDLDQNCSENKPPSNERIIL 240
Query: 241 HAIESVVIEWSHQIQEIIERDSVQRLLNGLHLSPQAELDFWMMRRENLSCIYDQLQAPVV 300
HAIESVVIEWSHQIQEIIERDSVQRLLNGLHLSPQAELDFWMMRRENLSCIYDQLQAPVV
Sbjct: 241 HAIESVVIEWSHQIQEIIERDSVQRLLNGLHLSPQAELDFWMMRRENLSCIYDQLQAPVV 300
Query: 301 LKMVKILTTKQSSYFPTLKDIFLAVENALLEAQDVELYLRPLRRHIQCLQETEFPQTRIL 360
LKMVKILTTKQSSYFPTLKDIFLAVENALLEAQDVELYLRPLRRHIQCLQETEFPQTRIL
Sbjct: 301 LKMVKILTTKQSSYFPTLKDIFLAVENALLEAQDVELYLRPLRRHIQCLQETEFPQTRIL 360
Query: 361 IAPLFHTICLIWSHSKFYNTPARVIVLLQEFCNLFINQATAYLSPEDLLRGEIEESLEKV 420
IAPLFHTICLIWSHSKFYNTPARVIVLLQEFCNLFINQATAYLSPEDLLRGEIEESLEKV
Sbjct: 361 IAPLFHTICLIWSHSKFYNTPARVIVLLQEFCNLFINQATAYLSPEDLLRGEIEESLEKV 420
Query: 421 QVAVNILKTFKNSFFNYRKKLASYFMGRKLRPWDFQSHLVFCRFDKFLDRLIKIEDIFAT 480
QVAVNILKTFKNSFFNYRKKLASYFMGRKLRPWDFQSHLVFCRFDKFLDRLIKIEDIFAT
Sbjct: 421 QVAVNILKTFKNSFFNYRKKLASYFMGRKLRPWDFQSHLVFCRFDKFLDRLIKIEDIFAT 480
Query: 481 TLEFEKLERLEFGGTKGAILNGQVHEMSEELMELCKLFKQSTYDPSDCTNMEFESDYVAF 540
TLEFEKLERLEFGGTKGAILNGQVHEMSEELMELCKLFKQSTYDPSDCTNMEFESDYVAF
Sbjct: 481 TLEFEKLERLEFGGTKGAILNGQVHEMSEELMELCKLFKQSTYDPSDCTNMEFESDYVAF 540
Query: 541 KSKTLEFDRRLGTIICEAFFNCNGLEAAFKLLTIFGNFLEKPVVMEIFSLHYSTLVHMFN 600
KSKTLEFDRRLGTIICEAFFNCNGLEAAFKLLTIFGNFLEKPVVMEIFSLHYSTLVHMFN
Sbjct: 541 KSKTLEFDRRLGTIICEAFFNCNGLEAAFKLLTIFGNFLEKPVVMEIFSLHYSTLVHMFN 600
Query: 601 TELDVCKQLYNEHMKQIECGHVVLNKNMPFTSGNMKWAQQVLQRLQMFWSNFASLRYLFL 660
TELDVCKQLYNEHMKQIECGHVVLNKNMPFTSGNMKWAQQVLQRLQMFWSNFASLRYLFL
Sbjct: 601 TELDVCKQLYNEHMKQIECGHVVLNKNMPFTSGNMKWAQQVLQRLQMFWSNFASLRYLFL 660
Query: 661 GNPDHALVYQKYVEMTTLLDQFESRIYNEWKSNVDEICEFNLNQPLVKFSAINGLLCVNF 720
GNPDHALVYQKYVEMTTLLDQFESRIYNEWKSNVDEICEFNLNQPLVKFSAINGLLCVNF
Sbjct: 661 GNPDHALVYQKYVEMTTLLDQFESRIYNEWKSNVDEICEFNLNQPLVKFSAINGLLCVNF 720
Query: 721 DPKLVAVLREVKYLLMLKKQDIPDSALAIFKKRNTILKYIGNLDLLVQGYNKLKQTLLEV 780
DPKLVAVLREVKYLLMLKKQDIPDSALAIFKKRNTILKYIGNLDLLVQGYNKLKQTLLEV
Sbjct: 721 DPKLVAVLREVKYLLMLKKQDIPDSALAIFKKRNTILKYIGNLDLLVQGYNKLKQTLLEV 780
Query: 781 EYPLIEDELRAIDEQLTAATTWLTWQDDCWGYIERVRAATSELEHRVERTQKNVKVIQQT 840
EYPLIEDELRAIDEQLTAATTWLTWQDDCWGYIERVRAATSELEHRVERTQKNVKVIQQT
Sbjct: 781 EYPLIEDELRAIDEQLTAATTWLTWQDDCWGYIERVRAATSELEHRVERTQKNVKVIQQT 840
Query: 841 MRGWARCVLPPRREHRREAAFTLEDKGDLFTKKYKLIQGDGCKIHNLVEENRKLFKANPS 900
MRGWARCVLPPRREHRREAAFTLEDKGDLFTKKYKLIQGDGCKIHNLVEENRKLFKANPS
Sbjct: 841 MRGWARCVLPPRREHRREAAFTLEDKGDLFTKKYKLIQGDGCKIHNLVEENRKLFKANPS 900
Query: 901 LDTWKIYVEFIDDIVVEGFFQAIMHDLDFFLKNTEKQLKPAPFFQAQMILLPPEIVFKPS 960
LDTWKIYVEFIDDIVVEGFFQAIMHDLDFFLKNTEKQLKPAPFFQAQMILLPPEIVFKPS
Sbjct: 901 LDTWKIYVEFIDDIVVEGFFQAIMHDLDFFLKNTEKQLKPAPFFQAQMILLPPEIVFKPS 960
Query: 961 LDREAGDGFYDLVEEMLCNSFRMSAQMNRIATHLEIKNYQNDMDNMLGLAEVRQEIMNRV 1020
LDREAGDGFYDLVEEMLCNSFRMSAQMNRIATHLEIKNYQNDMDNMLGLAEVRQEIMNRV
Sbjct: 961 LDREAGDGFYDLVEEMLCNSFRMSAQMNRIATHLEIKNYQNDMDNMLGLAEVRQEIMNRV 1020
Query: 1021 VNVINKVLDFRNTLETHTYLWVDDRAEFMKHFLLYGHAVSSDEMDAHANEEIPEQPPTLE 1080
VNVINKVLDFRNTLETHTYLWVDDRAEFMKHFLLYGHAVSSDEMDAHANEEIPEQPPTLE
Sbjct: 1021 VNVINKVLDFRNTLETHTYLWVDDRAEFMKHFLLYGHAVSSDEMDAHANEEIPEQPPTLE 1080
Query: 1081 QFKEQIDIYEALYVQMSKFEDFRVFDSWFKVDMKPFKVSLLTIIKKWSWMFQEHLLRFVI 1140
QFKEQIDIYEALYVQMSKFEDFRVFDSWFKVDMKPFKVSLLTIIKKWSWMFQEHLLRFVI
Sbjct: 1081 QFKEQIDIYEALYVQMSKFEDFRVFDSWFKVDMKPFKVSLLTIIKKWSWMFQEHLLRFVI 1140
Query: 1141 DSLNELQEFIKETDSGLQRELNEGDHDGLVDIMVHLLAVRSRQRATDELFEPLKETITLL 1200
DSLNELQEFIKETDSGLQRELNEGDHDGLVDIMVHLLAVRSRQRATDELFEPLKETITLL
Sbjct: 1141 DSLNELQEFIKETDSGLQRELNEGDHDGLVDIMVHLLAVRSRQRATDELFEPLKETITLL 1200
Query: 1201 ESYGQKMPEQVYIQLEELPERWETTKKIAATVRHEVSPLHNAEVTLIRKKCILFDAKQAE 1260
ESYGQKMPEQVYIQLEELPERWETTKKIAATVRHEVSPLHNAEVTLIRKKCILFDAKQAE
Sbjct: 1201 ESYGQKMPEQVYIQLEELPERWETTKKIAATVRHEVSPLHNAEVTLIRKKCILFDAKQAE 1260
Query: 1261 FRERFRHYAPLGFNAENPYTALDKANEELEALEEEMLQMQESTRLFEVALPEYKQMKQCR 1320
FRERFRHYAPLGFNAENPYTALDKANEELEALEEEMLQMQESTRLFEVALPEYKQMKQCR
Sbjct: 1261 FRERFRHYAPLGFNAENPYTALDKANEELEALEEEMLQMQESTRLFEVALPEYKQMKQCR 1320
Query: 1321 KEIKLLKGLWDVIIYVRRSIDNWTKTQWRQIHVEQMDVELRRFAKASSITEIWSLNKEVR 1380
KEIKLLKGLWDVIIYVRRSIDNWTKTQWRQIHVEQMDVELRRFAKASSITEIWSLNKEVR
Sbjct: 1321 KEIKLLKGLWDVIIYVRRSIDNWTKTQWRQIHVEQMDVELRRFAKASSITEIWSLNKEVR 1380
Query: 1381 VWDAYTGLEGTVKDMTASLRAITELQSPALRDRHWHQLMKAIGVKFLINEATTLADLLAL 1440
VWDAYTGLEGTVKDMTASLRAITELQSPALRDRHWHQLMKAIGVKFLINEATTLADLLAL
Sbjct: 1381 VWDAYTGLEGTVKDMTASLRAITELQSPALRDRHWHQLMKAIGVKFLINEATTLADLLAL 1440
Query: 1441 RLHRVEDDVRRIVDKAVKELGTEKVITEISQTWATMKFSYEVHYRTGIPLLKSDEQLFET 1500
RLHRVEDDVRRIVDKAVKELGTEKVITEISQTWATMKFSYEVHYRTGIPLLKSDEQLFET
Sbjct: 1441 RLHRVEDDVRRIVDKAVKELGTEKVITEISQTWATMKFSYEVHYRTGIPLLKSDEQLFET 1500
Query: 1501 LEHNQVQLQTLLQSKYVEYFIEQVLSWQNKLNIADLVIFTWMEVQRTWSHLESIFVCSED 1560
LEHNQVQLQTLLQSKYVEYFIEQVLSWQNKLNIADLVIFTWMEVQRTWSHLESIFVCSED
Sbjct: 1501 LEHNQVQLQTLLQSKYVEYFIEQVLSWQNKLNIADLVIFTWMEVQRTWSHLESIFVCSED 1560
Query: 1561 IRIQLVKDARRFDGVDAEFKELMFKTAKVENVLEATCRPNLYEKLKDLQSRLSLCEKALA 1620
IRIQLVKDARRFDGVDAEFKELMFKTAKVENVLEATCRPNLYEKLKDLQSRLSLCEKALA
Sbjct: 1561 IRIQLVKDARRFDGVDAEFKELMFKTAKVENVLEATCRPNLYEKLKDLQSRLSLCEKALA 1620
Query: 1621 EYLETKRIAFPRFYFVSSADLLDILSKGAQPKQVTCHLAKLFDSIADLQFEDNQDVSAHR 1680
EYLETKRIAFPRFYFVSSADLLDILSKGAQPKQVTCHLAKLFDSIADLQFEDNQDVSAHR
Sbjct: 1621 EYLETKRIAFPRFYFVSSADLLDILSKGAQPKQVTCHLAKLFDSIADLQFEDNQDVSAHR 1680
Query: 1681 AVGMYSKEKEYVPFQAECECVGHVETWLLQLEQTMQETVRHSITEAIVAYEEKPRELWIF 1740
AVGMYSKEKEYVPFQAECECVGHVETWLLQLEQTMQETVRHSITEAIVAYEEKPRELWIF
Sbjct: 1681 AVGMYSKEKEYVPFQAECECVGHVETWLLQLEQTMQETVRHSITEAIVAYEEKPRELWIF 1740
Query: 1741 DFPAQVALTSSQIWWTTDVGIAFSRLEEGYETALKDFHKKQISQLNTLITLLLGELPPGD 1800
DFPAQVALTSSQIWWTTDVGIAFSRLEEGYETALKDFHKKQISQLNTLITLLLGELPPGD
Sbjct: 1741 DFPAQVALTSSQIWWTTDVGIAFSRLEEGYETALKDFHKKQISQLNTLITLLLGELPPGD 1800
Query: 1801 RQKIMTICTIDVHARDVVAKLISQKQVVVSPQAFTWLSQLRHRWEDTQKHCFVNICDAQF 1860
RQKIMTICTIDVHARDVVAKLISQKQVVVSPQAFTWLSQLRHRWEDTQKHCFVNICDAQF
Sbjct: 1801 RQKIMTICTIDVHARDVVAKLISQKQVVVSPQAFTWLSQLRHRWEDTQKHCFVNICDAQF 1860
Query: 1861 QYFYEYLGNSPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGMM 1920
QYFYEYLGNSPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGMM
Sbjct: 1861 QYFYEYLGNSPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGMM 1920
Query: 1921 VYVFNCSEQMDYKSIGNIYKGLVQTGAWGCFDEFNRISVEVLSVVAVQVKMIHDAIRNRK 1980
VYVFNCSEQMDYKSIGNIYKGLVQTGAWGCFDEFNRISVEVLSVVAVQVKMIHDAIRNRK
Sbjct: 1921 VYVFNCSEQMDYKSIGNIYKGLVQTGAWGCFDEFNRISVEVLSVVAVQVKMIHDAIRNRK 1980
Query: 1981 KRFVFLGEAITLKPSVGIFITMNPGYAGRTELPENLKALFRPCAMVAPDIELICEILLVA 2040
KRFVFLGEAITLKPSVGIFITMNPGYAGRTELPENLKALFRPCAMVAPDIELICEILLVA
Sbjct: 1981 KRFVFLGEAITLKPSVGIFITMNPGYAGRTELPENLKALFRPCAMVAPDIELICEILLVA 2040
Query: 2041 EGFVDARALARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDKNRPEDQVL 2100
EGFVDARALARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDKNRPEDQVL
Sbjct: 2041 EGFVDARALARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDKNRPEDQVL 2100
Query: 2101 MRALRDFNMPKIVTDDIPVFLGLVGDLFPALDVPRRRKLHFEQMVRQSTLELRLQPEESF 2160
MRALRDFNMPKIVTDDIPVFLGLVGDLFPALDVPRRRKLHFEQMVRQSTLELRLQPEESF
Sbjct: 2101 MRALRDFNMPKIVTDDIPVFLGLVGDLFPALDVPRRRKLHFEQMVRQSTLELRLQPEESF 2160
Query: 2161 ILKVVQLEELLAVRHSVFVVGNAGTGKSKILRTLNRTYVNMKQKPVWNDLNPKAVTTDEL 2220
ILKVVQLEELLAVRHSVFVVGNAGTGKSKILRTLNRTYVNMKQKPVWNDLNPKAVTTDEL
Sbjct: 2161 ILKVVQLEELLAVRHSVFVVGNAGTGKSKILRTLNRTYVNMKQKPVWNDLNPKAVTTDEL 2220
Query: 2221 FGFIHHATREWKDGKIVYSYFIGLFSSILREQANLKHDGPKWIVLDGDIDPMWIESLNTV 2280
FGFIHHATREWKDGKIVYSYFIGLFSSILREQANLKHDGPKWIVLDGDIDPMWIESLNTV
Sbjct: 2221 FGFIHHATREWKDGKIVYSYFIGLFSSILREQANLKHDGPKWIVLDGDIDPMWIESLNTV 2280
Query: 2281 MDDNKVLTLASNERIALTPFMRLLFEIHHLRSATPATVSRAGILYVNPQDLGWNPYVASW 2340
MDDNKVLTLASNERIALTPFMRLLFEIHHLRSATPATVSRAGILYVNPQDLGWNPYVASW
Sbjct: 2281 MDDNKVLTLASNERIALTPFMRLLFEIHHLRSATPATVSRAGILYVNPQDLGWNPYVASW 2340
Query: 2341 IDRRRHQSEKANLTILFDKYVPACLDKLRTSFKTITSIPESSLVQTLCVLLECLLTPENV 2400
IDRRRHQSEKANLTILFDKYVPACLDKLRTSFKTITSIPESSLVQTLCVLLECLLTPENV
Sbjct: 2341 IDRRRHQSEKANLTILFDKYVPACLDKLRTSFKTITSIPESSLVQTLCVLLECLLTPENV 2400
Query: 2401 PSDSPKEVYEVYFVFACIWAFGGTLLQDQISDYQADFSRWWQKEMKAVKFPSQGTIFDYY 2460
PSDSPKEVYEVYFVFACIWAFGGTLLQDQISDYQADFSRWWQKEMKAVKFPSQGTIFDYY
Sbjct: 2401 PSDSPKEVYEVYFVFACIWAFGGTLLQDQISDYQADFSRWWQKEMKAVKFPSQGTIFDYY 2460
Query: 2461 VDHKTKKLLPWADKIAQFTMDPDVPLQTVLVHTTETARLRYFMELLLEKGKPLMLVGNAG 2520
VDHKTKKLLPWADKIAQFTMDPDVPLQTVLVHTTETARLRYFMELLLEKGKPLMLVGNAG
Sbjct: 2461 VDHKTKKLLPWADKIAQFTMDPDVPLQTVLVHTTETARLRYFMELLLEKGKPLMLVGNAG 2520
Query: 2521 VGKTVFVGDTLASLSEDYIVSRVPFNYYTTSTALQKILEKPLEKKAGHNYGPGGNKKLIY 2580
VGKTVFVGDTLASLSEDYIVSRVPFNYYTTSTALQKILEKPLEKKAGHNYGPGGNKKLIY
Sbjct: 2521 VGKTVFVGDTLASLSEDYIVSRVPFNYYTTSTALQKILEKPLEKKAGHNYGPGGNKKLIY 2580
Query: 2581 FIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYDRQKVMLKEIHNCQYVACMNPMVGSFTI 2640
FIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYDRQKVMLKEIHNCQYVACMNPMVGSFTI
Sbjct: 2581 FIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYDRQKVMLKEIHNCQYVACMNPMVGSFTI 2640
Query: 2641 NPRLQRHFTVFAFNFPSLDALNTIYGQIFSFHFQQQAFAPSILRSGPTLIQATIAFHQTM 2700
NPRLQRHFTVFAFNFPSLDALNTIYGQIFSFHFQQQAFAPSILRSGPTLIQATIAFHQTM
Sbjct: 2641 NPRLQRHFTVFAFNFPSLDALNTIYGQIFSFHFQQQAFAPSILRSGPTLIQATIAFHQTM 2700
Query: 2701 MCNFLPTAIKFHYIFNLRDLSNVFQGILFASPECLKGPLDLIHLWLHESARVYGDKLIDK 2760
MCNFLPTAIKFHYIFNLRDLSNVFQGILFASPECLKGPLDLIHLWLHESARVYGDKLIDK
Sbjct: 2701 MCNFLPTAIKFHYIFNLRDLSNVFQGILFASPECLKGPLDLIHLWLHESARVYGDKLIDK 2760
Query: 2761 KDCDLFQRRMLETAYKYFEGIDSHMLLQQPLIYCHFADRGKDPHYMPVKDWEVLKTILTE 2820
KDCDLFQRRMLETAYKYFEGIDSHMLLQQPLIYCHFADRGKDPHYMPVKDWEVLKTILTE
Sbjct: 2761 KDCDLFQRRMLETAYKYFEGIDSHMLLQQPLIYCHFADRGKDPHYMPVKDWEVLKTILTE 2820
Query: 2821 TLDNYNELNAAMHLVLFEDAMQHVCRISRILRTPQGCALLVGVGGSGKQSLSRLAAYLRG 2880
TLDNYNELNAAMHLVLFEDAMQHVCRISRILRTPQGCALLVGVGGSGKQSLSRLAAYLRG
Sbjct: 2821 TLDNYNELNAAMHLVLFEDAMQHVCRISRILRTPQGCALLVGVGGSGKQSLSRLAAYLRG 2880
Query: 2881 LEVFQITLTEGYGIQELRVDLANLYIRTGAKNMPTVFLLTDAQVLDESFLVLINDLLASG 2940
LEVFQITLTEGYGIQELRVDLANLYIRTGAKNMPTVFLLTDAQVLDESFLVLINDLLASG
Sbjct: 2881 LEVFQITLTEGYGIQELRVDLANLYIRTGAKNMPTVFLLTDAQVLDESFLVLINDLLASG 2940
Query: 2941 EIPDLFSDEDVDKIISGIHNEVHALGMVDSRENCWKFFMARVRLQLKIILCFSPVGRTLR 3000
EIPDLFSDEDVDKIISGIHNEVHALGMVDSRENCWKFFMARVRLQLKIILCFSPVGRTLR
Sbjct: 2941 EIPDLFSDEDVDKIISGIHNEVHALGMVDSRENCWKFFMARVRLQLKIILCFSPVGRTLR 3000
Query: 3001 VRARKFPAIVNCTAIDWFHAWPQEALVSVSRRFIEETKGIEPVHKDSISLFMAHVHTTVN 3060
VRARKFPAIVNCTAIDWFHAWPQEALVSVSRRFIEETKGIEPVHKDSISLFMAHVHTTVN
Sbjct: 3001 VRARKFPAIVNCTAIDWFHAWPQEALVSVSRRFIEETKGIEPVHKDSISLFMAHVHTTVN 3060
Query: 3061 EMSTRYYQNERRHNYTTPKSFLEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQV 3120
EMSTRYYQNERRHNYTTPKSFLEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQV
Sbjct: 3061 EMSTRYYQNERRHNYTTPKSFLEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQV 3120
Query: 3121 GDLKARLASQEAELQLRNHDAEALITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQ 3180
GDLKARLASQEAELQLRNHDAEALITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQ
Sbjct: 3121 GDLKARLASQEAELQLRNHDAEALITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQ 3180
Query: 3181 RECEADLLKAEPALVAATAALNTLNRVNLSELKAFPNPPIAVTNVTAAVMVLLAPRGRVP 3240
RECEADLLKAEPALVAATAALNTLNRVNLSELKAFPNPPIAVTNVTAAVMVLLAPRGRVP
Sbjct: 3181 RECEADLLKAEPALVAATAALNTLNRVNLSELKAFPNPPIAVTNVTAAVMVLLAPRGRVP 3240
Query: 3241 KDRSWKAAKVFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLKDPEFNPNLIRTKSFAA 3300
KDRSWKAAKVFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLKDPEFNPNLIRTKSFAA
Sbjct: 3241 KDRSWKAAKVFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLKDPEFNPNLIRTKSFAA 3300
Query: 3301 AGLCAWVINIIKFYEVYCDVEPKRQALAQANLELAAATEKLEAIRKKLVDLDRNLSRLTA 3360
AGLCAWVINIIKFYEVYCDVEPKRQALAQANLELAAATEKLEAIRKKLVDLDRNLSRLTA
Sbjct: 3301 AGLCAWVINIIKFYEVYCDVEPKRQALAQANLELAAATEKLEAIRKKLVDLDRNLSRLTA 3360
Query: 3361 SFEKATAEKVRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLL 3420
SFEKATAEKVRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLL
Sbjct: 3361 SFEKATAEKVRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLL 3420
Query: 3421 TAAFVSYVGPFTRQYRQELVHCKWVPFLQQKVSIPLTEGLDLISMLTDDATIAAWNNEGL 3480
TAAFVSYVGPFTRQYRQELVHCKWVPFLQQKVSIPLTEGLDLISMLTDDATIAAWNNEGL
Sbjct: 3421 TAAFVSYVGPFTRQYRQELVHCKWVPFLQQKVSIPLTEGLDLISMLTDDATIAAWNNEGL 3480
Query: 3481 PSDRMSTENAAILTHCERWPLVIDPQQQGIKWIKNKYGMDLKVTHLGQKGFLNAIETALA 3540
PSDRMSTENAAILTHCERWPLVIDPQQQGIKWIKNKYGMDLKVTHLGQKGFLNAIETALA
Sbjct: 3481 PSDRMSTENAAILTHCERWPLVIDPQQQGIKWIKNKYGMDLKVTHLGQKGFLNAIETALA 3540
Query: 3541 FGDVILIENLEETIDPVLDPLLGRNTIKKGKYIRIGDKECEFNKNFRLILHTKLANPHYK 3600
FGDVILIENLEETIDPVLDPLLGRNTIKKGKYIRIGDKECEFNKNFRLILHTKLANPHYK
Sbjct: 3541 FGDVILIENLEETIDPVLDPLLGRNTIKKGKYIRIGDKECEFNKNFRLILHTKLANPHYK 3600
Query: 3601 PELQAQTTLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLEDDL 3660
PELQAQTTLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLEDDL
Sbjct: 3601 PELQAQTTLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLEDDL 3660
Query: 3661 LLRLSAAEGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENERKINEARECYRPVAARAS 3720
LLRLSAAEGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENERKINEARECYRPVAARAS
Sbjct: 3661 LLRLSAAEGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENERKINEARECYRPVAARAS 3720
Query: 3721 LLYFVINDLQKINPLYQFSLKAFNVLFHRAIEQADKVEDMQGRISILMESITHAVFLYTS 3780
LLYFVINDLQKINPLYQFSLKAFNVLFHRAIEQADKVEDMQGRISILMESITHAVFLYTS
Sbjct: 3721 LLYFVINDLQKINPLYQFSLKAFNVLFHRAIEQADKVEDMQGRISILMESITHAVFLYTS 3780
Query: 3781 QALFEKDKLTFLSQMAFQILLRKKEIDPLELDFLLRFTVEHTHLSPVDFLTSQSWSAIKA 3840
QALFEKDKLTFLSQMAFQILLRKKEIDPLELDFLLRFTVEHTHLSPVDFLTSQSWSAIKA
Sbjct: 3781 QALFEKDKLTFLSQMAFQILLRKKEIDPLELDFLLRFTVEHTHLSPVDFLTSQSWSAIKA 3840
Query: 3841 IAVMEEFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKKSLIQKLILLRAMRPDRMT 3900
IAVMEEFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKKSLIQKLILLRAMRPDRMT
Sbjct: 3841 IAVMEEFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKKSLIQKLILLRAMRPDRMT 3900
Query: 3901 YALRNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEILGKRLGFT 3960
YALRNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEILGKRLGFT
Sbjct: 3901 YALRNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEILGKRLGFT 3960
Query: 3961 IDSGKFHNVSLGQGQETVAEVALEKASKGGHWVILQNVHLVAKWLGTLEKLLERFSQGSH 4020
IDSGKFHNVSLGQGQETVAEVALEKASKGGHWVILQNVHLVAKWLGTLEKLLERFSQGSH
Sbjct: 3961 IDSGKFHNVSLGQGQETVAEVALEKASKGGHWVILQNVHLVAKWLGTLEKLLERFSQGSH 4020
Query: 4021 RDYRVFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHAALYNFDQDTLEICSK 4080
RDYRVFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHAALYNFDQDTLEICSK
Sbjct: 4021 RDYRVFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHAALYNFDQDTLEICSK 4080
Query: 4081 EQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICASVLYNYLEANSKVPWE 4140
EQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICASVLYNYLEANSKVPWE
Sbjct: 4081 EQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICASVLYNYLEANSKVPWE 4140
Query: 4141 DLRYLFGEIMYGGHITDDWDRKLCRVYLEEFMNPSLTEDELMLAPGFAAPPYLDYAGYHQ 4200
DLRYLFGEIMYGGHITDDWDRKLCRVYLEEFMNPSLTEDELMLAPGFAAPPYLDYAGYHQ
Sbjct: 4141 DLRYLFGEIMYGGHITDDWDRKLCRVYLEEFMNPSLTEDELMLAPGFAAPPYLDYAGYHQ 4200
Query: 4201 YIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALSGDELGQSTEEKVKN 4260
YIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALSGDELGQSTEEKVKN
Sbjct: 4201 YIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALSGDELGQSTEEKVKN 4260
Query: 4261 VLDDILEKLPEEFNMAEIMQKNSNRSPYVLVCFQECERMNILIREIRISLEQLDLSLKGE 4320
VLDDILEKLPEEFNMAEIMQKNSNRSPYVLVCFQECERMNILIREIRISLEQLDLSLKGE
Sbjct: 4261 VLDDILEKLPEEFNMAEIMQKNSNRSPYVLVCFQECERMNILIREIRISLEQLDLSLKGE 4320
Query: 4321 LALSPAVEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRELDTWTQDLTLPAV 4380
LALSPAVEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRELDTWTQDLTLPAV
Sbjct: 4321 LALSPAVEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRELDTWTQDLTLPAV 4380
Query: 4381 VWLSGFFNPQSFLTAIMQTMARKNEWPLDKTRLTADVTKKTKEDYGHPPREGAYLHGLFM 4440
VWLSGFFNPQSFLTAIMQTMARKNEWPLDKTRLTADVTKKTKEDYGHPPREGAYLHGLFM
Sbjct: 4381 VWLSGFFNPQSFLTAIMQTMARKNEWPLDKTRLTADVTKKTKEDYGHPPREGAYLHGLFM 4440
Query: 4441 EGARWDTQAGTIVEARLKELACPMPVIFAKATPVDRQETKQTYECPVYRTKLRGPSYIWT 4500
EGARWDTQAGTIVEARLKELACPMPVIFAKATPVDRQETKQTYECPVYRTKLRGPSYIWT
Sbjct: 4441 EGARWDTQAGTIVEARLKELACPMPVIFAKATPVDRQETKQTYECPVYRTKLRGPSYIWT 4500
Query: 4501 FRLKSEEKTAKWVLAGVALLLEA 4523
FRLKSEEKTAKWVLAGVALLLEA
Sbjct: 4501 FRLKSEEKTAKWVLAGVALLLEA 4523
>gi|114155133 dynein, axonemal, heavy chain 9 isoform 2 [Homo sapiens]
Length = 4486
Score = 5373 bits (13938), Expect = 0.0
Identities = 2661/4499 (59%), Positives = 3401/4499 (75%), Gaps = 33/4499 (0%)
Query: 39 EENEEEAAARRARSFAQDARVRFLGGRLAMMLGFTEEKWSQYLESEDNRQVLGEFL---- 94
EE AA D R+R LG +AM L W + S + Q+L FL
Sbjct: 5 EERAALAAENADGEPGADRRLRLLGTYVAMSLRPAAGAWERCAGSAEAEQLLQAFLGRDA 64
Query: 95 -ESTSPACLVFSFAASGRLAASQEIPRD---ANHKLVFISKKITESIGVNDFSQVVLFGE 150
E P +V + E+ + A K +F + E G + F V+ G+
Sbjct: 65 AEGPRPLLVVRPGPRGLAIRPGLEVGPESGLAGAKALFFLRTGPEPPGPDSFRGAVVCGD 124
Query: 151 LPALSLGHVSAFLDEILVPVLSNKNNHKSWSCFTSQDMEYHIEVMKKKMYIFRGKMSRRT 210
LPA L H++A E+++PVL+N+ N +W +D+ H ++ + + ++ +T
Sbjct: 125 LPAAPLEHLAALFSEVVLPVLANEKNRLNWPHMICEDVRRHAHSLQCDLSVILEQVKGKT 184
Query: 211 LLPIPTVAGKMDLDQNCSENKPPSNERIILHAIESVVIEWSHQIQEIIERDSVQRLLNGL 270
LLP+P + KM+ + SE S ++ +++AIES VI+WS+Q+Q +++R+S Q LL G
Sbjct: 185 LLPLPAGSEKMEFADSKSETVLDSIDKSVIYAIESAVIKWSYQVQVVLKRESSQPLLQGE 244
Query: 271 HLSPQAELDFWMMRRENLSCIYDQLQAPVVLKMVKILTTKQSSYFPTLKDIFLAVENALL 330
+ +P+ EL+FW R E+L IY+QL+ V M K+L QSSYFP K ++ V AL
Sbjct: 245 NPTPKVELEFWKSRYEDLKYIYNQLRTITVRGMAKLLDKLQSSYFPAFKAMYRDVVAALA 304
Query: 331 EAQDVELYLRPLRRHIQCLQETEFPQTRILIAPLFHTICLIWSHSKFYNTPARVIVLLQE 390
EAQD+ ++L PL+RH++ L+ EFP+ + + PL H +CLIW+ K Y +P R+ VLLQE
Sbjct: 305 EAQDIHVHLIPLQRHLEALENAEFPEVKPQLRPLLHVVCLIWATCKSYRSPGRLTVLLQE 364
Query: 391 FCNLFINQATAYLSPEDLLRGEIEESLEKVQVAVNILKTFKNSFFNYRKKLASYFM-GRK 449
CNL I QA+ YLSPEDLLR E+EES K+QV + L FK F + R+ L +YF ++
Sbjct: 365 ICNLLIQQASNYLSPEDLLRSEVEESQRKLQVVSDTLSFFKQEFQDRRENLHTYFKENQE 424
Query: 450 LRPWDFQSHLVFCRFDKFLDRLIKIEDIFATTLEFEKLERLEFGGTKGAILNGQVHEMSE 509
++ WDFQS LVF R D FL +L +E + T L+F KL ++EF G +G L+ QV +M E
Sbjct: 425 VKEWDFQSSLVFVRLDGFLGQLHVVEGLLKTALDFHKLGKVEFSGVRGNALSQQVQQMHE 484
Query: 510 ELMELCKLFKQSTYDPSDCTNMEFESDYVAFKSKTLEFDRRLGTIICEAFFNCNGLEAAF 569
E E+ +L S+ D + +FE+D F K + DRRLGTI +AF + GLE AF
Sbjct: 485 EFQEMYRLLSGSSSDCLYLQSTDFENDVSEFNQKVEDLDRRLGTIFIQAFDDAPGLEHAF 544
Query: 570 KLLTIFGNFLEKPVVMEIFSLHYSTLVHMFNTELDVCKQLYNEHMKQ-IECGHVVLNKNM 628
KLL I GN LE+P+V S Y L+ MFN +LD + +Y++H+++ E G ++KNM
Sbjct: 545 KLLDIAGNLLERPLVARDTSDKYLVLIQMFNKDLDAVRMIYSQHVQEEAELGFSPVHKNM 604
Query: 629 PFTSGNMKWAQQVLQRLQMFWSNFASLRYLFLGNPDHALVYQKYVEMTTLLDQFESRIYN 688
P +G ++WAQ++ QR+Q +SNF + + + + + + QKY +M +LL+++E+R+Y
Sbjct: 605 PTVAGGLRWAQELRQRIQGPFSNFGRITHPCMESAEGKRMQQKYEDMLSLLEKYETRLYE 664
Query: 689 EWKSNVDEICEFNLNQPLVKFSAINGLLCVNFDPKLVAVLREVKYLLMLKKQDIPDSALA 748
+W V E ++NL+QPL+K + +NF+P+L++VL+E+ YL + + +P++A A
Sbjct: 665 DWCRTVSEKSQYNLSQPLLKRDPETKEITINFNPQLISVLKEMSYLEPREMKHMPETAAA 724
Query: 749 IFKKRNTILKYIGNLDLLVQGYNKLKQTLLEVEYPLIEDELRAIDEQLTAATTWLTWQDD 808
+F R+ + + NL+L+ YNK+ +TLLEVE+PL+E+EL+ ID +L AA L W+ +
Sbjct: 725 MFSSRDFYRQLVANLELMANWYNKVMKTLLEVEFPLVEEELQNIDLRLRAAEETLNWKTE 784
Query: 809 -CWGYIERVRAATSELEHRVERTQKNVKVIQQTMRGWARCVLPPRREHRREAAFTLEDKG 867
Y+ + ++ +LE R+++T+ NV+ IQ M+ W + + + +RE+ +L+D+
Sbjct: 785 GICDYVTEITSSIHDLEQRIQKTKDNVEEIQNIMKTWVTPIFKTK-DGKRESLLSLDDRH 843
Query: 868 DLFTKKYKLIQGDGCKIHNLVEENRKLFKANPSLDTWKIYVEFIDDIVVEGFFQAIMHDL 927
D K Y LI+ G KIH LV+EN LF A+P+ + WK YV ID++++ GFF AI L
Sbjct: 844 DRMEKYYNLIKESGLKIHALVQENLGLFSADPTSNIWKTYVNSIDNLLLNGFFLAIECSL 903
Query: 928 DFFLKNTEKQLKPAPFFQAQMILLPPEIVFKPSLDREAGDGFYDLVEEMLCNSFRMSAQM 987
+ L+NTE + P F+AQ+ L PE+VF PSL+ GF D+VE ++ + FR+ + +
Sbjct: 904 KYLLENTECKAGLTPIFEAQLSLAIPELVFYPSLESGVKGGFCDIVEGLITSIFRIPSLV 963
Query: 988 NRIATHLEIKNYQNDMDNMLGLAEVRQEIMNRVVNVINKVLDFRNTLETHTYLWVDDRAE 1047
R++ +YQ D+D + LA +R+ +M RV ++ +++T ++YL+V+DR E
Sbjct: 964 PRLSPQNGSPHYQVDLDGIPDLANMRRTLMERVQRMMGLCCGYQSTFSQYSYLYVEDRKE 1023
Query: 1048 FMKHFLLYGHAVSSDEMDAHANEEIPEQPPTLEQFKEQIDIYEALYVQMSKFEDFRVFDS 1107
+ FLLYGH ++ +E++ H + IPE PP L QFK QID YE LY ++ + E +VFD
Sbjct: 1024 VLGQFLLYGHILTPEEIEDHVEDGIPENPPLLSQFKVQIDSYETLYEEVCRLEPIKVFDG 1083
Query: 1108 WFKVDMKPFKVSLLTIIKKWSWMFQEHLLRFVIDSLNELQEFIKETDSGLQRELNEGDHD 1167
W K+D++PFK SLL IIK+WS +F++HL+ V SL L FIK+++SGL +++ +GD
Sbjct: 1084 WMKIDIRPFKASLLNIIKRWSLLFKQHLVDHVTHSLANLDAFIKKSESGLLKKVEKGDFQ 1143
Query: 1168 GLVDIMVHLLAVRSRQRATDELFEPLKETITLLESYGQKMPEQVYIQLEELPERWETTKK 1227
GLV+IM HL+AV+ RQ TDE+FEPLK+TI LL++Y Q++PE V+ QLEELPE+W KK
Sbjct: 1144 GLVEIMGHLMAVKERQSNTDEMFEPLKQTIELLKTYEQELPETVFKQLEELPEKWNNIKK 1203
Query: 1228 IAATVRHEVSPLHNAEVTLIRKKCILFDAKQAEFRERFRHYAPLGFNAENPYTALDKANE 1287
+A TV+ +V+PL EVTL+R++C FDA+Q +F E+F AP F++ +P+ LD +
Sbjct: 1204 VAITVKQQVAPLQANEVTLLRQRCTAFDAEQQQFWEQFHKEAPFRFDSIHPHQMLDARHI 1263
Query: 1288 ELEALEEEMLQMQESTRLFEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTKTQ 1347
E++ +E M + ES LFEV +P+YKQ++QCRKE+ LK LWD I V SI W T
Sbjct: 1264 EIQQMESTMASISESASLFEVNVPDYKQLRQCRKEVCQLKELWDTIGMVTSSIHAWETTP 1323
Query: 1348 WRQIHVEQMDVELRRFAKASSITEIWSLNKEVRVWDAYTGLEGTVKDMTASLRAITELQS 1407
WR I+VE M++E ++FA+ I +L+KEVR WDA+TGLE TV + +SLRA+ ELQ+
Sbjct: 1324 WRNINVEAMELECKQFAR-----HIRNLDKEVRAWDAFTGLESTVWNTLSSLRAVAELQN 1378
Query: 1408 PALRDRHWHQLMKAIGVKFLINEATTLADLLALRLHRVEDDVRRIVDKAVKELGTEKVIT 1467
PA+R+RHW QLM+A GV F +++ TTLA LL L+LH ED+VR IVDKA KE+G EK +
Sbjct: 1379 PAIRERHWRQLMQATGVSFTMDQDTTLAHLLQLQLHHYEDEVRGIVDKAAKEMGMEKTLK 1438
Query: 1468 EISQTWATMKFSYEVHYRTGIPLLKSDEQLFETLEHNQVQLQTLLQSKYVEYFIEQVLSW 1527
E+ TWA M+F YE H RT +PLL SDE L E LE NQVQLQ L+ SKYV +F+E+V W
Sbjct: 1439 ELQTTWAGMEFQYEPHPRTNVPLLCSDEDLIEVLEDNQVQLQNLVMSKYVAFFLEEVSGW 1498
Query: 1528 QNKLNIADLVIFTWMEVQRTWSHLESIFVCSEDIRIQLVKDARRFDGVDAEFKELMFKTA 1587
Q KL+ D VI W EVQRTW+HLESIF SEDIR QL +D++RF+G+D +FKEL +
Sbjct: 1499 QKKLSTVDAVISIWFEVQRTWTHLESIFTGSEDIRAQLPQDSKRFEGIDIDFKELAYDAQ 1558
Query: 1588 KVENVLEATCRPNLYEKLKDLQSRLSLCEKALAEYLETKRIAFPRFYFVSSADLLDILSK 1647
K+ NV++ T +P LYEKL+D+Q RL LCEKALAEYL+TKR+AFPRFYF+SS+DLLDILS
Sbjct: 1559 KIPNVVQTTNKPGLYEKLEDIQGRLCLCEKALAEYLDTKRLAFPRFYFLSSSDLLDILSN 1618
Query: 1648 GAQPKQVTCHLAKLFDSIADLQFE-DNQDVSAHRAVGMYSKEKEYVPFQAECECVGHVET 1706
G P+QV HL+KLFD++A ++F+ D ++GMYSKE+EYV F C+C G VE
Sbjct: 1619 GTAPQQVQRHLSKLFDNMAKMRFQLDASGEPTKTSLGMYSKEEEYVAFSEPCDCSGQVEI 1678
Query: 1707 WLLQLEQTMQETVRHSITEAIVAYEEKPRELWIFDFPAQVALTSSQIWWTTDVGIAFSRL 1766
WL + M+ TVRH +TE + AYEEKPRE W+FD PAQVALT +QIWWTT+VG+AF+RL
Sbjct: 1679 WLNHVLGHMKATVRHEMTEGVTAYEEKPREQWLFDHPAQVALTCTQIWWTTEVGMAFARL 1738
Query: 1767 EEGYETALKDFHKKQISQLNTLITLLLGELPPGDRQKIMTICTIDVHARDVVAKLISQKQ 1826
EEGYE+A+KD++KKQ++QL TLIT+L+G+L GDRQKIMTICTIDVHARDVVAK+I+QK
Sbjct: 1739 EEGYESAMKDYYKKQVAQLKTLITMLIGQLSKGDRQKIMTICTIDVHARDVVAKMIAQK- 1797
Query: 1827 VVVSPQAFTWLSQLRHRWEDTQKHCFVNICDAQFQYFYEYLGNSPRLVITPLTDRCYITL 1886
V + QAF WLSQLRHRW+D KHCF NICDAQF Y YEYLGN+PRLVITPLTDRCYITL
Sbjct: 1798 -VDNAQAFLWLSQLRHRWDDEVKHCFANICDAQFLYSYEYLGNTPRLVITPLTDRCYITL 1856
Query: 1887 TQSLHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTG 1946
TQSLHLTMSGAPAGPAGTGKTETTKDLGRALG++VYVFNCSEQMDYKS GNIYKGL QTG
Sbjct: 1857 TQSLHLTMSGAPAGPAGTGKTETTKDLGRALGILVYVFNCSEQMDYKSCGNIYKGLAQTG 1916
Query: 1947 AWGCFDEFNRISVEVLSVVAVQVKMIHDAIRNRKKRFVFLGEAITLKPSVGIFITMNPGY 2006
AWGCFDEFNRISVEVLSVVAVQVK I DAIR++K+ F FLGE I+L PSVGIFITMNPGY
Sbjct: 1917 AWGCFDEFNRISVEVLSVVAVQVKSIQDAIRDKKQWFSFLGEEISLNPSVGIFITMNPGY 1976
Query: 2007 AGRTELPENLKALFRPCAMVAPDIELICEILLVAEGFVDARALARKFITLYTLCKELLSK 2066
AGRTELPENLK+LFRPCAMV PD ELICEI+LVAEGF++A++LARKFITLY LCKELLSK
Sbjct: 1977 AGRTELPENLKSLFRPCAMVVPDFELICEIMLVAEGFIEAQSLARKFITLYQLCKELLSK 2036
Query: 2067 QDHYDWGLRAIKSVLVVAGSLKRGDKNRPEDQVLMRALRDFNMPKIVTDDIPVFLGLVGD 2126
QDHYDWGLRAIKSVLVVAGSLKRGD +RPEDQVLMR+LRDFN+PKIVTDD+P+F+GL+GD
Sbjct: 2037 QDHYDWGLRAIKSVLVVAGSLKRGDPDRPEDQVLMRSLRDFNIPKIVTDDMPIFMGLIGD 2096
Query: 2127 LFPALDVPRRRKLHFEQMVRQSTLELRLQPEESFILKVVQLEELLAVRHSVFVVGNAGTG 2186
LFPALDVPRRR +FE +VR++ ++L+LQ E++F+LKVVQLEELLAVRHSVFVVG AGTG
Sbjct: 2097 LFPALDVPRRRDPNFEALVRKAIVDLKLQAEDNFVLKVVQLEELLAVRHSVFVVGGAGTG 2156
Query: 2187 KSKILRTLNRTYVNMKQKPVWNDLNPKAVTTDELFGFIHHATREWKDGKIVYSYFIGLFS 2246
KS++LR+L++TY MK++PVW DLNPKAVT DELFG I+ AT EWKDG LFS
Sbjct: 2157 KSQVLRSLHKTYQIMKRRPVWTDLNPKAVTNDELFGIINPATGEWKDG---------LFS 2207
Query: 2247 SILREQANLKHDGPKWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIALTPFMRLLFE 2306
SI+RE AN+ HDGPKWI+LDGDIDPMWIESLNTVMDDNKVLTLASNERI L P M+LLFE
Sbjct: 2208 SIMRELANITHDGPKWILLDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNPTMKLLFE 2267
Query: 2307 IHHLRSATPATVSRAGILYVNPQDLGWNPYVASWIDRRRHQSEKANLTILFDKYVPACLD 2366
I HLR+ATPATVSRAGILY+NP DLGWNP V+SWI++R Q+E+ANLTILFDKY+P CLD
Sbjct: 2268 ISHLRTATPATVSRAGILYINPADLGWNPPVSSWIEKREIQTERANLTILFDKYLPTCLD 2327
Query: 2367 KLRTSFKTITSIPESSLVQTLCVLLECLLTPENVPSDSPKEVYEVYFVFACIWAFGGTLL 2426
LRT FK I IPE S+VQ +C LLECLLT E++P+D PKE+YE YFVFA IWAFGG ++
Sbjct: 2328 TLRTRFKKIIPIPEQSMVQMVCHLLECLLTTEDIPADCPKEIYEHYFVFAAIWAFGGAMV 2387
Query: 2427 QDQISDYQADFSRWWQKEMKAVKFPSQGTIFDYYVDHKTKKLLPWADKIAQFTMDPDVPL 2486
QDQ+ DY+A+FS+WW E K VKFPSQGTIFDYY+D +TKK PW+ + QF DP++PL
Sbjct: 2388 QDQLVDYRAEFSKWWLTEFKTVKFPSQGTIFDYYIDPETKKFEPWSKLVPQFEFDPEMPL 2447
Query: 2487 QTVLVHTTETARLRYFMELLLEKGKPLMLVGNAGVGKTVFVGDTLASLS-EDYIVSRVPF 2545
Q LVHT+ET R+ YFME L+ + +P+MLVG AG GK+V VG LASL E Y+V VPF
Sbjct: 2448 QACLVHTSETIRVCYFMERLMARQRPVMLVGTAGTGKSVLVGAKLASLDPEAYLVKNVPF 2507
Query: 2546 NYYTTSTALQKILEKPLEKKAGHNYGPGGNKKLIYFIDDMNMPEVDLYGTVQPHTLIRQH 2605
NYYTTS LQ +LEKPLEKKAG NYGP GNKKLIYFIDDMNMPEVD YGTVQPHT+IRQH
Sbjct: 2508 NYYTTSAMLQAVLEKPLEKKAGRNYGPPGNKKLIYFIDDMNMPEVDAYGTVQPHTIIRQH 2567
Query: 2606 IDYGHWYDRQKVMLKEIHNCQYVACMNPMVGSFTINPRLQRHFTVFAFNFPSLDALNTIY 2665
+DYGHWYDR K+ LKEI N QYV+CMNP GSFTINPRLQRHF+VF +FP DAL++IY
Sbjct: 2568 LDYGHWYDRSKLSLKEITNVQYVSCMNPTAGSFTINPRLQRHFSVFVLSFPGADALSSIY 2627
Query: 2666 GQIFSFHFQQQAFAPSILRSGPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQ 2725
I + H + F S+ +S P LI +AFHQ + FLPT IKFHYIFNLRD +N+FQ
Sbjct: 2628 SIILTQHLKLGNFPASLQKSIPPLIDLALAFHQKIATTFLPTGIKFHYIFNLRDFANIFQ 2687
Query: 2726 GILFASPECLKGPLDLIHLWLHESARVYGDKLIDKKDCDLFQRRMLETAYKYFEGIDSHM 2785
GILF+S EC+K DLI L+LHES RVY DK++++KD DLF + E K F+ I+ +
Sbjct: 2688 GILFSSVECVKSTWDLIRLYLHESNRVYRDKMVEEKDFDLFDKIQTEVLKKTFDDIEDPV 2747
Query: 2786 -LLQQPLIYCHFADRGKDPHYMPVKDWEVLKTILTETLDNYNELNAAMHLVLFEDAMQHV 2844
Q P +YCHFA+ +P YMPV+ WE+L L E L+N+NE+N M LVLFEDAM+HV
Sbjct: 2748 EQTQSPNLYCHFANGIGEPKYMPVQSWELLTQTLVEALENHNEVNTVMDLVLFEDAMRHV 2807
Query: 2845 CRISRILRTPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYGIQELRVDLANL 2904
C I+RIL +P+G ALLVGVGGSGKQSL+RLAA++ ++VFQITL +GY IQ+ ++DLA+L
Sbjct: 2808 CHINRILESPRGNALLVGVGGSGKQSLTRLAAFISSMDVFQITLRKGYQIQDFKMDLASL 2867
Query: 2905 YIRTGAKNMPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDKIISGIHNEVHA 2964
++ G KN+ TVFL+TDAQV DE FLVLINDLLASGEIPDL+SD++V+ IIS + NEV +
Sbjct: 2868 CLKAGVKNLNTVFLMTDAQVADERFLVLINDLLASGEIPDLYSDDEVENIISNVRNEVKS 2927
Query: 2965 LGMVDSRENCWKFFMARVRLQLKIILCFSPVGRTLRVRARKFPAIVNCTAIDWFHAWPQE 3024
G+VD+RENCWKFF+ R+R QLK+ LCFSPVG LRVR+RKFPAIVNCTAI WFH WPQ+
Sbjct: 2928 QGLVDNRENCWKFFIDRIRRQLKVTLCFSPVGNKLRVRSRKFPAIVNCTAIHWFHEWPQQ 2987
Query: 3025 ALVSVSRRFIEETKGIEPVHKDSISLFMAHVHTTVNEMSTRYYQNERRHNYTTPKSFLEQ 3084
AL SVS RF++ T+GIEP K SIS FMA VHT+VN+ S Y NE+R+NYTTPKSFLE
Sbjct: 2988 ALESVSLRFLQNTEGIEPTVKQSISKFMAFVHTSVNQTSQSYLSNEQRYNYTTPKSFLEF 3047
Query: 3085 ISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLASQEAELQLRNHDAEAL 3144
I L+++LL + + E+ K ERL NG+ KL +T++QV DLKA+LA+QE EL+ +N DA+ L
Sbjct: 3048 IRLYQSLLHRHRKELKCKTERLENGLLKLHSTSAQVDDLKAKLAAQEVELKQKNEDADKL 3107
Query: 3145 ITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQRECEADLLKAEPALVAATAALNTL 3204
I +G++T+KVSREK +AD EE+KV I EV QKQ++CE DL KAEPAL AA AALNTL
Sbjct: 3108 IQVVGVETDKVSREKAMADEEEQKVAVIMLEVKQKQKDCEEDLAKAEPALTAAQAALNTL 3167
Query: 3205 NRVNLSELKAFPNPPIAVTNVTAAVMVLLAPRGRVPKDRSWKAAKVFMGKVDDFLQALIN 3264
N+ NL+ELK+F +PP+AV+NV+AAVMVL+APRGRVPKDRSWKAAKV M KVD FL +LIN
Sbjct: 3168 NKTNLTELKSFGSPPLAVSNVSAAVMVLMAPRGRVPKDRSWKAAKVTMAKVDGFLDSLIN 3227
Query: 3265 YDKEHIPENCLKVVNEHYLKDPEFNPNLIRTKSFAAAGLCAWVINIIKFYEVYCDVEPKR 3324
++KE+I ENCLK + YL+DPEFNP + TKS+AAAGLC+WVINI++FYEV+CDVEPKR
Sbjct: 3228 FNKENIHENCLKAIRP-YLQDPEFNPEFVATKSYAAAGLCSWVINIVRFYEVFCDVEPKR 3286
Query: 3325 QALAQANLELAAATEKLEAIRKKLVDLDRNLSRLTASFEKATAEKVRCQEEVNQTNKTIK 3384
QAL +A +L AA EKL AI+ K+ L+ NL++LTA FEKATA+K++CQ+E T TI
Sbjct: 3287 QALNKATADLTAAQEKLAAIKAKIAHLNENLAKLTARFEKATADKLKCQQEAEVTAVTIS 3346
Query: 3385 LANRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLLTAAFVSYVGPFTRQYRQELVHCKW 3444
LANRLV L ++ +RW ++++F+ QE+TLCGD+LL AF+SY+G FT++YRQ L+ W
Sbjct: 3347 LANRLVGGLASENVRWADAVQNFKQQERTLCGDILLITAFISYLGFFTKKYRQSLLDRTW 3406
Query: 3445 VPFLQQ-KVSIPLTEGLDLISMLTDDATIAAWNNEGLPSDRMSTENAAILTHCERWPLVI 3503
P+L Q K IP+T LD + ML DDA +AAW NEGLP+DRMS ENA IL +CERWPL++
Sbjct: 3407 RPYLSQLKTPIPVTPALDPLRMLMDDADVAAWQNEGLPADRMSVENATILINCERWPLMV 3466
Query: 3504 DPQQQGIKWIKNKYGMDLKVTHLGQKGFLNAIETALAFGDVILIENLEETIDPVLDPLLG 3563
DPQ QGIKWIKNKYG DL+VT +GQKG+L IE AL G V+LIENLEE+IDPVL PLLG
Sbjct: 3467 DPQLQGIKWIKNKYGEDLRVTQIGQKGYLQIIEQALEAGAVVLIENLEESIDPVLGPLLG 3526
Query: 3564 RNTIKKGKYIRIGDKECEFNKNFRLILHTKLANPHYKPELQAQTTLLNFTVTEDGLEAQL 3623
R IKKG++I+IGDKECE+N FRLILHTKLANPHY+PELQAQ TL+NFTVT DGLE QL
Sbjct: 3527 REVIKKGRFIKIGDKECEYNPKFRLILHTKLANPHYQPELQAQATLINFTVTRDGLEDQL 3586
Query: 3624 LAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLEDDLLLRLSAAEGSFLDDTKLVERLEA 3683
LA VVS+ERPDLE+LK LTK QN FKI LK LED LL RLS+A G+FL +T LVE LE
Sbjct: 3587 LAAVVSMERPDLEQLKSDLTKQQNGFKITLKTLEDSLLSRLSSASGNFLGETVLVENLEI 3646
Query: 3684 TKTTVAEIEHKVIEAKENERKINEARECYRPVAARASLLYFVINDLQKINPLYQFSLKAF 3743
TK T AE+E KV EAK E KINEARE YRP AARASLLYF++NDL KI+P+YQFSLKAF
Sbjct: 3647 TKQTAAEVEKKVQEAKVTEVKINEAREHYRPAAARASLLYFIMNDLSKIHPMYQFSLKAF 3706
Query: 3744 NVLFHRAIEQADKVEDMQGRISILMESITHAVFLYTSQALFEKDKLTFLSQMAFQILLRK 3803
+++F +A+E+A E ++ R++ L++SIT +V+ YT + LFE DKLT+L+Q+ FQILL
Sbjct: 3707 SIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFECDKLTYLAQLTFQILLMN 3766
Query: 3804 KEIDPLELDFLLRFTVEHTHLSPVDFLTSQSWSAIKAIAVMEEFRGIDRDVEGSAKQWRK 3863
+E++ +ELDFLLR V+ SPV+FL+ Q+W A+K ++ MEEF +DRD+EGSAK W+K
Sbjct: 3767 REVNAVELDFLLRSPVQTGTASPVEFLSHQAWGAVKVLSSMEEFSNLDRDIEGSAKSWKK 3826
Query: 3864 WVESECPEKEKLPQEWKKKSLIQKLILLRAMRPDRMTYALRNFVEEKLGAKYVERTRLDL 3923
+VESECPEKEKLPQEWK K+ +Q+L +LRAMRPDRMTYALR+FVEEKLG+KYV LD
Sbjct: 3827 FVESECPEKEKLPQEWKNKTALQRLCMLRAMRPDRMTYALRDFVEEKLGSKYVVGRALDF 3886
Query: 3924 VKAFEESSPATPIFFILSPGVDALKDLEILGKRLGFTIDSGKFHNVSLGQGQETVAEVAL 3983
+FEES PATP+FFILSPGVD LKD+E G++LG+T ++ FHNVSLGQGQE VAE AL
Sbjct: 3887 ATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQNFHNVSLGQGQEVVAEAAL 3946
Query: 3984 EKASKGGHWVILQNVHLVAKWLGTLEKLLERFSQGSHRDYRVFMSAESAPTPDEHIIPQG 4043
+ A+K GHWVILQN+HLVAKWL TLEK LE S+ SH ++RVFMSAE AP+P+ HIIPQG
Sbjct: 3947 DLAAKKGHWVILQNIHLVAKWLSTLEKKLEEHSENSHPEFRVFMSAEPAPSPEGHIIPQG 4006
Query: 4044 LLENSIKITNEPPTGMLANLHAALYNFDQDTLEICSKEQEFKSILFSLCYFHACVAGRLR 4103
+LENSIKITNEPPTGM ANLH AL NF QDTLE+CS+E EFKSILF+LCYFHA VA R +
Sbjct: 4007 ILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCSRETEFKSILFALCYFHAVVAERRK 4066
Query: 4104 FGPQGWSRSYPFNPGDLTICASVLYNYLEANSKVPWEDLRYLFGEIMYGGHITDDWDRKL 4163
FGPQGW+RSYPFN GDLTI +VLYN+LEAN+KVP++DLRYLFGEIMYGGHITDDWDR+L
Sbjct: 4067 FGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKVPYDDLRYLFGEIMYGGHITDDWDRRL 4126
Query: 4164 CRVYLEEFMNPSLTEDELMLAPGFAAPPYLDYAGYHQYIEEMLPPESPALYGLHPNAEIE 4223
CR YL EF+ P + E EL LAPGF P +DY GYHQYI+ LPPESP LYGLHPNAEI
Sbjct: 4127 CRTYLGEFIRPEMLEGELSLAPGFPLPGNMDYNGYHQYIDAELPPESPYLYGLHPNAEIG 4186
Query: 4224 FLTVTSNTLFRTLLEMQPRNALSGDELGQSTEEKVKNVLDDILEKLPEEFNMAEIMQKNS 4283
FLT TS LFRT+LE+QPR++ + D G + EEKVK +L++ILE++ +EFN+ E+M K
Sbjct: 4187 FLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVKALLEEILERVTDEFNIPELMAKVE 4246
Query: 4284 NRSPYVLVCFQECERMNILIREIRISLEQLDLSLKGELALSPAVEAQQFALSYDTVPDTW 4343
R+PY++V FQEC RMNIL REI+ SL +L+L LKGEL ++ +E Q AL +D VP++W
Sbjct: 4247 ERTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTSHMENLQNALYFDMVPESW 4306
Query: 4344 SKLAYPSTYGLAQWFNDLLLRCRELDTWTQDLTLPAVVWLSGFFNPQSFLTAIMQTMARK 4403
++ AYPST GLA WF DLL R +EL+ WT D T+P+ VWL+GFFNPQSFLTAIMQ+ ARK
Sbjct: 4307 ARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTGFFNPQSFLTAIMQSTARK 4366
Query: 4404 NEWPLDKTRLTADVTKKTKEDYGHPPREGAYLHGLFMEGARWDTQAGTIVEARLKELACP 4463
NEWPLD+ L D+TKK +E++ PPREGAY+HGLFMEGA WDTQAG I EA+LK+L P
Sbjct: 4367 NEWPLDQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACWDTQAGIITEAKLKDLTPP 4426
Query: 4464 MPVIFAKATPVDRQETKQTYECPVYRTKLRGPSYIWTFRLKSEEKTAKWVLAGVALLLE 4522
MPV+F KA P D+Q+ + Y CPVY+T RGP+Y+WTF LK++E +KWVLAGVALLL+
Sbjct: 4427 MPVMFIKAIPADKQDCRSVYSCPVYKTSQRGPTYVWTFNLKTKENPSKWVLAGVALLLQ 4485
>gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4470
Score = 5330 bits (13827), Expect = 0.0
Identities = 2627/4491 (58%), Positives = 3377/4491 (75%), Gaps = 43/4491 (0%)
Query: 52 SFAQDARVRFLGGRLAMMLGFTEEKWSQYLESEDNRQVLGEFLESTSPACLVFSFAASGR 111
+ A D R+ +L +++L F +KWS+ + +E+N + EF E LV + A+G
Sbjct: 2 TMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAGM 61
Query: 112 LAASQEIPRDANHKLVFISKKITESIGVNDFSQVVLFGELPALSLGHVSAFLDEILVPVL 171
+ P+ K V+ K +E+I +++ +L+G++ + + A ++E+L +L
Sbjct: 62 IIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSLL 121
Query: 172 SNKNNHKSWSCFTSQDMEYHIEVMKKKMYIFRGKMSRRTLLPIPTVAGKMDLDQNCSENK 231
+ N W S+D+ + +K +M++ GK+ +TLLPIP G +D E
Sbjct: 122 NQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMERI 181
Query: 232 PPSNERIILHAIESVVIEWSHQIQEIIERDSVQRLLNGLHLSPQAELDFWMMRRENLSCI 291
P S + ++LHAIE+ +I+WSHQI++++ +DS Q LL+GLH PQ E +FW R NL CI
Sbjct: 182 PSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKCI 241
Query: 292 YDQLQAPVVLKMVKILTTKQSSYFPTLKDIFLAVENALLEAQDVELYLRPLRRHIQCLQE 351
++QL P V K+V+IL +S Y+P L++++ V L EA D+ LYL+PLR ++ +++
Sbjct: 242 HEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEMEQ 301
Query: 352 TEFPQTRILIAPLFHTICLIWSHSKFYNTPARVIVLLQEFCNLFINQATAYLSPEDLLRG 411
+F IA + TIC IW+ S++YNTPAR+IV+LQEFCN I +LSPE++L+G
Sbjct: 302 ADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLKG 361
Query: 412 ---EIEESLEKVQVAVNILKTFKNSFFNYRKKLASYFMGRKLRPWDFQSHLVFCRFDKFL 468
EIEE L + +AVN+LK ++ + +F ++ PW+F S L F R + F
Sbjct: 362 LQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSFF 421
Query: 469 DRLIKIEDIFATTLEFEKLERLEFGGTKGAILNGQVHEMSEELMELCKLFKQSTYDPSDC 528
R+ IE+++ T +EF KLE++E GG +G +L V + +E+ EL K+F YDP D
Sbjct: 422 QRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLDP 481
Query: 529 ------------TNMEFESDYVAFKSKTLEFDRRLGTIICEAFFNCNGLEAAFKLLTIFG 576
+ F+ DY F+ K + DRRL TI C+ F +C+ ++++ KLL + G
Sbjct: 482 GDSVGPRAGLDELDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCG 541
Query: 577 NFLEKPVVMEIFSLHYSTLVHMFNTELDVCKQLYNEHMKQIECGHV-VLNKNMPFTSGNM 635
+E+P+++ + YS ++ +F+ ELD K LY+ M E G++ +++KNMP +G +
Sbjct: 542 GLMERPLILAEVAPRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQL 601
Query: 636 KWAQQVLQRLQMFWSNFASLRYLFLGNPDHALVYQKYVEMTTLLDQFESRIYNEWKSNVD 695
KW+ ++ +RL++ + + + + + L YQKY EM LL +IY +W + VD
Sbjct: 602 KWSLELQERLEVSMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVD 661
Query: 696 EICEFNLNQPLVKFSAINGLLCVNFDPKLVAVLREVKYLLMLKKQDIPDSALAIFKKRNT 755
+ C FNL QPL+ A + L+ VNF LVAVLREVKYL ++++IPDSA ++F + T
Sbjct: 662 QDCHFNLGQPLILRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENET 721
Query: 756 ILKYIGNLDLLVQGYNKLKQTLLEVEYPLIEDELRAIDEQLTAATTWLTWQDD-CWGYIE 814
K++GNL+L+V YN++ + VE+ LI+ EL AID +L +A T L W + + YI+
Sbjct: 722 FRKFVGNLELIVGWYNEVMKA---VEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQ 778
Query: 815 RVRAATSELEHRVERTQKNVKVIQQTMRGWARCVLPPRREHRREAAFTLEDKGDLFTKKY 874
VR L++R+++ ++N++ I Q M+ W+ L R+++++EA L+ + K+Y
Sbjct: 779 EVREILHNLQNRMQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKRY 838
Query: 875 KLIQGDGCKIHNLVEENRKLFKANPSLDTWKIYVEFIDDIVVEGFFQAIMHDLDFFLKNT 934
++ G KI +V EN +LF+A+ WK YV +IDD+V++ F Q I L F + N
Sbjct: 839 AAVRDAGVKIQAMVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDNM 898
Query: 935 EKQLKPAPFFQAQMILLPPEIVFKPSLDREAGDGFYDLVEEMLCNSFRMSAQMNRIATHL 994
AP F+ +M L + F P+L+ + GF L+E ++ + + ++ + R+A
Sbjct: 899 VIDESIAPLFEIRMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAK-- 956
Query: 995 EIKNYQNDMDNMLGLAEVRQEIMNRVVNVINKVLDFRNTLETHTYLWVDDRAEFMKHFLL 1054
+ NY+ D+++ L E+R+E+ + V+N + + +++++ E ++YLW D+ EFMK+FL+
Sbjct: 957 DRMNYKMDLEDNTDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLI 1016
Query: 1055 YGHAVSSDEMDAHANEEIPEQPPTLEQFKEQIDIYEALYVQMSKFEDFRVFDSWFKVDMK 1114
YG AV+++++D ++ IP+ PPTL QF+EQID YE LY ++SK E+ +VF W + D +
Sbjct: 1017 YGCAVTAEDLDTWTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCR 1076
Query: 1115 PFKVSLLTIIKKWSWMFQEHLLRFVIDSLNELQEFIKETDSGLQRELNEGDHDGLVDIMV 1174
PFK +LL+ I++W +MF+ HL V +SL +L+ F+K GL + L EGD+DGLV++M
Sbjct: 1077 PFKQALLSTIRRWGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMG 1136
Query: 1175 HLLAVRSRQRATDELFEPLKETITLLESYGQKMPEQVYIQLEELPERWETTKKIAATVRH 1234
HL+ V+ RQ ATD +FEPLK+TI LL++YG++MPE+++++L+ELPE W TKK+A V+
Sbjct: 1137 HLMKVKERQAATDNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKL 1196
Query: 1235 EVSPLHNAEVTLIRKKCILFDAKQAEFRERFRHYAPLGFNAENPYTALDKANEELEALEE 1294
V+PL EV+++R+KC F+ KQ EFRERFR AP F+ NPY +L+K + + A+E
Sbjct: 1197 TVAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKQQKSISAMEG 1256
Query: 1295 EMLQMQESTRLFEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTKTQWRQIHVE 1354
M + +S LFEV +P+YKQ+K C +E++LLK LWD+++ V SI++W T+W+ I+VE
Sbjct: 1257 IMEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVE 1316
Query: 1355 QMDVELRRFAKASSITEIWSLNKEVRVWDAYTGLEGTVKDMTASLRAITELQSPALRDRH 1414
QMD++ ++FAK ++ SL+KE++ WDA+ GL+ TVK++ SLRA++ELQ+PA+R+RH
Sbjct: 1317 QMDIDCKKFAK-----DMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERH 1371
Query: 1415 WHQLMKAIGVKFLINEATTLADLLALRLHRVEDDVRRIVDKAVKELGTEKVITEISQTWA 1474
W QLM+A VKF ++E TTLADLL L LH ED+VR IVDKAVKE G EKV+ + TW+
Sbjct: 1372 WQQLMQATQVKFKMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWS 1431
Query: 1475 TMKFSYEVHYRTGIPLLKSDEQLFETLEHNQVQLQTLLQSKYVEYFIEQVLSWQNKLNIA 1534
M+F +E H RTG +LKS E L ETLE NQVQLQ L+ SKY+ +F+++V SWQ KL+ A
Sbjct: 1432 MMEFQHEPHPRTGTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTA 1491
Query: 1535 DLVIFTWMEVQRTWSHLESIFVCSEDIRIQLVKDARRFDGVDAEFKELMFKTAKVENVLE 1594
D VI W EVQRTWSHLESIF+ SEDIR QL D++RFD ++ EFK LM K NV+E
Sbjct: 1492 DSVISIWFEVQRTWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVE 1551
Query: 1595 ATCRPNLYEKLKDLQSRLSLCEKALAEYLETKRIAFPRFYFVSSADLLDILSKGAQPKQV 1654
AT +P LY KL+ L+ L++CEKALAEYLETKR+AFPRFYFVSSADLLDILS G P +V
Sbjct: 1552 ATSKPGLYNKLEALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEV 1611
Query: 1655 TCHLAKLFDSIADLQFE-DNQDVSAHRAVGMYSKEKEYVPFQAECECVGHVETWLLQLEQ 1713
+ HL+KLFDS+ L+F D D +GMYSKE EY+ F EC+ G VE WL ++
Sbjct: 1612 SRHLSKLFDSLCKLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLD 1671
Query: 1714 TMQETVRHSITEAIVAYEEKPRELWIFDFPAQVALTSSQIWWTTDVGIAFSRLEEGYETA 1773
M T+RH I EA+V YEEKPRE WI D+PAQVALT +QIWWTT+VG+AF+RLEEGYE A
Sbjct: 1672 RMCSTLRHEIPEAVVTYEEKPREQWILDYPAQVALTCTQIWWTTEVGLAFARLEEGYENA 1731
Query: 1774 LKDFHKKQISQLNTLITLLLGELPPGDRQKIMTICTIDVHARDVVAKLISQKQVVVSPQA 1833
++D++KKQISQLN LITLL+G L GDR KIMTICTIDVHARDVVAK+I K V S QA
Sbjct: 1732 IRDYNKKQISQLNVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMIVAK--VESSQA 1789
Query: 1834 FTWLSQLRHRWEDTQKHCFVNICDAQFQYFYEYLGNSPRLVITPLTDRCYITLTQSLHLT 1893
FTW +QLRHRW++ ++HCF NICDAQ QY YEYLGN+PRLVITPLTDRCYITLTQSLHL
Sbjct: 1790 FTWQAQLRHRWDEEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLI 1849
Query: 1894 MSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGAWGCFDE 1953
M GAPAGPAGTGKTETTKDLGRALG MVYVFNCSEQMDYKS GNIYKGL QTGAWGCFDE
Sbjct: 1850 MGGAPAGPAGTGKTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDE 1909
Query: 1954 FNRISVEVLSVVAVQVKMIHDAIRNRKKRFVFLGEAITLKPSVGIFITMNPGYAGRTELP 2013
FNRISVEVLSV+AVQVK + DAIR +KK F FLGE I L P+VGIFITMNPGYAGR ELP
Sbjct: 1910 FNRISVEVLSVIAVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELP 1969
Query: 2014 ENLKALFRPCAMVAPDIELICEILLVAEGFVDARALARKFITLYTLCKELLSKQDHYDWG 2073
ENLKALFRPCAMV PD ELICEI+L+AEGF++AR LARKFITLYTLCKELLSKQDHYDWG
Sbjct: 1970 ENLKALFRPCAMVVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWG 2029
Query: 2074 LRAIKSVLVVAGSLKRGDKNRPEDQVLMRALRDFNMPKIVTDDIPVFLGLVGDLFPALDV 2133
LRAIKSVLVVAGSLKRGD +R EDQVLMRALRDFN+PKIVTDD+PVF+GL+GDLFPALDV
Sbjct: 2030 LRAIKSVLVVAGSLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDV 2089
Query: 2134 PRRRKLHFEQMVRQSTLELRLQPEESFILKVVQLEELLAVRHSVFVVGNAGTGKSKILRT 2193
PR+R L+FE++++QS +EL+LQ E+SF+LKVVQLEELL VRHSVF+VGNAG+GKS++L++
Sbjct: 2090 PRKRDLNFEKIIKQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKS 2149
Query: 2194 LNRTYVNMKQKPVWNDLNPKAVTTDELFGFIHHATREWKDGKIVYSYFIGLFSSILREQA 2253
LN+TY N+K+KPV DL+PKAVT DELFG I+ TREWKDG LFS+I+R+ A
Sbjct: 2150 LNKTYQNLKRKPVAVDLDPKAVTCDELFGIINPVTREWKDG---------LFSTIMRDLA 2200
Query: 2254 NLKHDGPKWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIALTPFMRLLFEIHHLRSA 2313
N+ HDGPKWI+LDGDIDPMWIESLNTVMDDNKVLTLASNERI L MRL+FEI HLR+A
Sbjct: 2201 NITHDGPKWIILDGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTA 2260
Query: 2314 TPATVSRAGILYVNPQDLGWNPYVASWIDRRRHQSEKANLTILFDKYVPACLDKLRTSFK 2373
TPATVSRAGILY+NP DLGWNP V+SWI+RR+ QSEKANL ILFDKY+P CLDKLR FK
Sbjct: 2261 TPATVSRAGILYINPADLGWNPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFK 2320
Query: 2374 TITSIPESSLVQTLCVLLECLLTPENVPSDSPKEVYEVYFVFACIWAFGGTLLQDQISDY 2433
IT +PE +++QT+ LLECLLT + VP DSP+E+YE+YFVF C WAFGG + QDQ+ DY
Sbjct: 2321 KITPVPEITVIQTILYLLECLLTEKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDY 2380
Query: 2434 QADFSRWWQKEMKAVKFPSQGTIFDYYVDHKTKKLLPWADKIAQFTMDPDVPLQTVLVHT 2493
+ +FS+WW E K +KFPSQGTIFDYY+D TKK LPW DK+ F +DPDVPLQ LVHT
Sbjct: 2381 RVEFSKWWINEFKTIKFPSQGTIFDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHT 2440
Query: 2494 TETARLRYFMELLLEKGKPLMLVGNAGVGKTVFVGDTLASLSED-YIVSRVPFNYYTTST 2552
TET R+RYFM+LL+EK P+MLVGNAG GK+V +GD L SL+ D Y+V VPFN+YTTS
Sbjct: 2441 TETIRIRYFMDLLMEKSWPVMLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSA 2500
Query: 2553 ALQKILEKPLEKKAGHNYGPGGNKKLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWY 2612
LQ +LEKPLEKK+G NYGP G KKL+YFIDDMNMPEVD YGTV PHTLIRQH+D+ HWY
Sbjct: 2501 MLQGVLEKPLEKKSGRNYGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWY 2560
Query: 2613 DRQKVMLKEIHNCQYVACMNPMVGSFTINPRLQRHFTVFAFNFPSLDALNTIYGQIFSFH 2672
DR K+ LK+IHNCQYVACMNP GSFTI+ RLQRHF VFA +FP +AL TIY I + H
Sbjct: 2561 DRHKLTLKDIHNCQYVACMNPTSGSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQH 2620
Query: 2673 FQQQAFAPSILRSGPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFASP 2732
++ + +I R L+ A +A HQ + FLPTAIKFHY+FNLRDLSN+FQG+LF++
Sbjct: 2621 LAFRSVSMAIQRISSQLVAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTA 2680
Query: 2733 ECLKGPLDLIHLWLHESARVYGDKLIDKKDCDLFQRRMLETAYKYFEGIDSHMLLQQPLI 2792
E LK PLDL+ LWLHE+ RVYGDK++D+KD + R + + K+F+ + +L +P I
Sbjct: 2681 EVLKTPLDLVRLWLHETERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNI 2740
Query: 2793 YCHFADRGKDPHYMPVKDWEVLKTILTETLDNYNELNAAMHLVLFEDAMQHVCRISRILR 2852
+CHFA DP Y+PV D L +L + LD+YNE+NA M+LVLFEDA+ H+CRI+RIL
Sbjct: 2741 FCHFAQGIGDPKYVPVTDMAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILE 2800
Query: 2853 TPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYGIQELRVDLANLYIRTGAKN 2912
+P+G ALLVGVGGSGKQSLSRLAAY+ GL+VFQITL +GYGI +L++DLA YI+ KN
Sbjct: 2801 SPRGNALLVGVGGSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKN 2860
Query: 2913 MPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDKIISGIHNEVHALGMVDSRE 2972
+P+VFL+TD+QV +E FLVLINDLLASGEIP LF +++V+ IIS + +V +LGM D+RE
Sbjct: 2861 VPSVFLMTDSQVAEEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRE 2920
Query: 2973 NCWKFFMARVRLQLKIILCFSPVGRTLRVRARKFPAIVNCTAIDWFHAWPQEALVSVSRR 3032
CWKFF+ +VR QLK+ILCFSPVG LRVRARKFPA+VNCTAIDWFH WP++ALVSVS R
Sbjct: 2921 TCWKFFIEKVRRQLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSAR 2980
Query: 3033 FIEETKGIEPVHKDSISLFMAHVHTTVNEMSTRYYQNERRHNYTTPKSFLEQISLFKNLL 3092
F+EET+GI PV K SIS FM++VHTTVNEMS Y ERR+NYTTPK+FLEQI L++NLL
Sbjct: 2981 FLEETEGI-PVIKASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLL 3039
Query: 3093 KKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLASQEAELQLRNHDAEALITKIGLQT 3152
KK+ E+ K ERL NG+ KL++TASQV DLKA+LA QEAEL+ +N A+ LI +G++
Sbjct: 3040 AKKRTELVAKIERLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEA 3099
Query: 3153 EKVSREKTIADAEERKVTAIQTEVFQKQRECEADLLKAEPALVAATAALNTLNRVNLSEL 3212
EKVS+EK IAD EE KV I V +KQ+ CE DL KAEPAL+AA AL+TLN+ NL+EL
Sbjct: 3100 EKVSKEKAIADQEEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTEL 3159
Query: 3213 KAFPNPPIAVTNVTAAVMVLLAPRGRVPKDRSWKAAKVFMGKVDDFLQALINYDKEHIPE 3272
K+F +PP AV NVTAAVM+L AP G++PKD+SWKAAK+ MGKVD FL +L +DKEHIPE
Sbjct: 3160 KSFGSPPDAVVNVTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPE 3219
Query: 3273 NCLKVVNEHYLKDPEFNPNLIRTKSFAAAGLCAWVINIIKFYEVYCDVEPKRQALAQANL 3332
CLK Y +P F+P IR+KS AAAGLC+W INI++FYEVYCDV PKRQAL +AN
Sbjct: 3220 ACLKAFKP-YQGNPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANA 3278
Query: 3333 ELAAATEKLEAIRKKLVDLDRNLSRLTASFEKATAEKVRCQEEVNQTNKTIKLANRLVKE 3392
ELA A EKL I+ K+ +L+ NLS LT++FEKATAEK++CQ+E + TN+ I LANRLV
Sbjct: 3279 ELAEAQEKLSRIKNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGG 3338
Query: 3393 LEAKKIRWGQSIKSFEAQEKTLCGDVLLTAAFVSYVGPFTRQYRQELVHCKWVPFLQQ-K 3451
L ++ IRW +S+++F +Q TLCGDVLL +AFVSYVG FT++YR EL+ W+P++ K
Sbjct: 3339 LASENIRWAESVENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLK 3398
Query: 3452 VSIPLTEGLDLISMLTDDATIAAWNNEGLPSDRMSTENAAILTHCERWPLVIDPQQQGIK 3511
V IP+T GLD +S+LTDDA +A WNN+GLPSDRMSTENA IL + ERWPL++D Q QGIK
Sbjct: 3399 VPIPITNGLDPLSLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIK 3458
Query: 3512 WIKNKYGMDLKVTHLGQKGFLNAIETALAFGDVILIENLEETIDPVLDPLLGRNTIKKGK 3571
WIKNKY +LK LGQK +L+ IE A++ GD +LIEN+ ET+DPVLDPLLGRNTIKKGK
Sbjct: 3459 WIKNKYRSELKAIRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGK 3518
Query: 3572 YIRIGDKECEFNKNFRLILHTKLANPHYKPELQAQTTLLNFTVTEDGLEAQLLAEVVSIE 3631
YI+IGDKE E++ FRLILHTK NPHYKPE+QAQ TL+NF VT DGLE QLLA VV+ E
Sbjct: 3519 YIKIGDKEVEYHPKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKE 3578
Query: 3632 RPDLEKLKLVLTKHQNDFKIELKYLEDDLLLRLSAAEGSFLDDTKLVERLEATKTTVAEI 3691
RPDLE+LK LTK QN+FKI LK LED LL RLSAA G+FL DT LVE LE TK T +EI
Sbjct: 3579 RPDLEQLKANLTKSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEI 3638
Query: 3692 EHKVIEAKENERKINEARECYRPVAARASLLYFVINDLQKINPLYQFSLKAFNVLFHRAI 3751
E KV+EAK E KINEARE YRP A RASLLYF++NDL KINP+YQFSLKAFNV+F +AI
Sbjct: 3639 EEKVVEAKITEVKINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAI 3698
Query: 3752 EQADKVEDMQGRISILMESITHAVFLYTSQALFEKDKLTFLSQMAFQILLRKKEIDPLEL 3811
++ +++ R+ L + IT++V++YT++ LFE+DKL FL+Q+ FQ+L KKE++P+EL
Sbjct: 3699 QRTTPANEVKQRVINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVEL 3758
Query: 3812 DFLLRFTVEHTHLSPVDFLTSQSWSAIKAIAVMEEFRGIDRDVEGSAKQWRKWVESECPE 3871
DFLLRF + +SPVDFL Q W IKA++ M+EF+ +D D+EGSAK+W+K VESE PE
Sbjct: 3759 DFLLRFPFKAGVVSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPE 3818
Query: 3872 KEKLPQEWKKKSLIQKLILLRAMRPDRMTYALRNFVEEKLGAKYVERTRLDLVKAFEESS 3931
KE P+EWK K+ +QKL ++R +RPDRMTYA++NFVEEK+G+K+VE ++ K++EESS
Sbjct: 3819 KEIFPKEWKNKTALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESS 3878
Query: 3932 PATPIFFILSPGVDALKDLEILGKRLGFTIDSGKFHNVSLGQGQETVAEVALEKASKGGH 3991
P+T IFFILSPGVD LKD+E LGK+LGFTID+GK HNVSLGQGQE VAE AL+ A++ GH
Sbjct: 3879 PSTSIFFILSPGVDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGH 3938
Query: 3992 WVILQNVHLVAKWLGTLEKLLERFSQGSHRDYRVFMSAESAPTPDEHIIPQGLLENSIKI 4051
WVILQN+HLVA+WLGTL+K LER+S GSH DYRVF+SAE AP+P+ HIIPQG+LEN+IKI
Sbjct: 3939 WVILQNIHLVARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKI 3998
Query: 4052 TNEPPTGMLANLHAALYNFDQDTLEICSKEQEFKSILFSLCYFHACVAGRLRFGPQGWSR 4111
TNEPPTGM ANLH AL F QDTLE+C+KE EFK +LF+LCYFHA VA R +FG QGW+R
Sbjct: 3999 TNEPPTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNR 4058
Query: 4112 SYPFNPGDLTICASVLYNYLEANSKVPWEDLRYLFGEIMYGGHITDDWDRKLCRVYLEEF 4171
SYPFN GDLTI +VLYNYLEAN KVPW+DLRYLFGEIMYGGHITDDWDR+LCR YL E+
Sbjct: 4059 SYPFNNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEY 4118
Query: 4172 MNPSLTEDELMLAPGFAAPPYLDYAGYHQYIEEMLPPESPALYGLHPNAEIEFLTVTSNT 4231
+ + E +++LAPGF PP LDY GYH+YI+E LPPESP LYGLHPNAEI FLTVTS
Sbjct: 4119 IRTEMLEGDVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEK 4178
Query: 4232 LFRTLLEMQPRNALSGDELGQSTEEKVKNVLDDILEKLPEEFNMAEIMQKNSNRSPYVLV 4291
LFRT+LEMQP+ SG G S EEKVK VLDDILEK+PE FNMAEIM K + ++PYV+V
Sbjct: 4179 LFRTVLEMQPKETDSGAGTGVSREEKVKAVLDDILEKIPETFNMAEIMAKAAEKTPYVVV 4238
Query: 4292 CFQECERMNILIREIRISLEQLDLSLKGELALSPAVEAQQFALSYDTVPDTWSKLAYPST 4351
FQECERMNIL E+R SL++L+L LKGEL ++ VE AL YDTVPDTW AYPS
Sbjct: 4239 AFQECERMNILTNEMRRSLKELNLGLKGELTITTDVEDLSTALFYDTVPDTWVARAYPSM 4298
Query: 4352 YGLAQWFNDLLLRCRELDTWTQDLTLPAVVWLSGFFNPQSFLTAIMQTMARKNEWPLDKT 4411
GLA W+ DLLLR REL+ WT D LP VWL+GFFNPQSFLTAIMQ+MARKNEWPLDK
Sbjct: 4299 MGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGFFNPQSFLTAIMQSMARKNEWPLDKM 4358
Query: 4412 RLTADVTKKTKEDYGHPPREGAYLHGLFMEGARWDTQAGTIVEARLKELACPMPVIFAKA 4471
L+ +VTKK +ED PPREG+Y++GLFMEGARWDTQ G I EARLKEL MPVIF KA
Sbjct: 4359 CLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWDTQTGVIAEARLKELTPAMPVIFIKA 4418
Query: 4472 TPVDRQETKQTYECPVYRTKLRGPSYIWTFRLKSEEKTAKWVLAGVALLLE 4522
PVDR ETK YECPVY+T++RGP+Y+WTF LK++EK AKW+LA VALLL+
Sbjct: 4419 IPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTKEKAAKWILAAVALLLQ 4469
>gi|239751459 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 5294 bits (13732), Expect = 0.0
Identities = 2620/4516 (58%), Positives = 3367/4516 (74%), Gaps = 78/4516 (1%)
Query: 52 SFAQDARVRFLGGRLAMMLGFTEEKWSQYLESEDNRQVLGEFLESTSPACLVFSFAASGR 111
+ A D R+ +L +++L F +KWS+ + +E+N + EF E LV + A+G
Sbjct: 2 TMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAGM 61
Query: 112 LAASQEIPRDANHKLVFISKKITESIGVNDFSQVVLFGELPALSLGHVSAFLDEILVPVL 171
+ P+ K V+ K +E+I +++ +L+G++ + + A ++E+L +L
Sbjct: 62 IIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSLL 121
Query: 172 SNKNNHKSWSCFTSQDMEYHIEVMKKKMYIFRGKMSRRTLLPIPTVAGKMDLDQNCSENK 231
+ N W S+D+ + +K +M++ GK+ +TLLPIP G +D E
Sbjct: 122 NQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMERI 181
Query: 232 PPSNERIILHAIESVVIEWSHQIQEIIERDSVQRLLNGLHLSPQAELDFWMMRRENLSCI 291
P S + ++LHAIE+ +I+WSHQI++++ +DS Q LL+GLH PQ E +FW R NL CI
Sbjct: 182 PSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDARLLNLKCI 241
Query: 292 YDQLQAPVVLKMVKILTTKQSSYFPTLKDIFLAVENALLEAQDVELYLRPLRRHIQCLQE 351
++QL P V K+V+IL +S Y+P L++++ V L EA D+ LYL+PLR ++ +++
Sbjct: 242 HEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEMEQ 301
Query: 352 TEFPQTRILIAPLFHTICLIWSHSKFYNTPARVIVLLQEFCNLFINQATAYLSPEDLLRG 411
+F IA + TIC IW+ S++YNTPAR+IV+LQEFCN I +LSPE++L+G
Sbjct: 302 ADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLKG 361
Query: 412 ---EIEESLEKVQVAVNILKTFKNSFFNYRKKLASYFMGRKLRPWDFQSHLVFCRFDKFL 468
EIEE L + +AVN+LK ++ + +F ++ PW+F S L F R + F
Sbjct: 362 LQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSFF 421
Query: 469 DRLIKIEDIFATTLEFEKLERLEFGGTKGAILNGQVHEMSEELMELCKLFKQSTYDPSDC 528
R+ IE+++ T +EF KLE++E GG +G +L V + +E+ EL K+F YDP D
Sbjct: 422 QRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLDP 481
Query: 529 TNMEFESDYVAFKSKTLEFDRRLGTIICEAFFNCNGLEAAFKLLTIFGNFLEKPVVMEIF 588
+ F+ DY F+ K + DRRL TI C+ F +C+ ++++ KLL + G +E+P+++
Sbjct: 482 GDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLILAEV 541
Query: 589 SLHYSTLVHMFNTELDVCKQLYNEHMKQIECGHV-VLNKNMPFTSGNMKWAQQVLQRLQM 647
+ YS ++ +F+ ELD K LY+ M E G++ +++KNMP +G +KW+ ++ +RL++
Sbjct: 542 APRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQERLEV 601
Query: 648 FWSNFASLRYLFLGNPDHALVYQKYVEMTTLLDQFESRIYNEWKSNVDEICEFNLNQPLV 707
+ + + + + L YQKY EM LL +IY +W + VD+ C FNL QPL+
Sbjct: 602 SMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNLGQPLI 661
Query: 708 KFSAINGLLCVNFDPKLVAVLREVKYLLMLKKQDIPDSALAIFKKRNTILKYIGNLDLLV 767
A + L+ VNF LVAVLREVKYL ++++IPDSA ++F + T K++GNL+L+V
Sbjct: 662 LRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNLELIV 721
Query: 768 QGYNKLKQTLLEVEYPLIEDELRAIDEQLTAATTWLTWQDD-CWGYIERVRAATSELEHR 826
YN++K + VE+ LI+ EL AID +L +A T L W + + YI+ VR L++R
Sbjct: 722 GWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQNR 781
Query: 827 VERTQKNVKVIQQTMRGWARCVLPPRREHRREAAFTLEDKGDLFTKKYKLIQGDGCKIHN 886
+++ ++N++ I Q M+ W+ L R+++++EA L+ + K+Y ++ G KI
Sbjct: 782 MQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKRYAAVRDAGVKIQA 841
Query: 887 LVEENRKLFKANPSLDTWKIYVEFIDDIVVEGFFQAIMHDLDFFLKNTEKQLKPAPFFQA 946
+V EN +LF+A+ WK YV +IDD+V++ F Q I L F + N AP F+
Sbjct: 842 MVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDNMVIDESIAPLFEI 901
Query: 947 QMILLPPEIVFKPSLDREAGDGFYDLVEEMLCNSFRMSAQMNRIATHLEIKNYQNDMDNM 1006
+M L + F P+L+ + GF L+E ++ + + ++ + R+A + NY+ D+++
Sbjct: 902 RMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAK--DRMNYKMDLEDN 959
Query: 1007 LGLAEVRQEIMNRVVNVINKVLDFRNTLETHTYLWVDDRAEFMKHFLLYGHAVSSDEMDA 1066
L E+R+E+ + V+N + + +++++ E ++YLW D+ EFMK+FL+YG AV+++++D
Sbjct: 960 TDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDT 1019
Query: 1067 HANEEIPEQPPTLEQFKEQIDIYEALYVQMSKFEDFRVFDSWFKVDMKPFKVSLLTIIKK 1126
++ IP+ PPTL QF+EQID YE LY ++SK E+ +VF W + D +PFK +LL+ I++
Sbjct: 1020 WTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRR 1079
Query: 1127 WSWMFQEHLLRFVIDSLNELQEFIKETDSGLQRELNEGDHDGLVDIMVHLLAVRSRQRAT 1186
W +MF+ HL V +SL +L+ F+K GL + L EGD+DGLV++M HL+ V+ RQ AT
Sbjct: 1080 WGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAAT 1139
Query: 1187 DELFEPLKETITLLESYGQKMPEQVYIQLEELPERWETTKKIAATVRHEVSPLHNAEVTL 1246
D +FEPLK+TI LL++YG++MPE+++++L+ELPE W TKK+A V+ V+PL EV++
Sbjct: 1140 DNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSI 1199
Query: 1247 IRKKCILFDAKQAEFRERFRHYAPLGFNAENPYTALDKANEELEALEEEMLQMQESTRLF 1306
+R+KC F+ KQ EFRERFR AP F+ NPY +L+K + L+ M + +S LF
Sbjct: 1200 LRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNK----VFLLKGIMEALSKSGGLF 1255
Query: 1307 EVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTKTQWRQIHVEQMDVELRRFAKA 1366
EV +P+YKQ+K C +E++LLK LWD+++ V SI++W T+W+ I+VEQMD++ ++FAK
Sbjct: 1256 EVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAK- 1314
Query: 1367 SSITEIWSLNKEVRVWDAYTGLEGTVKDMTASLRAITELQSPALRDRHWHQLMKAIGVKF 1426
++ SL+KE++ WDA+ GL+ TVK++ SLRA++ELQ+PA+R+RHW QLM+A VKF
Sbjct: 1315 ----DMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKF 1370
Query: 1427 LINEATTLADLLALRLHRVEDDVRRIVDKAVKELGTEKVITEISQTWATMKFSYEVHYRT 1486
++E TTLADLL L LH ED+VR IVDKAVKE G EKV+ + TW+ M+F +E H RT
Sbjct: 1371 KMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRT 1430
Query: 1487 GIPLLKSDEQLFETLEHNQVQLQTLLQSKYVEYFIEQVLSWQNKLNIADLVIFTWMEVQR 1546
G +LKS E L ETLE NQVQLQ L+ SKY+ +F+++V SWQ KL+ AD VI W EVQR
Sbjct: 1431 GTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQR 1490
Query: 1547 TWSHLESIFVCSEDIRIQLVKDARRFDGVDAEFKELMFKTAKVENVLEATCRPNLYEKLK 1606
TWSHLESIF+ SEDIR QL D++RFD ++ EFK LM K NV+EAT +P LY KL+
Sbjct: 1491 TWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLE 1550
Query: 1607 DLQSRLSLCEKALAEYLETKRIAFPRFYFVSSADLLDILSKGAQPKQVTCHLAKLFDSIA 1666
L+ L++CEKALAEYLETKR+AFPRFYFVSSADLLDILS G P +V+ HL+KLFDS+
Sbjct: 1551 ALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLC 1610
Query: 1667 DLQFE-DNQDVSAHRAVGMYSKEKEYVPFQAECECVGHVETWLLQLEQTMQETVRHSITE 1725
L+F D D +GMYSKE EY+ F EC+ G VE WL ++ M T+RH I E
Sbjct: 1611 KLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPE 1670
Query: 1726 AIVAYEEKPRELWIFDFPAQVALTSSQIWWTTDVGIAFSRLEEGYETALKDFHKKQISQL 1785
A+V YEEKPRE WI D+PAQ IWWTT+VG+AF+RLEEGYE A+KD++KKQISQL
Sbjct: 1671 AVVTYEEKPREQWILDYPAQ-------IWWTTEVGLAFARLEEGYENAIKDYNKKQISQL 1723
Query: 1786 NTLITLLLGELPPGDRQKIMTICTIDVHARDVVAKLISQKQVVVSPQAFTWLSQLRHRWE 1845
N LITLL+G L GDR KIMTICTIDVHARDVVAK+I V S QAFTW +QLRHRW+
Sbjct: 1724 NVLITLLIGNLNAGDRMKIMTICTIDVHARDVVAKMI-----VESSQAFTWQAQLRHRWD 1778
Query: 1846 DTQKHCFVNICDAQFQYFYEYLGNSPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTG 1905
+ ++HCF NICDAQ QY YEYLGN+PRLVITPLTDRCYITLTQSLHL M GAPAGPAGTG
Sbjct: 1779 EEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTG 1838
Query: 1906 KTETTKDLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGAWGCFDEFNRISVEVLSVV 1965
KTETTKDLGRALG MVYVFNCSEQMDYKS GNIYKGL QTGAWGCFDEFNRISVEVLSV+
Sbjct: 1839 KTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVI 1898
Query: 1966 AVQVKMIHDAIRNRKKRFVFLGEAITLKPSVGIFITMNPGYAGRTELPENLKALFRPCAM 2025
AVQVK + DAIR +KK F FLGE I L P+VGIFITMNPGYAGR ELPENLKALFRPCAM
Sbjct: 1899 AVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAM 1958
Query: 2026 VAPDIELICEILLVAEGFVDARALARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAG 2085
V PD ELICEI+L+AEGF++AR LARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAG
Sbjct: 1959 VVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAG 2018
Query: 2086 SLKRGDKNRPEDQVLMRALRDFNMPKIVTDDIPVFLGLVGDLFPALDVPRRRKLHFEQMV 2145
SLKRGD +R EDQVLMRALRDFN+PKIVTDD+PVF+GL+GDLFPALDVPR+R L+FE+++
Sbjct: 2019 SLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKII 2078
Query: 2146 RQSTLELRLQPEESFILKVVQLEELLAVRHSVFVVGNAGTGKSKILRTLNRTYVNMKQKP 2205
+QS +EL+LQ E+SF+LKVVQLEELL VRHSVF+VGNAG+GKS++L++LN+TY N+K+KP
Sbjct: 2079 KQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKP 2138
Query: 2206 VWNDLNPKAVTTDELFGFIHHATREWKDGKIVYSYFIGLFSSILREQANLKHDGPKWIVL 2265
V DL+PKAVT DELFG I+ TREWKDG LFS+I+R+ AN+ HDGPKWI+L
Sbjct: 2139 VAVDLDPKAVTCDELFGIINPVTREWKDG---------LFSTIMRDLANITHDGPKWIIL 2189
Query: 2266 DGDIDPMWIESLNTVMDDNKVLTLASNERIALTPFMRLLFEIHHLRSATPATVSRAGILY 2325
DGDIDPMWIESLNTVMDDNKVLTLASNERI L MRL+FEI HLR+ATPATVSRAGILY
Sbjct: 2190 DGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILY 2249
Query: 2326 VNPQDLGWNPYVASWIDRRRHQSEKANLTILFDKYVPACLDKLRTSFKTITSIPESSLVQ 2385
+NP DLGWNP V+SWI+RR+ QSEKANL ILFDKY+P CLDKLR FK IT +PE +++Q
Sbjct: 2250 INPADLGWNPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQ 2309
Query: 2386 TLCVLLECLLTPENVPSDSPKEVYEVYFVFACIWAFGGTLLQDQISDYQADFSRWWQKEM 2445
T+ LLECLLT + VP DSP+E+YE+YFVF C WAFGG + QDQ+ DY+ +FS+WW E
Sbjct: 2310 TILYLLECLLTEKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEF 2369
Query: 2446 KAVKFPSQGTIFDYYVDHKTKKLLPWADKIAQFTMDPDVPLQTVLVHTTETARLRYFMEL 2505
K +KFPSQGTIFDYY+D TKK LPW DK+ F +DPDVPLQ LVHTTET R+RYFM+L
Sbjct: 2370 KTIKFPSQGTIFDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDL 2429
Query: 2506 LLEKGKPLMLVGNAGVGKTVFVGDTLASLSED-YIVSRVPFNYYTTSTALQKILEKPLEK 2564
L+EK P+MLVGNAG GK+V +GD L SL+ D Y+V VPFN+YTTS LQ +LEKPLEK
Sbjct: 2430 LMEKSWPVMLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEK 2489
Query: 2565 KAGHNYGPGGNKKLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYDRQKVMLKEIHN 2624
K+G NYGP G KKL+YFIDDMNMPEVD YGTV PHTLIRQH+D+ HWYDR K+ LK+IHN
Sbjct: 2490 KSGRNYGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHN 2549
Query: 2625 CQYVACMNPMVGSFTINPRLQRHFTVFAFNFPSLDALNTIYGQIFSFHFQQQAFAPSILR 2684
CQYVACMNP GSFTI+ RLQRHF VFA +FP +AL TIY I + H ++ + +I R
Sbjct: 2550 CQYVACMNPTSGSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQR 2609
Query: 2685 SGPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFASPECLKGPLDLIHL 2744
L+ A +A HQ + FLPTAIKFHY+FNLRDLSN+FQG+LF++ E LK PLDL+ L
Sbjct: 2610 ISSQLVAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRL 2669
Query: 2745 WLHESARVYGDKLIDKKDCDLFQRRMLETAYKYFEGIDSHMLLQQPLIYCHFADRGKDPH 2804
WLHE+ RVYGDK++D+KD + R + + K+F+ + +L +P I+CHFA DP
Sbjct: 2670 WLHETERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPK 2729
Query: 2805 YMPVKDWEVLKTILTETLDNYNELNAAMHLVLFEDAMQHVCRISRILRTPQGCALLVGVG 2864
Y+PV D L +L + LD+YNE+NA M+LVLFEDA+ H+CRI+RIL +P+G ALLVGVG
Sbjct: 2730 YVPVTDMAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVG 2789
Query: 2865 GSGKQSLSRLAAYLRGLEVFQITLTEGYGIQELRVDLANLYIRTGAKNMPTVFLLTDAQV 2924
GSGKQSLSRLAAY+ GL+VFQITL +GYGI +L++DLA YI+ KN+P+VFL+TD+QV
Sbjct: 2790 GSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQV 2849
Query: 2925 LDESFLVLINDLLASGEIPDLFSDEDVDKIISGIHNEVHALGMVDSRENCWKFFMARVRL 2984
+E FLVLINDLLASGEIP LF +++V+ IIS + +V +LGM D+RE CWKFF+ +VR
Sbjct: 2850 AEEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRR 2909
Query: 2985 QLKIILCFSPVGRTLRVRARKFPAIVNCTAIDWFHAWPQEALVSVSRRFIEETKGIEPVH 3044
QLK+ILCFSPVG LRVRARKFPA+VNCTAIDWFH WP++ALVSVS RF+EET+GI
Sbjct: 2910 QLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEV 2969
Query: 3045 KDSISLFMAHVHTTVNEMSTRYYQNERRHNYTTPKSFLEQISLFKNLLKKKQNEVSEKKE 3104
K SIS FM++VHTTVNEMS Y ERR+NYTTPK+FLEQI L++NLL KK+ E+ K E
Sbjct: 2970 KASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIE 3029
Query: 3105 RLVNGIQKLKTTASQVGDLKARLASQEAELQLRNHDAEALITKIGLQTEKVSREKTIADA 3164
RL NG+ KL++TASQV DLKA+LA QEAEL+ +N A+ LI +G++ EKVS+EK IAD
Sbjct: 3030 RLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQ 3089
Query: 3165 EERKVTAIQTEVFQKQRECEADLLKAEPALVAATAALNTLNRVNLSELKAFPNPPIAVTN 3224
EE KV I V +KQ+ CE DL KAEPAL+AA AL+TLN+ NL+ELK+F +PP AV N
Sbjct: 3090 EEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVN 3149
Query: 3225 VTAAVMVLLAPRGRVPKDRSWKAAKVFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLK 3284
VTAAVM+L AP G++PKD+SWKAAK+ MGKVD FL +L +DKEHIPE CLK Y
Sbjct: 3150 VTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKP-YQG 3208
Query: 3285 DPEFNPNLIRTKSFAAAGLCAWVINIIKFYEVYCDVEPKRQALAQANLELAAATEKLEAI 3344
+P F+P IR+KS AAAGLC+W INI++FYEVYCDV PKRQAL +AN ELA A EKL I
Sbjct: 3209 NPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRI 3268
Query: 3345 RKKLVDLDRNLSRLTASFEKATAEKVRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSI 3404
+ K+ +L+ NLS LT++FEKATAEK++CQ+E + TN+ I LANRLV L ++ IRW +S+
Sbjct: 3269 KNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESV 3328
Query: 3405 KSFEAQEKTLCGDVLLTAAFVSYVGPFTRQYRQELVHCKWVPFLQQ-KVSIPLTEGLDLI 3463
++F +Q TLCGDVLL +AFVSYVG FT++YR EL+ W+P++ KV IP+T GLD +
Sbjct: 3329 ENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPL 3388
Query: 3464 SMLTDDATIAAWNNEGLPSDRMSTENAAILTHCERWPLVIDPQQQGIKWIKNKYGMDLKV 3523
S+LTDDA +A WNN+GLPSDRMSTENA IL + ERWPL++D Q QGIKWIKNKY +LK
Sbjct: 3389 SLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKA 3448
Query: 3524 THLGQKGFLNAIETALAFGDVILIENLEETIDPVLDPLLGRNTIKKGKYIRIGDKECEFN 3583
LGQK +L+ IE A++ GD +LIEN+ ET+DPVLDPLLGRNTIKKGKYI+IGDKE E++
Sbjct: 3449 IRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYH 3508
Query: 3584 KNFRLILHTKLANPHYKPELQAQTTLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLT 3643
FRLILHTK NPHYKPE+QAQ TL+NF VT DGLE QLLA VV+ ERPDLE+LK LT
Sbjct: 3509 PKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLT 3568
Query: 3644 KHQNDFKIELKYLEDDLLLRLSAAEGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENER 3703
K QN+FKI LK LED LL RLSAA G+FL DT LVE LE TK T +EIE KV+EAK E
Sbjct: 3569 KSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEV 3628
Query: 3704 KINEARECYRPVAARASLLYFVINDLQKINPLYQFSLKAFNVLFHRAIEQADKVEDMQGR 3763
KINEARE YRP A RASLLYF++NDL KINP+YQFSLKAFNV+F +AI++ +++ R
Sbjct: 3629 KINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQR 3688
Query: 3764 ISILMESITHAVFLYTSQALFEKDKLTFLSQMAFQILLRKKEIDPLELDFLLRFTVEHTH 3823
+ L + IT++V++YT++ LFE+DKL FL+Q+ FQ+L KKE++P+ELDFLLRF +
Sbjct: 3689 VINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGV 3748
Query: 3824 LSPVDFLTSQSWSAIKAIAVMEEFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKKS 3883
+SPVDFL Q W IKA++ M+EF+ +D D+EGSAK+W+K VESE PEKE P+EWK K+
Sbjct: 3749 VSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKT 3808
Query: 3884 LIQKLILLRAMRPDRMTYALRNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPG 3943
+QKL ++R +RPDRMTYA++NFVEEK+G+K+VE ++ K++EESSP+T IFFILSPG
Sbjct: 3809 ALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPG 3868
Query: 3944 VDALKDLEILGKRLGFTIDSGKFHNVSLGQGQETVAEVALEKASKGGHWVILQ------- 3996
VD LKD+E LGK+LGFTID+GK HNVSLGQGQE VAE AL+ A++ GHWVILQ
Sbjct: 3869 VDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQVRGGQHC 3928
Query: 3997 -NVHLVAKWLGTLEKLLERFSQGSHRDYRVFMSAESAPTPDEHIIPQGLLENSIKITNEP 4055
N+HLVA+WLGTL+K LER+S GSH DYRVF+SAE AP+P+ HIIPQG+LEN+IKITNEP
Sbjct: 3929 RNIHLVARWLGTLDKKLERYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEP 3988
Query: 4056 PTGMLANLHAALYNFDQDTLEICSKEQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPF 4115
PTGM ANLH AL F QDTLE+C+KE EFK +LF+LCYFHA VA R +FG QGW+RSYPF
Sbjct: 3989 PTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPF 4048
Query: 4116 NPGDLTICASVLYNYLEANSKVPWEDLRYLFGEIMYGGHITDDWDRKLCRVYLEEFMNPS 4175
N GDLTI +VLYNYLEAN KVPW+DLRYLFGEIMYGGHITDDWDR+LCR YL E++
Sbjct: 4049 NNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTE 4108
Query: 4176 LTEDELMLAPGFAAPPYLDYAGYHQYIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRT 4235
+ E +++LAPGF PP LDY GYH+YI+E LPPESP LYGLHPNAEI FLTVTS LFRT
Sbjct: 4109 MLEGDVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRT 4168
Query: 4236 LLEMQPRNALSGDELGQSTEEK-----------------------------VKNVLDDIL 4266
+LEMQP+ SG G S EEK VK VLDDIL
Sbjct: 4169 VLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDIL 4228
Query: 4267 EKLPEEFNMAEIMQKNSNRSPYVLVCFQECERMNILIREIRISLEQLDLSLKGELALSPA 4326
EK+PE FNMAEIM K + ++PYV+V FQECERMNIL E+R SL++L+L LKGEL ++
Sbjct: 4229 EKIPETFNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTD 4288
Query: 4327 VEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRELDTWTQDLTLPAVVWLSGF 4386
VE AL YDTVPDTW AYPS GLA W+ DLLLR REL+ WT D LP VWL+GF
Sbjct: 4289 VEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGF 4348
Query: 4387 FNPQSFLTAIMQTMARKNEWPLDKTRLTADVTKKTKEDYGHPPREGAYLHGLFMEGARWD 4446
FNPQSFLTAIMQ+MARKNEWPLDK L+ +VTKK +ED PPREG+Y++GLFMEGARWD
Sbjct: 4349 FNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWD 4408
Query: 4447 TQAGTIVEARLKELACPMPVIFAKATPVDRQETKQTYECPVYRTKLRGPSYIWTFRLKSE 4506
TQ G I EARLKEL MPVIF KA PVDR ETK YECPVY+T++RGP+Y+WTF LK++
Sbjct: 4409 TQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTK 4468
Query: 4507 EKTAKWVLAGVALLLE 4522
EK AKW+LA VALLL+
Sbjct: 4469 EKAAKWILAAVALLLQ 4484
>gi|239745966 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
sapiens]
Length = 4485
Score = 5291 bits (13724), Expect = 0.0
Identities = 2618/4516 (57%), Positives = 3366/4516 (74%), Gaps = 78/4516 (1%)
Query: 52 SFAQDARVRFLGGRLAMMLGFTEEKWSQYLESEDNRQVLGEFLESTSPACLVFSFAASGR 111
+ A D R+ +L +++L F +KWS+ + +E+N + EF E LV + A+G
Sbjct: 2 TMAPDVRLEYLEEVASIVLKFKPDKWSKLIGAEENVALFTEFFEKPDVQVLVLTLNAAGM 61
Query: 112 LAASQEIPRDANHKLVFISKKITESIGVNDFSQVVLFGELPALSLGHVSAFLDEILVPVL 171
+ P+ K V+ K +E+I +++ +L+G++ + + A ++E+L +L
Sbjct: 62 IIPCLGFPQSLKSKGVYFIKTKSENINKDNYRARLLYGDISPTPVDQLIAVVEEVLSSLL 121
Query: 172 SNKNNHKSWSCFTSQDMEYHIEVMKKKMYIFRGKMSRRTLLPIPTVAGKMDLDQNCSENK 231
+ N W S+D+ + +K +M++ GK+ +TLLPIP G +D E
Sbjct: 122 NQSENMAGWPQVVSEDIVKQVHRLKNEMFVMSGKIKGKTLLPIPEHLGSLDGTLESMERI 181
Query: 232 PPSNERIILHAIESVVIEWSHQIQEIIERDSVQRLLNGLHLSPQAELDFWMMRRENLSCI 291
P S + ++LHAIE+ +I+WSHQI++++ +DS Q LL+GLH PQ E +FW R NL CI
Sbjct: 182 PSSLDNLLLHAIETTIIDWSHQIRDVLSKDSAQALLDGLHPLPQVEFEFWDTRLLNLKCI 241
Query: 292 YDQLQAPVVLKMVKILTTKQSSYFPTLKDIFLAVENALLEAQDVELYLRPLRRHIQCLQE 351
++QL P V K+V+IL +S Y+P L++++ V L EA D+ LYL+PLR ++ +++
Sbjct: 242 HEQLNRPKVNKIVEILEKAKSCYWPALQNVYTNVTEGLKEANDIVLYLKPLRILLEEMEQ 301
Query: 352 TEFPQTRILIAPLFHTICLIWSHSKFYNTPARVIVLLQEFCNLFINQATAYLSPEDLLRG 411
+F IA + TIC IW+ S++YNTPAR+IV+LQEFCN I +LSPE++L+G
Sbjct: 302 ADFTMLPTFIAKVLDTICFIWATSEYYNTPARIIVILQEFCNQIIEMTRTFLSPEEVLKG 361
Query: 412 ---EIEESLEKVQVAVNILKTFKNSFFNYRKKLASYFMGRKLRPWDFQSHLVFCRFDKFL 468
EIEE L + +AVN+LK ++ + +F ++ PW+F S L F R + F
Sbjct: 362 LQGEIEEVLSGISLAVNVLKELYQTYDFCCVNMKLFFKDKEPVPWEFPSSLAFSRINSFF 421
Query: 469 DRLIKIEDIFATTLEFEKLERLEFGGTKGAILNGQVHEMSEELMELCKLFKQSTYDPSDC 528
R+ IE+++ T +EF KLE++E GG +G +L V + +E+ EL K+F YDP D
Sbjct: 422 QRIQTIEELYKTAIEFLKLEKIELGGVRGNLLGSLVTRIYDEVFELVKVFADCKYDPLDP 481
Query: 529 TNMEFESDYVAFKSKTLEFDRRLGTIICEAFFNCNGLEAAFKLLTIFGNFLEKPVVMEIF 588
+ F+ DY F+ K + DRRL TI C+ F +C+ ++++ KLL + G +E+P+++
Sbjct: 482 GDSNFDRDYADFEIKIQDLDRRLATIFCQGFDDCSCIKSSAKLLYMCGGLMERPLILAEV 541
Query: 589 SLHYSTLVHMFNTELDVCKQLYNEHMKQIECGHV-VLNKNMPFTSGNMKWAQQVLQRLQM 647
+ YS ++ +F+ ELD K LY+ M E G++ +++KNMP +G +KW+ ++ +RL++
Sbjct: 542 APRYSVMLELFDAELDNAKILYDAQMAASEEGNIPLIHKNMPPVAGQLKWSLELQERLEV 601
Query: 648 FWSNFASLRYLFLGNPDHALVYQKYVEMTTLLDQFESRIYNEWKSNVDEICEFNLNQPLV 707
+ + + + + L YQKY EM LL +IY +W + VD+ C FNL QPL+
Sbjct: 602 SMKHLKHVEHPVMSGAEAKLTYQKYDEMMELLRCHREKIYQQWVAGVDQDCHFNLGQPLI 661
Query: 708 KFSAINGLLCVNFDPKLVAVLREVKYLLMLKKQDIPDSALAIFKKRNTILKYIGNLDLLV 767
A + L+ VNF LVAVLREVKYL ++++IPDSA ++F + T K++GNL+L+V
Sbjct: 662 LRDAASNLIHVNFSKALVAVLREVKYLNFQQQKEIPDSAESLFSENETFRKFVGNLELIV 721
Query: 768 QGYNKLKQTLLEVEYPLIEDELRAIDEQLTAATTWLTWQDD-CWGYIERVRAATSELEHR 826
YN++K + VE+ LI+ EL AID +L +A T L W + + YI+ VR L++R
Sbjct: 722 GWYNEIKTIVKAVEFLLIKSELEAIDVKLLSAETTLFWNGEGVFQYIQEVREILHNLQNR 781
Query: 827 VERTQKNVKVIQQTMRGWARCVLPPRREHRREAAFTLEDKGDLFTKKYKLIQGDGCKIHN 886
+++ ++N++ I Q M+ W+ L R+++++EA L+ + K+Y ++ G KI
Sbjct: 782 MQKAKQNIEGISQAMKDWSANPLFERKDNKKEALLDLDGRIANLNKRYAAVRDAGVKIQA 841
Query: 887 LVEENRKLFKANPSLDTWKIYVEFIDDIVVEGFFQAIMHDLDFFLKNTEKQLKPAPFFQA 946
+V EN +LF+A+ WK YV +IDD+V++ F Q I L F + N AP F+
Sbjct: 842 MVAENAELFRADTLSLPWKDYVIYIDDMVLDEFDQFIRKSLSFLMDNMVIDESIAPLFEI 901
Query: 947 QMILLPPEIVFKPSLDREAGDGFYDLVEEMLCNSFRMSAQMNRIATHLEIKNYQNDMDNM 1006
+M L + F P+L+ + GF L+E ++ + + ++ + R+A + NY+ D+++
Sbjct: 902 RMELDEDGLTFNPTLEVGSDRGFLALIEGLVNDIYNVARLIPRLAK--DRMNYKMDLEDN 959
Query: 1007 LGLAEVRQEIMNRVVNVINKVLDFRNTLETHTYLWVDDRAEFMKHFLLYGHAVSSDEMDA 1066
L E+R+E+ + V+N + + +++++ E ++YLW D+ EFMK+FL+YG AV+++++D
Sbjct: 960 TDLIEMREEVSSLVINAMKEAEEYQDSFERYSYLWTDNLQEFMKNFLIYGCAVTAEDLDT 1019
Query: 1067 HANEEIPEQPPTLEQFKEQIDIYEALYVQMSKFEDFRVFDSWFKVDMKPFKVSLLTIIKK 1126
++ IP+ PPTL QF+EQID YE LY ++SK E+ +VF W + D +PFK +LL+ I++
Sbjct: 1020 WTDDTIPKTPPTLAQFQEQIDSYEKLYEEVSKCENTKVFHGWLQCDCRPFKQALLSTIRR 1079
Query: 1127 WSWMFQEHLLRFVIDSLNELQEFIKETDSGLQRELNEGDHDGLVDIMVHLLAVRSRQRAT 1186
W +MF+ HL V +SL +L+ F+K GL + L EGD+DGLV++M HL+ V+ RQ AT
Sbjct: 1080 WGFMFKRHLSNHVTNSLADLEAFMKVARMGLTKPLKEGDYDGLVEVMGHLMKVKERQAAT 1139
Query: 1187 DELFEPLKETITLLESYGQKMPEQVYIQLEELPERWETTKKIAATVRHEVSPLHNAEVTL 1246
D +FEPLK+TI LL++YG++MPE+++++L+ELPE W TKK+A V+ V+PL EV++
Sbjct: 1140 DNMFEPLKQTIELLKTYGEEMPEEIHLKLQELPEHWANTKKLAIQVKLTVAPLQANEVSI 1199
Query: 1247 IRKKCILFDAKQAEFRERFRHYAPLGFNAENPYTALDKANEELEALEEEMLQMQESTRLF 1306
+R+KC F+ KQ EFRERFR AP F+ NPY +L+K + L+ M + +S LF
Sbjct: 1200 LRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNK----VFLLKGIMEALSKSGGLF 1255
Query: 1307 EVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTKTQWRQIHVEQMDVELRRFAKA 1366
EV +P+YKQ+K C +E++LLK LWD+++ V SI++W T+W+ I+VEQMD++ ++FAK
Sbjct: 1256 EVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQMDIDCKKFAK- 1314
Query: 1367 SSITEIWSLNKEVRVWDAYTGLEGTVKDMTASLRAITELQSPALRDRHWHQLMKAIGVKF 1426
++ SL+KE++ WDA+ GL+ TVK++ SLRA++ELQ+PA+R+RHW QLM+A VKF
Sbjct: 1315 ----DMRSLDKEMKTWDAFVGLDNTVKNVITSLRAVSELQNPAIRERHWQQLMQATQVKF 1370
Query: 1427 LINEATTLADLLALRLHRVEDDVRRIVDKAVKELGTEKVITEISQTWATMKFSYEVHYRT 1486
++E TTLADLL L LH ED+VR IVDKAVKE G EKV+ + TW+ M+F +E H RT
Sbjct: 1371 KMSEETTLADLLQLNLHSYEDEVRNIVDKAVKESGMEKVLKALDSTWSMMEFQHEPHPRT 1430
Query: 1487 GIPLLKSDEQLFETLEHNQVQLQTLLQSKYVEYFIEQVLSWQNKLNIADLVIFTWMEVQR 1546
G +LKS E L ETLE NQVQLQ L+ SKY+ +F+++V SWQ KL+ AD VI W EVQR
Sbjct: 1431 GTMMLKSSEVLVETLEDNQVQLQNLMMSKYLAHFLKEVTSWQQKLSTADSVISIWFEVQR 1490
Query: 1547 TWSHLESIFVCSEDIRIQLVKDARRFDGVDAEFKELMFKTAKVENVLEATCRPNLYEKLK 1606
TWSHLESIF+ SEDIR QL D++RFD ++ EFK LM K NV+EAT +P LY KL+
Sbjct: 1491 TWSHLESIFIGSEDIRTQLPGDSQRFDDINQEFKALMEDAVKTPNVVEATSKPGLYNKLE 1550
Query: 1607 DLQSRLSLCEKALAEYLETKRIAFPRFYFVSSADLLDILSKGAQPKQVTCHLAKLFDSIA 1666
L+ L++CEKALAEYLETKR+AFPRFYFVSSADLLDILS G P +V+ HL+KLFDS+
Sbjct: 1551 ALKKSLAICEKALAEYLETKRLAFPRFYFVSSADLLDILSNGNDPVEVSRHLSKLFDSLC 1610
Query: 1667 DLQFE-DNQDVSAHRAVGMYSKEKEYVPFQAECECVGHVETWLLQLEQTMQETVRHSITE 1725
L+F D D +GMYSKE EY+ F EC+ G VE WL ++ M T+RH I E
Sbjct: 1611 KLKFRLDASDKPLKVGLGMYSKEDEYMVFDQECDLSGQVEVWLNRVLDRMCSTLRHEIPE 1670
Query: 1726 AIVAYEEKPRELWIFDFPAQVALTSSQIWWTTDVGIAFSRLEEGYETALKDFHKKQISQL 1785
A+V YEEKPRE WI D+PAQ IWWTT+VG+AF+RLEEGYE A++D++KKQISQL
Sbjct: 1671 AVVTYEEKPREQWILDYPAQ-------IWWTTEVGLAFARLEEGYENAIRDYNKKQISQL 1723
Query: 1786 NTLITLLLGELPPGDRQKIMTICTIDVHARDVVAKLISQKQVVVSPQAFTWLSQLRHRWE 1845
N LITLL+G L GDR KIMTICTIDVHARDVVAK+I V S QAFTW +QLRHRW+
Sbjct: 1724 NVLITLLMGNLNAGDRMKIMTICTIDVHARDVVAKMI-----VESSQAFTWQAQLRHRWD 1778
Query: 1846 DTQKHCFVNICDAQFQYFYEYLGNSPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTG 1905
+ ++HCF NICDAQ QY YEYLGN+PRLVITPLTDRCYITLTQSLHL M GAPAGPAGTG
Sbjct: 1779 EEKRHCFANICDAQIQYSYEYLGNTPRLVITPLTDRCYITLTQSLHLIMGGAPAGPAGTG 1838
Query: 1906 KTETTKDLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGAWGCFDEFNRISVEVLSVV 1965
KTETTKDLGRALG MVYVFNCSEQMDYKS GNIYKGL QTGAWGCFDEFNRISVEVLSV+
Sbjct: 1839 KTETTKDLGRALGTMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRISVEVLSVI 1898
Query: 1966 AVQVKMIHDAIRNRKKRFVFLGEAITLKPSVGIFITMNPGYAGRTELPENLKALFRPCAM 2025
AVQVK + DAIR +KK F FLGE I L P+VGIFITMNPGYAGR ELPENLKALFRPCAM
Sbjct: 1899 AVQVKCVQDAIRAKKKAFNFLGEIIGLIPTVGIFITMNPGYAGRAELPENLKALFRPCAM 1958
Query: 2026 VAPDIELICEILLVAEGFVDARALARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAG 2085
V PD ELICEI+L+AEGF++AR LARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAG
Sbjct: 1959 VVPDFELICEIMLMAEGFLEARLLARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAG 2018
Query: 2086 SLKRGDKNRPEDQVLMRALRDFNMPKIVTDDIPVFLGLVGDLFPALDVPRRRKLHFEQMV 2145
SLKRGD +R EDQVLMRALRDFN+PKIVTDD+PVF+GL+GDLFPALDVPR+R L+FE+++
Sbjct: 2019 SLKRGDPSRAEDQVLMRALRDFNIPKIVTDDLPVFMGLIGDLFPALDVPRKRDLNFEKII 2078
Query: 2146 RQSTLELRLQPEESFILKVVQLEELLAVRHSVFVVGNAGTGKSKILRTLNRTYVNMKQKP 2205
+QS +EL+LQ E+SF+LKVVQLEELL VRHSVF+VGNAG+GKS++L++LN+TY N+K+KP
Sbjct: 2079 KQSIVELKLQAEDSFVLKVVQLEELLQVRHSVFIVGNAGSGKSQVLKSLNKTYQNLKRKP 2138
Query: 2206 VWNDLNPKAVTTDELFGFIHHATREWKDGKIVYSYFIGLFSSILREQANLKHDGPKWIVL 2265
V DL+PKAVT DELFG I+ TREWKDG LFS+I+R+ AN+ HDGPKWI+L
Sbjct: 2139 VAVDLDPKAVTCDELFGIINPVTREWKDG---------LFSTIMRDLANITHDGPKWIIL 2189
Query: 2266 DGDIDPMWIESLNTVMDDNKVLTLASNERIALTPFMRLLFEIHHLRSATPATVSRAGILY 2325
DGDIDPMWIESLNTVMDDNKVLTLASNERI L MRL+FEI HLR+ATPATVSRAGILY
Sbjct: 2190 DGDIDPMWIESLNTVMDDNKVLTLASNERIPLNRTMRLVFEISHLRTATPATVSRAGILY 2249
Query: 2326 VNPQDLGWNPYVASWIDRRRHQSEKANLTILFDKYVPACLDKLRTSFKTITSIPESSLVQ 2385
+NP DLGWNP V+SWI+RR+ QSEKANL ILFDKY+P CLDKLR FK IT +PE +++Q
Sbjct: 2250 INPADLGWNPVVSSWIERRKVQSEKANLMILFDKYLPTCLDKLRFGFKKITPVPEITVIQ 2309
Query: 2386 TLCVLLECLLTPENVPSDSPKEVYEVYFVFACIWAFGGTLLQDQISDYQADFSRWWQKEM 2445
T+ LLECLLT + VP DSP+E+YE+YFVF C WAFGG + QDQ+ DY+ +FS+WW E
Sbjct: 2310 TILYLLECLLTEKTVPPDSPRELYELYFVFTCFWAFGGAMFQDQLVDYRVEFSKWWINEF 2369
Query: 2446 KAVKFPSQGTIFDYYVDHKTKKLLPWADKIAQFTMDPDVPLQTVLVHTTETARLRYFMEL 2505
K +KFPSQGTIFDYY+D TKK LPW DK+ F +DPDVPLQ LVHTTET R+RYFM+L
Sbjct: 2370 KTIKFPSQGTIFDYYIDPDTKKFLPWTDKVPSFELDPDVPLQASLVHTTETIRIRYFMDL 2429
Query: 2506 LLEKGKPLMLVGNAGVGKTVFVGDTLASLSED-YIVSRVPFNYYTTSTALQKILEKPLEK 2564
L+EK P+MLVGNAG GK+V +GD L SL+ D Y+V VPFN+YTTS LQ +LEKPLEK
Sbjct: 2430 LMEKSWPVMLVGNAGTGKSVLMGDKLESLNTDNYLVQAVPFNFYTTSAMLQGVLEKPLEK 2489
Query: 2565 KAGHNYGPGGNKKLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYDRQKVMLKEIHN 2624
K+G NYGP G KKL+YFIDDMNMPEVD YGTV PHTLIRQH+D+ HWYDR K+ LK+IHN
Sbjct: 2490 KSGRNYGPPGTKKLVYFIDDMNMPEVDKYGTVAPHTLIRQHMDHRHWYDRHKLTLKDIHN 2549
Query: 2625 CQYVACMNPMVGSFTINPRLQRHFTVFAFNFPSLDALNTIYGQIFSFHFQQQAFAPSILR 2684
CQYVACMNP GSFTI+ RLQRHF VFA +FP +AL TIY I + H ++ + +I R
Sbjct: 2550 CQYVACMNPTSGSFTIDSRLQRHFCVFAVSFPGQEALTTIYNTILTQHLAFRSVSMAIQR 2609
Query: 2685 SGPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFASPECLKGPLDLIHL 2744
L+ A +A HQ + FLPTAIKFHY+FNLRDLSN+FQG+LF++ E LK PLDL+ L
Sbjct: 2610 ISSQLVAAALALHQKITATFLPTAIKFHYVFNLRDLSNIFQGLLFSTAEVLKTPLDLVRL 2669
Query: 2745 WLHESARVYGDKLIDKKDCDLFQRRMLETAYKYFEGIDSHMLLQQPLIYCHFADRGKDPH 2804
WLHE+ RVYGDK++D+KD + R + + K+F+ + +L +P I+CHFA DP
Sbjct: 2670 WLHETERVYGDKMVDEKDQETLHRVTMASTKKFFDDLGDELLFAKPNIFCHFAQGIGDPK 2729
Query: 2805 YMPVKDWEVLKTILTETLDNYNELNAAMHLVLFEDAMQHVCRISRILRTPQGCALLVGVG 2864
Y+PV D L +L + LD+YNE+NA M+LVLFEDA+ H+CRI+RIL +P+G ALLVGVG
Sbjct: 2730 YVPVTDMAPLNKLLVDVLDSYNEVNAVMNLVLFEDAVAHICRINRILESPRGNALLVGVG 2789
Query: 2865 GSGKQSLSRLAAYLRGLEVFQITLTEGYGIQELRVDLANLYIRTGAKNMPTVFLLTDAQV 2924
GSGKQSLSRLAAY+ GL+VFQITL +GYGI +L++DLA YI+ KN+P+VFL+TD+QV
Sbjct: 2790 GSGKQSLSRLAAYISGLDVFQITLKKGYGIPDLKIDLAAQYIKAAVKNVPSVFLMTDSQV 2849
Query: 2925 LDESFLVLINDLLASGEIPDLFSDEDVDKIISGIHNEVHALGMVDSRENCWKFFMARVRL 2984
+E FLVLINDLLASGEIP LF +++V+ IIS + +V +LGM D+RE CWKFF+ +VR
Sbjct: 2850 AEEQFLVLINDLLASGEIPGLFMEDEVENIISSMRPQVKSLGMNDTRETCWKFFIEKVRR 2909
Query: 2985 QLKIILCFSPVGRTLRVRARKFPAIVNCTAIDWFHAWPQEALVSVSRRFIEETKGIEPVH 3044
QLK+ILCFSPVG LRVRARKFPA+VNCTAIDWFH WP++ALVSVS RF+EET+GI
Sbjct: 2910 QLKVILCFSPVGSVLRVRARKFPAVVNCTAIDWFHEWPEDALVSVSARFLEETEGIPWEV 2969
Query: 3045 KDSISLFMAHVHTTVNEMSTRYYQNERRHNYTTPKSFLEQISLFKNLLKKKQNEVSEKKE 3104
K SIS FM++VHTTVNEMS Y ERR+NYTTPK+FLEQI L++NLL KK+ E+ K E
Sbjct: 2970 KASISFFMSYVHTTVNEMSRVYLATERRYNYTTPKTFLEQIKLYQNLLAKKRTELVAKIE 3029
Query: 3105 RLVNGIQKLKTTASQVGDLKARLASQEAELQLRNHDAEALITKIGLQTEKVSREKTIADA 3164
RL NG+ KL++TASQV DLKA+LA QEAEL+ +N A+ LI +G++ EKVS+EK IAD
Sbjct: 3030 RLENGLMKLQSTASQVDDLKAKLAIQEAELKQKNESADQLIQVVGIEAEKVSKEKAIADQ 3089
Query: 3165 EERKVTAIQTEVFQKQRECEADLLKAEPALVAATAALNTLNRVNLSELKAFPNPPIAVTN 3224
EE KV I V +KQ+ CE DL KAEPAL+AA AL+TLN+ NL+ELK+F +PP AV N
Sbjct: 3090 EEVKVEVINKNVTEKQKACETDLAKAEPALLAAQEALDTLNKNNLTELKSFGSPPDAVVN 3149
Query: 3225 VTAAVMVLLAPRGRVPKDRSWKAAKVFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLK 3284
VTAAVM+L AP G++PKD+SWKAAK+ MGKVD FL +L +DKEHIPE CLK Y
Sbjct: 3150 VTAAVMILTAPGGKIPKDKSWKAAKIMMGKVDTFLDSLKKFDKEHIPEACLKAFKP-YQG 3208
Query: 3285 DPEFNPNLIRTKSFAAAGLCAWVINIIKFYEVYCDVEPKRQALAQANLELAAATEKLEAI 3344
+P F+P IR+KS AAAGLC+W INI++FYEVYCDV PKRQAL +AN ELA A EKL I
Sbjct: 3209 NPTFDPEFIRSKSTAAAGLCSWCINIVRFYEVYCDVAPKRQALEEANAELAEAQEKLSRI 3268
Query: 3345 RKKLVDLDRNLSRLTASFEKATAEKVRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSI 3404
+ K+ +L+ NLS LT++FEKATAEK++CQ+E + TN+ I LANRLV L ++ IRW +S+
Sbjct: 3269 KNKIAELNANLSNLTSAFEKATAEKIKCQQEADATNRVILLANRLVGGLASENIRWAESV 3328
Query: 3405 KSFEAQEKTLCGDVLLTAAFVSYVGPFTRQYRQELVHCKWVPFLQQ-KVSIPLTEGLDLI 3463
++F +Q TLCGDVLL +AFVSYVG FT++YR EL+ W+P++ KV IP+T GLD +
Sbjct: 3329 ENFRSQGVTLCGDVLLISAFVSYVGYFTKKYRNELMEKFWIPYIHNLKVPIPITNGLDPL 3388
Query: 3464 SMLTDDATIAAWNNEGLPSDRMSTENAAILTHCERWPLVIDPQQQGIKWIKNKYGMDLKV 3523
S+LTDDA +A WNN+GLPSDRMSTENA IL + ERWPL++D Q QGIKWIKNKY +LK
Sbjct: 3389 SLLTDDADVATWNNQGLPSDRMSTENATILGNTERWPLIVDAQLQGIKWIKNKYRSELKA 3448
Query: 3524 THLGQKGFLNAIETALAFGDVILIENLEETIDPVLDPLLGRNTIKKGKYIRIGDKECEFN 3583
LGQK +L+ IE A++ GD +LIEN+ ET+DPVLDPLLGRNTIKKGKYI+IGDKE E++
Sbjct: 3449 IRLGQKSYLDVIEQAISEGDTLLIENIGETVDPVLDPLLGRNTIKKGKYIKIGDKEVEYH 3508
Query: 3584 KNFRLILHTKLANPHYKPELQAQTTLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLT 3643
FRLILHTK NPHYKPE+QAQ TL+NF VT DGLE QLLA VV+ ERPDLE+LK LT
Sbjct: 3509 PKFRLILHTKYFNPHYKPEMQAQCTLINFLVTRDGLEDQLLAAVVAKERPDLEQLKANLT 3568
Query: 3644 KHQNDFKIELKYLEDDLLLRLSAAEGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENER 3703
K QN+FKI LK LED LL RLSAA G+FL DT LVE LE TK T +EIE KV+EAK E
Sbjct: 3569 KSQNEFKIVLKELEDSLLARLSAASGNFLGDTALVENLETTKHTASEIEEKVVEAKITEV 3628
Query: 3704 KINEARECYRPVAARASLLYFVINDLQKINPLYQFSLKAFNVLFHRAIEQADKVEDMQGR 3763
KINEARE YRP A RASLLYF++NDL KINP+YQFSLKAFNV+F +AI++ +++ R
Sbjct: 3629 KINEARENYRPAAERASLLYFILNDLNKINPVYQFSLKAFNVVFEKAIQRTTPANEVKQR 3688
Query: 3764 ISILMESITHAVFLYTSQALFEKDKLTFLSQMAFQILLRKKEIDPLELDFLLRFTVEHTH 3823
+ L + IT++V++YT++ LFE+DKL FL+Q+ FQ+L KKE++P+ELDFLLRF +
Sbjct: 3689 VINLTDEITYSVYMYTARGLFERDKLIFLAQVTFQVLSMKKELNPVELDFLLRFPFKAGV 3748
Query: 3824 LSPVDFLTSQSWSAIKAIAVMEEFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKKS 3883
+SPVDFL Q W IKA++ M+EF+ +D D+EGSAK+W+K VESE PEKE P+EWK K+
Sbjct: 3749 VSPVDFLQHQGWGGIKALSEMDEFKNLDSDIEGSAKRWKKLVESEAPEKEIFPKEWKNKT 3808
Query: 3884 LIQKLILLRAMRPDRMTYALRNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPG 3943
+QKL ++R +RPDRMTYA++NFVEEK+G+K+VE ++ K++EESSP+T IFFILSPG
Sbjct: 3809 ALQKLCMVRCLRPDRMTYAIKNFVEEKMGSKFVEGRSVEFSKSYEESSPSTSIFFILSPG 3868
Query: 3944 VDALKDLEILGKRLGFTIDSGKFHNVSLGQGQETVAEVALEKASKGGHWVILQ------- 3996
VD LKD+E LGK+LGFTID+GK HNVSLGQGQE VAE AL+ A++ GHWVILQ
Sbjct: 3869 VDPLKDVEALGKKLGFTIDNGKLHNVSLGQGQEVVAENALDVAAEKGHWVILQVRGGQHC 3928
Query: 3997 -NVHLVAKWLGTLEKLLERFSQGSHRDYRVFMSAESAPTPDEHIIPQGLLENSIKITNEP 4055
N+HLVA+WLGTL+K LE +S GSH DYRVF+SAE AP+P+ HIIPQG+LEN+IKITNEP
Sbjct: 3929 RNIHLVARWLGTLDKKLEHYSTGSHEDYRVFISAEPAPSPETHIIPQGILENAIKITNEP 3988
Query: 4056 PTGMLANLHAALYNFDQDTLEICSKEQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPF 4115
PTGM ANLH AL F QDTLE+C+KE EFK +LF+LCYFHA VA R +FG QGW+RSYPF
Sbjct: 3989 PTGMHANLHKALDLFTQDTLEMCTKEMEFKCMLFALCYFHAVVAERRKFGAQGWNRSYPF 4048
Query: 4116 NPGDLTICASVLYNYLEANSKVPWEDLRYLFGEIMYGGHITDDWDRKLCRVYLEEFMNPS 4175
N GDLTI +VLYNYLEAN KVPW+DLRYLFGEIMYGGHITDDWDR+LCR YL E++
Sbjct: 4049 NNGDLTISINVLYNYLEANPKVPWDDLRYLFGEIMYGGHITDDWDRRLCRTYLAEYIRTE 4108
Query: 4176 LTEDELMLAPGFAAPPYLDYAGYHQYIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRT 4235
+ E +++LAPGF PP LDY GYH+YI+E LPPESP LYGLHPNAEI FLTVTS LFRT
Sbjct: 4109 MLEGDVLLAPGFQIPPNLDYKGYHEYIDENLPPESPYLYGLHPNAEIGFLTVTSEKLFRT 4168
Query: 4236 LLEMQPRNALSGDELGQSTEEK-----------------------------VKNVLDDIL 4266
+LEMQP+ SG G S EEK VK VLDDIL
Sbjct: 4169 VLEMQPKETDSGAGTGVSREEKAGSLKLLPSERKGEDLELRRGGCPGTGFQVKAVLDDIL 4228
Query: 4267 EKLPEEFNMAEIMQKNSNRSPYVLVCFQECERMNILIREIRISLEQLDLSLKGELALSPA 4326
EK+PE FNMAEIM K + ++PYV+V FQECERMNIL E+R SL++L+L LKGEL ++
Sbjct: 4229 EKIPETFNMAEIMAKAAEKTPYVVVAFQECERMNILTNEMRRSLKELNLGLKGELTITTD 4288
Query: 4327 VEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRELDTWTQDLTLPAVVWLSGF 4386
VE AL YDTVPDTW AYPS GLA W+ DLLLR REL+ WT D LP VWL+GF
Sbjct: 4289 VEDLSTALFYDTVPDTWVARAYPSMMGLAAWYADLLLRIRELEAWTTDFALPTTVWLAGF 4348
Query: 4387 FNPQSFLTAIMQTMARKNEWPLDKTRLTADVTKKTKEDYGHPPREGAYLHGLFMEGARWD 4446
FNPQSFLTAIMQ+MARKNEWPLDK L+ +VTKK +ED PPREG+Y++GLFMEGARWD
Sbjct: 4349 FNPQSFLTAIMQSMARKNEWPLDKMCLSVEVTKKNREDMTAPPREGSYVYGLFMEGARWD 4408
Query: 4447 TQAGTIVEARLKELACPMPVIFAKATPVDRQETKQTYECPVYRTKLRGPSYIWTFRLKSE 4506
TQ G I EARLKEL MPVIF KA PVDR ETK YECPVY+T++RGP+Y+WTF LK++
Sbjct: 4409 TQTGVIAEARLKELTPAMPVIFIKAIPVDRMETKNIYECPVYKTRIRGPTYVWTFNLKTK 4468
Query: 4507 EKTAKWVLAGVALLLE 4522
EK AKW+LA VALLL+
Sbjct: 4469 EKAAKWILAAVALLLQ 4484
>gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]
Length = 4471
Score = 2159 bits (5595), Expect = 0.0
Identities = 1404/4476 (31%), Positives = 2330/4476 (52%), Gaps = 257/4476 (5%)
Query: 151 LPALSLG-HVSAFLDEILVPVLSNKNNHKS-WSCFTSQDMEYH-IEVMKKKMYIFRGKMS 207
LPALS H ++ + +SN + H+S + +EYH I++++ + + K +
Sbjct: 149 LPALSFNQHRTSTTVGVTSGEVSNSSEHESDLPPMPGEAVEYHSIQLIRDEFLMNVQKFA 208
Query: 208 RRTLLPIPTVAGKMDLDQNC----SENKPPSNERIILHAIESVVIEWSHQIQEIIERDSV 263
+ + G++ L+ E + + + +E VI W +QI +E +
Sbjct: 209 SNIQRTMQQLEGEIKLEMPIISVEGEVSDLAADPETVDILEQCVINWLNQISTAVEAQ-L 267
Query: 264 QRLLNGLHLSPQAELDFWMMRRENLSCIYDQLQAPVVLKMVKILTTKQSSYFPTLKDIFL 323
++ G P AE++FW R LS +++Q + P+V K++ ++ S L+ +F
Sbjct: 268 KKTPQGK--GPLAEIEFWRERNATLSALHEQTKLPIVRKVLDVIKESDSMLVANLQPVFT 325
Query: 324 AVENALLEAQDVELYLRPLRRHIQCLQE-TEFPQTRILIAPLFHTICLIWSHSKFYNTPA 382
+ EA D +L + R+ + + + F I + + ++W S+ YN
Sbjct: 326 ELFKFHTEASDNVRFLSTVERYFKNITHGSGFHVVLDTIPAMMSALRMVWIISRHYNKDE 385
Query: 383 RVIVLLQEFCNLFINQATAYLSPEDLLRGEIEESLEKVQVAVNILKTFKNSFFNYRKKLA 442
R+I L++ + ++ L + + K A N L+ +K ++F+ R K+
Sbjct: 386 RMIPLMERIAWEIAERVCRVVNLRTLFKENRASAQSKTLEARNTLRLWKKAYFDTRAKIE 445
Query: 443 SYFMGRKLRPWDFQSHLVFCRFDKFLDRLIKIEDIFATTLEFEKLERLEFGGTKGAILNG 502
+ GR+ R W+F +F R D + D+ EF + FG A+
Sbjct: 446 A--SGREDR-WEFDRKRLFERTDYMATICQDLSDVLQILEEFYNI----FGPELKAV--- 495
Query: 503 QVHEMSEELMELCKLFKQSTYDPSDCTNMEFESDYVAFKSKTLEFDRRLGTIICEAFFNC 562
T DP +R+ ++C
Sbjct: 496 -------------------TGDP-----------------------KRIDDVLCRV---- 509
Query: 563 NGLEAAFKLLTIFGNFLEKPVVMEIFSLHYSTLVHMFNTE--LDVCKQLYNEHMKQIECG 620
+GL + LT F F K S + ++ F E +D+ +++ ++++
Sbjct: 510 DGLVTPMENLT-FDPFSIKS------SQFWKYVMDEFKIEVLIDIINKIFVQNLE----- 557
Query: 621 HVVLNKNMPFTSGNMKWAQQVLQRLQMFWSNFASLRYLFLGNPDHALVYQKYVEMTTLLD 680
+ L KN P +G + W + + R++ F ++ + L + V QKY+E+ +
Sbjct: 558 NPPLYKNHPPVAGAIYWERSLFFRIKHTILRFQEVQEI-LDSDRGQEVKQKYLEVGRTMK 616
Query: 681 QFESRIYNEWKSNVDEICEFNLNQPLVKFSAI----------NGLLCVNFDPKLVAVLRE 730
++E R Y +W +++ + + L+ S+I + +NF P L ++ E
Sbjct: 617 EYEDRKYEQWMEVTEQVLPALMKKSLLTKSSIATEEPSTLERGAVFAINFSPALREIINE 676
Query: 731 VKYLLMLKKQDIPDSALAIFKKRNTILKYIGNLDLLVQGYNKLKQTLLEVEYPLIEDELR 790
KYL L +P+ A + + + L+Y + ++ Y+ L TL + E L++D +
Sbjct: 677 TKYLEQLGFT-VPELARNVALQEDKFLRYTAGIQRMLDHYHMLIGTLNDAESVLLKDHSQ 735
Query: 791 AIDEQLTAATTWLTWQDDCWG-YIERVRAATSELEHRVERTQKNVKVIQQTMR------- 842
+ + L W G YI + A + E V + KN I +
Sbjct: 736 ELLRVFRSGYKRLNWNSLGIGDYITGCKQAIGKFESLVHQIHKNADDISSRLTLIEAINL 795
Query: 843 -----GWARCVLPPRREHRREAAFTLEDKGDLFTKKYKLIQGDGCKIHNLVEENRKLFKA 897
+ LP +E D + Y I K+ LV
Sbjct: 796 FKYPAAKSEEELPGVKEFFEHIERERASDVDHMVRWYLAIGPLLTKVEGLVVHTNT--GK 853
Query: 898 NPSLDTWKIYVEFIDDIVVEGFFQAIMHDLDFFLKNTEKQLKPAPFFQAQMILLPPEIVF 957
P L + Y ++ + + E + I+ +L F L P F + IL PEI+
Sbjct: 854 APKLAS---YYKYWEKKIYEVLTKLILKNLQSF---NSLILGNVPLFHTETILTAPEIIL 907
Query: 958 KPSLDREAGDGFYDLVEEMLCNSFRMSAQMNRIATH----------LEIKNYQNDMDNML 1007
P+ + E + V + + MN + I N+ ND+
Sbjct: 908 HPNTN-EIDKMCFHCVRNCVEITKHFVRWMNGSCIECPPQKGEEEEVVIINFYNDISLNP 966
Query: 1008 GLAEVRQEIMNRVVNVINKVLDFRNTLETHTYLWVDDRAEFMKHFLLYGHAVSSDEMDAH 1067
+ E I V ++ ++ + + + LW D+A M+ F
Sbjct: 967 QIIEQAVMIPQNVHRILINLMKYLQKWKRYRPLWKLDKAIVMEKFAA------------- 1013
Query: 1068 ANEEIPEQPPTLEQFKEQIDIYEALYVQMSKFEDFRVFDSWFKVDMKPFKVSLLTIIKKW 1127
++PP + + E++ Y + ++ + + + ++ ++ ++ K W
Sbjct: 1014 ------KKPPCVA-YDEKLQFYSKIAYEVMRHPLIKD-EHCIRLQLRHLANTVQENAKSW 1065
Query: 1128 SWMFQEHLLRFVIDSLNELQEFIKETDSGLQRELNEGDHDGLVDIMVHLLAVRSRQRATD 1187
+ L + L L E ++ L++ N + L ++ + +RS+ +
Sbjct: 1066 VISLGKLLNESAKEELYNLHEEMEHLAKNLRKIPNT--LEDLKFVLATIAEIRSKSLVME 1123
Query: 1188 ELFEPLKETITLLESYGQKMPEQVYIQLEELPERWETTKKIAATVRHEVSPLHNAEVTLI 1247
+ ++E + Y P+ ++++ W + V H + + L
Sbjct: 1124 LRYRDVQERYRTMAMYNLFPPDAEKELVDKIESIWSNLFNDSVNVEHALGDIKRTFTELT 1183
Query: 1248 RKKCILFDAKQAEFRERFRHYAP--LGFNAENPYTALDKANEELEALEEEMLQMQESTRL 1305
R + + + + EF +RF P +G + + L EL E+ ++ + +L
Sbjct: 1184 RGEIMNYRVQIEEFAKRFYSEGPGSVGDDLDKGVELLGVYERELARHEKSRQELANAEKL 1243
Query: 1306 FEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTKTQWRQIHVEQMDVELRRFAK 1365
F++ + Y ++ + +KE+ L+ ++++ ++ + + W++T W ++V+ + + F +
Sbjct: 1244 FDLPITMYPELLKVQKEMSGLRMIYELYEGLKVAKEEWSQTLWINLNVQILQEGIEGFLR 1303
Query: 1366 ASSITEIWSLNKEVRVWDAYTGLEGTVKDMTASLRAITELQSPALRDRHWHQLMKAIGVK 1425
A + L + VR LE +K S+ + +L++ ALRDRHW +LM+ V
Sbjct: 1304 A-----LRKLPRPVRGLSVTYYLEAKMKAFKDSIPLLLDLKNEALRDRHWKELMEKTSVF 1358
Query: 1426 FLINEATTLADLLALRLHRVEDDVRRIVDKAVKELGTEKVITEISQTWATMKFSYEVHYR 1485
F + E TL ++ A+ LH+ D + IV A+KE+ EK + EI TW MKF+ V Y
Sbjct: 1359 FEMTETFTLENMFAMELHKHTDVLNEIVTAAIKEVAIEKAVKEILDTWENMKFTV-VKYC 1417
Query: 1486 TGIP----LLKSDEQLFETLEHNQVQLQTLLQSKYVEYFIEQVLSWQNKLNIADLVIFTW 1541
G +L S +++ ++L+ N LQ++ S++V F++ V W+ L++ VI W
Sbjct: 1418 KGTQERGYILGSVDEIIQSLDDNTFNLQSISGSRFVGPFLQTVHKWEKTLSLIGEVIEIW 1477
Query: 1542 MEVQRTWSHLESIFVCSEDIRIQLVKDARRFDGVDAEFKELMFKTAKVENVLEATCR-PN 1600
M VQR W +LESIF+ DIR QL ++A++FD +D FK +M +T K + V++ C PN
Sbjct: 1478 MLVQRKWMYLESIFI-GGDIRSQLPEEAKKFDNIDKVFKRIMGETLK-DPVIKRCCEAPN 1535
Query: 1601 LYEKLKDLQSRLSLCEKALAEYLETKRIAFPRFYFVSSADLLDILSKGAQPKQVTCHLAK 1660
L+++ L C+K+L +YL++KR AFPRF+F+S +LL IL + P V H+ K
Sbjct: 1536 RLSDLQNVSEGLEKCQKSLNDYLDSKRNAFPRFFFISDDELLSILGS-SDPLCVQEHMIK 1594
Query: 1661 LFDSIADLQFEDNQDVSAHRAVGMYSKEKEYVPFQAECECVGHVETWLLQLEQTMQETVR 1720
++D+IA L+F D D M S E E + F+ G VE W+ + M+ T R
Sbjct: 1595 MYDNIASLRFNDG-DSGEKLVSAMISAEGEVMEFRKILRAEGRVEDWMTAVLNEMRRTNR 1653
Query: 1721 HSITEAIVAY-EEKPRELWIFDFPAQVALTSSQIWWTTDVGIAFSRLEEGYETALKDFHK 1779
EAI Y E++ R W+ + V L +SQ+WWT +V F + ++G + A+K++ +
Sbjct: 1654 LITKEAIFRYCEDRSRVDWMLLYQGMVVLAASQVWWTWEVEDVFHKAQKGEKQAMKNYGR 1713
Query: 1780 KQISQLNTLITLLLGELPPGDRQKIMTICTIDVHARDVVAKLISQKQVVVSPQAFTWLSQ 1839
K Q++ L+T + L DR+K T+ IDVHARD+V I + ++ + F W SQ
Sbjct: 1714 KMHRQIDELVTRITMPLSKNDRKKYNTVLIIDVHARDIVDSFI--RGSILEAREFDWESQ 1771
Query: 1840 LRHRWEDTQKHCFVNICDAQFQYFYEYLGNSPRLVITPLTDRCYITLTQSLHLTMSGAPA 1899
LR W+ + C F Y YEY+G + RLVITPLTDR Y+TLTQ+L + + GAPA
Sbjct: 1772 LRFYWDREPDELNIRQCTGTFGYGYEYMGLNGRLVITPLTDRIYLTLTQALSMYLGGAPA 1831
Query: 1900 GPAGTGKTETTKDLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGAWGCFDEFNRISV 1959
GPAGTGKTETTKDL +ALG++ V NC E MDY+++G I+ GL Q GAWGCFDEFNRI
Sbjct: 1832 GPAGTGKTETTKDLAKALGLLCVVTNCGEGMDYRAVGKIFSGLAQCGAWGCFDEFNRIDA 1891
Query: 1960 EVLSVVAVQVKMIHDAIRNRKKRFVFLGEAITLKPSVGIFITMNPGYAGRTELPENLKAL 2019
VLSV++ Q++ I +A+ ++ F F G+ I+L +GIFITMNPGYAGRTELPE++KAL
Sbjct: 1892 SVLSVISSQIQTIRNALIHQLTTFQFEGQEISLDSRMGIFITMNPGYAGRTELPESVKAL 1951
Query: 2020 FRPCAMVAPDIELICEILLVAEGFVDARALARKFITLYTLCKELLSKQDHYDWGLRAIKS 2079
FRP ++ PD++ ICEI+L +EGF++A+ LA+K LY L +E LSKQ HYD+GLRA+KS
Sbjct: 1952 FRPVVVIVPDLQQICEIMLFSEGFLEAKTLAKKMTVLYKLAREQLSKQYHYDFGLRALKS 2011
Query: 2080 VLVVAGSLKRGDKNRPEDQVLMRALRDFNMPKIVTDDIPVFLGLVGDLFPALDVPRRRKL 2139
VLV+AG LKRG + ED VLMRALRD N+PK V +D+P+FLGL+ DLFP LD PR R
Sbjct: 2012 VLVMAGELKRGSSDLREDVVLMRALRDMNLPKFVFEDVPLFLGLISDLFPGLDCPRVRYP 2071
Query: 2140 HFEQMVRQSTLELRLQPEESFILKVVQLEELLAVRHSVFVVGNAGTGKSKILRTLNRTYV 2199
F V Q E + KVVQ+ E + RH+ VVG GKS ++ TL +
Sbjct: 2072 DFNDAVEQVLEENGYAVLPIQVDKVVQMFETMLTRHTTMVVGPTRGGKSVVINTLCQAQT 2131
Query: 2200 NMKQKPVWNDLNPKAVTTDELFGFIHHATREWKDGKIVYSYFIGLFSSILREQANLKHDG 2259
+ LNPKAV+ EL+G + TR+W D G+ S+I RE N D
Sbjct: 2132 KLGLTTKLYILNPKAVSVIELYGILDPTTRDWTD---------GVLSNIFRE-INKPTDK 2181
Query: 2260 P--KWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIALTPFMRLLFEIHHLRSATPAT 2317
K+I+ DGD+D +W+E++N+VMDDN++LTLA+ ERI L LLFE+ L+ A+PAT
Sbjct: 2182 KERKYILFDGDVDALWVENMNSVMDDNRLLTLANGERIRLQAHCALLFEVGDLQYASPAT 2241
Query: 2318 VSRAGILYVNPQDLGWNPYVASWIDRRRHQSEKANLTILFDKYVPACLDKL-------RT 2370
VSR G++YV+P++L + PY W+++ ++ E+ NL LF+KYVP +D + R
Sbjct: 2242 VSRCGMVYVDPKNLKYRPYWKKWVNQIPNKVEQYNLNSLFEKYVPYLMDVIVEGIVDGRQ 2301
Query: 2371 SFKTITSIPESSL--VQTLCVLLECLLTPENVPSDSPKEVYEVYFVFACIWAFGGTLLQD 2428
+ K T +P++ L V L +L+ LL E D + E YF+ A + G +LL+D
Sbjct: 2302 AEKLKTIVPQTDLNMVTQLAKMLDALLEGEIEDLD----LLECYFLEALYCSLGASLLED 2357
Query: 2429 ---QISDYQADFSRWWQKEMKAV-----KFPSQ-GTIFDYYVDHKTKKLLPWADKIAQFT 2479
+ +Y + + + V + P Q T++D++ D+K + +PW+ + ++
Sbjct: 2358 GRMKFDEYIKRLASLSTVDTEGVWANPGELPGQLPTLYDFHFDNKRNQWVPWSKLVPEYI 2417
Query: 2480 MDPDVPLQTVLVHTTETARLRYFMELLLEKGKPLMLVGNAGVGKTVFVGDTLASLSED-Y 2538
P+ +LVHT +T R + +E +++ +P++ VG +G KT + L +LSE+
Sbjct: 2418 HAPERKFINILVHTVDTTRTTWILEQMVKIKQPVIFVGESGTSKTATTQNFLKNLSEETN 2477
Query: 2539 IVSRVPFNYYTTSTALQKILEKPLEKKAGHNYGPGGNKKLIYFIDDMNMPEVDLYGTVQP 2598
IV V F+ TTS +Q+ LE +EK+ YGP K+L+ F+DDMNMP VD YGT QP
Sbjct: 2478 IVLMVNFSSRTTSMDIQRNLEANVEKRTKDTYGPPMGKRLLVFMDDMNMPRVDEYGTQQP 2537
Query: 2599 HTLIRQHIDYGHWYDRQKVM-LKEIHNCQYVACMNPMVGSFT-INPRLQRHFTVFAFNFP 2656
L++ ++ G+ YDR K + K I + ++A M G ++PR F+VF FP
Sbjct: 2538 IALLKLLLEKGYLYDRGKELNCKSIRDLGFIAAMGKAGGGRNEVDPRFISLFSVFNVPFP 2597
Query: 2657 SLDALNTIYGQIFSFHFQQQAFAPSILRSGPTLIQATIAFHQTMMCNFLPTAIKFHYIFN 2716
S ++L+ IY I H F SI+ L T+A ++ ++ + PT KFHYIFN
Sbjct: 2598 SEESLHLIYSSILKGH--TSTFHESIVAVSGKLTFCTLALYKNIVQDLPPTPSKFHYIFN 2655
Query: 2717 LRDLSNVFQGILFASPECLKGPLDLIHLWLHESARVYGDKLIDKKDCDLFQRRMLETAYK 2776
LRDLS VF G++ +PE + ++ +W +E RV+ D+LI + D L Q+ + +
Sbjct: 2656 LRDLSRVFNGLVLTNPERFQTVAQMVRVWRNECLRVFHDRLISETDKQLVQQHIGSLVVE 2715
Query: 2777 YFEGIDSHMLLQQPLIYCHF---ADRGKDPHYMPVKDWEVLKTILTETLDNYNELNAAMH 2833
+F+ D ++++ P+++ F G+ Y ++D+E K + E L+ YNE N M+
Sbjct: 2716 HFKD-DVEVVMRDPILFGDFQMALHEGEPRIYEDIQDYEAAKALFQEILEEYNESNTKMN 2774
Query: 2834 LVLFEDAMQHVCRISRILRTPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYG 2893
LVLF+DA++H+ R+ RI+R +G ALLVGVGGSGKQSLSRLAA+ EVF+I L+ GY
Sbjct: 2775 LVLFDDALEHLTRVHRIIRMDRGHALLVGVGGSGKQSLSRLAAFTASCEVFEILLSRGYS 2834
Query: 2894 IQELRVDLANLYIRTGAKNMPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDK 2953
R DL +LY++ G +N +FL TDA V +E FL LIN++L SG +P LFS+E+ +
Sbjct: 2835 ENSFREDLKSLYLKLGIENKAMIFLFTDAHVAEEGFLELINNMLTSGIVPALFSEEEKES 2894
Query: 2954 IISGIHNEVHALGMVDSRENCWKFFMARVRLQLKIILCFSPVGRTLRVRARKFPAIVNCT 3013
I+S I E GM ++E+ W++F+ + L I+L SPVG TLR R FP +VN T
Sbjct: 2895 ILSQIGQEALKQGMGPAKESVWQYFVNKSANNLHIVLGMSPVGDTLRTWCRNFPGMVNNT 2954
Query: 3014 AIDWFHAWPQEALVSVSRRFIEETKGIEPVHKDSISLFMAHVHTTVNEMSTRYYQNERRH 3073
IDWF WP +AL +V++ F+ I + +++ + VH +V+ S ++ Q RR
Sbjct: 2955 GIDWFMPWPPQALHAVAKSFLGYNPMIPAENIENVVKHVVLVHQSVDHYSQQFLQKLRRS 3014
Query: 3074 NYTTPKSFLEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLASQEAE 3133
NY TPK++L+ I+ + LL +K + +RL G+ KLK Q+ +L +LA Q+
Sbjct: 3015 NYVTPKNYLDFINTYSKLLDEKTQCNIAQCKRLDGGLDKLKEATIQLDELNQKLAEQKIV 3074
Query: 3134 LQLRNHDAEALITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQRECEADLLKAEPA 3193
L ++ EAL+ +I + T +K +A+ + ++ + ++ E E L + P
Sbjct: 3075 LAEKSAACEALLEEIAVNTAVAEEKKKLAEEKAMEIEEQNKVIAMEKAEAETTLAEVMPI 3134
Query: 3194 LVAATAALNTLNRVNLSELKAFPNPPIAVTNVTAAVMVLLAPRGRVPKDRSWKAAKVFMG 3253
L AA L L++ +++E+++F PP V V ++++ + K+ +WK AK M
Sbjct: 3135 LEAAKLELQKLDKSDVTEIRSFAKPPKQVQTVCECILIM-----KGYKELNWKTAKGVMS 3189
Query: 3254 KVDDFLQALINYDKEHIPENCLKVVNEHYLKDPEFNPNLIRTKSFAAAGLCAWVINIIKF 3313
+FL++L+ D + I ++ +K + + LK + S A G+ +V ++ +
Sbjct: 3190 D-PNFLRSLMEIDFDSITQSQVKNI-KGLLKTLNTTTEEMEAVSKAGLGMLKFVEAVMGY 3247
Query: 3314 YEVYCDVEPKRQALAQANLELAAATEKLEAIRKKLVDLDRNLSRLTASFEKATAEKVRCQ 3373
+V+ +++PKR+ +A+ +LE I+ +L + + L L A +E A EK + Q
Sbjct: 3248 CDVFREIKPKREKVARLERNFYLTKRELERIQNELAAIQKELETLGAKYEAAILEKQKLQ 3307
Query: 3374 EEVNQTNKTIKLANRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLLTAAFVSYVGPFTR 3433
EE + + A++L+ L ++ IRW + + L GD LL AAF+SY G FT
Sbjct: 3308 EEAEIMERRLIAADKLISGLGSENIRWLNDLDELMHRRVKLLGDCLLCAAFLSYEGAFTW 3367
Query: 3434 QYRQELVHCKWVPFLQQKVSIPLTEGLDLISMLTDDATIAAWNNEGLPSDRMSTENAAIL 3493
++R E+V+ W + ++ IPL++ L S+LTDD I+ W ++GLP D +S +N +
Sbjct: 3368 EFRDEMVNRIWQNDILER-EIPLSQPFRLESLLTDDVEISRWGSQGLPPDELSVQNGILT 3426
Query: 3494 THCERWPLVIDPQQQGIKWIKNKYGM-DLKVTHLGQKGFLNAIETALAFGDVILIENLEE 3552
T R+PL IDPQQQ + WIK K +L+V FL +E ++ +G L +++E
Sbjct: 3427 TRASRFPLCIDPQQQALNWIKRKEEKNNLRVASFNDPDFLKQLEMSIKYGTPFLFRDVDE 3486
Query: 3553 TIDPVLDPLLGRN-TIKKGK-YIRIGDKECEFNKNFRLILHTKLANPHYKPELQAQTTLL 3610
IDPV+D +L +N + +G+ +I +GDKE +++ NFRL L+TKLANP Y P + + ++
Sbjct: 3487 YIDPVIDNVLEKNIKVSQGRQFIILGDKEVDYDSNFRLYLNTKLANPRYSPSVFGKAMVI 3546
Query: 3611 NFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLEDDLLLRLSAAEGS 3670
N+TVT GLE QLL+ +V+ ER +LE+ + L + ++ K LK LED LL L+ + G+
Sbjct: 3547 NYTVTLKGLEDQLLSVLVAYERRELEEQREHLIQETSENKNLLKDLEDSLLRELATSTGN 3606
Query: 3671 FLDDTKLVERLEATKTTVAEIEHKVIEAKENERKINEARECYRPVAARASLLYFVINDLQ 3730
LD+ LV LE TK+ E+ K+ A++ I+ R+ YRP A R ++L+FV++++
Sbjct: 3607 MLDNVDLVHTLEETKSKATEVSEKLKLAEKTALDIDRLRDGYRPAARRGAILFFVLSEMA 3666
Query: 3731 KINPLYQFSLKAFNVLFHRAIEQADKVEDMQGRISILMESITHAVFLYTSQALFEKDKLT 3790
+N +YQ+SL AF +F +++++ + R+ +M+++T +++ + LFE+ KL
Sbjct: 3667 LVNSMYQYSLIAFLEVFRLSLKKSLPDSILMKRLRNIMDTLTFSIYNHGCTGLFERHKLL 3726
Query: 3791 FLSQMAFQILLRKKEIDPLELDFLLRFTV---EHTHLSPVDFLTSQSWSAIKAIAVM--E 3845
F M +I + + ELDF L+ + + P +L+ Q W I ++ M +
Sbjct: 3727 FSFNMTIKIEQAEGRVPQEELDFFLKGNISLEKSKRKKPCAWLSDQGWEDIILLSEMFSD 3786
Query: 3846 EFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKK-SLIQKLILLRAMRPDRMTYALR 3904
F + DVE + W++W + + E+ +P + + QKL++LR R DR+ A+
Sbjct: 3787 NFGQLPDDVENNQTVWQEWYDLDSLEQFPVPLGYDNNITPFQKLLILRCFRVDRVYRAVT 3846
Query: 3905 NFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEILGKRLGFTIDSG 3964
++V +G KYV+ + FE+S+P +PI FILSPG D DL L +R GF +
Sbjct: 3847 DYVTVTMGEKYVQPPMISFEAIFEQSTPHSPIVFILSPGSDPATDLMKLAERSGFGGNRL 3906
Query: 3965 KFHNVSLGQGQETVAEVALEKASKGGHWVILQNVHLVAKWLGTLEKLLERFSQGSHRDYR 4024
KF +++GQGQE VA LE A G W++LQN HL+ KWL LEK LER ++ H D+R
Sbjct: 3907 KF--LAMGQGQEKVALQLLETAVARGQWLMLQNCHLLVKWLKDLEKSLERITK-PHPDFR 3963
Query: 4025 VFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHAALYNFDQDTLEICSKEQEF 4084
++++ + PT P G+L+ S+K+ EPP G+ N+ A + + L+ C F
Sbjct: 3964 LWLTTD--PTKG---FPIGILQKSLKVVTEPPNGLKLNMRATYFKISHEMLDQC-PHPAF 4017
Query: 4085 KSILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICASVLYNYL-----EANSKVPW 4139
K +++ L +FHA V R +FG GW+ Y FN D +C +L YL + + ++PW
Sbjct: 4018 KPLVYVLAFFHAVVQERRKFGKIGWNVYYDFNESDFQVCMEILNTYLTKAFQQRDPRIPW 4077
Query: 4140 EDLRYLFGEIMYGGHITDDWDRKLCRVYLEEFMNPSLTEDELML------APGFAAPPYL 4193
L+YL GE+MYGG D +DR++ +Y++E++ + + + P
Sbjct: 4078 GSLKYLIGEVMYGGRAIDSFDRRILTIYMDEYLGDFIFDTFQPFHFFRNKEVDYKIPVGD 4137
Query: 4194 DYAGYHQYIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALSGDELGQS 4253
+ + + IE + +P ++GLHPNAEI + T + ++ LLE+QP+ S G S
Sbjct: 4138 EKEKFVEAIEALPLANTPEVFGLHPNAEIGYYTQAARDMWAHLLELQPQTGESSS--GIS 4195
Query: 4254 TEEKVKNVLDDILEKLPEEFNMAEIMQK-NSNRSPYVLVCFQECERMNILIREIRISLEQ 4312
++ + V +I K+P+ F++ ++ ++ + SP +V QE ER N L+ + SL +
Sbjct: 4196 RDDYIGQVAKEIENKMPKVFDLDQVRKRLGTGLSPTSVVLLQELERFNKLVVRMTKSLAE 4255
Query: 4313 LDLSLKGELALSPAVEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRELDTWT 4372
L +L GE+ +S ++ +L +P+ W +LA + L W L R + W
Sbjct: 4256 LQRALAGEVGMSNELDDVARSLFIGHIPNIWRRLAPDTLKSLGNWMVYFLRRFSQYMLWV 4315
Query: 4373 QDLTLPAVVWLSGFFNPQSFLTAIMQTMARKNEWPLDKTRLTADVTK-KTKEDYGHPPRE 4431
+ + P+V+WLSG P+S+LTA++Q RKN WPLD++ L VTK + ++ +
Sbjct: 4316 TE-SEPSVMWLSGLHIPESYLTALVQATCRKNGWPLDRSTLFTQVTKFQDADEVNERAGQ 4374
Query: 4432 GAYLHGLFMEGARWDTQAGTIVEARLKELACPMPVIFAKATPVDRQETKQTYECPVYRTK 4491
G ++ GL++EGA WD + G +++++ K L +P++ R + + T+ PVY T
Sbjct: 4375 GCFVSGLYLEGADWDIEKGCLIKSKPKVLVVDLPILKIIPIEAHRLKLQNTFRTPVYTTS 4434
Query: 4492 LR----GPSYIWTFRLKSEEKTAKWVLAGVALLLEA 4523
+R G ++ L + + WVL GV L L +
Sbjct: 4435 MRRNAMGVGLVFEADLFTTRHISHWVLQGVCLTLNS 4470
>gi|75677365 dynein heavy chain domain 3 [Homo sapiens]
Length = 4427
Score = 2130 bits (5519), Expect = 0.0
Identities = 1464/4608 (31%), Positives = 2311/4608 (50%), Gaps = 359/4608 (7%)
Query: 36 EEEEENEEEAAARRARSFAQDARVRFLGGRLAMMLGFTEEKWSQYLESEDNRQVLGEFLE 95
EE E E A+ S +A V+ L A + G + W+Q ++ +L F +
Sbjct: 53 EEPEPRLEGPQAQSEESVEPEADVKPLFLSRAALTGLADAVWTQ-----EHDAILEHFAQ 107
Query: 96 STSPACLVFSFAASGRLAASQEIPRDANHKLVFISKKITESIGVNDFSQVVLFGELPALS 155
+ + L L +P ++LV+ ++ I +F V FG +
Sbjct: 108 DPTESILTIFIDPCFGLKLELGMPVQTQNQLVYFIRQAPVPITWENFEATVQFGTVRGPY 167
Query: 156 LGHVSAFLDEILVPVLSNKNNHKSWSCFTSQDMEYHIEVMKKKMYIFRGKMSRRTLLPIP 215
+ + L + P + W H+ + R K+ T+L IP
Sbjct: 168 IPALLRLLGGVFAPQIFANTG---WPESIRNHFASHLHKFLACLTDTRYKLEGHTVLYIP 224
Query: 216 TVAGKMDLDQNCSENKPPSNERIILHAIESVVIEWSHQIQEIIERDSVQRLLNGLHLSPQ 275
A M + + + ++ +E+ +I W+ QI+E++ + + G +L P
Sbjct: 225 AEAMNMKPEMVIKDKE-------LVQRLETSMIHWTRQIKEMLSAQ--ETVETGENLGPL 275
Query: 276 AELDFWMMRRENLSCIYDQLQAPVVLKMVKILTTKQSSYFPTLKDIFLAVENALLEAQDV 335
E++FW R +LS I QL V + IL +SSY + AQ +
Sbjct: 276 EEIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPFMKL----------AQQI 325
Query: 336 ELYLRPLRRHIQCLQETEFPQTRILIAPLFHTICLIWSHSKFYNTPARVIVLLQEFCNLF 395
+ R + ++ L + P
Sbjct: 326 QDGSRQAQSNLTFLSILKEPY--------------------------------------- 346
Query: 396 INQATAYLSPEDLLRGEIEESLEKVQVAVNILKTFKNSFFNYRKKLASYFMGRKLRPWDF 455
Q A++ P+D I L K+ + I+ + +N R++L S F RK+ D
Sbjct: 347 --QELAFMKPKD-----ISSKLPKLISLIRIIWV-NSPHYNTRERLTSLF--RKV--CDC 394
Query: 456 QSHLVFCRFD----------------KFLDRLIKIEDIFATTLEFEKLERLEFGGTKGAI 499
Q H F R++ + L++IEDIF L + R G I
Sbjct: 395 QYH--FARWEDGKQGPLPCFFGAQGPQITRNLLEIEDIFHKNLHTLRAVR-------GGI 445
Query: 500 LNGQVHEMSEELMELCKLFKQSTYDPSDCTNMEFESDYVAFKSKTLEFDRRLGTIICEAF 559
L D N + DY F++ + + +I AF
Sbjct: 446 L--------------------------DVKNTCWHEDYNKFRAGIKDLEVMTQNLITSAF 479
Query: 560 FNCNGLEAAFKLLTIFGNFLEKPVVMEIFSLHYSTLVHMFNTELDVCKQLYNEHMKQIEC 619
+ LL F + + + L +FN+EL + + N+ +E
Sbjct: 480 ELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLE- 538
Query: 620 GHVVLNKNMPFT---SGNMKWAQQVLQRLQMFWSNFASLRYL-FLGNPDHALVYQKYVEM 675
P+ SG +W + +R+ + A +L +G ++ Y +M
Sbjct: 539 ---------PYVAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESV--HTYQQM 587
Query: 676 TTLLDQFESRIYNEWKSNVDEICEFNLNQPLVKFSAIN-GLLCVNFDPKLVAVLREVKYL 734
+D+ + + EW S++D+ C L+ PL++ S G+L VNFD L+ + E+ Y
Sbjct: 588 VQAIDELVRKTFQEWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYW 647
Query: 735 LMLKKQDIPDSALAIFKKRNTILKYIGNLDLLVQGYNKLKQTLLEVEYPLIEDELRAIDE 794
L + P + + ++ + NL L+ + YN++ L E L ++ +R +D+
Sbjct: 648 ERLLFET-PHYVVNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDK 706
Query: 795 QLTAATTWLTWQ---------DDCWGYIERV-------RAATSELEHRVERTQKNVKVIQ 838
++ L W +C + +V +A+T + R + + + V
Sbjct: 707 KIHPGLKKLHWALKGASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRI 766
Query: 839 QTMRGWARCVLPP-RREHRREAAFTL----EDKGDLFTKKYKLIQGDGCKIHNLVEENRK 893
R + +REHR L +D + T Y++ + DG +I
Sbjct: 767 SGKRVYRDLEFEEDQREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQ------- 819
Query: 894 LFKANPSLDTWKIYVEFIDDIVVEGFFQAIMHDLDFFLK--NTEKQLKPAPFFQAQMILL 951
W +Y+ +D ++ + + L K N + + P P FQ +IL
Sbjct: 820 ---------QWMLYMIRLDRMMEDALRLNVKWSLLELSKAINGDGKTSPNPLFQVLVILK 870
Query: 952 PP------EIVFKPSLDREAGDGFYDLVEEMLCNSFRMSAQMNRIATHLEIKN--YQNDM 1003
++ F P+L AG + + L ++ + + I T ++ Q +
Sbjct: 871 NDLQGSVAQVEFSPTLQTLAG--VVNDIGNHLFSTISVFCHLPDILTKRKLHREPIQTVV 928
Query: 1004 DNMLGLAEVRQEIMNRVVNVINKVLDFRNTLETHTYLWVDDRAEFMKHFLLYGHAVSSDE 1063
+ + +++ +I + + N + + ++ T + + +W ++ F+ + VSS
Sbjct: 929 EQDEDIKKIQTQISSGMTNNASLLQNYLKTWDMYREIWEINKDSFIHRYQRLNPPVSSFV 988
Query: 1064 MDAHANEEIPEQPPTLEQFKEQIDIYEALYVQMSKFEDFRVFDSWFKVDMKPFKVSLLTI 1123
D E+ Q +E + + + + D K SL+
Sbjct: 989 ADIARYTEVANNV----QKEETVTNIQFVLL-----------------DCSHLKFSLVQH 1027
Query: 1124 IKKWSWMFQEHLLRFVIDSLNELQEFIKETDSGLQRELNEGDHDG----LVDIMVHLLAV 1179
+W F L L EL ++KE + R + G LVD + H LA
Sbjct: 1028 CNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDALKHDLAN 1087
Query: 1180 RSRQRATDELFEPLKETITLLESYGQKMPEQVYIQLEELPERWETTKKIAATVRHEVSPL 1239
Q P+ E +LE Y + + V L+ L W ++ + +
Sbjct: 1088 VETQ------IPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKH 1141
Query: 1240 HNAEVTLIRKKCILFDAKQAEFRERFRHYAPLGFNAENPYTALDKANEE---LEALEEEM 1296
T + F K E F N +ALD+ + L A+ EE
Sbjct: 1142 KEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNV-GYMSALDQITQVRAMLMAMREEE 1200
Query: 1297 LQMQESTRLFEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTKTQWRQIHVEQM 1356
++ + +F++ P K ++ KE+ L+ +W++ R +NW +W+ +
Sbjct: 1201 NSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEI---ARDWEENWN--EWKTGRFLIL 1255
Query: 1357 DVELRRFAKASSITEIWSLNKEV--RVWDAYTGLEGTVKDMTASLRAITELQSPALRDRH 1414
E + L KE R W+ ++ ++ I++L++PALR+RH
Sbjct: 1256 QTETMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERH 1315
Query: 1415 WHQLMKAIGVKF-LINEATTLADLLALRLHRVEDDVRRIVDKAVKELGTEKVITEISQTW 1473
W Q+ I +F +E+ TL ++ L + + + + I A KEL E + I++TW
Sbjct: 1316 WDQVRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTW 1375
Query: 1474 ATMKFSYEVHYRTGIPLLKSDEQLFETLEHNQVQLQTLLQSKYVEYFIEQVLSWQNKLNI 1533
+ + G L+ E++F+ LE NQV L T+ S++V+ F + V W+ L++
Sbjct: 1376 DVTQLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSL 1435
Query: 1534 ADLVIFTWMEVQRTWSHLESIFVCSEDIRIQLVKDARRFDGVDAEFKELMFKTAKVENVL 1593
VI + VQR W +LE+IF+ EDIR QL ++ FD V++ +K +M + K N L
Sbjct: 1436 ILEVIEMILTVQRQWMYLENIFL-GEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNAL 1494
Query: 1594 EATCRPNLYEKLKDLQSRLSLCEKALAEYLETKRIAFPRFYFVSSADLLDILSKGAQPKQ 1653
+T P L + L ++ + L +K+L YLETKR FPRFYF+S+ DLL+IL + P+
Sbjct: 1495 RSTHHPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEA 1554
Query: 1654 VTCHLAKLFDSIADLQFEDNQDVSAH-RAVGMYSKEKEYVPFQAECECVGHVETWLLQLE 1712
V HL K FD+I L+ + S+ AVGM+S + EY+ F G VE+WL +E
Sbjct: 1555 VQPHLKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVE 1614
Query: 1713 QTMQETVRHSITEAIVAYEE--KPRELWIFDFPAQVALTSSQIWWTTDVG-IAFSRLEEG 1769
QTM+ T+R + +A + R+ W+ ++ QV +T+SQI WT DV + E
Sbjct: 1615 QTMRVTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERA 1674
Query: 1770 YETALKDFHKKQISQLNTLITLLLGELPPGDRQKIMTICTIDVHARDVVAKLISQKQVVV 1829
+ LK K Q+S LN + G L R KI+ + TI++HARDV+ KL K ++
Sbjct: 1675 DKKILKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLY--KSGLM 1732
Query: 1830 SPQAFTWLSQLRHRWEDTQKHCFVNICDAQFQYFYEYLGNSPRLVITPLTDRCYITLTQS 1889
+F WLSQLR WE C + + QFQY YEYLGNS RLVITPLTDRCY+TLT +
Sbjct: 1733 DVNSFDWLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTA 1792
Query: 1890 LHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGAWG 1949
LHL G+P GPAGTGKTET KDLG+ALG+ V V NCSE +DYKS+G +Y GL QTGAWG
Sbjct: 1793 LHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWG 1852
Query: 1950 CFDEFNRISVEVLSVVAVQVKMIHDAIRNRKKRFVFLGEAITLKPSVGIFITMNPGYAGR 2009
CFDEFNRI++EVLSVVA Q+ I A+ F F G I L S GIFITMNPGYAGR
Sbjct: 1853 CFDEFNRINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGR 1912
Query: 2010 TELPENLKALFRPCAMVAPDIELICEILLVAEGFVDARALARKFITLYTLCKELLSKQDH 2069
TELPENLK++FRP AMV PD LI EI+L EGF + + LA+K TLY+L + LS+QDH
Sbjct: 1913 TELPENLKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDH 1972
Query: 2070 YDWGLRAIKSVLVVAGSLKRGDKNRPEDQVLMRALRDFNMPKIVTDDIPVFLGLVGDLFP 2129
YD+GLRA+ S+L AG +R + +++VL+ ++RD N+ K+ + D P+F +V DLFP
Sbjct: 1973 YDFGLRALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFP 2032
Query: 2130 ALDVPRRRKLHFEQMVRQSTLELRLQPEESFILKVVQLEELLAVRHSVFVVGNAGTGKSK 2189
+++P + V Q ++ LQ + KV QL E RHS +VG G+GK+
Sbjct: 2033 NIELPVIDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTA 2092
Query: 2190 ILRTLNRTYVNMKQ--KPVWN-----DLNPKAVTTDELFGFIHHATREWKDGKIVYSYFI 2242
R L + ++ + P +N LNPKA++ EL+G +T EW D
Sbjct: 2093 SWRILQASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTD--------- 2143
Query: 2243 GLFSSILREQANLKHDGPKWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIALTPFMR 2302
G+ SS++R + KWI+ DG +D +WIE++N+VMDDNKVLTL + ERIA+ +
Sbjct: 2144 GILSSVMRTACADEKPDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVS 2203
Query: 2303 LLFEIHHLRSATPATVSRAGILYVNPQDLGWNPYVASWIDRRRHQSEKANLTILFDKYVP 2362
LLFE+ L A+PATVSR G++Y + DLGW PYV SW++ +R ++E L +F+K +
Sbjct: 2204 LLFEVEDLAMASPATVSRCGMVYTDYADLGWKPYVQSWLE-KRPKAEVEPLQRMFEKLIN 2262
Query: 2363 ACLDKLRTSFKTITSIPESSLVQTLCVLLECLLTPENVPSDSPKEVY----EVYFVFACI 2418
L + + K + +PE S + +LC L L TPEN + + E Y E+ FVF+ I
Sbjct: 2263 KMLAFKKDNCKELVPLPEYSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMI 2322
Query: 2419 WAFGGTLLQD---QISDYQADFSRWWQKEMKAVKFPSQGTIFDYYVDHKTKKLLPWADKI 2475
W+ ++ ++ +I Y + FP++ T+++Y+VD K + + DK+
Sbjct: 2323 WSVCASVDEEGRKRIDSYLREIEG---------SFPNKDTVYEYFVDPKIRSWTSFEDKL 2373
Query: 2476 AQ-FTMDPDVPLQTVLVHTTETARLRYFMELLLEKGKPLMLVGNAGVGKTVFVGDTLASL 2534
+ + P+ P ++V T +T R Y + L+ P++LVG G GKT L SL
Sbjct: 2374 PKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSL 2433
Query: 2535 -SEDYIVSRVPFNYYTTSTALQKILEKPLEKKAGHNYGPGGNKKLIYFIDDMNMPEVDLY 2593
S + V V + TTS +Q I+E +EK+ Y P G K +I F+DD+NMP D++
Sbjct: 2434 PSSQWSVLVVNMSAQTTSNNVQSIIESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMF 2493
Query: 2594 GTVQPHTLIRQHIDYGHWYDRQKVMLKEIHNCQYVACMNPMVGSFT-INPRLQRHFTVFA 2652
G+ P LIR IDYG WYDR K +K I +A M P G T I+PRL+ F +
Sbjct: 2494 GSQPPLELIRLWIDYGFWYDRTKQTIKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIIN 2553
Query: 2653 FNFPSLDALNTIYGQIFSFHFQQQAFAPSILRSGPTLIQATIAFHQTMMCNFLPTAIKFH 2712
FP+ + I+G + + Q F + G + +AT+ + T++ FLPT K H
Sbjct: 2554 MTFPTKSQIIRIFGTMINQKLQD--FEEEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMH 2611
Query: 2713 YIFNLRDLSNVFQGILFASPECLKGPLDLIHLWLHESARVYGDKLIDKKDCDLFQRRMLE 2772
Y+FNLRD+S VFQG+L A+ + + LW+HE RV+ D+L+D D + F + +
Sbjct: 2612 YLFNLRDISKVFQGMLRANKDFHDTKSSITRLWIHECFRVFSDRLVDAADTEAFMGIISD 2671
Query: 2773 TAYKYFEGIDSHML-LQQPLIYCHFADRGKDPH-YMPVKDWEVLKTILTETLDNYNELNA 2830
+F+ H+ ++P I F D K+P Y + D VLKT++ L+ YN +
Sbjct: 2672 KLGSFFDLTFHHLCPSKRPPI---FGDFLKEPKVYEDLTDLTVLKTVMETALNEYNLSPS 2728
Query: 2831 A--MHLVLFEDAMQHVCRISRILRTPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITL 2888
M LVLF +A++H+ RI R++ P+G LLVG+GGSG+QSL+RLA+ + FQI +
Sbjct: 2729 VVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLARLASSICDYTTFQIEV 2788
Query: 2889 TEGYGIQELRVDLANLYIRTGAKNMPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSD 2948
T+ Y QE R D+ LY + G + T F+ D Q+ DESFL IN++L+SGE+P+L+
Sbjct: 2789 TKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIADESFLEDINNILSSGEVPNLYKP 2848
Query: 2949 EDVDKIISGIHNEVHALGMVDSRENCWKFFMARVRLQLKIILCFSPVGRTLRVRARKFPA 3008
++ ++I S I ++ + +S ++ + + + RV+ L I+LC SP+G R R++PA
Sbjct: 2849 DEFEEIQSHIIDQARVEQVPESSDSLFAYLIERVQNNLHIVLCLSPMGDPFRNWIRQYPA 2908
Query: 3009 IVNCTAIDWFHAWPQEALVSVSRRFI--EETKGIEPVHKDSISLFMAHVHTTVNEMSTRY 3066
+VNCT I+WF WPQEAL+ V+ + + + E +H+ +F+ +H +V + S +
Sbjct: 2909 LVNCTTINWFSEWPQEALLEVAEKCLIGVDLGTQENIHRKVAQIFVT-MHWSVAQYSQKM 2967
Query: 3067 YQNERRHNYTTPKSFLEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKAR 3126
RRHNY TP +LE +S +K LL +K+ E+ + +L G+ K+ T +V
Sbjct: 2968 LLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTGLFKIDETREKV------ 3021
Query: 3127 LASQEAELQLRNHDAEALITKIGLQTEK----VSREKTIADAEERKVTAIQTEVFQKQRE 3182
Q L+L DA+ + + Q E+ + ++K AD +++ VTA ++ ++ +
Sbjct: 3022 ---QVMSLEL--EDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIAVEEIK 3076
Query: 3183 CEA-------DLLKAEPALVAATAALNTLNRVNLSELKAFPNPPIAVTNVTAAVMVLLAP 3235
C+A DL +A PAL A AL +LN+ ++ E+K++ PP V V AVM+L
Sbjct: 3077 CQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAVMIL--- 3133
Query: 3236 RGRVPKDRSWKAAKVFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLKDPEFNPNLIRT 3295
RG P +W AK +G+ +F+++LIN+DK++I + LK + Y P+F P++I
Sbjct: 3134 RGNEP---TWAEAKRQLGE-QNFIKSLINFDKDNISDKVLKKIGA-YCAQPDFQPDIIGR 3188
Query: 3296 KSFAAAGLCAWVINIIKFYEVYCDVEPKRQALAQANLELAAATEKLEAIRKKLVDLDRNL 3355
S AA LC WV + + +Y VEPKR + A +L L ++KL ++ L
Sbjct: 3189 VSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREVAEKL 3248
Query: 3356 SRLTASFEKATAEKVRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSIKSFEAQEKTLC 3415
L +++ A+K +++ + ++ A LV L +K RW ++++ E L
Sbjct: 3249 EMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLV 3308
Query: 3416 GDVLLTAAFVSYVGPFTRQYRQELVHCKWVPFLQQKVSIPLTEGLDLISMLTDDATIAAW 3475
GD LL AAF+SY+GPF YR E+V+ W+ + + + +P + + + L + + W
Sbjct: 3309 GDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWE-LQVPCSPSFAIDNFLCNPTKVRDW 3367
Query: 3476 NNEGLPSDRMSTENAAILTHCERWPLVIDPQQQGIKWIKN-KYGMDLKVTHLGQKGFLNA 3534
N +GLPSD STEN I+T RW L+IDPQ Q +KWIKN + G LK+ L +L
Sbjct: 3368 NIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQMSDYLRI 3427
Query: 3535 IETALAFGDVILIENLEETIDPVLDPLLGRNTIKKG--KYIRIGDKECEFNKNFRLILHT 3592
+E A+ FG +L++N++E +DP L+P+L ++ + G +RIGDKE E+N NFR + T
Sbjct: 3428 LEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFYITT 3487
Query: 3593 KLANPHYKPELQAQTTLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIE 3652
KL+NPHY PE A+TT++NF V E GLEAQLL VV ERP+LE+ K L + K +
Sbjct: 3488 KLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGKRK 3547
Query: 3653 LKYLEDDLLLRLSAAEGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENERKINEARECY 3712
LK LED++L L+ A GS LDD +LV L +K T E+ ++ ++ E + ARE Y
Sbjct: 3548 LKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLAREAY 3607
Query: 3713 RPVAARASLLYFVINDLQKINPLYQFSLKAFNVLFHRAIEQADKVEDMQGRISILMESIT 3772
RP A RAS+L+FV+ND+ I+P+YQFSL A+ LF +I+++ + ++ RI L + T
Sbjct: 3608 RPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLNDYHT 3667
Query: 3773 HAVFLYTSQALFEKDKLTFLSQMAFQILLRKKEIDPLELDFLLRFTVEHTHLSPVD---- 3828
+AV+ YT + LFE+ KL F M +IL +++ E +F LR V +D
Sbjct: 3668 YAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREGQMDNPCS 3727
Query: 3829 -FLTSQSWSAIKAIAVMEEFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKK-SLIQ 3886
+L W I + + F G+ E + W W + PEK LP EW+ + +Q
Sbjct: 3728 SWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENACNEMQ 3787
Query: 3887 KLILLRAMRPDRMTYALRNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDA 3946
+++++R++R DR+ + + +F+ LG++++E L++ E+S+P +P+ FILSPGVD
Sbjct: 3788 RMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPGVDP 3847
Query: 3947 LKDLEILGKRLGFTIDSGKFHNVSLGQGQETVAEVALEKASKGGHWVILQNVHLVAKWLG 4006
L L + +G + +FH +SLGQGQ +A L + GHWV L N HL W+
Sbjct: 3848 TSALLQLAEHMGM---AQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMP 3904
Query: 4007 TLEKLLERFS-QGSHRDYRVFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHA 4065
L+KL+E+ + H +R+++S S P PD P +L+ SIK+T EPP G+ AN+
Sbjct: 3905 NLDKLVEQLQVEDPHPSFRLWLS--SIPHPD---FPISILQVSIKMTTEPPKGLKANMTR 3959
Query: 4066 ALYNFDQDTLEICSKEQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICAS 4125
+ CSK ++K +LFSLC+FH+ + R +F GW+ Y FN D + +
Sbjct: 3960 LYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSEN 4019
Query: 4126 VLYNYLEANSKVPWEDLRYLFGEIMYGGHITDDWDRKLCRVYLEE-FMNPSLTE--DELM 4182
+L YL+ + PW+ L+YL I YGGH+TDDWDR+L Y+ + F + SL+ L
Sbjct: 4020 LLSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLS 4079
Query: 4183 LAPGFAAPPYLDYAGYHQYIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPR 4242
+ P A Y +YI + + P +G HPNA++ + TLF TLL +QP+
Sbjct: 4080 ALETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQ 4139
Query: 4243 NALSGDELGQSTEEKVKNVLDDILEKLPEEFNMAEIMQK--NSNRSPYVLVCFQECERMN 4300
+ GQ+ EEKV + D+ +K+PE + E QK + SP +V QE +R N
Sbjct: 4140 ITPTRAG-GQTREEKVLELAADVKQKIPEMIDY-EGTQKLLALDPSPLNVVLLQEIQRYN 4197
Query: 4301 ILIREIRISLEQLDLSLKGELALSPAVEAQQFALSYDT-VPDTWSKLAYPSTYGLAQWFN 4359
L++ I SL L+ ++G + +S ++E + F +D VP W K AYPS LA W
Sbjct: 4198 TLMQTILFSLTDLEKGIQGLIVMSTSLE-EIFNCIFDAHVPPLWGK-AYPSQKPLAAWTR 4255
Query: 4360 DLLLRCRELDTWTQDLTLPAVVWLSGFFNPQSFLTAIMQTMARKNEWPLDKTRLTADVTK 4419
DL +R + + W P + WLSGF P FLTA++Q+ AR+N +D V+
Sbjct: 4256 DLAMRVEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVST 4315
Query: 4420 KTKEDYGHPPREGAYLHGLFMEGARWDTQAGTIVEARLKELACPMPVIFAKATPVDRQET 4479
+ +PP++G ++ GL++EGA WD + +VEA +L C MP I + ++
Sbjct: 4316 VDDSNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSA 4375
Query: 4480 KQTYECPVYRTKLRG-----PSYIWTFRLKSEEKTA-KWVLAGVALLL 4521
K Y CP Y R S++ L+S T W+ G ALL+
Sbjct: 4376 KGMYSCPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLM 4423
>gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]
Length = 4265
Score = 2000 bits (5182), Expect = 0.0
Identities = 1198/3462 (34%), Positives = 1887/3462 (54%), Gaps = 182/3462 (5%)
Query: 1176 LLAVRSRQRATDELFEPLKETITLLESYGQKMPEQVY-IQLEELPERWETTK---KIAAT 1231
L +R + E L+E I + Q M E +Y + ++ ++W + KI
Sbjct: 864 LAELREWMKGIPERLVGLEERIVKVMDDYQVMDEFLYNLSSDDFNDKWIASNWPSKILGQ 923
Query: 1232 VRHEVSPLHNAEVTLIRKKCILFDAKQAEFRERFR--HYAPLGFNAENPYTALDKANEEL 1289
+ V H + RK I+ Q F+E+ GF+ + + E+
Sbjct: 924 IEL-VQQQHVEDEEKFRKIQIM---DQNNFQEKLEGLQLVVAGFSIHVEISRAHEIANEV 979
Query: 1290 EALEEEMLQMQEST-------RLFEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDN 1342
+++++ Q+ R+F + + Y ++ + KE + LW R ++
Sbjct: 980 RRVKKQLKDCQQLAMLYNNRERIFSLPITNYDKLSRMVKEFQPYLDLWTTASDWLRWSES 1039
Query: 1343 WTKTQWRQIHVEQMDVELRRFAKASSITEIWSLNKEVRVWDAYTGLEGTVKDMTASLRA- 1401
W I EQ++ + K +++K V+ + + D+ A +
Sbjct: 1040 WMNDPLSAIDAEQLEKNVVEAFK--------TMHKCVKQFKDMPACQEVALDIRARIEEF 1091
Query: 1402 ------ITELQSPALRDRHWHQLMKAIGVKFLINEATTLADLLALRLHRVEDDVRRIVDK 1455
I L++P +R RHW L I + T A L + L + + ++ +
Sbjct: 1092 KPYIPLIQGLRNPGMRIRHWETLSNQININVRPKANLTFARCLEMNLQDHIESISKVAEV 1151
Query: 1456 AVKELGTEKVITEISQTWATMKFSYEVHYRTGIPLLKSDEQLFETLEHNQVQLQTLLQSK 1515
A KE E+ + ++ + W+T+ F+ + T +LKS ++ + L+ + V Q + S
Sbjct: 1152 AGKEYAIEQALDKMEKEWSTILFNVLPYKATDTYILKSPDEASQLLDDHIVMTQNMSFSP 1211
Query: 1516 YVEYFIEQVLSWQNKLNIADLVIFTWMEVQRTWSHLESIFVCSEDIRIQLVKDARRFDGV 1575
Y + F +++ SW+NKL + V+ W+ QR+W +LE IF SEDI QL +++R+ +
Sbjct: 1212 YKKPFEQRINSWENKLKLTQEVLEEWLNCQRSWLYLEPIF-SSEDINQQLPVESKRYQTM 1270
Query: 1576 DAEFKELMFKTAKVENVLEATCRPNLYEKLKDLQSRLSLCEKALAEYLETKRIAFPRFYF 1635
+ +K++M + V+ + + L+D L L +K L+EYLETKR AFPRFYF
Sbjct: 1271 ERIWKKIMKNAYENREVINVCSDLRMLDSLRDCNKILDLVQKGLSEYLETKRSAFPRFYF 1330
Query: 1636 VSSADLLDILSKGAQPKQVTCHLAKLFDSIADLQFEDNQDVSAHRAVGMYSKEKEYVPFQ 1695
+S +LL+ILS+ P V HL K F++IA L F+++ +++ MYS E E V
Sbjct: 1331 LSDDELLEILSQTKDPTAVQPHLRKCFENIARLLFQEDLEITH-----MYSAEGEEVQLC 1385
Query: 1696 AECECVGHVETWLLQLEQTMQETVRHSITEAIVAYEEKPRELWIFDFPAQVALTSSQIWW 1755
+VE WL ++E++M+ +V I +AI AY PR W+ ++P QV + Q +W
Sbjct: 1386 FSIYPSSNVEDWLREVERSMKASVHDIIEKAIRAYPTMPRTQWVLNWPGQVTIAGCQTYW 1445
Query: 1756 TTDVGIAFSRLEEGYETALKDFHKKQISQLNTLITLLLGELPPGDRQKIMTICTIDVHAR 1815
T +V A LE G + QL+ L+ L+ G+L R + + I+VHA+
Sbjct: 1446 TMEVAEA---LEAG--NLRSQLFPQLCQQLSDLVALVRGKLSRMQRAVLSALIVIEVHAK 1500
Query: 1816 DVVAKLISQKQVVVSPQAFTWLSQLRHRWEDTQKHCFVNICDAQFQYFYEYLGNSPRLVI 1875
DVV+KLI + VVS F W+SQLR+ W T ++ +A+F Y YEYLGNS RLVI
Sbjct: 1501 DVVSKLIQEN--VVSVNDFQWISQLRYYW--TNNDLYIRAVNAEFIYGYEYLGNSGRLVI 1556
Query: 1876 TPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDYKSI 1935
TPLTDRCY+TLT +LHL GAPAGPAGTGKTETTKDLG+AL + VFNCS+Q+D+ ++
Sbjct: 1557 TPLTDRCYLTLTGALHLKFGGAPAGPAGTGKTETTKDLGKALAIQTVVFNCSDQLDFMAM 1616
Query: 1936 GNIYKGLVQTGAWGCFDEFNRISVEVLSVVAVQVKMIHDAIRNRKKRFVFLGEAITLKPS 1995
G +KGL GAW CFDEFNRI +EVLSVVA Q+ I A + R +RF+F G I L PS
Sbjct: 1617 GKFFKGLASAGAWACFDEFNRIDIEVLSVVAQQITTIQKAQQQRVERFMFEGVEIPLVPS 1676
Query: 1996 VGIFITMNPGYAGRTELPENLKALFRPCAMVAPDIELICEILLVAEGFVDARALARKFIT 2055
+FITMNPGYAGRTELP+NLKALFRP AM+ PD +I EI L + GF +A LA+K T
Sbjct: 1677 CAVFITMNPGYAGRTELPDNLKALFRPVAMMVPDYAMITEISLYSFGFNEASVLAKKITT 1736
Query: 2056 LYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDKNRPEDQVLMRALRDFNMPKIVTD 2115
+ L E LS QDHYD+G+RA+K+V+ AG+LKR + + E+ + +RA+RD N+PK + +
Sbjct: 1737 TFKLSSEQLSSQDHYDFGMRAVKTVISAAGNLKRENPSMNEELICLRAIRDVNVPKFLQE 1796
Query: 2116 DIPVFLGLVGDLFPALDVPRRRKLHFEQMVRQSTLELRLQPEESFILKVVQLEELLAVRH 2175
D+ +F G+V DLFP + ++ +R++ L+ E F+ K +QL E VRH
Sbjct: 1797 DLKLFSGIVSDLFPTIKEEDTDYGILDEAIREACRNSNLKDVEGFLTKCIQLYETTVVRH 1856
Query: 2176 SVFVVGNAGTGKSKILRTLNRTYVNMKQKPV----------WNDLNPKAVTTDELFGFIH 2225
+ +VG G+GKS R L ++K +P + LNPK++T +L+G
Sbjct: 1857 GLMLVGPTGSGKSTCYRVLAAAMTSLKGQPSISGGMYEAVNYYVLNPKSITMGQLYGEFD 1916
Query: 2226 HATREWKDGKIVYSYFIGLFSSILREQANLKHDGPKWIVLDGDIDPMWIESLNTVMDDNK 2285
T EW D G+FSS +R A KW + DG +D +WIE++NTV+DDNK
Sbjct: 1917 LLTHEWTD---------GIFSSFIRAGAITSDTNKKWYMFDGPVDAIWIENMNTVLDDNK 1967
Query: 2286 VLTLASNERIALTPFMRLLFEIHHLRSATPATVSRAGILYVNPQDLGWNPYVASWIDRRR 2345
L L+S E I LT M ++FE+ L A+PATVSR G++Y+ P LG P++ W+ +
Sbjct: 1968 KLCLSSGEIIKLTEAMTMMFEVQDLAVASPATVSRCGMVYLEPSILGLMPFIECWLRKLP 2027
Query: 2346 H--QSEKANLTILFDKYVPACLDKLRTSFKTITSIPESSLVQTLCVLLECLLTP------ 2397
+ + + LF ++ + +R+S K + + +L +L LL+C P
Sbjct: 2028 PLLKPYEEHFKALFVSFLEESISFVRSSVKEVIASTNCNLTMSLLKLLDCFFKPFLPREG 2087
Query: 2398 -ENVPSDSPK---EVYEVYFVFACIWAFGGTLLQDQISDYQADFSRW----WQKEMKAVK 2449
+ +PS+ E+ E +F+F+ IW+ G T S + FS W + E +
Sbjct: 2088 LKKIPSEKLSRIVELIEPWFIFSLIWSVGAT----GDSSGRTSFSHWLRLKMENEQLTLL 2143
Query: 2450 FPSQGTIFDYYV----------------DHKTKKLLPWADKIAQFTMDPDVPLQTVLVHT 2493
FP +G +FDY + ++K + W D A FTM PD ++V T
Sbjct: 2144 FPEEGLVFDYRLEDAGISGTNDSEDEEEEYKQVAWVKWMDSSAPFTMVPDTNYCNIIVPT 2203
Query: 2494 TETARLRYFMELLLEKGKPLMLVGNAGVGKTVFVGD-TLASLSEDYIVSRVPFNYYTTST 2552
+T ++ + +++LL KP++ +G G GKT+ + D L +L+ DYI + F+ T++
Sbjct: 2204 MDTVQMSHLLDMLLTNKKPVLCIGPTGTGKTLTISDKLLKNLALDYISHFLTFSARTSAN 2263
Query: 2553 ALQKILEKPLEKKAGHNYGPGGNKKLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWY 2612
Q ++ L+K+ +GP + I+FIDD+NMP ++ YG P L+RQ +D+G WY
Sbjct: 2264 QTQDFIDSKLDKRRKGVFGPPLGRNFIFFIDDLNMPALETYGAQPPIELLRQWMDHGGWY 2323
Query: 2613 DRQKV-MLKEIHNCQYVACMNPMVGS-FTINPRLQRHFTVFAF----NFPSLDALNTIYG 2666
DR+ + K + + +V M P G T+ PRL RHF +F +TI G
Sbjct: 2324 DRKIIGAFKNLVDINFVCAMGPPGGGRNTVTPRLMRHFNYLSFAEMDEVSKKRIFSTILG 2383
Query: 2667 QIFSFHFQQQAF------APSILRSGPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDL 2720
++++ AP I L++ATI + T+ LPT K HY FNLRDL
Sbjct: 2384 NWLDGLLGEKSYRERVPGAPHIAHFTEPLVEATIMVYATITSQLLPTPAKSHYTFNLRDL 2443
Query: 2721 SNVFQGILFASPECLKGPLDLIHLWLHESARVYGDKLIDKKDCDLFQRRMLETAYKYFEG 2780
S VFQG+L A P ++ + L+ LW HE+ RV+ D+L++++D F ++L+ + +E
Sbjct: 2444 SKVFQGMLMADPAKVEDQVQLLRLWYHENCRVFRDRLVNEEDRSWFD-QLLKRCMEQWEV 2502
Query: 2781 IDSHMLLQQPLIYCHFADRGKDPHYMPVKDWEVLKT------ILTETLDNYNELNAA-MH 2833
+ + QP++Y F G D VK +E++ + ++ E +++YN++N A +
Sbjct: 2503 TFNKVCPFQPILYGDFMSPGSD-----VKSYELITSESKMMQVIEEYIEDYNQINTAKLK 2557
Query: 2834 LVLFEDAMQHVCRISRILRTPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYG 2893
LVLF DAM H+CRISR LR G ALL+GVGGSG+ SL+RLA+++ E FQI L++ YG
Sbjct: 2558 LVLFMDAMSHICRISRTLRQALGNALLLGVGGSGRSSLTRLASHMAEYECFQIELSKNYG 2617
Query: 2894 IQELRVDLANLYIRTGAKNMPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDK 2953
+ E R D+ + ++ G +N+P FL +D Q+ +ESFL IN++L SG+IP+L++ ++ D+
Sbjct: 2618 MSEWRDDVKKVLLKAGLQNLPITFLFSDTQIKNESFLEDINNVLNSGDIPNLYTADEQDQ 2677
Query: 2954 IISGIHNEVHALGMVDSRENCWKFFMARVRLQLKIILCFSPVGRTLRVRARKFPAIVNCT 3013
I+S + + G+ ++ N + RVR + ++LC SP+G R R R+FP++VNC
Sbjct: 2678 IVSTMRPYIQEQGLQPTKANLMAAYTGRVRSNIHMVLCMSPIGEVFRARLRQFPSLVNCC 2737
Query: 3014 AIDWFHAWPQEALVSVSRRFIEETKGIEPVHKDSISLFM--AHVHTTVNEMSTRYYQNER 3071
IDWF+ WP EAL SV+ F+ E +E ++ L ++H +V++ Y
Sbjct: 2738 TIDWFNEWPAEALKSVATVFLNEIPELESSQEEIQGLIQVCVYIHQSVSKKCIEYLAELT 2797
Query: 3072 RHNYTTPKSFLEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLASQE 3131
RHNY TPKS+LE + +F L+ +K+ E+ K R+ +G+ KL T+ V ++ L S
Sbjct: 2798 RHNYVTPKSYLELLHIFSILIGQKKLELKTAKNRMKSGLDKLLRTSEDVAKMQEDLESMH 2857
Query: 3132 AELQLRNHDAEALITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQRECEADLLKAE 3191
L+ D + +I + T + EE K + + + DL +A
Sbjct: 2858 PLLEEAAKDTMLTMEQIKVDTAIAEETRNSVQTEEIKANEKAKKAQAIADDAQKDLDEAL 2917
Query: 3192 PALVAATAALNTLNRVNLSELKAFPNPPIAVTNVTAAVMVLLAPRGRVPK---------- 3241
PAL AA A+L LN+ +++E++A PP V V AV ++ +G PK
Sbjct: 2918 PALDAALASLRNLNKNDVTEVRAMQRPPPGVKLVIEAVCIM---KGIKPKKVPGEKPGTK 2974
Query: 3242 -DRSWKAAKVFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLKDPEFNPNLIRTKSFAA 3300
D W+ K + FL++L +DK++I + +K + + Y+ + EF P I S A
Sbjct: 2975 VDDYWEPGKGLLQDPGHFLESLFKFDKDNIGDVVIKAI-QPYIDNEEFQPATIAKVSKAC 3033
Query: 3301 AGLCAWVINIIKFYEVYCDVEPKRQALAQANLELAAATEKLEAIRKKLVDLDRNLSRLTA 3360
+C WV + K++ V VEPKRQAL +A +L L+ +++L +++ ++ + A
Sbjct: 3034 TSICQWVRAMHKYHFVAKAVEPKRQALLEAQDDLGVTQRILDEAKQRLREVEDGIATMQA 3093
Query: 3361 SFEKATAEKVRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLL 3420
+ + +K + + Q + + A +L+ L +K+RW +++++ + + GDVL+
Sbjct: 3094 KYRECITKKEELELKCEQCEQRLGRAGKLINGLSDEKVRWQETVENLQYMLNNISGDVLV 3153
Query: 3421 TAAFVSYVGPFTRQYRQELVHCKWVPFLQQKVSIPLTEGLDLISMLTDDATIAAWNNEGL 3480
A FV+Y+GPFT QYR +++ WV L+ ++P T LI L + I +W GL
Sbjct: 3154 AAGFVAYLGPFTGQYR-TVLYDSWVKQLRSH-NVPHTSEPTLIGTLGNPVKIRSWQIAGL 3211
Query: 3481 PSDRMSTENAAILTHCERWPLVIDPQQQGIKWIKN-KYGMDLKVTHLGQKGFLNAIETAL 3539
P+D +S EN I +RW IDPQ Q KWIKN + L V L + FL ++E A+
Sbjct: 3212 PNDTLSVENGVINQFSQRWTHFIDPQSQANKWIKNMEKDNGLDVFKLSDRDFLRSMENAI 3271
Query: 3540 AFGDVILIENLEETIDPVLDPLLGRNTIKK--GKYIRIGDKECEFNKNFRLILHTKLANP 3597
FG L+EN+ E +DP L+P+L + T K+ +++GD ++++FR+ + TKL NP
Sbjct: 3272 RFGKPCLLENVGEELDPALEPVLLKQTYKQQGNTVLKLGDTVIPYHEDFRMYITTKLPNP 3331
Query: 3598 HYKPELQAQTTLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLE 3657
HY PE+ + TL+NFT++ GLE QLL +VV+ ERPDLE+ K L + ELK +E
Sbjct: 3332 HYTPEISTKLTLINFTLSPSGLEDQLLGQVVAEERPDLEEAKNQLIISNAKMRQELKDIE 3391
Query: 3658 DDLLLRLSAAEGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENERKINEARECYRPVAA 3717
D +L RLS++EG+ +DD +L++ LEA+K AEI+ KV A++ E+ I+ R Y PVA
Sbjct: 3392 DQILYRLSSSEGNPVDDMELIKVLEASKMKAAEIQAKVRIAEQTEKDIDLTRMEYIPVAI 3451
Query: 3718 RASLLYFVINDLQKINPLYQFSLKAFNVLFHRAIEQADKVEDMQGRISILMESITHAVFL 3777
R +L+F ++DL ++P+YQ+SL+ F +F I +++ ++++ RIS + +T++++
Sbjct: 3452 RTQILFFCVSDLANVDPMYQYSLEWFLNIFLSGIANSERADNLKKRISNINRYLTYSLYS 3511
Query: 3778 YTSQALFEKDKLTFLSQMAFQILLRKKEIDPLELDFLL---RFTVEHTHLSPVDFLTSQS 3834
++LFEK KL F + +I++ + +I+ E +LL ++ + +P D+L+ ++
Sbjct: 3512 NVCRSLFEKHKLMFAFLLCVRIMMNEGKINQSEWRYLLSGGSISIMTENPAP-DWLSDRA 3570
Query: 3835 WSAIKAIAVMEEFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKK-KSLIQKLILLRA 3893
W I A++ + F D ++R +S P +E LP W + QKL++LR
Sbjct: 3571 WRDILALSNLPTFSSFSSDFVKHLSEFRVIFDSLEPHREPLPGIWDQYLDQFQKLLVLRC 3630
Query: 3894 MRPDRMTYALRNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEIL 3953
+R D++T A+++FV L +++E +L F++S+ TP+ F+LSPG D DL
Sbjct: 3631 LRGDKVTNAMQDFVATNLEPRFIEPQTANLSVVFKDSNSTTPLIFVLSPGTDPAADLYKF 3690
Query: 3954 GKRLGFTIDSGKFHNVSLGQGQETVAEVALEKASKGGHWVILQNVHLVAKWLGTLEKLLE 4013
+ + F S K +SLGQGQ AE + + + G WV QN HL W+ LE+L+E
Sbjct: 3691 AEEMKF---SKKLSAISLGQGQGPRAEAMMRSSIERGKWVFFQNCHLAPSWMPALERLIE 3747
Query: 4014 RFSQGS-HRDYRVFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHAALYNFDQ 4072
+ HRD+R++++ S P+ + P +L+N K+T EPP G+ ANL + + +
Sbjct: 3748 HINPDKVHRDFRLWLT--SLPS---NKFPVSILQNGSKMTIEPPRGVRANLLKSYSSLGE 3802
Query: 4073 DTLEICSKEQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICASVLYNYLE 4132
D L C K EFKS+L SLC FH R +FGP G++ Y F GDL IC S L +L+
Sbjct: 3803 DFLNSCHKVMEFKSLLLSLCLFHGNALERRKFGPLGFNIPYEFTDGDLRICISQLKMFLD 3862
Query: 4133 ANSKVPWEDLRYLFGEIMYGGHITDDWDRKLCRVYLEEFMNPS-LTEDELMLAPGF--AA 4189
+P++ L+Y GEI YGG +TDDWDR+ LE+F NP L+ + A G
Sbjct: 3863 EYDDIPYKVLKYTAGEINYGGRVTDDWDRRCIMNILEDFYNPDVLSPEHSYSASGIYHQI 3922
Query: 4190 PPYLDYAGYHQYIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALSGDE 4249
PP D GY YI+ + + P ++GLH NA I F + L T++++QP+++ +G
Sbjct: 3923 PPTYDLHGYLSYIKSLPLNDMPEIFGLHDNANITFAQNETFALLGTIIQLQPKSSSAG-- 3980
Query: 4250 LGQSTEEKVKNVLDDILEKLPEEFNMAEIMQKNS--NRSPYVLVCFQECERMNILIREIR 4307
Q EE V++V +IL K+PE N+ +M K V QE R N L++ I
Sbjct: 3981 -SQGREEIVEDVTQNILLKVPEPINLQWVMAKYPVLYEESMNTVLVQEVIRYNRLLQVIT 4039
Query: 4308 ISLEQLDLSLKGELALSPAVEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRE 4367
+L+ L +LKG + +S +E +L +TVP+ WS AYPS L+ W DLL R
Sbjct: 4040 QTLQDLLKALKGLVVMSSQLELMAASLYNNTVPELWSAKAYPSLKPLSSWVMDLLQRLDF 4099
Query: 4368 LDTWTQDLTLPAVVWLSGFFNPQSFLTAIMQTMARKNEWPLDKTRLTADVTKKTKEDYGH 4427
L W QD +PAV W+SGFF PQ+FLT +Q ARK +D V + +
Sbjct: 4100 LQAWIQD-GIPAVFWISGFFFPQAFLTGTLQNFARKFVISIDTISFDFKVMFEAPSELTQ 4158
Query: 4428 PPREGAYLHGLFMEGARWDTQAGTIVEARLKELACPMPVIFAKATPVDRQETKQTYECPV 4487
P+ G Y+HGLF+EGARWD +A + E++ KEL M VI+ TP + + + Y CP+
Sbjct: 4159 RPQVGCYIHGLFLEGARWDPEAFQLAESQPKELYTEMAVIWLLPTPNRKAQDQDFYLCPI 4218
Query: 4488 YRTKLR---------GPSYIWTFRLKSEEKTAKWVLAGVALL 4520
Y+T R +Y+ + + + W+ GVAL+
Sbjct: 4219 YKTLTRAGTLSTTGHSTNYVIAVEIPTHQPQRHWIKRGVALI 4260
>gi|194353966 dynein, axonemal, heavy polypeptide 6 [Homo sapiens]
Length = 4158
Score = 1993 bits (5163), Expect = 0.0
Identities = 1179/3360 (35%), Positives = 1844/3360 (54%), Gaps = 168/3360 (5%)
Query: 1282 LDKANEELEALEEEMLQMQESTRLFEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSID 1341
L+ L L++ Q + + F+V + +++ +++ E+KL + LWD +
Sbjct: 845 LNNLQSVLADLQKRAFQYKSYQKNFKVEVSKFEALEEVSAELKLKQLLWDSFSEWDKLQQ 904
Query: 1342 NWTKTQWRQIHVEQMDVELRRFAKASSITEIWSLNKEVRVWDAYTGLEGTVKDMTASLRA 1401
W K+++ + E ++ ++ ++AK + L K + L+ V+ M L
Sbjct: 905 EWLKSKFDCLDPEVLNGQVSKYAKF-----VTQLEKGLPPNSVVPQLKYKVEKMKEKLPV 959
Query: 1402 ITELQSPALRDRHWHQLMKAIGVKFLINEAT-TLADLLALRLHRVEDDVRRIVDKAVKEL 1460
I +L++P L+ RHW + + + + E TL L L + +++ I +A E
Sbjct: 960 IIDLRNPTLKARHWAAIEQTVDATLVDAEIPLTLERLSQLHVFDFGQEIQDISGQASGEA 1019
Query: 1461 GTEKVITEISQTWATMKFSYEVHYRT-GIPLLKSDEQLFETLEHNQVQLQTLLQSKYVEY 1519
E ++ ++ +W T +F H + + +L + + L+ + + + TL S+Y+
Sbjct: 1020 ALEAILKKVEDSWKTTEFVILPHRDSKDVFILGGTDDIQVLLDDSTINVATLASSRYLGP 1079
Query: 1520 FIEQVLSWQNKLNIADLVIFTWMEVQRTWSHLESIFVCSEDIRIQLVKDARRFDGVDAEF 1579
+V WQ +L + + + W+ QR W +LESIF + DI+ QL +A+ F VD +
Sbjct: 1080 LKTRVDEWQKQLALFNQTLEEWLTCQRNWLYLESIFN-APDIQRQLPAEAKMFLQVDKSW 1138
Query: 1580 KELMFKTAKVENVLEATCRPNLYEKLKDLQSRLSLCEKALAEYLETKRIAFPRFYFVSSA 1639
KE+M K ++ N L A +P L E ++ + L +K L YLE+KR+ FPRFYF+S+
Sbjct: 1139 KEIMRKVNRLPNALRAATQPGLLETFQNNNALLDQIQKCLEAYLESKRVIFPRFYFLSND 1198
Query: 1640 DLLDILSKGAQPKQVTCHLAKLFDSIADLQFE--------------DNQDVSAHRAVGMY 1685
+LL+IL++ P+ V HL K FDSI+ L+F + + V + + M
Sbjct: 1199 ELLEILAQTRNPQAVQPHLRKCFDSISKLEFALMPPAEGKIPGIDGEPEKVYTNDILAML 1258
Query: 1686 SKEKEYVPFQAECECVGHVETWLLQLEQTMQETVRHSITEAIVAYEEKPRELWIF-DFPA 1744
S E E V + G+VE WL ++E+ M ++R AI Y+ K R W+ P+
Sbjct: 1259 SPEGERVSLGKGLKARGNVEEWLGKVEEAMFTSLRRLCKAAIADYQGKLRTDWVVAGHPS 1318
Query: 1745 QVALTSSQIWWTTDVGIAFSRLEEGYETALKDFHKKQISQLNTLITLLLGELPPGDRQKI 1804
QV LT SQI W D+ + ALK+F K +LN L ++ G LP R +
Sbjct: 1319 QVILTVSQIMWCRDLTECLETEHSNHIQALKNFEKVNFERLNALAAIVQGSLPKLHRNIL 1378
Query: 1805 MTICTIDVHARDVVAKLISQKQVVVSPQAFTWLSQLRHRWEDTQKHCFVNICDAQFQYFY 1864
+ TIDVHARD+V +L+ K V + ++F W QLR+ W+ +C + +Q+ Y Y
Sbjct: 1379 TALITIDVHARDIVTELVQSK--VETVESFDWQRQLRYYWDIDLDNCVARMALSQYTYGY 1436
Query: 1865 EYLGNSPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVF 1924
EYLG PRLVITPLTDRCY+ L +L L + GAPAGPAGTGKTETTKDL +AL + VF
Sbjct: 1437 EYLGACPRLVITPLTDRCYLCLMGALQLDLGGAPAGPAGTGKTETTKDLAKALAIQCVVF 1496
Query: 1925 NCSEQMDYKSIGNIYKGLVQTGAWGCFDEFNRISVEVLSVVAVQVKMIHDAIRNRKKRFV 1984
NCS+ +DYK +G + GL Q+GAW CFDEFNRI +EVLSV+A Q+ I +A + RF+
Sbjct: 1497 NCSDGLDYKMMGRFFSGLAQSGAWCCFDEFNRIDIEVLSVIAQQLITIRNAKAAKLSRFM 1556
Query: 1985 FLGEAITLKPSVGIFITMNPGYAGRTELPENLKALFRPCAMVAPDIELICEILLVAEGFV 2044
F G I L + FITMNPGYAGRTELP+NLKALFRP AM+ P+ LI E++L +EGF
Sbjct: 1557 FEGREIKLVMTCAAFITMNPGYAGRTELPDNLKALFRPFAMMVPNYALIAEVILYSEGFE 1616
Query: 2045 DARALARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDKNRPEDQVLMRAL 2104
++ LARK +Y LC E LS+QDHYD+G+RA+KSVLV+AGSLKR + + ED VL+RAL
Sbjct: 1617 SSKILARKMTQMYKLCSEQLSQQDHYDFGMRAVKSVLVMAGSLKRENPDLNEDVVLIRAL 1676
Query: 2105 RDFNMPKIVTDDIPVFLGLVGDLFPALDVPRRRKLHFEQMVRQSTLELRLQPEESFILKV 2164
+D N+PK +TDD +F G++ DLFP + +P + + LQPE + KV
Sbjct: 1677 QDSNLPKFLTDDALLFSGIISDLFPGVQIPEHDYGILQSTIVDVMNRQNLQPEMCMVRKV 1736
Query: 2165 VQLEELLAVRHSVFVVGNAGTGKSKILRTLNRTYVNMKQKPVWND---------LNPKAV 2215
+Q E + VRH V +VG G GK+ + R L T N+++ + N LNPK++
Sbjct: 1737 IQFYETMLVRHGVMLVGPTGGGKTTVYRILAETLGNLQKLGIENSFYQAVKTYVLNPKSI 1796
Query: 2216 TTDELFGFIHHATREWKDGKIVYSYFIGLFSSILREQANLKHDGPKWIVLDGDIDPMWIE 2275
T EL+G +++ T EWKDG + S +R N + KWI+ DG +D +WIE
Sbjct: 1797 TMGELYGEVNNLTLEWKDGLMALS---------VRAAVNDTSEDHKWIISDGPVDALWIE 1847
Query: 2276 SLNTVMDDNKVLTLASNERIALTPFMRLLFEIHHLRSATPATVSRAGILYVNPQDLGWNP 2335
++NTV+DDNK+L LA++ERI LTP + +LFE+ LR A+PATVSR G+++V+P++L W P
Sbjct: 1848 NMNTVLDDNKMLCLANSERIKLTPQIHMLFEVQDLRVASPATVSRCGMVFVDPEELKWMP 1907
Query: 2336 YVASW---IDRRRHQSEKANLTILFDKYVPACLDKLRTSFKTITSIPESSLVQTLCVLLE 2392
YV +W I ++ + + + LF +YV L + + S V TLC LLE
Sbjct: 1908 YVKTWMKGISKKLTEETQEYILNLFQRYVDEGLHFINKKCSQAIPQVDISKVTTLCCLLE 1967
Query: 2393 CLLTPE---NVPSDSPK--EVYEVYFVFACIWAFGGTLLQDQISDYQADFSRWWQKEMKA 2447
L+ + N+ + K + FVF +W+ GG L ++ + F R +
Sbjct: 1968 SLILGKDGVNLAMEQTKLNTILCQTFVFCYLWSLGGNLTENYYDSFDT-FIRTQFDDNPD 2026
Query: 2448 VKFPSQGTIFDYYVDHKTKKLLPWADKIAQFTMDPDVPLQTVLVHTTETARLRYFMELLL 2507
+ P+ G ++ ++D TK+L PW I F + DVP +LV TT+T R Y ME LL
Sbjct: 2027 ARLPNSGDLWSIHMDFDTKRLDPWERIIPTFKYNRDVPFFEMLVPTTDTVRYGYLMEKLL 2086
Query: 2508 EKGKPLMLVGNAGVGKTVFVGDTLASLSED--YIVSRVPFNYYTTSTALQKILEKPLEKK 2565
++ G GVGK+V L + E Y+ + F+ T+S Q+I+E LE+K
Sbjct: 2087 AVKHSVLFTGITGVGKSVIAKGLLNKIQESAGYVPVYLNFSAQTSSARTQEIIESKLERK 2146
Query: 2566 AGHNYGPGGNKKLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYDRQKVMLKEIHNC 2625
+ G GNK+++ F+DD+NMP +D YG+ P L+RQ+ D+G +YDR K+ KEI +
Sbjct: 2147 RKNILGAPGNKRIVIFVDDLNMPRLDRYGSQPPIELLRQYQDFGGFYDRNKLFWKEIQDV 2206
Query: 2626 QYV-ACMNPMVGSFTINPRLQRHFTVFAFNFPSLDALNTIYGQIFSFHFQQQAFAPSILR 2684
+ AC P G + PR RHF++ PS +L I+ I + F P++ +
Sbjct: 2207 TIISACAPPGGGRNPVTPRFIRHFSMLCLPMPSEHSLKQIFQAILNGFLSD--FPPAVKQ 2264
Query: 2685 SGPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFASPECLKGPLDLIHL 2744
+ ++++A++ + M + LPT K HY+FNLRDLS QGIL P ++ + + L
Sbjct: 2265 TASSIVEASVEIYNKMSVDLLPTPAKSHYVFNLRDLSKCVQGILQCDPGTIREEIQIFRL 2324
Query: 2745 WLHESARVYGDKLIDKKDCDLFQRRMLETAYKYFE-GIDSHMLLQQPLIYCHFADRGKDP 2803
+ HE RV+ D+LI+ +D F + E A K+F ID L +P+I+ F G D
Sbjct: 2325 FCHECQRVFHDRLINNEDKHYFHVILTEMANKHFGIAIDLEYFLNKPIIFGDFIKFGADK 2384
Query: 2804 H---YMPVKDWEVLKTILTETLDNYNELN-AAMHLVLFEDAMQHVCRISRILRTPQGCAL 2859
Y + D E +L + LD+YN N + LV F+DA++HV RI+R++R +G AL
Sbjct: 2385 ADRIYDDMPDIEKTANVLQDYLDDYNLTNPKEVKLVFFQDAIEHVSRIARMIRQERGNAL 2444
Query: 2860 LVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYGIQELRVDLANLYIRTGAKNMPTVFLL 2919
LVGVGG+GKQSL+RLAA++ G + QI L+ GY DL LY G ++ VFL
Sbjct: 2445 LVGVGGTGKQSLTRLAAHICGYKCLQIELSRGYNYDSFHEDLRKLYKMAGVEDKNMVFLF 2504
Query: 2920 TDAQVLDESFLVLINDLLASGEIPDLFSDEDVDKIISGIHNEVHALGMVD-SRENCWKFF 2978
TD Q++ E FL IN++L SGE+P+LF ++++++++ +G+ + +R+ +++F
Sbjct: 2505 TDTQIVVEEFLEDINNILNSGEVPNLFEKDELEQVLAATRPRAKEVGISEGNRDEVFQYF 2564
Query: 2979 MARVRLQLKIILCFSPVGRTLRVRARKFPAIVNCTAIDWFHAWPQEALVSVSRRFIEETK 3038
+++VR +L I+LC SPVG R R R FP++VNC IDWF WP+EAL+SVS+ F +
Sbjct: 2565 ISKVRQKLHIVLCMSPVGEAFRSRCRMFPSLVNCCTIDWFVQWPREALLSVSKTFFSQVD 2624
Query: 3039 GIEPVHKDSISLFMAHVHTTVNEMSTRYYQNERRHNYTTPKSFLEQISLFKNLLKKKQNE 3098
K+ + L +VH +V+ M+ RYY RR YTTP S+LE I+L+ ++L +K+ +
Sbjct: 2625 AGNEELKEKLPLMCVNVHLSVSSMAERYYNELRRRYYTTPTSYLELINLYLSMLSEKRKQ 2684
Query: 3099 VSEKKERLVNGIQKLKTTASQVGDLKARLASQEAELQLRNHDAEALITKIGLQTEKVSRE 3158
+ ++R+ NG+ KL T V +K L++ E L ++ D EAL+ K+ + E +
Sbjct: 2685 IISARDRVKNGLTKLLETNILVDKMKLDLSALEPVLLAKSEDVEALMEKLAVDQESADQV 2744
Query: 3159 KTIADAEE--RKVTAIQTEVFQKQRECEADLLKAEPALVAATAALNTLNRVNLSELKAFP 3216
+ +E KV A +T+ + + DL +A PAL AA AL++L++ ++SE++ F
Sbjct: 2745 RNTVQEDEATAKVKAEETQAIAD--DAQRDLDEALPALDAANKALDSLDKADISEIRVFT 2802
Query: 3217 NPPIAVTNVTAAVMVLLAPRGRVPKDRSWKAAKVFMGKVDDFLQALINYDKEHIPENCLK 3276
PP V V A+ +LL + W +AK +G +FL+ L+ YDKE+I L
Sbjct: 2803 KPPDLVMTVMEAISILLNAK------PDWPSAKQLLGD-SNFLKRLLEYDKENIKPQILA 2855
Query: 3277 VVNEHYLKDPEFNPNLIRTKSFAAAGLCAWVINIIKFYEVYCDVEPKRQALAQANLELAA 3336
+ + Y+ +P+F P + S A +C WV + + V VEPKRQ L A EL
Sbjct: 2856 KL-QKYINNPDFVPEKVEKVSKACKSMCMWVRAMDLYSRVVKVVEPKRQKLRAAQAELDI 2914
Query: 3337 ATEKLEAIRKKLVDLDRNLSRLTASFEKATAEKVRCQEEVNQTNKTIKLANRLVKELEAK 3396
L + L ++ + L ++K EK + + T + A +L LE +
Sbjct: 2915 TMATLREKQALLRQVEDQIQALQDEYDKGVNEKESLAKTMALTKARLVRAGKLTAALEDE 2974
Query: 3397 KIRWGQSIKSFEAQEKTLCGDVLLTAAFVSYVGPFTRQYRQELVHCKWVPFLQQKVSIPL 3456
++RW +SI+ FE + + G+V + AA V+Y G FT QYRQ L+ C W+ Q + IP+
Sbjct: 2975 QVRWEESIQKFEEEISNITGNVFIAAACVAYYGAFTAQYRQSLIEC-WIQDC-QSLEIPI 3032
Query: 3457 TEGLDLISMLTDDATIAAWNNEGLPSDRMSTENAAILTHCERWPLVIDPQQQGIKWIKNK 3516
LI++L D I WN +GLP D +STEN ++T RWPL+IDPQ Q +WI+NK
Sbjct: 3033 DPSFSLINILGDPYEIRQWNTDGLPRDLISTENGILVTQGRRWPLMIDPQDQANRWIRNK 3092
Query: 3517 YGMD-LKVTHLGQKGFLNAIETALAFGDVILIENLEETIDPVLDPLLGRNTIKKG--KYI 3573
LK+ L FL +E ++ G +L+E L+ET+DP L+P+L + G I
Sbjct: 3093 ESKSGLKIIKLTDSNFLRILENSIRLGLPVLLEELKETLDPALEPILLKQIFISGGRLLI 3152
Query: 3574 RIGDKECEFNKNFRLILHTKLANPHYKPELQAQTTLLNFTVTEDGLEAQLLAEVVSIERP 3633
R+GD + +++KNFR + TK+ NPHY PE+ + T++NFTVT+ GLE QLL++VV +E+P
Sbjct: 3153 RLGDSDIDYDKNFRFYMTTKMPNPHYLPEVCIKVTIINFTVTKSGLEDQLLSDVVRLEKP 3212
Query: 3634 DLEKLKLVLTKHQNDFKIELKYLEDDLLLRLSAAEGSFLDDTKLVERLEATKTTVAEIEH 3693
LE+ ++ L N K +LK +E+ +L L +EG+ LD+ +L++ L+ +K T I+
Sbjct: 3213 RLEEQRIKLIVRINTDKNQLKTIEEKILRMLFTSEGNILDNEELIDTLQDSKITSGAIKT 3272
Query: 3694 KVIEAKENERKINEARECYRPVAARASLLYFVINDLQKINPLYQFSLKAFNVLFHRAIEQ 3753
++ EA+ E+ IN ARE YRPVA + S++YFVI L +I+P+YQ+SLK F LF+ IE
Sbjct: 3273 RLEEAESTEQMINVAREKYRPVATQGSVMYFVIASLSEIDPMYQYSLKYFKQLFNTTIET 3332
Query: 3754 ADKVEDMQGRISILMESITHAVFLYTSQALFEKDKLTFLSQMAFQILLRKKEIDPLELDF 3813
+ K E++Q R+ +L+E ++ S+ LFE+ KL + + +++ ++ + E +F
Sbjct: 3333 SVKTENLQQRLDVLLEQTLLTAYVNVSRGLFEQHKLIYSFMLCVEMMRQQGTLSDAEWNF 3392
Query: 3814 LLRFTV----EHTHLSPVDFLTSQSWSAIKAIAVMEE----FRGIDRDV--------EGS 3857
LR + E +L + +W A +EE F G+ +++ GS
Sbjct: 3393 FLRGSAGLEKERPPKPEAPWLPTATWF---ACCDLEESFPVFHGLTQNILSHPISIRLGS 3449
Query: 3858 AKQW---RKWV---------ESECPEKEKLPQE-WKK-KSLIQKLILLRAMRPDRMTYAL 3903
+ + +KW + EKE Q+ W S KLIL++ + +++ +AL
Sbjct: 3450 FETYINPQKWEGYSKMKHEDKHMRQEKEAAHQDPWSAGLSSFHKLILIKCCKEEKVVFAL 3509
Query: 3904 RNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEILGKRLGFTIDS 3963
+FV E LG +++E +DL +++ S TP+ FILS G D + + + G+ S
Sbjct: 3510 TDFVIENLGKQFIETPPVDLPTLYQDMSCNTPLVFILSTGSDPMGAFQRFARESGY---S 3566
Query: 3964 GKFHNVSLGQGQETVAEVALEKASKGGHWVILQNVHLVAKWLGTLEKLLERFSQGSHR-- 4021
+ ++SLGQGQ +AE ++ A K G+WV LQN HL W+ +E+L++ F+
Sbjct: 3567 ERVQSISLGQGQGPIAEKMVKDAMKSGNWVFLQNCHLAVSWMLAMEELIKTFTDPDSAIK 3626
Query: 4022 -DYRVFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHAALYNFDQDTLEICSK 4080
+R+F+S+ + T P +L+NS+K+TNEPP G+ AN+ A E
Sbjct: 3627 DTFRLFLSSMPSNT-----FPVTVLQNSVKVTNEPPKGLRANIRRAFTEMTPSFFEENIL 3681
Query: 4081 EQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICASVLYNYLEANSKVPWE 4140
++++ I+F +C+FHA + R +FGP GW+ Y FN D CA + K+PW+
Sbjct: 3682 GKKWRQIIFGICFFHAIIQERKKFGPLGWNICYEFNDSDRE-CALLNLKLYCKEGKIPWD 3740
Query: 4141 DLRYLFGEIMYGGHITDDWDRKLCRVYLEEFMNPSLTEDELMLAPG--FAAPPYLDYAGY 4198
L Y+ GEI YGG +TD WD++ R L+ F +P E++ + + AP +
Sbjct: 3741 ALIYITGEITYGGRVTDSWDQRCLRTILKRFFSPETLEEDYKYSESGIYFAPMADSLQEF 3800
Query: 4199 HQYIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALSGDELGQSTEEKV 4258
YIE + + P ++G+H NA + F ++TL T+LE+QPR++ G+ G+S +E V
Sbjct: 3801 KDYIENLPLIDDPEIFGMHENANLVFQYKETSTLINTILEVQPRSSTGGE--GKSNDEIV 3858
Query: 4259 KNVLDDILEKLPEEFNMAE------IMQKNSNRSPYVLVCFQECERMNILIREIRISLEQ 4312
+ ++ + ++PE+ M + + V QE +R N L++ I SLE
Sbjct: 3859 QELVASVQTRVPEKLEMEGASESLFVKDLQGRLNSLTTVLGQEVDRFNNLLKLIHTSLET 3918
Query: 4313 LDLSLKGELALSPAVEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRELDTWT 4372
L+ ++ G + +S +E + + VP WS AYPS L W DL+LR +D W
Sbjct: 3919 LNKAIAGFVVMSEEMEKVYNSFLNNQVPALWSNTAYPSLKPLGSWVKDLILRTSFVDLWL 3978
Query: 4373 QDLTLPAVVWLSGFFNPQSFLTAIMQTMARKNEWPLDKTRLTADVTKKTKE--------- 4423
+ P W+SGFF PQ FLT +Q ARK P+D+ V ++
Sbjct: 3979 K-RGQPKSYWISGFFFPQGFLTGTLQNHARKYNLPIDELSFKYSVIPTYRDQAAVIEAAK 4037
Query: 4424 --DYGH---------PPREGAYLHGLFMEGARWDTQAGTIVEARLKELACPMPVIFAKAT 4472
+G P +G +HG+FM+ +RWD + I +A ++ +PV+ +
Sbjct: 4038 TVQFGQELPMDMELPSPEDGVLVHGMFMDASRWDDKEMVIEDALPGQMNPVLPVVHFE-- 4095
Query: 4473 PVDRQETKQT-YECPVYRTKLR---------GPSYIWTFRLKSEEKTAKWVLAGVALLLE 4522
P + T Y CP+Y+T R +++ T L S+ W+ G ALL +
Sbjct: 4096 PQQNYKPSPTLYHCPLYKTGARAGTLSTTGHSTNFVVTVLLPSKRSKDYWIAKGSALLCQ 4155
>gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens]
Length = 4024
Score = 1909 bits (4946), Expect = 0.0
Identities = 1151/3346 (34%), Positives = 1828/3346 (54%), Gaps = 159/3346 (4%)
Query: 1286 NEELEALEEEMLQMQESTRLFEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTK 1345
N +L+ +++ Q F Y Q K+ + + L++ + + WT+
Sbjct: 726 NGKLDLAADKIEQFNAEEEAFGWLPSVYPQRKKIQDGLNPYLRLYETAVEFSSNYRAWTE 785
Query: 1346 TQWRQIHVEQMDVELRRFAKASSITE--------IWSLNKEVRVWDAYTGLEGTVKDMTA 1397
+ +++ +Q++ ++ + + E ++ K+VR V+D
Sbjct: 786 GPYHKVNPDQVEADIGNYWRGLYKLEKTFHDSPYALAMTKKVR---------SKVEDFKQ 836
Query: 1398 SLRAITELQSPALRDRHWHQLMKAIGVKFLINEATTLADLLALRLHRVEDDVRRIVDKAV 1457
+ I + +P LR RHW + +G ++ +T++ L + L D I + A
Sbjct: 837 HIPLIQVICNPGLRPRHWEAMSAIVGYPLQPSDDSTVSSFLDMNLEPYIDRFEGISEAAS 896
Query: 1458 KELGTEKVITEISQTWATMKFSYEVHYRTGIPLLKSDEQLFETLEHNQVQLQTLLQSKYV 1517
KE EK + ++ W ++F + TG +L S +++ L+ + ++ QT+ S ++
Sbjct: 897 KEYSLEKAMEKMITEWDAVEFVIHSYRETGTFILASVDEIQMLLDDHIIKTQTMRGSPFI 956
Query: 1518 EYFIEQVLSWQNKLNIADLVIFTWMEVQRTWSHLESIFVCSEDIRIQLVKDARRFDGVDA 1577
+ + +Q+ W+ KL + ++ W++VQ TW +LE IF S DI Q+ ++ RRF VD
Sbjct: 957 KPYEKQMREWEGKLLLLQEILDEWLKVQATWLYLEPIF-SSPDIMSQMPEEGRRFTAVDK 1015
Query: 1578 EFKELMFKTAKVENVLEATCRPNLYEKLKDLQSRLSLCEKALAEYLETKRIAFPRFYFVS 1637
++++M + ++VL + E+LK L L K L EYLE KR+ FPRF+F+S
Sbjct: 1016 TWRDIMRSVMQDKHVLTVVTIDRMLERLKKSNELLELILKGLNEYLEKKRLFFPRFFFLS 1075
Query: 1638 SADLLDILSKGAQPKQVTCHLAKLFDSIADLQFEDNQDVSAHRAVGMYSKEKEYVPFQAE 1697
+ +LL+ILS+ P +V HL K F+ IA ++F + D++ ++ + E + +
Sbjct: 1076 NDELLEILSETKDPTRVQPHLKKCFEGIAKVEFTETLDITHMKS--SEGEVVELIEIIST 1133
Query: 1698 CECVGHVETWLLQLEQTMQETVRHSITEAIVAYEEKPRELWIFDFPAQVALTSSQIWWTT 1757
+ G VE WL++LE+ M ++ +A AY + R W+ D+P Q L SQI+WT
Sbjct: 1134 AKARGQVEKWLVELERVMINSIHKVTGDATFAYTKYERINWVRDWPGQTVLCVSQIFWTK 1193
Query: 1758 DVGIAFSRLEEGYETALKDFHKKQISQLNTLITLLLGELPPGDRQKIMTICTIDVHARDV 1817
+V A + E LK ++ Q++ ++TL+ G+L +R + + +DVHARDV
Sbjct: 1194 EVQTAIPMGIKALEQYLKTCNR----QIDDIVTLVRGKLSMQNRVTLGALVVLDVHARDV 1249
Query: 1818 VAKLISQKQVVVSPQAFTWLSQLRHRWEDTQKHCFVNICDAQFQYFYEYLGNSPRLVITP 1877
++ L+ K+ + F WLSQLR+ W++ H + +A +Y YEYLGNSPRLVITP
Sbjct: 1250 LSSLV--KKNISDDSDFEWLSQLRYYWQEN--HLETKMINAGLRYGYEYLGNSPRLVITP 1305
Query: 1878 LTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDYKSIGN 1937
LTDRCY TL +LHL + GAP GPAGTGKTETTKDL +A+ VFNCS+ +DY ++G
Sbjct: 1306 LTDRCYRTLFGALHLHLGGAPEGPAGTGKTETTKDLAKAVAKQCVVFNCSDGLDYLALGK 1365
Query: 1938 IYKGLVQTGAWGCFDEFNRISVEVLSVVAVQVKMIHDAIRNRKKRFVFLGEAITLKPSVG 1997
+KGL+ GAW CFDEFNRI +EVLSVVA Q+ I I +F G + L P+
Sbjct: 1366 FFKGLLSCGAWACFDEFNRIDLEVLSVVAQQILTIQRGINAGADILMFEGTELKLDPTCA 1425
Query: 1998 IFITMNPGYAGRTELPENLKALFRPCAMVAPDIELICEILLVAEGFVDARALARKFITLY 2057
+FITMNPGYAGR+ELP+NLKALFR AM+ PD +I EI+L + GFV AR L+ K + Y
Sbjct: 1426 VFITMNPGYAGRSELPDNLKALFRTVAMMVPDYAMIAEIVLYSCGFVTARPLSVKIVATY 1485
Query: 2058 TLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDKNRPEDQVLMRALRDFNMPKIVTDDI 2117
LC E LS Q HYD+G+RA+KSVL AG+LK N E+ +L+R++ D N+PK ++ D+
Sbjct: 1486 RLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPNENEEILLLRSIIDVNLPKFLSHDL 1545
Query: 2118 PVFLGLVGDLFPALDVPRRRKLHFEQMVRQSTLELRLQPEESFILKVVQLEELLAVRHSV 2177
P+F G+ DLFP + +P+ ++ + + LQ F K++Q+ E++ VRH
Sbjct: 1546 PLFEGITSDLFPGVKLPKPDYNDLLAAIKDNCASMNLQMTAFFSEKILQVYEMMIVRHGF 1605
Query: 2178 FVVGNAGTGKSKILRTLNRTYVNMKQKPVWND-------LNPKAVTTDELFGFIHHATRE 2230
+VG GK+ R L ++ +K + + LNPK+VT +L+G + E
Sbjct: 1606 MIVGEPFGGKTSAYRVLAGALNDICEKGLMEENKVQITVLNPKSVTMGQLYGQFDSVSHE 1665
Query: 2231 WKDGKIVYSYFIGLFSSILREQANLKHDGPKWIVLDGDIDPMWIESLNTVMDDNKVLTLA 2290
W DG + S F SS+ ++ KW++ DG +D +WIE++NTV+DDNK L L
Sbjct: 1666 WSDGVLAVS-FRAFASSVTPDR--------KWLIFDGPVDAVWIENMNTVLDDNKKLCLM 1716
Query: 2291 SNERIALTPFMRLLFEIHHLRSATPATVSRAGILYVNPQDLGWNPYVASWID---RRRHQ 2347
S E I ++P M L+FE L A+PATVSR G++Y+ P LGW P + SW++
Sbjct: 1717 SGEIIQMSPQMNLIFEPMDLEVASPATVSRCGMIYMEPHMLGWRPLMLSWVNLLPASVSV 1776
Query: 2348 SEKANLTILFDKYVPACLDKLRTSFKTITSIPESSLVQTLCVLLECLL----TPENVPSD 2403
+K + LFD+ VP ++ +R K ++ +++LV++L L++C + +
Sbjct: 1777 IQKEFIMGLFDRMVPVSVEFIRKHTKELSPTSDTNLVRSLMNLIDCFMDDFADEVKLKER 1836
Query: 2404 SPKEVY---EVYFVFACIWAFGGT---------------LLQDQISDYQADF----SRWW 2441
+ +E Y E F+F+ IW+ G + L++ ISD + S
Sbjct: 1837 NDRETYSLLEGIFLFSLIWSVGASCTDDDRLKFNKILRELMESPISDRTRNTFKLQSGTE 1896
Query: 2442 QKEMKA--VKFPSQGTIFDY-YVDHKTKKLLPWADKIAQFTMDP-DVPLQTVLVHTTETA 2497
Q KA V FP +GTI+DY +V K PW K+ + P DV ++V T +T
Sbjct: 1897 QTSSKALTVPFPEKGTIYDYQFVTEGIGKWEPWIKKLKEAPPIPKDVMFNEIIVPTLDTI 1956
Query: 2498 RLRYFMELLLEKGKPLMLVGNAGVGKTVFVGDTLASL--SEDYIVSRVPFNYYTTSTALQ 2555
R MELL KP + VG G GK+V++ + L + E Y + F+ TT+ Q
Sbjct: 1957 RYSALMELLTTHQKPSIFVGPTGTGKSVYITNFLLNQLNKEIYKPLLINFSAQTTAAQTQ 2016
Query: 2556 KILEKPLEKKAGHNYGPGGNKKLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYDRQ 2615
I+ L+K+ +GP K+++ F+DD+NMP ++YG P L+RQ +D+ +WYD +
Sbjct: 2017 NIVMSKLDKRRKGVFGPPLGKRMVVFVDDVNMPAREVYGAQPPIELLRQWLDHWNWYDLK 2076
Query: 2616 KVMLKEIHNCQYVACMNPMVGSFT-INPRLQRHFTVFAFNFPSLDALNTIYGQIFSFHFQ 2674
+ ++ + Q + M P G + PR RHF + N S ++ TI+ +I ++H +
Sbjct: 2077 DCSMIKLVDIQIMCAMGPPGGGRNPVTPRYMRHFNIITINEFSDKSMYTIFSRILTWHLE 2136
Query: 2675 -QQAFAPSILRSGPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFASPE 2733
F L ++ T+ ++ M N LPT K HY+FNLRD S V QG+ + PE
Sbjct: 2137 ICYKFPDEFLDLTTQIVNGTMTLYKEAMKNLLPTPAKSHYLFNLRDFSRVIQGVCLSRPE 2196
Query: 2734 CLKGPLDLIHLWLHESARVYGDKLIDKKD--------CDLFQRRMLETAYKYFEGI--DS 2783
+ + LW+HE RVY D+L+D D ++ + M E ++ F+ + D+
Sbjct: 2197 TTETTEVIKRLWVHEVLRVYYDRLLDNTDRSWLINYIQEILRNYMYEDFHELFQRLDFDN 2256
Query: 2784 HMLLQ----QPLIYCHFAD-RGKDPHYMPVKDWEVLKTILTETLDNYNELN-AAMHLVLF 2837
+++ + L++C F D + +D +Y + D + L+ I+ L+ YN ++ M+LVLF
Sbjct: 2257 DGMVEADDLRSLMFCDFHDPKREDTNYREIADVDNLRMIVEIHLEEYNNISKKPMNLVLF 2316
Query: 2838 EDAMQHVCRISRILRTPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYGIQEL 2897
A++H+ RISRIL+ P+ ALLVGVGGSG+QS++RLAA++ VFQ+ +++GY E
Sbjct: 2317 RFAIEHISRISRILKQPRSHALLVGVGGSGRQSVTRLAAHMADYSVFQVEISKGYDTTEW 2376
Query: 2898 RVDLANLYIRTGAKNMPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDKIISG 2957
DL + + M VFL TD Q+ +ESFL +++LL +GEIP+LF+ ++ +I
Sbjct: 2377 HEDLKVILRKCAEGEMQGVFLFTDTQIKEESFLEDVSNLLNAGEIPNLFALDEKQEICDK 2436
Query: 2958 IHNEVHALGMVDSREN----CWKFFMARVRLQLKIILCFSPVGRTLRVRARKFPAIVNCT 3013
+ + + F+ R QL ++L SP+G R R RKFPA+VNC
Sbjct: 2437 MRQLDRQRDKTKQTDGSPIALFNMFIDHCRSQLHVVLAMSPIGDAFRNRLRKFPALVNCC 2496
Query: 3014 AIDWFHAWPQEALVSVSRRFIEETKGIEPVHKDSISLFMAHVHTTVNEMSTRYYQNERRH 3073
IDWF +WP++AL +V+ RF+EE + E + I + + HT+ ++S ++ +R+
Sbjct: 2497 TIDWFQSWPEDALQAVASRFLEEIEMSEEIRDGCIDMCKS-FHTSTIDLSKSFFVELQRY 2555
Query: 3074 NYTTPKSFLEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLASQEAE 3133
NY TP S+LE IS FK LL+KK++EV + K+R G++KL + +SQV ++ L + +
Sbjct: 2556 NYVTPTSYLELISTFKLLLEKKRSEVMKMKKRYEVGLEKLDSASSQVATMQMELEALHPQ 2615
Query: 3134 LQLRNHDAEALITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQRECEADLLKAEPA 3193
L++ + + + ++ I ++ +V++ + I A+E + EC+ADL A P
Sbjct: 2616 LKVASKEVDEMMIMIEKESVEVAKTEKIVKADETIANEQAMASKAIKDECDADLAGALPI 2675
Query: 3194 LVAATAALNTLNRVNLSELKAFPNPPIAVTNVTAAVMVLLA--------PRGRVPK-DRS 3244
L +A AAL+TL +++ +K+ +PP V V A+ +L P G K +
Sbjct: 2676 LESALAALDTLTAQDITVVKSMKSPPAGVKLVMEAICILKGIKADKIPDPTGSGKKIEDF 2735
Query: 3245 WKAAKVFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLKDPEFNPNLIRTKSFAAAGLC 3304
W AK +G + FLQ+L YDK++IP + ++ ++Y+ +P+F P IR S AA GLC
Sbjct: 2736 WGPAKRLLGDM-RFLQSLHEYDKDNIPPAYMNIIRKNYIPNPDFVPEKIRNASTAAEGLC 2794
Query: 3305 AWVINIIKFYEVYCDVEPKRQALAQANLELAAATEKLEAIRKKLVDLDRNLSRLTASFEK 3364
WVI + + +V V PK+ LA A EL A + L + L ++ L+RL + E
Sbjct: 2795 KWVIAMDSYDKVAKIVAPKKIKLAAAEGELKIAMDGLRKKQAALKEVQDKLARLQDTLEL 2854
Query: 3365 ATAEKVRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLLTAAF 3424
+K + +V+ +K ++ A +L+ L +K RW + L GD+L+++
Sbjct: 2855 NKQKKADLENQVDLCSKKLERAEQLIGGLGGEKTRWSHTALELGQLYINLTGDILISSGV 2914
Query: 3425 VSYVGPFTRQYRQELVHCKWVPFLQQKVSIPLTEGLDLISMLTDDATIAAWNNEGLPSDR 3484
V+Y+G FT YRQ +W + + IP ++ L+ L + TI WN GLPSD
Sbjct: 2915 VAYLGAFTSTYRQNQTK-EWTTLCKGR-DIPCSDDCSLMGTLGEAVTIRTWNIAGLPSDS 2972
Query: 3485 MSTENAAILTHCERWPLVIDPQQQGIKWIKN-KYGMDLKVTHLGQKGFLNAIETALAFGD 3543
S +N I+ + RWPL+IDPQ Q KWIKN + L V L + ++ +E + FG
Sbjct: 2973 FSIDNGIIIMNARRWPLMIDPQSQANKWIKNMEKANSLYVIKLSEPDYVRTLENCIQFGT 3032
Query: 3544 VILIENLEETIDPVLDPLLGRNTIKKG--KYIRIGDKECEFNKNFRLILHTKLANPHYKP 3601
+L+EN+ E +DP+L+PLL + T K+G IR+GD E+ +FR + TKL NPHY P
Sbjct: 3033 PVLLENVGEELDPILEPLLLKQTFKQGGSTCIRLGDSTIEYAPDFRFYITTKLRNPHYLP 3092
Query: 3602 ELQAQTTLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLEDDLL 3661
E + TLLNF +T +G++ QLL VV+ ERPDLE+ K L + K +LK +ED +L
Sbjct: 3093 ETSVKVTLLNFMITPEGMQDQLLGIVVAQERPDLEEEKQALILQGAENKRQLKEIEDKIL 3152
Query: 3662 LRLSAAEGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENERKINEARECYRPVAARASL 3721
LS++EG+ L+D ++ L ++K EI K A+E E+KI+ R YRP+A +S+
Sbjct: 3153 EVLSSSEGNILEDETAIKILSSSKALANEISQKQEVAEETEKKIDTTRMGYRPIAIHSSI 3212
Query: 3722 LYFVINDLQKINPLYQFSLKAFNVLFHRAIEQADKVEDMQGRISILMESITHAVFLYTSQ 3781
L+F + DL I P+YQ+SL F LF +IE ++K E + R+ IL + T+++++ +
Sbjct: 3213 LFFSLADLANIEPMYQYSLTWFINLFILSIENSEKSEILAKRLQILKDHFTYSLYVNVCR 3272
Query: 3782 ALFEKDKLTFLSQMAFQILLRKKEIDPLELDFLLR--FTVEHTHLSPVDFLTSQSWSAIK 3839
+LFEKDKL F + +LL ++ I+ E FLL +++ + + +L +SW I
Sbjct: 3273 SLFEKDKLLFSFCLTINLLLHERAINKAEWRFLLTGGIGLDNPYANLCTWLPQKSWDEIC 3332
Query: 3840 AIAVMEEFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWK-KKSLIQKLILLRAMRPDR 3898
+ + F+ I R+ W+K +S P E P+EW+ K + Q+++++R +RPD+
Sbjct: 3333 RLDDLPAFKTIRREFMRLKDGWKKVYDSLEPHHEVFPEEWEDKANEFQRMLIIRCLRPDK 3392
Query: 3899 MTYALRNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEILGKRLG 3958
+ L+ F+ +LG ++E DL KAF +S+ P+ F+LSPG D + L L
Sbjct: 3393 VIPMLQEFIINRLGRAFIEPPPFDLAKAFGDSNCCAPLIFVLSPGADPMAAL------LK 3446
Query: 3959 FTIDSG----KFHNVSLGQGQETVAEVALEKASKGGHWVILQNVHLVAKWLGTLEKLLER 4014
F D G K ++SLGQGQ +A LEKA K G WV+LQN HL W+ TLEK+ E
Sbjct: 3447 FADDQGYGGSKLSSLSLGQGQGPIAMKMLEKAVKEGTWVVLQNCHLATSWMPTLEKVCEE 3506
Query: 4015 FS-QGSHRDYRVFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHAALYN---F 4070
S + +H D+R++++ S P+P+ P +L+N +K+TNE P G+ AN+ +
Sbjct: 3507 LSPESTHPDFRMWLT--SYPSPN---FPVSVLQNGVKMTNEAPKGLRANIIRSYLMDPIS 3561
Query: 4071 DQDTLEICSKEQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICASVLYNY 4130
D + C K +EFK +L+ LC+FHA V R +FGP GW+ Y FN DL I L+ +
Sbjct: 3562 DPEFFGSCKKPEEFKKLLYGLCFFHALVQERRKFGPLGWNIPYEFNETDLRISVQQLHMF 3621
Query: 4131 LEANSKVPWEDLRYLFGEIMYGGHITDDWDRKLCRVYLEEFMNPSLTE--DELMLAPG-F 4187
L ++P+E LRY+ GE YGG +TDDWDR+ R L +F NP L E D + G +
Sbjct: 3622 LNQYEELPYEALRYMTGECNYGGRVTDDWDRRTLRSILNKFFNPELVENSDYKFDSSGIY 3681
Query: 4188 AAPPYLDYAGYHQYIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALSG 4247
PP D+ Y +Y + + +P ++G++ NA+I + LF +L Q R+A +G
Sbjct: 3682 FVPPSGDHKSYIEYTKTLPLTPAPEIFGMNANADITKDQSETQLLFDNILLTQSRSAGAG 3741
Query: 4248 DELGQSTEEKVKNVLDDILEKLPEEFNMAEIMQK--NSNRSPYVLVCFQECERMNILIRE 4305
+S++E V V DIL KLP F++ M++ + V QE R N L++
Sbjct: 3742 ---AKSSDEVVNEVASDILGKLPNNFDIEAAMRRYPTTYTQSMNTVLVQEMGRFNKLLKT 3798
Query: 4306 IRISLEQLDLSLKGELALSPAVEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRC 4365
IR S + ++KG +S +E ++ +P+ W +YPS L + ND L R
Sbjct: 3799 IRDSCVNIQKAIKGLAVMSTDLEEVVSSILNVKIPEMWMGKSYPSLKPLGSYVNDFLARL 3858
Query: 4366 RELDTWTQDLTLPAVVWLSGFFNPQSFLTAIMQTMARKNEWPLDKTRLTADVTKKTKEDY 4425
+ L W ++ P V WLSGFF Q+FLT Q ARK P+D L D ++Y
Sbjct: 3859 KFLQQW-YEVGPPPVFWLSGFFFTQAFLTGAQQNYARKYTIPID--LLGFDYEVMEDKEY 3915
Query: 4426 GHPPREGAYLHGLFMEGARWDTQAGTIVEARLKELACPMPVIFAKATPVDRQETKQTYEC 4485
HPP +G ++HGLF++GA W+ + + E+ K L +PV++ K + +Y
Sbjct: 3916 KHPPEDGVFIHGLFLDGASWNRKIKKLAESHPKILYDTVPVMWLKPCKRADIPKRPSYVA 3975
Query: 4486 PVYRTKLR---------GPSYIWTFRLKSEEKTAKWVLAGVALLLE 4522
P+Y+T R +++ L S++ W+ GVALL +
Sbjct: 3976 PLYKTSERRGVLSTTGHSTNFVIAMTLPSDQPKEHWIGRGVALLCQ 4021
>gi|24308169 dynein, axonemal, heavy chain 3 [Homo sapiens]
Length = 4116
Score = 1869 bits (4842), Expect = 0.0
Identities = 1150/3336 (34%), Positives = 1765/3336 (52%), Gaps = 149/3336 (4%)
Query: 1282 LDKANEELEAL--EEEMLQMQESTRLFEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRS 1339
L++A E E + EEE+L+ ++ST Y ++ K + LW
Sbjct: 832 LNRAFAEFELINKEEELLEKEKST---------YPLLQAMLKNKVPYEQLWSTAYEFSIK 882
Query: 1340 IDNWTKTQWRQIHVEQMDVELRRFAKASSITEIWSLNKEVRVWDAYTGLEGTVKDMTASL 1399
+ W ++ EQ+ E+ + + + L K + A L VK
Sbjct: 883 SEEWMNGPLFLLNAEQIAEEIGNMWRTT-----YKLIKTLSDVPAPRRLAENVKIKIDKF 937
Query: 1400 RAITELQS----PALRDRHWHQLMKAIGVKFLINEATTLADLLALRLHRVEDDVRRIVDK 1455
+ + S P ++DRHW Q+ + +G + E T L+++L + + + I
Sbjct: 938 KQYIPILSISCNPGMKDRHWQQISEIVGYEIKPTETTCLSNMLEFGFGKFVEKLEPIGAA 997
Query: 1456 AVKELGTEKVITEISQTWATMKFSYEVHYRTGIPLLKSDEQLFETLEHNQVQLQTLLQSK 1515
A KE EK + + W + FS+ + T +L + + + L+ + ++ QT+ S
Sbjct: 998 ASKEYSLEKNLDRMKLDWVNVTFSFVKYRDTDTNILCAIDDIQMLLDDHVIKTQTMCGSP 1057
Query: 1516 YVEYFIEQVLSWQNKLNIADLVIFTWMEVQRTWSHLESIFVCSEDIRIQLVKDARRFDGV 1575
+++ + W+ KL + W++ Q TW +LE IF SEDI Q+ ++ R+F V
Sbjct: 1058 FIKPIEAECRKWEEKLIRIQDNLDAWLKCQATWLYLEPIF-SSEDIIAQMPEEGRKFGIV 1116
Query: 1576 DAEFKELMFKTAKVENVLEATCRPNLYEKLKDLQSRLSLCEKALAEYLETKRIAFPRFYF 1635
D+ +K LM + K +L A +P + EKL++ L +K L +YLE KR+ FPRF+F
Sbjct: 1117 DSYWKSLMSQAVKDNRILVAADQPRMAEKLQEANFLLEDIQKGLNDYLEKKRLFFPRFFF 1176
Query: 1636 VSSADLLDILSKGAQPKQVTCHLAKLFDSIADLQFEDNQDVSAHRAVGMYSKEKEYVPFQ 1695
+S+ +LL+ILS+ P +V HL K F+ IA L+F DN ++ VGM S EKE VPF
Sbjct: 1177 LSNDELLEILSETKDPLRVQPHLKKCFEGIAKLEFTDNLEI-----VGMISSEKETVPFI 1231
Query: 1696 AE---CECVGHVETWLLQLEQTMQETVRHSITEAIVAYEEKPRELWIFDFPAQVALTSSQ 1752
+ G VE WL Q+EQ M ++R I I AY + PR W+ +P QV + S
Sbjct: 1232 QKIYPANAKGMVEKWLQQVEQMMLASMREVIGLGIEAYVKVPRNHWVLQWPGQVVICVSS 1291
Query: 1753 IWWTTDVGIAFSRLEEGYETALKDFHKKQISQLNTLITLLLGELPPGDRQKIMTICTIDV 1812
I+WT +V A + E L DF KK Q+ ++ L+ G+L G R + + IDV
Sbjct: 1292 IFWTQEVSQALA------ENTLLDFLKKSNDQIAQIVQLVRGKLSSGARLTLGALTVIDV 1345
Query: 1813 HARDVVAKLISQKQVVVSPQAFTWLSQLRHRWEDTQKHCFVNICDAQFQYFYEYLGNSPR 1872
HARDVVAKL + V F W+SQLR+ W K V I + Y YEYLGNSPR
Sbjct: 1346 HARDVVAKLSEDR--VSDLNDFQWISQLRYYW--VAKDVQVQIITTEALYGYEYLGNSPR 1401
Query: 1873 LVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDY 1932
LVITPLTDRCY TL +L L + GAP GPAGTGKTETTKDL +AL VFNCS+ +DY
Sbjct: 1402 LVITPLTDRCYRTLMGALKLNLGGAPEGPAGTGKTETTKDLAKALAKQCVVFNCSDGLDY 1461
Query: 1933 KSIGNIYKGLVQTGAWGCFDEFNRISVEVLSVVAVQVKMIHDAIRNRKKRFVFLGEAITL 1992
K++G +KGL Q GAW CFDEFNRI VEVLSVVA Q+ I AI + K F+F G ++L
Sbjct: 1462 KAMGKFFKGLAQAGAWACFDEFNRIEVEVLSVVAQQILSIQQAIIRKLKTFIFEGTELSL 1521
Query: 1993 KPSVGIFITMNPGYAGRTELPENLKALFRPCAMVAPDIELICEILLVAEGFVDARALARK 2052
P+ +FITMNPGYAGR ELP+NLKALFR AM+ PD LI EI L + GF+D+R+LA+K
Sbjct: 1522 NPTCAVFITMNPGYAGRAELPDNLKALFRTVAMMVPDYALIGEISLYSMGFLDSRSLAQK 1581
Query: 2053 FITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDKNRPEDQVLMRALRDFNMPKI 2112
+ Y LC E LS Q HYD+G+RA+KSVL AG+LK E +L+RAL D N+ K
Sbjct: 1582 IVATYRLCSEQLSSQHHYDYGMRAVKSVLTAAGNLKLKYPEENESVLLLRALLDVNLAKF 1641
Query: 2113 VTDDIPVFLGLVGDLFPALDVPRRRKLHFEQMVRQSTLELRLQPEESFILKVVQLEELLA 2172
+ D+P+F G++ DLFP + +P+ F +++ + +++LQP FI K++Q+ E++
Sbjct: 1642 LAQDVPLFQGIISDLFPGVVLPKPDYEVFLKVLNDNIKKMKLQPVPWFIGKIIQIYEMML 1701
Query: 2173 VRHSVFVVGNAGTGKSKILRTLNRTYVN------MKQKPV-WNDLNPKAVTTDELFGFIH 2225
VRH +VG+ GK+ + L + M++ V + +NPKA+T +L+G
Sbjct: 1702 VRHGYMIVGDPMGGKTSAYKVLAAALGDLHAANQMEEFAVEYKIINPKAITMGQLYGCFD 1761
Query: 2226 HATREWKDGKIVYSYFIGLFSSILREQANLKHDGPKWIVLDGDIDPMWIESLNTVMDDNK 2285
+ EW D G+ ++ REQA+ D KWI+ DG +D +WIE++NTV+DDNK
Sbjct: 1762 QVSHEWMD---------GVLANAFREQASSLSDDRKWIIFDGPVDAIWIENMNTVLDDNK 1812
Query: 2286 VLTLASNERIALTPFMRLLFEIHHLRSATPATVSRAGILYVNPQDLGWNPYVASWIDRRR 2345
L L S E I + M L+FE L A+PATVSR G++Y+ P LGW P S++D
Sbjct: 1813 KLCLMSGEIIQMNSKMSLIFEPADLEQASPATVSRCGMIYMEPHQLGWKPLKDSYMDTLP 1872
Query: 2346 HQSEKANLTILFDKY---VPACLDKLRTSFKTITSIPESSLVQTLCVLLECLLTPENVPS 2402
K + ++ D + V CL+ R K + L ++ L LL
Sbjct: 1873 SSLTKEHKELVNDMFMWLVQPCLEFGRLHCKFVVQTSPIHLAFSMMRLYSSLLDEIRAVE 1932
Query: 2403 DSPKEVYE------------VYFVFACIWAFGGTLLQDQISDYQADFSRWWQ-------- 2442
+ E+ E F+F+ +W GT+ D + F
Sbjct: 1933 EEEMELGEGLSSQQIFLWLQGLFLFSLVWTVAGTINADSRKKFDVFFRNLIMGMDDNHPR 1992
Query: 2443 -KEMKAVK---FPSQGTIFD-YYVDHKTKKLLPWADKIA--QFTMDPDVPLQTVLVHTTE 2495
K +K K FP +G+I+D Y++ + W I + + + +++ T E
Sbjct: 1993 PKSVKLTKNNIFPERGSIYDFYFIKQASGHWETWTQYITKEEEKVPAGAKVSELIIPTME 2052
Query: 2496 TARLRYFMELLLEKGKPLMLVGNAGVGKTVFVGDTLASLSED-YIVSRVPFNYYTTSTAL 2554
TAR +F++ L+ P++ VG G GK+ + L L ++ Y+ + + F+ T++
Sbjct: 2053 TARQSFFLKTYLDHEIPMLFVGPTGTGKSAITNNFLLHLPKNTYLPNCINFSARTSANQT 2112
Query: 2555 QKILEKPLEKKAGHNYGPGGNKKLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYDR 2614
Q I+ L+++ +GP KK + F+DD+NMP ++YG P L+RQ ID+G+W+D+
Sbjct: 2113 QDIIMSKLDRRRKGLFGPPIGKKAVVFVDDLNMPAKEVYGAQPPIELLRQWIDHGYWFDK 2172
Query: 2615 QKVMLKEIHNCQYVACMNPMVGSFT-INPRLQRHFTVFAFNFPSLDALNTIYGQIFSFHF 2673
+ +I + V M P G I R RH + + N D L I+ I +HF
Sbjct: 2173 KDTTRLDIVDMLLVTAMGPPGGGRNDITGRFTRHLNIISINAFEDDILTKIFSSIVDWHF 2232
Query: 2674 QQQAFAPSILRSGPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFASPE 2733
+ F LR G L+QAT ++ + NFLPT K HY+FNLRD S V QG+L
Sbjct: 2233 -GKGFDVMFLRYGKMLVQATKTIYRDAVENFLPTPSKSHYVFNLRDFSRVIQGVLLCPHT 2291
Query: 2734 CLKGPLDLIHLWLHESARVYGDKLIDKKDCDLFQRRMLETAYKYFEGIDSHMLLQ----- 2788
L+ I LW+HE RV+ D+LIDK+D +F + ET F+ +L+
Sbjct: 2292 HLQDVEKCIRLWIHEVYRVFYDRLIDKEDRQVFFNMVKETTSNCFKQTIEKVLIHLSPTG 2351
Query: 2789 -------QPLIY-CHFADRGKDPHYMPVKDWEVLKTILTETLDNYNELN-AAMHLVLFED 2839
+ L + +F Y + D + L ++ L+ +N ++ A M LV+F
Sbjct: 2352 KIVDDNIRSLFFGDYFKPESDQKIYDEITDLKQLTVVMEHYLEEFNNISKAPMSLVMFRF 2411
Query: 2840 AMQHVCRISRILRTPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYGIQELRV 2899
A++H+ RI R+L+ +G LLVG+GGSG+QS ++L+ ++ E++QI +T+ Y + R
Sbjct: 2412 AIEHISRICRVLKQDKGHLLLVGIGGSGRQSAAKLSTFMNAYELYQIEITKNYAGNDWRE 2471
Query: 2900 DLANLYIRTGAKNMPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDKIISGIH 2959
DL + ++ G TVFL D Q+ DESF+ IN LL +G++P++F ++ I+ +
Sbjct: 2472 DLKKIILQVGVATKSTVFLFADNQIKDESFVEDINMLLNTGDVPNIFPADEKADIVEKMQ 2531
Query: 2960 NEVHALG--MVDSRENCWKFFMARVRLQLKIILCFSPVGRTLRVRARKFPAIVNCTAIDW 3017
G + + + + FF+ RV ++ L SP+G R R R FP+++NC IDW
Sbjct: 2532 TAARTQGEKVEVTPLSMYNFFIERVINKISFSLAMSPIGDAFRNRLRMFPSLINCCTIDW 2591
Query: 3018 FHAWPQEALVSVSRRFIEETKGIEPVHKDSISLFMAHVHTTVNEMSTRYYQNERRHNYTT 3077
F +WP +AL V+ +F+E+ + + + + +S+ + +V ++S YY RRHNY T
Sbjct: 2592 FQSWPTDALELVANKFLEDVELDDNIRVEVVSM-CKYFQESVKKLSLDYYNKLRRHNYVT 2650
Query: 3078 PKSFLEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLASQEAELQLR 3137
P S+LE I FK LL K+ EV+ + R + G+QKL ASQV ++ L + + +L L
Sbjct: 2651 PTSYLELILTFKTLLNSKRQEVAMMRNRYLTGLQKLDFAASQVAVMQRELTALQPQLILT 2710
Query: 3138 NHDAEALITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQRECEADLLKAEPALVAA 3197
+ + ++ KI +T + +K + A+E++ + ECE DL +A PAL AA
Sbjct: 2711 SEETAKMMVKIEAETREADGKKLLVQADEKEANVAAAIAQGIKNECEGDLAEAMPALEAA 2770
Query: 3198 TAALNTLNRVNLSELKAFPNPPIAVTNVTAAVMVLLAPRGRVPKDRS---------WKAA 3248
AAL+TLN ++S +K+ NPP V V ++ ++ + D S W +
Sbjct: 2771 LAALDTLNPADISLVKSMQNPPGPVKLVMESICIMKGMKPERKPDPSGSGKMIEDYWGVS 2830
Query: 3249 KVFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLKDPEFNPNLIRTKSFAAAGLCAWVI 3308
K +G + FL++L YDK++IP +K + E ++ PEF P +I+ S A GLC WV
Sbjct: 2831 KKILGDL-KFLESLKTYDKDNIPPLTMKRIRERFINHPEFQPAVIKNVSSACEGLCKWVR 2889
Query: 3309 NIIKFYEVYCDVEPKRQALAQANLELAAATEKLEAIRKKLVDLDRNLSRLTASFEKATAE 3368
+ + V V PKR+ L +A +LAA +KL R +L + L L FE+ +
Sbjct: 2890 AMEVYDRVAKVVAPKRERLREAEGKLAAQMQKLNQKRAELKLVVDRLQALNDDFEEMNTK 2949
Query: 3369 KVRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLLTAAFVSYV 3428
K +E + ++ + A +L+ L +K RW ++ + + L GDVLL++ V+Y+
Sbjct: 2950 KKDLEENIEICSQKLVRAEKLISGLGGEKDRWTEAARQLGIRYTNLTGDVLLSSGTVAYL 3009
Query: 3429 GPFTRQYRQELVHCKWVPFLQQKVSIPLTEGLDLISMLTDDATIAAWNNEGLPSDRMSTE 3488
G FT YR + + +W+ + KV IP L L D I AW GLP D S +
Sbjct: 3010 GAFTVDYRVQCQN-QWLAECKDKV-IPGFSDFSLSHTLGDPIKIRAWQIAGLPVDSFSID 3067
Query: 3489 NAAILTHCERWPLVIDPQQQGIKWIKN-KYGMDLKVTHLGQKGFLNAIETALAFGDVILI 3547
N I+++ RW L+IDP Q KWIKN + L V ++ +E AL G +LI
Sbjct: 3068 NGIIVSNSRRWALMIDPHGQANKWIKNMEKANKLAVIKFSDSNYMRMLENALQLGTPVLI 3127
Query: 3548 ENLEETIDPVLDPLLGRNTIKKG--KYIRIGDKECEFNKNFRLILHTKLANPHYKPELQA 3605
EN+ E +D ++P+L + T K+ +Y+R+G+ E++++F+L + T+L NPHY PE+
Sbjct: 3128 ENIGEELDASIEPILLKATFKQQGVEYMRLGENIIEYSRDFKLYITTRLRNPHYLPEVAV 3187
Query: 3606 QTTLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLEDDLLLRLS 3665
+ LLNF +T GL+ QLL V + E+P+LE+ K L K LK +ED +L LS
Sbjct: 3188 KVCLLNFMITPLGLQDQLLGIVAAKEKPELEEKKNQLIVESAKNKKHLKEIEDKILEVLS 3247
Query: 3666 AAEGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENERKINEARECYRPVAARASLLYFV 3725
++G+ L+D ++ L ++K EI K A E +I+E R Y+PVA ++ ++F
Sbjct: 3248 MSKGNILEDETAIKVLSSSKVLSEEISEKQKVASMTETQIDETRMGYKPVAVHSATIFFC 3307
Query: 3726 INDLQKINPLYQFSLKAFNVLFHRAIEQADKVEDMQGRISILMESITHAVFLYTSQALFE 3785
I+DL I P+YQ+SL F L+ ++ + K E++ RI +++ T +++ ++LFE
Sbjct: 3308 ISDLANIEPMYQYSLTWFINLYMHSLTHSTKSEELNLRIKYIIDHFTLSIYNNVCRSLFE 3367
Query: 3786 KDKLTFLSQMAFQILLRKKEIDPLELDFLLR--FTVEHTHLSPV-DFLTSQSWSAIKAIA 3842
KDKL F + I+ +KKEI FLL +++ + +P +L+ ++W+ I +
Sbjct: 3368 KDKLLFSLLLTIGIMKQKKEITEEVWYFLLTGGIALDNPYPNPAPQWLSEKAWAEIVRAS 3427
Query: 3843 VMEEFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKKSLIQKLILLRAMRPDRMTYA 3902
+ + G+ +E + +W+ +S P +E+LP WK ++K+++LR +RPD+M A
Sbjct: 3428 ALPKLHGLMEHLEQNLGEWKLIYDSAWPHEEQLPGSWKFSQGLEKMVILRCLRPDKMVPA 3487
Query: 3903 LRNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEILGKRLGFTID 3962
+R F+ E +G Y+E DL ++ +SS P+ F+LSP D + L LG +
Sbjct: 3488 VREFIAEHMGKLYIEAPTFDLQGSYNDSSCCAPLIFVLSPSADPMAGLLKFADDLG--MG 3545
Query: 3963 SGKFHNVSLGQGQETVAEVALEKASKGGHWVILQNVHLVAKWLGTLEKLLERFSQGSHRD 4022
+ +SLGQGQ +A + A K G WV+LQN HL A W+ TLEK+ E +
Sbjct: 3546 GTRTQTISLGQGQGPIAAKMINNAIKDGTWVVLQNCHLAASWMPTLEKICEEVIVPESTN 3605
Query: 4023 YRVFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHAALYN---FDQDTLEICS 4079
R + S P+ P +L+N IK+TNEPP G+ ANL + N D + C+
Sbjct: 3606 ARFRLWLTSYPSEK---FPVSILQNGIKMTNEPPKGLRANLLRSYLNDPISDPVFFQSCA 3662
Query: 4080 KEQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICASVLYNYLEANSKVPW 4139
K ++ +LF LC+FHA V R FGP GW+ Y FN DL I + +L +VP+
Sbjct: 3663 KAVMWQKMLFGLCFFHAVVQERRNFGPLGWNIPYEFNESDLRISMWQIQMFLNDYKEVPF 3722
Query: 4140 EDLRYLFGEIMYGGHITDDWDRKLCRVYLEEFMNPSLTEDELMLAPG--FAAPPYLDYAG 4197
+ L YL GE YGG +TDD DR+L L F + ED LAPG + PP+ Y
Sbjct: 3723 DALTYLTGECNYGGRVTDDKDRRLLLSLLSMFYCKEIEEDYYSLAPGDTYYIPPHGSYQS 3782
Query: 4198 YHQYIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALSGDELGQSTEEK 4257
Y Y+ + P ++GLH NA+I +N LF +L PR SG G+S +E
Sbjct: 3783 YIDYLRNLPITAHPEVFGLHENADITKDNQETNQLFEGVLLTLPRQ--SGGS-GKSPQEV 3839
Query: 4258 VKNVLDDILEKLPEEFNMAEIMQKNS--NRSPYVLVCFQECERMNILIREIRISLEQLDL 4315
V+ + DIL KLP +F++ E+M+ V QE R N L + +R SL L
Sbjct: 3840 VEELAQDILSKLPRDFDLEEVMKLYPVVYEESMNTVLRQELIRFNRLTKVVRRSLINLGR 3899
Query: 4316 SLKGELALSPAVEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRELDTWTQDL 4375
++KG++ +S +E ++ VP W+ +YPS L + DLL R W D
Sbjct: 3900 AIKGQVLMSSELEEVFNSMLVGKVPAMWAAKSYPSLKPLGGYVADLLARLTFFQEWI-DK 3958
Query: 4376 TLPAVVWLSGFFNPQSFLTAIMQTMARKNEWPLDKTRLTADVTKKTKEDYGHPPREGAYL 4435
P V W+SGF+ QSFLT + Q ARK P+D +VT + + + P +GAY+
Sbjct: 3959 GPPVVFWISGFYFTQSFLTGVSQNYARKYTIPIDHIGFEFEVTPQ-ETVMENNPEDGAYI 4017
Query: 4436 HGLFMEGARWDTQAGTIVEARLKELACPMPVIFAKATPVDRQETKQTYECPVYRTKLR-- 4493
GLF+EGARWD + I E+ K L P+P+I+ K + Y CPVY+T R
Sbjct: 4018 KGLFLEGARWDRKTMQIGESLPKILYDPLPIIWLKPGESAMFLHQDIYVCPVYKTSARRG 4077
Query: 4494 -------GPSYIWTFRLKSEEKTAKWVLAGVALLLE 4522
+Y+ + L ++ W+ GVA L +
Sbjct: 4078 TLSTTGHSTNYVLSIELPTDMPQKHWINRGVASLCQ 4113
>gi|19115954 dynein, axonemal, heavy chain 5 [Homo sapiens]
Length = 4624
Score = 1831 bits (4743), Expect = 0.0
Identities = 1179/3697 (31%), Positives = 1920/3697 (51%), Gaps = 162/3697 (4%)
Query: 925 HDLDFFLKNTEKQLKP--APFFQAQMILLPPEIVFKPSLD-----------------REA 965
H ++F N+ +K P F+A + L P IV P+L+ +
Sbjct: 989 HTINFRDSNSASNMKQNSLPIFRASVTLAIPNIVMAPALEDVQQTLNKAVECIISVPKGV 1048
Query: 966 GDGFYDLVEEMLCNSFRMSAQMNRIATHLEIKNYQNDMDNMLGLAEVRQEIMNRVVNVIN 1025
+L+ + +M+A + + +++ +N++ + L +A V I + N
Sbjct: 1049 RQWSSELLSKKKIQERKMAALQSNEDSDSDVEMGENELQDTLEIASVNLPIPVQTKNYYK 1108
Query: 1026 KVLDFRNTLETHTYLWV------DDRAEFMKHFLLYGHAVSSDEMDAHANEEIPEQPPTL 1079
V + + ++ + L + M F Y H + +A + Q P L
Sbjct: 1109 NVSENKEIVKLVSVLSTIINSTKKEVITSMDCFKRYNHIWQKGKEEAI--KTFITQSPLL 1166
Query: 1080 EQFKEQIDIYEALYVQMSKFEDFRVFDSWFKVDMKPFKVSLLTIIKKWSWMFQEHLLRFV 1139
+F+ QI ++ L +++ ++ S + K +L K W + H +
Sbjct: 1167 SEFESQILYFQNLEQEINAEPEYVCVGS-IALYTADLKFALTAETKAWMVVIGRHCNKKY 1225
Query: 1140 IDSLNELQEFIKETDSGLQRELNEGDHDGLVDIMVHLLAVRSRQRATDELFEPLKETITL 1199
+ + I+E + L R + D D + M L +R Q + D P++E+ L
Sbjct: 1226 RSEMENIFMLIEEFNKKLNRPIK--DLDDIRIAMAALKEIREEQISIDFQVGPIEESYAL 1283
Query: 1200 LESYGQKMPEQVYIQLEELPERWETTKKIAATVRHEVSPLHNAEVTLIRKKCILFDAKQA 1259
L YG + + +++ L WE A V++++ L + +K+ L A +
Sbjct: 1284 LNRYGLLIAREEIDKVDTLHYAWEKLLARAGEVQNKLVSLQPS----FKKE--LISAVEV 1337
Query: 1260 EFRERFRHYAPLGFNAE-----NPYTALDKA---NEELEALEEEMLQMQESTRLFEVALP 1311
++ + Y N P A D+ + + + + + LF +
Sbjct: 1338 FLQDCHQFYLDYDLNGPMASGLKPQEASDRLIMFQNQFDNIYRKYITYTGGEELFGLPAT 1397
Query: 1312 EYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTKTQWRQIHVEQMDVELRRFAKASSITE 1371
+Y Q+ + +K++ LL+ ++ + V +++++ W ++++E+++ EL F
Sbjct: 1398 QYPQLLEIKKQLNLLQKIYTLYNSVIETVNSYYDILWSEVNIEKINNELLEFQNRCR--- 1454
Query: 1372 IWSLNKEVRVWDAYTGLEGTVKDMTASLRAITELQSPALRDRHWHQLMKAIGVKFLI-NE 1430
L + ++ W A+ L+ + D + + + S A+ +RHW ++ G + NE
Sbjct: 1455 --KLPRALKDWQAFLDLKKIIDDFSECCPLLEYMASKAMMERHWERITTLTGHSLDVGNE 1512
Query: 1431 ATTLADLLALRLHRVEDDVRRIVDKAVKELGTEKVITEISQTWATMKFSYEVHYRTGIPL 1490
+ L +++ L + ++++ I AVKE E+ + ++ W F++ G L
Sbjct: 1513 SFKLRNIMEAPLLKYKEEIEDICISAVKERDIEQKLKQVINEWDNKTFTFGSFKTRGELL 1572
Query: 1491 LKSDE--QLFETLEHNQVQLQTLLQSKYVEYFIEQVLSWQNKLNIADLVIFTWMEVQRTW 1548
L+ D ++ +E + + L +LL ++Y F Q+ W L+ + +I +WM VQ W
Sbjct: 1573 LRGDSTSEIIANMEDSLMLLGSLLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLW 1632
Query: 1549 SHLESIFVCSEDIRIQLVKDARRFDGVDAEFKELMFKTAKVENVLEATCRPN-LYEKLKD 1607
+LE++FV DI QL K+A+RF +D + ++M + +V +V++ L + L
Sbjct: 1633 IYLEAVFV-GGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPH 1691
Query: 1608 LQSRLSLCEKALAEYLETKRIAFPRFYFVSSADLLDILSKGAQPKQVTCHLAKLFDSIAD 1667
L +L +C+K+L YLE KR+ FPRF+FVS LL+IL + + + HL +FD+I
Sbjct: 1692 LLDQLEICQKSLTGYLEKKRLCFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKS 1751
Query: 1668 LQFEDNQDVSAHRAVGMYSKEKEYVPFQAECECVGHVETWLLQLEQTMQETVRHSITEAI 1727
++F + R + + S+E E + G+VE WL L + Q ++ I +A
Sbjct: 1752 VKFHEK---IYDRILSISSQEGETIELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAA 1808
Query: 1728 VAYEEKPRELWIF--DFPAQVALTSSQIWWTTDVGIAFSRLEEGYETALKDFHKKQISQL 1785
+E +L F FPAQV L Q+ WT D A R + + ++ ++ + L
Sbjct: 1809 ANIQETGFQLTEFLSSFPAQVGLLGIQMIWTRDSEEAL-RNAKFDKKIMQKTNQAFLELL 1867
Query: 1786 NTLITLLLGELPPGDRQKIMTICTIDVHARDVVAKLISQKQVVVSPQAFTWLSQLRHRWE 1845
NTLI + +L +R K T+ TI VH RD+ L + SP F WL Q R +
Sbjct: 1868 NTLIDVTTRDLSSTERVKYETLITIHVHQRDIFDDLCHMH--IKSPMDFEWLKQCRFYFN 1925
Query: 1846 DTQKHCFVNICDAQFQYFYEYLGNSPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTG 1905
+ ++I D F Y E+LG + RLVITPLTDRCYITL Q+L ++M GAPAGPAGTG
Sbjct: 1926 EDSDKMMIHITDVAFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTG 1985
Query: 1906 KTETTKDLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGAWGCFDEFNRISVEVLSVV 1965
KTETTKD+GR LG V VFNCS+QMD++ +G I+KGL Q+G+WGCFDEFNRI + VLSV
Sbjct: 1986 KTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVA 2045
Query: 1966 AVQVKMIHDAIRNRKKRFVFL-GEAITLKPSVGIFITMNPGYAGRTELPENLKALFRPCA 2024
A Q+ +I + KK F+F G+ +T+ P G+F+TMNPGYAGR ELPENLK FR A
Sbjct: 2046 AQQISIILTCKKEHKKSFIFTDGDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVA 2105
Query: 2025 MVAPDIELICEILLVAEGFVDARALARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVA 2084
M+ PD ++I + L + GF+D LARKF TLY LC+E LSKQ HYD+GLR I SVL
Sbjct: 2106 MMVPDRQIIIRVKLASCGFIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTL 2165
Query: 2085 GSLKRGDKNRPEDQVLMRALRDFNMPKIVTDDIPVFLGLVGDLFPALDVPRRRKLHFEQM 2144
G+ KR + E ++MR LRD N+ K++ +D P+FL L+ DLFP + + + E
Sbjct: 2166 GAAKRANPMDTESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYPELEAA 2225
Query: 2145 VRQSTLELRLQPEESFILKVVQLEELLAVRHSVFVVGNAGTGKSKILRTLNRTYVNMKQK 2204
+ + E L + LKV+QL E VRH + +G +G GK+ + TL R + +
Sbjct: 2226 ISRQVEEAGLINHPPWKLKVIQLFETQRVRHGMMTLGPSGAGKTTCIHTLMRAMTDCGKP 2285
Query: 2205 PVWNDLNPKAVTTDELFGFIHHATREWKDGKIVYSYFIGLFSSILREQANLKHDGPKWIV 2264
+NPKA+T ++FG + AT +W D G+FS++ R+ K WI+
Sbjct: 2286 HREMRMNPKAITAPQMFGRLDVATNDWTD---------GIFSTLWRKTLRAKKGEHIWII 2336
Query: 2265 LDGDIDPMWIESLNTVMDDNKVLTLASNERIALTPFMRLLFEIHHLRSATPATVSRAGIL 2324
LDG +D +WIE+LN+V+DDNK LTLA+ +RI + P +++FE H++ +A+PATVSR G++
Sbjct: 2337 LDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNASPATVSRNGMV 2396
Query: 2325 YVNPQDLGWNPYVASWIDRRRHQSEKANLTILFDKYVPACLDKLRTSFKTI---TSIPES 2381
+++ L W+P + ++ +R Q + IL Y + D R + + + E+
Sbjct: 2397 FMSSSILDWSPILEGFLKKRSPQEAE----ILRQLYTESFPDLYRFCIQNLEYKMEVLEA 2452
Query: 2382 SLVQTLCVLLECLLTPENVPSDSPKEVYEVYFVFACIWAFGGTLLQDQISDYQADFSRWW 2441
++ +L+ L+ + + + FVFA +W+ G L D + W
Sbjct: 2453 FVITQSINMLQGLIPLKEQGGEVSQAHLGRLFVFALLWSAGAALELDG----RRRLELWL 2508
Query: 2442 Q-KEMKAVKFPSQG----TIFDYYVDHKTKKLLPWADKIAQFTMDPDVPLQ--TVLVHTT 2494
+ + ++ P T FDYYV W + ++ D + ++LV
Sbjct: 2509 RSRPTGTLELPPPAGPGDTAFDYYV-APDGTWTHWNTRTQEYLYPSDTTPEYGSILVPNV 2567
Query: 2495 ETARLRYFMELLLEKGKPLMLVGNAGVGKTVFVGDTLASLS-EDYIVSRVPFNYYTTSTA 2553
+ R + ++ + ++GK ++L+G G KTV + ++ E +++ + F+ TT
Sbjct: 2568 DNVRTDFLIQTIAKQGKAVLLIGEQGTAKTVIIKGFMSKYDPECHMIKSLNFSSATTPLM 2627
Query: 2554 LQKILEKPLEKKAGHNYGPGGNKKLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYD 2613
Q+ +E ++K+ G YGP KK+ FIDD+NMP ++ +G + ++RQ ++ +Y+
Sbjct: 2628 FQRTIESYVDKRMGTTYGPPAGKKMTVFIDDVNMPIINEWGDQVTNEIVRQLMEQNGFYN 2687
Query: 2614 RQKV-MLKEIHNCQYVACM-NPMVGSFTINPRLQRHFTVFAFNFPSLDALNTIYGQIFSF 2671
+K I + Q++A M +P G I RL+R F++F PS +++ I+G I
Sbjct: 2688 LEKPGEFTSIVDIQFLAAMIHPGGGRNDIPQRLKRQFSIFNCTLPSEASVDKIFGVIGVG 2747
Query: 2672 HF-QQQAFAPSILRSGPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFA 2730
H+ Q+ F+ + S L+ T Q LPT KFHY+FNLRDLS V+QG+L
Sbjct: 2748 HYCTQRGFSEEVRDSVTKLVPLTRRLWQMTKIKMLPTPAKFHYVFNLRDLSRVWQGMLNT 2807
Query: 2731 SPECLKGPLDLIHLWLHESARVYGDKLIDKKDCDLFQRRMLETAYKYFE---------GI 2781
+ E +K P DL+ LW HE RV D+ D F + ++ + F GI
Sbjct: 2808 TSEVIKEPNDLLKLWKHECKRVIADRFTVSSDVTWFDKALVSLVEEEFGEEKKLLVDCGI 2867
Query: 2782 DSH---MLLQQPLI---YCHFADRGKDPHYMPVKDWEVLKTILTETLDNYNE--LNAAMH 2833
D++ L P AD Y P++ + LK L L YNE A M
Sbjct: 2868 DTYFVDFLRDAPEAAGETSEEADAETPKIYEPIESFSHLKERLNMFLQLYNESIRGAGMD 2927
Query: 2834 LVLFEDAMQHVCRISRILRTPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYG 2893
+V F DAM H+ +ISR++RTPQG ALLVGVGGSGKQSL+RLA+++ G FQITLT Y
Sbjct: 2928 MVFFADAMVHLVKISRVIRTPQGNALLVGVGGSGKQSLTRLASFIAGYVSFQITLTRSYN 2987
Query: 2894 IQELRVDLANLYIRTGAKNMPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDK 2953
L DL LY G + F+ TD ++ DESFL +N++L+SGE+ +LF+ +++D+
Sbjct: 2988 TSNLMEDLKVLYRTAGQQGKGITFIFTDNEIKDESFLEYMNNVLSSGEVSNLFARDEIDE 3047
Query: 2954 IISGIHN--EVHALGMVDSRENCWKFFMARVRLQLKIILCFSPVGRTLRVRARKFPAIVN 3011
I S + + + + + EN +FM+RVR L I+LCFSPVG R RA KFPA+++
Sbjct: 3048 INSDLASVMKKEFPRCLPTNENLHDYFMSRVRQNLHIVLCFSPVGEKFRNRALKFPALIS 3107
Query: 3012 CTAIDWFHAWPQEALVSVSRRFIEETK-GIEPVHKDSISLFMAHVHTTVNEMSTRYYQNE 3070
IDWF WP++ALV+VS F+ K + M V E Y+Q
Sbjct: 3108 GCTIDWFSRWPKDALVAVSEHFLTSYDIDCSLEIKKEVVQCMGSFQDGVAEKCVDYFQRF 3167
Query: 3071 RRHNYTTPKSFLEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLASQ 3130
RR + TPKS+L I +K + +K EV R+ G++KLK + V L L ++
Sbjct: 3168 RRSTHVTPKSYLSFIQGYKFIYGEKHVEVRTLANRMNTGLEKLKEASESVAALSKELEAK 3227
Query: 3131 EAELQLRNHDAEALITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQRECEADLLKA 3190
E ELQ+ N A+ ++ ++ ++ + + K + + AI + + + E L A
Sbjct: 3228 EKELQVANDKADMVLKEVTMKAQAAEKVKAEVQKVKDRAQAIVDSISKDKAIAEEKLEAA 3287
Query: 3191 EPALVAATAALNTLNRVNLSELKAFPNPPIAVTNVTAAVMVLLAPRGRVPK--------D 3242
+PAL A AAL T+ +++ ++ PP + + V++L + K
Sbjct: 3288 KPALEEAEAALQTIRPSDIATVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKIDLEKSCTM 3347
Query: 3243 RSWKAAKVFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLKDPEFNPNLIRTKSFAAAG 3302
SW+ + M +FLQ L + K+ I E ++ ++ Y + P++N + AG
Sbjct: 3348 PSWQESLKLM-TAGNFLQNLQQFPKDTINEEVIEFLSP-YFEMPDYNIETAKRVCGNVAG 3405
Query: 3303 LCAWVINIIKFYEVYCDVEP-KRQALAQANLELAAATEKLEAIRKKLVDLDRNLSRLTAS 3361
LC+W + F+ + +V P K + Q N L A + L+ + +L D L + A
Sbjct: 3406 LCSWTKAMASFFSINKEVLPLKANLVVQENRHL-LAMQDLQKAQAELDDKQAELDVVQAE 3464
Query: 3362 FEKATAEKVRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLLT 3421
+E+A EK E+ + ++ A+ L+ L +K RW + + F AQ K L GDVLL
Sbjct: 3465 YEQAMTEKQTLLEDAERCRHKMQTASTLISGLAGEKERWTEQSQEFAAQTKRLVGDVLLA 3524
Query: 3422 AAFVSYVGPFTRQYRQELVHCKWVPFLQQKVSIPLTEGLDLISMLTDDATIAAWNNEGLP 3481
AF+SY GPF +++R L++ W ++ + IP + L+L ML D TI+ WN +GLP
Sbjct: 3525 TAFLSYSGPFNQEFRDLLLN-DWRKEMKAR-KIPFGKNLNLSEMLIDAPTISEWNLQGLP 3582
Query: 3482 SDRMSTENAAILTHCERWPLVIDPQQQGIKWIKNKYGM-DLKVTHLGQKGFLNAIETALA 3540
+D +S +N I+T R+PL+IDPQ QG WIKNK +L++T L K F N +E +L+
Sbjct: 3583 NDDLSIQNGIIVTKASRYPLLIDPQTQGKIWIKNKESRNELQITSLNHKYFRNHLEDSLS 3642
Query: 3541 FGDVILIENLEETIDPVLDPLLGRNTIKKGK--YIRIGDKECEFNKNFRLILHTKLANPH 3598
G +LIE++ E +DP LD +L RN IK G +++GDKE + FRL + TKL NP
Sbjct: 3643 LGRPLLIEDVGEELDPALDNVLERNFIKTGSTFKVKVGDKEVDVLDGFRLYITTKLPNPA 3702
Query: 3599 YKPELQAQTTLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLED 3658
Y PE+ A+T++++FTVT GLE QLL V+ E+ +LEK + L + K +K LED
Sbjct: 3703 YTPEISARTSIIDFTVTMKGLEDQLLGRVILTEKQELEKERTHLMEDVTANKRRMKELED 3762
Query: 3659 DLLLRLSAAEGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENERKINEARECYRPVAAR 3718
+LL RL++ +GS ++D L+ L TK T E+ K+ + E E +IN ARE YRPVA R
Sbjct: 3763 NLLYRLTSTQGSLVEDESLIVVLSNTKRTAEEVTQKLEISAETEVQINSAREEYRPVATR 3822
Query: 3719 ASLLYFVINDLQKINPLYQFSLKAFNVLFHRAIEQADKVEDMQGRISILMESITHAVFLY 3778
S+LYF+I +++ +N +YQ SL+ F LF ++ ++ K RI+ ++E +T+ V+ Y
Sbjct: 3823 GSILYFLITEMRLVNEMYQTSLRQFLGLFDLSLARSVKSPITSKRIANIIEHMTYEVYKY 3882
Query: 3779 TSQALFEKDKLTFLSQMAFQILLRKKEIDPLELDFLLR----FTVEHTHLSPVDFLTSQS 3834
++ L+E+ K F + +I +++ + E L++ ++ P ++ +
Sbjct: 3883 AARGLYEEHKFLFTLLLTLKIDIQRNRVKHEEFLTLIKGGASLDLKACPPKPSKWILDIT 3942
Query: 3835 WSAIKAIAVMEEFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKK-SLIQKLILLRA 3893
W + ++ + +F + + + K W+ W + E PE+E LP + K ++L+L+R+
Sbjct: 3943 WLNLVELSKLRQFSDVLDQISRNEKMWKIWFDKENPEEEPLPNAYDKSLDCFRRLLLIRS 4002
Query: 3894 MRPDRMTYALRNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEIL 3953
PDR R ++ + +G KY E LDL K +EES P TP+ +LS G D + L
Sbjct: 4003 WCPDRTIAQARKYIVDSMGEKYAEGVILDLEKTWEESDPRTPLICLLSMGSDPTDSIIAL 4062
Query: 3954 GKRLGFTIDSGKFHNVSLGQGQETVAEVALEKASKGGHWVILQNVHLVAKWLGTLEKLLE 4013
GKRL + VS+GQGQE A L++ G W +LQN HL ++ L ++
Sbjct: 4063 GKRLKI-----ETRYVSMGQGQEVHARKLLQQTMANGGWALLQNCHLGLDFMDELMDIII 4117
Query: 4014 RFSQGSHRDYRVFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHAALYNFDQD 4073
++ H +R++M+ E+ P LL+ SIK N+PP G+ A L QD
Sbjct: 4118 E-TELVHDAFRLWMTTEA-----HKQFPITLLQMSIKFANDPPQGLRAGLKRTYSGVSQD 4171
Query: 4074 TLEICSKEQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICASVLYNYL-- 4131
L++ S Q +K +L+++ + H+ V R +FG GW+ Y FN D + N+L
Sbjct: 4172 LLDVSSGSQ-WKPMLYAVAFLHSTVQERRKFGALGWNIPYEFNQADFNATVQFIQNHLDD 4230
Query: 4132 -EANSKVPWEDLRYLFGEIMYGGHITDDWDRKLCRVYLEEFMNPSLTEDELMLAPGFAAP 4190
+ V W +RY+ GEI YGG +TDD+D++L + + + + ++ + G+ P
Sbjct: 4231 MDVKKGVSWTTIRYMIGEIQYGGRVTDDYDKRLLNTFAKVWFSENMFGPDFSFYQGYNIP 4290
Query: 4191 PYLDYAGYHQYIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALSGDEL 4250
Y QYI+ + +SP ++GLHPNA+I + + + + T+L +QP++ G +
Sbjct: 4291 KCSTVDNYLQYIQSLPAYDSPEVFGLHPNADITYQSKLAKDVLDTILGIQPKDTSGGGD- 4349
Query: 4251 GQSTEEKVKNVLDDILEKLPEE---FNMAEIMQKNSNRSPYVLVCFQECERMNILIREIR 4307
++ E V + DD+LEKLP + F + E +QK P + QE +RM ++ +R
Sbjct: 4350 -ETREAVVARLADDMLEKLPPDYVPFEVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLVR 4408
Query: 4308 ISLEQLDLSLKGELALSPAVEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRE 4367
+L +L L++ G + +S + + +P W K ++ S+ L WF +L+ R +
Sbjct: 4409 STLTELKLAIDGTIIMSENLRDALDCMFDARIPAWWKKASWISS-TLGFWFTELIERNSQ 4467
Query: 4368 LDTWTQDLTLPAVVWLSGFFNPQSFLTAIMQTMARKNE-WPLDKTRLTADVTKKTKEDYG 4426
+W + P W++GFFNPQ FLTA+ Q + R N+ W LD L +VTK K+D
Sbjct: 4468 FTSWVFN-GRPHCFWMTGFFNPQGFLTAMRQEITRANKGWALDNMVLCNEVTKWMKDDIS 4526
Query: 4427 HPPREGAYLHGLFMEGARWDTQAGTIVEARLKELACPMPVIFAKATPVDRQETKQTYECP 4486
PP EG Y++GL++EGA WD + ++E++ K L MPVI A ++ + Y CP
Sbjct: 4527 APPTEGVYVYGLYLEGAGWDKRNMKLIESKPKVLFELMPVIRIYAENNTLRDPR-FYSCP 4585
Query: 4487 VYRTKLRGP-SYIWTFRLKSEEKTAKWVLAGVALLLE 4522
+Y+ +R +YI L++ + WVL GVALL +
Sbjct: 4586 IYKKPVRTDLNYIAAVDLRTAQTPEHWVLRGVALLCD 4622
Score = 167 bits (424), Expect = 2e-40
Identities = 168/753 (22%), Positives = 311/753 (41%), Gaps = 68/753 (9%)
Query: 128 FISKKITESIGVNDFSQVVLFGELPALS---LGHVSAFLDEILVPVLSNKNNHKSWSCFT 184
FI +++I ++ Q V F L A L V L +I +P L +H
Sbjct: 130 FIRTDPSKAITPDNIHQEVSFNMLDAADGGLLNSVRRLLSDIFIPAL-RATSHGWGELEG 188
Query: 185 SQD-----------MEYHIEVMKKKMYIFRGKMSRRTLLPIPTVAGKMDLDQNCSENKPP 233
QD +E + V+ + K++ R + K D N P
Sbjct: 189 LQDAANIRQEFLSSLEGFVNVLSGAQESLKEKVNLRKCDILELKTLKEPTDYLTLANNPE 248
Query: 234 SNERIILHAIESVVIEWSHQIQEIIERDSVQRLLNGLHLSPQAELDFWMMRRENLSCIYD 293
+ L IE + W Q ++++ ++ Q L + P+AEL+ W R + + +
Sbjct: 249 T-----LGKIEDCMKVWIKQTEQVLAENN-QLLKEADDVGPRAELEHWKKRLSKFNYLLE 302
Query: 294 QLQAPVVLKMVKILTTKQSSYFPTLKDIFLAVENALLEAQDVELYLRPLRRHIQCLQETE 353
QL++P V ++ +L +S T +++ + + +A EA+D YL L + L ++
Sbjct: 303 QLKSPDVKAVLAVLAAAKSKLLKTWREMDIRITDATNEAKDNVKYLYTLEKCCDPLYSSD 362
Query: 354 FPQTRILIAPLFHTICLIWSHSKFYNTPARVIVLLQEFCNLFINQATAYLS--------- 404
I L + I +I+S S +YNT ++ L + N I+ AY++
Sbjct: 363 PLSMMDAIPTLINAIKMIYSISHYYNTSEKITSLFVKVTNQIISACKAYITNNGTASIWN 422
Query: 405 -PEDLLRGEIEESLEKVQVAVNILKTFKNSFFNYRKKLASYFMGRKLRPWDFQSHLVFCR 463
P+D++ EK+ A+ + + ++ F ++KL + +DF +F +
Sbjct: 423 QPQDVVE-------EKILSAIKLKQEYQLCFHKTKQKLK---QNPNAKQFDFSEMYIFGK 472
Query: 464 FDKFLDRLIKIEDIFATTLEFEKLERLEFGGTKGAILNGQVHEMSEELMELCKLFKQSTY 523
F+ F RL KI DIF T + L+ G + +M+ + + K+ Y
Sbjct: 473 FETFHRRLAKIIDIFTTLKTYSVLQDSTIEG---------LEDMATKYQGIVATIKKKEY 523
Query: 524 DPSDCTNMEFESDYVAFKSKTLEFDRRLGTIICEAFFNCNGLEAAFKLLTIFGNFLEKPV 583
+ D M+F+ DY F +T + L + F A ++L F E+
Sbjct: 524 NFLDQRKMDFDQDYEEFCKQTNDLHNELRKFMDVTFAKIQNTNQALRMLKKF----ERLN 579
Query: 584 VMEI-FSLHYSTLVHMFNTELDVCKQLYNEHMKQIECGHVVLNKNMPFTSGNMKWAQQVL 642
+ + Y ++ + ++D+ +LY + L +N P +G + WA+Q+
Sbjct: 580 IPNLGIDDKYQLILENYGADIDMISKLYTKQKYD-----PPLARNQPPIAGKILWARQLF 634
Query: 643 QRLQMFWSNFASLRYLFLGNPDHALVYQKYVEMTTLLDQFESRIYNEWKSNVDEICEFNL 702
R+Q F L + + + Y M +L +FE + W ++EI L
Sbjct: 635 HRIQQPMQLFQQ-HPAVLSTAEAKPIIRSYNRMAKVLLEFEVLFHRAWLRQIEEI-HVGL 692
Query: 703 NQPLVKFSAINGLLCVNFDPKLVAVLREVKYLLMLKKQDIPDSALAIFKKRNTILKYIGN 762
L+ + G L VNFDP+++ + RE + + + + P A ++F+KR+ + N
Sbjct: 693 EASLLVKAPGTGELFVNFDPQILILFRETECMAQMGLEVSP-LATSLFQKRDRYKRNFSN 751
Query: 763 LDLLVQGYNKLKQTLLEVEYPLIEDELRAIDEQLTAATTWLTWQD-DCWGYIERVRAATS 821
+ +++ Y ++K + LI L +DE L LTW + Y+E A
Sbjct: 752 MKMMLAEYQRVKSKIPAAIEQLIVPHLAKVDEALQPGLAALTWTSLNIEAYLENTFAKIK 811
Query: 822 ELEHRVERT----QKNVKVIQQTMRGWARCVLP 850
+LE ++R + + I + M C LP
Sbjct: 812 DLELLLDRVNDLIEFRIDAILEEMSSTPLCQLP 844
>gi|126012497 dynein, axonemal, heavy polypeptide 8 [Homo sapiens]
Length = 4490
Score = 1825 bits (4726), Expect = 0.0
Identities = 1150/3573 (32%), Positives = 1879/3573 (52%), Gaps = 138/3573 (3%)
Query: 1016 IMNRVVNVINKVL-DFRNTLETHTYLWVDDRAEFMKHFLLYGHAVSSDEMDAHANEEIPE 1074
+++ VN + K + + + LW +DR +K FL AN
Sbjct: 988 LLSSSVNSLRKAAHEALQDFQKYKTLWTEDRDVKVKEFL--------------ANN---- 1029
Query: 1075 QPPTLEQFKEQIDIYEALYVQMSKFEDFRVFDSWFKVDMKPFKVSLLTIIKKWSWMFQEH 1134
P+L + + +I Y ++ + + V + ++ +P K++L K W + +
Sbjct: 1030 --PSLTEIRSEILHYATFEQEIDELKPIIVVGA-LELHTEPMKLALSIEAKAWKMLLCRY 1086
Query: 1135 LLRFVIDSLNELQEFIKETDSGLQRELNEGDHDGLVDIMVHLLAVRSRQRATDELFEPLK 1194
L ++ + FI E L R + D D + M L +R + D P++
Sbjct: 1087 LNEEYKKKMSYMIAFINEYLKKLSRPIR--DLDDVRFAMEALSCIRDNEIQMDMTLGPIE 1144
Query: 1195 ETITLLESYGQKMPEQVYIQLEELPERWETTKKIAATVRHEVSPLHNAEVTLIRKKCILF 1254
E +L + ++ ++ ++ L + + A +V+ ++ + + + + +F
Sbjct: 1145 EAYAILNRFEVEVTKEESEAVDTLRYSFNKLQSKAVSVQEDLVQVQPKFKSNLLESVEVF 1204
Query: 1255 DAKQAEFRERFRHYAPLGFNA--ENPYTALDKANEELEALEEEMLQMQESTRLFEVALPE 1312
F E + P+ N + L + L + + +LF + + +
Sbjct: 1205 REDVINFAEAYELEGPMVPNIPPQEASNRLQIFQASFDDLWRKFVTYSSGEQLFGLPVTD 1264
Query: 1313 YKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTKTQWRQIHVEQMDVELRRFAKASSITEI 1372
Y+ + + RKE+ LL+ L+ + V SI + + W + +E+++ EL F
Sbjct: 1265 YEVLHKTRKELNLLQKLYGLYDTVMSSISGYYEILWGDVDIEKINAELLEFQNRCR---- 1320
Query: 1373 WSLNKEVRVWDAYTGLEGTVKDMTASLRAITELQSPALRDRHWHQLMKAIGVKFLI-NEA 1431
L K ++ W A+ L+ + D + S + + + A++ RHW ++ + G F + +++
Sbjct: 1321 -KLPKGLKDWQAFLDLKKRIDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDS 1379
Query: 1432 TTLADLLALRLHRVEDDVRRIVDKAVKELGTEKVITEISQTWATMKFSYEVHYRTGIPLL 1491
L +++ L + +DD+ I A+KE E +T++ + W S+ G LL
Sbjct: 1380 FCLRNIMEAPLLKHKDDIEDICISAIKEKDIEAKLTQVIENWTNQNLSFAAFKGKGELLL 1439
Query: 1492 KSDE--QLFETLEHNQVQLQTLLQSKYVEYFIEQVLSWQNKLNIADLVIFTWMEVQRTWS 1549
K E ++ +E + + L +LL ++Y F + + +W KL+ + +I W+ VQ W
Sbjct: 1440 KGTESGEIITLMEDSLMVLGSLLSNRYNAPFKKNIQNWVYKLSTSSDIIEEWLVVQNLWV 1499
Query: 1550 HLESIFVCSEDIRIQLVKDARRFDGVDAEFKELMFKTAKVENVLEATCRPN-LYEKLKDL 1608
+LE++FV DI QL ++A+RF +D + ++M + + NV+ + + L L
Sbjct: 1500 YLEAVFV-GGDIAKQLPQEAKRFQNIDKSWIKIMQRAHENPNVINCCVGDETMGQLLPHL 1558
Query: 1609 QSRLSLCEKALAEYLETKRIAFPRFYFVSSADLLDILSKGAQPKQVTCHLAKLFDSIADL 1668
+L +C+K+L YLE KR+ FPRF+FVS LL+IL + + + HL + D+I ++
Sbjct: 1559 HEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEV 1618
Query: 1669 QFEDNQDVSAHRAVGMYSKEKEYVPFQAECECVGHVETWLLQLEQTMQETVRHSITEAIV 1728
F R + + S+E E + G VE WLL L + ++ + I A
Sbjct: 1619 TFHAKD---YDRIMAVISREGEKIVLDNSVMAKGPVEIWLLDLLKMQMSSLHNIIRSAFY 1675
Query: 1729 AYEEKPRELWIF--DFPAQVALTSSQIWWTTDVGIAFSRLEEGYETALKDFHKKQISQLN 1786
+ +L F FPAQV L Q+ WT D A ++ + ++ ++K + LN
Sbjct: 1676 QISDSGFQLLPFLSHFPAQVGLLGIQMLWTHDSEEALRNAKDDRKI-MQVTNQKFLDILN 1734
Query: 1787 TLITLLLGELPPGDRQKIMTICTIDVHARDVVAKLISQKQVVVSPQAFTWLSQLRHRWED 1846
TLI+ +L DR K T+ TI VH RD+ L+ K + SP F WL Q R +++
Sbjct: 1735 TLISQTTHDLSKFDRVKFETLITIHVHQRDIFDDLV--KMHIKSPTDFEWLKQSRFYFKE 1792
Query: 1847 TQKHCFVNICDAQFQYFYEYLGNSPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGK 1906
V+I D F Y E+LG + RLVITPLTDRCYITL Q+L + M GAPAGPAGTGK
Sbjct: 1793 DLDQTVVSITDVDFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGK 1852
Query: 1907 TETTKDLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGAWGCFDEFNRISVEVLSVVA 1966
TETTKD+GR LG V VFNCS+QMD++ +G I+KGL Q+G+WGCFDEFNRI + VLSV A
Sbjct: 1853 TETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAA 1912
Query: 1967 VQVKMIHDAIRNRKKRFVFL-GEAITLKPSVGIFITMNPGYAGRTELPENLKALFRPCAM 2025
Q+ ++ A + RKK+F+F G+ + L P GIF+TMNPGYAGR ELPENLK FR AM
Sbjct: 1913 QQIYIVLTARKERKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAM 1972
Query: 2026 VAPDIELICEILLVAEGFVDARALARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAG 2085
+ PD ++I + L + GF++ LA+KF LY LC+E L+KQ HYD+GLR I SVL G
Sbjct: 1973 MVPDRQIIMRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLG 2032
Query: 2086 SLKRGDKNRPEDQVLMRALRDFNMPKIVTDDIPVFLGLVGDLFPALDVPRRRKLHFEQMV 2145
S KR E ++MR LRD N+ K+V +D P+FL L+ DLFP L + + V
Sbjct: 2033 SQKRARPEDSELSIVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQNAV 2092
Query: 2146 RQSTLELRLQPEESFILKVVQLEELLAVRHSVFVVGNAGTGKSKILRTLNRTYVNMKQKP 2205
L + LK+VQL E VRH + +G +G+GK+ ++ L + +
Sbjct: 2093 AHQVQIEGLINHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKAQTECGRPH 2152
Query: 2206 VWNDLNPKAVTTDELFGFIHHATREWKDGKIVYSYFIGLFSSILREQANLKHDGPKWIVL 2265
+NPKA+T ++FG + AT +W D G+FS++ R+ K +++L
Sbjct: 2153 REMRMNPKAITAPQMFGRLDTATNDWTD---------GIFSTLWRKTLKAKKGENIFLIL 2203
Query: 2266 DGDIDPMWIESLNTVMDDNKVLTLASNERIALTPFMRLLFEIHHLRSATPATVSRAGILY 2325
DG +D +WIE+LN+V+DDNK LTLA+ +RI + P +LLFE+H++ +A+PATVSR G++Y
Sbjct: 2204 DGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPSCKLLFEVHNIENASPATVSRMGMVY 2263
Query: 2326 VNPQDLGWNPYVASWIDRRRHQSEKANLTILFDKYVPACLDKLRTSFKTITSIPESSLVQ 2385
++ L W P + +W+ +R Q LT L++K ++ + + E + +
Sbjct: 2264 ISSSALSWRPILQAWLKKRTAQEAAVFLT-LYEKVFEDTYTYMKLNLNPKMQLLECNYIV 2322
Query: 2386 TLCVLLECLLTPENVPSDSPKEVYEVYFVFACIWAFGGTLLQDQISDYQADFSRWWQKEM 2445
LLE L+ + S E FVF +W+ G L + +A F R + ++
Sbjct: 2323 QSLNLLEGLIPSKEEGGVSCVEHLHKLFVFGLMWSLGALLELESREKLEA-FLRQHESKL 2381
Query: 2446 KAVKFP--SQGTIFDYYV------DHKTKKLLPWADKIAQFTMDPDVPLQTVLVHTTETA 2497
+ P S T++++YV +H KKL P+ + D ++LV +
Sbjct: 2382 DLPEIPKGSNQTMYEFYVTDYGDWEHWNKKLQPY-----YYPTDSIPEYSSILVPNVDNI 2436
Query: 2498 RLRYFMELLLEKGKPLMLVGNAGVGKTVFVGDTLASLSEDYIVSR-VPFNYYTTSTALQK 2556
R + ++ + ++ K ++L G G KTV V L + +S+ + F+ T Q+
Sbjct: 2437 RTNFLIDTIAKQHKAVLLTGEQGTAKTVMVKAYLKKYDPEVQLSKSLNFSSATEPMMFQR 2496
Query: 2557 ILEKPLEKKAGHNYGPGGNKKLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYDRQK 2616
+E ++K+ G YGP G +K+ FIDD+NMP ++ +G + ++RQ ++ Y K
Sbjct: 2497 TIESYVDKRIGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDK 2556
Query: 2617 V-MLKEIHNCQYVACM-NPMVGSFTINPRLQRHFTVFAFNFPSLDALNTIYGQIFSFHFQ 2674
I + Q +A M +P G I RL+R FTVF PS +++ I+G I +F
Sbjct: 2557 PGDFTTIVDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNASIDKIFGIIGCGYFD 2616
Query: 2675 Q-QAFAPSILRSGPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGIL-FASP 2732
++F P I L+ Q LPT KFHYIFNLRDLS ++QG+L +
Sbjct: 2617 PCRSFKPQICEMIVNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAE 2676
Query: 2733 ECLKGPLDLIHLWLHESARVYGDKLIDKKDCDLFQRRMLETAYKYFEGIDSHMLLQQPLI 2792
EC P L+ L+ HE +RV D+ I +D F + + + +L +P
Sbjct: 2677 ECASIP-TLLSLFKHECSRVIADRFITPEDEQWFNAHLTRAVEENIGSDAASCILPEPYF 2735
Query: 2793 YCHF-------ADRGKDPHYMPVKDWEVLKT--ILTETLDNY----NEL--NAAMHLVLF 2837
D +D + K +E++ + L E L Y NE+ ++ LV F
Sbjct: 2736 VDFLREMPEPTGDEPEDSVFEVPKIYELMPSFDFLAEKLQFYQRQFNEIIRGTSLDLVFF 2795
Query: 2838 EDAMQHVCRISRILRTPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYGIQEL 2897
+DAM H+ +ISRI+RT G ALLVGVGGSGKQSLSRLA+++ G ++FQITLT Y + L
Sbjct: 2796 KDAMTHLIKISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVTNL 2855
Query: 2898 RVDLANLYIRTGAKNMPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDKIISG 2957
DL LY GA F+ TD+++ DE+FL +N+LL+SGEI +LF+ +++D+I G
Sbjct: 2856 TDDLKALYKVAGADGKGITFIFTDSEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQG 2915
Query: 2958 IHNEV--HALGMVDSRENCWKFFMARVRLQLKIILCFSPVGRTLRVRARKFPAIVNCTAI 3015
+ + + + +N +++F++R R L ++LCFSPVG R R+ KFP +++ +
Sbjct: 2916 LISVMKRELPRHPPTFDNLYEYFISRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTM 2975
Query: 3016 DWFHAWPQEALVSVSRRFIEETKGI-EPVHKDSISLFMAHVHTTVNEMSTRYYQNERRHN 3074
DWF WP+EAL++V+ F+ + + K + M H V+E Y+Q RR
Sbjct: 2976 DWFSRWPREALIAVASYFLSDYNIVCSSEIKRQVVETMGLFHDMVSESCESYFQRYRRRA 3035
Query: 3075 YTTPKSFLEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLASQEAEL 3134
+ TPKS+L I+ +KN+ +K ++E+ ER+ G+ KL + V L LA +E EL
Sbjct: 3036 HVTPKSYLSFINGYKNIYAEKVKFINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKEL 3095
Query: 3135 QLRNHDAEALITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQRECEADLLKAEPAL 3194
+ + A+ ++ ++ + + ++ K + K I E+ ++ + E+ L A+PAL
Sbjct: 3096 AVASIKADEVLAEVTVSAQASAKIKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPAL 3155
Query: 3195 VAATAALNTLNRVNLSELKAFPNPPIAVTNVTAAVMVLLAPR-GRVPKDRSWKAAKVFMG 3253
A AALNT+ +++ ++ PP + + V++L + V D K G
Sbjct: 3156 EEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKSCCKPSWG 3215
Query: 3254 K------VDDFLQALINYDKEHIPENCLKVVNEHYLKDPEFNPNLIRTKSFAAAGLCAWV 3307
+ FL +L + K+ I E ++++ ++ D ++ + AGL +W
Sbjct: 3216 ESLKLMSATGFLWSLQQFPKDTINEETVELLQPYFNMD-DYTFESAKKVCGNVAGLLSWT 3274
Query: 3308 INIIKFYEVYCDVEPKRQALAQANLELAAATEKLEAIRKKLVDLDRNLSRLTASFEKATA 3367
+ + FY + +V P + LA+ LA A +L + L + L ++ A F+ A
Sbjct: 3275 LAMAIFYGINREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMN 3334
Query: 3368 EKVRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLLTAAFVSY 3427
EK+ + + K ++ A+ L+ L +KIRW Q K F+AQ L GD+LL F+SY
Sbjct: 3335 EKMDLLNDADTCRKKMQAASTLIDGLSGEKIRWTQQSKEFKAQINRLVGDILLCTGFLSY 3394
Query: 3428 VGPFTRQYRQELVHCKWVPFLQQKVSIPLTEGLDLISMLTDDATIAAWNNEGLPSDRMST 3487
+GPF + +R L+ +W L+ + IP TE L+LISML D TI W +GLP D +S
Sbjct: 3395 LGPFNQIFRNYLLKDQWEMELRAR-KIPFTENLNLISMLVDPPTIGEWGLQGLPGDDLSI 3453
Query: 3488 ENAAILTHCERWPLVIDPQQQGIKWIKNK-YGMDLKVTHLGQKGFLNAIETALAFGDVIL 3546
+N I+T R+PL+IDPQ QG WIK+K DL+VT L K F +E +L+ G +L
Sbjct: 3454 QNGIIVTKATRYPLLIDPQTQGKTWIKSKEKENDLQVTSLNHKYFRTHLEDSLSLGRPLL 3513
Query: 3547 IENLEETIDPVLDPLLGRNTIKKGK--YIRIGDKECEFNKNFRLILHTKLANPHYKPELQ 3604
IE++ E +DP LD +L +N IK G +++GDKEC+ F+L + TKL NP + PE+
Sbjct: 3514 IEDIHEELDPALDNVLEKNFIKSGTTFKVKVGDKECDIMDTFKLYITTKLPNPAFTPEIN 3573
Query: 3605 AQTTLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLEDDLLLRL 3664
A+T++++FTVT GLE QLL V+ E+ +LE ++ L + K ++K LED+LL +L
Sbjct: 3574 AKTSVIDFTVTMKGLENQLLRRVILTEKQELEAERVKLLEDVTFNKRKMKELEDNLLYKL 3633
Query: 3665 SAAEGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENERKINEARECYRPVAARASLLYF 3724
SA +GS +DD L+ L TK T AE+ K+ A E E KIN A+E +RP A R S+LYF
Sbjct: 3634 SATKGSLVDDESLIGVLRTTKQTAAEVSEKLHVAAETEIKINAAQEEFRPAATRGSILYF 3693
Query: 3725 VINDLQKINPLYQFSLKAFNVLFHRAIEQADKVEDMQGRISILMESITHAVFLYTSQALF 3784
+I ++ +N +YQ SL F LF +++ +++K Q RI+ ++E +T+ VF Y+ + L+
Sbjct: 3694 LITEMSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQKRITNIIEYLTYEVFTYSVRGLY 3753
Query: 3785 EKDKLTFLSQMAFQILLRKKEIDPLELDFLLR----FTVEHTHLSPVDFLTSQSWSAIKA 3840
E K F+ M +I L++ + E L++ ++ P ++ +W +
Sbjct: 3754 ENHKFLFVLLMTLKIDLQRGTVKHREFQALIKGGAALDLKACPPKPYRWILDMTWLNLVE 3813
Query: 3841 IAVMEEFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKK-SLIQKLILLRAMRPDRM 3899
++ + +F I + + K W+ W + + PE+E +P + KL+L+R+ PDR
Sbjct: 3814 LSKLPQFAEIMNQISRNEKGWKSWFDKDAPEEEIIPDGYNDSLDTCHKLLLIRSWCPDRT 3873
Query: 3900 TYALRNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEILGKRLGF 3959
+ R ++ + L KY E L+L K +EES TP+ LS G D ++ L K+L
Sbjct: 3874 VFQARKYIADSLEEKYTEPVILNLEKTWEESDTRTPLICFLSMGSDPTNQIDALAKKLKL 3933
Query: 3960 TIDSGKFHNVSLGQGQETVAEVALEKASKGGHWVILQNVHLVAKWLGTLEKLLERF--SQ 4017
+ +S+GQGQE A ++ + + G WV+LQN HL L +E+LLE ++
Sbjct: 3934 -----ECRTISMGQGQEVHARKLIQMSMQQGGWVLLQNCHL---GLEFMEELLETLITTE 3985
Query: 4018 GSHRDYRVFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHAALYNFDQDTLEI 4077
S +RV+++ E P + P LL+ S+K TNEPP G+ A L +QD L+I
Sbjct: 3986 ASDDSFRVWITTE----PHDR-FPITLLQTSLKFTNEPPQGVRAGLKRTFAGINQDLLDI 4040
Query: 4078 CSKEQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICASVLYNYL---EAN 4134
S +K +L+++ + H+ V R +FGP GW+ Y FN D + + N+L +
Sbjct: 4041 -SNLPMWKPMLYTVAFLHSTVQERRKFGPLGWNIPYEFNSADFSASVQFIQNHLDECDIK 4099
Query: 4135 SKVPWEDLRYLFGEIMYGGHITDDWDRKLCRVYLEEFMNPSLTEDELMLAPGFAAPPYLD 4194
V W +RY+ GE+ YGG +TDD+D++L + + + + E G+ P
Sbjct: 4100 KGVSWNTVRYMIGEVQYGGRVTDDFDKRLLNCFARVWFSEKMFEPSFCFYTGYKIPLCKT 4159
Query: 4195 YAGYHQYIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALSGDELGQST 4254
Y +YI+ + ++P ++GLHPNA+I + + T++ + T+ +QP+ SG +G++
Sbjct: 4160 LDQYFEYIQSLPSLDNPEVFGLHPNADITYQSNTASAVLETITNIQPKE--SGGGVGETR 4217
Query: 4255 EEKVKNVLDDILEKLPEEFNMAEI---MQKNSNRSPYVLVCFQECERMNILIREIRISLE 4311
E V + +D+L KLP ++ E+ + K + + + QE +RM +I +R SL
Sbjct: 4218 EAIVYRLSEDMLSKLPPDYIPHEVKSRLIKMGHLNSMNIFLRQEIDRMQRVISILRSSLS 4277
Query: 4312 QLDLSLKGELALSPAVEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRELDTW 4371
L L+++G + +S + + +P W ++++ S+ L WF +LL R + TW
Sbjct: 4278 DLKLAIEGTIIMSENLRDALDNMYDARIPQLWKRVSWDSS-TLGFWFTELLERNAQFSTW 4336
Query: 4372 TQDLTLPAVVWLSGFFNPQSFLTAIMQTMARKNE-WPLDKTRLTADVTKKTKEDYGHPPR 4430
+ P V W++GFFNPQ FLTA+ Q + R ++ W LD + +V ++TKE+ PP
Sbjct: 4337 IFE-GRPNVFWMTGFFNPQGFLTAMRQEVTRAHKGWALDTVTIHNEVLRQTKEEITSPPG 4395
Query: 4431 EGAYLHGLFMEGARWDTQAGTIVEARLKELACPMPVIFAKATPVDRQETKQTYECPVYRT 4490
EG Y++GL+M+GA WD + G ++E+ K L +PV+ A + + Y CP+Y+
Sbjct: 4396 EGVYIYGLYMDGAAWDRRNGKLMESTPKVLFTQLPVLHIFAINSTAPKDPKLYVCPIYKK 4455
Query: 4491 KLRGP-SYIWTFRLKSEEKTAKWVLAGVALLLE 4522
R ++I L++ W+L GVALL +
Sbjct: 4456 PRRTDLTFITVVYLRTVLSPDHWILRGVALLCD 4488
Score = 156 bits (395), Expect = 4e-37
Identities = 156/694 (22%), Positives = 293/694 (42%), Gaps = 41/694 (5%)
Query: 126 LVFISKKITESIGVNDFSQVVLFGELPALS--LGHVSAFLDEILVPVLSNKNNHKSWSCF 183
+ F+ + +I V + LF L A L + L I +P + NN + +
Sbjct: 19 IFFVRCRNDVAINVKTIQEEALFTVLDASKGLLNGIRDMLANIFLPAVLATNNWGALNQS 78
Query: 184 TSQDMEYHI--EVMKKKMYIFRG-KMSRRTLLPIPTVAG-KMDLDQNCSENKPPSNERII 239
+ E HI E + + + G ++S + + T+ E ++
Sbjct: 79 KQGESEKHIFTETINRYLSFLDGARISIEGTVKLKTIDNVNFSKLHTFEEVTAAASNSET 138
Query: 240 LHAIESVVIEWSHQIQEIIERDSVQRLLNGLHLSPQAELDFWMMRRENLSCIYDQLQAPV 299
+H +E V++ W QI++++ R G P EL+ W + I +Q++ P
Sbjct: 139 VHQLEEVLMVWYKQIEQVLIESEQMRKEAG-DSGPLTELEHWKRMSAKFNYIIEQIKGPS 197
Query: 300 VLKMVKILTTKQSSYFPTLKDIFLAVENALLEAQDVELYLRPLRRHIQCLQETEFPQTRI 359
++ +L S +D+ + + E++D YL L + Q L +
Sbjct: 198 CKAVINVLNVAHSKLLKNWRDLDARITDTANESKDNVRYLYTLEKVCQPLYNHDLVSMAH 257
Query: 360 LIAPLFHTICLIWSHSKFYNTPARVIVLLQEFCNLFINQATAYLSPEDLLRGEIEES--- 416
I L + I +I S++YNT R+ L + N + AY++ L +E+
Sbjct: 258 GIQNLINAIRMIHGVSRYYNTSERMTSLFIKVTNQMVTACKAYITDGGLNHVWDQETPVV 317
Query: 417 LEKVQVAVNILKTFKNSFFNYRKKLASYFMGRKLRPWDFQSHLVFCRFDKFLDRLIKIED 476
L+K+Q + + K ++ SF R KL S G K ++ +F +F+ F RL KI +
Sbjct: 318 LKKIQDCIFLFKEYQASFHKTR-KLISESSGEK--SFEVSEMYIFGKFEAFCKRLEKITE 374
Query: 477 IFATTLEFEKLERLEFGGTKGAILNGQVHEMSEELMELCKLFKQSTYDPSDCTNMEFESD 536
+ + L G + M+ + + + K+ YD D EF++D
Sbjct: 375 MITVVQTYSTLSNSTIEG---------IDIMAIKFRNIYQGVKKKQYDILDPRRTEFDTD 425
Query: 537 YVAFKSKTLEFDRRLGTIICEAFFNCNGLEAAFKLLTIFGNFLEKPVVMEIFSLHYSTLV 596
++ F +K + ++ + +F + A +LL F L P + + ++
Sbjct: 426 FLDFMTKINGLEVQIQAFMNSSFGKILSSQQALQLLQRFQK-LNIPCLGLEINHTIERIL 484
Query: 597 HMFNTELDVCKQLYNEHMKQIECGHVVLNKNMPFTSGNMKWAQQVLQRLQMFWSNFASLR 656
+ ELD K+LY+ L +NMP +G + W +Q+ +R+ +
Sbjct: 485 QYYVAELDATKKLYHSQKDD-----PPLARNMPPIAGKILWVRQLYRRIS------EPIN 533
Query: 657 YLF-----LGNPDHALVYQKYVEMTTLLDQFESRIYNEWKSNVDEICEFNLNQPLVKFSA 711
Y F L +PD V ++Y +++ +L +FE + W + ++ + L L
Sbjct: 534 YFFKNSDILSSPDGKAVIRQYNKISYVLVEFEVVYHTAWIREISQL-HYALQATLFVRHP 592
Query: 712 INGLLCVNFDPKLVAVLREVKYLLMLKKQDIPDSALAIFKKRNTILKYIGNLDLLVQGYN 771
G L VNFDPK++ V+RE K ++ + K D+P+ A + K + + L L+Q Y+
Sbjct: 593 ETGKLLVNFDPKILEVVRETKCMIKM-KLDVPEQAKRLLKLESKLKADKLYLQGLLQYYD 651
Query: 772 KLKQTLLEVEYPLIEDELRAIDEQLTAATTWLTW 805
+L Q + V L+ +++ ++ L T LTW
Sbjct: 652 ELCQEVPSVFVNLMTPKMKKVESVLRQGLTVLTW 685
>gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]
Length = 4646
Score = 1365 bits (3534), Expect = 0.0
Identities = 988/3448 (28%), Positives = 1681/3448 (48%), Gaps = 314/3448 (9%)
Query: 1284 KANEELEALEEEMLQMQESTRLFEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNW 1343
KA E LE + +L E +VAL +E++ LKG+W + V ID
Sbjct: 1299 KAKEALELTDTGLLSGSEER--VQVAL----------EELQDLKGVWSELSKVWEQIDQM 1346
Query: 1344 TKTQWRQIHVEQMDVELRRFAKASSITEIWSLNKEVRVWDAYTGLEGTVKDMTASLRAIT 1403
+ W + ++ L + ++ S +R + +Y ++ +K +
Sbjct: 1347 KEQPWVSVQPRKLRQNLDAL-----LNQLKSFPARLRQYASYEFVQRLLKGYMKINMLVI 1401
Query: 1404 ELQSPALRDRHWHQLMKAIGVKFLINEATTLADLLALRLHRVEDDVRRIVDKAVKELGTE 1463
EL+S AL+DRHW QLMK + V ++++E T L + + L + E V+ ++ A E+ E
Sbjct: 1402 ELKSEALKDRHWKQLMKRLHVNWVVSELT-LGQIWDVDLQKNEAIVKDVLLVAQGEMALE 1460
Query: 1464 KVITEISQTWATMKFSYEVHYRTGIPLLKSDEQLFETLEHNQVQLQTLLQSKYVEYFIEQ 1523
+ + +I + W T + V+Y+ L++ + LF ++ + + + S Y + F E
Sbjct: 1461 EFLKQIREVWNTYELDL-VNYQNKCRLIRGWDDLFNKVKEHINSVSAMKLSPYYKVFEED 1519
Query: 1524 VLSWQNKLNIADLVIFTWMEVQRTWSHLESIFVCSEDIRIQLVKDARRFDGVDAEFKELM 1583
LSW++KLN + W++VQR W +LE IF S DI+ L + +RF + EF LM
Sbjct: 1520 ALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHLLPVETQRFQSISTEFLALM 1579
Query: 1584 FKTAKVENVLEATCRPNLYEKLKDLQSRLSLCEKALAEYLETKRIAFPRFYFVSSADLLD 1643
K +K V++ + L+ L L +KAL EYLE +R +FPRFYFV DLL+
Sbjct: 1580 KKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLERERSSFPRFYFVGDEDLLE 1639
Query: 1644 ILSKGAQPKQVTCHLAKLFDSIADLQFEDNQDVSAHRAVGMYSKEKEYVPFQAECECVGH 1703
I+ ++ H K+F ++ + ++ V +G+ S+E E V F+ H
Sbjct: 1640 IIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSV----VLGISSREGEEVMFKTPVSITEH 1695
Query: 1704 --VETWLLQLEQTMQETVRHSITEAIVAYEEKPREL---------WIFDFPAQVALTSSQ 1752
+ WL +E+ M+ T+ + E++ E + WI + AQ+ + S+Q
Sbjct: 1696 PKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYITWIDKYQAQLVVLSAQ 1755
Query: 1753 IWWTTDVGIAFSRLEEGYETA-LKDFHKKQISQLNTLITLLLGELPPGDRQKIMTICTID 1811
I W+ +V A S + G + A L LN L +L E PP R+K+ + T
Sbjct: 1756 IAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQPPLRRRKLEHLITEL 1815
Query: 1812 VHARDVVAKLISQKQVVVSPQAFTWLSQLRHRWE----DTQKHCFVNICDAQFQYFYEYL 1867
VH RDV LI K + + ++F WLSQ+R ++ D + + + +A+F Y +EYL
Sbjct: 1816 VHQRDVTRSLIKSK--IDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQMANAKFNYGFEYL 1873
Query: 1868 GNSPRLVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCS 1927
G +LV TPLTDRCY+T+TQ+L + G+P GPAGTGKTE+ K LG LG V VFNC
Sbjct: 1874 GVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALGHQLGRFVLVFNCD 1933
Query: 1928 EQMDYKSIGNIYKGLVQTGAWGCFDEFNRISVEVLSVVAVQVKMIHDAIRNRKK------ 1981
E D++++G I+ GL Q GAWGCFDEFNR+ +LS V+ QV+ I +A+R
Sbjct: 1934 ETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQEALREHSNPNYDKT 1993
Query: 1982 ----RFVFLGEAITLKPSVGIFITMNPGYAGRTELPENLKALFRPCAMVAPDIELICEIL 2037
L + + + P + IFITMNPGYAGR+ LP+NLK LFR AM PD +LI +++
Sbjct: 1994 SAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLAMTKPDRQLIAQVM 2053
Query: 2038 LVAEGFVDARALARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKR-------- 2089
L ++GF A LA K + + LC E LS Q HYD+GLRA+KSVLV AG++KR
Sbjct: 2054 LYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSAGNVKRERIQKIKR 2113
Query: 2090 -----------GD--KNRPEDQVLMRALRDFNMPKIVTDDIPVFLGLVGDLFPALDVPRR 2136
G+ +N PE ++L++++ + +PK+V +DIP+ L+ D+FP + R
Sbjct: 2114 EKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSLLSDVFPGVQYHRG 2173
Query: 2137 RKLHFEQMVRQSTLELRLQPEES------FILKVVQLEELLAVRHSVFVVGNAGTGKSKI 2190
+ +++ E+ L + ++ KV+QL ++ + H + +VG +G+GKS
Sbjct: 2174 EMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGLMMVGPSGSGKSMA 2233
Query: 2191 LRTLNRTYVNMKQ-KPVWNDLNPKAVTTDELFGFIHHATREWKDGKIVYSYFIGLFSSIL 2249
R L + ++ + V + ++PKA++ D L+G + TREW DG LF+ +L
Sbjct: 2234 WRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDG---------LFTHVL 2284
Query: 2250 R---EQANLKHDGPKWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIALTPFMRLLFE 2306
R + + +WIV DGD+DP W+E+LN+V+DDNK+LTL + ER++L P +R++FE
Sbjct: 2285 RKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVRIMFE 2344
Query: 2307 IHHLRSATPATVSRAGILYVNPQ----DLGWNPYVASW-----------IDRRR-----H 2346
+ L+ AT ATVSR G+++ + D+ +N ++A RRR
Sbjct: 2345 VQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKGKEDE 2404
Query: 2347 QSEKANLTILFDKYVPACLDKLRTSFKTITSIPESSL-VQTLCVL--LECL--------L 2395
E A+ + + + TS +T E + ++ + L L CL
Sbjct: 2405 GEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFSMLHQ 2464
Query: 2396 TPENVPS------DSPKEVYEV------YFVFACIWAFGGTLLQDQISDYQADFSRWWQK 2443
NV D P ++ ++ Y V+A +W+ G D +A+ + ++
Sbjct: 2465 ACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSG----DSRLKMRAELGEYIRR 2520
Query: 2444 EMKAVKFPSQGTI--FDYYVDHKTKKLLPWADKIAQFTMDPD-VPLQTVLVHTTETARLR 2500
+ V P+ I DY V + + PW K+ Q ++ V V+V T +T R
Sbjct: 2521 -ITTVPLPTAPNIPIIDYEVSI-SGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHE 2578
Query: 2501 YFMELLLEKGKPLMLVGNAGVGKTVFVGDTLASLSEDYIVSRVPFNYYTTSTALQKILEK 2560
+ L + KPL+L G G GKT+ + L +L + +V N+ + +T ++L K
Sbjct: 2579 ALLYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVG---LNFSSATTP--ELLLK 2633
Query: 2561 PLEKKAGHNYGPGG--------NKKLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWY 2612
+ + P G K L+ F D++N+P++D YGT + + IRQ +++G +Y
Sbjct: 2634 TFDHYCEYRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFY 2693
Query: 2613 DRQKVMLKEIHNCQYVACMNPMV--GSFTINPRLQRHFTVFAFNFPSLDALNTIYGQIFS 2670
++ Q+V NP G ++ R RH V ++P +L IYG +
Sbjct: 2694 RTSDQTWVKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYG---T 2750
Query: 2671 FHFQQQAFAPSILRSGPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFA 2730
F+ PS+ L A + F+ TM + HYI++ R+++ +GI A
Sbjct: 2751 FNRAMLRLIPSLRTYAEPLTAAMVEFY-TMSQERFTQDTQPHYIYSPREMTRWVRGIFEA 2809
Query: 2731 SPECLKGPLD-LIHLWLHESARVYGDKLIDKKDCDLFQRRMLETAYKYFEGIDSHMLLQQ 2789
P++ LI +W HE+ R++ D+L++ ++ + A K+F ID + +
Sbjct: 2810 LRPLETLPVEGLIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSR 2869
Query: 2790 PLIYCHFADRGKDPHYMPVKDWEVLKTILTETLDNYNELNAAMHLVLFEDAMQHVCRISR 2849
P++Y ++ + Y+PV D E L+ + L + E + LVLF + + HV RI R
Sbjct: 2870 PILYSNWLSKD----YIPV-DQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDR 2924
Query: 2850 ILRTPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYGIQELRVDLANLYIRTG 2909
I R PQG LL+GV G+GK +LSR A++ GL V+QI + Y ++ DL + R+G
Sbjct: 2925 IFRQPQGHLLLIGVSGAGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSG 2984
Query: 2910 AKNMPTVFLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDKIISGIHNEVHALG-MV 2968
KN F++ ++ VLD FL +N LLA+GE+P LF ++ +++ G M+
Sbjct: 2985 CKNEKIAFIMDESNVLDSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLML 3044
Query: 2969 DSRENCWKFFMARVRLQLKIILCFSPVGRTLRVRARKFPAIVNCTAIDWFHAWPQEALVS 3028
DS E +K+F ++V L ++ +P L+ RA PA+ N ++WF W EAL
Sbjct: 3045 DSHEELYKWFTSQVIRNLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQ 3104
Query: 3029 VSRRF-----IEETKGI--------------EPVHKDSISLFMAHVHTTVNEMSTRYYQN 3069
V + F +E+ I P H+++I VH T+++ + R +
Sbjct: 3105 VGKEFTSKMDLEKPNYIVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKR 3164
Query: 3070 ERRHNYTTPKSFLEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLAS 3129
R TP+ +L+ I+ + NL +K++E+ E++ L G++K+K T QV +L+ L
Sbjct: 3165 GGRTMAITPRHYLDFINHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRI 3224
Query: 3130 QEAELQLRNHDAEALITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQRECEADLLK 3189
+ EL+++N A + K+ ++ ++K ++ + ++ Q + KQ + DL K
Sbjct: 3225 KSQELEVKNAAANDKLKKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDK 3284
Query: 3190 AEPALVAATAALNTLNRVNLSELKAFPNPPIAVTNVTAAVMVLLAPRGRVPKDRSWKAAK 3249
EPA++ A A+ ++ + +L E+++ NPP AV ++ +LL WK +
Sbjct: 3285 VEPAVIEAQNAVKSIKKQHLVEVRSMANPPAAVKLALESICLLLGE-----STTDWKQIR 3339
Query: 3250 VFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLKDPEFNPNLIRTKSFAAAGLCAWVIN 3309
+ + ++F+ ++N+ E I + + + ++Y+ +P +N ++ S A + W I
Sbjct: 3340 SIIMR-ENFIPTIVNFSAEEISDAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIA 3398
Query: 3310 IIKFYEVYCDVEPKRQALAQANLELAAATEKLEAIRKKLVDLDRNLSRLTASFEKATAEK 3369
+ + ++ VEP R L + + +K + + + DL+ +++R + +E
Sbjct: 3399 QLNYADMLKRVEPLRNELQKLEDDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEA 3458
Query: 3370 VRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLLTAAFVSYVG 3429
+ ++ + + L+K L A++ RW ++ ++F+ Q T+ GD LL+AAF++Y G
Sbjct: 3459 QAIKADLAAVEAKVNRSTALLKSLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAG 3518
Query: 3430 PFTRQYRQELVHCKWVPFLQQKVSIPLTEGLDLISMLTDDATIAAWNNEGLPSDRMSTEN 3489
F +Q RQ L W LQQ +I + L++ W LP+D + TEN
Sbjct: 3519 YFDQQMRQNLF-TTWSHHLQQ-ANIQFRTDIARTEYLSNADERLRWQASSLPADDLCTEN 3576
Query: 3490 AAILTHCERWPLVIDPQQQGIKWIKNKYGMDLKVTHLG--QKGFLNAIETALAFGDVILI 3547
A +L R+PL+IDP Q ++I N+Y D K+T F +E+AL FG+ +L+
Sbjct: 3577 AIMLKRFNRYPLIIDPSGQATEFIMNEY-KDRKITRTSFLDDAFRKNLESALRFGNPLLV 3635
Query: 3548 ENLEETIDPVLDPLLGRNTIKKGK--YIRIGDKECEFNKNFRLILHTKLANPHYKPELQA 3605
+++E + DPVL+P+L R + G I +GD++ + + +F + L T+ + P+L +
Sbjct: 3636 QDVE-SYDPVLNPVLNREVRRTGGRVLITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCS 3694
Query: 3606 QTTLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLEDDLLLRLS 3665
+ T +NFTVT L++Q L EV+ ERPD+++ + L K Q +F++ L+ LE LL L+
Sbjct: 3695 RVTFVNFTVTRSSLQSQCLNEVLKAERPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALN 3754
Query: 3666 AAEGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENERKINEARECYRPVAARASLLYFV 3725
+G LDD ++ LE K AE+ KV E +++ + Y P++ S +YF
Sbjct: 3755 EVKGRILDDDTIITTLENLKREAAEVTRKVEETDIVMQEVETVSQQYLPLSTACSSIYFT 3814
Query: 3726 INDLQKINPLYQFSLKAFNVLFHRAIEQADK---VEDMQGRISILMESITHAVFLYTSQA 3782
+ L++I+ LYQ+SL+ F ++H + + V D R+SI+ + + F ++
Sbjct: 3815 MESLKQIHFLYQYSLQFFLDIYHNVLYENPNLKGVTDHTQRLSIITKDLFQVAFNRVARG 3874
Query: 3783 LFEKDKLTFLSQMAFQILLRKKEIDP---LELDFLLR---FTVEHTHLSPVDFLTSQSWS 3836
+ +D +TF +A +I L+ +P E LR + + LT +
Sbjct: 3875 MLHQDHITFAMLLA-RIKLKGTVGEPTYDAEFQHFLRGNEIVLSAGSTPRIQGLTVEQAE 3933
Query: 3837 AIKAIAVMEEFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKKS-------LIQKLI 3889
A+ ++ + F+ + V+ +Q+ W++S PE + +P W +++ I +L+
Sbjct: 3934 AVVRLSCLPAFKDLIAKVQAD-EQFGIWLDSSSPE-QTVPYLWSEETPATPIGQAIHRLL 3991
Query: 3890 LLRAMRPDRMTYALRNFVEEKLGAKY--VERTRLDLVKAF-EESSPATPIFFILSPGVDA 3946
L++A RPDR+ FV LG + + LDL E P TP+ PG DA
Sbjct: 3992 LIQAFRPDRLLAMAHMFVSTNLGESFMSIMEQPLDLTHIVGTEVKPNTPVLMCSVPGYDA 4051
Query: 3947 LKDLEILGKRLGFTIDSGKFHNVSLGQGQE-TVAEVALEKASKGGHWVILQNVHLVAKWL 4005
+E L I S +++G + A+ A+ A K G WV+L+NVHL WL
Sbjct: 4052 SGHVEDLAAEQNTQITS-----IAIGSAEGFNQADKAINTAVKSGRWVMLKNVHLAPGWL 4106
Query: 4006 GTLEKLLERFSQGSHRDYRVFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHA 4065
LEK L S H +R+F++ E P +P LL EPP G+ AN+
Sbjct: 4107 MQLEKKLH--SLQPHACFRLFLTMEINPK-----VPVNLLRAGRIFVFEPPPGVKANMLR 4159
Query: 4066 ALYNFDQDTLEICSKEQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICAS 4125
+ IC E + F L +FHA + RLR+ P GWS+ Y F DL
Sbjct: 4160 TFSSI--PVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLGWSKKYEFGESDLRSACD 4217
Query: 4126 VLYNYLE---------ANSKVPWEDLRYLFGEIMYGGHITDDWDRKLCRVYLEEFMNPSL 4176
+ +L+ + K+PW L+ L + +YGG + +++D++L +LE
Sbjct: 4218 TVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEFDQRLLNTFLERLFTTRS 4277
Query: 4177 TEDELMLA------PGFAAPPYLDYAGYHQYIEEMLPPESPALYGLHPNAEIEFLTVTSN 4230
+ E LA P + + Q++E + ++P+ GL NAE LT
Sbjct: 4278 FDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSWLGLPNNAERVLLTTQGV 4337
Query: 4231 TLFRTLLEMQPRNALSGDELGQSTEEK-----------------VKNVLDDILEKLPEEF 4273
+ +L+MQ D+L + EK + + L +P+
Sbjct: 4338 DMISKMLKMQMLE--DEDDLAYAETEKKTRTDSTSDGRPAWMRTLHTTASNWLHLIPQTL 4395
Query: 4274 NMAEIMQKNSNRSPYVLVCFQECERMNILIREIRISLEQLDLSLKGELALSPAVEAQQFA 4333
+ + +N + P +E + L++++R L + +G+ + +
Sbjct: 4396 SHLKRTVENI-KDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEGKKKQTNYLRTLINE 4454
Query: 4334 LSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRELDTWTQDLTLPAV-----------VW 4382
L +P +WS P+ + QW +D R ++L Q+++L A V
Sbjct: 4455 LVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQL----QNISLAAASGGAKELKNIHVC 4510
Query: 4383 LSGFFNPQSFLTAIMQTMARKNEWPLDKTRLTADVTKKTKEDYGHPPREGAYLH------ 4436
L G F P++++TA Q +A+ N W L++ L +VT +GA L
Sbjct: 4511 LGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTS----------QGATLDACSFGV 4560
Query: 4437 -GLFMEGARWDTQAGTIVEARLKELACPMPVI-FAKATPVDRQETKQTYECPVYRTKLRG 4494
GL ++GA + ++ A A P+ + + K T +++ + T PVY R
Sbjct: 4561 TGLKLQGATCNNNKLSLSNA--ISTALPLTQLRWVKQTNTEKKASVVT--LPVYLNFTRA 4616
Query: 4495 PSYIWT--FRLKSEEKTAKWVLAGVALL 4520
I+T F + ++E + GVA+L
Sbjct: 4617 -DLIFTVDFEIATKEDPRSFYERGVAVL 4643
>gi|122937398 dynein, cytoplasmic 2, heavy chain 1 [Homo sapiens]
Length = 4314
Score = 1186 bits (3067), Expect = 0.0
Identities = 901/3214 (28%), Positives = 1514/3214 (47%), Gaps = 215/3214 (6%)
Query: 1414 HWHQLMKAIGVKFLINEATTLADLLALRLHRVED-------DVRRIVDKAVKELGTEKVI 1466
HW L + +G+ T+L LL L RV D D++ + +A E+ + +
Sbjct: 1209 HWLDLFRLLGLP----RGTSLEKLLFGDLLRVADTIVAKAADLKDLNSRAQGEVTIREAL 1264
Query: 1467 TEISQTWATMKFS---YEVHYRTGIPLLKSDEQLFETLEHNQVQLQTLLQSKYVEYFIEQ 1523
E+ F+ YE + L+K + + + N+ LQ+L S Y + F ++
Sbjct: 1265 RELDLWGVGAVFTLIDYEDSQSRTMKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDK 1324
Query: 1524 VLSWQNKLNIADLVIFTWMEVQRTWSHLESIFVCSEDIRIQLVKDARRFDGVDAEFKELM 1583
V W+ KL D + +QR W +LE IF R L K+ RF+ VD +F+ +M
Sbjct: 1325 VSIWERKLAELDEYLQNLNHIQRKWVYLEPIFG-----RGALPKEQTRFNRVDEDFRSIM 1379
Query: 1584 FKTAKVENVLEATCRPNLYEKLKDLQSRLSLCEKALAEYLETKRIAFPRFYFVSSADLLD 1643
K V T + L + +L C+K+L E+LE KR AFPRFYF+ DLL+
Sbjct: 1380 TDIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLE 1439
Query: 1644 ILSKGAQPKQVTCHLAKLFDSIADLQFEDNQDVSAHRAVGMYSKEKEYVPFQAECECVGH 1703
IL + P + HL KLF I + F++ + M S E E VPF+ + +
Sbjct: 1440 ILGQSTNPSVIQSHLKKLFAGINSVCFDEK----SKHITAMKSLEGEVVPFKNKVPLSNN 1495
Query: 1704 VETWLLQLEQTMQETVRHSITEAIVAYEEKPRELWIFDFPAQVALTSSQIWWTTDVGIAF 1763
VETWL L M++T+ + E + + FP+Q+ + QI +T DV
Sbjct: 1496 VETWLNDLALEMKKTLEQLLKECVTTGRSSQGAVDPSLFPSQILCLAEQIKFTEDV---- 1551
Query: 1764 SRLEEGYETALKDFHKKQI-----SQLNTLITLLLGELPPGDRQ------KIMTICTIDV 1812
E A+KD QI ++L + PG+ + K+ + +
Sbjct: 1552 -------ENAIKDHSLHQIETQLVNKLEQYTNIDTSSEDPGNTESGILELKLKALILDII 1604
Query: 1813 HARDVVAKLISQKQVVVSPQAFTWLSQLRHRWEDTQKHCFVNICDAQFQYFYEYLGNSPR 1872
H DVV K ++Q QV + + + W QLR + + C V + D++FQY YEY GN+ +
Sbjct: 1605 HNIDVV-KQLNQIQVHTT-EDWAWKKQLRF-YMKSDHTCCVQMVDSEFQYTYEYQGNASK 1661
Query: 1873 LVITPLTDRCYITLTQSLHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDY 1932
LV TPLTD+CY+TLTQ++ + + G P GPAGTGKTE+ K LG LG V VFNC E +D
Sbjct: 1662 LVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDV 1721
Query: 1933 KSIGNIYKGLVQTGAWGCFDEFNRISVEVLSVVAVQVKMIHDAIRNRKKRFVFLGEAITL 1992
KS+G I+ GLV+ GAWGCFDEFNR+ VLS V++Q++ I DA++N + LG+ + +
Sbjct: 1722 KSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALKNHRTVCELLGKEVEV 1781
Query: 1993 KPSVGIFITMNP---GYAGRTELPENLKALFRPCAMVAPDIELICEILLVAEGFVDARAL 2049
+ GIFITMNP GY GR +LP+NLK LFRP AM PD ELI E++L +EGF DA+ L
Sbjct: 1782 NSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIAEVILYSEGFKDAKVL 1841
Query: 2050 ARKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKR------GDKNRPEDQVLMRA 2103
+RK + ++ L +ELL+ Q HYDWGLRA+K+VL +G+L R +N E ++++A
Sbjct: 1842 SRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLNKSGTTQNANESHIVVQA 1901
Query: 2104 LRDFNMPKIVTDDIPVFLGLVGDLFPALDVPRRRKLHFEQMVRQSTLELRLQPEESFILK 2163
LR M K D F L+ D+FP +++ ++Q E + + I K
Sbjct: 1902 LRLNTMSKFTFTDCTRFDALIKDVFPGIELKEVEYDELSAALKQVFEEANYEIIPNQIKK 1961
Query: 2164 VVQLEELLAVRHSVFVVGNAGTGKSKILRTLNRTYVNMKQKPVWNDLNPKAVTTDELFGF 2223
++L E L R V +VG +G GKS + R L + +NPKA+ +L G
Sbjct: 1962 ALELYEQLCQRMGVVIVGPSGAGKSTLWRMLRAALCKTGKVVKQYTMNPKAMPRYQLLGH 2021
Query: 2224 IHHATREWKDGKIVYSYFIGLFSSILREQANLKHDGPKWIVLDGDIDPMWIESLNTVMDD 2283
I TREW DG + S R+ D WI+ DGDIDP WIESLN+V+DD
Sbjct: 2022 IDMDTREWSDGVLTNS---------ARQVVREPQDVSSWIICDGDIDPEWIESLNSVLDD 2072
Query: 2284 NKVLTLASNERIALTPFMRLLFEIHHLRSATPATVSRAGILYVNPQDLGWNPYVASWIDR 2343
N++LT+ S ERI P + +FE H L A+PAT+SR G+++++ ++ N + SW+ R
Sbjct: 2073 NRLLTMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSWL-R 2131
Query: 2344 RRHQSEKANLTILFDKYVPACLDKLRTSFKTITSIPESSLVQTLCVLLECLLTPENVPSD 2403
+ + NL Y L + K + E+SLV T+ L L +
Sbjct: 2132 NQPAEYRNNLENWIGDYFEKALQWV---LKQNDYVVETSLVGTVMNGLSHLHGCRDHDE- 2187
Query: 2404 SPKEVYEVYFVFACIWAFGGTLLQDQISDYQADFSRWWQKEMKAVKFPSQGTIFDYYVDH 2463
F+ I GG L ++ + W ++ P D Y D
Sbjct: 2188 ---------FIINLIRGLGGNLNMKSRLEFTKEVFHWARESPPDFHKP-----MDTYYDS 2233
Query: 2464 KTKKLLPWADKIAQFTMDPDVP--LQTVLVHTTETAR-LRYFMELLLEKGK-PLMLVGNA 2519
+L + K + D L ++ T + R L YF L K P +LVG
Sbjct: 2234 TRGRLATYVLKKPEDLTADDFSNGLTLPVIQTPDMQRGLDYFKPWLSSDTKQPFILVGPE 2293
Query: 2520 GVGKTVFVGDTLASLSEDYIVSRVPFNYYTTSTALQKILEKP---LEKKAGHNYGPGGNK 2576
G GK + + + L I + V + TTS L + L + + G Y P +
Sbjct: 2294 GCGKGMLLRYAFSQLRSTQIAT-VHCSAQTTSRHLLQKLSQTCMVISTNTGRVYRPKDCE 2352
Query: 2577 KLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYDRQKVMLKEIHNCQYVACMNP--M 2634
+L+ ++ D+N+P++D +GT ++Q + Y +YD + + + N Q VA M+
Sbjct: 2353 RLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYD-ENLEWVGLENIQIVASMSAGGR 2411
Query: 2635 VGSFTINPRLQRHFTVFAFNFPSLDALNTIYGQIFSFHFQQQAFAPSILRSGP---TLIQ 2691
+G + R + + ++P + L TIYG + SI S L
Sbjct: 2412 LGRHKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPVLHKNLKNHSIWGSSSKIYLLAG 2471
Query: 2692 ATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFASPE--CLKGPLD-LIHLWLHE 2748
+ + ++ + F HY F L+ G+ E PLD ++ + +E
Sbjct: 2472 SMVQVYEQVRAKFTVDDYS-HYFFTPCILTQWVLGLFRYDLEGGSSNHPLDYVLEIVAYE 2530
Query: 2749 SARVYGDKLIDKKDCDLFQRRMLETAYKYFEGIDSHMLLQQPLIYCHFADRGK------- 2801
+ R++ DK++ K+ LF +L + ++ G D + A
Sbjct: 2531 ARRLFRDKIVGAKELHLFD-IILTSVFQGDWGSDILDNMSDSFYVTWGARHNSGARAAPG 2589
Query: 2802 ---DPHYMPVKDWEV--LKTILTETLDNYNELNAAMHLVLFEDAMQHVCRISRILRTPQG 2856
PH P+ LK ++ + L +Y N + ++LF + ++++ RI R+L P G
Sbjct: 2590 QPLPPHGKPLGKLNSTDLKDVIKKGLIHYGRDNQNLDILLFHEVLEYMSRIDRVLSFPGG 2649
Query: 2857 CALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYGIQELRVDLANLYIRTGAKNMPTV 2916
LL G G G+++++ L +++ G +F ++ GY +++ + DL ++ G + V
Sbjct: 2650 SLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRGYELKQFKNDLKHVLQLAGIEAQQVV 2709
Query: 2917 FLLTDAQVLDESFLVLINDLLASGEIPDLFSDEDVDKIISGIHNEVHALGMVDSRENCWK 2976
LL D Q + +FL +IN LL+SGE+P L++ E+++ ++ + ++ G +
Sbjct: 2710 LLLEDYQFVHPTFLEMINSLLSSGEVPGLYTLEELEPLLLPLKDQASQDGFFGP---VFN 2766
Query: 2977 FFMARVRLQLKIILCFSPVGRTLRVRARKFPAIVNCTAIDWFHAWPQEALVSVSRRFIEE 3036
+F R++ L I+L + PA+ + W W ++ + E
Sbjct: 2767 YFTYRIQQNLHIVLIMDSANSNFMINCESNPALHKKCQVLWMEGWSNSSMKKIPEMLFSE 2826
Query: 3037 TKGIEPVH---------KDSISLFMAHVHTTVNEMSTRYYQNERRHNYTTPKSFLEQISL 3087
T G E + K+S+ ++E Y TP ++ + +
Sbjct: 2827 TGGGEKYNDKKRKEEKKKNSVDPDFLKSFLLIHESCKAY--------GATPSRYMTFLHV 2878
Query: 3088 FKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLASQEAELQLRNHDAEALITK 3147
+ + K+ E+ +++ L G+ KL + V +L + Q L+ + +A+A +
Sbjct: 2879 YSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQM 2938
Query: 3148 IGLQTEKVSREKTIADAEERKVTAIQTEVFQKQRECEADLLKAEPALVAATAALNTLNRV 3207
I + + S +KT + + ++ ++ +++ + + +L + +P + A A+ +
Sbjct: 2939 ITVSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPE 2998
Query: 3208 NLSELKAFPNPPIAVTNVTAAVMVLLAPRGRVPKDRSWKAAKVFMGKVDDFLQALINYDK 3267
+LSE+++ PP + ++ V+ L+ D SW + K F+ K + + +D
Sbjct: 2999 SLSEIRSLRMPPDVIRDILEGVLRLMG-----IFDTSWVSMKSFLAK-RGVREDIATFDA 3052
Query: 3268 EHIPENCLKVVNEHYLKDP-EFNPNLIRTKSFAAAGLCAWVINIIKFYEVYCDVEPKRQA 3326
+I + + V E K+ F+P + S AAA L AWV I++ V + P
Sbjct: 3053 RNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETE 3112
Query: 3327 LAQANLELAAATEKLEAIRKKLVDLDRNLSRLTASFEKATAEKVRCQEEVNQTNKTIKLA 3386
A L ++ + + L + + +S L F+ T+E + + EV++ +TIK A
Sbjct: 3113 QAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAA 3172
Query: 3387 NRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLLTAAFVSYVGPFTRQYRQELVHCKWVP 3446
L+ +L+ + RW + + TL L AAF++Y+ R+
Sbjct: 3173 EVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAAFITYLSAAPESLRKTC------- 3225
Query: 3447 FLQQKVSIPLTEGLDLISMLTDDATIAAWNNEGLPSDRMSTENAAILTH---CERW---- 3499
L++ E DL L ++ W +EGLPSD +S ENA ++ + W
Sbjct: 3226 -LEEWTKSAGLEKFDLRRFLCTESEQLIWKSEGLPSDDLSIENALVILQIIGLKSWSRVC 3284
Query: 3500 PLVIDPQQQGIKWIKNKY-GMDLKVTHLGQKGFLNAIETALAFGDVILIENLEETIDPVL 3558
P +IDP Q +W+K L+V + F+ A+E A+ FG ++I+ + + ++PVL
Sbjct: 3285 PFLIDPSSQATEWLKTHLKDSRLEVINQQDSNFITALELAVRFGKTLIIQEM-DGVEPVL 3343
Query: 3559 DPLLGRNTIKKGK--YIRIGDKECEFNKNFRLILHTKLANPHYKPELQAQTTLLNFTVTE 3616
PLL R+ + +G ++IGDK ++N+ FRL L T+ NP P+ + T +NFT T
Sbjct: 3344 YPLLRRDLVAQGPRYVVQIGDKIIDYNEEFRLFLSTRNPNPFIPPDAASIVTEVNFTTTR 3403
Query: 3617 DGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLEDDLLLRLSAAEGSFLDDTK 3676
GL QLLA + E+PDLE+ K L + + D KI+L LE+ LL L+ ++G+ L++
Sbjct: 3404 SGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILENKD 3463
Query: 3677 LVERLEATKTTVAEIEHKVIEAKENERKINEARECYRPVAARASLLYFVINDLQKINPLY 3736
L+E L TK + A I+ + E+ + + +++ R+ Y P+A AS +YF+I+DL KIN +Y
Sbjct: 3464 LIESLNQTKASSALIQESLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMY 3523
Query: 3737 QFSLKAFNVLFHRAIEQADKVEDMQGRISILMESITHAVFLYTSQALFEKDKLTFLSQMA 3796
+FSL AF LF RA++ E+ + RI L+ S+ H V+ Y + LF+ D+L F
Sbjct: 3524 RFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYEYICRCLFKADQLMFALHFV 3583
Query: 3797 FQI---LLRKKEIDP---LELDFLLRFTVEHTHLS---PVDFLTSQSWS-AIKAIAVMEE 3846
+ L ++ E D + + +LR + P +SW+ A IA+
Sbjct: 3584 RGMHPELFQENEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQERSWAVATLKIALPSL 3643
Query: 3847 FRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKKSLIQKLILLRAMRPDRMTYALRNF 3906
++ + + A WR + + E+E KK SL Q++++++A+RPDR+ A+ F
Sbjct: 3644 YQTLCFE---DAALWRTYYNNSMCEQEFPSILAKKVSLFQQILVVQALRPDRLQSAMALF 3700
Query: 3907 VEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEILGKRLGFTIDSGK- 3965
+ LG K V L+L + ++E+ PI I+SPG D ++L+ L SG+
Sbjct: 3701 ACKTLGLKEVSPLPLNLKRLYKETLEIEPILIIISPGADPSQELQ----ELANAERSGEC 3756
Query: 3966 FHNVSLGQGQETVAEVALEKASKGGHWVILQNVHLVAKWLGTLEKLLERFSQGSHRDYRV 4025
+H V++GQGQ +A L++ ++ G W+ L+N+HLV WL LEK L +R+
Sbjct: 3757 YHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELNTLQPKD--TFRL 3814
Query: 4026 FMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHAALYNFDQDTLEICSKEQEFK 4085
+++AE P LL++S+KIT E P G+ NL ++ + +I K+ +
Sbjct: 3815 WLTAEVHPN-----FTPILLQSSLKITYESPPGLKKNLMRTYESWTPE--QISKKDNTHR 3867
Query: 4086 S-ILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICASVLYNYLEANSKVPWEDLRY 4144
+ LFSL +FHA R + PQGW++ Y F+ DL +++ + V WE +
Sbjct: 3868 AHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLFDGAKDVQWEFVHG 3927
Query: 4145 LFGEIMYGGHITDDWDRKLCRVYLEEFMNPSLTE------DELMLAPGFAAPPYLDYAGY 4198
L +YGG I + +D ++ + YL++F N S+ + + + + P Y
Sbjct: 3928 LLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVIDVFNQRNKKSIFPYSVSLPQSCSILDY 3987
Query: 4199 HQYIEEMLPPESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALSGDELGQSTEEKV 4258
IE++ + P+ +GL N + S+ + + L + R+ +G + +
Sbjct: 3988 RAVIEKIPEDDKPSFFGLPANIARSSQRMISSQVI-SQLRILGRSITAGSKFDREIWSNE 4046
Query: 4259 KNVLDDILEKLPEEFNMA-EIMQKNSNRSPYVLVCFQECERMNI--LIREIRISLEQLDL 4315
+ + ++ +KL + N+ + + ++R ++ F E+ N L++ + SL L
Sbjct: 4047 LSPVLNLWKKLNQNSNLIHQKVPPPNDRQGSPILSFIILEQFNAIRLVQSVHQSLAALSK 4106
Query: 4316 SLKGELALSPAVEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRELDTWT--- 4372
++G LS V+ AL P W + Q+ L+ R + W
Sbjct: 4107 VIRGTTLLSSEVQKLASALLNQKCPLAWQS-KWEGPEDPLQYLRGLVARALAIQNWVDKA 4165
Query: 4373 -QDLTLPAVVWLSGFFNPQSFLTAIMQTMARKNEWPLDKTRLTADVTKKTKEDYGHPPRE 4431
+ L + LS F+P +FL A+ Q AR +D + A + +E +
Sbjct: 4166 EKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKFVASWKGRLQE-----AKL 4220
Query: 4432 GAYLHGLFMEGARWDTQAGTIVEARLKELACPMPVIFAKATPVDRQETKQTYEC---PVY 4488
+ GL +EG +D + + ++ +P F P D EC PVY
Sbjct: 4221 QIKISGLLLEGCSFDGNQLSENQLDSPSVSSVLP-CFMGWIPQDACGPYSPDECISLPVY 4279
Query: 4489 RTKLRGPSYIWTFRLKSEEKTAKWVLAGVALLLE 4522
T + + +W+ G AL L+
Sbjct: 4280 -TSAERDRVVTNIDVPCGGNQDQWIQCGAALFLK 4312
Score = 42.7 bits (99), Expect = 0.008
Identities = 44/229 (19%), Positives = 98/229 (42%), Gaps = 33/229 (14%)
Query: 626 KNMPFTSGNMKWAQQVLQRLQMFWSNFASLRYLFLGNPDHALVYQKYVEMTTLLDQFESR 685
KN+ ++ W +Q+ ++ L P +Q ++ L +E
Sbjct: 477 KNLSEVVNSIVWVRQLELKVD---DTIKIAEALLSDLPGFRCFHQSAKDLLDQLKLYEQE 533
Query: 686 IYNEWKSNVDE--------ICEFNLNQPLVKFSAINGLLCVNFDPKLVAVLREVKYLLML 737
+++W ++ +C + +++ + +GLL V++ +LV +LREV+ L L
Sbjct: 534 QFDDWSRDIQSGLSDSRSGLC-IEASSRIMELDSNDGLLKVHYSDRLVILLREVRQLSAL 592
Query: 738 ------KKQDIPDSALAIFKKRNTILKYIGNLDLLVQGYNKLKQTLLEVEYPLIEDELRA 791
K Q + + A F K+ ILK + + YN + Q +++ + P++ A
Sbjct: 593 GFVIPAKIQQVANIAQK-FCKQAIILKQVAHF------YNSIDQQMIQSQRPMMLQSALA 645
Query: 792 IDEQL------TAATTWLTWQD--DCWGYIERVRAATSELEHRVERTQK 832
++ + + + +TW + + GYI++++ A L + +K
Sbjct: 646 FEQIIKNSKAGSGGKSQITWDNPKELEGYIQKLQNAAERLATENRKLRK 694
>gi|114155135 dynein, axonemal, heavy chain 9 isoform 1 [Homo sapiens]
Length = 798
Score = 1094 bits (2829), Expect = 0.0
Identities = 519/797 (65%), Positives = 646/797 (81%)
Query: 3726 INDLQKINPLYQFSLKAFNVLFHRAIEQADKVEDMQGRISILMESITHAVFLYTSQALFE 3785
+NDL KI+P+YQFSLKAF+++F +A+E+A E ++ R++ L++SIT +V+ YT + LFE
Sbjct: 1 MNDLSKIHPMYQFSLKAFSIVFQKAVERAAPDESLRERVANLIDSITFSVYQYTIRGLFE 60
Query: 3786 KDKLTFLSQMAFQILLRKKEIDPLELDFLLRFTVEHTHLSPVDFLTSQSWSAIKAIAVME 3845
DKLT+L+Q+ FQILL +E++ +ELDFLLR V+ SPV+FL+ Q+W A+K ++ ME
Sbjct: 61 CDKLTYLAQLTFQILLMNREVNAVELDFLLRSPVQTGTASPVEFLSHQAWGAVKVLSSME 120
Query: 3846 EFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKKSLIQKLILLRAMRPDRMTYALRN 3905
EF +DRD+EGSAK W+K+VESECPEKEKLPQEWK K+ +Q+L +LRAMRPDRMTYALR+
Sbjct: 121 EFSNLDRDIEGSAKSWKKFVESECPEKEKLPQEWKNKTALQRLCMLRAMRPDRMTYALRD 180
Query: 3906 FVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEILGKRLGFTIDSGK 3965
FVEEKLG+KYV LD +FEES PATP+FFILSPGVD LKD+E G++LG+T ++
Sbjct: 181 FVEEKLGSKYVVGRALDFATSFEESGPATPMFFILSPGVDPLKDVESQGRKLGYTFNNQN 240
Query: 3966 FHNVSLGQGQETVAEVALEKASKGGHWVILQNVHLVAKWLGTLEKLLERFSQGSHRDYRV 4025
FHNVSLGQGQE VAE AL+ A+K GHWVILQN+HLVAKWL TLEK LE S+ SH ++RV
Sbjct: 241 FHNVSLGQGQEVVAEAALDLAAKKGHWVILQNIHLVAKWLSTLEKKLEEHSENSHPEFRV 300
Query: 4026 FMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHAALYNFDQDTLEICSKEQEFK 4085
FMSAE AP+P+ HIIPQG+LENSIKITNEPPTGM ANLH AL NF QDTLE+CS+E EFK
Sbjct: 301 FMSAEPAPSPEGHIIPQGILENSIKITNEPPTGMHANLHKALDNFTQDTLEMCSRETEFK 360
Query: 4086 SILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICASVLYNYLEANSKVPWEDLRYL 4145
SILF+LCYFHA VA R +FGPQGW+RSYPFN GDLTI +VLYN+LEAN+KVP++DLRYL
Sbjct: 361 SILFALCYFHAVVAERRKFGPQGWNRSYPFNTGDLTISVNVLYNFLEANAKVPYDDLRYL 420
Query: 4146 FGEIMYGGHITDDWDRKLCRVYLEEFMNPSLTEDELMLAPGFAAPPYLDYAGYHQYIEEM 4205
FGEIMYGGHITDDWDR+LCR YL EF+ P + E EL LAPGF P +DY GYHQYI+
Sbjct: 421 FGEIMYGGHITDDWDRRLCRTYLGEFIRPEMLEGELSLAPGFPLPGNMDYNGYHQYIDAE 480
Query: 4206 LPPESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALSGDELGQSTEEKVKNVLDDI 4265
LPPESP LYGLHPNAEI FLT TS LFRT+LE+QPR++ + D G + EEKVK +L++I
Sbjct: 481 LPPESPYLYGLHPNAEIGFLTQTSEKLFRTVLELQPRDSQARDGAGATREEKVKALLEEI 540
Query: 4266 LEKLPEEFNMAEIMQKNSNRSPYVLVCFQECERMNILIREIRISLEQLDLSLKGELALSP 4325
LE++ +EFN+ E+M K R+PY++V FQEC RMNIL REI+ SL +L+L LKGEL ++
Sbjct: 541 LERVTDEFNIPELMAKVEERTPYIVVAFQECGRMNILTREIQRSLRELELGLKGELTMTS 600
Query: 4326 AVEAQQFALSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRELDTWTQDLTLPAVVWLSG 4385
+E Q AL +D VP++W++ AYPST GLA WF DLL R +EL+ WT D T+P+ VWL+G
Sbjct: 601 HMENLQNALYFDMVPESWARRAYPSTAGLAAWFPDLLNRIKELEAWTGDFTMPSTVWLTG 660
Query: 4386 FFNPQSFLTAIMQTMARKNEWPLDKTRLTADVTKKTKEDYGHPPREGAYLHGLFMEGARW 4445
FFNPQSFLTAIMQ+ ARKNEWPLD+ L D+TKK +E++ PPREGAY+HGLFMEGA W
Sbjct: 661 FFNPQSFLTAIMQSTARKNEWPLDQMALQCDMTKKNREEFRSPPREGAYIHGLFMEGACW 720
Query: 4446 DTQAGTIVEARLKELACPMPVIFAKATPVDRQETKQTYECPVYRTKLRGPSYIWTFRLKS 4505
DTQAG I EA+LK+L PMPV+F KA P D+Q+ + Y CPVY+T RGP+Y+WTF LK+
Sbjct: 721 DTQAGIITEAKLKDLTPPMPVMFIKAIPADKQDCRSVYSCPVYKTSQRGPTYVWTFNLKT 780
Query: 4506 EEKTAKWVLAGVALLLE 4522
+E +KWVLAGVALLL+
Sbjct: 781 KENPSKWVLAGVALLLQ 797
>gi|194440727 dynein heavy chain domain 2 isoform 1 [Homo sapiens]
Length = 3092
Score = 965 bits (2495), Expect = 0.0
Identities = 599/1732 (34%), Positives = 928/1732 (53%), Gaps = 112/1732 (6%)
Query: 1243 EVTLIRKKCILFDAKQAEFRERFRHYAPLGFNAENPYTALDKANEELEALEEEMLQMQES 1302
E+ R+K IL K++ E F +A L + T + + + ++ EE + + +
Sbjct: 604 ELMAKREKLILEIEKESRRMEEFTEFAELE-RMQQYVTDVRQLQKRIQESEEAVQFINKE 662
Query: 1303 TRLFEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTKTQWRQIHVEQMDVELRR 1362
LF+ L +Y ++ + + I+ + ++ ++ +RS W + ++ E M+ ++
Sbjct: 663 EELFKWELTKYPELDKLKVNIEPYQKFFNFVLKWQRSEKRWMDGGFLDLNGESMEADVEE 722
Query: 1363 FAKASSITEIWSLNKEVRVWDAYTGLEGTVKDMTASLRAITE------------LQSPAL 1410
F++ + K ++ + E K A R++ E + +
Sbjct: 723 FSR--------EIFKTLKFFQTKLKKELQEKRKAARKRSLEEEKIEEEPKDNATITMCRM 774
Query: 1411 RDRHWHQLMKAIGVKFLINEATTLADLLALRLHRVEDDVRRIVDKAVKELGTEKVITEIS 1470
R RHW Q+ + +G + TTL +L L L + I A KE EK + +
Sbjct: 775 RARHWKQISEIVGYDLTPDSGTTLRKVLKLNLTPYLEQFEVISAGASKEFSLEKAMNTMI 834
Query: 1471 QTWATMKFSYEVHYRTGIPLLKSDEQLFETLEHNQVQLQTLLQSKYVEYFIEQVLSWQNK 1530
TW + F ++ TG+ +L S +++ L+ ++ QT+ S +++ F ++ +W+++
Sbjct: 835 GTWEDIAFHISLYRDTGVCILSSVDEIQAILDDQIIKTQTMRGSPFIKPFEHEIKAWEDR 894
Query: 1531 LNIADLVIFTWMEVQRTWSHLESIFVCSEDIRIQLVKDARRFDGVDAEFKELMFKTAKVE 1590
L I W++VQ W +LE IF CSEDI Q+ ++ R+F VD ++++M AK
Sbjct: 895 LIRIQETIDEWLKVQAQWLYLEPIF-CSEDIMQQMPEEGRQFQTVDRHWRDIMKFCAKDP 953
Query: 1591 NVLEATCRPNLYEKLKDLQSRLSLCEKALAEYLETKRIAFPRFYFVSSADLLDILSKGAQ 1650
VL AT L EKL++ L K L YLE KR+ FPRF+F+S+ ++L+ILS+
Sbjct: 954 KVLAATSLTGLLEKLQNCNELLEKIMKGLNAYLEKKRLFFPRFFFLSNDEMLEILSETKD 1013
Query: 1651 PKQVTCHLAKLFDSIADLQFEDNQDVSAHRAVGMYSKEKEYVPFQA---ECECVGHVETW 1707
P +V HL K F+ IA L+F N D+ A MYS E E V A G VE W
Sbjct: 1014 PLRVQPHLKKCFEGIAKLEFLPNLDIKA-----MYSSEGERVELIALISTSAARGAVEKW 1068
Query: 1708 LLQLEQTMQETVRHSITEAIVAYEEKPRELWIFDFPAQVALTSSQIWWTTDVGIAFSRLE 1767
L+Q+E M +V I A +AY E R W+ ++P QV L SQ++WT++ S
Sbjct: 1069 LIQVEDLMLRSVHDVIAAARLAYPESARRDWVREWPGQVVLCISQMFWTSETQEVISGGT 1128
Query: 1768 EGYETALKDFHKKQISQLNTLITLLLGELPPGDRQKIMTICTIDVHARDVVAKLISQKQV 1827
EG LK ++K+ +QLN ++ L+ G+L R + + TIDVHARDVV +I K
Sbjct: 1129 EG----LKKYYKELQNQLNEIVELVRGKLSKQTRTTLGALVTIDVHARDVVMDMI--KMG 1182
Query: 1828 VVSPQAFTWLSQLRHRWEDTQKHCFVNICDAQFQYFYEYLGNSPRLVITPLTDRCYITLT 1887
V F WL+QLR+ WE+ ++ V I + +Y YEYLGNSPRLVITPLTDRCY TL
Sbjct: 1183 VSHDTDFLWLAQLRYYWEN--ENARVRIINCNVKYAYEYLGNSPRLVITPLTDRCYRTLI 1240
Query: 1888 QSLHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGA 1947
+ +L + GAP GPAGTGKTETTKDL +AL + VFNCS+ +DY ++G +KGL +GA
Sbjct: 1241 GAFYLNLGGAPEGPAGTGKTETTKDLAKALAVQCVVFNCSDGLDYLAMGKFFKGLASSGA 1300
Query: 1948 WGCFDEFNRISVEVLSVVAVQVKMIHDAIRNRKKRFVFLGEAITLKPSVGIFITMNPGYA 2007
W CFDEFNRI +EVLSVVA Q+ I AI+ + FVF G + L P+ + ITMNPGYA
Sbjct: 1301 WACFDEFNRIELEVLSVVAQQILCIQRAIQQKLVVFVFEGTELKLNPNCFVAITMNPGYA 1360
Query: 2008 GRTELPENLKALFRPCAMVAPDIELICEILLVAEGFVDARALARKFITLYTLCKELLSKQ 2067
GR+ELP+NLK LFR AM+ P+ LI EI L + GF++AR L+ K + Y LC E LS Q
Sbjct: 1361 GRSELPDNLKVLFRTVAMMVPNYALIAEISLYSYGFLNARPLSVKIVMTYRLCSEQLSSQ 1420
Query: 2068 DHYDWGLRAIKSVLVVAGSLKRGDKNRPEDQVLMRALRDFNMPKIVTDDIPVFLGLVGDL 2127
HYD+G+RA+K+VLV AG+LK N ED +L+R+++D N PK ++ DIP+F G+ DL
Sbjct: 1421 FHYDYGMRAVKAVLVAAGNLKLKYPNENEDILLLRSIKDVNEPKFLSHDIPLFNGITSDL 1480
Query: 2128 FPALDVPRRRKLHFEQMVRQSTLELRLQPEESFILKVVQLEELLAVRHSVFVVGNAGTGK 2187
FP + +P F + ++ LQP + F+ K++Q E++ VRH +VG K
Sbjct: 1481 FPGIKLPEADYHEFLECAHEACNVHNLQPVKFFLEKIIQTYEMMIVRHGFMLVGEPFAAK 1540
Query: 2188 SKILRTLNRTYVNM-------KQKPVWNDLNPKAVTTDELFGFIHHATREWKDGKIVYSY 2240
+K+L L T M ++K ++ +NPK++T +LFG + EW D
Sbjct: 1541 TKVLHVLADTLTLMNEHGYGEEEKVIYRTVNPKSITMGQLFGQFDPVSHEWTD------- 1593
Query: 2241 FIGLFSSILREQANLKHDGPKWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIALTPF 2300
G+ ++ RE A + KW+V DG ID +WIES+NTV+DDNK L L S E I ++P
Sbjct: 1594 --GIVANTFREFALSETPDRKWVVFDGPIDTLWIESMNTVLDDNKKLCLMSGEIIQMSPQ 1651
Query: 2301 MRLLFEIHHLRSATPATVSRAGILYVNPQDLGWNPYVASWIDRRR----HQSEKANLTIL 2356
M L+FE L A+PATVSR G++Y+ P LGW P V+SW++ + +A L L
Sbjct: 1652 MSLIFETMDLSQASPATVSRCGMIYLEPSQLGWEPLVSSWLNSLKGPLCEPEYQALLRGL 1711
Query: 2357 FDKYVPACLDKLRTSFKTITSIPESSLVQTLCVLLECLLTP--ENVPSDSPKEVYEVY-- 2412
F +P L++ R + + + + + L +L+ ++ + VP + + +
Sbjct: 1712 FAWLIPPSLNQ-RVELFQLNYLYTTIVSKILKILITFRISNYFKYVPLKTQCTFIKFFLH 1770
Query: 2413 ----FVFACIWAFGGT-----------------LLQDQISDYQADFSRWWQKEMKAVKFP 2451
F+F+ IW+ GG+ L +D + +W F
Sbjct: 1771 QQACFIFSLIWSIGGSCDTDGRRVFDTFIRLIILGKDDENPVPDSVGKW------ECPFD 1824
Query: 2452 SQGTIFDYYVDHKTK-KLLPWADKIAQFTM-DPDVPLQTVLVHTTETARLRYFMELLLEK 2509
+G ++DY + K K + + W + I + D + +Q ++V T +T R + M+L +
Sbjct: 1825 EKGLVYDYMYELKNKGRWVHWNELIKNTNLGDKQIKIQDIIVPTMDTIRYTFLMDLSITY 1884
Query: 2510 GKPLMLVGNAGVGKTVFVGDTLASLSE--DYIVSRVPFNYYTTSTALQKILEKPLEKKAG 2567
KPL+ VG G GK+V+V D L + E Y + + T++ +Q I+ L+K+
Sbjct: 1885 AKPLLFVGPTGTGKSVYVKDKLMNHLEKDQYFPFYINLSARTSANQVQNIIMARLDKRRK 1944
Query: 2568 HNYGPGGNKKLIYFIDDMNMPEVDLYGTVQPHTLIRQHIDYGHWYDRQKVMLKEIHNCQY 2627
+GP KK I FIDDMNMP ++ YG P L+RQ D GHWYD + + + +
Sbjct: 1945 GVFGPPMGKKCIIFIDDMNMPALEKYGAQPPIELLRQFFDCGHWYDLKDTSKITLVDIEL 2004
Query: 2628 VACMNPMVGSFT-INPRLQRHFTVFAFNFPSLDALNTIYGQIFSFHFQQQAFAPSILRSG 2686
+A M P G + PR RHF + + N S + + I+ I +F+ + F P G
Sbjct: 2005 IAAMGPPGGGRNPVTPRCIRHFNICSINSFSDETMVRIFSSIVAFYLRTHEFPPEYFVIG 2064
Query: 2687 PTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGILFASPECLKGPLDLIHLWL 2746
++ T+ ++ + N LPT K HY FNLRD S V +G L + + +I L++
Sbjct: 2065 NQIVNGTMEIYKQSVENLLPTPTKSHYTFNLRDFSRVIRGCLLIERDAVANKHTMIRLFV 2124
Query: 2747 HESARVYGDKLIDKKDCD-LFQ--RRMLETAYK-YFEGIDSHM------LLQQPLIYCHF 2796
HE RV+ D+LI+ D LFQ + +++ +K F I SH+ + ++ L F
Sbjct: 2125 HEVLRVFYDRLINDDDRRWLFQLTKTVIKDHFKESFHSIFSHLRKQNAPVTEEDLRNLMF 2184
Query: 2797 AD------RGKDPHYMPVKDWEVLKTILTETLDNYNELN-AAMHLVLFEDAMQHVCRISR 2849
D G D Y+ + + ++ + LD YN+ + M+LV+F ++H+ RI R
Sbjct: 2185 GDYMNPDLEGDDRVYIEIPNIHHFSDVVDQCLDEYNQTHKTRMNLVIFRYVLEHLSRICR 2244
Query: 2850 ILRTPQGCALLVGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYGIQELRVDL 2901
+L+ G ALLVG+GGSG+QSL+RLA + + +FQ +++ YG+ E R D+
Sbjct: 2245 VLKQSGGNALLVGLGGSGRQSLTRLATSMAKMHIFQPEISKSYGMNEWREDM 2296
Score = 434 bits (1116), Expect = e-120
Identities = 270/798 (33%), Positives = 423/798 (53%), Gaps = 37/798 (4%)
Query: 3748 HRAIEQADKVEDMQGRISILMESITHAVFLYTSQALFEKDKLTFLSQMAFQILLRKKEID 3807
+R ++ K+ ++ R+ L + T+ ++ ++LFEKDKL F + +LL +KEI+
Sbjct: 2306 NRIVDNKSKI--LEKRLRYLNDHFTYNLYCNICRSLFEKDKLLFSFLLCANLLLARKEIE 2363
Query: 3808 PLELDFLLR--FTVEHTHLSP-VDFLTSQSWSAIKAIAVMEEFRGIDRDVEGSAKQWRKW 3864
EL FLL +++ +P +L +SW I + FRG+ + +WR+
Sbjct: 2364 YQELMFLLTGGVSLKSAEKNPDPTWLQDKSWEEICRASEFPAFRGLRQHFCEHIYEWREI 2423
Query: 3865 VESECPEKEKLPQEWKKK-SLIQKLILLRAMRPDRMTYALRNFVEEKLGAKYVERTRLDL 3923
+S+ P K P K + +QK+I+LR +RPD++T A+ N+V +KLG K+VE DL
Sbjct: 2424 YDSKEPHNAKFPAPMDKNLNELQKIIILRCLRPDKITPAITNYVTDKLGKKFVEPPPFDL 2483
Query: 3924 VKAFEESSPATPIFFILSPGVDALKDLEILGKRLGFTIDSGKFHNVSLGQGQETVAEVAL 3983
K++ +S+ P+ F+LSPG D + L L ++ KF +SLGQGQ +A +
Sbjct: 2484 TKSYLDSNCTIPLIFVLSPGADPMASL--LKFANDKSMSGNKFQAISLGQGQGPIAAKMI 2541
Query: 3984 EKASKGGHWVILQNVHLVAKWLGTLEKLLERF-SQGSHRDYRVFMSAESAPTPDEHIIPQ 4042
+ A + G WV LQN HL W+ LEK+ E F S+ + +R+++++ + P
Sbjct: 2542 KAAIEEGTWVCLQNCHLAVSWMPMLEKICEDFTSETCNSSFRLWLTSYPSSK-----FPV 2596
Query: 4043 GLLENSIKITNEPPTGMLANLHAALYN---FDQDTLEIC-SKEQEFKSILFSLCYFHACV 4098
+L+N +K+TNEPPTG+ NL + D + + C KE ++ +LF +C+FHA V
Sbjct: 2597 TILQNGVKMTNEPPTGLRLNLLQSYLTDPVSDPEFFKGCRGKELAWEKLLFGVCFFHALV 2656
Query: 4099 AGRLRFGPQGWSRSYPFNPGDLTICASVLYNYLEANSKVPWEDLRYLFGEIMYGGHITDD 4158
R +FGP GW+ Y FN DL I L ++ +P+E + YL GE YGG +TDD
Sbjct: 2657 QERKKFGPLGWNIPYGFNESDLRISIRQLQLFINEYDTIPFEAISYLTGECNYGGRVTDD 2716
Query: 4159 WDRKLCRVYLEEFMNPSLTED---ELMLAPGFAAPPYLDYAGYHQYIEEMLPPESPALYG 4215
WDR+L L +F N + E+ + + + APP Y Y ++I+++ + P ++G
Sbjct: 2717 WDRRLLLTMLADFYNLYIVENPHYKFSPSGNYFAPPKGTYEDYIEFIKKLPFTQHPEIFG 2776
Query: 4216 LHPNAEIEFLTVTSNTLFRTLLEMQPRNALSGDELGQSTEEKVKNVLDDILEKLPEEFNM 4275
LH N +I + TLF +LL Q + +G ST++ + + DIL KLP +F++
Sbjct: 2777 LHENVDISKDLQQTKTLFESLLLTQGGSKQTG--ASGSTDQILLEITKDILNKLPSDFDI 2834
Query: 4276 AEIMQKNSNRSPYVL--VCFQECERMNILIREIRISLEQLDLSLKGELALSPAVEAQQFA 4333
++K R + V QE ER N LI IR +L L+ ++KG + + A+EA +
Sbjct: 2835 EMALRKYPVRYEESMNTVLVQEMERFNNLIITIRNTLRDLEKAIKGVVVMDSALEALSGS 2894
Query: 4334 LSYDTVPDTWSKLAYPSTYGLAQWFNDLLLRCRELDTWTQDLTLPAVVWLSGFFNPQSFL 4393
L VP+ W+K +YPS L + D L R L W + P V WLSGFF Q+FL
Sbjct: 2895 LLVGKVPEIWAKRSYPSLKPLGSYITDFLARLNFLQDW-YNSGKPCVFWLSGFFFTQAFL 2953
Query: 4394 TAIMQTMARKNEWPLDKTRLTADVTKKTKEDYGHPPREGAYLHGLFMEGARWDTQAGTIV 4453
T MQ ARK P+D +V D P +G Y+HGL+++GARWD ++G +
Sbjct: 2954 TGAMQNYARKYTTPIDLLGYEFEVIPSDTSDTS--PEDGVYIHGLYLDGARWDRESGLLA 3011
Query: 4454 EARLKELACPMPVIFAKATPVDRQETKQTYECPVYRTKLR---------GPSYIWTFRLK 4504
E K L MP+I+ K T R Y CP+Y+T R +++ LK
Sbjct: 3012 EQYPKLLFDLMPIIWIKPTQKSRIIKSDAYVCPLYKTSERKGTLSTTGHSTNFVIAMLLK 3071
Query: 4505 SEEKTAKWVLAGVALLLE 4522
+++ T W+ GVALL +
Sbjct: 3072 TDQPTRHWIKRGVALLCQ 3089
>gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [Homo
sapiens]
Length = 4515
Score = 743 bits (1919), Expect = 0.0
Identities = 519/1875 (27%), Positives = 897/1875 (47%), Gaps = 241/1875 (12%)
Query: 2861 VGVGGSGKQSLSRLAAYLRGLEVFQITLTEGYGIQELRVDLANLYIRTGAKNMPTVFLLT 2920
+G+ G GK++ + LA YL +++++ ++ E + ++I G K PTV ++
Sbjct: 2665 IGIDGCGKKTCATLACYLTDNKLYRVPISHKCAYIEFKEVFKKVFIHAGLKGKPTVLMVP 2724
Query: 2921 DAQVLDESFLVLINDLLASGEIPDLFSDEDVDKIISGIHNEVHALGMVDSRENCWKFFMA 2980
+ + +SFL +N +++SG IPDLF + ++D I I G +D+R++ FF
Sbjct: 2725 NLNIEQDSFLEDLNYIISSGRIPDLFENVELDSIAMKIRYLTEQSGHMDNRQSLLSFFQK 2784
Query: 2981 RVRLQLKIILCFSPVGRTLRVRARKFPAIVNCTAIDWFHAWPQEALVSVSRRFIEETKGI 3040
R+ L I + SP G + R R +P++++ IDW+ WP+EAL+ V+ F++E
Sbjct: 2785 RIYKNLHIFVIMSPEGPSFRQNCRVYPSMISSCTIDWYERWPEEALLIVANSFLKEKVNF 2844
Query: 3041 EPVH--KDSISLFMAHVHTTVNEMSTRYYQNERRHNYTTPKSFLEQISLFKNLLKKKQNE 3098
E K+ ++ +H ++ +++ +Y++ R YTTP S+L+ + F ++L+ ++ E
Sbjct: 2845 ENRENLKEKLAPTCVQIHKSMKDLNRKYFEETGRFYYTTPNSYLQFMETFAHILRAREEE 2904
Query: 3099 VSEKKERLVNGIQKLKTTASQVGDLKARLASQEAELQLRNHDAEALITKIGLQTEKVSRE 3158
+ K++R G+ + + V +++ L +++ + + E L+ K+ ++ V +
Sbjct: 2905 MQTKRDRFHMGLSTILEATTLVTEMQEELLILGPQVEQKTKETETLMEKLRKDSQVVEKV 2964
Query: 3159 KTIADAEERKVTAIQTEVFQKQRECEADLLKAE-PALVAATAALNTLNRVNLSELKAFPN 3217
+ + +E ++ A + + + + A+ LK+ PA A ALN L++ +++EL+ +
Sbjct: 2965 QMLVKQDE-EIVAEEVRIVEDYAQKTANELKSVLPAFDKAIVALNALDKADVAELRVYTR 3023
Query: 3218 PPIAVTNVTAAVMVLLAPRGRVPKDRSWKAAKVFMGKVDDFLQALINYDKEHIPENCLKV 3277
PP V V AV +LL K +W AK+ + + FL+ LIN DK+ IP+ V
Sbjct: 3024 PPFLVLTVMNAVCILLQ------KKPNWATAKLLLSETG-FLKKLINLDKDSIPDKVF-V 3075
Query: 3278 VNEHYLKDPEFNPNLIRTKSFAAAGLCAWVINIIKFYEVYCDVEPKRQALAQANLELAAA 3337
+ + P+FNP+ I S A LC WVI + ++EV V PK+ +A+A L A
Sbjct: 3076 KLKKIVTLPDFNPHKISLVSVACCSLCQWVIALNNYHEVQKVVGPKQIQVAEAQNVLKIA 3135
Query: 3338 TEKLEAIRKKLVDLDRNLSRLTASFEKATAEKVRCQEEVNQTNKTIKLANRLVKELEAKK 3397
++L ++ L ++ +L L A+++ AEK ++ + A+ L+ LE +K
Sbjct: 3136 RQRLAEKQRGLQLVEEHLLFLQAAYKDTVAEKQLLANRKTMASRRFQCASVLLTVLEDEK 3195
Query: 3398 IRWGQSIKSFEAQEKTLCGDVLLTAAFVSYVGPFTRQYRQELVHCKWVPFLQQKVSIPLT 3457
RW ++I + + + + GD+LL+AA + Y G T ++RQ +V+ KW F + I L+
Sbjct: 3196 TRWQETINQIDNKLEGILGDILLSAACIVYSGILTPEFRQLIVN-KWETFCIEN-GISLS 3253
Query: 3458 EGLDLISMLTDDATIAAWNNEGLPSDRMSTENAAILTHCERWPLVIDPQQQGIKWIKNKY 3517
LI ++ I+ W+N+GLP + S ENA ++ + ++WPL+IDP +Q KWI+
Sbjct: 3254 SKFSLIKVMAQKYEISRWHNQGLPHGQYSVENAILIKNGQQWPLLIDPHRQAHKWIRQME 3313
Query: 3518 GMDLKVTHLGQKGFLNAIETALAFGDVILIENLEETIDPVLDPLLGRNTI-KKGKY-IRI 3575
G L+ + + IE A+ G +L++NL ET+ P L +L ++ KKG Y IR+
Sbjct: 3314 GSRLQKLSIEDSNYTKKIENAMKTGGSVLLQNLLETLAPGLKAILKKDIYQKKGHYFIRV 3373
Query: 3576 GDKECEFNKNFRLILHTKLANPHYKPELQAQTTLLNFTVTEDGLEAQLLAEVVSIERPDL 3635
GD E E+N NFRL L T++ NPH+ P + T++NFTVT GL+ QLL+ VV+ E P L
Sbjct: 3374 GDAEFEYNSNFRLYLSTEIDNPHFLPSVYNFVTMINFTVTFQGLQDQLLSTVVTHEVPHL 3433
Query: 3636 EKLKLVLTKHQNDFKIELKYLEDDLLLRLSAAEGSFLDDTKLVERLEATKTTVAEIEHKV 3695
E + L + + I L+ LE+ L L A GS LDD K+V+ L +K T EI ++
Sbjct: 3434 EDQRSKLLESISLDAITLEELEEKTLNLLQKALGSILDDDKIVDTLRKSKMTSNEISKRI 3493
Query: 3696 IEAKENERKINEARECYRPVAARASLLYFVINDLQKINPLYQFSLKAFNVLFHRAIEQAD 3755
K+ E +I R+ Y P+A R +LLYF++ DL +IN +YQFSL F+ +F ++
Sbjct: 3494 EATKKAESEIQAIRKNYLPIATRGALLYFLVADLTQINYMYQFSLDWFHQVFVSSVVSKS 3553
Query: 3756 KVED-------------------------------MQGRISILMESITHAVFLYTSQALF 3784
K ++ + I ++ +T ++F S ALF
Sbjct: 3554 KEQEHSFKREKVSPKEVHEFISISKEPNLENEKNLLDKHIKSAIDMLTKSIFKVVSSALF 3613
Query: 3785 EKDKLTFLSQMAFQILLRKKEIDPLELD--FL-------------------------LRF 3817
+DKL F ++ I+ + ++ D FL L
Sbjct: 3614 NEDKLCFSFRLCTVIMQNNANGNLIQDDIGFLPEEEWNIFLYSGILINIKSALSQSRLTS 3673
Query: 3818 TVEHTHLSPVDFLTSQSWSAIKAIAV-MEEFRGIDRDVEGSAKQWRKWVESEC------- 3869
T E + +L+ W + ++ +E F + + + + QW + S+
Sbjct: 3674 TFEIGESQHLQWLSDSRWRQCQYVSTHLEPFSLLCKSLLSNVSQWDTFKNSKAVYSLIST 3733
Query: 3870 ---------PEKEKLPQE-----------------WKKKSLIQKLILLRAMRPDRMTYAL 3903
E K P+E W+K + Q+LIL++ +RP+ + ++
Sbjct: 3734 PFSSENASLEENTKPPEETELLNENKETCNPINFPWEKLTSFQRLILVKVLRPESLNNSV 3793
Query: 3904 RNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDALKDLEILGKRLGFTIDS 3963
R F+ EK+G KY++RT ++L A++ S+ TP+ I + G+D L + L
Sbjct: 3794 RKFITEKMGNKYLQRTGVNLKDAYKGSNARTPLILIQTHGIDLTNILLRFAQEL-----K 3848
Query: 3964 GKFHNV---SLGQGQETVAEVALEKA-SKGGHWVILQNVHLVAKWLGTLEKLLERFSQGS 4019
G H+V SLG+ Q AE + KA +K WV LQN HL ++ L ++E F+ +
Sbjct: 3849 GTTHHVTIISLGRDQAAKAEDLILKALTKTQQWVFLQNCHLATSFMPRLCTIVESFNSPN 3908
Query: 4020 ---HRDYRVFMSAESAPTPDEHIIPQGLLENSIKITNEPPTGMLANLHAAL-----YNFD 4071
++R+++S++S + P +L+ +KI E P G+ +NL
Sbjct: 3909 VTIDPEFRLWLSSKSYSS-----FPIPVLKKGLKIAVESPQGLKSNLLQTFGCTGSGEVT 3963
Query: 4072 QDTLEICSKEQEFKSILFSLCYFHACVAGRLRFGPQGWSRSYPFNPGDLTICASVLYNYL 4131
++ E Q +K +LFSLC+F+A + R +G GW+ +Y FN DL + VL N L
Sbjct: 3964 EEIFENPDCGQWWKKLLFSLCFFNAVINERKNYGILGWNIAYKFNSSDLGVAIKVLENSL 4023
Query: 4132 EANSKVPWEDLRYLFGEIMYGGHITDDWDRKLCRVYLEEFMNPSLTEDELMLAPGFAAPP 4191
+ W+ LRYL GE++YGG + D+WD++ + L +F NP + +D+ + +
Sbjct: 4024 RGQPSISWQALRYLIGEVIYGGRVIDNWDKRCLKTLLYKFCNPEVLKDDFSFSRSASIKD 4083
Query: 4192 YLDYAGYHQYIEEMLPPES-PALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALSGDEL 4250
Y+ +I + LP + P + G+HP A L+ MQP+ + +
Sbjct: 4084 YI-------HIIQSLPDDDLPEVLGIHPEAIRSCWETQGEKFIENLIAMQPKTTTANLMI 4136
Query: 4251 --GQSTEEKVKNVLDDILEKLPEEFNMAEI-------------------MQKNSNRSPYV 4289
QS +E V +L D+L++LP EI + KN +
Sbjct: 4137 RPEQSKDELVMEILSDLLKRLPLTVEKEEIAVGTPSTLKSMMSSSIWESLSKNLKDHDPL 4196
Query: 4290 LVCF------QECERMNILIREIRISLEQLDLSLKGELALSPAVEAQQFALSYDTVPDTW 4343
+ C QE +R + L+ I SL+ L L++KGE+ L+ +E + VP W
Sbjct: 4197 IHCVLLTFLKQEIKRFDKLLFVIHKSLKDLQLAIKGEIILTQELEEIFNSFLNMRVPTLW 4256
Query: 4344 SKLAYPSTYGLAQWFNDLLLRCRELDTWTQDL---------------------------- 4375
K AY S L+ W +DL+ R +TW +
Sbjct: 4257 QKHAYRSCKPLSSWIDDLIQRLNFFNTWAKVAYTAIQRRYMRFVTVWKQSIPSTSQKCKH 4316
Query: 4376 ----------TLPAVVWLSGFFNPQSFLTAIMQTMARKNEWPLDKTRLT----ADVTKKT 4421
P+ WL FF PQ+FL A++Q R +D T ++ T K
Sbjct: 4317 PEDSENNFFEGFPSRYWLPAFFFPQAFLAAVLQDYGRSRGIAVDALTFTHHVISNTTDKD 4376
Query: 4422 KEDYGHPPRE----------------GAYLHGLFMEGARWDTQAGTIVEARLKELACPMP 4465
++ P++ G Y+ GLF+EGARW+ + + ++ E+ C P
Sbjct: 4377 EKFSVFMPKKLNIVRRAFKGSASSHTGVYIFGLFIEGARWNREQKILEDSLPLEMCCDFP 4436
Query: 4466 VIFAKATPVDRQ---ETKQT------YECPVYRTKLRG---------PSYIWTFRLKSEE 4507
I+ T + + + QT +ECPVY+T R +++ + L +++
Sbjct: 4437 DIYFLPTKISTKTPNASNQTDSELYAFECPVYQTPERSRILATTGLPTNFLTSVYLSTKK 4496
Query: 4508 KTAKWVLAGVALLLE 4522
+ W+ VALL E
Sbjct: 4497 PPSHWITMRVALLCE 4511
Score = 625 bits (1613), Expect = e-178
Identities = 441/1410 (31%), Positives = 681/1410 (48%), Gaps = 208/1410 (14%)
Query: 1302 STRLFEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTKTQWRQIHVEQMDVEL- 1360
S + E+ ++ ++ L K LW+ +R+ +W +WR ++ +DVE
Sbjct: 975 SVNVEEITQIVLSEISDIEGDLTLRKKLWEAQEEWKRA--SW---EWRNSSLQSIDVESV 1029
Query: 1361 -RRFAKASSITEIWSLNKEVRVWDAYTGLEGTVKDMTASLRAITELQSPALRDRHWHQLM 1419
R +K I + L K + D T L+ V + L I L +P L+ RHW L
Sbjct: 1030 QRNVSKLMHIISV--LEKGLPKSDMVTHLKQVVTEFKQELPIIIALGNPCLKPRHWEALQ 1087
Query: 1420 KAIGVKFLINEATTLADLLALRLHRVEDDVRRIVDKAVKELGTEKVITEISQTWATMKFS 1479
+ IG +++ + +LLAL++ + E+++ + A E EK++ +I W T
Sbjct: 1088 EIIGKSVPLDKNCKVENLLALKMFQYENEINDMSTSATNEAALEKMLFKIIDFWNTTPLP 1147
Query: 1480 YEVHYRT--GIPLLKSDEQLFETLEHNQVQLQTLLQSKYVEYFIEQVLSWQNKLNIADLV 1537
+H+ I ++ S + + LE +QV L T+ S ++ + V W L +
Sbjct: 1148 LILHHTEIYSIFIIPSIDDISAQLEESQVILATIKGSPHIGPIKDLVNEWDQNLTLFSYT 1207
Query: 1538 IFTWMEVQRTWSHLESIFVCSEDIRIQLVKDARRFDGVDAEFKELMFKTAKVENVLEATC 1597
+ WM QR W +LE +F SE IR QL + F V + +K++M K +N L+ T
Sbjct: 1208 LEEWMNCQRNWLYLEPVFHSSE-IRRQLPAETELFSQVISMWKKIMSKIQNKQNALQITT 1266
Query: 1598 RPNLYEKLKDLQSRLSLCEKALAEYLETKRIAFPRFYFVSSADLLDILSKGAQPKQVTCH 1657
+ E L++ L +K+L +YLE KR+ FPRFYF+S+A+LLDIL+ P+ V H
Sbjct: 1267 SAGVLEILQNCNIHLEHIKKSLEDYLEVKRLIFPRFYFLSNAELLDILADSRNPESVQPH 1326
Query: 1658 LAKLFDSIADLQFEDNQDVSAHRAVGMYSKEKEYVPFQAECECVGHVETWLLQLEQTMQE 1717
L K F++I L QD+ + S E E + + VE WL+ +E++M +
Sbjct: 1327 LVKCFENIKQLLIW-KQDIGPPAVKMLISAEGEGLVLPKKIRVRSAVEQWLVNVEKSMFD 1385
Query: 1718 TVRHSITEAIVAYEEKPRELWIFDFPAQVALTSSQIWWTTDVGIAFSRLEEGYETALKDF 1777
++ +E +I++ + L SQI + D +F + L+
Sbjct: 1386 VLK--------------KERYIYNI---ILLFQSQIMFYNDCVKSF--VSSYSREKLEKV 1426
Query: 1778 HKKQISQLNTLITLLLGELPPGDRQKIM-TICTIDVHARDVVAKLISQKQVVVSPQAFTW 1836
H + L + L++ + + I+ + + VH RD+V L+ + + + + F W
Sbjct: 1427 HAGLMCHLEEVADLVVLDTSNSRTKAILGALLILYVHCRDIVINLLLKN--IFNAEDFEW 1484
Query: 1837 LSQLRHRWEDTQKHCFVNICDAQFQYFYEYLGNSPRLVITPLTDRCYITLTQSLHLTMSG 1896
L+++W + QK C+V+ +A F Y YEYLG + RLVITPLTDRC++TL ++LHL + G
Sbjct: 1485 TRHLQYKWNEKQKLCYVSQGNASFTYGYEYLGCTSRLVITPLTDRCWLTLMEALHLNLGG 1544
Query: 1897 APAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGAWGCFDEFNR 1956
PAGPAGTGKTET KDL ++LG VFNC E +DYK + + GLVQ+GAW CFDEFN
Sbjct: 1545 CPAGPAGTGKTETVKDLAKSLGKHCVVFNCFEDLDYKIVRKFFFGLVQSGAWSCFDEFNL 1604
Query: 1957 ISVEVLSVVAVQVKMIHDAIRNRKKRFVFLGEAITLKPSVGIFITMNPGYAGRTELPENL 2016
I +EVLSV+A Q+ I A N RFV G+ I + S +FITMNP Y G ELP+NL
Sbjct: 1605 IDLEVLSVIASQILTIKAAKDNYSARFVLEGKEIRINMSCAVFITMNPRYGGGVELPDNL 1664
Query: 2017 KALFRPCAMVAPDIELICEILLVAEGFVDARALARKFITLYTLCKELLSKQDHYDWGLRA 2076
K+LFRP AM+ P ++I EI+L + GF A +L+ K LY L ++ LS+QDHY++GLR+
Sbjct: 1665 KSLFRPVAMMVPHYQMIAEIILFSFGFKSANSLSGKLTNLYELARKQLSQQDHYNFGLRS 1724
Query: 2077 IKSVLVVAGSLKRGDK---NRPEDQVLMRALRDFNMPKIVTDDIPVFLGLVGDLFPALDV 2133
+K VL++AG+ KR K E +++ A+R+ ++PK +D+P+F ++GD+FP + V
Sbjct: 1725 LKIVLIMAGTKKREFKCLSEADETLIVIEAIREASLPKCPPEDVPLFENIIGDIFPEVTV 1784
Query: 2134 PRRRKLHFEQMVRQSTLELRLQPEESFILKVVQLEELLAVRHSVFVVGNAGTGKSKILRT 2193
+ +L E+++ +T +L LQ S K++Q L V V +VG G GK+ + R
Sbjct: 1785 LKVNQLALEKVIYTATQQLGLQNWSSQKEKIIQFYNQLQVCVGVMLVGPTGGGKTTVRRI 1844
Query: 2194 LNRTYV--------------------NMKQKPVWNDLNPKAVTTDELFGFIHHATREWKD 2233
L + K K LNPK VT EL+G + T EW D
Sbjct: 1845 LEKALTLLPIADFLSVAERKSASKISERKGKVDICVLNPKCVTLSELYGQLDPNTMEWTD 1904
Query: 2234 GKI-----VYSYF-----------IGLFSSILREQANLKHDGP----------------- 2260
G + Y YF + L S I K D
Sbjct: 1905 GLLSATIRSYVYFNTPKNTKKDIDLRLKSRISDLSNVFKLDSSDTTETDDNIFEEIEKVV 1964
Query: 2261 ----------KWIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIALTPFMRLLFEIHHL 2310
+WI+LDG +D W+E+LN+V+DD + L LA++ERIALT +R++FE+ +L
Sbjct: 1965 KIPENHNFDWQWIILDGPVDTFWVENLNSVLDDTRTLCLANSERIALTNKIRVIFEVDNL 2024
Query: 2311 RSATPATVSRAGILYVNPQDLGWNPYVASWI----------------------------- 2341
A+PATVSR ++Y++P DLGW PYV SW+
Sbjct: 2025 SQASPATVSRCAMVYMDPVDLGWEPYVKSWLLKTSKIISQSGVDCLEFMIKNSVTDGLQF 2084
Query: 2342 --DRRRHQ---SEKANLTILFDKYVPACLDKL-------------RTSFKTITSIPESSL 2383
+R++ Q E + I + + A D + TS K S ES
Sbjct: 2085 IRNRQKFQPYPMEDITVVITLCRILDAFFDFMGKNGGFEQSDDLNDTSSKEANSQRESVT 2144
Query: 2384 VQTLCVLLECLLTPENVPSDSPKEVYEVYFVFACIWAFGGTLLQ---------------- 2427
+ + E PE P D ++ + FVFA WAFGG L +
Sbjct: 2145 FKDIEKRDENTWYPEKNP-DKLTKIIQKLFVFAFTWAFGGALNREDEHRENIPFCPSLEP 2203
Query: 2428 DQISDYQADFSR----------------WWQKEMK-----AVKFPS-QGTIFDYYVDHKT 2465
D ++ DF + W Q + + + P+ + +IF Y+VD +
Sbjct: 2204 DSLAKVTYDFDKLVHELFGNSSQVGWKHWGQSQGRRRKGNCINLPTGECSIFGYFVDIEQ 2263
Query: 2466 KKLLPWADKIA--QFTMDPDVPLQTVL-------------------VHTTETARLRYFME 2504
+ +PW+D + Q + L T L T +T L + M
Sbjct: 2264 CEFIPWSDLVPNDQTLIQRGTSLLTNLQRSGGNFLKITECGECINYTATRDTTCLSFLMS 2323
Query: 2505 LLLEKGKPLMLVGNAGVGKTVFVGDTLASL 2534
LLL+ P++L G +GVGKT + L L
Sbjct: 2324 LLLKNSCPVLLTGESGVGKTAAINQMLEKL 2353
Score = 144 bits (364), Expect = 2e-33
Identities = 89/263 (33%), Positives = 134/263 (50%), Gaps = 7/263 (2%)
Query: 2539 IVSRVPFNYYTTSTALQKILEKPLEKKAGHNYGPGGNKKLIYFIDDMNMPEVDLYGTVQP 2598
+VS + F+ T+ ++++ K L ++ G N +++ FIDDMNMP D+YG P
Sbjct: 2426 VVSTINFSTNVTAAKTKEMILKKLIRRTKDTLGAPKNNRILIFIDDMNMPVSDMYGAQPP 2485
Query: 2599 HTLIRQHIDYGHWYDRQKVMLKEIHNCQYVACMNPMVGSFTINPRLQRHFTVFAFNFPSL 2658
LIRQ +D G YD +K K I + VA P+V I+PRL +HF++ PS
Sbjct: 2486 LELIRQLLDLGGVYDTEKNTWKNIQDLSIVAACVPVVND--ISPRLLKHFSMLVLPHPSQ 2543
Query: 2659 DALNTIYGQIFSFHFQQQAFAPSILRSGPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLR 2718
D L TI+ +F F P + +S +I ++A + + N LPT K HY+FNLR
Sbjct: 2544 DILCTIFQAHLGIYFSINNFTPEVQKSKDQIISCSLAIYHQVRQNMLPTPTKCHYMFNLR 2603
Query: 2719 DLSNVFQGILFASPECLKGPLDLIHLWLHESARVYGDKLIDKKDCDLFQR---RMLETAY 2775
D+ + G+L A + L++HE+ RV+ D+LID D LF R R LE +
Sbjct: 2604 DMFKLLLGLLQADRTVVNSKEMAALLFVHEATRVFHDRLIDFTDKSLFYRLLSRELENCF 2663
Query: 2776 KYFEGIDSHMLLQQPLIYCHFAD 2798
+ GID + C+ D
Sbjct: 2664 QI--GIDGCGKKTCATLACYLTD 2684
>gi|222144249 dynein heavy chain domain 1 isoform 1 [Homo sapiens]
Length = 4753
Score = 187 bits (474), Expect = 3e-46
Identities = 333/1636 (20%), Positives = 622/1636 (38%), Gaps = 298/1636 (18%)
Query: 1399 LRAITELQSPALRDRHWHQLMKAIGVKFLIN-EATTLADLLALRLHRVEDDVRRIVDKAV 1457
L +T+L S + + L++A+G+ L E TL LL L D + ++
Sbjct: 1087 LPLLTKLGSLHPQSLNCQCLLRALGLGSLQTIELLTLGQLLTYPLLEFADRINQVWQNEN 1146
Query: 1458 KELGTEKVITEISQTWAT-----MKFSYEVHYR-----------------------TGIP 1489
+ + ++ I + + W + F V Y +G
Sbjct: 1147 ERIHAQETIRRLQRYWEARQLRLLNFILHVPYEPPASERSKRQVLRSPQWEVVDKDSGTF 1206
Query: 1490 LLKSDEQLFETLEHNQVQLQTLLQSKYVEYFIEQVLSWQNKLNIADLVIFTWMEVQRTWS 1549
+L L ++++ + L +L + + L W ++ ++ W+ Q+ W
Sbjct: 1207 ILSDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLGALLEVWLTFQQKWI 1266
Query: 1550 HLESIFVCSEDIRIQLVKDA--RRFDGVDAEFKELM---FKTAKVENVLEATCRPNLYEK 1604
L + +++IQ RF +D +++ LM V +++ + + Y +
Sbjct: 1267 FLNKVL---HEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVPSAERSPYFQ 1323
Query: 1605 LKDLQSRLSLCEKALAEYLETKRIA-------FPRFYFVSSADLLDILSKGAQPKQVTCH 1657
+ LQ L L + + FPR +F+S ++L+ +L+ + +
Sbjct: 1324 GQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAARLESCEAQLW 1383
Query: 1658 LAKLFDSIADLQF------EDNQD--------VSAHRAVGMYSKEKEYVPFQAECECVGH 1703
+ + F + + F E N D + A+ + E V Q
Sbjct: 1384 VRRCFPHVHAVSFRSCPTGEKNTDDWESSPNTQTQVEALAVLGAGGEEVKLQGPLPLHPD 1443
Query: 1704 VETWLLQLEQTMQETVRHSITEAIVA-----------YEEKPRELWIF------------ 1740
+ WL LE+ ++ + H + + A ++ P++ ++
Sbjct: 1444 LPKWLASLEKCLRLALVHMLQGCVAARLARGPSLGEALKQLPKQNKLYLQLYVQHWIDLV 1503
Query: 1741 -DFPAQVALTSSQIWWTTDVGIAFSRLEEGYETALKDFHKKQISQLNTLITLLL----GE 1795
FP Q L + ++ W ++ A LE G A+ H +++ L + G+
Sbjct: 1504 QAFPWQCVLVAEEVVWRAEMEEAL--LEWG-TLAMVSMHMRKLEVLVNFMRAQRASQGGQ 1560
Query: 1796 LPPGDRQK--IMTICTIDVHARDVVAKLISQKQVVVSPQAFTWLSQLRHRWED------- 1846
P RQ + + + V RD+ A+L+ Q QV F W+ QL++
Sbjct: 1561 SLPSVRQTSLLSALLVMAVTHRDI-AQLLEQHQVSDLTD-FHWVRQLKYHLGSPHIIPKS 1618
Query: 1847 ---------------TQKHCFVNICDAQFQYFYEYLGNSPRLVITP--LTDRCYITLTQS 1889
+ C++++ F Y YEYLG PRL P L +R + L +
Sbjct: 1619 PLQSLKTIASSEPSLSPAACWIDVLGRSFLYNYEYLG--PRLGPLPSLLPERPALVLLLA 1676
Query: 1890 LHLTMSGAPAGPAGTGKTETTKDLGRALGMMVYVFNCSEQMDYKSIGNIYKGLVQTGAWG 1949
L G GP G GK L +ALG + + CS Q++ + + N G +Q GAW
Sbjct: 1677 LEEVACGTVLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWL 1736
Query: 1950 CFDEFNRISVEVLSVVAVQVKMIH--------DAIRNRK----KRFVFLGEAITLKPSVG 1997
++ +++ +LS + ++ +H +A RN + LG + K V
Sbjct: 1737 LLEKVHQLPPGLLSALGQRLGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHVS 1796
Query: 1998 IFITMNPGY-------AGRTELPENLKALFRPCAMVAPDIELICEILLVAEGFVDARALA 2050
+ + GY A + +P NL L RP A+ PD+ + E+ L+ G DA +A
Sbjct: 1797 VRL----GYGCLLVLRALSSAVPANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMA 1852
Query: 2051 RKFITLYTLCKELLSKQDHYDWGLRAIKSVLVVAGSLKRGDKNRPEDQVLMRALRDFNMP 2110
+ ++L +EL+S L +K +L K P+ Q R+L
Sbjct: 1853 TRLSKFFSLERELVS--GPLPCRLPLLKQILEDTIRTLNVTKEEPKCQ-KPRSLAAIEEA 1909
Query: 2111 KIVTDDIPVFL---------GLVGDLFPA----LDVPRRRKLHFEQMVRQSTLELRLQPE 2157
++ + L GL+ LFP+ L P KL + +V + ++ L P
Sbjct: 1910 ALLRSPLFSILNGLHLHNLRGLLCALFPSASQVLAEPMTYKL-MKPLVVEELQQVGLDPS 1968
Query: 2158 ESFILKVVQLEELLAVRHSVFVVGNAGTGKSKI----------LRTLNRTYVNMKQKPVW 2207
+ + QL + L+ + ++G AG+GK+ L + T Q
Sbjct: 1969 PDILGSLEQLSQALSRASGILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEI 2028
Query: 2208 NDLNPKAVTTDELFGFIHHATREWKDGKIVYSYFIGLFSSILREQANLKHDGPK------ 2261
L P ++ E G W +G + G+F +LR + G K
Sbjct: 2029 THLYPSGLSPQEFLG--------WLEGS---CWHHGIFPKVLRAAGQCNNMGQKRQTEES 2077
Query: 2262 -----WIVLDGDIDPMWIESLNTVMDDNKVLTLASNERIALTPFMRLLFEIHHLRSATPA 2316
WI+ DG + W++S+ ++ + L+L S ++IA P LL E+ +P
Sbjct: 2078 IGIQHWIICDGASNGAWLDSITCLLSELPQLSLPSGQQIARPPGTFLLMEVADTTGISPT 2137
Query: 2317 TVSRAGILYVNPQDLGWNPYVASWI-----DRRRHQSEKANLTILFDKYVPACLDKLRTS 2371
V +++ + W +++ + + R A L + + VPA L L +
Sbjct: 2138 VVGCCALVWCGGEQT-WQCILSALMASLPYEYRLQHRTVAELNHMAEVLVPATLRFL--T 2194
Query: 2372 FKTITSIPESSLVQTLCV----------LLECLLT------------PENV--------- 2400
+ ++S+ + Q +C +L LL PE++
Sbjct: 2195 CQGVSSLLQVHGQQAVCAGVAEVTSMARILHSLLDLHLRLKEEKAPGPEDLSYSDPVAQS 2254
Query: 2401 ---------------PSDSPKEVYE-----VYFVFACIWAFGGTLLQDQISDYQADFSRW 2440
D P + E F+FA IW FG L +
Sbjct: 2255 FRSSKSSFLNRSQVDSDDVPDKCREHLLAVSSFLFALIWGFGAHLPSRFWPIFDTFIRDS 2314
Query: 2441 WQKEMKAVKFPSQGTIFDYYVDHKTKKLLPWADKIAQFTMDPDVPLQTVLVHTTETARLR 2500
+ + P +FD +V + L+P+ Q+ + +T RL
Sbjct: 2315 ISRLSNYPEPPPSALVFDLHVSPEDGTLVPFT---GQYLSSHIKGTLGTFHPSIQTERLL 2371
Query: 2501 YFMELLLEKGKPLMLVGNAGVGKTVFVGDTLASLSEDYIVSRVPFNYYTTSTALQKILEK 2560
Y ++LLL G+P++L G A GK+ FV + L YI S P + +S+ L+ +L +
Sbjct: 2372 YVVDLLLSGGQPVLLAGEAATGKSAFV-EVLVEPHHPYIYS--PIHPAFSSSHLRLLLSR 2428
Query: 2561 PLEKKAGHNYGPGGNK----KLIYFIDDMNMPEVDLYGTVQP-HTLIRQHIDYGHWYDRQ 2615
++ + + PG ++ L++ ++D+++ D + QP +RQ +D G Y
Sbjct: 2429 GIQGQTQASPQPGHHQDSKPSLLFLLEDLHLATSDPEKSCQPVLETLRQAMD-GTVYAHS 2487
Query: 2616 KVMLKEIH-NCQYVACMN-PMVGSFTINPRLQRHFTVFAFNFPSLDALNTIYGQIFSFHF 2673
+ L+ + ++A + P + PRL R FTV A + L + I
Sbjct: 2488 TLELQTLQPTVNFLATVTVPGYCERPLCPRLFRLFTVLALESMTQATLLERHVPIIQAWL 2547
Query: 2674 QQQAFAPSILRS---GPTLIQATIAFHQTMMCNFLPTAIKFHYIFNLRDLSNVFQGI-LF 2729
++ PS+ R L++A++ + + F+P+ + HY F+L +S++ + L
Sbjct: 2548 ER---FPSVERERALARGLVRASVEAWEAVCNCFMPSPLHPHYHFSLHSVSHLLSSLQLL 2604
Query: 2730 ASPECLKGPLD---------------------------LIHLWLHESARVYGDKLIDKKD 2762
+ +G +D ++ LWLHE+ R + D+L ++
Sbjct: 2605 PNRTGSRGFVDYPNHQEHLRRVSGLRGTCLTVMMATRNVVRLWLHEAQRTFCDRLDSPRE 2664
Query: 2763 CDLFQRRMLETAYKYF 2778
+ +L A F
Sbjct: 2665 RSYCAKLLLVVAQSVF 2680
Score = 132 bits (332), Expect = 8e-30
Identities = 180/812 (22%), Positives = 325/812 (40%), Gaps = 97/812 (11%)
Query: 2760 KKDCDLFQRRMLETAYKYFEGIDSHMLLQQPLIYCHFADRGKDPHYMPVKDWEVLKTILT 2819
K DL +L + + S ++ Q LI + P+ + WE L+ L
Sbjct: 2794 KPQMDLISPLLLPVLLLHPQEKPSDLVFSQELI---LGPNSETPNLYLERQWEKLEEQLA 2850
Query: 2820 ETLDNYNELNAAMHLVLFEDAMQHVCRISRILRTPQGCALLV-GVGGSGKQSLSRLAAYL 2878
+ +L + HL QHV R+ R+L P+ LL+ G G+G+ + LA+ +
Sbjct: 2851 TSAA---QLKLSPHLARCHSMAQHVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSI 2907
Query: 2879 RGLEVFQITLTEGYGIQELRVDLANLYIRTGAKNMPTVFLLTDAQVLDESFLVLINDLLA 2938
F + I + D + G + P L+ +D + L + L
Sbjct: 2908 CQAHFFHLPSGSEEAILQCLRDAS---WHAGMLSQPVALLVPSG--VDLTTLHRLLALAT 2962
Query: 2939 SGEIPDLFSDEDVDKIISGIHNEVHALGMVDSRENCWKFFMARVRLQLKIILCFSPVGRT 2998
SG P +++ D+D+I + E + +E + F +V L +
Sbjct: 2963 SGSFPGQYTEADLDRIGEHLPRENLGVKQNIKKEMVLQRFHQQVCSHLHLFFLIGDKQAH 3022
Query: 2999 LRVRARKFPAIVNCT--AIDWFHAWPQEALVSVSRRFIEETKGIEPVHKDSISL--FMAH 3054
++ + F ++ +ID + W Q AL V++ +E + + P+ S A
Sbjct: 3023 KQLPSTLFLRLLQLATASIDRYEPWDQAALAKVAQHHLEGAQSV-PLDDGSWKYPDLQAS 3081
Query: 3055 VHTTVNEMSTRYYQNERRHNY-------TTPKSFLEQISLFKNLLKKKQNEVSEKKERLV 3107
+ + M+ + H + TPK+FL+ + F L ++ ++ K +R+
Sbjct: 3082 IPSVAKAMALIHLSATHYHEHLCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQ 3141
Query: 3108 NGIQKLK-------TTASQVGDLKARLASQEAELQLRNHDAEALITKIGLQTEKVSREKT 3160
N ++ L+ T A+ + DL+ +L L + E Q E+ ++
Sbjct: 3142 NALENLRMLIKEHGTHANLIFDLEQQLKDSGKSLSMFQQQLEQSKLLYKQQLEECRHQEN 3201
Query: 3161 IADAEERKVTAIQTEVFQKQRECEADLLKAEPALVAATAALNTLNRVNLSELKAFPNPPI 3220
+ + R Q + Q QRE + + A L+ L + E++++ PP
Sbjct: 3202 LIENLAR-----QRDALQAQREAFLEQMSK-----AFLEPLSQLQVADFEEIRSYRAPPE 3251
Query: 3221 AVTNVTAAVMVLLAPRGRVPKDRSWKAAKVFMGKVDDFLQALINYDKEHIPENCLKVVNE 3280
+V VT A+ L + W +AK + +DF Q L+ + KE I ++ +++
Sbjct: 3252 SVVRVTDAMCDLFH------HETGWASAKQLLC-TEDFYQELVFFPKEKITDS--ELIKL 3302
Query: 3281 HY-LKDPEFNPNLIRTKSFAAAGLCAWVINIIKFYEVYCDVEPKRQALAQANLELAAATE 3339
H LK P + +R S AA L AW+ ++ + +C P L Q L
Sbjct: 3303 HLILKAPGMDDAALRAVSRPAASLAAWLWAVLHYGLAHCRGLPTDLLLQQVEATLTREQA 3362
Query: 3340 KLEAIRKKLVD-LDRNLSRLTASFEKATAE-----KVRCQEEVNQTNKTIKLANRLVKEL 3393
+L + + + L+ NL+ L E A A K Q + Q +K A L+ +
Sbjct: 3363 RLGYYQFQAQETLEHNLA-LAKMVEDAQASHNCVAKTLSQAQCGQYHKWPMKA-ALLTPM 3420
Query: 3394 EAKKIRWGQSIKSFEAQEKTLCGDVLLTAAFVSYVGPFTRQYRQELVHCKWVPFL----- 3448
A W ++ + + T+ GD LL +A + Y+GPF RQEL+ +W+
Sbjct: 3421 RA----WTTQLQKLKGRCMTVFGDTLLCSAAIIYLGPFPPLRRQELLD-EWLALCRGFQE 3475
Query: 3449 --------------QQKVSIPLTEGL-------DLISMLTDDATIAAWNNEGLPSDRMST 3487
Q+ VSIP L ++S+L+ ++ W+ P + S
Sbjct: 3476 ALGPDDVAQALKRKQKSVSIPPKNPLLATHSPFSILSLLSSESEQYQWDGNLKPQAK-SA 3534
Query: 3488 ENAAIL----THCE--RWPLVIDPQQQGIKWI 3513
A +L TH RWPL++DP + + W+
Sbjct: 3535 HLAGLLLRSPTHYSSCRWPLLLDPSNEALIWL 3566
Score = 89.7 bits (221), Expect = 6e-17
Identities = 197/984 (20%), Positives = 355/984 (36%), Gaps = 110/984 (11%)
Query: 3602 ELQAQTTLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLEDDLL 3661
EL +L+ + + LE Q+L E++ E P+LE L D ++ E+ LL
Sbjct: 3740 ELLKGLNVLDLGLNMEILEEQMLHEILCREYPELETRWQDLKIRALDTCKAVEAAEERLL 3799
Query: 3662 LRLSAAEGSFLDDTKLVERLEATKTTVAEIEHKVIEAKENERKINEARECYRPVAARASL 3721
L K + + + + ++ E + + + YRPV
Sbjct: 3800 TMLLFQNPKRQKPAKFLRNIVRAQGKLCQLRAHCEELEGQKLQEMVLWAPYRPVVWHGMA 3859
Query: 3722 LYFVINDLQKINPLYQFSLKAFNVLFHRAIE-----QADKVEDMQGRISILMESITHAVF 3776
+ ++ LQ + PL+ S + + + +A++ + + ED+ + L +T +
Sbjct: 3860 MVKALSQLQNLLPLFCMSPENWLAVTKQALDSMKPREINHGEDLASHLLQLRAHLTRQLL 3919
Query: 3777 --LYTSQALFEKDKLTFLSQMAF-QILLRKKEIDPLELDFLLRFTVEHTHLSPVDFLTSQ 3833
T+ L + + L +A Q + E++ L L L + H PV +
Sbjct: 3920 GSTVTALGLTQVPLVGALGALALLQATGKASELERLALWPGLAASPSTVHSKPVSDVARP 3979
Query: 3834 SWSAIKA------IAVMEEFRGIDRDVEGSAKQWRKWVESECPEKEKLPQEWKKK-SLIQ 3886
+W KA + ++ F G+ + G + W+ ++ P + SL+Q
Sbjct: 3980 AWLGPKAWHECEMLELLPPFVGLCASLAGHSSAWQAYLSLSSTVLGPAPGPGPEPLSLLQ 4039
Query: 3887 KLILLRAMRPDRMTYALRNFVEEKLGAKYVERTRLDLVKAFEESSPATPIFFILSPGVDA 3946
KLIL R +RP+ + AL +F LG E T + F+ S P+ +L P
Sbjct: 4040 KLILWRVLRPECLAGALADFTTSLLGRPLDENTYAPTM-PFKHSQATQPMLILLPPPGHP 4098
Query: 3947 LKDLEILG--KRLGFTIDSGKFHNVSLGQGQE-----TVAEVALEKASKGGHWVILQNVH 3999
L L ++L G+ + G E +V L +A GHW++L N H
Sbjct: 4099 SATLHPLTVIQKLAAKYQQGQKQLQVIALGSEAWDPVSVVVSTLSQAMYEGHWLVLDNCH 4158
Query: 4000 LVAKWLGTLEKLL-----------------------ERFSQGSHRDYRVFMSAESAPTPD 4036
L+ W L +LL R HRD+R+++ P
Sbjct: 4159 LMPHWPKELLQLLLELLGRAKVVADLESEQLLDQPESRNVSTVHRDFRLWL---IVPAES 4215
Query: 4037 EHIIPQGLLENSIKITNEPPTGMLANLHAALYNFDQDTLEICSK--EQEFKSILFSLCYF 4094
+P L ++S+ + N L + D++E+ + + + L
Sbjct: 4216 SASLPAVLTQHSMPV--------FWNQSLELGHVLIDSVELAQQVLYMQPPTQALPLLLL 4267
Query: 4095 HACVAGRLRFGPQGWSRSYPFNPGDLTICASVLYNYLEANSKVPWEDLRYLFGEIMYGGH 4154
H + R +G + + ++ LT + L A+ P ++ L + YGG
Sbjct: 4268 HGLLLHRQLYGTRLQAHRGRWSQVTLTQVLQT-QDQLWASLSNPRAAMQELAASVFYGGP 4326
Query: 4155 ITDDWDRKLCRVYLEEFMNPSLTE------DELMLAPGFAAPPY--LDYAGYHQYIEEML 4206
+ D DR+ + ++PS + +LA P LD + +L
Sbjct: 4327 LGDTEDREALISLTQACLSPSSGSWVQPHTPQSLLATLMPLPELRELDAMAECKAQMHLL 4386
Query: 4207 P-PESPALYGLHPNAEIEFLTVTSNTLFRTLLEMQPRNALSGDELGQSTEEKVKNVLDDI 4265
P P P L GL + L S L L P Q E +++ L +
Sbjct: 4387 PSPPEPRLCGLSEGPQAWLLRRQSRALLSALQRSSPVWVPESRRGAQLAERRLRQRLVQV 4446
Query: 4266 LEKLPE-EFNMAEIMQKNSNRSPYVL-----------VCFQECERMNILIREIRISLEQL 4313
+L + + +++++ + +P+ + V E ++ L+ ++ L+ L
Sbjct: 4447 NRRLESLQDLLTHVIRQDESDAPWSVLGPNARRPLEGVLETEALELSQLVGTLQRDLDCL 4506
Query: 4314 DLSLKGELAL-SPAVEAQQFALSYDTVPDTWSKLAYPSTYGLAQWF------NDLLLRCR 4366
LKG S A AL +P W A W LL+R
Sbjct: 4507 LQQLKGAPPCPSRRCAAVAHALWTGRLPLPWRPHAPAGPQPPWHWLRQLSRRGQLLVRYL 4566
Query: 4367 ELDTWTQDLTLPAVVWLSGFFNPQSFLTAI-----MQTMARKNEWPLDKTRLTADVTKKT 4421
+ V LS F +P+ L A+ + + +P + +++ + K
Sbjct: 4567 GVGADASSDVPERVFHLSAFRHPRRLLLALRGEAALDQNVPSSNFPGSRGSVSSQLQYKR 4626
Query: 4422 KEDYGHP-------------PREGAYLHGLFMEGARWDTQAGTIVEARLKELACPMPVIF 4468
E +P P G L GL + A WD AG + ++ + + PV
Sbjct: 4627 LEMNSNPLHFRVENGPNPTVPERGLLLIGLQVLHAEWDPIAGALQDSPSSQPSPLPPVSI 4686
Query: 4469 AKATP----VDRQETKQTYECPVY 4488
+ P + Y CPVY
Sbjct: 4687 STQAPGTSDLPAPADLTVYSCPVY 4710
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 47.4 bits (111), Expect = 3e-04
Identities = 87/459 (18%), Positives = 186/459 (40%), Gaps = 64/459 (13%)
Query: 1157 LQRELNEGDHD--GLVDIMVHLLAVRSRQ-RATDELFEPLKETITLLESYGQK------M 1207
LQ++L + + + GLV+ + L A+R+ +L L++ T +Y +K
Sbjct: 894 LQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDA 953
Query: 1208 PEQVYIQLEELPERWETTKK-IAATVRHEVSPLHNAEVTLIRKKCILFDAKQAEFRERFR 1266
E+ +L++ ET K+ I ++ + L L ++ LFD Q E R+R
Sbjct: 954 VEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQ---LFDDVQKEERQRML 1010
Query: 1267 HYAPLGFNAENPYTALDKANEELEALEEEMLQMQESTR---------LFEVA--LPEYKQ 1315
++ + EE++AL++E +Q+Q EVA + K
Sbjct: 1011 LEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKT 1070
Query: 1316 MKQCRKEIKLLKGLWDVIIYVRRSIDNWTKTQWRQIHVEQMDV--------ELRRFAKAS 1367
+ + KEI+LL+ + ++ ++Q R++ + ++ ++
Sbjct: 1071 ISEFEKEIELLQA-------QKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRL 1123
Query: 1368 SITEIWSLNKEVRVWDAYTGLEGTVKDMTA---SLRAITELQSPALRDRHWHQLMKAIGV 1424
S+ ++ LN++ +W AY GL+ + + + S + E + AL + H + +
Sbjct: 1124 SVEDLEHLNEDGELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHL 1183
Query: 1425 KFLINEATTLADLLALRLHRVEDDVRRIVD--KAVKELGTEKVITEISQTWATMKFSYEV 1482
+ L E + + + + R+ + I D + + EL +K EI K ++
Sbjct: 1184 QKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKL 1243
Query: 1483 HYRTGIPLLKSDEQLFETLEHNQVQLQTLLQSKYVEYFIEQVLSWQNKLNIADLVIFTWM 1542
+ L +S E+ E + ++ Q + +K E I+++
Sbjct: 1244 EELSN-QLHRSQEE--EGTQRKALEAQNEIHTKEKEKLIDKI-----------------Q 1283
Query: 1543 EVQRTWSHLESIFVCSEDIRIQLVKDARRFDGVDAEFKE 1581
E+Q HL+ F +++ ++A R + + +E
Sbjct: 1284 EMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEE 1322
>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
Length = 1233
Score = 45.4 bits (106), Expect = 0.001
Identities = 23/100 (23%), Positives = 61/100 (61%), Gaps = 7/100 (7%)
Query: 3083 EQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLASQEAELQLRNHDAE 3142
+++ +++ +KK +NE+ + K+ ++ + T +Q+ DLK + ++++E+ +NH+ E
Sbjct: 833 DKVHMWEQTVKKDENEIEKLKKEEQRHMKIIDETMAQLQDLKNQHLAKKSEVNDKNHEME 892
Query: 3143 ALITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQRE 3182
+ K+G ++++ +++VTAI+T++ QK+ +
Sbjct: 893 EIRKKLGGANKEMTH-------LQKEVTAIETKLEQKRSD 925
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 43.5 bits (101), Expect = 0.005
Identities = 51/256 (19%), Positives = 102/256 (39%), Gaps = 24/256 (9%)
Query: 1136 LRFVIDSLNELQEFIKETDSGLQREL---------NEGDHDG--LVDIMVHLLAVRSRQR 1184
L+ V +E+Q +KE L+R E DH G L + L A
Sbjct: 230 LQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENE 289
Query: 1185 ATDELFEPLKETITLLESYGQKMPEQVYIQLEELPERWETTKKIAATVRHEVSPLHNAEV 1244
+ L + +E + E Q+ E++ Q E++ E+ E ++ +R + + E
Sbjct: 290 LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE 349
Query: 1245 TLIRKKCILFDAKQAEFRERFRHYAPLGFNAENPYTALDKANEELEALEEEMLQMQESTR 1304
+ R++ ++++ + E+ R + + E L++ E E + E+ + QE +
Sbjct: 350 KMRRQEEMMWEKE-----EKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEK 404
Query: 1305 LFEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTKTQWRQIHVEQMDVELRRFA 1364
+ E + ++ K R+E K+ + I K WRQ ++R
Sbjct: 405 IREQEKRQEQEAKMWRQEEKIREQ--------EEKIREQEKKMWRQEEKIHEQEKIREEE 456
Query: 1365 KASSITEIWSLNKEVR 1380
K E+W +++R
Sbjct: 457 KRQEQEEMWRQEEKIR 472
Score = 34.7 bits (78), Expect = 2.2
Identities = 30/162 (18%), Positives = 68/162 (41%), Gaps = 16/162 (9%)
Query: 3021 WPQEALVSVSRRFIEETKGIEPVHKDSISLFMAHVHTTVNEMSTRYYQNERRHNYTTPKS 3080
W QE + + EE K E M + E + Q E+ H +
Sbjct: 440 WRQEEKIHEQEKIREEEKRQEQEE-------MWRQEEKIREQEEIWRQKEKMHEQEKIRK 492
Query: 3081 FLEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLASQEAELQLRNHD 3140
E++ + + ++ ++ E++E++ +K++ ++ + + ++ QE +Q +
Sbjct: 493 QEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEE- 551
Query: 3141 AEALITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQRE 3182
K+G Q EK+ ++ + EE+ Q E ++Q+E
Sbjct: 552 ------KMGEQEEKMQEQEKMRRQEEK--IREQEEKIREQKE 585
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 43.5 bits (101), Expect = 0.005
Identities = 87/421 (20%), Positives = 162/421 (38%), Gaps = 71/421 (16%)
Query: 3024 EALVSVSRRFIEETKGIEPVHKDSISLFMAHVHTTVNEMSTRYYQNERRHNYTTPKSFLE 3083
E + + + T+ + V +D + T +E+S R Q E T E
Sbjct: 1407 EEIKRLKNTLTQTTENLRRVEED-----IQQQKATGSEVSQRKQQLEVELRQVTQMRTEE 1461
Query: 3084 QISLFKNLLKKKQNEVSEKK---ERLVNGIQKLKTTASQVGDLKARLASQEAELQLRNHD 3140
+ +K L + +K ERL I K + D ARL + +LQ N
Sbjct: 1462 SVR-YKQSLDDAAKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQKANSS 1520
Query: 3141 AEALITKIGLQT----------EKVSREKTIADAEERKVTAIQTEVFQKQRECEADLLKA 3190
A I K+ +Q E+VS+E+T+ D + +T Q + K+ + + ++
Sbjct: 1521 ATETINKLKVQEQELTRLRIDYERVSQERTVKDQD---ITRFQNSL--KELQLQKQKVEE 1575
Query: 3191 EPALVAATAALNTLNRVNLSE-----LKAFPNPPIAVTNVTAAVMVLLAPRGRV------ 3239
E + TA+ ++ R L E ++ I +TN+T + + R
Sbjct: 1576 ELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDLRQ 1635
Query: 3240 ----------PKDRSWKAAKVFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLKDPEFN 3289
K R+ + + +V+ + L+ ++E + + L+ NEH+ K E
Sbjct: 1636 QRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQ-EQESVKQAHLR--NEHFQKAIEDK 1692
Query: 3290 PNLIRTKSFAAAGLCAWVINIIKFYEVYCDVEPKRQALAQANLELAAATEKLEAIRKKLV 3349
+ L + N+ K E E+L +R +
Sbjct: 1693 SRSLNESKIEIERLQSLTENLTK--------------------EHLMLEEELRNLRLEYD 1732
Query: 3350 DLDRNLSRLTASFEKATAEKVRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSIKSFEA 3409
DL R S S + AT ++R Q +++ N+T++L L+ +L+ ++ Q I+ F+
Sbjct: 1733 DLRRGRSE-ADSDKNATILELRSQLQIS-NNRTLELQG-LINDLQRERENLRQEIEKFQK 1789
Query: 3410 Q 3410
Q
Sbjct: 1790 Q 1790
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 42.0 bits (97), Expect = 0.014
Identities = 23/124 (18%), Positives = 56/124 (45%)
Query: 3070 ERRHNYTTPKSFLEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLAS 3129
E++ K ++++ + LK ++E+ + E L + +KL+ + D +A +AS
Sbjct: 29 EQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVAS 88
Query: 3130 QEAELQLRNHDAEALITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQRECEADLLK 3189
+QL + + ++ +K+ + AD ER + I+ + + + E ++
Sbjct: 89 LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQ 148
Query: 3190 AEPA 3193
+ A
Sbjct: 149 LKEA 152
>gi|38348356 testis expressed 9 [Homo sapiens]
Length = 391
Score = 42.0 bits (97), Expect = 0.014
Identities = 46/211 (21%), Positives = 89/211 (42%), Gaps = 27/211 (12%)
Query: 3022 PQEALVSVSRRFIEETKGIEPVHKDSISLFMAHVHTTVNE-MSTRYYQNERRHNYTTPKS 3080
P E +V + +TK I+PV+K L A+ N + +Y + + P+
Sbjct: 92 PSEGIVHLHSETKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSDVQTADDVAIPED 151
Query: 3081 FLEQISLFKNLLK----KKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLASQEAEL-- 3134
F + SL K + K ++ + E + + +G+ T +Q+ LKA+L + EL
Sbjct: 152 FSD-FSLAKTISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDN 210
Query: 3135 -----------------QLRNHDAEALITK--IGLQTEKVSREKTIADAEERKVTAIQTE 3175
Q++N + + + + I +Q +V + KT+ + +K +Q +
Sbjct: 211 VVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQ 270
Query: 3176 VFQKQRECEADLLKAEPALVAATAALNTLNR 3206
+ +RE E + A + +A LNR
Sbjct: 271 LSSVERELENKRRLQKQAASSQSATEVRLNR 301
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 40.8 bits (94), Expect = 0.031
Identities = 30/137 (21%), Positives = 68/137 (49%), Gaps = 16/137 (11%)
Query: 3058 TVNEMSTRYYQNERRHNYTTPKSFLEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTA 3117
++NE+ Y Q + + K ++++ F+ L ++K N V E +E+++ T
Sbjct: 1543 SLNEVLKNYNQQKDIEH----KELVQKLQHFQELGEEKDNRVKEAEEKIL-------TLE 1591
Query: 3118 SQVGDLKARLASQEAELQ-----LRNHDAEALITKIGLQTEKVSREKTIADAEERKVTAI 3172
+QV +KA L +++ EL+ +++ + E + L++E ++ + E+K+ AI
Sbjct: 1592 NQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAI 1651
Query: 3173 QTEVFQKQRECEADLLK 3189
+ ++ + E E K
Sbjct: 1652 KKQLLSQMEEKEEQYKK 1668
>gi|157388975 coiled-coil domain containing 99 [Homo sapiens]
Length = 605
Score = 40.8 bits (94), Expect = 0.031
Identities = 40/161 (24%), Positives = 67/161 (41%), Gaps = 13/161 (8%)
Query: 3035 EETKGIEPVHKDSISLFMAHVH-TTVNEMSTRY--YQNERRHNYTTPKSFLEQISLFKNL 3091
E K + +H + + ++ H VNE+ T+ + E + K Q+ K L
Sbjct: 81 EAIKQQQKMHLEKLEEQLSRSHGQEVNELKTKIEKLKVELDEARLSEKQLKHQVDHQKEL 140
Query: 3092 LKKKQNEVSEKKERLVNGIQK----LKTTASQVGDLKARLASQEAELQLRNHDAEALITK 3147
L K E+ ER+ + L+ +++ +K L + ELQ R E LIT
Sbjct: 141 LSCKSEELRVMSERVQESMSSEMLALQIELTEMESMKTTLKEEVNELQYRQEQLELLITN 200
Query: 3148 IGLQTEKVSREKTIADAEERKVTAIQ-TEVFQKQRECEADL 3187
+ Q +++ EK EER+ A+ +K R DL
Sbjct: 201 LMRQVDRLKEEK-----EEREKEAVSYYNALEKARVANQDL 236
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 40.0 bits (92), Expect = 0.053
Identities = 46/217 (21%), Positives = 97/217 (44%), Gaps = 15/217 (6%)
Query: 3604 QAQTTLLNFTVTEDGLEAQLLAEVVSIERPDLEKLKLVLTKHQNDFKIELKYLEDDLLLR 3663
+AQ L +F V D +++ A V++ D KLK L ++ K ++K ++DL R
Sbjct: 2072 KAQAELASFKVLLDDTQSEA-ARVLA----DNLKLKKELQSNKESVKSQMKQKDEDLERR 2126
Query: 3664 LSAAEGSFLDDTK-LVERLEATKTTVAEIEHKV----IEAKENERKINEARECYRPVAAR 3718
L AE L + K + E+L+A + +E + + + ++++ + +E +
Sbjct: 2127 LEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQ 2186
Query: 3719 ASLLYFVINDLQKINPLYQFSLKAFNVLFHRAIE-QADKVEDMQGRISILMESI----TH 3773
+ ++ LQ K + F AI+ + +++ + S+L + + H
Sbjct: 2187 LAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIH 2246
Query: 3774 AVFLYTSQALFEKDKLTFLSQMAFQILLRKKEIDPLE 3810
L + + E DK + S+ ++ L++K D L+
Sbjct: 2247 MEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQ 2283
Score = 36.6 bits (83), Expect = 0.58
Identities = 27/114 (23%), Positives = 54/114 (47%), Gaps = 8/114 (7%)
Query: 3089 KNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLASQEAELQLRNHDAEALITKI 3148
+N L K ++E+ K++L + L+ Q G+L+ + QEA++Q E L T +
Sbjct: 2304 QNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDL 2363
Query: 3149 GLQTEKVSREKTIADAEERKV--------TAIQTEVFQKQRECEADLLKAEPAL 3194
E SR + +E+K+ AIQ + + +++ + ++ + E L
Sbjct: 2364 QASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLL 2417
Score = 35.8 bits (81), Expect = 0.99
Identities = 72/378 (19%), Positives = 147/378 (38%), Gaps = 61/378 (16%)
Query: 3056 HTTVNEMSTRYYQNERRHNYTTPKSFL-----EQISLFKNLLKKKQNEVSEKKERLVNGI 3110
+T ++++ST+ + + T + L E++S L + + E + +ERL+N +
Sbjct: 1871 NTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQL 1930
Query: 3111 QKLKTTASQVGD--LKARLASQEAELQLRNHDAEALITKIGLQTEKVSREKTIADAEERK 3168
+L + A++ ++ E +++N + ++++ + +++ +EKT ++E RK
Sbjct: 1931 AELNGSIGNYCQDVTDAQIKNELLESEMKN--LKKCVSELEEEKQQLVKEKTKVESEIRK 1988
Query: 3169 VTAIQTEVFQKQRECEADLLKAEPALVAATAALNTLNRVNLSELKAFPNPPIAVTNVTAA 3228
+ + QK EP + L L + E+K I +A
Sbjct: 1989 EYLEKIQGAQK-----------EPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISA 2037
Query: 3229 VMVLLAPRGRVPKDRSWKAAKVFMGKVDDFLQALINYDKEHIPENCLKVVNEHYLKDPE- 3287
+ +R+ KA +F+Q D E EN + V E
Sbjct: 2038 L------------ERTVKAL--------EFVQTESQKDLEITKENLAQAVEHRKKAQAEL 2077
Query: 3288 --FNPNLIRTKSFAAAGLCAWVINIIKFYEVYCDVEPKRQALAQANLELAA--------- 3336
F L T+S AA L N+ E+ + E + + Q + +L
Sbjct: 2078 ASFKVLLDDTQSEAARVLAD---NLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKH 2134
Query: 3337 ------ATEKLEAIRKKLVDLDRNLSRLTASFEKATAEKVRCQEEVNQTNKTIKLANRLV 3390
EKL+A+R++ V L+ + + + K E + QE ++ T + + +
Sbjct: 2135 LKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSM 2194
Query: 3391 KELEAKKIRWGQSIKSFE 3408
L+ + R K +E
Sbjct: 2195 SSLQDDRDRVIDEAKKWE 2212
>gi|223555975 tropomyosin 4 isoform 1 [Homo sapiens]
Length = 284
Score = 39.7 bits (91), Expect = 0.069
Identities = 22/115 (19%), Positives = 53/115 (46%)
Query: 3079 KSFLEQISLFKNLLKKKQNEVSEKKERLVNGIQKLKTTASQVGDLKARLASQEAELQLRN 3138
K E+++ + LK ++E+ + E L + +KL+ T + D + +A+ +QL
Sbjct: 37 KQVEEELTHLQKKLKGTEDELDKYSEDLKDAQEKLELTEKKASDAEGDVAALNRRIQLVE 96
Query: 3139 HDAEALITKIGLQTEKVSREKTIADAEERKVTAIQTEVFQKQRECEADLLKAEPA 3193
+ + ++ +K+ + AD ER + I+ + + + E ++ + A
Sbjct: 97 EELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMEIQEMQLKEA 151
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 39.7 bits (91), Expect = 0.069
Identities = 200/1060 (18%), Positives = 418/1060 (39%), Gaps = 180/1060 (16%)
Query: 723 KLVAVLREVKYLLMLKKQDIPDSALAIFKKRNTILKYIGNLDLLVQGYNKLKQTLLEVEY 782
K A +E++ L+ Q+ D L + + +L D L++ +L+ + EV
Sbjct: 866 KSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTE 925
Query: 783 PLIEDELRAIDEQLTAATTWLTWQDDCWGY---IERVRAATSELEHRVERTQKNVKVIQQ 839
++E I+ +LTA L +D+C I+ + +++E T+ VK + +
Sbjct: 926 RAEDEE--EINAELTAKKRKL--EDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTE 981
Query: 840 TMRGWARCVLPPRREHR------REAAFTL---EDKGDLFTKKYKLIQGDGCKIHNLVEE 890
+ G + RE + ++A L EDK + K ++ + + +E+
Sbjct: 982 ELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQ 1041
Query: 891 NRKLFKANPSLDTWKIYVEFIDDIVVEGFFQAIMHDLDFFLKNTEKQLKPAPFFQAQMIL 950
+KL +D + + D+ + Q + DL+ + +++LK F Q+
Sbjct: 1042 EKKL-----RVDLERNKRKLEGDLKLA---QESILDLENDKQQLDERLKKKDFEYCQL-- 1091
Query: 951 LPPEIVFKPSLDREAGDGFYDLVEEMLCNSFRMSAQMN-----RIATHLEIKNYQNDMDN 1005
K ++ G F ++E+ + ++ R T + +Y +++
Sbjct: 1092 -----QSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEE 1146
Query: 1006 MLGLAEVRQEIMNRVVNVINK----VLDFRNTLETHTYLWVDDRAEFMKHFLLYGHAVSS 1061
+ E + + + + K L R LE T + E M L HA S
Sbjct: 1147 LSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATL-----QHEAMVAALRKKHADSV 1201
Query: 1062 DEMDAHANEEIPEQPPTLEQFKEQIDIYEALYVQMSKFEDFRVFDSWFKVDMKPFKVSLL 1121
E+ EQID + + ++ K + S FK+++ S+
Sbjct: 1202 AELG------------------EQIDNLQRVKQKLEKEK------SEFKLEIDDLSSSME 1237
Query: 1122 TIIKKWSWMFQEHLLRFVIDSLNELQEFIKETDSGLQRELNEGDHDGLVDIMVHLLAVRS 1181
++ K + + E + R + D L+E + +E +QR L+E L +S
Sbjct: 1238 SVSKSKANL--EKICRTLEDQLSEARGKNEE----IQRSLSE------------LTTQKS 1279
Query: 1182 R-QRATDELFEPLKETITLLESYGQKMPEQVYIQ-LEELPERWETTKKIAATVRHEV-SP 1238
R Q EL L+E +++ + +Q + Q EEL + E K + H + S
Sbjct: 1280 RLQTEAGELSRQLEEKESIVSQLSRS--KQAFTQQTEELKRQLEEENKAKNALAHALQSS 1337
Query: 1239 LHNAEVTLIRKKCILFDAKQAEFRERFRHYAPLGFNAENPY-TALDKANEELEALEEEML 1297
H+ + L+R++ +AE + Y T + EELE ++++
Sbjct: 1338 RHDCD--LLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA 1395
Query: 1298 Q-MQESTRLFEVALPEYKQMKQCRKEIKLLKGLWDVIIYVRRSIDNWTKTQWRQIHVEQM 1356
Q +Q+S E + +++ ++ +L + D+++ V R+ +Q + +++
Sbjct: 1396 QRLQDSEEQVEAVNAKCASLEKTKQ--RLQGEVEDLMVDVERANSLAAALDKKQRNFDKV 1453
Query: 1357 DVELRRFAKAS------SITEIWSLNKEV-RVWDAYT--------------GLEGTVKDM 1395
E + + S S+ E SL+ E+ ++ +AY LE + D+
Sbjct: 1454 LAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADL 1513
Query: 1396 TASL----RAITELQSPALRDRHWHQLMKAIGVKFLINEATTLADLLALRLHRVEDDVRR 1451
T + + I EL+ + R +L KA ++ + EA + ++ R++ ++ +
Sbjct: 1514 TEQIAENGKTIHELE----KSRKQIELEKA-DIQLALEEAEAALEHEEAKILRIQLELTQ 1568
Query: 1452 I---VDKAV--KELGTEKVITEISQTWATMKFSYEVHYRTGIPLLKSDEQLFETLEHNQV 1506
+ +D+ + K+ E++ +T TM+ + + R+ ++ +++ L N++
Sbjct: 1569 VKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDL--NEI 1626
Query: 1507 QLQTLLQSKYVEYFIEQVLSWQNKLNIADLVIFTWMEVQRTWSHLESIFVCSEDIRIQLV 1566
++Q ++ ++ + S Q +L L HL+ ED++ QL
Sbjct: 1627 EIQLSHANRQAAETLKHLRSVQGQLKDTQL-------------HLDDALRGQEDLKEQLA 1673
Query: 1567 KDARRFDGVDAEFKELMFKTAKVENVLEATCRPNLYEKLKDLQSRLSLCEKALAEYLETK 1626
RR + + AE +EL + E R ++L D R+ L + TK
Sbjct: 1674 IVERRANLLQAEVEELRATLEQTER-----ARKLAEQELLDSNERVQLLHTQNTSLIHTK 1728
Query: 1627 RIAFPRFYFVSSADLLDILSKGAQPKQVTCHLAKLFDSIADLQFEDNQDVSAHRAVGMYS 1686
+ DL+ + S ++ D+ D + + + A M +
Sbjct: 1729 K--------KLETDLMQLQS-------------EVEDASRDARNAEEKAKKAITDAAMMA 1767
Query: 1687 KEKEYVPFQAECECVGHVETWLLQLEQTMQETVRHSITEA 1726
+E + E + H+E LEQT+++ ++H + EA
Sbjct: 1768 EE-----LKKEQDTSAHLERMKKNLEQTVKD-LQHRLDEA 1801
Score = 33.5 bits (75), Expect = 4.9
Identities = 26/113 (23%), Positives = 54/113 (47%), Gaps = 7/113 (6%)
Query: 3315 EVYCDVEPKRQALAQANLELAAATEKLEAIRKKLVDLDRNLSRLTA-------SFEKATA 3367
E+ D++ LA+ E A K++ + ++L LD +++LT + ++A
Sbjct: 950 ELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALD 1009
Query: 3368 EKVRCQEEVNQTNKTIKLANRLVKELEAKKIRWGQSIKSFEAQEKTLCGDVLL 3420
+ +++VN NKT + V++LE+ + + E ++ L GD+ L
Sbjct: 1010 DLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKL 1062
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 162,068,640
Number of Sequences: 37866
Number of extensions: 7108264
Number of successful extensions: 21849
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 46
Number of HSP's successfully gapped in prelim test: 117
Number of HSP's that attempted gapping in prelim test: 20049
Number of HSP's gapped (non-prelim): 1536
length of query: 4523
length of database: 18,247,518
effective HSP length: 123
effective length of query: 4400
effective length of database: 13,590,000
effective search space: 59796000000
effective search space used: 59796000000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 73 (32.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.