Search of human proteins with 51317366

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|51317366 myosin XVIIIB [Homo sapiens]
         (2567 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|51317366 myosin XVIIIB [Homo sapiens]                             5053   0.0  
gi|42794779 myosin 18A isoform b [Homo sapiens]                      1385   0.0  
gi|28416946 myosin 18A isoform a [Homo sapiens]                      1385   0.0  
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...   422   e-117
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...   422   e-117
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...   419   e-116
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...   419   e-116
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]   412   e-114
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]    400   e-110
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]          374   e-103
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...   372   e-102
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...   372   e-102
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]          372   e-102
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ...   371   e-102
gi|156104908 myosin heavy chain 6 [Homo sapiens]                      370   e-102
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]          369   e-101
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]              368   e-101
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...   368   e-101
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo...   368   e-101
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ...   367   e-101
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...   363   2e-99
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...   360   8e-99
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...   355   4e-97
gi|215982794 myosin VA isoform 2 [Homo sapiens]                       232   3e-60
gi|215982791 myosin VA isoform 1 [Homo sapiens]                       229   2e-59
gi|153945715 myosin VC [Homo sapiens]                                 219   2e-56
gi|122937345 myosin VB [Homo sapiens]                                 214   1e-54
gi|154354979 myosin X [Homo sapiens]                                  209   4e-53
gi|189083802 myosin VIIA isoform 2 [Homo sapiens]                     191   6e-48
gi|189083800 myosin VIIA isoform 3 [Homo sapiens]                     191   6e-48

>gi|51317366 myosin XVIIIB [Homo sapiens]
          Length = 2567

 Score = 5053 bits (13106), Expect = 0.0
 Identities = 2567/2567 (100%), Positives = 2567/2567 (100%)

Query: 1    MAISSRLALWEQKIREEDKSPPPSSPPPLFSVIPGGFIKQLVRGTEKEAKEARQRKQLAV 60
            MAISSRLALWEQKIREEDKSPPPSSPPPLFSVIPGGFIKQLVRGTEKEAKEARQRKQLAV
Sbjct: 1    MAISSRLALWEQKIREEDKSPPPSSPPPLFSVIPGGFIKQLVRGTEKEAKEARQRKQLAV 60

Query: 61   ASPEREIPEISISQPNSKSSSGTRSGSQQISQDDQSSSPGSSDILGKESEGSRSPDPEQM 120
            ASPEREIPEISISQPNSKSSSGTRSGSQQISQDDQSSSPGSSDILGKESEGSRSPDPEQM
Sbjct: 61   ASPEREIPEISISQPNSKSSSGTRSGSQQISQDDQSSSPGSSDILGKESEGSRSPDPEQM 120

Query: 121  TSINGEKAQELGSSATPTKKTVPFKRGVRRGDVLLMVAKLDPDSAKPEKTHPHDAPPCKT 180
            TSINGEKAQELGSSATPTKKTVPFKRGVRRGDVLLMVAKLDPDSAKPEKTHPHDAPPCKT
Sbjct: 121  TSINGEKAQELGSSATPTKKTVPFKRGVRRGDVLLMVAKLDPDSAKPEKTHPHDAPPCKT 180

Query: 181  SPPATDTGKEKKGETSRTPCGSQASTEILAPKAEKTRTGGLGDPGQGTVALKKGEEGQSI 240
            SPPATDTGKEKKGETSRTPCGSQASTEILAPKAEKTRTGGLGDPGQGTVALKKGEEGQSI
Sbjct: 181  SPPATDTGKEKKGETSRTPCGSQASTEILAPKAEKTRTGGLGDPGQGTVALKKGEEGQSI 240

Query: 241  VGKGLGTPKTTELKEAEPQGKDRQGTRPQAQGPGEGVRPGKAEKEGAEPTNTVEKGNVSK 300
            VGKGLGTPKTTELKEAEPQGKDRQGTRPQAQGPGEGVRPGKAEKEGAEPTNTVEKGNVSK
Sbjct: 241  VGKGLGTPKTTELKEAEPQGKDRQGTRPQAQGPGEGVRPGKAEKEGAEPTNTVEKGNVSK 300

Query: 301  DVGSEGKHVRPQIPGRKWGGFLGRRSKWDGPQNKKDKEGVLLSKAEKTGEPQTQMEKTSQ 360
            DVGSEGKHVRPQIPGRKWGGFLGRRSKWDGPQNKKDKEGVLLSKAEKTGEPQTQMEKTSQ
Sbjct: 301  DVGSEGKHVRPQIPGRKWGGFLGRRSKWDGPQNKKDKEGVLLSKAEKTGEPQTQMEKTSQ 360

Query: 361  VQGELGDDLRMGEKAGELRSTTGKAGESWDKKEKMGQPQGKSGNAGEARSQTEKGCEAPK 420
            VQGELGDDLRMGEKAGELRSTTGKAGESWDKKEKMGQPQGKSGNAGEARSQTEKGCEAPK
Sbjct: 361  VQGELGDDLRMGEKAGELRSTTGKAGESWDKKEKMGQPQGKSGNAGEARSQTEKGCEAPK 420

Query: 421  EVSTMVESPAAPGKGGWPGSRGQEAEEPCSRAGDGAGALETELEGPSQPALEKDAERPRI 480
            EVSTMVESPAAPGKGGWPGSRGQEAEEPCSRAGDGAGALETELEGPSQPALEKDAERPRI
Sbjct: 421  EVSTMVESPAAPGKGGWPGSRGQEAEEPCSRAGDGAGALETELEGPSQPALEKDAERPRI 480

Query: 481  RKENQDGPAPQEEGKGGQSRDSDQAPEDRWYEAEKVWLAQKDGFTLATVLKPDEGTADLP 540
            RKENQDGPAPQEEGKGGQSRDSDQAPEDRWYEAEKVWLAQKDGFTLATVLKPDEGTADLP
Sbjct: 481  RKENQDGPAPQEEGKGGQSRDSDQAPEDRWYEAEKVWLAQKDGFTLATVLKPDEGTADLP 540

Query: 541  AGRVRLWIDADKTITEVDEEHVHRANPPELDQVEDLASLISVNESSVLNTLLQRYKAQLL 600
            AGRVRLWIDADKTITEVDEEHVHRANPPELDQVEDLASLISVNESSVLNTLLQRYKAQLL
Sbjct: 541  AGRVRLWIDADKTITEVDEEHVHRANPPELDQVEDLASLISVNESSVLNTLLQRYKAQLL 600

Query: 601  HTCTGPDLIVLQPRGPSVPSAGKVPKGRRDGLPAHIGSMAQRAYWALLNQRRDQSIVALG 660
            HTCTGPDLIVLQPRGPSVPSAGKVPKGRRDGLPAHIGSMAQRAYWALLNQRRDQSIVALG
Sbjct: 601  HTCTGPDLIVLQPRGPSVPSAGKVPKGRRDGLPAHIGSMAQRAYWALLNQRRDQSIVALG 660

Query: 661  WSGAGKTTCCEQVLEHLVGMAGSVDGRVSVEKIRATFTVLRAFGSVSMAHSRSATRFSMV 720
            WSGAGKTTCCEQVLEHLVGMAGSVDGRVSVEKIRATFTVLRAFGSVSMAHSRSATRFSMV
Sbjct: 661  WSGAGKTTCCEQVLEHLVGMAGSVDGRVSVEKIRATFTVLRAFGSVSMAHSRSATRFSMV 720

Query: 721  MSLDFNATGRITAAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTELNLHQMA 780
            MSLDFNATGRITAAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTELNLHQMA
Sbjct: 721  MSLDFNATGRITAAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTELNLHQMA 780

Query: 781  DSSSFGMGVWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAAGACK 840
            DSSSFGMGVWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAAGACK
Sbjct: 781  DSSSFGMGVWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAAGACK 840

Query: 841  VGRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWGLEDEETSSGL 900
            VGRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWGLEDEETSSGL
Sbjct: 841  VGRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWGLEDEETSSGL 900

Query: 901  KMTGVDCVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQGKDRA 960
            KMTGVDCVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQGKDRA
Sbjct: 901  KMTGVDCVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQGKDRA 960

Query: 961  ATFEELCHNYAHERLQLLFYQRTFVSTLQRYQEEGVPVQFDLPDPSPGTTVAVVDQNPSQ 1020
            ATFEELCHNYAHERLQLLFYQRTFVSTLQRYQEEGVPVQFDLPDPSPGTTVAVVDQNPSQ
Sbjct: 961  ATFEELCHNYAHERLQLLFYQRTFVSTLQRYQEEGVPVQFDLPDPSPGTTVAVVDQNPSQ 1020

Query: 1021 VRLPAGGGAQDARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTEGSSALRTCEQP 1080
            VRLPAGGGAQDARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTEGSSALRTCEQP
Sbjct: 1021 VRLPAGGGAQDARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTEGSSALRTCEQP 1080

Query: 1081 LQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSLFQARAKLPPVC 1140
            LQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSLFQARAKLPPVC
Sbjct: 1081 LQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSLFQARAKLPPVC 1140

Query: 1141 RAVAGLEGTSQQALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMDALTSMIKRSRLHFIH 1200
            RAVAGLEGTSQQALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMDALTSMIKRSRLHFIH
Sbjct: 1141 RAVAGLEGTSQQALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMDALTSMIKRSRLHFIH 1200

Query: 1201 CLVPNPVVESRSGQESPPPPQPGRDKPGAGGPLALDIPALRVQLAGFHILEALRLHRTGY 1260
            CLVPNPVVESRSGQESPPPPQPGRDKPGAGGPLALDIPALRVQLAGFHILEALRLHRTGY
Sbjct: 1201 CLVPNPVVESRSGQESPPPPQPGRDKPGAGGPLALDIPALRVQLAGFHILEALRLHRTGY 1260

Query: 1261 ADHMGLTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLETLDLEKKAVAVGHSQVFL 1320
            ADHMGLTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLETLDLEKKAVAVGHSQVFL
Sbjct: 1261 ADHMGLTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLETLDLEKKAVAVGHSQVFL 1320

Query: 1321 KAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKNVAVFLAVK 1380
            KAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKNVAVFLAVK
Sbjct: 1321 KAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKNVAVFLAVK 1380

Query: 1381 DWPWWQLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIA 1440
            DWPWWQLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIA
Sbjct: 1381 DWPWWQLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIA 1440

Query: 1441 DLTSDLADERFKGDVACQVLESERAERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQ 1500
            DLTSDLADERFKGDVACQVLESERAERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQ
Sbjct: 1441 DLTSDLADERFKGDVACQVLESERAERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQ 1500

Query: 1501 KIQLNDLERNPTGGADEWQMRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGEL 1560
            KIQLNDLERNPTGGADEWQMRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGEL
Sbjct: 1501 KIQLNDLERNPTGGADEWQMRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGEL 1560

Query: 1561 QSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGES 1620
            QSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGES
Sbjct: 1561 QSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGES 1620

Query: 1621 VFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGE 1680
            VFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGE
Sbjct: 1621 VFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGE 1680

Query: 1681 NCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQE 1740
            NCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQE
Sbjct: 1681 NCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQE 1740

Query: 1741 EELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRL 1800
            EELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRL
Sbjct: 1741 EELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRL 1800

Query: 1801 RRDLRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTAD 1860
            RRDLRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTAD
Sbjct: 1801 RRDLRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTAD 1860

Query: 1861 LESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAAD 1920
            LESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAAD
Sbjct: 1861 LESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAAD 1920

Query: 1921 IGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQEAVICDLENKTE 1980
            IGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQEAVICDLENKTE
Sbjct: 1921 IGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQEAVICDLENKTE 1980

Query: 1981 FQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQYYQRRLEELKADMEELVQ 2040
            FQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQYYQRRLEELKADMEELVQ
Sbjct: 1981 FQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQYYQRRLEELKADMEELVQ 2040

Query: 2041 REAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSDSDTESVQTA 2100
            REAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSDSDTESVQTA
Sbjct: 2041 REAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSDSDTESVQTA 2100

Query: 2101 VDCGSSGRKEMDNVSILSSQPEGSLQSWLSCTLSLATDTMRTPSRQSATSSRILSPRINE 2160
            VDCGSSGRKEMDNVSILSSQPEGSLQSWLSCTLSLATDTMRTPSRQSATSSRILSPRINE
Sbjct: 2101 VDCGSSGRKEMDNVSILSSQPEGSLQSWLSCTLSLATDTMRTPSRQSATSSRILSPRINE 2160

Query: 2161 EAGDTERTQSALALSRARSTNVHSKTSGDKPVSPHFVRRQKYCHFGDGEVLAVQRKSTER 2220
            EAGDTERTQSALALSRARSTNVHSKTSGDKPVSPHFVRRQKYCHFGDGEVLAVQRKSTER
Sbjct: 2161 EAGDTERTQSALALSRARSTNVHSKTSGDKPVSPHFVRRQKYCHFGDGEVLAVQRKSTER 2220

Query: 2221 LEPASSPLASRSTNTSPLSREKLPSPSAALSEFVEGLRRKRAQRGQGSTLGLEDWPTLPI 2280
            LEPASSPLASRSTNTSPLSREKLPSPSAALSEFVEGLRRKRAQRGQGSTLGLEDWPTLPI
Sbjct: 2221 LEPASSPLASRSTNTSPLSREKLPSPSAALSEFVEGLRRKRAQRGQGSTLGLEDWPTLPI 2280

Query: 2281 YQTTGASTLRRGRAGSDEGNLSLRVGAKSPLEIEGAAGGLLRSTSLKCISSDGVGGTTLL 2340
            YQTTGASTLRRGRAGSDEGNLSLRVGAKSPLEIEGAAGGLLRSTSLKCISSDGVGGTTLL
Sbjct: 2281 YQTTGASTLRRGRAGSDEGNLSLRVGAKSPLEIEGAAGGLLRSTSLKCISSDGVGGTTLL 2340

Query: 2341 PEKSKTQFSSCESLLESRPSMGRKLSSPTTPRDMLLSPTLRPRRRCLESSVDDAGCPDLG 2400
            PEKSKTQFSSCESLLESRPSMGRKLSSPTTPRDMLLSPTLRPRRRCLESSVDDAGCPDLG
Sbjct: 2341 PEKSKTQFSSCESLLESRPSMGRKLSSPTTPRDMLLSPTLRPRRRCLESSVDDAGCPDLG 2400

Query: 2401 KEPLVFQNRQFAHLMEEPLGSDPFSWKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGS 2460
            KEPLVFQNRQFAHLMEEPLGSDPFSWKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGS
Sbjct: 2401 KEPLVFQNRQFAHLMEEPLGSDPFSWKLPSLDYERKTKVDFDDFLPAIRKPQTPTSLAGS 2460

Query: 2461 AKGGQDGSQRSSIHFETEEANRSFLSGIKTILKKSPEPKEDPAHLSDSSSSSGSIVSFKS 2520
            AKGGQDGSQRSSIHFETEEANRSFLSGIKTILKKSPEPKEDPAHLSDSSSSSGSIVSFKS
Sbjct: 2461 AKGGQDGSQRSSIHFETEEANRSFLSGIKTILKKSPEPKEDPAHLSDSSSSSGSIVSFKS 2520

Query: 2521 ADSIKSRPGIPRLAGDGGERTSPERREPGTGRKDDDVASIMKKYLQK 2567
            ADSIKSRPGIPRLAGDGGERTSPERREPGTGRKDDDVASIMKKYLQK
Sbjct: 2521 ADSIKSRPGIPRLAGDGGERTSPERREPGTGRKDDDVASIMKKYLQK 2567


>gi|42794779 myosin 18A isoform b [Homo sapiens]
          Length = 2039

 Score = 1385 bits (3584), Expect = 0.0
 Identities = 756/1671 (45%), Positives = 1131/1671 (67%), Gaps = 44/1671 (2%)

Query: 485  QDGPAPQEEGKGGQSRDSDQAPEDRWYEAEKVWLAQKDGFTLATVLKPDEGTADLPAGRV 544
            + G  P+ E    ++ +   A E+ W E EKVWL  +DGF+LA+ LK +E   +LP G+V
Sbjct: 322  RSGEGPRREPSDAKTEEQIAA-EEAWNETEKVWLVHRDGFSLASQLKSEE--LNLPEGKV 378

Query: 545  RLWIDADKTITEVDEEHVHRANPPELDQVEDLASLISVNESSVLNTLLQRYKAQLLHTCT 604
            R+ +D D  I +VDE+ V +AN P  D++EDLASL+ +NESSVL+TL QRY A LLHT  
Sbjct: 379  RVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYA 438

Query: 605  GPDLIVLQPRGPSVPSAGKVP---KG-RRDGLPAHIGSMAQRAYWALLNQRRDQSIVALG 660
            GP L+VL PRG     + KV    KG RR+ +  HI ++AQ AY A+L  R+DQSI+ LG
Sbjct: 439  GPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLG 498

Query: 661  WSGAGKTTCCEQVLEHLVGMAGSVDGRV-SVEKIRATFTVLRAFGSVSMAHSRSATRFSM 719
             SG+GKTT C+ ++++L  +AG    +V SVEK +A +T+L AFG+     + +ATRFS 
Sbjct: 499  SSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALYTLLEAFGNSPTIINGNATRFSQ 558

Query: 720  VMSLDFNATGRITAAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTELNLHQM 779
            ++SLDF+  G++ +A +QTMLLEK RVAR+P  E+ F VF  +LA  D  LRTEL+L+ +
Sbjct: 559  ILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHL 618

Query: 780  ADSSSFGMGVWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAAGAC 839
            A+++ FG+   +KPE+KQKAA  F++LQ AM++LGIS  EQ+A W +LAAIYHLGAAGA 
Sbjct: 619  AENNVFGIVPLAKPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGAT 678

Query: 840  K----VGRKQFMRFEWANYAAEALGCEYEELNTATFKH-HLRQIIQQMTF---GPSRWGL 891
            K     GRKQF R EWA  AA  LGC  EEL++A FKH H    +Q+ T    GP   GL
Sbjct: 679  KEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGTLQRSTSFRQGPEESGL 738

Query: 892  EDEETSSGLKMTGVDCVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQN 951
             D    +G K++ ++C+EGMA+GLY ELF  +VSL+NR+  S   S+ S+M+VD+PGFQN
Sbjct: 739  GD---GTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMMIVDTPGFQN 795

Query: 952  PRHQGKDRAATFEELCHNYAHERLQLLFYQRTFVSTLQRYQEEGVPVQFDLPDPSPGTTV 1011
            P   G  R A+FEELCHNY  +RLQ LF++RTFV  L+RY+EE + + FD  +P    +V
Sbjct: 796  PEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSV 855

Query: 1012 AVVDQNPSQVRLPAGGGAQDARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTEGS 1071
            A VDQ   Q  + +     +ARGL W+L+EE  V G+S+  +LERL + +  +    +G 
Sbjct: 856  AAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQ 915

Query: 1072 SALRTCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSLFQ 1131
            S L    +P    + H  G + V Y++TGWL+  K N +  +AP++L  S+++ + +LF 
Sbjct: 916  SPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFL 975

Query: 1132 ARAKLPPVCR-AVAGLEGTSQQALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMDALTSM 1190
             RA    V   ++AGLEG SQ AL+R+  +R+TF + +AAV++K+ C Q+KLQ+DAL   
Sbjct: 976  GRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDT 1035

Query: 1191 IKRSRLHFIHCLVPNP---VVESRSGQESPPPPQPGRDKPGA----GGPLALDIPALRVQ 1243
            IK+S+LHF+HC +P       E RS            D P       G L LD+P LR Q
Sbjct: 1036 IKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQ 1095

Query: 1244 LAGFHILEALRLHRTGYADHMGLTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLET 1303
            L G  +L+A+R++R GY DHM  + FRR+F VL   L KK       +DER+AVEELLE 
Sbjct: 1096 LRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLEC 1155

Query: 1304 LDLEKKAVAVGHSQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIRR 1363
            LDLEK +  +G S+VF +AG ++RLE+QR++  S+++ LFQAAC+G+L+RQ FKK KI+ 
Sbjct: 1156 LDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQD 1215

Query: 1364 LAAQCIQKNVAVFLAVKDWPWWQLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEK 1423
            LA +C+QKN+     VKDWPWW+L  +++PL+   +  EQ+R K+EE+  LR KLEK+EK
Sbjct: 1216 LAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEK 1275

Query: 1424 LRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESERAERLQAFREVQELKSKHEQ 1483
             RNELR N+D LES+I++LTS+L DER  G+ A Q+L++E AERL+A +E++EL+++++ 
Sbjct: 1276 ERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDA 1335

Query: 1484 VQKKLGDVNKQLEEAQ--QKIQLN-DLERNPTGGADEWQMRFDCAQMENEFLRKRLQQ-C 1539
            ++K++  +  ++ EA+  +  ++N +++ +  GG  EW+++++ A  E +F +KRLQQ  
Sbjct: 1336 LKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGG--EWRLKYERAVREVDFTKKRLQQEF 1393

Query: 1540 EERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRN 1599
            E++L+ E   +++LE++LG+LQ+  + +++   QLK+KC  LT +L+DT + LE QQ RN
Sbjct: 1394 EDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRN 1453

Query: 1600 HELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEASQLK 1659
            HELEKKQ++FD +L+QA  E+  EK  REK+ +E   +  E   L+QQL++K+ + +   
Sbjct: 1454 HELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFT 1513

Query: 1660 QQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQ 1719
            Q+V  L+   +++    S  E  +A +K++L  LE+   +Q++   +Q  TI+ LEQ + 
Sbjct: 1514 QKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKL 1573

Query: 1720 RFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLE 1779
            R E+E+ERM+Q H K+ E ++EE+E+ RQSCQK+L Q+E+QLE+EYE+KQ VL EK++LE
Sbjct: 1574 RLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELE 1633

Query: 1780 GLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQ 1839
            G + TL DQ+  RDF+ EKRLR+DL+RT ALL+D QL+L  +++  ++ SK E+ ++ +Q
Sbjct: 1634 GKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKN--SAPSKREIAQLKNQ 1691

Query: 1840 LEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDED 1899
            LE+SE  C  A+K +K +  ++E +H +++++ + K+ ++EQL RLQ EK ++  R++ED
Sbjct: 1692 LEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEED 1751

Query: 1900 QDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQST 1959
            Q+D+NELM+KHK  +AQ++ D+ QI +LQ QLEEA KEK +LQE+LQ  Q ++E+LEQS 
Sbjct: 1752 QEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSM 1811

Query: 1960 VDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRE 2019
            VD+++VSRQEA I +LE + EF++ Q+KR E L  RL++++ K+ EE  Q   +E++++E
Sbjct: 1812 VDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKE 1871

Query: 2020 SSQYYQRRLEELKADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIAD 2079
             ++  QR+L + K +M EL ++EAEASR+  ELE  +E L A  Q+LQ DL+ + +RI D
Sbjct: 1872 QNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGD 1931

Query: 2080 LQAALEEVASSDSDTESVQTAVDCGSSGRKEMDNVSILSSQPEGSLQSWLS 2130
            LQAA+E+   SD + + +       S G  ++D  S L  + +G ++SWLS
Sbjct: 1932 LQAAIEDEMESDENEDLI------NSEGDSDVD--SELEDRVDG-VKSWLS 1973


>gi|28416946 myosin 18A isoform a [Homo sapiens]
          Length = 2054

 Score = 1385 bits (3584), Expect = 0.0
 Identities = 756/1677 (45%), Positives = 1133/1677 (67%), Gaps = 41/1677 (2%)

Query: 485  QDGPAPQEEGKGGQSRDSDQAPEDRWYEAEKVWLAQKDGFTLATVLKPDEGTADLPAGRV 544
            + G  P+ E    ++ +   A E+ W E EKVWL  +DGF+LA+ LK +E   +LP G+V
Sbjct: 322  RSGEGPRREPSDAKTEEQIAA-EEAWNETEKVWLVHRDGFSLASQLKSEE--LNLPEGKV 378

Query: 545  RLWIDADKTITEVDEEHVHRANPPELDQVEDLASLISVNESSVLNTLLQRYKAQLLHTCT 604
            R+ +D D  I +VDE+ V +AN P  D++EDLASL+ +NESSVL+TL QRY A LLHT  
Sbjct: 379  RVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYA 438

Query: 605  GPDLIVLQPRGPSVPSAGKVP---KG-RRDGLPAHIGSMAQRAYWALLNQRRDQSIVALG 660
            GP L+VL PRG     + KV    KG RR+ +  HI ++AQ AY A+L  R+DQSI+ LG
Sbjct: 439  GPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLG 498

Query: 661  WSGAGKTTCCEQVLEHLVGMAGSVDGRV-SVEKIRATFTVLRAFGSVSMAHSRSATRFSM 719
             SG+GKTT C+ ++++L  +AG    +V SVEK +A +T+L AFG+     + +ATRFS 
Sbjct: 499  SSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALYTLLEAFGNSPTIINGNATRFSQ 558

Query: 720  VMSLDFNATGRITAAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTELNLHQM 779
            ++SLDF+  G++ +A +QTMLLEK RVAR+P  E+ F VF  +LA  D  LRTEL+L+ +
Sbjct: 559  ILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHL 618

Query: 780  ADSSSFGMGVWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAAGAC 839
            A+++ FG+   +KPE+KQKAA  F++LQ AM++LGIS  EQ+A W +LAAIYHLGAAGA 
Sbjct: 619  AENNVFGIVPLAKPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGAT 678

Query: 840  K----VGRKQFMRFEWANYAAEALGCEYEELNTATFKH-HLRQIIQQMTF---GPSRWGL 891
            K     GRKQF R EWA  AA  LGC  EEL++A FKH H    +Q+ T    GP   GL
Sbjct: 679  KEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGTLQRSTSFRQGPEESGL 738

Query: 892  EDEETSSGLKMTGVDCVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQN 951
             D    +G K++ ++C+EGMA+GLY ELF  +VSL+NR+  S   S+ S+M+VD+PGFQN
Sbjct: 739  GD---GTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMMIVDTPGFQN 795

Query: 952  PRHQGKDRAATFEELCHNYAHERLQLLFYQRTFVSTLQRYQEEGVPVQFDLPDPSPGTTV 1011
            P   G  R A+FEELCHNY  +RLQ LF++RTFV  L+RY+EE + + FD  +P    +V
Sbjct: 796  PEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSV 855

Query: 1012 AVVDQNPSQVRLPAGGGAQDARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTEGS 1071
            A VDQ   Q  + +     +ARGL W+L+EE  V G+S+  +LERL + +  +    +G 
Sbjct: 856  AAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQ 915

Query: 1072 SALRTCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSLFQ 1131
            S L    +P    + H  G + V Y++TGWL+  K N +  +AP++L  S+++ + +LF 
Sbjct: 916  SPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFL 975

Query: 1132 ARAKLPPVCR-AVAGLEGTSQQALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMDALTSM 1190
             RA    V   ++AGLEG SQ AL+R+  +R+TF + +AAV++K+ C Q+KLQ+DAL   
Sbjct: 976  GRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDT 1035

Query: 1191 IKRSRLHFIHCLVPNP---VVESRSGQESPPPPQPGRDKPGA----GGPLALDIPALRVQ 1243
            IK+S+LHF+HC +P       E RS            D P       G L LD+P LR Q
Sbjct: 1036 IKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQ 1095

Query: 1244 LAGFHILEALRLHRTGYADHMGLTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLET 1303
            L G  +L+A+R++R GY DHM  + FRR+F VL   L KK       +DER+AVEELLE 
Sbjct: 1096 LRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLEC 1155

Query: 1304 LDLEKKAVAVGHSQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIRR 1363
            LDLEK +  +G S+VF +AG ++RLE+QR++  S+++ LFQAAC+G+L+RQ FKK KI+ 
Sbjct: 1156 LDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQD 1215

Query: 1364 LAAQCIQKNVAVFLAVKDWPWWQLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEK 1423
            LA +C+QKN+     VKDWPWW+L  +++PL+   +  EQ+R K+EE+  LR KLEK+EK
Sbjct: 1216 LAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEK 1275

Query: 1424 LRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESERAERLQAFREVQELKSKHEQ 1483
             RNELR N+D LES+I++LTS+L DER  G+ A Q+L++E AERL+A +E++EL+++++ 
Sbjct: 1276 ERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDA 1335

Query: 1484 VQKKLGDVNKQLEEAQ--QKIQLN-DLERNPTGGADEWQMRFDCAQMENEFLRKRLQQ-C 1539
            ++K++  +  ++ EA+  +  ++N +++ +  GG  EW+++++ A  E +F +KRLQQ  
Sbjct: 1336 LKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGG--EWRLKYERAVREVDFTKKRLQQEF 1393

Query: 1540 EERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRN 1599
            E++L+ E   +++LE++LG+LQ+  + +++   QLK+KC  LT +L+DT + LE QQ RN
Sbjct: 1394 EDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRN 1453

Query: 1600 HELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEASQLK 1659
            HELEKKQ++FD +L+QA  E+  EK  REK+ +E   +  E   L+QQL++K+ + +   
Sbjct: 1454 HELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFT 1513

Query: 1660 QQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQ 1719
            Q+V  L+   +++    S  E  +A +K++L  LE+   +Q++   +Q  TI+ LEQ + 
Sbjct: 1514 QKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKL 1573

Query: 1720 RFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLE 1779
            R E+E+ERM+Q H K+ E ++EE+E+ RQSCQK+L Q+E+QLE+EYE+KQ VL EK++LE
Sbjct: 1574 RLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELE 1633

Query: 1780 GLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQ 1839
            G + TL DQ+  RDF+ EKRLR+DL+RT ALL+D QL+L  +++  ++ SK E+ ++ +Q
Sbjct: 1634 GKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKN--SAPSKREIAQLKNQ 1691

Query: 1840 LEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDED 1899
            LE+SE  C  A+K +K +  ++E +H +++++ + K+ ++EQL RLQ EK ++  R++ED
Sbjct: 1692 LEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEED 1751

Query: 1900 QDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQST 1959
            Q+D+NELM+KHK  +AQ++ D+ QI +LQ QLEEA KEK +LQE+LQ  Q ++E+LEQS 
Sbjct: 1752 QEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSM 1811

Query: 1960 VDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRE 2019
            VD+++VSRQEA I +LE + EF++ Q+KR E L  RL++++ K+ EE  Q   +E++++E
Sbjct: 1812 VDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKE 1871

Query: 2020 SSQYYQRRLEELKADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIAD 2079
             ++  QR+L + K +M EL ++EAEASR+  ELE  +E L A  Q+LQ DL+ + +RI D
Sbjct: 1872 QNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGD 1931

Query: 2080 LQAALEEVASSDSDTE---SVQTAVDCGSSGRKEMDNVSILSSQPE---GSLQSWLS 2130
            LQAA+E+   SD + +   S+Q  V      + +++  S + S+ E     ++SWLS
Sbjct: 1932 LQAAIEDEMESDENEDLINSLQDMVTKYQKRKNKLEGDSDVDSELEDRVDGVKSWLS 1988


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score =  422 bits (1085), Expect = e-117
 Identities = 410/1652 (24%), Positives = 764/1652 (46%), Gaps = 222/1652 (13%)

Query: 510  WYEAEKVWL-AQKDGFTLATVL--KPDEGTADLPAGRVRLWIDADKTITEVDEEHVHRAN 566
            W     VW+ ++K GF  A++   K DE   +L        ++  K +T V ++ + + N
Sbjct: 30   WAAKRLVWVPSEKQGFEAASIKEEKGDEVVVEL--------VENGKKVT-VGKDDIQKMN 80

Query: 567  PPELDQVEDLASLISVNESSVLNTLLQRYKAQLLHTCTGPDLIVLQPRGPSVPSAGKVP- 625
            PP+  +VED+A L  +NE+SVL+ L +RY + L++T +G   +V+ P       + K+  
Sbjct: 81   PPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVD 140

Query: 626  --KGR-RDGLPAHIGSMAQRAYWALLNQRRDQSIVALGWSGAGKTTCCEQVLEHLVGMAG 682
              KG+ R  +P HI ++A  AY ++L  R DQSI+  G SGAGKT   ++V+++L  +A 
Sbjct: 141  MYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200

Query: 683  S--------VDGRVSVEKIRATFTVLRAFGSVSMAHSRSATRFSMVMSLDFNATGRITAA 734
            S        + G +  + ++A   +L AFG+     + +++RF   + ++F+ TG I  A
Sbjct: 201  SHKGKKDTSITGELEKQLLQAN-PILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGA 259

Query: 735  QLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTELNLHQMADSSSFGMGVWSKPE 794
             ++T LLEKSR  RQ   E  F +F  M+AG    +R++L L    + +    G    P 
Sbjct: 260  NIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPA 319

Query: 795  DKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAAGACKVGRKQFMRFEWANY 854
             +      F +   AM ++G SE EQ ++ +V++++  LG     K  R         N 
Sbjct: 320  AQDDEM--FQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNI-VFKKERNTDQASMPDNT 376

Query: 855  AAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWGLEDEETSSGLKMTGVDCVEGMASG 914
            AA+ + C    +N   F   +  +  ++  G       D    +  K      VE +A  
Sbjct: 377  AAQKV-CHLMGINVTDFTRSI--LTPRIKVG------RDVVQKAQTKEQADFAVEALAKA 427

Query: 915  LYQELFAAVVSLINRSFSSHHLSMASIM-VVDSPGFQNPRHQGKDRAATFEELCHNYAHE 973
             Y+ LF  +++ +N++    H   AS + ++D  GF+           +FE+LC NY +E
Sbjct: 428  TYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEI------FEVNSFEQLCINYTNE 481

Query: 974  RLQLLFYQRTFVSTLQRYQEEGVP---VQFDLPDPSPGTTVAVVDQNPSQVRLPAGGGAQ 1030
            +LQ LF    F+   + YQ EG+    + F L D  P   +     NP            
Sbjct: 482  KLQQLFNHTMFILEQEEYQREGIEWNFIDFGL-DLQPCIELIERPNNPP----------- 529

Query: 1031 DARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTEGSSALRTCEQPLQCEIFHQLG 1090
               G+  +LDEE     ++D   +E+LC    ++G+  +     +  +   +  I H  G
Sbjct: 530  ---GVLALLDEECWFPKATDKSFVEKLCT---EQGSHPKFQKP-KQLKDKTEFSIIHYAG 582

Query: 1091 WDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSLFQARAKLPPVCRAVAGLEGTS 1150
               V Y+ + WL +   N+  L+          + + SL  A +      + VA L    
Sbjct: 583  --KVDYNASAWLTK---NMDPLN----------DNVTSLLNASSD-----KFVADLWKDV 622

Query: 1151 QQALQRSRMVRRTFASSLAAVRRKAPCSQI-----KLQMDALTSMIKRSRLHFIHCLVPN 1205
             + +   +M + T +S  +A + K    +      K Q+  L + ++ +  +F+ C++PN
Sbjct: 623  DRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPN 682

Query: 1206 PVVESRSGQESPPPPQPGRDKPGAGGPLALDIPALRVQLAGFHILEALRLHRTGYADHMG 1265
               E RSG+                    LD   +  QL    +LE +R+ R G+ + + 
Sbjct: 683  H--EKRSGK--------------------LDAFLVLEQLRCNGVLEGIRICRQGFPNRIV 720

Query: 1266 LTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLETLDLEKKAVAVGHSQVFLKAGVI 1325
               FR+++++L A  + K       +D ++A   +++ L+L+     +G S++F + GV+
Sbjct: 721  FQEFRQRYEILAANAIPKGF-----MDGKQACILMIKALELDPNLYRIGQSKIFFRTGVL 775

Query: 1326 SRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKNVAVFLAVKDWPWW 1385
            + LE++R+  ++  I+ FQA C+G+L+R+ F K + +  A + IQ+N A +L +++W WW
Sbjct: 776  AHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWW 835

Query: 1386 QLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSD 1445
            +L   ++PLL  T   E+++AKE+E   L++  E+ +K  NEL++    LE K + LT +
Sbjct: 836  RLFTKVKPLLQVTRQEEEMQAKEDE---LQKTKERQQKAENELKE----LEQKHSQLTEE 888

Query: 1446 --LADERFKGDVACQVLESERAERLQAFREV-------------------QELKSKHEQV 1484
              L  E+ + +        E   RL A ++                    Q+L+++ +++
Sbjct: 889  KNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKM 948

Query: 1485 QKKLGDVNKQLEE---AQQKIQLNDLERNPTGGADEWQMRFDCAQM--ENEFLRKRLQQC 1539
             +++ D+ +QLEE   A+QK+QL  +    T  A   ++  +   M  +N  L K  +  
Sbjct: 949  AQQMLDLEEQLEEEEAARQKLQLEKV----TAEAKIKKLEDEILVMDDQNNKLSKERKLL 1004

Query: 1540 EERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRN 1599
            EER+    T   E E+K   L            +LK K   +  +LE   V L+ ++   
Sbjct: 1005 EERISDLTTNLAEEEEKAKNLT-----------KLKNKHESMISELE---VRLKKEEKSR 1050

Query: 1600 HELEKKQKK-------FDLQLAQALGESVFEKGLREKVTQENTSVRWELGQLQQQLKQKE 1652
             ELEK ++K       F  Q+A  L   + E  L+ ++ ++   ++  L +L  ++ QK 
Sbjct: 1051 QELEKLKRKLEGDASDFHEQIAD-LQAQIAE--LKMQLAKKEEELQAALARLDDEIAQKN 1107

Query: 1653 QEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQQKIQSQQENTIK 1712
                ++++    + D  +E L S     N     K  L + E  AL+ + ++   ++T  
Sbjct: 1108 NALKKIRELEGHISD-LQEDLDSERAARNKAEKQKRDLGE-ELEALKTE-LEDTLDSTAT 1164

Query: 1713 QLEQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQLEMQLEQEY------- 1765
            Q ++LR + E E+  +K+   ++    E +++++RQ   + + +L  QLEQ         
Sbjct: 1165 Q-QELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLD 1223

Query: 1766 EEKQMVLHEKQDLEG---LIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTME 1822
            + KQ +  E  DL G   ++G    ++ H+    +K+L   ++   +  SD +     + 
Sbjct: 1224 KNKQTLEKENADLAGELRVLGQAKQEVEHK----KKKLEAQVQELQSKCSDGERARAELN 1279

Query: 1823 DGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQL 1882
            D K    + E+E V   L ++E K  +  K    L++ L+     L+  TR K  V  +L
Sbjct: 1280 D-KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKL 1338

Query: 1883 YRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQ 1942
             +L+ E+  L  ++DE+ +    L +    L  Q +    ++Q+    +E  ++ K + Q
Sbjct: 1339 RQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ 1398

Query: 1943 EQLQVAQMRIE-----YLEQSTVDRAIVSRQEAVICDLENK----TEFQKVQIKRFEVLV 1993
            ++++    + E     Y +       +    + ++ DL+N+    +  +K Q ++F+ L+
Sbjct: 1399 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQ-RKFDQLL 1457

Query: 1994 IRLRDSLIKMGEELSQAATSESQQRESSQYYQRRLEE--------------LKADMEELV 2039
               ++   K  +E  +A     ++   +    R LEE              LKA+ME+LV
Sbjct: 1458 AEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLV 1517

Query: 2040 QREAEASRRCMELEKYVEELAAVRQTLQTDLE 2071
              + +  +   ELEK    L    + ++T LE
Sbjct: 1518 SSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1549



 Score =  147 bits (370), Expect = 2e-34
 Identities = 155/737 (21%), Positives = 335/737 (45%), Gaps = 39/737 (5%)

Query: 1387 LLGSLQPLLSATIGTEQLRAK-EEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSD 1445
            L G L+ L  A    E  + K E ++  L+ K    E+ R EL      L++++  +T  
Sbjct: 1236 LAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGM 1295

Query: 1446 LADERFKGDVACQVLESERAERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQKIQLN 1505
            L +   K       L  + A      ++ QEL  +  + +  +    +QLEE +  +Q  
Sbjct: 1296 LNEAEGKAIK----LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ-- 1349

Query: 1506 DLERNPTGGADEWQMRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYD 1565
            D            +       ++    +K+LQ     +++    +K  ++++  L   Y+
Sbjct: 1350 DQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYE 1409

Query: 1566 GAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKG 1625
                   +L++  + L  +L+D  V L+NQ+     LEKKQ+KFD  LA+    S     
Sbjct: 1410 EKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYAD 1469

Query: 1626 LREKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGS-PSLGENCVA 1684
             R++   E      +   L + L++  +   +L++  +ML+    +L+ S   +G+N V 
Sbjct: 1470 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN-VH 1528

Query: 1685 GLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELE 1744
             L++    LE+   E +    + E+ ++  E  + R E+ ++ +K   ++D + ++E+ E
Sbjct: 1529 ELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNE 1588

Query: 1745 DVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDL 1804
            + R+  Q++LH+ E +LE E +++ +    K+ LEG +  L  Q        E+ +++ L
Sbjct: 1589 EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQ-L 1647

Query: 1805 RRTHALLSDVQLLLGTMEDGKTS-----VSKEELEKVHSQLEQSEAKCEEAL----KTQK 1855
            R+  A + D Q     +ED + S      + +E EK    LE    + +E L    + +K
Sbjct: 1648 RKLQAQMKDFQ---RELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK 1704

Query: 1856 VLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIA 1915
                + E +  EL +    ++ + ++  RL+   A L + ++E+Q ++  +  + +    
Sbjct: 1705 QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ 1764

Query: 1916 QSAADIGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVD--RAIVSRQEAVIC 1973
            Q+     ++   +   ++ +  + +L+ Q +  + ++  +E +     ++ ++  EA I 
Sbjct: 1765 QAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIA 1824

Query: 1974 DLENKTEFQKVQIKRFEVLVIRLRDSLIK-MGEELSQAATSESQQRESSQYYQRRLEELK 2032
             LE + E Q+ + K+     ++ +D  +K +  ++        Q +E ++    R+++LK
Sbjct: 1825 QLEEQVE-QEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLK 1883

Query: 2033 ADMEELVQ--REAEASRRCM--ELEKYVE-------ELAAVRQTLQTDLETSI--RRIAD 2079
              +EE  +  +   A+RR +  EL++  E       E+ A++  L+   ETS    R + 
Sbjct: 1884 RQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSG 1943

Query: 2080 LQAALEEVASSDSDTES 2096
             +  +E    S+ +T++
Sbjct: 1944 GRRVIENADGSEEETDT 1960



 Score =  116 bits (291), Expect = 2e-25
 Identities = 207/1016 (20%), Positives = 414/1016 (40%), Gaps = 136/1016 (13%)

Query: 1293 ERKAVEELLETLDLEKKAVAVGHSQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLS 1352
            ERK +EE +  L           ++   KA  +++L+ + E ++S+  V  +   K   S
Sbjct: 1000 ERKLLEERISDL-------TTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEK---S 1049

Query: 1353 RQEFKKLKIRRLAAQCIQKNVAVFLAVKDWPWWQLLGSLQPLLSATIGTEQLRAKEEELT 1412
            RQE +KLK R+L                   + + +  LQ  ++      QL  KEEEL 
Sbjct: 1050 RQELEKLK-RKLEGDASD-------------FHEQIADLQAQIAEL--KMQLAKKEEELQ 1093

Query: 1413 TLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVA----------CQVLES 1462
                +L+     +N   +    LE  I+DL  DL  ER   + A           + L++
Sbjct: 1094 AALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKT 1153

Query: 1463 ERAERLQAFREVQELKSKHEQ---VQKKLGDVNKQLEEAQQKIQLNDLERNPTGGADEWQ 1519
            E  + L +    QEL++K EQ   V KK  D   +  EAQ + ++            E  
Sbjct: 1154 ELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQ-EMRQKHAQAVEELTEQL 1212

Query: 1520 MRFDCAQMENEFLRKRLQQCEERLDSELTA-----------RKELEQKLGELQSAYDGAK 1568
             +F  A+   +  ++ L++    L  EL             +K+LE ++ ELQS     +
Sbjct: 1213 EQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGE 1272

Query: 1569 KMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLRE 1628
            +   +L  K H L  ++E    +L   + +  +L K       QL     + + ++  R+
Sbjct: 1273 RARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT--QELLQEETRQ 1330

Query: 1629 KVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKE 1688
            K+             +  +L+Q E+E + L+ Q++   + K+ L    S     ++  K+
Sbjct: 1331 KLN------------VSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1378

Query: 1689 RLWKLESS--ALEQQK--IQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELE 1744
            +L    S+  ALE+ K   Q + EN  +Q E+    ++ ++E+ K   Q++ +D   +L+
Sbjct: 1379 KLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYD-KLEKTKNRLQQELDDLVVDLD 1437

Query: 1745 DVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDL 1804
            + RQ     L + + + +Q   E++ +  +  D          +   +   + + L   L
Sbjct: 1438 NQRQLVSN-LEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEAL 1496

Query: 1805 RRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESM 1864
                 L    ++L   MED  +S  K+++ K   +LE+S+   E  ++  K    +LE  
Sbjct: 1497 EAKEELERTNKMLKAEMEDLVSS--KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDE 1554

Query: 1865 HSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQ-------------KHK 1911
                E+  + +  V+ Q  + QFE+ DL  R +++++   +L +             K +
Sbjct: 1555 LQATED-AKLRLEVNMQALKGQFER-DLQARDEQNEEKRRQLQRQLHEYETELEDERKQR 1612

Query: 1912 DLIAQSAADI-GQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQEA 1970
             L A +   + G +++L+LQ + A K + +  +QL+  Q +++  ++   D A  SR E 
Sbjct: 1613 ALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED-ARASRDEI 1671

Query: 1971 VICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQYYQRRLEE 2030
                 EN+ + + ++              L+++ E+L+ A  +  Q     +     L  
Sbjct: 1672 FATAKENEKKAKSLEA------------DLMQLQEDLAAAERARKQADLEKEELAEELAS 1719

Query: 2031 LKADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASS 2090
              +    L   +     R  +LE+ +EE     + +   +  + ++   L   L    S+
Sbjct: 1720 SLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERST 1779

Query: 2091 DSDTESVQTAVDCGSSGRKEMDNVSILSS--QPEGSLQSWLSCTLSLATDTMRTPSRQSA 2148
                ES +  +        E  N  + S   + EG+++S    T+             +A
Sbjct: 1780 AQKNESARQQL--------ERQNKELRSKLHEMEGAVKSKFKSTI-------------AA 1818

Query: 2149 TSSRI--LSPRINEEAGDTERTQSALALSRARSTNVHSKTSGDKPVSPHFVRRQKYCHFG 2206
              ++I  L  ++ +EA + +    +L     +   +  +   ++ ++  +   ++    G
Sbjct: 1819 LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQY---KEQAEKG 1875

Query: 2207 DGEVLAVQRKSTERLEPASSPLASRSTNTSPLSRE--KLPSPSAALSEFVEGLRRK 2260
            +  V  ++R    +LE A       + N   L RE  +    + A+   V  L+ K
Sbjct: 1876 NARVKQLKR----QLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 1927



 Score =  101 bits (252), Expect = 8e-21
 Identities = 134/612 (21%), Positives = 268/612 (43%), Gaps = 66/612 (10%)

Query: 1588 TCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLRE----KVTQENTSVRWELGQ 1643
            T VL   ++ R+ ++      F       L    F K  ++    KV Q N +   +L  
Sbjct: 772  TGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRN 831

Query: 1644 LQQ-QLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWK----LESSAL 1698
             Q  +L  K +   Q+ +Q E +Q  + EL  +    +     LKE   K     E   L
Sbjct: 832  WQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNL 891

Query: 1699 EQQKIQSQQENTIKQLEQLRQRFELEIERMKQ-MHQ-----KDREDQEEELEDVRQSCQK 1752
             Q+++Q++ E    + E++R R   + + +++ +H+     ++ ED+ ++L+  R+   +
Sbjct: 892  LQEQLQAETE-LYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQ 950

Query: 1753 RLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLS 1812
            ++  LE QLE+E   +Q +  EK   E  I  L D+I   D D   +L ++ +     +S
Sbjct: 951  QMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD-DQNNKLSKERKLLEERIS 1009

Query: 1813 DVQLLLGTMEDGKTSVSKEE------LEKVHSQLEQSEAKCEEALKTQKVLTADLESMHS 1866
            D+   L   E+   +++K +      + ++  +L++ E   +E  K ++ L  D    H 
Sbjct: 1010 DLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE 1069

Query: 1867 ELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADIGQIQE 1926
            ++ ++    + +  QL + + E    L R+D++    N  ++K ++L        G I +
Sbjct: 1070 QIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELE-------GHISD 1122

Query: 1927 LQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQI 1986
            LQ  L+  +  ++K ++Q +     +E L+    D             L++    Q+++ 
Sbjct: 1123 LQEDLDSERAARNKAEKQKRDLGEELEALKTELEDT------------LDSTATQQELRA 1170

Query: 1987 KRFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQYYQRRLEELKADMEELVQREAEAS 2046
            KR + + +     L K  +E  +  + E+Q +E  Q + + +EEL   +E+  + +A   
Sbjct: 1171 KREQEVTV-----LKKALDE--ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLD 1223

Query: 2047 RRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSDSDTESVQTAV-DCGS 2105
            +    LEK   +LA   + L    +    +   L+A ++E+ S  SD E  +  + D   
Sbjct: 1224 KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH 1283

Query: 2106 SGRKEMDNVSILSSQPEG----------SLQSWLSCTLSLATDTMR------TPSRQSAT 2149
              + E+++V+ + ++ EG          SL S L  T  L  +  R      T  RQ   
Sbjct: 1284 KLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE 1343

Query: 2150 SSRILSPRINEE 2161
                L  +++EE
Sbjct: 1344 ERNSLQDQLDEE 1355


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score =  422 bits (1085), Expect = e-117
 Identities = 410/1652 (24%), Positives = 764/1652 (46%), Gaps = 222/1652 (13%)

Query: 510  WYEAEKVWL-AQKDGFTLATVL--KPDEGTADLPAGRVRLWIDADKTITEVDEEHVHRAN 566
            W     VW+ ++K GF  A++   K DE   +L        ++  K +T V ++ + + N
Sbjct: 30   WAAKRLVWVPSEKQGFEAASIKEEKGDEVVVEL--------VENGKKVT-VGKDDIQKMN 80

Query: 567  PPELDQVEDLASLISVNESSVLNTLLQRYKAQLLHTCTGPDLIVLQPRGPSVPSAGKVP- 625
            PP+  +VED+A L  +NE+SVL+ L +RY + L++T +G   +V+ P       + K+  
Sbjct: 81   PPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVD 140

Query: 626  --KGR-RDGLPAHIGSMAQRAYWALLNQRRDQSIVALGWSGAGKTTCCEQVLEHLVGMAG 682
              KG+ R  +P HI ++A  AY ++L  R DQSI+  G SGAGKT   ++V+++L  +A 
Sbjct: 141  MYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200

Query: 683  S--------VDGRVSVEKIRATFTVLRAFGSVSMAHSRSATRFSMVMSLDFNATGRITAA 734
            S        + G +  + ++A   +L AFG+     + +++RF   + ++F+ TG I  A
Sbjct: 201  SHKGKKDTSITGELEKQLLQAN-PILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGA 259

Query: 735  QLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTELNLHQMADSSSFGMGVWSKPE 794
             ++T LLEKSR  RQ   E  F +F  M+AG    +R++L L    + +    G    P 
Sbjct: 260  NIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPA 319

Query: 795  DKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAAGACKVGRKQFMRFEWANY 854
             +      F +   AM ++G SE EQ ++ +V++++  LG     K  R         N 
Sbjct: 320  AQDDEM--FQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNI-VFKKERNTDQASMPDNT 376

Query: 855  AAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWGLEDEETSSGLKMTGVDCVEGMASG 914
            AA+ + C    +N   F   +  +  ++  G       D    +  K      VE +A  
Sbjct: 377  AAQKV-CHLMGINVTDFTRSI--LTPRIKVG------RDVVQKAQTKEQADFAVEALAKA 427

Query: 915  LYQELFAAVVSLINRSFSSHHLSMASIM-VVDSPGFQNPRHQGKDRAATFEELCHNYAHE 973
             Y+ LF  +++ +N++    H   AS + ++D  GF+           +FE+LC NY +E
Sbjct: 428  TYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEI------FEVNSFEQLCINYTNE 481

Query: 974  RLQLLFYQRTFVSTLQRYQEEGVP---VQFDLPDPSPGTTVAVVDQNPSQVRLPAGGGAQ 1030
            +LQ LF    F+   + YQ EG+    + F L D  P   +     NP            
Sbjct: 482  KLQQLFNHTMFILEQEEYQREGIEWNFIDFGL-DLQPCIELIERPNNPP----------- 529

Query: 1031 DARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTEGSSALRTCEQPLQCEIFHQLG 1090
               G+  +LDEE     ++D   +E+LC    ++G+  +     +  +   +  I H  G
Sbjct: 530  ---GVLALLDEECWFPKATDKSFVEKLCT---EQGSHPKFQKP-KQLKDKTEFSIIHYAG 582

Query: 1091 WDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSLFQARAKLPPVCRAVAGLEGTS 1150
               V Y+ + WL +   N+  L+          + + SL  A +      + VA L    
Sbjct: 583  --KVDYNASAWLTK---NMDPLN----------DNVTSLLNASSD-----KFVADLWKDV 622

Query: 1151 QQALQRSRMVRRTFASSLAAVRRKAPCSQI-----KLQMDALTSMIKRSRLHFIHCLVPN 1205
             + +   +M + T +S  +A + K    +      K Q+  L + ++ +  +F+ C++PN
Sbjct: 623  DRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPN 682

Query: 1206 PVVESRSGQESPPPPQPGRDKPGAGGPLALDIPALRVQLAGFHILEALRLHRTGYADHMG 1265
               E RSG+                    LD   +  QL    +LE +R+ R G+ + + 
Sbjct: 683  H--EKRSGK--------------------LDAFLVLEQLRCNGVLEGIRICRQGFPNRIV 720

Query: 1266 LTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLETLDLEKKAVAVGHSQVFLKAGVI 1325
               FR+++++L A  + K       +D ++A   +++ L+L+     +G S++F + GV+
Sbjct: 721  FQEFRQRYEILAANAIPKGF-----MDGKQACILMIKALELDPNLYRIGQSKIFFRTGVL 775

Query: 1326 SRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKNVAVFLAVKDWPWW 1385
            + LE++R+  ++  I+ FQA C+G+L+R+ F K + +  A + IQ+N A +L +++W WW
Sbjct: 776  AHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWW 835

Query: 1386 QLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSD 1445
            +L   ++PLL  T   E+++AKE+E   L++  E+ +K  NEL++    LE K + LT +
Sbjct: 836  RLFTKVKPLLQVTRQEEEMQAKEDE---LQKTKERQQKAENELKE----LEQKHSQLTEE 888

Query: 1446 --LADERFKGDVACQVLESERAERLQAFREV-------------------QELKSKHEQV 1484
              L  E+ + +        E   RL A ++                    Q+L+++ +++
Sbjct: 889  KNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKM 948

Query: 1485 QKKLGDVNKQLEE---AQQKIQLNDLERNPTGGADEWQMRFDCAQM--ENEFLRKRLQQC 1539
             +++ D+ +QLEE   A+QK+QL  +    T  A   ++  +   M  +N  L K  +  
Sbjct: 949  AQQMLDLEEQLEEEEAARQKLQLEKV----TAEAKIKKLEDEILVMDDQNNKLSKERKLL 1004

Query: 1540 EERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRN 1599
            EER+    T   E E+K   L            +LK K   +  +LE   V L+ ++   
Sbjct: 1005 EERISDLTTNLAEEEEKAKNLT-----------KLKNKHESMISELE---VRLKKEEKSR 1050

Query: 1600 HELEKKQKK-------FDLQLAQALGESVFEKGLREKVTQENTSVRWELGQLQQQLKQKE 1652
             ELEK ++K       F  Q+A  L   + E  L+ ++ ++   ++  L +L  ++ QK 
Sbjct: 1051 QELEKLKRKLEGDASDFHEQIAD-LQAQIAE--LKMQLAKKEEELQAALARLDDEIAQKN 1107

Query: 1653 QEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQQKIQSQQENTIK 1712
                ++++    + D  +E L S     N     K  L + E  AL+ + ++   ++T  
Sbjct: 1108 NALKKIRELEGHISD-LQEDLDSERAARNKAEKQKRDLGE-ELEALKTE-LEDTLDSTAT 1164

Query: 1713 QLEQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQLEMQLEQEY------- 1765
            Q ++LR + E E+  +K+   ++    E +++++RQ   + + +L  QLEQ         
Sbjct: 1165 Q-QELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLD 1223

Query: 1766 EEKQMVLHEKQDLEG---LIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTME 1822
            + KQ +  E  DL G   ++G    ++ H+    +K+L   ++   +  SD +     + 
Sbjct: 1224 KNKQTLEKENADLAGELRVLGQAKQEVEHK----KKKLEAQVQELQSKCSDGERARAELN 1279

Query: 1823 DGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQL 1882
            D K    + E+E V   L ++E K  +  K    L++ L+     L+  TR K  V  +L
Sbjct: 1280 D-KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKL 1338

Query: 1883 YRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQ 1942
             +L+ E+  L  ++DE+ +    L +    L  Q +    ++Q+    +E  ++ K + Q
Sbjct: 1339 RQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQ 1398

Query: 1943 EQLQVAQMRIE-----YLEQSTVDRAIVSRQEAVICDLENK----TEFQKVQIKRFEVLV 1993
            ++++    + E     Y +       +    + ++ DL+N+    +  +K Q ++F+ L+
Sbjct: 1399 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQ-RKFDQLL 1457

Query: 1994 IRLRDSLIKMGEELSQAATSESQQRESSQYYQRRLEE--------------LKADMEELV 2039
               ++   K  +E  +A     ++   +    R LEE              LKA+ME+LV
Sbjct: 1458 AEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLV 1517

Query: 2040 QREAEASRRCMELEKYVEELAAVRQTLQTDLE 2071
              + +  +   ELEK    L    + ++T LE
Sbjct: 1518 SSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1549



 Score =  145 bits (365), Expect = 7e-34
 Identities = 141/686 (20%), Positives = 311/686 (45%), Gaps = 26/686 (3%)

Query: 1387 LLGSLQPLLSATIGTEQLRAK-EEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSD 1445
            L G L+ L  A    E  + K E ++  L+ K    E+ R EL      L++++  +T  
Sbjct: 1236 LAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGM 1295

Query: 1446 LADERFKGDVACQVLESERAERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQKIQLN 1505
            L +   K       L  + A      ++ QEL  +  + +  +    +QLEE +  +Q  
Sbjct: 1296 LNEAEGKAIK----LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ-- 1349

Query: 1506 DLERNPTGGADEWQMRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYD 1565
            D            +       ++    +K+LQ     +++    +K  ++++  L   Y+
Sbjct: 1350 DQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYE 1409

Query: 1566 GAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKG 1625
                   +L++  + L  +L+D  V L+NQ+     LEKKQ+KFD  LA+    S     
Sbjct: 1410 EKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYAD 1469

Query: 1626 LREKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGS-PSLGENCVA 1684
             R++   E      +   L + L++  +   +L++  +ML+    +L+ S   +G+N V 
Sbjct: 1470 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN-VH 1528

Query: 1685 GLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELE 1744
             L++    LE+   E +    + E+ ++  E  + R E+ ++ +K   ++D + ++E+ E
Sbjct: 1529 ELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNE 1588

Query: 1745 DVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDL 1804
            + R+  Q++LH+ E +LE E +++ +    K+ LEG +  L  Q        E+ +++ L
Sbjct: 1589 EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQ-L 1647

Query: 1805 RRTHALLSDVQLLLGTMEDGKTS-----VSKEELEKVHSQLEQSEAKCEEAL----KTQK 1855
            R+  A + D Q     +ED + S      + +E EK    LE    + +E L    + +K
Sbjct: 1648 RKLQAQMKDFQ---RELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK 1704

Query: 1856 VLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIA 1915
                + E +  EL +    ++ + ++  RL+   A L + ++E+Q ++  +  + +    
Sbjct: 1705 QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ 1764

Query: 1916 QSAADIGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVD--RAIVSRQEAVIC 1973
            Q+     ++   +   ++ +  + +L+ Q +  + ++  +E +     ++ ++  EA I 
Sbjct: 1765 QAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIA 1824

Query: 1974 DLENKTEFQKVQIKRFEVLVIRLRDSLIK-MGEELSQAATSESQQRESSQYYQRRLEELK 2032
             LE + E Q+ + K+     ++ +D  +K +  ++        Q +E ++    R+++LK
Sbjct: 1825 QLEEQVE-QEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLK 1883

Query: 2033 ADMEELVQREAEASRRCMELEKYVEE 2058
              +EE  +     +    +L++ ++E
Sbjct: 1884 RQLEEAEEESQRINANRRKLQRELDE 1909



 Score =  132 bits (332), Expect = 4e-30
 Identities = 186/829 (22%), Positives = 350/829 (42%), Gaps = 116/829 (13%)

Query: 1293 ERKAVEELLETLDLEKKAVAVGHSQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLS 1352
            ERK +EE +  L           ++   KA  +++L+ + E ++S+  V  +   K   S
Sbjct: 1000 ERKLLEERISDL-------TTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEK---S 1049

Query: 1353 RQEFKKLKIRRLAAQCIQKNVAVFLAVKDWPWWQLLGSLQPLLSATIGTEQLRAKEEELT 1412
            RQE +KLK R+L                   + + +  LQ  ++      QL  KEEEL 
Sbjct: 1050 RQELEKLK-RKLEGDASD-------------FHEQIADLQAQIAEL--KMQLAKKEEELQ 1093

Query: 1413 TLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVA----------CQVLES 1462
                +L+     +N   +    LE  I+DL  DL  ER   + A           + L++
Sbjct: 1094 AALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKT 1153

Query: 1463 ERAERLQAFREVQELKSKHEQ---VQKKLGDVNKQLEEAQQKIQLNDLERNPTGGADEWQ 1519
            E  + L +    QEL++K EQ   V KK  D   +  EAQ +                 +
Sbjct: 1154 ELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQ-----------------E 1196

Query: 1520 MRFDCAQMENEFLRK--RLQQCEERLD-SELTARKELEQKLGELQSAYDGAKKMAHQLKR 1576
            MR   AQ   E   +  + ++ +  LD ++ T  KE     GEL+      +++ H+ K+
Sbjct: 1197 MRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK-KK 1255

Query: 1577 KCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTS 1636
            K      +L+  C    + +    EL  K  K   ++    G     +G   K+ ++  S
Sbjct: 1256 KLEAQVQELQSKC---SDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVAS 1312

Query: 1637 VRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESS 1696
            +  +L   Q+ L+++ ++   +  ++  L++ +  L             L+  +  L   
Sbjct: 1313 LSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQ 1372

Query: 1697 ALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQ 1756
              + +K      +T++ LE+ ++RF+ EIE + Q ++ ++    ++LE  +   Q+ L  
Sbjct: 1373 LSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYE-EKAAAYDKLEKTKNRLQQELDD 1431

Query: 1757 LEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQL 1816
            L + L+ +   +Q+V                            L +  R+   LL++ + 
Sbjct: 1432 LVVDLDNQ---RQLV--------------------------SNLEKKQRKFDQLLAEEKN 1462

Query: 1817 LLGTMEDGKTSVSKEELEKVHSQL-------EQSEAKCEEALKTQKVLTADLESMHSELE 1869
            +     D +     E  EK    L       E  EAK EE  +T K+L A++E + S  +
Sbjct: 1463 ISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSSKD 1521

Query: 1870 NMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADIGQIQ-ELQ 1928
            ++ +N   +++    L+ +  ++  +++E +D+L         L     A  GQ + +LQ
Sbjct: 1522 DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1581

Query: 1929 LQLEEAKKEKHKLQEQLQVAQMRIE-YLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIK 1987
             + E+ ++++ +LQ QL   +  +E   +Q  +  A   + E  + DLE + +     IK
Sbjct: 1582 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSA---IK 1638

Query: 1988 RFEVLVIRLRDSLIKMGE---ELSQAATSESQQRESSQYYQRRLEELKADM----EELVQ 2040
              E  + +LR    +M +   EL  A  S  +   +++  +++ + L+AD+    E+L  
Sbjct: 1639 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1698

Query: 2041 REAEASRRCMELEKYVEELAAV---RQTLQTDLETSIRRIADLQAALEE 2086
             E    +  +E E+  EELA+    R  LQ +      RIA L+  LEE
Sbjct: 1699 AERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE 1747



 Score =  101 bits (252), Expect = 8e-21
 Identities = 134/612 (21%), Positives = 268/612 (43%), Gaps = 66/612 (10%)

Query: 1588 TCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLRE----KVTQENTSVRWELGQ 1643
            T VL   ++ R+ ++      F       L    F K  ++    KV Q N +   +L  
Sbjct: 772  TGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRN 831

Query: 1644 LQQ-QLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWK----LESSAL 1698
             Q  +L  K +   Q+ +Q E +Q  + EL  +    +     LKE   K     E   L
Sbjct: 832  WQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNL 891

Query: 1699 EQQKIQSQQENTIKQLEQLRQRFELEIERMKQ-MHQ-----KDREDQEEELEDVRQSCQK 1752
             Q+++Q++ E    + E++R R   + + +++ +H+     ++ ED+ ++L+  R+   +
Sbjct: 892  LQEQLQAETE-LYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQ 950

Query: 1753 RLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLS 1812
            ++  LE QLE+E   +Q +  EK   E  I  L D+I   D D   +L ++ +     +S
Sbjct: 951  QMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD-DQNNKLSKERKLLEERIS 1009

Query: 1813 DVQLLLGTMEDGKTSVSKEE------LEKVHSQLEQSEAKCEEALKTQKVLTADLESMHS 1866
            D+   L   E+   +++K +      + ++  +L++ E   +E  K ++ L  D    H 
Sbjct: 1010 DLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE 1069

Query: 1867 ELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADIGQIQE 1926
            ++ ++    + +  QL + + E    L R+D++    N  ++K ++L        G I +
Sbjct: 1070 QIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELE-------GHISD 1122

Query: 1927 LQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQI 1986
            LQ  L+  +  ++K ++Q +     +E L+    D             L++    Q+++ 
Sbjct: 1123 LQEDLDSERAARNKAEKQKRDLGEELEALKTELEDT------------LDSTATQQELRA 1170

Query: 1987 KRFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQYYQRRLEELKADMEELVQREAEAS 2046
            KR + + +     L K  +E  +  + E+Q +E  Q + + +EEL   +E+  + +A   
Sbjct: 1171 KREQEVTV-----LKKALDE--ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLD 1223

Query: 2047 RRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSDSDTESVQTAV-DCGS 2105
            +    LEK   +LA   + L    +    +   L+A ++E+ S  SD E  +  + D   
Sbjct: 1224 KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH 1283

Query: 2106 SGRKEMDNVSILSSQPEG----------SLQSWLSCTLSLATDTMR------TPSRQSAT 2149
              + E+++V+ + ++ EG          SL S L  T  L  +  R      T  RQ   
Sbjct: 1284 KLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE 1343

Query: 2150 SSRILSPRINEE 2161
                L  +++EE
Sbjct: 1344 ERNSLQDQLDEE 1355



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 134/622 (21%), Positives = 272/622 (43%), Gaps = 92/622 (14%)

Query: 1281 LKKLMSTSEGIDE-RKAVEELLETLDLEKKAVAVGHSQVFLKAGVISRLEKQREKLVSQ- 1338
            L+   ST E ++E +K  ++ +E L  + +           KA    +LEK + +L  + 
Sbjct: 1380 LQDFASTVEALEEGKKRFQKEIENLTQQYEE----------KAAAYDKLEKTKNRLQQEL 1429

Query: 1339 -SIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKNVAVFLAVKDWPWWQLLGSLQPLLSA 1397
              +V+     +  +S  E K+ K  +L A+  +KN++   A +                 
Sbjct: 1430 DDLVVDLDNQRQLVSNLEKKQRKFDQLLAE--EKNISSKYADE----------------R 1471

Query: 1398 TIGTEQLRAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVAC 1457
                 + R KE +  +L R LE++ + + EL +   +L++++ DL S       K DV  
Sbjct: 1472 DRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSS------KDDVGK 1525

Query: 1458 QVLESERAERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPTGGADE 1517
             V E E+++R     +++E+K++ E+++ +L    +  E+A+ ++++N            
Sbjct: 1526 NVHELEKSKRALE-TQMEEMKTQLEELEDEL----QATEDAKLRLEVN------------ 1568

Query: 1518 WQMRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRK 1577
              M+    Q E + L+ R +Q EE+       R++L+++L E ++  +  +K        
Sbjct: 1569 --MQALKGQFERD-LQARDEQNEEK-------RRQLQRQLHEYETELEDERKQRALAAAA 1618

Query: 1578 CHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKV---TQEN 1634
               L  DL+D  +  ++      E  K+ +K   Q+     E    +  R+++    +EN
Sbjct: 1619 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1678

Query: 1635 TSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLE 1694
                  L     QL++    A + ++Q ++ ++   E L S   G N +   K RL    
Sbjct: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRL---- 1734

Query: 1695 SSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRL 1754
                 + +I   +E    +LE+ +   E   +R+++  Q+  E    EL   R + QK  
Sbjct: 1735 -----EARIAQLEE----ELEEEQGNMEAMSDRVRKATQQ-AEQLSNELATERSTAQKN- 1783

Query: 1755 HQLEMQLEQEYEEKQMVLHE-----KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHA 1809
                 QLE++ +E +  LHE     K   +  I  L  +I   +  VE+  R     T +
Sbjct: 1784 ESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS 1843

Query: 1810 LLSD----VQLLLGTMEDGKTSVS-KEELEKVHSQLEQSEAKCEEALKTQKVLTADLESM 1864
            L        ++LL   ++ K +   KE+ EK +++++Q + + EEA +  + + A+   +
Sbjct: 1844 LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKL 1903

Query: 1865 HSELENMTRNKSLVDEQLYRLQ 1886
              EL+  T +   +  ++  L+
Sbjct: 1904 QRELDEATESNEAMGREVNALK 1925


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score =  419 bits (1077), Expect = e-116
 Identities = 409/1658 (24%), Positives = 762/1658 (45%), Gaps = 227/1658 (13%)

Query: 510  WYEAEKVWL-AQKDGFTLATVL--KPDEGTADLPAGRVRLWIDADKTITEVDEEHVHRAN 566
            W     VW+ ++K GF  A++   K DE   +L        ++  K +T V ++ + + N
Sbjct: 30   WAAKRLVWVPSEKQGFEAASIKEEKGDEVVVEL--------VENGKKVT-VGKDDIQKMN 80

Query: 567  PPELDQVEDLASLISVNESSVLNTLLQRYKAQLLHTCTGPDLIVLQPRGPSVPSAGKVP- 625
            PP+  +VED+A L  +NE+SVL+ L +RY + L++T +G   +V+ P       + K+  
Sbjct: 81   PPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVD 140

Query: 626  --KGR-RDGLPAHIGSMAQRAYWALLNQRRDQSIVALGWSGAGKTTCCEQVLEHLVGMAG 682
              KG+ R  +P HI ++A  AY ++L  R DQSI+  G SGAGKT   ++V+++L  +A 
Sbjct: 141  MYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200

Query: 683  SVDGRVSV--------------EKIRATFTVLRAFGSVSMAHSRSATRFSMVMSLDFNAT 728
            S  G+                 +++     +L AFG+     + +++RF   + ++F+ T
Sbjct: 201  SHKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVT 260

Query: 729  GRITAAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTELNLHQMADSSSFGMG 788
            G I  A ++T LLEKSR  RQ   E  F +F  M+AG    +R++L L    + +    G
Sbjct: 261  GYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNG 320

Query: 789  VWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAAGACKVGRKQFMR 848
                P  +      F +   AM ++G SE EQ ++ +V++++  LG     K  R     
Sbjct: 321  FVPIPAAQDDEM--FQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNI-VFKKERNTDQA 377

Query: 849  FEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWGLEDEETSSGLKMTGVDCV 908
                N AA+ + C    +N   F   +  +  ++  G       D    +  K      V
Sbjct: 378  SMPDNTAAQKV-CHLMGINVTDFTRSI--LTPRIKVG------RDVVQKAQTKEQADFAV 428

Query: 909  EGMASGLYQELFAAVVSLINRSFSSHHLSMASIM-VVDSPGFQNPRHQGKDRAATFEELC 967
            E +A   Y+ LF  +++ +N++    H   AS + ++D  GF+           +FE+LC
Sbjct: 429  EALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEI------FEVNSFEQLC 482

Query: 968  HNYAHERLQLLFYQRTFVSTLQRYQEEGVP---VQFDLPDPSPGTTVAVVDQNPSQVRLP 1024
             NY +E+LQ LF    F+   + YQ EG+    + F L D  P   +     NP      
Sbjct: 483  INYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGL-DLQPCIELIERPNNPP----- 536

Query: 1025 AGGGAQDARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTEGSSALRTCEQPLQCE 1084
                     G+  +LDEE     ++D   +E+LC    ++G+  +     +  +   +  
Sbjct: 537  ---------GVLALLDEECWFPKATDKSFVEKLCT---EQGSHPKFQKP-KQLKDKTEFS 583

Query: 1085 IFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSLFQARAKLPPVCRAVA 1144
            I H  G   V Y+ + WL +   N+  L+          + + SL  A +      + VA
Sbjct: 584  IIHYAG--KVDYNASAWLTK---NMDPLN----------DNVTSLLNASSD-----KFVA 623

Query: 1145 GLEGTSQQALQRSRMVRRTFASSLAAVRRKAPCSQI-----KLQMDALTSMIKRSRLHFI 1199
             L     + +   +M + T +S  +A + K    +      K Q+  L + ++ +  +F+
Sbjct: 624  DLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFV 683

Query: 1200 HCLVPNPVVESRSGQESPPPPQPGRDKPGAGGPLALDIPALRVQLAGFHILEALRLHRTG 1259
             C++PN   E RSG+                    LD   +  QL    +LE +R+ R G
Sbjct: 684  RCIIPNH--EKRSGK--------------------LDAFLVLEQLRCNGVLEGIRICRQG 721

Query: 1260 YADHMGLTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLETLDLEKKAVAVGHSQVF 1319
            + + +    FR+++++L A  + K       +D ++A   +++ L+L+     +G S++F
Sbjct: 722  FPNRIVFQEFRQRYEILAANAIPKGF-----MDGKQACILMIKALELDPNLYRIGQSKIF 776

Query: 1320 LKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKNVAVFLAV 1379
             + GV++ LE++R+  ++  I+ FQA C+G+L+R+ F K + +  A + IQ+N A +L +
Sbjct: 777  FRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKL 836

Query: 1380 KDWPWWQLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKI 1439
            ++W WW+L   ++PLL  T   E+++AKE+E   L++  E+ +K  NEL++    LE K 
Sbjct: 837  RNWQWWRLFTKVKPLLQVTRQEEEMQAKEDE---LQKTKERQQKAENELKE----LEQKH 889

Query: 1440 ADLTSD--LADERFKGDVACQVLESERAERLQAFREV-------------------QELK 1478
            + LT +  L  E+ + +        E   RL A ++                    Q+L+
Sbjct: 890  SQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ 949

Query: 1479 SKHEQVQKKLGDVNKQLEE---AQQKIQLNDLERNPTGGADEWQMRFDCAQM--ENEFLR 1533
            ++ +++ +++ D+ +QLEE   A+QK+QL  +    T  A   ++  +   M  +N  L 
Sbjct: 950  AERKKMAQQMLDLEEQLEEEEAARQKLQLEKV----TAEAKIKKLEDEILVMDDQNNKLS 1005

Query: 1534 KRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLE 1593
            K  +  EER+    T   E E+K   L            +LK K   +  +LE   V L+
Sbjct: 1006 KERKLLEERISDLTTNLAEEEEKAKNLT-----------KLKNKHESMISELE---VRLK 1051

Query: 1594 NQQSRNHELEKKQKK-------FDLQLAQALGESVFEKGLREKVTQENTSVRWELGQLQQ 1646
             ++    ELEK ++K       F  Q+A  L   + E  L+ ++ ++   ++  L +L  
Sbjct: 1052 KEEKSRQELEKLKRKLEGDASDFHEQIAD-LQAQIAE--LKMQLAKKEEELQAALARLDD 1108

Query: 1647 QLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQQKIQSQ 1706
            ++ QK     ++++    + D  +E L S     N     K  L + E  AL+ + ++  
Sbjct: 1109 EIAQKNNALKKIRELEGHISD-LQEDLDSERAARNKAEKQKRDLGE-ELEALKTE-LEDT 1165

Query: 1707 QENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQLEMQLEQEY- 1765
             ++T  Q ++LR + E E+  +K+   ++    E +++++RQ   + + +L  QLEQ   
Sbjct: 1166 LDSTATQ-QELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKR 1224

Query: 1766 ------EEKQMVLHEKQDLEG---LIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQL 1816
                  + KQ +  E  DL G   ++G    ++ H+    +K+L   ++   +  SD + 
Sbjct: 1225 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK----KKKLEAQVQELQSKCSDGER 1280

Query: 1817 LLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKS 1876
                + D K    + E+E V   L ++E K  +  K    L++ L+     L+  TR K 
Sbjct: 1281 ARAELND-KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKL 1339

Query: 1877 LVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKK 1936
             V  +L +L+ E+  L  ++DE+ +    L +    L  Q +    ++Q+    +E  ++
Sbjct: 1340 NVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE 1399

Query: 1937 EKHKLQEQLQVAQMRIE-----YLEQSTVDRAIVSRQEAVICDLENK----TEFQKVQIK 1987
             K + Q++++    + E     Y +       +    + ++ DL+N+    +  +K Q +
Sbjct: 1400 GKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQ-R 1458

Query: 1988 RFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQYYQRRLEE--------------LKA 2033
            +F+ L+   ++   K  +E  +A     ++   +    R LEE              LKA
Sbjct: 1459 KFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKA 1518

Query: 2034 DMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLE 2071
            +ME+LV  + +  +   ELEK    L    + ++T LE
Sbjct: 1519 EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1556



 Score =  147 bits (370), Expect = 2e-34
 Identities = 155/737 (21%), Positives = 335/737 (45%), Gaps = 39/737 (5%)

Query: 1387 LLGSLQPLLSATIGTEQLRAK-EEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSD 1445
            L G L+ L  A    E  + K E ++  L+ K    E+ R EL      L++++  +T  
Sbjct: 1243 LAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGM 1302

Query: 1446 LADERFKGDVACQVLESERAERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQKIQLN 1505
            L +   K       L  + A      ++ QEL  +  + +  +    +QLEE +  +Q  
Sbjct: 1303 LNEAEGKAIK----LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ-- 1356

Query: 1506 DLERNPTGGADEWQMRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYD 1565
            D            +       ++    +K+LQ     +++    +K  ++++  L   Y+
Sbjct: 1357 DQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYE 1416

Query: 1566 GAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKG 1625
                   +L++  + L  +L+D  V L+NQ+     LEKKQ+KFD  LA+    S     
Sbjct: 1417 EKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYAD 1476

Query: 1626 LREKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGS-PSLGENCVA 1684
             R++   E      +   L + L++  +   +L++  +ML+    +L+ S   +G+N V 
Sbjct: 1477 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN-VH 1535

Query: 1685 GLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELE 1744
             L++    LE+   E +    + E+ ++  E  + R E+ ++ +K   ++D + ++E+ E
Sbjct: 1536 ELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNE 1595

Query: 1745 DVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDL 1804
            + R+  Q++LH+ E +LE E +++ +    K+ LEG +  L  Q        E+ +++ L
Sbjct: 1596 EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQ-L 1654

Query: 1805 RRTHALLSDVQLLLGTMEDGKTS-----VSKEELEKVHSQLEQSEAKCEEAL----KTQK 1855
            R+  A + D Q     +ED + S      + +E EK    LE    + +E L    + +K
Sbjct: 1655 RKLQAQMKDFQ---RELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK 1711

Query: 1856 VLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIA 1915
                + E +  EL +    ++ + ++  RL+   A L + ++E+Q ++  +  + +    
Sbjct: 1712 QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ 1771

Query: 1916 QSAADIGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVD--RAIVSRQEAVIC 1973
            Q+     ++   +   ++ +  + +L+ Q +  + ++  +E +     ++ ++  EA I 
Sbjct: 1772 QAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIA 1831

Query: 1974 DLENKTEFQKVQIKRFEVLVIRLRDSLIK-MGEELSQAATSESQQRESSQYYQRRLEELK 2032
             LE + E Q+ + K+     ++ +D  +K +  ++        Q +E ++    R+++LK
Sbjct: 1832 QLEEQVE-QEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLK 1890

Query: 2033 ADMEELVQ--REAEASRRCM--ELEKYVE-------ELAAVRQTLQTDLETSI--RRIAD 2079
              +EE  +  +   A+RR +  EL++  E       E+ A++  L+   ETS    R + 
Sbjct: 1891 RQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSFVPSRRSG 1950

Query: 2080 LQAALEEVASSDSDTES 2096
             +  +E    S+ +T++
Sbjct: 1951 GRRVIENADGSEEETDT 1967



 Score =  116 bits (291), Expect = 2e-25
 Identities = 207/1016 (20%), Positives = 414/1016 (40%), Gaps = 136/1016 (13%)

Query: 1293 ERKAVEELLETLDLEKKAVAVGHSQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLS 1352
            ERK +EE +  L           ++   KA  +++L+ + E ++S+  V  +   K   S
Sbjct: 1007 ERKLLEERISDL-------TTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEK---S 1056

Query: 1353 RQEFKKLKIRRLAAQCIQKNVAVFLAVKDWPWWQLLGSLQPLLSATIGTEQLRAKEEELT 1412
            RQE +KLK R+L                   + + +  LQ  ++      QL  KEEEL 
Sbjct: 1057 RQELEKLK-RKLEGDASD-------------FHEQIADLQAQIAEL--KMQLAKKEEELQ 1100

Query: 1413 TLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVA----------CQVLES 1462
                +L+     +N   +    LE  I+DL  DL  ER   + A           + L++
Sbjct: 1101 AALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKT 1160

Query: 1463 ERAERLQAFREVQELKSKHEQ---VQKKLGDVNKQLEEAQQKIQLNDLERNPTGGADEWQ 1519
            E  + L +    QEL++K EQ   V KK  D   +  EAQ + ++            E  
Sbjct: 1161 ELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQ-EMRQKHAQAVEELTEQL 1219

Query: 1520 MRFDCAQMENEFLRKRLQQCEERLDSELTA-----------RKELEQKLGELQSAYDGAK 1568
             +F  A+   +  ++ L++    L  EL             +K+LE ++ ELQS     +
Sbjct: 1220 EQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGE 1279

Query: 1569 KMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLRE 1628
            +   +L  K H L  ++E    +L   + +  +L K       QL     + + ++  R+
Sbjct: 1280 RARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDT--QELLQEETRQ 1337

Query: 1629 KVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKE 1688
            K+             +  +L+Q E+E + L+ Q++   + K+ L    S     ++  K+
Sbjct: 1338 KLN------------VSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1385

Query: 1689 RLWKLESS--ALEQQK--IQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELE 1744
            +L    S+  ALE+ K   Q + EN  +Q E+    ++ ++E+ K   Q++ +D   +L+
Sbjct: 1386 KLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYD-KLEKTKNRLQQELDDLVVDLD 1444

Query: 1745 DVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDL 1804
            + RQ     L + + + +Q   E++ +  +  D          +   +   + + L   L
Sbjct: 1445 NQRQLVSN-LEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEAL 1503

Query: 1805 RRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESM 1864
                 L    ++L   MED  +S  K+++ K   +LE+S+   E  ++  K    +LE  
Sbjct: 1504 EAKEELERTNKMLKAEMEDLVSS--KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDE 1561

Query: 1865 HSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQ-------------KHK 1911
                E+  + +  V+ Q  + QFE+ DL  R +++++   +L +             K +
Sbjct: 1562 LQATED-AKLRLEVNMQALKGQFER-DLQARDEQNEEKRRQLQRQLHEYETELEDERKQR 1619

Query: 1912 DLIAQSAADI-GQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQEA 1970
             L A +   + G +++L+LQ + A K + +  +QL+  Q +++  ++   D A  SR E 
Sbjct: 1620 ALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED-ARASRDEI 1678

Query: 1971 VICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQYYQRRLEE 2030
                 EN+ + + ++              L+++ E+L+ A  +  Q     +     L  
Sbjct: 1679 FATAKENEKKAKSLEA------------DLMQLQEDLAAAERARKQADLEKEELAEELAS 1726

Query: 2031 LKADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASS 2090
              +    L   +     R  +LE+ +EE     + +   +  + ++   L   L    S+
Sbjct: 1727 SLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERST 1786

Query: 2091 DSDTESVQTAVDCGSSGRKEMDNVSILSS--QPEGSLQSWLSCTLSLATDTMRTPSRQSA 2148
                ES +  +        E  N  + S   + EG+++S    T+             +A
Sbjct: 1787 AQKNESARQQL--------ERQNKELRSKLHEMEGAVKSKFKSTI-------------AA 1825

Query: 2149 TSSRI--LSPRINEEAGDTERTQSALALSRARSTNVHSKTSGDKPVSPHFVRRQKYCHFG 2206
              ++I  L  ++ +EA + +    +L     +   +  +   ++ ++  +   ++    G
Sbjct: 1826 LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQY---KEQAEKG 1882

Query: 2207 DGEVLAVQRKSTERLEPASSPLASRSTNTSPLSRE--KLPSPSAALSEFVEGLRRK 2260
            +  V  ++R    +LE A       + N   L RE  +    + A+   V  L+ K
Sbjct: 1883 NARVKQLKR----QLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSK 1934



 Score =  101 bits (252), Expect = 8e-21
 Identities = 134/612 (21%), Positives = 268/612 (43%), Gaps = 66/612 (10%)

Query: 1588 TCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLRE----KVTQENTSVRWELGQ 1643
            T VL   ++ R+ ++      F       L    F K  ++    KV Q N +   +L  
Sbjct: 779  TGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRN 838

Query: 1644 LQQ-QLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWK----LESSAL 1698
             Q  +L  K +   Q+ +Q E +Q  + EL  +    +     LKE   K     E   L
Sbjct: 839  WQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNL 898

Query: 1699 EQQKIQSQQENTIKQLEQLRQRFELEIERMKQ-MHQ-----KDREDQEEELEDVRQSCQK 1752
             Q+++Q++ E    + E++R R   + + +++ +H+     ++ ED+ ++L+  R+   +
Sbjct: 899  LQEQLQAETE-LYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQ 957

Query: 1753 RLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLS 1812
            ++  LE QLE+E   +Q +  EK   E  I  L D+I   D D   +L ++ +     +S
Sbjct: 958  QMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD-DQNNKLSKERKLLEERIS 1016

Query: 1813 DVQLLLGTMEDGKTSVSKEE------LEKVHSQLEQSEAKCEEALKTQKVLTADLESMHS 1866
            D+   L   E+   +++K +      + ++  +L++ E   +E  K ++ L  D    H 
Sbjct: 1017 DLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE 1076

Query: 1867 ELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADIGQIQE 1926
            ++ ++    + +  QL + + E    L R+D++    N  ++K ++L        G I +
Sbjct: 1077 QIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELE-------GHISD 1129

Query: 1927 LQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQI 1986
            LQ  L+  +  ++K ++Q +     +E L+    D             L++    Q+++ 
Sbjct: 1130 LQEDLDSERAARNKAEKQKRDLGEELEALKTELEDT------------LDSTATQQELRA 1177

Query: 1987 KRFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQYYQRRLEELKADMEELVQREAEAS 2046
            KR + + +     L K  +E  +  + E+Q +E  Q + + +EEL   +E+  + +A   
Sbjct: 1178 KREQEVTV-----LKKALDE--ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLD 1230

Query: 2047 RRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSDSDTESVQTAV-DCGS 2105
            +    LEK   +LA   + L    +    +   L+A ++E+ S  SD E  +  + D   
Sbjct: 1231 KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH 1290

Query: 2106 SGRKEMDNVSILSSQPEG----------SLQSWLSCTLSLATDTMR------TPSRQSAT 2149
              + E+++V+ + ++ EG          SL S L  T  L  +  R      T  RQ   
Sbjct: 1291 KLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE 1350

Query: 2150 SSRILSPRINEE 2161
                L  +++EE
Sbjct: 1351 ERNSLQDQLDEE 1362


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score =  419 bits (1077), Expect = e-116
 Identities = 409/1658 (24%), Positives = 762/1658 (45%), Gaps = 227/1658 (13%)

Query: 510  WYEAEKVWL-AQKDGFTLATVL--KPDEGTADLPAGRVRLWIDADKTITEVDEEHVHRAN 566
            W     VW+ ++K GF  A++   K DE   +L        ++  K +T V ++ + + N
Sbjct: 30   WAAKRLVWVPSEKQGFEAASIKEEKGDEVVVEL--------VENGKKVT-VGKDDIQKMN 80

Query: 567  PPELDQVEDLASLISVNESSVLNTLLQRYKAQLLHTCTGPDLIVLQPRGPSVPSAGKVP- 625
            PP+  +VED+A L  +NE+SVL+ L +RY + L++T +G   +V+ P       + K+  
Sbjct: 81   PPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVD 140

Query: 626  --KGR-RDGLPAHIGSMAQRAYWALLNQRRDQSIVALGWSGAGKTTCCEQVLEHLVGMAG 682
              KG+ R  +P HI ++A  AY ++L  R DQSI+  G SGAGKT   ++V+++L  +A 
Sbjct: 141  MYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200

Query: 683  SVDGRVSV--------------EKIRATFTVLRAFGSVSMAHSRSATRFSMVMSLDFNAT 728
            S  G+                 +++     +L AFG+     + +++RF   + ++F+ T
Sbjct: 201  SHKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVT 260

Query: 729  GRITAAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTELNLHQMADSSSFGMG 788
            G I  A ++T LLEKSR  RQ   E  F +F  M+AG    +R++L L    + +    G
Sbjct: 261  GYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNG 320

Query: 789  VWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAAGACKVGRKQFMR 848
                P  +      F +   AM ++G SE EQ ++ +V++++  LG     K  R     
Sbjct: 321  FVPIPAAQDDEM--FQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNI-VFKKERNTDQA 377

Query: 849  FEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWGLEDEETSSGLKMTGVDCV 908
                N AA+ + C    +N   F   +  +  ++  G       D    +  K      V
Sbjct: 378  SMPDNTAAQKV-CHLMGINVTDFTRSI--LTPRIKVG------RDVVQKAQTKEQADFAV 428

Query: 909  EGMASGLYQELFAAVVSLINRSFSSHHLSMASIM-VVDSPGFQNPRHQGKDRAATFEELC 967
            E +A   Y+ LF  +++ +N++    H   AS + ++D  GF+           +FE+LC
Sbjct: 429  EALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEI------FEVNSFEQLC 482

Query: 968  HNYAHERLQLLFYQRTFVSTLQRYQEEGVP---VQFDLPDPSPGTTVAVVDQNPSQVRLP 1024
             NY +E+LQ LF    F+   + YQ EG+    + F L D  P   +     NP      
Sbjct: 483  INYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGL-DLQPCIELIERPNNPP----- 536

Query: 1025 AGGGAQDARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTEGSSALRTCEQPLQCE 1084
                     G+  +LDEE     ++D   +E+LC    ++G+  +     +  +   +  
Sbjct: 537  ---------GVLALLDEECWFPKATDKSFVEKLCT---EQGSHPKFQKP-KQLKDKTEFS 583

Query: 1085 IFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSLFQARAKLPPVCRAVA 1144
            I H  G   V Y+ + WL +   N+  L+          + + SL  A +      + VA
Sbjct: 584  IIHYAG--KVDYNASAWLTK---NMDPLN----------DNVTSLLNASSD-----KFVA 623

Query: 1145 GLEGTSQQALQRSRMVRRTFASSLAAVRRKAPCSQI-----KLQMDALTSMIKRSRLHFI 1199
             L     + +   +M + T +S  +A + K    +      K Q+  L + ++ +  +F+
Sbjct: 624  DLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFV 683

Query: 1200 HCLVPNPVVESRSGQESPPPPQPGRDKPGAGGPLALDIPALRVQLAGFHILEALRLHRTG 1259
             C++PN   E RSG+                    LD   +  QL    +LE +R+ R G
Sbjct: 684  RCIIPNH--EKRSGK--------------------LDAFLVLEQLRCNGVLEGIRICRQG 721

Query: 1260 YADHMGLTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLETLDLEKKAVAVGHSQVF 1319
            + + +    FR+++++L A  + K       +D ++A   +++ L+L+     +G S++F
Sbjct: 722  FPNRIVFQEFRQRYEILAANAIPKGF-----MDGKQACILMIKALELDPNLYRIGQSKIF 776

Query: 1320 LKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKNVAVFLAV 1379
             + GV++ LE++R+  ++  I+ FQA C+G+L+R+ F K + +  A + IQ+N A +L +
Sbjct: 777  FRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKL 836

Query: 1380 KDWPWWQLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKI 1439
            ++W WW+L   ++PLL  T   E+++AKE+E   L++  E+ +K  NEL++    LE K 
Sbjct: 837  RNWQWWRLFTKVKPLLQVTRQEEEMQAKEDE---LQKTKERQQKAENELKE----LEQKH 889

Query: 1440 ADLTSD--LADERFKGDVACQVLESERAERLQAFREV-------------------QELK 1478
            + LT +  L  E+ + +        E   RL A ++                    Q+L+
Sbjct: 890  SQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQ 949

Query: 1479 SKHEQVQKKLGDVNKQLEE---AQQKIQLNDLERNPTGGADEWQMRFDCAQM--ENEFLR 1533
            ++ +++ +++ D+ +QLEE   A+QK+QL  +    T  A   ++  +   M  +N  L 
Sbjct: 950  AERKKMAQQMLDLEEQLEEEEAARQKLQLEKV----TAEAKIKKLEDEILVMDDQNNKLS 1005

Query: 1534 KRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLE 1593
            K  +  EER+    T   E E+K   L            +LK K   +  +LE   V L+
Sbjct: 1006 KERKLLEERISDLTTNLAEEEEKAKNLT-----------KLKNKHESMISELE---VRLK 1051

Query: 1594 NQQSRNHELEKKQKK-------FDLQLAQALGESVFEKGLREKVTQENTSVRWELGQLQQ 1646
             ++    ELEK ++K       F  Q+A  L   + E  L+ ++ ++   ++  L +L  
Sbjct: 1052 KEEKSRQELEKLKRKLEGDASDFHEQIAD-LQAQIAE--LKMQLAKKEEELQAALARLDD 1108

Query: 1647 QLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQQKIQSQ 1706
            ++ QK     ++++    + D  +E L S     N     K  L + E  AL+ + ++  
Sbjct: 1109 EIAQKNNALKKIRELEGHISD-LQEDLDSERAARNKAEKQKRDLGE-ELEALKTE-LEDT 1165

Query: 1707 QENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQLEMQLEQEY- 1765
             ++T  Q ++LR + E E+  +K+   ++    E +++++RQ   + + +L  QLEQ   
Sbjct: 1166 LDSTATQ-QELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKR 1224

Query: 1766 ------EEKQMVLHEKQDLEG---LIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQL 1816
                  + KQ +  E  DL G   ++G    ++ H+    +K+L   ++   +  SD + 
Sbjct: 1225 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK----KKKLEAQVQELQSKCSDGER 1280

Query: 1817 LLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKS 1876
                + D K    + E+E V   L ++E K  +  K    L++ L+     L+  TR K 
Sbjct: 1281 ARAELND-KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKL 1339

Query: 1877 LVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKK 1936
             V  +L +L+ E+  L  ++DE+ +    L +    L  Q +    ++Q+    +E  ++
Sbjct: 1340 NVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE 1399

Query: 1937 EKHKLQEQLQVAQMRIE-----YLEQSTVDRAIVSRQEAVICDLENK----TEFQKVQIK 1987
             K + Q++++    + E     Y +       +    + ++ DL+N+    +  +K Q +
Sbjct: 1400 GKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQ-R 1458

Query: 1988 RFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQYYQRRLEE--------------LKA 2033
            +F+ L+   ++   K  +E  +A     ++   +    R LEE              LKA
Sbjct: 1459 KFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKA 1518

Query: 2034 DMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLE 2071
            +ME+LV  + +  +   ELEK    L    + ++T LE
Sbjct: 1519 EMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1556



 Score =  145 bits (365), Expect = 7e-34
 Identities = 141/686 (20%), Positives = 311/686 (45%), Gaps = 26/686 (3%)

Query: 1387 LLGSLQPLLSATIGTEQLRAK-EEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSD 1445
            L G L+ L  A    E  + K E ++  L+ K    E+ R EL      L++++  +T  
Sbjct: 1243 LAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGM 1302

Query: 1446 LADERFKGDVACQVLESERAERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQKIQLN 1505
            L +   K       L  + A      ++ QEL  +  + +  +    +QLEE +  +Q  
Sbjct: 1303 LNEAEGKAIK----LAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQ-- 1356

Query: 1506 DLERNPTGGADEWQMRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYD 1565
            D            +       ++    +K+LQ     +++    +K  ++++  L   Y+
Sbjct: 1357 DQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYE 1416

Query: 1566 GAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKG 1625
                   +L++  + L  +L+D  V L+NQ+     LEKKQ+KFD  LA+    S     
Sbjct: 1417 EKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYAD 1476

Query: 1626 LREKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGS-PSLGENCVA 1684
             R++   E      +   L + L++  +   +L++  +ML+    +L+ S   +G+N V 
Sbjct: 1477 ERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN-VH 1535

Query: 1685 GLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELE 1744
             L++    LE+   E +    + E+ ++  E  + R E+ ++ +K   ++D + ++E+ E
Sbjct: 1536 ELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNE 1595

Query: 1745 DVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDL 1804
            + R+  Q++LH+ E +LE E +++ +    K+ LEG +  L  Q        E+ +++ L
Sbjct: 1596 EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQ-L 1654

Query: 1805 RRTHALLSDVQLLLGTMEDGKTS-----VSKEELEKVHSQLEQSEAKCEEAL----KTQK 1855
            R+  A + D Q     +ED + S      + +E EK    LE    + +E L    + +K
Sbjct: 1655 RKLQAQMKDFQ---RELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK 1711

Query: 1856 VLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIA 1915
                + E +  EL +    ++ + ++  RL+   A L + ++E+Q ++  +  + +    
Sbjct: 1712 QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ 1771

Query: 1916 QSAADIGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVD--RAIVSRQEAVIC 1973
            Q+     ++   +   ++ +  + +L+ Q +  + ++  +E +     ++ ++  EA I 
Sbjct: 1772 QAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIA 1831

Query: 1974 DLENKTEFQKVQIKRFEVLVIRLRDSLIK-MGEELSQAATSESQQRESSQYYQRRLEELK 2032
             LE + E Q+ + K+     ++ +D  +K +  ++        Q +E ++    R+++LK
Sbjct: 1832 QLEEQVE-QEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLK 1890

Query: 2033 ADMEELVQREAEASRRCMELEKYVEE 2058
              +EE  +     +    +L++ ++E
Sbjct: 1891 RQLEEAEEESQRINANRRKLQRELDE 1916



 Score =  132 bits (332), Expect = 4e-30
 Identities = 186/829 (22%), Positives = 350/829 (42%), Gaps = 116/829 (13%)

Query: 1293 ERKAVEELLETLDLEKKAVAVGHSQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLS 1352
            ERK +EE +  L           ++   KA  +++L+ + E ++S+  V  +   K   S
Sbjct: 1007 ERKLLEERISDL-------TTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEK---S 1056

Query: 1353 RQEFKKLKIRRLAAQCIQKNVAVFLAVKDWPWWQLLGSLQPLLSATIGTEQLRAKEEELT 1412
            RQE +KLK R+L                   + + +  LQ  ++      QL  KEEEL 
Sbjct: 1057 RQELEKLK-RKLEGDASD-------------FHEQIADLQAQIAEL--KMQLAKKEEELQ 1100

Query: 1413 TLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVA----------CQVLES 1462
                +L+     +N   +    LE  I+DL  DL  ER   + A           + L++
Sbjct: 1101 AALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKT 1160

Query: 1463 ERAERLQAFREVQELKSKHEQ---VQKKLGDVNKQLEEAQQKIQLNDLERNPTGGADEWQ 1519
            E  + L +    QEL++K EQ   V KK  D   +  EAQ +                 +
Sbjct: 1161 ELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQ-----------------E 1203

Query: 1520 MRFDCAQMENEFLRK--RLQQCEERLD-SELTARKELEQKLGELQSAYDGAKKMAHQLKR 1576
            MR   AQ   E   +  + ++ +  LD ++ T  KE     GEL+      +++ H+ K+
Sbjct: 1204 MRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK-KK 1262

Query: 1577 KCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTS 1636
            K      +L+  C    + +    EL  K  K   ++    G     +G   K+ ++  S
Sbjct: 1263 KLEAQVQELQSKC---SDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVAS 1319

Query: 1637 VRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESS 1696
            +  +L   Q+ L+++ ++   +  ++  L++ +  L             L+  +  L   
Sbjct: 1320 LSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQ 1379

Query: 1697 ALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQ 1756
              + +K      +T++ LE+ ++RF+ EIE + Q ++ ++    ++LE  +   Q+ L  
Sbjct: 1380 LSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYE-EKAAAYDKLEKTKNRLQQELDD 1438

Query: 1757 LEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQL 1816
            L + L+ +   +Q+V                            L +  R+   LL++ + 
Sbjct: 1439 LVVDLDNQ---RQLV--------------------------SNLEKKQRKFDQLLAEEKN 1469

Query: 1817 LLGTMEDGKTSVSKEELEKVHSQL-------EQSEAKCEEALKTQKVLTADLESMHSELE 1869
            +     D +     E  EK    L       E  EAK EE  +T K+L A++E + S  +
Sbjct: 1470 ISSKYADERDRAEAEAREKETKALSLARALEEALEAK-EELERTNKMLKAEMEDLVSSKD 1528

Query: 1870 NMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADIGQIQ-ELQ 1928
            ++ +N   +++    L+ +  ++  +++E +D+L         L     A  GQ + +LQ
Sbjct: 1529 DVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1588

Query: 1929 LQLEEAKKEKHKLQEQLQVAQMRIE-YLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIK 1987
             + E+ ++++ +LQ QL   +  +E   +Q  +  A   + E  + DLE + +     IK
Sbjct: 1589 ARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSA---IK 1645

Query: 1988 RFEVLVIRLRDSLIKMGE---ELSQAATSESQQRESSQYYQRRLEELKADM----EELVQ 2040
              E  + +LR    +M +   EL  A  S  +   +++  +++ + L+AD+    E+L  
Sbjct: 1646 GREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 1705

Query: 2041 REAEASRRCMELEKYVEELAAV---RQTLQTDLETSIRRIADLQAALEE 2086
             E    +  +E E+  EELA+    R  LQ +      RIA L+  LEE
Sbjct: 1706 AERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE 1754



 Score =  101 bits (252), Expect = 8e-21
 Identities = 134/612 (21%), Positives = 268/612 (43%), Gaps = 66/612 (10%)

Query: 1588 TCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLRE----KVTQENTSVRWELGQ 1643
            T VL   ++ R+ ++      F       L    F K  ++    KV Q N +   +L  
Sbjct: 779  TGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRN 838

Query: 1644 LQQ-QLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWK----LESSAL 1698
             Q  +L  K +   Q+ +Q E +Q  + EL  +    +     LKE   K     E   L
Sbjct: 839  WQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNL 898

Query: 1699 EQQKIQSQQENTIKQLEQLRQRFELEIERMKQ-MHQ-----KDREDQEEELEDVRQSCQK 1752
             Q+++Q++ E    + E++R R   + + +++ +H+     ++ ED+ ++L+  R+   +
Sbjct: 899  LQEQLQAETE-LYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQ 957

Query: 1753 RLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLS 1812
            ++  LE QLE+E   +Q +  EK   E  I  L D+I   D D   +L ++ +     +S
Sbjct: 958  QMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMD-DQNNKLSKERKLLEERIS 1016

Query: 1813 DVQLLLGTMEDGKTSVSKEE------LEKVHSQLEQSEAKCEEALKTQKVLTADLESMHS 1866
            D+   L   E+   +++K +      + ++  +L++ E   +E  K ++ L  D    H 
Sbjct: 1017 DLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE 1076

Query: 1867 ELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADIGQIQE 1926
            ++ ++    + +  QL + + E    L R+D++    N  ++K ++L        G I +
Sbjct: 1077 QIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELE-------GHISD 1129

Query: 1927 LQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQI 1986
            LQ  L+  +  ++K ++Q +     +E L+    D             L++    Q+++ 
Sbjct: 1130 LQEDLDSERAARNKAEKQKRDLGEELEALKTELEDT------------LDSTATQQELRA 1177

Query: 1987 KRFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQYYQRRLEELKADMEELVQREAEAS 2046
            KR + + +     L K  +E  +  + E+Q +E  Q + + +EEL   +E+  + +A   
Sbjct: 1178 KREQEVTV-----LKKALDE--ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLD 1230

Query: 2047 RRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSDSDTESVQTAV-DCGS 2105
            +    LEK   +LA   + L    +    +   L+A ++E+ S  SD E  +  + D   
Sbjct: 1231 KNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH 1290

Query: 2106 SGRKEMDNVSILSSQPEG----------SLQSWLSCTLSLATDTMR------TPSRQSAT 2149
              + E+++V+ + ++ EG          SL S L  T  L  +  R      T  RQ   
Sbjct: 1291 KLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE 1350

Query: 2150 SSRILSPRINEE 2161
                L  +++EE
Sbjct: 1351 ERNSLQDQLDEE 1362



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 134/622 (21%), Positives = 272/622 (43%), Gaps = 92/622 (14%)

Query: 1281 LKKLMSTSEGIDE-RKAVEELLETLDLEKKAVAVGHSQVFLKAGVISRLEKQREKLVSQ- 1338
            L+   ST E ++E +K  ++ +E L  + +           KA    +LEK + +L  + 
Sbjct: 1387 LQDFASTVEALEEGKKRFQKEIENLTQQYEE----------KAAAYDKLEKTKNRLQQEL 1436

Query: 1339 -SIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKNVAVFLAVKDWPWWQLLGSLQPLLSA 1397
              +V+     +  +S  E K+ K  +L A+  +KN++   A +                 
Sbjct: 1437 DDLVVDLDNQRQLVSNLEKKQRKFDQLLAE--EKNISSKYADE----------------R 1478

Query: 1398 TIGTEQLRAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVAC 1457
                 + R KE +  +L R LE++ + + EL +   +L++++ DL S       K DV  
Sbjct: 1479 DRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSS------KDDVGK 1532

Query: 1458 QVLESERAERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPTGGADE 1517
             V E E+++R     +++E+K++ E+++ +L    +  E+A+ ++++N            
Sbjct: 1533 NVHELEKSKRALE-TQMEEMKTQLEELEDEL----QATEDAKLRLEVN------------ 1575

Query: 1518 WQMRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRK 1577
              M+    Q E + L+ R +Q EE+       R++L+++L E ++  +  +K        
Sbjct: 1576 --MQALKGQFERD-LQARDEQNEEK-------RRQLQRQLHEYETELEDERKQRALAAAA 1625

Query: 1578 CHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKV---TQEN 1634
               L  DL+D  +  ++      E  K+ +K   Q+     E    +  R+++    +EN
Sbjct: 1626 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1685

Query: 1635 TSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLE 1694
                  L     QL++    A + ++Q ++ ++   E L S   G N +   K RL    
Sbjct: 1686 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRL---- 1741

Query: 1695 SSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRL 1754
                 + +I   +E    +LE+ +   E   +R+++  Q+  E    EL   R + QK  
Sbjct: 1742 -----EARIAQLEE----ELEEEQGNMEAMSDRVRKATQQ-AEQLSNELATERSTAQKN- 1790

Query: 1755 HQLEMQLEQEYEEKQMVLHE-----KQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHA 1809
                 QLE++ +E +  LHE     K   +  I  L  +I   +  VE+  R     T +
Sbjct: 1791 ESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKS 1850

Query: 1810 LLSD----VQLLLGTMEDGKTSVS-KEELEKVHSQLEQSEAKCEEALKTQKVLTADLESM 1864
            L        ++LL   ++ K +   KE+ EK +++++Q + + EEA +  + + A+   +
Sbjct: 1851 LKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKL 1910

Query: 1865 HSELENMTRNKSLVDEQLYRLQ 1886
              EL+  T +   +  ++  L+
Sbjct: 1911 QRELDEATESNEAMGREVNALK 1932


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score =  412 bits (1058), Expect = e-114
 Identities = 420/1775 (23%), Positives = 792/1775 (44%), Gaps = 266/1775 (14%)

Query: 505  APEDRWYEAEKVWL-AQKDGFTLATVLKPDEGTADLPAGRVRLWIDADKTITEVDEEHVH 563
            A +  W   + VW+ +++ GF  A++ K + G   +    V L  +  K +  V+++ + 
Sbjct: 25   ATQADWTAKKLVWIPSERHGFEAASI-KEERGDEVM----VELAENGKKAM--VNKDDIQ 77

Query: 564  RANPPELDQVEDLASLISVNESSVLNTLLQRYKAQLLHTCTGPDLIVLQP-RGPSVPSAG 622
            + NPP+  +VED+A L  +NE+SVL+ L  RY + L++T +G   +V+ P +   + S  
Sbjct: 78   KMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSEN 137

Query: 623  KVPKGR---RDGLPAHIGSMAQRAYWALLNQRRDQSIVALGWSGAGKTTCCEQVLEHLVG 679
             +   R   R  +P HI ++++ AY  +L  R DQSI+  G SGAGKT   ++V+++L  
Sbjct: 138  IIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAH 197

Query: 680  MAGSVDGRVS-------VEKIRATFTVLRAFGSVSMAHSRSATRFSMVMSLDFNATGRIT 732
            +A S  GR           ++     +L +FG+     + +++RF   + ++F+ TG I 
Sbjct: 198  VASSHKGRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIV 257

Query: 733  AAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTELNLHQMADSSSFGMGVWSK 792
             A ++T LLEKSR  RQ + E  F +F Q+L+G    L+++L L    +      G    
Sbjct: 258  GANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFLSNGYIPI 317

Query: 793  PEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAAGACKVGRKQFMRFEWA 852
            P  + K    F +   AM ++G S  E  ++ +V++++   G   + K  R         
Sbjct: 318  PGQQDKDN--FQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNI-SFKKERNTDQASMPE 374

Query: 853  NYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWGLEDEETSSGLKMTGVDCVEGMA 912
            N  A+ L C    +N   F   +  +  ++  G       D    +  K      VE +A
Sbjct: 375  NTVAQKL-CHLLGMNVMEFTRAI--LTPRIKVG------RDYVQKAQTKEQADFAVEALA 425

Query: 913  SGLYQELFAAVVSLINRSFSSHHLSMASIM-VVDSPGFQNPRHQGKDRAATFEELCHNYA 971
               Y+ LF  +V  IN++        AS + ++D  GF+           +FE+LC NY 
Sbjct: 426  KATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEI------FELNSFEQLCINYT 479

Query: 972  HERLQLLFYQRTFVSTLQRYQEEGVP---VQFDLPDPSPGTTVAVVDQNPSQVRLPAGGG 1028
            +E+LQ LF    F+   + YQ EG+    + F L D  P   +     NP          
Sbjct: 480  NEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGL-DLQPCIDLIERPANPP--------- 529

Query: 1029 AQDARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTEGSSALRTCEQPLQCEIFHQ 1088
                 G+  +LDEE     ++D   +E+L    +++G+ ++     +  ++   C I H 
Sbjct: 530  -----GVLALLDEECWFPKATDKTFVEKLV---QEQGSHSKFQKPRQLKDKADFC-IIHY 580

Query: 1089 LGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSLFQARAKLPPVCRAVAGLEG 1148
             G   V Y    WL +    L+  +   +LHQS    +  L++   ++  + +     E 
Sbjct: 581  AG--KVDYKADEWLMKNMDPLND-NVATLLHQSSDRFVAELWKDVDRIVGLDQVTGMTET 637

Query: 1149 TSQQALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMDALTSMIKRSRLHFIHCLVPNPVV 1208
                A +  + + RT                 K  +  L + ++ +  +F+ C++PN   
Sbjct: 638  AFGSAYKTKKGMFRTVGQLY------------KESLTKLMATLRNTNPNFVRCIIPNH-- 683

Query: 1209 ESRSGQESPPPPQPGRDKPGAGGPLALDIPALRVQLAGFHILEALRLHRTGYADHMGLTR 1268
            E R+G+  P               L LD      QL    +LE +R+ R G+ + +    
Sbjct: 684  EKRAGKLDPH--------------LVLD------QLRCNGVLEGIRICRQGFPNRIVFQE 723

Query: 1269 FRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLETLDLEKKAVAVGHSQVFLKAGVISRL 1328
            FR+++++L    + K       +D ++A E ++  L+L+     +G S++F +AGV++ L
Sbjct: 724  FRQRYEILTPNAIPKGF-----MDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHL 778

Query: 1329 EKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKNVAVFLAVKDWPWWQLL 1388
            E++R+  ++  I+ FQA C+G+L+R+ F K + +  A + +Q+N A +L ++ W WW++ 
Sbjct: 779  EEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVF 838

Query: 1389 GSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSE-KLRNELRQNTDLLESKIADLTSDLA 1447
              ++PLL  T   E+L+AK+EEL  ++ K  K E +L    R++  LLE K      ++ 
Sbjct: 839  TKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEK------NIL 892

Query: 1448 DERFKGDVACQVLESERAERLQAFR-EVQELKSKHEQVQKKLGDVNKQLEEAQQKIQ--L 1504
             E+ + +        E   RL A + E++E+    E   ++  + N+ L+  ++K+Q  +
Sbjct: 893  AEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHI 952

Query: 1505 NDLER---NPTGGADEWQMRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQ 1561
             DLE       G   + Q+    A+ + + + + +   E++    +  +K +E ++ E  
Sbjct: 953  QDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECS 1012

Query: 1562 SAY----DGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQAL 1617
            S      + AK +A +++ K   +  DLE+    L+ ++    ELEK ++K D       
Sbjct: 1013 SQLAEEEEKAKNLA-KIRNKQEVMISDLEER---LKKEEKTRQELEKAKRKLD------- 1061

Query: 1618 GESVFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPS 1677
            GE+     L++++ +    ++ ++ +L+ QL +KE+E      + +    HK   L    
Sbjct: 1062 GETT---DLQDQIAE----LQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVR 1114

Query: 1678 LGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLE-----------------QLRQR 1720
              +  +A L+E     ES    + K + Q+ +  ++LE                 +LR +
Sbjct: 1115 ELQAQIAELQE---DFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTK 1171

Query: 1721 FELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLE- 1779
             E E+  +K+  +++ ++ E +++D+RQ     L +L  QLEQ    K  +   KQ LE 
Sbjct: 1172 REQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLET 1231

Query: 1780 -----GLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSKEELE 1834
                      +  Q+        K+L   ++  HA +S+   L   + + K S  + EL+
Sbjct: 1232 DNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAE-KASKLQNELD 1290

Query: 1835 KVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNK------------------- 1875
             V + LE++E K  +  K    L + L+     L+  TR K                   
Sbjct: 1291 NVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQE 1350

Query: 1876 ---------SLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADIGQIQE 1926
                       +++Q+  LQ + AD  K++D+D   +  L +  K L+  + A   +++E
Sbjct: 1351 QQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE 1410

Query: 1927 LQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQI 1986
              L  ++ +K K++LQ++          L+  TVD   +  Q  V  +LE K        
Sbjct: 1411 KALAYDKLEKTKNRLQQE----------LDDLTVD---LDHQRQVASNLEKKQ------- 1450

Query: 1987 KRFEVLVIRLRDSLIKMGEELSQA--------------ATSESQQRESSQYYQRRLEELK 2032
            K+F+ L+   +    +  EE  +A              A +  +  E+ + ++R+ ++L+
Sbjct: 1451 KKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLR 1510

Query: 2033 ADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSDS 2092
            ADME+L+  + +  +   ELEK    L               +++ +++  LEE+     
Sbjct: 1511 ADMEDLMSSKDDVGKNVHELEKSKRALE--------------QQVEEMRTQLEELEDELQ 1556

Query: 2093 DTESVQTAVDCGSSGRKEMDNVSILSSQPEGSLQSWLSCTLSLATDTMRTPSRQSATSSR 2152
             TE  +  ++          N+  + +Q E  LQ               T   Q+    R
Sbjct: 1557 ATEDAKLRLEV---------NMQAMKAQFERDLQ---------------TRDEQNEEKKR 1592

Query: 2153 ILSPRINEEAG--DTERTQSALALSRARSTNVHSK 2185
            +L  ++ E     + ER Q ALA++  +   +  K
Sbjct: 1593 LLIKQVRELEAELEDERKQRALAVASKKKMEIDLK 1627



 Score =  150 bits (380), Expect = 1e-35
 Identities = 156/731 (21%), Positives = 334/731 (45%), Gaps = 54/731 (7%)

Query: 1402 EQLRAKEEELTTLRRKL-EKSEKLRNELRQNTDLLES---KIADLTSDLADERFKGDVAC 1457
            ++L AK  E   LR +L EK+ KL+NEL   + LLE    K      D A    +     
Sbjct: 1262 QELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQ 1321

Query: 1458 QVLESERAERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPTGGADE 1517
            ++L+ E  ++L     +++L+ +   +Q++     ++ EEA++ ++   L         +
Sbjct: 1322 ELLQEETRQKLNLSSRIRQLEEEKNSLQEQ----QEEEEEARKNLEKQVLALQSQLADTK 1377

Query: 1518 WQMRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRK 1577
             ++  D   +E+      L++ +++L  +  A   L Q+L E   AYD  +K  ++L+++
Sbjct: 1378 KKVDDDLGTIES------LEEAKKKLLKDAEA---LSQRLEEKALAYDKLEKTKNRLQQE 1428

Query: 1578 CHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSV 1637
               LT DL+       +Q+     LEKKQKKFD  LA+    S      R++   E    
Sbjct: 1429 LDDLTVDLD-------HQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREK 1481

Query: 1638 RWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPS-LGENCVAGLKERLWKLESS 1696
              +   L + L++  +   + ++Q + L+    +L+ S   +G+N V  L++    LE  
Sbjct: 1482 ETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKN-VHELEKSKRALEQQ 1540

Query: 1697 ALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQ 1756
              E +    + E+ ++  E  + R E+ ++ MK   ++D + ++E+ E+ ++   K++ +
Sbjct: 1541 VEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRE 1600

Query: 1757 LEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQL 1816
            LE +LE E +++ + +  K+ +E  +  L  QI   +      + + LR+  A + D Q 
Sbjct: 1601 LEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAAN-KARDEVIKQLRKLQAQMKDYQR 1659

Query: 1817 LLGTMEDGKTSV------SKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELEN 1870
             L      +  +      S+++L+ + +++ Q + +   + + ++    + + +  E+ N
Sbjct: 1660 ELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITN 1719

Query: 1871 MTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQ 1930
                KS + ++  RL+   A L + ++E+Q ++  L  + +    Q      ++   +  
Sbjct: 1720 SASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSA 1779

Query: 1931 LEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDR--AIVSRQEAVICDLENKTEFQKVQIKR 1988
             +++   + +L+ Q +  + +++ LE +   +  A +S  EA I  LE + E +  +   
Sbjct: 1780 AQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAA 1839

Query: 1989 FEVLVIRLRDSLIKMGEELSQAATSESQQRESSQYYQRRLEELKADMEELVQREAEASRR 2048
               LV R    L ++  ++        Q +E  +    R+++LK  +EE  +    A+  
Sbjct: 1840 ANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANAS 1899

Query: 2049 CMELEKYVEELAAVRQTLQTDLET-----------------SIRRIADLQAALEEVASSD 2091
              +L++ +++     + L  ++ T                 S RR   L+ A  E+  SD
Sbjct: 1900 RRKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFSSSRSGRRQLHLEGASLEL--SD 1957

Query: 2092 SDTESVQTAVD 2102
             DTES  + V+
Sbjct: 1958 DDTESKTSDVN 1968



 Score =  124 bits (312), Expect = 9e-28
 Identities = 185/806 (22%), Positives = 379/806 (47%), Gaps = 84/806 (10%)

Query: 1391 LQPLLSATIGTEQLRAK-EEELTTLRRKLEKSEKLRNELRQNTDLLE---SKIADLTSDL 1446
            L+  L  T   ++LR K E+E+  L++ LE  E+ +N   Q  D+ +   + + +L+  L
Sbjct: 1155 LEDTLDTTAAQQELRTKREQEVAELKKALE--EETKNHEAQIQDMRQRHATALEELSEQL 1212

Query: 1447 AD-ERFKGDVAC--QVLESERAERLQAFREVQELKSKHEQVQKKL-------------GD 1490
               +RFK ++    Q LE++  E     + +Q++K++ E  +KKL             GD
Sbjct: 1213 EQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGD 1272

Query: 1491 -VNKQLEEAQQKIQLNDLERNPT--GGADEWQMRF--DCAQMENEFL-RKRLQQCEERLD 1544
             +  +L E   K+Q N+L+   T    A++  ++F  D A +E++    + L Q E R  
Sbjct: 1273 RLRVELAEKASKLQ-NELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQK 1331

Query: 1545 SELTAR-KELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELE 1603
              L++R ++LE++   LQ   +  ++    L+++   L   L DT   +++       LE
Sbjct: 1332 LNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLE 1391

Query: 1604 KKQKKFDLQLAQALGESVFEKGLR-EKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQV 1662
            + +KK  L+ A+AL + + EK L  +K+ +    ++ EL  L   L  + Q AS L+++ 
Sbjct: 1392 EAKKKL-LKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQ 1450

Query: 1663 EMLQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQRFE 1722
            +       +LL      ++  A   E   + E+ A E++   ++  +  + LE+  +  E
Sbjct: 1451 KKFD----QLLAEE---KSISARYAEERDRAEAEAREKE---TKALSLARALEEALEAKE 1500

Query: 1723 LEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQLEMQ---LEQEYEEKQMVLHEKQDLE 1779
             E ER  +  + D ED     +DV     K +H+LE     LEQ+ EE +  L E +D  
Sbjct: 1501 -EFERQNKQLRADMEDLMSSKDDVG----KNVHELEKSKRALEQQVEEMRTQLEELED-- 1553

Query: 1780 GLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLS-DVQLLLGTMEDGKTSVSKEELEKVHS 1838
                    ++   + D + RL  +++   A    D+Q      E+ K  + K+ + ++ +
Sbjct: 1554 --------ELQATE-DAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQ-VRELEA 1603

Query: 1839 QLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDE 1898
            +LE    +   A+ ++K +  DL+ + +++E   + +  V +QL +LQ +  D  + ++E
Sbjct: 1604 ELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEE 1663

Query: 1899 DQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQS 1958
             +   +E+  + K+  ++      + + LQLQ E A  E+ +   + +  ++  E    +
Sbjct: 1664 ARASRDEIFAQSKE--SEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSA 1721

Query: 1959 TVDRAIVS---RQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIK---MGEELSQAAT 2012
            +   A++    R EA I  LE + E ++      E+L  R R + ++   +  EL+   +
Sbjct: 1722 SGKSALLDEKRRLEARIAQLEEELEEEQ---SNMELLNDRFRKTTLQVDTLNAELAAERS 1778

Query: 2013 SESQQRESSQYYQRRLEELKADMEEL---VQREAEASRRCME-----LEKYVEELAAVRQ 2064
            +  +   + Q  +R+ +ELKA ++EL   V+ + +A+   +E     LE+ +E+ A  R 
Sbjct: 1779 AAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERA 1838

Query: 2065 TLQTDLETSIRRIADLQAALE-EVASSDSDTESVQTAVDCGSSGRKEMDNVSILSSQPEG 2123
                 +  + +++ ++   +E E   +D   E ++ A       +++++     +++   
Sbjct: 1839 AANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANA 1898

Query: 2124 SLQSWLSCTLSLATDTMRTPSRQSAT 2149
            S +  L   L  AT+     SR+ +T
Sbjct: 1899 SRRK-LQRELDDATEANEGLSREVST 1923


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score =  400 bits (1027), Expect = e-110
 Identities = 419/1699 (24%), Positives = 788/1699 (46%), Gaps = 232/1699 (13%)

Query: 510  WYEAEKVWL-AQKDGFTLATVLKPDEGTADLPAGRVRLWIDADKTITEVDEEHVHRANPP 568
            W   + VW+ + K GF  A+ LK + G   +    V L  +  K   +V+++ + + NPP
Sbjct: 26   WAAKKLVWVPSDKSGFEPAS-LKEEVGEEAI----VELVENGKKV--KVNKDDIQKMNPP 78

Query: 569  ELDQVEDLASLISVNESSVLNTLLQRYKAQLLHTCTGPDLIVLQPRGPSVPSAGK----V 624
            +  +VED+A L  +NE+SVL+ L +RY + L++T +G   +V+ P   ++P   +    +
Sbjct: 79   KFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPY-KNLPIYSEEIVEM 137

Query: 625  PKGR-RDGLPAHIGSMAQRAYWALLNQRRDQSIVALGWSGAGKTTCCEQVLEHLVGMAGS 683
             KG+ R  +P HI ++   AY +++  R DQSI+  G SGAGKT   ++V+++L  +A S
Sbjct: 138  YKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASS 197

Query: 684  V-----DGRVSVEKIRATFTVLRAFGSVSMAHSRSATRFSMVMSLDFNATGRITAAQLQT 738
                   G +  + ++A   +L AFG+     + +++RF   + ++F+  G I  A ++T
Sbjct: 198  HKSKKDQGELERQLLQAN-PILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIET 256

Query: 739  MLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTELNLHQMADSSSFGMGVWSKPEDKQK 798
             LLEKSR  RQ + E  F +F  +L+G    L+T+L L           G  + P  + K
Sbjct: 257  YLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIPGQQDK 316

Query: 799  AAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAAGACKVGRKQFMRFEWANYAAEA 858
                F +   AM ++GI E EQ  + RV++ +  LG     K  R         N AA+ 
Sbjct: 317  DM--FQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNI-VFKKERNTDQASMPDNTAAQK 373

Query: 859  LGCEYEELNTATFKHHLRQIIQQMTFGPSRWGLEDEETSSGLKMTGVDCVEGMASGLYQE 918
            +      +N   F   +  +  ++  G       D    +  K      +E +A   Y+ 
Sbjct: 374  VS-HLLGINVTDFTRGI--LTPRIKVG------RDYVQKAQTKEQADFAIEALAKATYER 424

Query: 919  LFAAVVSLINRSFSSHHLSMASIM-VVDSPGFQNPRHQGKDRAATFEELCHNYAHERLQL 977
            +F  +V  IN++        AS + ++D  GF+           +FE+LC NY +E+LQ 
Sbjct: 425  MFRWLVLRINKALDKTKRQGASFIGILDIAGFEI------FDLNSFEQLCINYTNEKLQQ 478

Query: 978  LFYQRTFVSTLQRYQEEGVP---VQFDLPDPSPGTTVAVVDQNPSQVRLPAGGGAQDARG 1034
            LF    F+   + YQ EG+    + F L D  P   +         +  PAG       G
Sbjct: 479  LFNHTMFILEQEEYQREGIEWNFIDFGL-DLQPCIDL---------IEKPAG-----PPG 523

Query: 1035 LFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTEGSSALRTCEQPLQCEIFHQLGWDPV 1094
            +  +LDEE     ++D   +E++    +++G   +     +  ++   C I H  G   V
Sbjct: 524  ILALLDEECWFPKATDKSFVEKV---MQEQGTHPKFQKPKQLKDKADFC-IIHYAG--KV 577

Query: 1095 RYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSLFQARAKLPPVCRAVAGLE---GTSQ 1151
             Y    WL +    L+  +   +LHQS  + +  L++   +       + GL+   G S+
Sbjct: 578  DYKADEWLMKNMDPLND-NIATLLHQSSDKFVSELWKDVDR-------IIGLDQVAGMSE 629

Query: 1152 QALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMDALTSMIKRSRLHFIHCLVPNPVVESR 1211
             AL  +   R+    ++  + ++        Q+  L + ++ +  +F+ C++PN   E +
Sbjct: 630  TALPGAFKTRKGMFRTVGQLYKE--------QLAKLMATLRNTNPNFVRCIIPNH--EKK 679

Query: 1212 SGQESPPPPQPGRDKPGAGGPLALDIPALRVQLAGFHILEALRLHRTGYADHMGLTRFRR 1271
            +G+  P               L LD      QL    +LE +R+ R G+ + +    FR+
Sbjct: 680  AGKLDPH--------------LVLD------QLRCNGVLEGIRICRQGFPNRVVFQEFRQ 719

Query: 1272 QFQVLDAPLLKKLMSTSEGIDERKAVEELLETLDLEKKAVAVGHSQVFLKAGVISRLEKQ 1331
            ++++L    + K       +D ++A   +++ L+L+     +G S+VF +AGV++ LE++
Sbjct: 720  RYEILTPNSIPKGF-----MDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEE 774

Query: 1332 REKLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKNVAVFLAVKDWPWWQLLGSL 1391
            R+  ++  I+ FQA C+G+L+R+ F K + +  A + +Q+N A +L +++W WW+L   +
Sbjct: 775  RDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKV 834

Query: 1392 QPLLSATIGTEQLRAKEEELTTLRRK-------LEKSEKLRNELRQNTDLLESKI---AD 1441
            +PLL  +   E++ AKEEEL  +R K       L + E L+++L      L+ ++    +
Sbjct: 835  KPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETE 894

Query: 1442 LTSDLADERFKGDVACQVLESERAERLQAFREVQELKSKHEQVQKK-----LGDVNKQLE 1496
            L ++  + R +     Q LE E    L+A  E +E + +H Q +KK     + ++ +QLE
Sbjct: 895  LCAEAEELRARLTAKKQELE-EICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLE 953

Query: 1497 EAQQKIQLNDLERNPTGGADEWQMRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQK 1556
            E +   Q   LE+  T    E +++    ++E E +    Q C  +L  E   +K LE +
Sbjct: 954  EEESARQKLQLEKVTT----EAKLK----KLEEEQIILEDQNC--KLAKE---KKLLEDR 1000

Query: 1557 LGE----LQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQ 1612
            + E    L    + +K +A +LK K   +  DLE+    L  ++ +  ELEK ++K +  
Sbjct: 1001 IAEFTTNLTEEEEKSKSLA-KLKNKHEAMITDLEER---LRREEKQRQELEKTRRKLE-- 1054

Query: 1613 LAQALGESVFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKREL 1672
                 G+S         ++ +   ++ ++ +L+ QL +KE+E      +VE     K   
Sbjct: 1055 -----GDST-------DLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMA 1102

Query: 1673 LGSPSLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLE----------------- 1715
            L      E+ ++ L+E    LES    + K + Q+ +  ++LE                 
Sbjct: 1103 LKKIRELESQISELQE---DLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ 1159

Query: 1716 QLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEK 1775
            +LR + E E+  +K+  +++ +  E +++++RQ   + + +L  QLEQ    K  +   K
Sbjct: 1160 ELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAK 1219

Query: 1776 QDLEGLIGTLCDQI-----GHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSK 1830
            Q LE   G L +++     G  D + ++      ++  A L ++Q+     E  +T ++ 
Sbjct: 1220 QTLENERGELANEVKVLLQGKGDSEHKR------KKVEAQLQELQVKFNEGERVRTELAD 1273

Query: 1831 E------ELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYR 1884
            +      EL+ V   L QS++K  +  K    L + L+     L+   R K  +  +L +
Sbjct: 1274 KVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQ 1333

Query: 1885 LQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQEQ 1944
            ++ EK    ++++E+++  + L ++   L AQ A    ++++    LE A++ K KLQ+ 
Sbjct: 1334 VEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKD 1393

Query: 1945 LQVAQMRIE--------------YLEQSTVDRAI-VSRQEAVICDLENKTEFQKVQIKRF 1989
            L+    R E               L+Q   D  + +  Q    C+LE K        K+F
Sbjct: 1394 LEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQ-------KKF 1446

Query: 1990 EVLVIRLRDSLIKMGEELSQAATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRC 2049
            + L+   +    K  EE  +A   E++ RE     + +   L   +EE ++++AE  R  
Sbjct: 1447 DQLLAEEKTISAKYAEERDRA---EAEAREK----ETKALSLARALEEAMEQKAELERLN 1499

Query: 2050 MELEKYVEELAAVRQTLQTDLETSIRRIADLQAALE-EVASSDSDTESVQTAVDCGSSGR 2108
             +    +E+L + +     D+  S+  +   + ALE +V    +  E ++  +      +
Sbjct: 1500 KQFRTEMEDLMSSKD----DVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAK 1555

Query: 2109 KEMD-NVSILSSQPEGSLQ 2126
              ++ N+  + +Q E  LQ
Sbjct: 1556 LRLEVNLQAMKAQFERDLQ 1574



 Score =  147 bits (371), Expect = 1e-34
 Identities = 152/716 (21%), Positives = 340/716 (47%), Gaps = 45/716 (6%)

Query: 1386 QLLGSLQPLLSATIGTEQLRAK-EEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTS 1444
            +L   ++ LL     +E  R K E +L  L+ K  + E++R EL      L+ ++ ++T 
Sbjct: 1228 ELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTG 1287

Query: 1445 DLADERFKGDVACQ---VLESERAERLQAFREVQE----LKSKHEQVQKKLGDVNKQLEE 1497
             L+    K     +    LES+  +  +  +E       L +K +QV+ +     +QLEE
Sbjct: 1288 LLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEE 1347

Query: 1498 AQQKIQLNDLERNPTGGADEWQMRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKL 1557
             ++    ++LE+         Q+    AQ+ +  ++K+++     L++    +++L++ L
Sbjct: 1348 EEEA--KHNLEK---------QIATLHAQVAD--MKKKMEDSVGCLETAEEVKRKLQKDL 1394

Query: 1558 GELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQAL 1617
              L   ++       +L++    L  +L+D  V L++Q+     LEKKQKKFD  LA+  
Sbjct: 1395 EGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEK 1454

Query: 1618 GESVFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPS 1677
              S      R++   E      +   L + L++  ++ ++L++  +  +    +L+ S  
Sbjct: 1455 TISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKD 1514

Query: 1678 LGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDRE 1737
                 V  L++    LE    E +    + E+ ++  E  + R E+ ++ MK   ++D +
Sbjct: 1515 DVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQ 1574

Query: 1738 DQEEELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVE 1797
             ++E+ E+ ++   +++ ++E +LE E +++ M +  ++ LE  +  L   I   + + +
Sbjct: 1575 GRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRD 1634

Query: 1798 KRLRRDLRRTHALLSDVQLLLGTMEDGKTSV------SKEELEKVHSQLEQSEAKCEEAL 1851
            + +++ LR+  A + D    L      +  +      ++++L+ + +++ Q + +   A 
Sbjct: 1635 EAIKQ-LRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAE 1693

Query: 1852 KTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDD---LNELMQ 1908
            + ++    + + +  E+ N +   +L  E+  RL+   A L + ++E+Q +   +N+ ++
Sbjct: 1694 RAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLK 1753

Query: 1909 KHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQ 1968
            K    I Q   D+   +    + E A+++  +  ++L+V    +E   +S   +A ++  
Sbjct: 1754 KANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKY-KASITAL 1812

Query: 1969 EAVICDLE----NKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQYY 2024
            EA I  LE    N+T+ ++   K+      +L+D L+++ +E   A     Q ++ +   
Sbjct: 1813 EAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNA----EQYKDQADKA 1868

Query: 2025 QRRLEELKADMEELVQ--REAEASRRCM--ELEKYVEELAAVRQTLQTDLETSIRR 2076
              RL++LK  +EE  +  + A ASRR +  ELE   E   A+ + + + L+  +RR
Sbjct: 1869 STRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREV-SSLKNKLRR 1923


>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
          Length = 1995

 Score =  374 bits (960), Expect = e-103
 Identities = 467/1939 (24%), Positives = 829/1939 (42%), Gaps = 241/1939 (12%)

Query: 497  GQSRDSDQAPEDRWYEAEKVWL-AQKDGFTLATVLKPDEGTADLP---AGRVRLWIDADK 552
            G    S  +P+  W     VW+ ++  GF  A +    E  A++    +GR RL +  D+
Sbjct: 37   GGGPGSGTSPQVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGR-RLRLPRDQ 95

Query: 553  TITEVDEEHVHRANPPELDQVEDLASLISVNESSVLNTLLQRYKAQLLHTCTGPDLIVLQ 612
                     + R NPP+  + ED+A L  +NE+SVL+ L +RY + L++T +G   +V+ 
Sbjct: 96   ---------IQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVIN 146

Query: 613  P--RGPSVPSA-GKVPKGR-RDGLPAHIGSMAQRAYWALLNQRRDQSIVALGWSGAGKTT 668
            P  + P    A  ++ +G+ R  +P H+ ++ + AY ++L  R DQSI+  G SGAGKT 
Sbjct: 147  PYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTE 206

Query: 669  CCEQVLEHLVGMAGSVDGRVSV-------EKIRATFTVLRAFGSVSMAHSRSATRFSMVM 721
              ++V+++L  +A S  GR           ++     +L AFG+     + +++RF   +
Sbjct: 207  NTKKVIQYLAHVASSPKGRKEPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFI 266

Query: 722  SLDFNATGRITAAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTELNLHQMAD 781
             ++F+  G I  A ++T LLEKSR  RQ + E +F +F Q+L G    L+ +L L   + 
Sbjct: 267  RINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSH 326

Query: 782  SSSFGMGVWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAAGACKV 841
                  G  S P  +++    F +   ++ +LG S  E  ++ R+++A+   G   A K 
Sbjct: 327  YRFLTNGPSSSPGQEREL---FQETLESLRVLGFSHEEIISMLRMVSAVLQFGNI-ALKR 382

Query: 842  GRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWGLEDEETSSGLK 901
             R         N AA+ L C    L    F   L  +  ++  G       D    +  K
Sbjct: 383  ERNTDQATMPDNTAAQKL-CRLLGLGVTDFSRAL--LTPRIKVG------RDYVQKAQTK 433

Query: 902  MTGVDCVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIM-VVDSPGFQNPRHQGKDRA 960
                  +E +A   Y+ LF  +V  +NR+        AS + ++D  GF+        + 
Sbjct: 434  EQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEI------FQL 487

Query: 961  ATFEELCHNYAHERLQLLFYQRTFVSTLQRYQEEGVP---VQFDLPDPSPGTTVAVVDQN 1017
             +FE+LC NY +E+LQ LF    FV   + YQ EG+P   + F L D  P   +     N
Sbjct: 488  NSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL-DLQPCIDLIERPAN 546

Query: 1018 PSQVRLPAGGGAQDARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTEGSSALRTC 1077
            P               GL  +LDEE     ++D   +E++     ++  G       R  
Sbjct: 547  PP--------------GLLALLDEECWFPKATDKSFVEKVA----QEQGGHPKFQRPRHL 588

Query: 1078 EQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSLFQARAKLP 1137
                   + H  G   V Y    WL +    L+  +   +LHQS         +  A++ 
Sbjct: 589  RDQADFSVLHYAG--KVDYKANEWLMKNMDPLND-NVAALLHQSTD-------RLTAEIW 638

Query: 1138 PVCRAVAGLEGTSQ--QALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMDALTSMIKRSR 1195
                 + GLE  S         R  R  F         +      K  +  L + +  + 
Sbjct: 639  KDVEGIVGLEQVSSLGDGPPGGRPRRGMF---------RTVGQLYKESLSRLMATLSNTN 689

Query: 1196 LHFIHCLVPNPVVESRSGQESPPPPQPGRDKPGAGGPLALDIPALRVQLAGFHILEALRL 1255
              F+ C+VPN   E R+G+  P               L LD      QL    +LE +R+
Sbjct: 690  PSFVRCIVPNH--EKRAGKLEPR--------------LVLD------QLRCNGVLEGIRI 727

Query: 1256 HRTGYADHMGLTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLETLDLEKKAVAVGH 1315
             R G+ + +    FR+++++L    + K       +D ++A E++++ L+L+     VG 
Sbjct: 728  CRQGFPNRILFQEFRQRYEILTPNAIPKGF-----MDGKQACEKMIQALELDPNLYRVGQ 782

Query: 1316 SQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKNVAV 1375
            S++F +AGV+++LE++R+  V+  IV FQAA +G+L+R+ F+K + ++ A + +Q+N A 
Sbjct: 783  SKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAA 842

Query: 1376 FLAVKDWPWWQLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEKLRNELRQNTDLL 1435
            +L ++ W WW+L   ++PLL  T   E L+A+ +EL  ++   ++S +   EL+     L
Sbjct: 843  YLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQL 902

Query: 1436 ESKIADLTSDLADERFKGDVACQVLESERAERLQAFREVQELKSKHEQVQKKLG---DVN 1492
            E + A L   L  E       C   E  R  RL A +  QEL+    +++ ++G   + +
Sbjct: 903  EEERARLAEQLRAEA----ELCAEAEETRG-RLAARK--QELELVVSELEARVGEEEECS 955

Query: 1493 KQLEEAQQKIQ--LNDLERN---PTGGADEWQMRFDCAQMENEFLRKRLQQCEERLDSEL 1547
            +Q++  ++++Q  + +LE +     G   + Q+     + + +   + L   E++     
Sbjct: 956  RQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLS 1015

Query: 1548 TARKELEQKLGEL--QSAYDGAK-KMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEK 1604
              RK LE +L E   Q+A +  K K  ++L+ K      D+ED    L  ++    ELEK
Sbjct: 1016 KERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDR---LRKEEKGRQELEK 1072

Query: 1605 KQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEM 1664
             +++ D       GES     L+E++ ++         +L+ QL +KE+E      + E 
Sbjct: 1073 LKRRLD-------GES---SELQEQMVEQQQRAE----ELRAQLGRKEEELQAALARAED 1118

Query: 1665 LQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQRFELE 1724
                + +LL S        A L E    LES  + + K + Q+ +  ++LE LR   E  
Sbjct: 1119 EGGARAQLLKSL---REAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELE-- 1173

Query: 1725 IERMKQMHQKDREDQEEELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEG-LIG 1783
                      D  D     +++R   ++ + +L+  LE+E    +  + E +   G  +G
Sbjct: 1174 ----------DTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALG 1223

Query: 1784 TLCDQI--GHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLE 1841
             L +Q+    R     ++ R  L    A +S+++  L +++  +    ++   ++  QL+
Sbjct: 1224 ELAEQLEQARRGKGAWEKTRLAL---EAEVSELRAELSSLQTARQE-GEQRRRRLELQLQ 1279

Query: 1842 QSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQD 1901
            + + +  +  + +      L+   +ELEN++   +  + +  RL  E +    ++ + Q+
Sbjct: 1280 EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQE 1339

Query: 1902 DLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIE-------- 1953
             L E  +    L ++  A   +   L+ QLEE    + +   +LQ AQ ++         
Sbjct: 1340 LLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEE 1399

Query: 1954 ---YLEQSTVDRAIVSRQ-EAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQ 2009
                LE     R   +R+ EA+   L  KTE      +    L   L D+ + + ++   
Sbjct: 1400 EAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQL 1459

Query: 2010 AATSESQQRESSQYYQRRLEELKADMEELVQREAEA---SRRCMELEKYVEELAAVRQTL 2066
             +T E +QR+  Q        +   +EE  + EAE      R + L + +EE    R+ L
Sbjct: 1460 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1519

Query: 2067 QTDLETSIRRIADLQAALEEVASSDSDT-ESVQTAVDCGSSGRKEMDNVSILSSQPEGSL 2125
            +       R+   L+A LE + SS  D  +SV           +  +++    ++ E  L
Sbjct: 1520 E-------RQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDEL 1572

Query: 2126 QSWLSCTLSLATDTMRTPSRQSATSSRILSPRINEEAGDTERTQSALALSRARSTNVHSK 2185
             +     L L      T         R L  R  +EAG+  R Q A             K
Sbjct: 1573 TAAEDAKLRLEV----TVQALKTQHERDLQGR--DEAGEERRRQLA-------------K 1613

Query: 2186 TSGDKPVSPHFVRRQKYCHFGDGEVLAVQRKSTERLEPASSPLASRSTNTSPLSRE--KL 2243
               D  V     R+Q+         +A ++K    LE   + +AS         ++  K+
Sbjct: 1614 QLRDAEVERDEERKQRTL------AVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKM 1667

Query: 2244 PSPSAALSEFVEGLRRKRAQ------RGQGSTLGLEDWPTLPIYQTTGASTLRRGRAGSD 2297
             +    L   VE  R  R +        +    GLE    L + +   AS   R +A  D
Sbjct: 1668 QAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEA-EVLRLQEELAASDRARRQAQQD 1726

Query: 2298 ---------EGNLSLRVGAKSPLEIEGAAGGLLRSTSLKCISSDGVGG---TTLLPEKSK 2345
                      GNLS     +   ++EG  G L      +  +S+ +       LL  +S 
Sbjct: 1727 RDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESL 1786

Query: 2346 TQFSSCESLLESRPSMGRK 2364
            T   S E    ++   GR+
Sbjct: 1787 TTELSAERSFSAKAESGRQ 1805



 Score =  147 bits (372), Expect = 1e-34
 Identities = 177/762 (23%), Positives = 330/762 (43%), Gaps = 98/762 (12%)

Query: 1406 AKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESERA 1465
            A E E++ LR +L   +  R E  Q    LE ++ ++     D       A + L+  +A
Sbjct: 1245 ALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQA 1304

Query: 1466 ERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPTGGADEWQMRFDCA 1525
            E       + E +SK  ++ K+L     QL +AQ+ +Q     +   G       R    
Sbjct: 1305 ELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGS------RVRAM 1358

Query: 1526 QMENEFLRKRLQQ---CEERLDSELTA--------RKELEQKLGELQSAYDGAKKMAHQ- 1573
            + E   LR++L++     ER   EL          R+  E++ G L++  +  ++ A + 
Sbjct: 1359 EAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREA 1418

Query: 1574 ----------------LKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQAL 1617
                            L+R    L  +L+D  + LE Q+     LEKKQ+KFD  LA+  
Sbjct: 1419 EALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEK 1478

Query: 1618 GESVFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPS 1677
               +     RE+   E          L + L+++++   +L++Q   L+     LL S  
Sbjct: 1479 AAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKD 1538

Query: 1678 LGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDRE 1737
                 V  L+      E +A + +   ++ E+ +   E  + R E+ ++ +K  H++D +
Sbjct: 1539 DVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQ 1598

Query: 1738 DQEEELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVE 1797
             ++E  E+ R+   K+L   E++ ++E +++ + +  ++ LEG +  L  Q+       E
Sbjct: 1599 GRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKE 1658

Query: 1798 KRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCE----EALKT 1853
            + +++ LR+  A + +   L   +E+ +TS      E++ SQ  +SE + +    E L+ 
Sbjct: 1659 EAVKQ-LRKMQAQMKE---LWREVEETRTS-----REEIFSQNRESEKRLKGLEAEVLRL 1709

Query: 1854 QKVLTA----------DLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDL 1903
            Q+ L A          D + M  E+ N   +K+ + E+  +L+     L + ++E+Q + 
Sbjct: 1710 QEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNS 1769

Query: 1904 NELMQKHKDLIAQSAADIGQIQELQLQLE-----EAKKEKHKLQEQLQVAQMRIEYLEQS 1958
              L  +++ L+ Q       ++ L  +L       AK E  + Q + Q+ ++R    E+ 
Sbjct: 1770 ELLNDRYRKLLLQ-------VESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEED 1822

Query: 1959 TVDRAIVSRQEAVICDLENK---TEFQKVQIKRFEVLV--------IRLRDSLIKMGEEL 2007
               RA   R +  I  LE+K    E Q  Q  R  +L          RL++ ++++ EE 
Sbjct: 1823 AGARA---RHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER 1879

Query: 2008 SQAATSESQQRESSQYYQRRLEELKADMEELVQR--EAEASRRCM--ELEKYVE------ 2057
              A     Q R+  +    R+++LK  +EE  +    A+A RR +  ELE   E      
Sbjct: 1880 RVA----DQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMN 1935

Query: 2058 -ELAAVRQTLQTDLETSIRRIADLQAALEEVASSDSDTESVQ 2098
             E+  +R  L+    T   R       LEE  +SD + E  Q
Sbjct: 1936 REVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQ 1977



 Score = 33.1 bits (74), Expect = 3.6
 Identities = 35/132 (26%), Positives = 54/132 (40%), Gaps = 21/132 (15%)

Query: 357  KTSQVQGELGDDLRMGEKAGELRSTTGKAGESWDKKEKMGQPQGKSGNAGEARSQTEKGC 416
            K +Q + +L  + R    +G+L     K       KE + Q + +   A + R Q EKG 
Sbjct: 1839 KLAQAEEQLEQETRERILSGKLVRRAEKR-----LKEVVLQVEEERRVADQLRDQLEKGN 1893

Query: 417  EAPKEVSTMVESPAAPGKGGWPGSRGQEAEEPCSRAGDGAGALETELEGPSQPALEKDAE 476
               K++   +E                EAEE  SRA  G   L+ ELE  ++ A   + E
Sbjct: 1894 LRVKQLKRQLE----------------EAEEEASRAQAGRRRLQRELEDVTESAESMNRE 1937

Query: 477  RPRIRKENQDGP 488
               +R   + GP
Sbjct: 1938 VTTLRNRLRRGP 1949


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
            sapiens]
          Length = 1937

 Score =  372 bits (956), Expect = e-102
 Identities = 410/1743 (23%), Positives = 779/1743 (44%), Gaps = 236/1743 (13%)

Query: 503  DQAPEDRWYEAEKVWLAQK--DGFTLATVLKPDEGTA-----DLPAGRVRLWIDADKTIT 555
            + AP  R  E E++    K  D  T   V +P E            G+V +  +   T+T
Sbjct: 14   EAAPYLRKSEKERIEAQNKPFDAKTSVFVAEPKESYVKSTIQSKEGGKVTVKTEGGATLT 73

Query: 556  EVDEEHVHRANPPELDQVEDLASLISVNESSVLNTLLQRYKAQLLHTCTGPDLIVLQPRG 615
             V E+ V   NPP+ D++ED+A +  ++E  VL  L +RY A +++T +G   + + P  
Sbjct: 74   -VREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYK 132

Query: 616  ------PSVPSAGKVPKGRRDGLPAHIGSMAQRAYWALLNQRRDQSIVALGWSGAGKTTC 669
                  P V +A +  K  R   P HI S++  AY  +L  R +QSI+  G SGAGKT  
Sbjct: 133  WLPVYKPEVVAAYRGKK--RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVN 190

Query: 670  CEQVLEHLVGMA----------GSVDGRVSVEKIRATFTVLRAFGSVSMAHSRSATRFSM 719
             ++V+++   +A          G + G +  + I A   +L AFG+     + +++RF  
Sbjct: 191  TKRVIQYFATIAVTGEKKKDESGKMQGTLEDQIISAN-PLLEAFGNAKTVRNDNSSRFGK 249

Query: 720  VMSLDFNATGRITAAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTELNLHQM 779
             + + F  TG++ +A ++T LLEKSRV  Q + E ++ +F Q+ +    DL   L +   
Sbjct: 250  FIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTN 309

Query: 780  ADSSSF-GMGVWSKP--EDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAA 836
                +F   G  + P  +D+++  A       A+++LG +  E+ +++++  A+ H G  
Sbjct: 310  PYDYAFVSQGEITVPSIDDQEELMAT----DSAIDILGFTPEEKVSIYKLTGAVMHYG-- 363

Query: 837  GACKVGRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWGLEDEET 896
                +  KQ  R E     AE  G E  +        +   +++ + +   + G  +E  
Sbjct: 364  ---NMKFKQKQREE----QAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVG--NEYV 414

Query: 897  SSGLKMTGV-DCVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQ 955
            + G  +  V + V  +A  +Y+++F  +V+ IN+   +       I V+D  GF+     
Sbjct: 415  TKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFN 474

Query: 956  GKDRAATFEELCHNYAHERLQLLFYQRTFVSTLQRYQEEGVPVQFDLPDPSPGTTVAVVD 1015
                  + E+LC N+ +E+LQ  F    FV   + Y++EG+   F          + +++
Sbjct: 475  ------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIE 528

Query: 1016 QNPSQVRLPAGGGAQDARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTEGSSALR 1075
            +                 G+F +L+EE     ++D+    +L      K A  +    ++
Sbjct: 529  K---------------PLGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKVVK 573

Query: 1076 TCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQ-SKREELRSLFQ--A 1132
              +      + H  G   V Y++TGWL + K  L+  D    L+Q S  + L SLF   A
Sbjct: 574  G-KAEAHFSLIHYAG--TVDYNITGWLDKNKDPLN--DTVVGLYQKSAMKTLASLFSTYA 628

Query: 1133 RAKLPPVCRAVAGLEGTSQQALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMDALTSMIK 1192
             A+     +  A  +G+S Q              +++A+ R+         ++ L + ++
Sbjct: 629  SAEADSSAKKGAKKKGSSFQ--------------TVSALFRE--------NLNKLMTNLR 666

Query: 1193 RSRLHFIHCLVPNPVVESRSGQESPPPPQPGRDKPGAGGPLALDIPALRVQLAGFHILEA 1252
             +  HF+ C++PN   E+++                   P A++   +  QL    +LE 
Sbjct: 667  STHPHFVRCIIPN---ETKT-------------------PGAMEHELVLHQLRCNGVLEG 704

Query: 1253 LRLHRTGYADHMGLTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLETLDLEKKAVA 1312
            +R+ R G+   +    F+++++VL+A  + +     + ID +KA E+LL ++D++     
Sbjct: 705  IRICRKGFPSRILYGDFKQRYKVLNASAIPE----GQFIDSKKASEKLLASIDIDHTQYK 760

Query: 1313 VGHSQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKN 1372
             GH++VF KAG++  LE+ R++ ++Q I   QA C+GFL R E++K+  RR A  CIQ N
Sbjct: 761  FGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYN 820

Query: 1373 VAVFLAVKDWPWWQLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEKLRNELRQNT 1432
            V  F+ VK WPW +L   ++PLL +    +++   +EE    + +L KSE  R EL +  
Sbjct: 821  VRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKM 880

Query: 1433 DLLESKIADLTSDL---ADERFKGDVACQVLESERAERLQAFREVQELKSKHEQVQKKLG 1489
              L  +  DL   +   AD     +  C+ L   + +     +EV E   + E++  +L 
Sbjct: 881  VTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELT 940

Query: 1490 DVNKQLEE--AQQKIQLNDLE-----------------RNPT---GGADEWQMRFD---- 1523
               ++LE+  ++ K  ++DLE                 +N T    G DE   +      
Sbjct: 941  AKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKK 1000

Query: 1524 CAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTC 1583
              Q  ++     LQ  E++++    A+ +LEQ++ +L+ + +  KK+   L+R    L  
Sbjct: 1001 ALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEG 1060

Query: 1584 DL----EDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRW 1639
            DL    E T  +  ++Q  + +LEKK+ +    +++   E   E  L++K+ +    +  
Sbjct: 1061 DLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIE- 1119

Query: 1640 ELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSALE 1699
            ELG+      + E E +   +  +   D  REL             + ERL +   +   
Sbjct: 1120 ELGE------EIEAERASRAKAEKQRSDLSREL-----------EEISERLEEAGGATSA 1162

Query: 1700 QQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDRED-------QEEELEDVRQSCQK 1752
            Q ++  ++E   ++L +  +   L+ E M    +K   D       Q + L+ V+Q  +K
Sbjct: 1163 QVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEK 1222

Query: 1753 RLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGH--RDFDVEKRLRRDLRRTHAL 1810
               +L+M+ +      + +   K +LE +  +L DQ+       + ++RL  DL    A 
Sbjct: 1223 EKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRAR 1282

Query: 1811 LSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELEN 1870
            L                  + E  +   QL++ +A   +  ++++  T  +E +  +LE 
Sbjct: 1283 L------------------QTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEE 1324

Query: 1871 MTRNKSLVDEQLYRLQFEKADLLKRIDEDQD---DLNELMQKHKDLIAQ--SAADIGQIQ 1925
             T+ K+ +   L   + +   L ++ +E+Q+   +L   + K    +AQ  +  +   IQ
Sbjct: 1325 ETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQ 1384

Query: 1926 ELQLQLEEAKKEKHKLQEQLQVAQMRIEYLE-------------QSTVDRAI--VSRQEA 1970
              + +LEEAKK   KL ++LQ A+  +E +              Q+ V+  +  V R  A
Sbjct: 1385 RTE-ELEEAKK---KLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNA 1440

Query: 1971 VICDLENK-TEFQKVQI---KRFEVLVIRLRDSLIK---MGEELSQAATSESQQRESSQY 2023
                L+ K   F KV     +++E     L  S  +   +  EL +      +  +  + 
Sbjct: 1441 ACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLET 1500

Query: 2024 YQRRLEELKADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAA 2083
             +R  + L+ ++ +L ++ AE  ++  ELEK  +++   +  +Q  LE +    A L+  
Sbjct: 1501 LRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEA---EASLEHE 1557

Query: 2084 LEEVASSDSDTESVQTAVDCGSSGR-KEMDNVSILSSQPEGSLQSWLSCTLSLATDTMRT 2142
              ++     +   V++ VD   + + +E+D +    ++   ++QS L   +    D +R 
Sbjct: 1558 EGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRV 1617

Query: 2143 PSR 2145
              +
Sbjct: 1618 KKK 1620



 Score =  122 bits (307), Expect = 3e-27
 Identities = 138/679 (20%), Positives = 304/679 (44%), Gaps = 60/679 (8%)

Query: 1405 RAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESER 1464
            R+ E++++ L+ K E+ ++L N+L      L+++  + +  L +   K  +  Q+  S++
Sbjct: 1253 RSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDE---KDALVSQLSRSKQ 1309

Query: 1465 AERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQKIQL--NDLERNPTGGADEWQM-- 1520
            A   Q    ++ELK + E+  K    +   L+ ++    L     E    G A+  +   
Sbjct: 1310 ASTQQ----IEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALS 1365

Query: 1521 --RFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKC 1578
                + AQ   ++    +Q+ EE  +    A+K+L Q+L E +   +        L++  
Sbjct: 1366 KANSEVAQWRTKYETDAIQRTEELEE----AKKKLAQRLQEAEEHVEAVNAKCASLEKTK 1421

Query: 1579 HHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVR 1638
              L  ++ED  + +E   +    L+KKQ+ FD  L++   +    +   E   +E+ S+ 
Sbjct: 1422 QRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLS 1481

Query: 1639 WELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSAL 1698
             EL +++   ++   +   L+++ + LQ    +L    + G   +  L++   ++E    
Sbjct: 1482 TELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKC 1541

Query: 1699 EQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQLE 1758
            E Q    + E +++  E    R +LE+ ++K    +   +++EE++ ++++  + +  ++
Sbjct: 1542 EIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQ 1601

Query: 1759 MQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLL 1818
              L+ E   +   L  K+ +EG +  +  Q+ H +    + L R+ R T  +L + QL L
Sbjct: 1602 STLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESL-RNYRNTQGILKETQLHL 1660

Query: 1819 GTMEDGKTSVSKE-------------ELEKVHSQLEQSEAKCEEA--------------- 1850
                 G+  + ++             E+E++ + LEQ+E   + A               
Sbjct: 1661 DDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLH 1720

Query: 1851 ------LKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLN 1904
                  + T+K L  D+  + SE+E + +     +E+  +   + A + + + ++QD   
Sbjct: 1721 TQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSA 1780

Query: 1905 ELMQKHKDLIAQSAADI-GQIQEL-QLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDR 1962
             L +  K+L  Q+  D+  ++ E  QL L+  KK+  KL+ +++  +  +E  EQ     
Sbjct: 1781 HLERMKKNL-EQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVEN-EQKRNAE 1838

Query: 1963 AI--VSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRES 2020
            A+  + + E  + +L  +TE  +  + R + LV +L+  +     +  +A    +     
Sbjct: 1839 AVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNANLSK 1898

Query: 2021 SQYYQRRLEEL--KADMEE 2037
             +  Q  LEE   +AD+ E
Sbjct: 1899 FRKLQHELEEAEERADIAE 1917



 Score =  118 bits (295), Expect = 9e-26
 Identities = 161/769 (20%), Positives = 335/769 (43%), Gaps = 105/769 (13%)

Query: 1402 EQLRAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLE 1461
            EQ +    +L   +RKLE   KL  E   +T  +E+    L   L  + F+       +E
Sbjct: 1042 EQEKKLRMDLERAKRKLEGDLKLAQE---STMDMENDKQQLDEKLEKKEFEISNLISKIE 1098

Query: 1462 SERAERLQAFREVQELKSKHEQV--------------QKKLGDVNKQLEEAQQKIQLNDL 1507
             E+A  +Q  ++++EL+++ E++              +K+  D++++LEE  ++++    
Sbjct: 1099 DEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLE---- 1154

Query: 1508 ERNPTGGADEWQMRFDCAQMENEF--LRKRLQQCEERLDSELTA-RKELEQKLGELQSAY 1564
                 GGA   Q+  +  + E EF  LR+ L++   + ++ + A RK+    + EL    
Sbjct: 1155 ---EAGGATSAQVELN-KKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQI 1210

Query: 1565 DGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEK 1624
            D  +++  +L+++   L  + +D     E        LEK  +  + Q+++   +   ++
Sbjct: 1211 DNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQ 1270

Query: 1625 GLREKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKREL---LGSPSLGEN 1681
             L   +T +   ++ E G+  +QL +K+   SQL +  +       EL   L   +  +N
Sbjct: 1271 RLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKN 1330

Query: 1682 CVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEE 1741
             +A   +         L +++ + +QE    +L++   +   E+ + +  ++ D   + E
Sbjct: 1331 ALAHALQS--SRHDCDLLREQYEEEQEGKA-ELQRALSKANSEVAQWRTKYETDAIQRTE 1387

Query: 1742 ELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLR 1801
            ELE+ ++   +RL + E  +E    +   +   KQ L+  +               + L 
Sbjct: 1388 ELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEV---------------EDLM 1432

Query: 1802 RDLRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADL 1861
             D+ R++A  + +        D K     + L +   + E+++A+ E + K  + L+ +L
Sbjct: 1433 LDVERSNAACAAL--------DKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTEL 1484

Query: 1862 ESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADI 1921
              + +  E        +  +   LQ E +DL ++I E    ++EL +K K  + Q   +I
Sbjct: 1485 FKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHEL-EKIKKQVEQEKCEI 1543

Query: 1922 ---------------GQIQELQLQLEEAKKE-------KHKLQEQLQVAQMRIEYLEQST 1959
                           G+I  +QL+L + K E       K +  +QL+    R+    QST
Sbjct: 1544 QAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQST 1603

Query: 1960 VDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRE 2019
            +D  I SR +A+    + + +  +++I+        L  +     E L     ++   +E
Sbjct: 1604 LDAEIRSRNDALRVKKKMEGDLNEMEIQ--------LNHANRLAAESLRNYRNTQGILKE 1655

Query: 2020 SSQYYQRRLEELKADMEELVQREAEASRRCMELEKYVEEL-AAVRQTLQTDLETSIRRIA 2078
            +    Q  L++     E+L ++ A   RR   L+  +EEL A + QT ++      R+IA
Sbjct: 1656 T----QLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERS------RKIA 1705

Query: 2079 DLQAALEEVASSDSDTESVQTAVDCGSSGRKEMDN-VSILSSQPEGSLQ 2126
            +     +E+  +    + + T      + +K+++N VS L S+ E  +Q
Sbjct: 1706 E-----QELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQ 1749



 Score = 89.4 bits (220), Expect = 4e-17
 Identities = 155/768 (20%), Positives = 314/768 (40%), Gaps = 96/768 (12%)

Query: 1272 QFQVLDAPLLKK----LMSTSEGIDERKAVEELLETLDLEKKAVAVGHSQVFLKAGVISR 1327
            Q + + A L KK    +    E ID  + V++ LE    EK  + +    +   A  IS+
Sbjct: 1187 QHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEK---EKSELKMETDDLSSNAEAISK 1243

Query: 1328 LEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKNVAVFLAVKDWPWWQL 1387
             +   EK+        +       +++E ++  I  L AQ  +      L  +   + + 
Sbjct: 1244 AKGNLEKMCRS----LEDQVSELKTKEEEQQRLINDLTAQRAR------LQTEAGEYSRQ 1293

Query: 1388 LGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEKLRNEL-------RQNTDLLESK-- 1438
            L     L+S    ++Q  A  +++  L+ +LE+  K +N L       R + DLL  +  
Sbjct: 1294 LDEKDALVSQLSRSKQ--ASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYE 1351

Query: 1439 ------------IADLTSDLADER--FKGDVACQVLESERAERLQAFREVQELKSKHEQV 1484
                        ++   S++A  R  ++ D   +  E E A++  A R +QE +   E V
Sbjct: 1352 EEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR-LQEAEEHVEAV 1410

Query: 1485 QKKLGDVNKQLEEAQQKIQ--LNDLERNPTGGA--DEWQMRFDCAQMENEFLRKRLQQCE 1540
              K   + K  +  Q +++  + D+ER+    A  D+ Q  FD    E    +++ ++ +
Sbjct: 1411 NAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSE---WKQKYEETQ 1467

Query: 1541 ERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNH 1600
              L++     + L  +L ++++ Y+ +      L+R+  +L  ++ D    +     + H
Sbjct: 1468 AELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIH 1527

Query: 1601 ELEK-----KQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEA 1655
            ELEK     +Q+K ++Q A    E+  E     K+ +    +     ++ +++ +K++E 
Sbjct: 1528 ELEKIKKQVEQEKCEIQAALEEAEASLEHE-EGKILRIQLELNQVKSEVDRKIAEKDEEI 1586

Query: 1656 SQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLE 1715
             QLK+    + +  +  L +     N    +K+++       L + +IQ    N +    
Sbjct: 1587 DQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKM----EGDLNEMEIQLNHANRLAAES 1642

Query: 1716 QLRQRFELEIERMKQMHQKD----REDQEEELEDVRQSC---QKRLHQLEMQLEQEYEEK 1768
                R    I +  Q+H  D    +ED +E+L  V +     Q  + +L   LEQ    +
Sbjct: 1643 LRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSR 1702

Query: 1769 QMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDV-QLLLGTMEDGKTS 1827
            ++   E  D    +  L  Q      + +K+L  D+ +  + + +V Q      E  K +
Sbjct: 1703 KIAEQELLDASERVQLLHTQ-NTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKA 1761

Query: 1828 VS----------KEE-----LEKVHSQLEQSEAKCEEAL------------KTQKVLTAD 1860
            ++          KE+     LE++   LEQ+    +  L            K  + L A 
Sbjct: 1762 ITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEAR 1821

Query: 1861 LESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAAD 1920
            +  +  E+EN  +  +   + L + +    +L  + +ED+ ++  L      L A+  + 
Sbjct: 1822 VRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSY 1881

Query: 1921 IGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQ 1968
              Q +E + Q      +  KLQ +L+ A+ R +  E       + SR+
Sbjct: 1882 KRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSRE 1929



 Score = 83.2 bits (204), Expect = 3e-15
 Identities = 113/536 (21%), Positives = 227/536 (42%), Gaps = 77/536 (14%)

Query: 1384 WWQLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLT 1443
            W Q     Q  L A+   ++ R+   EL  ++   E+S      LR+    L+ +I+DLT
Sbjct: 1459 WKQKYEETQAELEAS--QKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLT 1516

Query: 1444 SDLAD--------ERFKGDVACQVLESERAERLQAFREVQELKSKHEQ-----VQKKLGD 1490
              +A+        E+ K  V     E E+ E +QA  E  E   +HE+     +Q +L  
Sbjct: 1517 EQIAEGGKQIHELEKIKKQV-----EQEKCE-IQAALEEAEASLEHEEGKILRIQLELNQ 1570

Query: 1491 VNKQLEE--AQQKIQLNDLERNPTGGADEWQMRFDCAQMENEFLRKRLQQCEERLDSELT 1548
            V  +++   A++  +++ L+RN T   +  Q   D        +R R        +  L 
Sbjct: 1571 VKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAE------IRSR--------NDALR 1616

Query: 1549 ARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKK 1608
             +K++E  L E++   + A ++A +  R   +    L++T + L++      +L++    
Sbjct: 1617 VKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKE---- 1672

Query: 1609 FDLQLAQALGESVFEKGLREKVTQENTSVRWE-LGQLQQQLKQKEQEASQLKQQVEMLQD 1667
               QLA      + E+  R  + Q      W  L Q ++  K  EQE     ++V++L  
Sbjct: 1673 ---QLA------IVER--RANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHT 1721

Query: 1668 HKRELLGSPSLGENCVAGLKERLWK-LESSALEQQKIQSQQENTIKQLEQLR--QRFELE 1724
                L+ +    EN V+ L+  + + ++ S   ++K +    +     E+L+  Q     
Sbjct: 1722 QNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAH 1781

Query: 1725 IERMKQMHQKDREDQEEELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGT 1784
            +ERMK+  ++  +D +  L++  Q   K   +   +LE    E +  +  +Q        
Sbjct: 1782 LERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQK------- 1834

Query: 1785 LCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSKEEL-EKVHSQLEQS 1843
                   R+ +  K LR+  RR        +L   T ED K  +  ++L +K+ ++++  
Sbjct: 1835 -------RNAEAVKGLRKHERRVK------ELTYQTEEDRKNVLRLQDLVDKLQAKVKSY 1881

Query: 1844 EAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDED 1899
            + + EEA +      +    +  ELE       + + Q+ +L+ +  ++  +I  +
Sbjct: 1882 KRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKISAE 1937


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score =  372 bits (955), Expect = e-102
 Identities = 375/1672 (22%), Positives = 752/1672 (44%), Gaps = 221/1672 (13%)

Query: 542  GRVRLWIDADKTITEVDEEHVHRANPPELDQVEDLASLISVNESSVLNTLLQRYKAQLLH 601
            G+V    +  KT+T V E+ V + NPP+ D++ED+A L  ++E +VL  L  RY + +++
Sbjct: 57   GKVTAETEYGKTVT-VKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNLKDRYGSWMIY 115

Query: 602  TCTGPDLIVLQPRG------PSVPSAGKVPKGRRDGLPAHIGSMAQRAYWALLNQRRDQS 655
            T +G   + + P        P V +A +  K  R   P HI S++  AY  +L  R +QS
Sbjct: 116  TYSGLFCVTVNPYKWLPVYTPEVVAAYRGKK--RSEAPPHIFSISDNAYQYMLTDRENQS 173

Query: 656  IVALGWSGAGKTTCCEQVLEHLVGMAGSVD--------GRVSVE-KIRATFTVLRAFGSV 706
            I+  G SGAGKT   ++V+++   +A   D        G+ ++E +I      L AFG+ 
Sbjct: 174  ILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPGKGTLEDQIIQANPALEAFGNA 233

Query: 707  SMAHSRSATRFSMVMSLDFNATGRITAAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGL 766
                + +++RF   + + F ATG++ +A ++T LLEKSRV  Q + E ++ +F Q+L+  
Sbjct: 234  KTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHIFYQILSNK 293

Query: 767  DLDLRTELNLHQMADSSSF---GMGVWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAV 823
              +L   L +       +F   G    +  +D ++  A       A ++LG +  E+ ++
Sbjct: 294  KPELLDMLLITNNPYDYAFISQGETTVASIDDAEELMAT----DNAFDVLGFTSEEKNSM 349

Query: 824  WRVLAAIYHLGAAGACKVGRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMT 883
            +++  AI H G            M+F+      +A     EE + + +   L        
Sbjct: 350  YKLTGAIMHFGN-----------MKFKLKQREEQAEPDGTEEADKSAYLMGLNSADLLKG 398

Query: 884  FGPSRWGLEDEETSSGLKMTGVDCVEG-MASGLYQELFAAVVSLINRSFSSHHLSMASIM 942
                R  + +E  + G  +  V    G +A  +Y+ +F  +V+ IN +  +       I 
Sbjct: 399  LCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATLETKQPRQYFIG 458

Query: 943  VVDSPGFQNPRHQGKDRAATFEELCHNYAHERLQLLFYQRTFVSTLQRYQEEGVPVQFDL 1002
            V+D  GF+           +FE+LC N+ +E+LQ  F    FV   + Y++EG+   F  
Sbjct: 459  VLDIAGFEIFDFN------SFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFID 512

Query: 1003 PDPSPGTTVAVVDQNPSQVRLPAGGGAQDARGLFWVLDEEVHVEGSSDSVVLERLCAAFE 1062
                    + ++++                 G+  +L+EE     ++D     +L     
Sbjct: 513  FGMDLQACIDLIEK---------------PMGIMSILEEECMFPKATDMTFKAKLFDNHL 557

Query: 1063 KKGAGTEGSSALRTCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQSK 1122
             K A  +    ++  +      + H  G   V Y++ GWL + K  L+  +    L+Q  
Sbjct: 558  GKSANFQKPRNIKG-KPEAHFSLIHYAGI--VDYNIIGWLQKNKDPLN--ETVVGLYQKS 612

Query: 1123 REELRSLFQARAKLPPVCRAVAGLEGTSQQALQRSRMVRRTFASSLAAVRRKAPCSQIKL 1182
              +L S   A           AG +   ++   +++  + +   +++A+ R+        
Sbjct: 613  SLKLLSTLFAN---------YAGADAPIEKGKGKAK--KGSSFQTVSALHRE-------- 653

Query: 1183 QMDALTSMIKRSRLHFIHCLVPNPVVESRSGQESPPPPQPGRDKPGAGGPLALDIPALRV 1242
             ++ L + ++ +  HF+ C++PN   E++S                   P  +D P +  
Sbjct: 654  NLNKLMTNLRSTHPHFVRCIIPN---ETKS-------------------PGVMDNPLVMH 691

Query: 1243 QLAGFHILEALRLHRTGYADHMGLTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLE 1302
            QL    +LE +R+ R G+ + +    FR+++++L+   + +     + ID RK  E+LL 
Sbjct: 692  QLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAIPE----GQFIDSRKGAEKLLS 747

Query: 1303 TLDLEKKAVAVGHSQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIR 1362
            +LD++      GH++VF KAG++  LE+ R++ +S+ I   QA  +G L+R E+KKL  R
Sbjct: 748  SLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLARMEYKKLLER 807

Query: 1363 RLAAQCIQKNVAVFLAVKDWPWWQLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSE 1422
            R +   IQ N+  F+ VK+WPW +L   ++PLL +    +++ + +EE T L+  LEKSE
Sbjct: 808  RDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAEREKEMASMKEEFTRLKEALEKSE 867

Query: 1423 KLRNELRQN-TDLLESK-------------IADLTSDLADERFKGDVACQVLESERAERL 1468
              R EL +    LL+ K             +AD   +  D+  K  +  +    E  ERL
Sbjct: 868  ARRKELEEKMVSLLQEKNDLQLQVQAEQDNLAD-AEERCDQLIKNKIQLEAKVKEMNERL 926

Query: 1469 QAFREVQ-ELKSKHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPT-----------GGAD 1516
            +   E+  EL +K  +++ +  ++ + +++ +  +   + E++ T            G D
Sbjct: 927  EDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLD 986

Query: 1517 EWQMRF----DCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAH 1572
            E   +        Q  ++     LQ  E+++++   A+ +LEQ++ +L+ + +  KK+  
Sbjct: 987  EIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRM 1046

Query: 1573 QLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQ 1632
             L+R    L  DL+ T   + + ++   +L+++ KK D +L         E+ L  ++ +
Sbjct: 1047 DLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQK 1106

Query: 1633 ENTSVRWELGQLQQQLKQK-------EQEASQLKQQVEMLQDHKRELLGSPSLGENCVAG 1685
            +   ++  + +L+++L+ +       E+  S L +++E + +   E  G+ S+       
Sbjct: 1107 KLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSV------- 1159

Query: 1686 LKERLWKLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQ---KDREDQEEE 1742
                  ++E +   + + Q  +    + LE+   + E     +++ H     +  +Q + 
Sbjct: 1160 ------QIEMNKKREAEFQKMR----RDLEEATLQHEATAAALRKKHADSVAELGEQIDN 1209

Query: 1743 LEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLR- 1801
            L+ V+Q  +K   + +++L+      + ++  K +LE +  TL DQ+       E+  R 
Sbjct: 1210 LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRS 1269

Query: 1802 -RDLRRTHA-----------LLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEE 1849
              DL    A            L + + L+  +  GK + + ++LE +  QLE+ E K + 
Sbjct: 1270 VNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYT-QQLEDLKRQLEE-EVKAKN 1327

Query: 1850 AL-KTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQ 1908
            AL    +    D + +  + E  T  K+ +   L +   E A    + + D     E ++
Sbjct: 1328 ALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELE 1387

Query: 1909 KHKDLIAQSAADIGQ-IQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAIVSR 1967
            + K  +AQ   +  + ++ +  +    +K KH+LQ +++   + +E    +    A+  +
Sbjct: 1388 EAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVE--RSNAAAAALDKK 1445

Query: 1968 Q---EAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQYY 2024
            Q   + ++ + + K E  + +++  +     L   L K+         +  +  E  + +
Sbjct: 1446 QRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKL-------KNAYEESLEHLETF 1498

Query: 2025 QRRLEELKADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIAD----- 2079
            +R  + L+ ++ +L ++   + +   ELEK  ++L A +  LQ+ LE +   +       
Sbjct: 1499 KRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKI 1558

Query: 2080 LQAALE----------EVASSDSDTE-----------SVQTAVDCGSSGRKE 2110
            L+A LE          ++A  D + E           S+QT++D  +  R E
Sbjct: 1559 LRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNE 1610



 Score =  136 bits (342), Expect = 3e-31
 Identities = 155/762 (20%), Positives = 336/762 (44%), Gaps = 92/762 (12%)

Query: 1409 EELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESE----R 1464
            E++  L+R  +K EK ++E +   D + S +  +    A+     +  C+ LE +    R
Sbjct: 1205 EQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL----EKMCRTLEDQMNEHR 1260

Query: 1465 AERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQKI------------QLNDLER--- 1509
            ++  +  R V +L S+  ++Q + G++++QL+E +  I            QL DL+R   
Sbjct: 1261 SKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLE 1320

Query: 1510 ------NPTGGADEWQMRFDCAQMENEF-----LRKRLQQCEERLDSELT---------- 1548
                  N    A +   R DC  +  ++      +  LQ+   + +SE+           
Sbjct: 1321 EEVKAKNALAHALQ-SARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDA 1379

Query: 1549 ---------ARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRN 1599
                     A+K+L Q+L E + A +        L++  H L  ++ED  V +E   +  
Sbjct: 1380 IQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAA 1439

Query: 1600 HELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEASQLK 1659
              L+KKQ+ FD  LA+   +    +   E   +E  S+  EL +L+   ++  +     K
Sbjct: 1440 AALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFK 1499

Query: 1660 QQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQ 1719
            ++ + LQ+   +L          +  L++   +LE+  +E Q    + E +++  E    
Sbjct: 1500 RENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKIL 1559

Query: 1720 RFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLE 1779
            R +LE  ++K   ++   +++EE+E  +++  + +  L+  L+ E   +   L  K+ +E
Sbjct: 1560 RAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKME 1619

Query: 1780 GLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQ 1839
            G +  +  Q+ H +  +    ++ ++   +LL D Q+ L            ++  + +  
Sbjct: 1620 GDLNEMEIQLSHAN-RMAAEAQKQVKSLQSLLKDTQIQL------------DDAVRANDD 1666

Query: 1840 LEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDED 1899
            L+++ A  E   +   +L A+LE + + +E   R++ L +++L     E+  LL      
Sbjct: 1667 LKENIAIVE---RRNNLLQAELEELRAVVEQTERSRKLAEQELIETS-ERVQLL-----H 1717

Query: 1900 QDDLNELMQKHKDLIAQSAADIGQIQ-ELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQS 1958
              + + + QK K       AD+ Q+Q E++  ++E +  + K ++ +  A M  E L++ 
Sbjct: 1718 SQNTSLINQKKK-----MDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKE 1772

Query: 1959 TVDRAIVSR----QEAVICDLENK-TEFQKVQI----KRFEVLVIRLRDSLIKMGEELSQ 2009
                A + R     E  I DL+++  E +++ +    K+ + L  R+R+   ++  E  +
Sbjct: 1773 QDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKR 1832

Query: 2010 AATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTD 2069
             A S    R+S +  +    + + D + L++ +    +  ++++ Y  +     +   T+
Sbjct: 1833 NAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTN 1892

Query: 2070 LETSIRRIADLQAALEEVASSDSDTESVQT-AVDCGSSGRKE 2110
            L    +   +L  A E    ++S    ++  + D G+ G  E
Sbjct: 1893 LSKFRKVQHELDEAEERADIAESQVNKLRAKSRDIGTKGLNE 1934


>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
          Length = 2003

 Score =  372 bits (954), Expect = e-102
 Identities = 469/1947 (24%), Positives = 831/1947 (42%), Gaps = 249/1947 (12%)

Query: 497  GQSRDSDQAPEDRWYEAEKVWL-AQKDGFTLATVLKPDEGTADLP---AGRVRLWIDADK 552
            G    S  +P+  W     VW+ ++  GF  A +    E  A++    +GR RL +  D+
Sbjct: 37   GGGPGSGTSPQVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGR-RLRLPRDQ 95

Query: 553  TITEVDEEHVHRANPPELDQVEDLASLISVNESSVLNTLLQRYKAQLLHTCTGPDLIVLQ 612
                     + R NPP+  + ED+A L  +NE+SVL+ L +RY + L++T +G   +V+ 
Sbjct: 96   ---------IQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVIN 146

Query: 613  P--RGPSVPSA-GKVPKGR-RDGLPAHIGSMAQRAYWALLNQRRDQSIVALGWSGAGKTT 668
            P  + P    A  ++ +G+ R  +P H+ ++ + AY ++L  R DQSI+  G SGAGKT 
Sbjct: 147  PYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTE 206

Query: 669  CCEQVLEHLVGMAGSVDGR-----------VSVEKIRATFT----VLRAFGSVSMAHSRS 713
              ++V+++L  +A S  GR           VS  ++         +L AFG+     + +
Sbjct: 207  NTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDN 266

Query: 714  ATRFSMVMSLDFNATGRITAAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTE 773
            ++RF   + ++F+  G I  A ++T LLEKSR  RQ + E +F +F Q+L G    L+ +
Sbjct: 267  SSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKAD 326

Query: 774  LNLHQMADSSSFGMGVWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHL 833
            L L   +       G  S P  +++    F +   ++ +LG S  E  ++ R+++A+   
Sbjct: 327  LLLEPCSHYRFLTNGPSSSPGQEREL---FQETLESLRVLGFSHEEIISMLRMVSAVLQF 383

Query: 834  GAAGACKVGRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWGLED 893
            G   A K  R         N AA+ L C    L    F   L  +  ++  G       D
Sbjct: 384  GNI-ALKRERNTDQATMPDNTAAQKL-CRLLGLGVTDFSRAL--LTPRIKVG------RD 433

Query: 894  EETSSGLKMTGVDCVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIM-VVDSPGFQNP 952
                +  K      +E +A   Y+ LF  +V  +NR+        AS + ++D  GF+  
Sbjct: 434  YVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEI- 492

Query: 953  RHQGKDRAATFEELCHNYAHERLQLLFYQRTFVSTLQRYQEEGVP---VQFDLPDPSPGT 1009
                  +  +FE+LC NY +E+LQ LF    FV   + YQ EG+P   + F L D  P  
Sbjct: 493  -----FQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL-DLQPCI 546

Query: 1010 TVAVVDQNPSQVRLPAGGGAQDARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTE 1069
             +     NP               GL  +LDEE     ++D   +E++     ++  G  
Sbjct: 547  DLIERPANPP--------------GLLALLDEECWFPKATDKSFVEKVA----QEQGGHP 588

Query: 1070 GSSALRTCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSL 1129
                 R         + H  G   V Y    WL +    L+  +   +LHQS        
Sbjct: 589  KFQRPRHLRDQADFSVLHYAG--KVDYKANEWLMKNMDPLND-NVAALLHQSTD------ 639

Query: 1130 FQARAKLPPVCRAVAGLEGTSQ--QALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMDAL 1187
             +  A++      + GLE  S         R  R  F         +      K  +  L
Sbjct: 640  -RLTAEIWKDVEGIVGLEQVSSLGDGPPGGRPRRGMF---------RTVGQLYKESLSRL 689

Query: 1188 TSMIKRSRLHFIHCLVPNPVVESRSGQESPPPPQPGRDKPGAGGPLALDIPALRVQLAGF 1247
             + +  +   F+ C+VPN   E R+G+  P               L LD      QL   
Sbjct: 690  MATLSNTNPSFVRCIVPNH--EKRAGKLEPR--------------LVLD------QLRCN 727

Query: 1248 HILEALRLHRTGYADHMGLTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLETLDLE 1307
             +LE +R+ R G+ + +    FR+++++L    + K       +D ++A E++++ L+L+
Sbjct: 728  GVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGF-----MDGKQACEKMIQALELD 782

Query: 1308 KKAVAVGHSQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQ 1367
                 VG S++F +AGV+++LE++R+  V+  IV FQAA +G+L+R+ F+K + ++ A +
Sbjct: 783  PNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALR 842

Query: 1368 CIQKNVAVFLAVKDWPWWQLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEKLRNE 1427
             +Q+N A +L ++ W WW+L   ++PLL  T   E L+A+ +EL  ++   ++S +   E
Sbjct: 843  VMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGE 902

Query: 1428 LRQNTDLLESKIADLTSDLADERFKGDVACQVLESERAERLQAFREVQELKSKHEQVQKK 1487
            L+     LE + A L   L  E       C   E  R  RL A +  QEL+    +++ +
Sbjct: 903  LQGRVAQLEEERARLAEQLRAEA----ELCAEAEETRG-RLAARK--QELELVVSELEAR 955

Query: 1488 LG---DVNKQLEEAQQKIQ--LNDLERN---PTGGADEWQMRFDCAQMENEFLRKRLQQC 1539
            +G   + ++Q++  ++++Q  + +LE +     G   + Q+     + + +   + L   
Sbjct: 956  VGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLL 1015

Query: 1540 EERLDSELTARKELEQKLGEL--QSAYDGAK-KMAHQLKRKCHHLTCDLEDTCVLLENQQ 1596
            E++       RK LE +L E   Q+A +  K K  ++L+ K      D+ED    L  ++
Sbjct: 1016 EDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDR---LRKEE 1072

Query: 1597 SRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEAS 1656
                ELEK +++ D       GES     L+E++ ++         +L+ QL +KE+E  
Sbjct: 1073 KGRQELEKLKRRLD-------GES---SELQEQMVEQQQRAE----ELRAQLGRKEEELQ 1118

Query: 1657 QLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQ 1716
                + E     + +LL S        A L E    LES  + + K + Q+ +  ++LE 
Sbjct: 1119 AALARAEDEGGARAQLLKSL---REAQAALAEAQEDLESERVARTKAEKQRRDLGEELEA 1175

Query: 1717 LRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQ 1776
            LR   E            D  D     +++R   ++ + +L+  LE+E    +  + E +
Sbjct: 1176 LRGELE------------DTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELR 1223

Query: 1777 DLEG-LIGTLCDQI--GHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSKEEL 1833
               G  +G L +Q+    R     ++ R  L    A +S+++  L +++  +    ++  
Sbjct: 1224 QRHGQALGELAEQLEQARRGKGAWEKTRLAL---EAEVSELRAELSSLQTARQE-GEQRR 1279

Query: 1834 EKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLL 1893
             ++  QL++ + +  +  + +      L+   +ELEN++   +  + +  RL  E +   
Sbjct: 1280 RRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTE 1339

Query: 1894 KRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIE 1953
             ++ + Q+ L E  +    L ++  A   +   L+ QLEE    + +   +LQ AQ ++ 
Sbjct: 1340 AQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLS 1399

Query: 1954 -----------YLEQSTVDRAIVSRQ-EAVICDLENKTEFQKVQIKRFEVLVIRLRDSLI 2001
                        LE     R   +R+ EA+   L  KTE      +    L   L D+ +
Sbjct: 1400 EWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATM 1459

Query: 2002 KMGEELSQAATSESQQRESSQYYQRRLEELKADMEELVQREAEA---SRRCMELEKYVEE 2058
             + ++    +T E +QR+  Q        +   +EE  + EAE      R + L + +EE
Sbjct: 1460 DLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEE 1519

Query: 2059 LAAVRQTLQTDLETSIRRIADLQAALEEVASSDSDT-ESVQTAVDCGSSGRKEMDNVSIL 2117
                R+ L+       R+   L+A LE + SS  D  +SV           +  +++   
Sbjct: 1520 EQEAREELE-------RQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQ 1572

Query: 2118 SSQPEGSLQSWLSCTLSLATDTMRTPSRQSATSSRILSPRINEEAGDTERTQSALALSRA 2177
             ++ E  L +     L L      T         R L  R  +EAG+  R Q A      
Sbjct: 1573 VTELEDELTAAEDAKLRLEV----TVQALKTQHERDLQGR--DEAGEERRRQLA------ 1620

Query: 2178 RSTNVHSKTSGDKPVSPHFVRRQKYCHFGDGEVLAVQRKSTERLEPASSPLASRSTNTSP 2237
                   K   D  V     R+Q+         +A ++K    LE   + +AS       
Sbjct: 1621 -------KQLRDAEVERDEERKQRTL------AVAARKKLEGELEELKAQMASAGQGKEE 1667

Query: 2238 LSRE--KLPSPSAALSEFVEGLRRKRAQ------RGQGSTLGLEDWPTLPIYQTTGASTL 2289
              ++  K+ +    L   VE  R  R +        +    GLE    L + +   AS  
Sbjct: 1668 AVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEA-EVLRLQEELAASDR 1726

Query: 2290 RRGRAGSD---------EGNLSLRVGAKSPLEIEGAAGGLLRSTSLKCISSDGVGG---T 2337
             R +A  D          GNLS     +   ++EG  G L      +  +S+ +      
Sbjct: 1727 ARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRK 1786

Query: 2338 TLLPEKSKTQFSSCESLLESRPSMGRK 2364
             LL  +S T   S E    ++   GR+
Sbjct: 1787 LLLQVESLTTELSAERSFSAKAESGRQ 1813



 Score =  147 bits (372), Expect = 1e-34
 Identities = 177/762 (23%), Positives = 330/762 (43%), Gaps = 98/762 (12%)

Query: 1406 AKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESERA 1465
            A E E++ LR +L   +  R E  Q    LE ++ ++     D       A + L+  +A
Sbjct: 1253 ALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQA 1312

Query: 1466 ERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPTGGADEWQMRFDCA 1525
            E       + E +SK  ++ K+L     QL +AQ+ +Q     +   G       R    
Sbjct: 1313 ELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGS------RVRAM 1366

Query: 1526 QMENEFLRKRLQQ---CEERLDSELTA--------RKELEQKLGELQSAYDGAKKMAHQ- 1573
            + E   LR++L++     ER   EL          R+  E++ G L++  +  ++ A + 
Sbjct: 1367 EAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREA 1426

Query: 1574 ----------------LKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQAL 1617
                            L+R    L  +L+D  + LE Q+     LEKKQ+KFD  LA+  
Sbjct: 1427 EALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEK 1486

Query: 1618 GESVFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPS 1677
               +     RE+   E          L + L+++++   +L++Q   L+     LL S  
Sbjct: 1487 AAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKD 1546

Query: 1678 LGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDRE 1737
                 V  L+      E +A + +   ++ E+ +   E  + R E+ ++ +K  H++D +
Sbjct: 1547 DVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQ 1606

Query: 1738 DQEEELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVE 1797
             ++E  E+ R+   K+L   E++ ++E +++ + +  ++ LEG +  L  Q+       E
Sbjct: 1607 GRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKE 1666

Query: 1798 KRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCE----EALKT 1853
            + +++ LR+  A + +   L   +E+ +TS      E++ SQ  +SE + +    E L+ 
Sbjct: 1667 EAVKQ-LRKMQAQMKE---LWREVEETRTS-----REEIFSQNRESEKRLKGLEAEVLRL 1717

Query: 1854 QKVLTA----------DLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDL 1903
            Q+ L A          D + M  E+ N   +K+ + E+  +L+     L + ++E+Q + 
Sbjct: 1718 QEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNS 1777

Query: 1904 NELMQKHKDLIAQSAADIGQIQELQLQLE-----EAKKEKHKLQEQLQVAQMRIEYLEQS 1958
              L  +++ L+ Q       ++ L  +L       AK E  + Q + Q+ ++R    E+ 
Sbjct: 1778 ELLNDRYRKLLLQ-------VESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEED 1830

Query: 1959 TVDRAIVSRQEAVICDLENK---TEFQKVQIKRFEVLV--------IRLRDSLIKMGEEL 2007
               RA   R +  I  LE+K    E Q  Q  R  +L          RL++ ++++ EE 
Sbjct: 1831 AGARA---RHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER 1887

Query: 2008 SQAATSESQQRESSQYYQRRLEELKADMEELVQR--EAEASRRCM--ELEKYVE------ 2057
              A     Q R+  +    R+++LK  +EE  +    A+A RR +  ELE   E      
Sbjct: 1888 RVA----DQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMN 1943

Query: 2058 -ELAAVRQTLQTDLETSIRRIADLQAALEEVASSDSDTESVQ 2098
             E+  +R  L+    T   R       LEE  +SD + E  Q
Sbjct: 1944 REVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQ 1985



 Score = 33.1 bits (74), Expect = 3.6
 Identities = 35/132 (26%), Positives = 54/132 (40%), Gaps = 21/132 (15%)

Query: 357  KTSQVQGELGDDLRMGEKAGELRSTTGKAGESWDKKEKMGQPQGKSGNAGEARSQTEKGC 416
            K +Q + +L  + R    +G+L     K       KE + Q + +   A + R Q EKG 
Sbjct: 1847 KLAQAEEQLEQETRERILSGKLVRRAEKR-----LKEVVLQVEEERRVADQLRDQLEKGN 1901

Query: 417  EAPKEVSTMVESPAAPGKGGWPGSRGQEAEEPCSRAGDGAGALETELEGPSQPALEKDAE 476
               K++   +E                EAEE  SRA  G   L+ ELE  ++ A   + E
Sbjct: 1902 LRVKQLKRQLE----------------EAEEEASRAQAGRRRLQRELEDVTESAESMNRE 1945

Query: 477  RPRIRKENQDGP 488
               +R   + GP
Sbjct: 1946 VTTLRNRLRRGP 1957


>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
            sapiens]
          Length = 1939

 Score =  371 bits (952), Expect = e-102
 Identities = 394/1736 (22%), Positives = 767/1736 (44%), Gaps = 227/1736 (13%)

Query: 503  DQAPEDRWYEAEKVWLAQK--DGFTLATVLKPDEG-----TADLPAGRVRLWIDADKTIT 555
            + AP  R  E E++    K  D  T   V+ P E            G+V    +A  T+T
Sbjct: 12   EAAPFLRKSEKERIEAQNKPFDAKTSVFVVDPKESYVKAIVQSREGGKVTAKTEAGATVT 71

Query: 556  EVDEEHVHRANPPELDQVEDLASLISVNESSVLNTLLQRYKAQLLHTCTGPDLIVLQPR- 614
             V E+ V   NPP+ D++ED+A +  ++E +VL  L +RY A +++T +G   + + P  
Sbjct: 72   -VKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYK 130

Query: 615  -----GPSVPSAGKVPKGRRDGLPAHIGSMAQRAYWALLNQRRDQSIVALGWSGAGKTTC 669
                  P V +A +  K  R   P HI S++  AY  +L  R +QSI+  G SGAGKT  
Sbjct: 131  WLPVYNPEVVTAYRGKK--RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVN 188

Query: 670  CEQVLEHLVGMA------------GSVDGRVSVEKIRATFTVLRAFGSVSMAHSRSATRF 717
             ++V+++   +A            G + G +  + I A   +L AFG+     + +++RF
Sbjct: 189  TKRVIQYFATIAVTGEKKKEEPASGKMQGTLEDQIISAN-PLLEAFGNAKTVRNDNSSRF 247

Query: 718  SMVMSLDFNATGRITAAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTEL--- 774
               + + F ATG++ +A ++T LLEKSRV  Q + E ++ +F Q+L+    +L   L   
Sbjct: 248  GKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPELIEMLLIT 307

Query: 775  -NLHQMADSSSFGMGVWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHL 833
             N +  A  S   + V S  + ++  A        A+++LG +  E+ A++++  A+ H 
Sbjct: 308  TNPYDFAFVSQGEITVPSIDDQEELMAT-----DSAVDILGFTADEKVAIYKLTGAVMHY 362

Query: 834  GAAGACKVGRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWGLED 893
            G      +  KQ  R E     AE  G E  +        +   +++ + +   + G  +
Sbjct: 363  G-----NMKFKQKQREE----QAEPDGTEVADKAAYLTSLNSADLLKSLCYPRVKVG--N 411

Query: 894  EETSSGLKMTGV-DCVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNP 952
            E  + G  +  V + V  +A  +Y+++F  +V+ IN+   +       I V+D  GF+  
Sbjct: 412  EFVTKGQTVQQVYNAVGALAKAIYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIF 471

Query: 953  RHQGKDRAATFEELCHNYAHERLQLLFYQRTFVSTLQRYQEEGVPVQFDLPDPSPGTTVA 1012
                     + E+LC N+ +E+LQ  F    FV   + Y++EG+  +F          + 
Sbjct: 472  DFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIE 525

Query: 1013 VVDQNPSQVRLPAGGGAQDARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTEGSS 1072
            ++++                 G+F +L+EE     ++D+    +L      K    +   
Sbjct: 526  LIEK---------------PMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPK 570

Query: 1073 ALRTCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSLFQA 1132
              +  +      + H  G   V Y++ GWL + K  L+      +  +S  + L  LF  
Sbjct: 571  PAKG-KPEAHFSLVHYAG--TVDYNIAGWLDKNKDPLNET-VVGLYQKSAMKTLAFLFSG 626

Query: 1133 RAKLPPVCRAVAGLEGTSQQALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMDALTSMIK 1192
                        G +G  ++          +F +  A  R           ++ L + ++
Sbjct: 627  AQTAE--AEGGGGKKGGKKKG--------SSFQTVSALFREN---------LNKLMTNLR 667

Query: 1193 RSRLHFIHCLVPNPVVESRSGQESPPPPQPGRDKPGAGGPLALDIPALRVQLAGFHILEA 1252
             +  HF+ C++PN   E+++                   P A++   +  QL    +LE 
Sbjct: 668  STHPHFVRCIIPN---ETKT-------------------PGAMEHELVLHQLRCNGVLEG 705

Query: 1253 LRLHRTGYADHMGLTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLETLDLEKKAVA 1312
            +R+ R G+   +    F+++++VL+A  + +     + ID +KA E+LL +++++     
Sbjct: 706  IRICRKGFPSRILYADFKQRYKVLNASAIPE----GQFIDSKKASEKLLGSIEIDHTQYK 761

Query: 1313 VGHSQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKN 1372
             GH++VF KAG++  LE+ R++ ++Q I   QA C+GFL R EF+K+  RR +  CIQ N
Sbjct: 762  FGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAICRGFLMRVEFRKMMERRESIFCIQYN 821

Query: 1373 VAVFLAVKDWPWWQLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEKLRNELRQNT 1432
            +  F+ VK WPW +L   ++PLL +    +++   +EE    + +L K+E  R EL +  
Sbjct: 822  IRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKM 881

Query: 1433 DLLESKIADL-------------TSDLADERFKGDVACQVLESERAERLQAFREVQ-ELK 1478
              L  +  DL               +  D+  K  +  +    E  ER +   E+  EL 
Sbjct: 882  VTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELT 941

Query: 1479 SKHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPT-----------GGADEWQMRF----D 1523
            +K  +++ +  ++ K +++ +  +   + E++ T            G DE   +      
Sbjct: 942  AKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKK 1001

Query: 1524 CAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTC 1583
              Q  ++     LQ  E+++++   A+ +LEQ++ +L+ + +  KK+   L+R    L  
Sbjct: 1002 ALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEG 1061

Query: 1584 DLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQ 1643
            DL+       + ++   +L +K KK + +++   G+   E+ L  ++ ++   ++  + +
Sbjct: 1062 DLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEE 1121

Query: 1644 LQQQLK-------QKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESS 1696
            L+++++       + E++ S L +++E + +   E  G+ S              ++E +
Sbjct: 1122 LEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSA-------------QIEMN 1168

Query: 1697 ALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQ---KDREDQEEELEDVRQSCQKR 1753
               + + Q  +    + LE+   + E     +++ H     +  +Q + L+ V+Q  +K 
Sbjct: 1169 KKREAEFQKMR----RDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKE 1224

Query: 1754 LHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSD 1813
              +L+M++       + V   K + E +  TL DQ+       E++              
Sbjct: 1225 KSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQ-------------- 1270

Query: 1814 VQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTR 1873
             Q L+  +   K  +  E  E    QL++ +A   +  + ++  T  +E +  +LE  T+
Sbjct: 1271 -QRLINELSAQKARLHTESGE-FSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETK 1328

Query: 1874 NKSLVDEQLYRLQFEKADLLKRIDEDQDDLNEL---MQKHKDLIAQ--SAADIGQIQELQ 1928
             KS +   L   + +   L ++ +E+Q+   EL   M K    +AQ  +  +   IQ  +
Sbjct: 1329 AKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTE 1388

Query: 1929 LQLEEAKKEKHKLQEQLQVAQMRIE--------------YLEQSTVDRAI-VSRQEAVIC 1973
             +LEEAKK   KL ++LQ A+  +E               L+    D  I V R  A   
Sbjct: 1389 -ELEEAKK---KLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACI 1444

Query: 1974 DLENK-TEFQKVQI---KRFEVLVIRLRDSLIK---MGEELSQAATSESQQRESSQYYQR 2026
             L+ K   F KV     +++E     L  S  +   +  EL +   +  +  +  +  +R
Sbjct: 1445 ALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKR 1504

Query: 2027 RLEELKADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEE 2086
              + L+ ++ +L ++ AE  +   ELEK  ++L   +  LQT LE +    A L+    +
Sbjct: 1505 ENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEA---EASLEHEEGK 1561

Query: 2087 VASSDSDTESVQTAVDCGSSGR-KEMDNVSILSSQPEGSLQSWLSCTLSLATDTMR 2141
            +     +   V++ +D   + + +E+D +     +   S+QS L   +    D +R
Sbjct: 1562 ILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALR 1617



 Score =  132 bits (331), Expect = 6e-30
 Identities = 144/704 (20%), Positives = 313/704 (44%), Gaps = 73/704 (10%)

Query: 1387 LLGSLQPLLSATIGTEQL-RAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSD 1445
            L  +++ +  A    E++ R  E++L+ ++ K E+ ++L NEL      L ++  + +  
Sbjct: 1235 LASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQ 1294

Query: 1446 LADERFKGDVACQVLESERAERLQAF-REVQELKSKHEQVQKKLGDVNKQLEEAQQKIQL 1504
            L DE+         + S+ +   QAF ++++ELK + E+  K    +   L+ A+    L
Sbjct: 1295 L-DEK-------DAMVSQLSRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDL 1346

Query: 1505 --NDLERNPTGGADEWQ----MRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLG 1558
                 E      A+  +       + AQ   ++    +Q+ EE  +    A+K+L Q+L 
Sbjct: 1347 LREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEE----AKKKLAQRLQ 1402

Query: 1559 ELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALG 1618
            + +   +        L++    L  ++ED  + +E   +    L+KKQ+ FD  LA+   
Sbjct: 1403 DAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQ 1462

Query: 1619 ESVFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSL 1678
            +    +   E   +E+ S+  EL +++   ++       LK++ + LQ    +L    + 
Sbjct: 1463 KYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAE 1522

Query: 1679 GENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDRED 1738
            G   +  L++   +L+    E Q    + E +++  E    R +LE+ ++K    +   +
Sbjct: 1523 GGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAE 1582

Query: 1739 QEEELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEK 1798
            ++EEL+ ++++  + +  ++  L+ E   +   L  K+ +EG +  +  Q+ H +    +
Sbjct: 1583 KDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAE 1642

Query: 1799 RLRRDLRRTHALLSDVQLLLG-------------TMEDGKTSVSKEELEKVHSQLEQSEA 1845
             L R+LR T  +L D QL L               M + + ++ + E+E++ + LE++E 
Sbjct: 1643 AL-RNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTER 1701

Query: 1846 KCEEA---------------------LKTQKVLTADLESMHSELENMTRNKSLVDEQLYR 1884
              + A                     + T+K L  D+  +  E+E++ +     +E+  +
Sbjct: 1702 GRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKK 1761

Query: 1885 LQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEA--------KK 1936
               + A + + + ++QD    L +  K++          +++LQL+L+EA        KK
Sbjct: 1762 AITDAAMMAEELKKEQDTSAHLERMKKNMEQ-------TVKDLQLRLDEAEQLALKGGKK 1814

Query: 1937 EKHKLQEQLQVAQMRIEYLEQSTVDRAI-VSRQEAVICDLENKTEFQKVQIKRFEVLVIR 1995
            +  KL+ +++  +  +E  ++  V+    + + E  + +L  +TE  +  I R + LV +
Sbjct: 1815 QIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDK 1874

Query: 1996 LRDSLIKMGEELSQAATSESQQRESSQYYQRRLEELK--ADMEE 2037
            L+  +     +  +A    +      +  Q  LEE K  AD+ E
Sbjct: 1875 LQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAE 1918



 Score = 88.6 bits (218), Expect = 7e-17
 Identities = 129/614 (21%), Positives = 258/614 (42%), Gaps = 69/614 (11%)

Query: 1404 LRAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESE 1463
            L++   +   LR + E+ ++ + EL++      S++A   +     +++ D   +  E E
Sbjct: 1337 LQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRT-----KYETDAIQRTEELE 1391

Query: 1464 RAERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQKIQ--LNDLERNPTG--GADEWQ 1519
             A++  A R +Q+ +   E V  K   + K  +  Q +++  + D+ER+       D+ Q
Sbjct: 1392 EAKKKLAQR-LQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQ 1450

Query: 1520 MRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCH 1579
              FD    E    +++ ++ +  L++     + L  +L ++++AY+ +      LKR+  
Sbjct: 1451 RNFDKVLAE---WKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLETLKRENK 1507

Query: 1580 HLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQ-------LAQALGESVFEKGLREKVTQ 1632
            +L  ++ D    +       HELEK +K+ D +       L +A      E+G   ++  
Sbjct: 1508 NLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQL 1567

Query: 1633 ENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWK 1692
            E   V+ E+    +++ +K++E  QLK+    + +  +  L +     N    +K+++  
Sbjct: 1568 ELNQVKSEI---DRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKM-- 1622

Query: 1693 LESSALEQQKIQSQQENTIKQLEQLRQ-RFELEIERMKQMHQKD----REDQEEELEDVR 1747
                 L + +IQ    N  +  E LR  R    I +  Q+H  D    ++D +E+L  V 
Sbjct: 1623 --EGDLNEMEIQLNHANR-QAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVE 1679

Query: 1748 QSC---QKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDL 1804
            +     Q  + +L   LE+    ++M   E  D    +  L  Q      + +K+L  D+
Sbjct: 1680 RRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQ-NTSLINTKKKLETDI 1738

Query: 1805 RRTHALLSD-VQLLLGTMEDGKTSVSKEELEKVHSQLEQ-SEAKCEEALKTQKVLTADLE 1862
             +    + D VQ      E  K +++   +     + EQ + A  E   K  +    DL+
Sbjct: 1739 SQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1798

Query: 1863 SMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNEL---MQKH----KDLIA 1915
                E E +        +Q+ +L+    +L   ++ +Q    E    ++KH    K+L  
Sbjct: 1799 LRLDEAEQLALKGG--KKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTY 1856

Query: 1916 QSAADIGQIQELQ--------------LQLEEAKKEKH-------KLQEQLQVAQMRIEY 1954
            Q+  D   I  LQ               Q EEA+++ +       KLQ +L+ A+ R + 
Sbjct: 1857 QTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADI 1916

Query: 1955 LEQSTVDRAIVSRQ 1968
             E       + SR+
Sbjct: 1917 AESQVNKLRVKSRE 1930



 Score = 77.8 bits (190), Expect = 1e-13
 Identities = 118/576 (20%), Positives = 242/576 (42%), Gaps = 104/576 (18%)

Query: 1359 LKIRRLAAQCI-----QKNVAVFLAVKDWPWWQLLGSLQPLLSATIGTEQLRAKEEELTT 1413
            + + R  A CI     Q+N    LA     W Q     Q  L A+   ++ R+   EL  
Sbjct: 1434 IDVERSNAACIALDKKQRNFDKVLA----EWKQKYEETQAELEAS--QKESRSLSTELFK 1487

Query: 1414 LRRKLEKSEKLRNELRQNTDLLESKIADLTSDLAD--------ERFKGDVACQVLESERA 1465
            ++   E+S      L++    L+ +I+DLT  +A+        E+ K     + L+ E++
Sbjct: 1488 VKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVK-----KQLDHEKS 1542

Query: 1466 ERLQAFREVQELKSKHEQ-----VQKKLGDVNKQLEE--AQQKIQLNDLERNPTGGADEW 1518
            E LQ   E  E   +HE+     +Q +L  V  +++   A++  +L+ L+RN     +  
Sbjct: 1543 E-LQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESM 1601

Query: 1519 QMRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKC 1578
            Q   D        +R R        +  L  +K++E  L E++   + A + A +  R  
Sbjct: 1602 QSTLDAE------IRSR--------NDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNL 1647

Query: 1579 HHLTCDLEDTCVLLEN----QQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQEN 1634
             +    L+DT + L++    Q     +L   +++ +L  A+                   
Sbjct: 1648 RNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEV------------------ 1689

Query: 1635 TSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLE 1694
              +R  L + ++  K  EQE     ++V++L      L+ +                KLE
Sbjct: 1690 EELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKK--------------KLE 1735

Query: 1695 SSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQ--KDREDQEEELEDVRQSCQK 1752
            +      +IQ + E+ +++     ++ +  I     M +  K  +D    LE ++++ ++
Sbjct: 1736 TDI---SQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQ 1792

Query: 1753 RLHQLEMQLEQEYEEKQMVLH----EKQDLEGLIGTLCDQI-GHRDFDVE--KRLRRDLR 1805
             +  L+++L+   E +Q+ L     + Q LE  +  L  ++   +  +VE  K LR+  R
Sbjct: 1793 TVKDLQLRLD---EAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHER 1849

Query: 1806 RTHALLSDVQLLLGTMEDGKTSVSKEEL-EKVHSQLEQSEAKCEEALKTQKVLTADLESM 1864
            R        +L   T ED K  +  ++L +K+ ++++  + + EEA +   V  A    +
Sbjct: 1850 RVK------ELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFRKL 1903

Query: 1865 HSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQ 1900
              ELE       + + Q+ +L+ +  ++  ++  ++
Sbjct: 1904 QHELEEAKERADIAESQVNKLRVKSREVHTKVISEE 1939


>gi|156104908 myosin heavy chain 6 [Homo sapiens]
          Length = 1939

 Score =  370 bits (951), Expect = e-102
 Identities = 388/1692 (22%), Positives = 756/1692 (44%), Gaps = 222/1692 (13%)

Query: 521  KDGFTLATVLKPDEGTADLPAGRVRLWIDADKTITEVDEEHVHRANPPELDQVEDLASLI 580
            K+ F  A +L  +        G+V    +  KT+T V E+ V + NPP+ D++ED+A L 
Sbjct: 43   KEEFVKAKILSRE-------GGKVIAETENGKTVT-VKEDQVLQQNPPKFDKIEDMAMLT 94

Query: 581  SVNESSVLNTLLQRYKAQLLHTCTGPDLIVLQP-RGPSVPSAGKVPKGR---RDGLPAHI 636
             ++E +VL  L +RY A +++T +G   + + P +   V +A  V   R   R   P HI
Sbjct: 95   FLHEPAVLFNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHI 154

Query: 637  GSMAQRAYWALLNQRRDQSIVALGWSGAGKTTCCEQVLEHLVGMAGSVD----------- 685
             S++  AY  +L  R +QSI+  G SGAGKT   ++V+++   +A   D           
Sbjct: 155  FSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNANANK 214

Query: 686  GRVSVEKIRATFTVLRAFGSVSMAHSRSATRFSMVMSLDFNATGRITAAQLQTMLLEKSR 745
            G +  + I+A    L AFG+     + +++RF   + + F ATG++ +A ++T LLEKSR
Sbjct: 215  GTLEDQIIQAN-PALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSR 273

Query: 746  VARQPEGESNFLVFSQMLAG-----LDLDLRTELNLHQMADSSSFGMGVWSKPEDKQKAA 800
            V  Q + E N+ +F Q+L+      LD+ L T  N +  A  S   + V S  + ++  A
Sbjct: 274  VIFQLKAERNYHIFYQILSNKKPELLDMLLVTN-NPYDYAFVSQGEVSVASIDDSEELMA 332

Query: 801  AAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAAGACKVGRKQFMRFEWANYAAEALG 860
                    A ++LG +  E+  V+++  AI H G      +  KQ  R E     AE  G
Sbjct: 333  T-----DSAFDVLGFTSEEKAGVYKLTGAIMHYG-----NMKFKQKQREE----QAEPDG 378

Query: 861  CEYEELNTATFKHHLRQIIQQMTFGPSRWGLEDEETSSGLKMTGVD-CVEGMASGLYQEL 919
             E  + +      +   +++ +     + G  +E  + G  +  V   +  +A  +Y+++
Sbjct: 379  TEDADKSAYLMGLNSADLLKGLCHPRVKVG--NEYVTKGQSVQQVYYSIGALAKAVYEKM 436

Query: 920  FAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQGKDRAATFEELCHNYAHERLQLLF 979
            F  +V+ IN +  +       I V+D  GF+           +FE+LC N+ +E+LQ  F
Sbjct: 437  FNWMVTRINATLETKQPRQYFIGVLDIAGFEIFDFN------SFEQLCINFTNEKLQQFF 490

Query: 980  YQRTFVSTLQRYQEEGVPVQFDLPDPSPGTTVAVVDQNPSQVRLPAGGGAQDARGLFWVL 1039
                FV   + Y++EG+   F          + ++++                 G+  +L
Sbjct: 491  NHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEK---------------PMGIMSIL 535

Query: 1040 DEEVHVEGSSDSVVLERLCAAFEKKGAGTEGSSALRTCEQPLQCEIFHQLGWDPVRYDLT 1099
            +EE     ++D     +L      K    +    ++  +Q     + H  G   V Y++ 
Sbjct: 536  EEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRNIKG-KQEAHFSLIHYAG--TVDYNIL 592

Query: 1100 GWLHRAKPNLSALDAPQVLHQSKREELRSLFQARAKLPPVCRAVAGLEGTSQQALQRSRM 1159
            GWL + K  L+      +  +S  + + +LF + A       A  G  G S+   ++   
Sbjct: 593  GWLEKNKDPLNET-VVALYQKSSLKLMATLFSSYAT------ADTGDSGKSKGGKKKGSS 645

Query: 1160 VRRTFASSLAAVRRKAPCSQIKLQMDALTSMIKRSRLHFIHCLVPNPVVESRSGQESPPP 1219
             +     +++A+ R+         ++ L + ++ +  HF+ C++PN              
Sbjct: 646  FQ-----TVSALHRE--------NLNKLMTNLRTTHPHFVRCIIPNE------------- 679

Query: 1220 PQPGRDKPGAGGPLALDIPALRVQLAGFHILEALRLHRTGYADHMGLTRFRRQFQVLDAP 1279
                R  PG      +D P +  QL    +LE +R+ R G+ + +    FR+++++L+  
Sbjct: 680  ----RKAPGV-----MDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPV 730

Query: 1280 LLKKLMSTSEGIDERKAVEELLETLDLEKKAVAVGHSQVFLKAGVISRLEKQREKLVSQS 1339
             + +     + ID RK  E+LL +LD++      GH++VF KAG++  LE+ R++ +S+ 
Sbjct: 731  AIPE----GQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRI 786

Query: 1340 IVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKNVAVFLAVKDWPWWQLLGSLQPLLSATI 1399
            I   QA  +G L R EFKK+  RR A   IQ N+  F+ VK+WPW +L   ++PLL +  
Sbjct: 787  ITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAE 846

Query: 1400 GTEQLRAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADL-------------TSDL 1446
              +++   +EE   ++  LEKSE  R EL +    L  +  DL               + 
Sbjct: 847  TEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEER 906

Query: 1447 ADERFKGDVACQVLESERAERLQAFREVQ-ELKSKHEQVQKKLGDVNKQLEEAQQKIQLN 1505
             D+  K  +  +    E  ERL+   E+  EL +K  +++ +  ++ K +++ +  +   
Sbjct: 907  CDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKV 966

Query: 1506 DLERNPT-----------GGADEWQMRF----DCAQMENEFLRKRLQQCEERLDSELTAR 1550
            + E++ T            G DE   +        Q  ++     LQ  E++++S   ++
Sbjct: 967  EKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEEDKVNSLSKSK 1026

Query: 1551 KELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFD 1610
             +LEQ++ +L+ + +  KK+   L+R    L  DL+ T   + + ++   +LE+K KK +
Sbjct: 1027 VKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKE 1086

Query: 1611 LQLAQALGESVFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKR 1670
              + Q             K+  E         QLQ++LK+ +    +L++++E  +  + 
Sbjct: 1087 FDINQQ----------NSKIEDEQVLAL----QLQKKLKENQARIEELEEELEAERTARA 1132

Query: 1671 ELLGSPSLGENCVAGLKERLWKLESSALEQ----QKIQSQQENTIKQLEQLRQRFELEIE 1726
            ++    S     +  + ERL +   +   Q    +K +++ +   + LE+   + E    
Sbjct: 1133 KVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1192

Query: 1727 RMKQMHQ---KDREDQEEELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIG 1783
             +++ H     +  +Q + L+ V+Q  +K   + +++L+      + ++  K +LE +  
Sbjct: 1193 ALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSR 1252

Query: 1784 TLCDQIGH------------RDFDVEK-RLRRDLRRTHALLSDVQLLLGTMEDGKTSVSK 1830
            TL DQ                DF  ++ +L+ +       L + + L+  +  GK S + 
Sbjct: 1253 TLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYT- 1311

Query: 1831 EELEKVHSQLEQSEAKCEEAL-KTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEK 1889
            +++E +  QLE+ E K + AL    +    D + +  + E  T  K+ +   L +   E 
Sbjct: 1312 QQMEDLKRQLEE-EGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEV 1370

Query: 1890 ADLLKRIDEDQDDLNELMQKHKDLIAQSAADIGQ-IQELQLQLEEAKKEKHKLQEQLQVA 1948
            A    + + D     E +++ K  +AQ   D  + ++ +  +    +K KH+LQ +++  
Sbjct: 1371 AQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDL 1430

Query: 1949 QMRIEYLEQSTVDRAIVSRQ---EAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGE 2005
             + +E    +    A+  +Q   + ++ + + K E  + +++  +     L   L K+  
Sbjct: 1431 MVDVE--RSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKL-- 1486

Query: 2006 ELSQAATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKYVEELAAVRQT 2065
                   +  +  E  + ++R  + L+ ++ +L ++  E  +   ELEK  ++L   +  
Sbjct: 1487 -----KNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLE 1541

Query: 2066 LQTDLETSIRRIAD-----LQAALE----------EVASSDSDTE-----------SVQT 2099
            LQ+ LE +   +       L+A LE          ++A  D + E           S+QT
Sbjct: 1542 LQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQT 1601

Query: 2100 AVDCGSSGRKEM 2111
            ++D  +  R E+
Sbjct: 1602 SLDAETRSRNEV 1613



 Score =  130 bits (326), Expect = 2e-29
 Identities = 152/739 (20%), Positives = 322/739 (43%), Gaps = 79/739 (10%)

Query: 1409 EELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLAD-ERFKGDVACQVLESERAER 1467
            E++  L+R  +K EK ++E +   D + S +  +    A+ E+    +  Q  E  R + 
Sbjct: 1207 EQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEY-RVKL 1265

Query: 1468 LQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQKI------------QLNDLERN--PTG 1513
             +A R + +  ++  ++Q + G++ +QLEE +  I            Q+ DL+R     G
Sbjct: 1266 EEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEG 1325

Query: 1514 GADE------WQMRFDCAQMENEF-----LRKRLQQCEERLDSELT-------------- 1548
             A           R DC  +  ++      +  LQ+   + +SE+               
Sbjct: 1326 KAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRT 1385

Query: 1549 -----ARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELE 1603
                 A+K+L Q+L + + A +        L++  H L  ++ED  V +E   +    L+
Sbjct: 1386 EELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALD 1445

Query: 1604 KKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVE 1663
            KKQ+ FD  LA+   +    +   E   +E  S+  EL +L+   ++  +     K++ +
Sbjct: 1446 KKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENK 1505

Query: 1664 MLQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQRFEL 1723
             LQ+   +L      G   V  L++   +LE   LE Q    + E +++  E    R +L
Sbjct: 1506 NLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQL 1565

Query: 1724 EIERMKQMHQKDREDQEEELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIG 1783
            E  ++K   ++   +++EE+E  +++ Q+ +  L+  L+ E   +  VL  K+ +EG + 
Sbjct: 1566 EFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLN 1625

Query: 1784 TLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQS 1843
             +  Q+ H +  +    ++ ++   +LL D Q+ L            ++  + +  L+++
Sbjct: 1626 EMEIQLSHAN-RMAAEAQKQVKSLQSLLKDTQIQL------------DDAVRANDDLKEN 1672

Query: 1844 EAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDL 1903
             A  E   +   +L A+LE + + +E   R++ L +++L     E+  LL        + 
Sbjct: 1673 IAIVE---RRNNLLQAELEELRAVVEQTERSRKLAEQELIETS-ERVQLL-----HSQNT 1723

Query: 1904 NELMQKHKDLIAQSAADIGQIQ-ELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDR 1962
            + + QK K       +D+ Q+Q E++  ++E +  + K ++ +  A M  E L++     
Sbjct: 1724 SLINQKKK-----MESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTS 1778

Query: 1963 AIVSR----QEAVICDLENK-TEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQ 2017
            A + R     E  I DL+++  E +++ +K  +  + +L   + ++  EL       ++ 
Sbjct: 1779 AHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAES 1838

Query: 2018 RESSQYYQRRLEELKADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRI 2077
             +  +  +RR++EL    EE  +          +L+  V+      +  +    T++ + 
Sbjct: 1839 VKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKF 1898

Query: 2078 ADLQAALEEVASSDSDTES 2096
              +Q  L+E        ES
Sbjct: 1899 RKVQHELDEAEERADIAES 1917



 Score = 74.7 bits (182), Expect = 1e-12
 Identities = 105/511 (20%), Positives = 212/511 (41%), Gaps = 75/511 (14%)

Query: 1402 EQLRAKEEELTTLRRKLEKS-EKLRNELRQNTDLLESKIADLTSDLAD---ERFKGDVAC 1457
            ++ R+   EL  L+   E+S E L    R+N +L E +I+DLT  L +      + +   
Sbjct: 1474 KEARSLSTELFKLKNAYEESLEHLETFKRENKNLQE-EISDLTEQLGEGGKNVHELEKVR 1532

Query: 1458 QVLESERAERLQAFREVQELKSKHEQ-----VQKKLGDVNKQLEE--AQQKIQLNDLERN 1510
            + LE E+ E LQ+  E  E   +HE+      Q +   +  ++E   A++  ++   +RN
Sbjct: 1533 KQLEVEKLE-LQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRN 1591

Query: 1511 PTGGADEWQMRFDC-AQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKK 1569
                 D  Q   D   +  NE LR                +K++E  L E++     A +
Sbjct: 1592 HQRVVDSLQTSLDAETRSRNEVLR---------------VKKKMEGDLNEMEIQLSHANR 1636

Query: 1570 MAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREK 1629
            MA + +++   L   L+DT + L++    N +L+               E++     R  
Sbjct: 1637 MAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLK---------------ENIAIVERRNN 1681

Query: 1630 VTQ-ENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKE 1688
            + Q E   +R  + Q ++  K  EQE  +  ++V++L      L+      E+ +  L+ 
Sbjct: 1682 LLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQS 1741

Query: 1689 RLWKLESSALEQQKIQSQQENTIKQLEQLRQRFELE------IERMKQMHQKDREDQEEE 1742
               ++E +  E +  + + +  I     + +  + E      +ERMK+  ++  +D +  
Sbjct: 1742 ---EVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHR 1798

Query: 1743 LEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRR 1802
            L++  Q   K   +   +LE    E +  L  +Q               R+ +  K +R+
Sbjct: 1799 LDEAEQIALKGGKKQLQKLEARVRELEGELEAEQK--------------RNAESVKGMRK 1844

Query: 1803 DLRRTHALLSDVQLLLGTMEDGKTSVSKEEL-EKVHSQLEQSEAKCEEALKTQKVLTADL 1861
              RR        +L   T ED K  +  ++L +K+  +++  + + EEA +      +  
Sbjct: 1845 SERRIK------ELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKF 1898

Query: 1862 ESMHSELENMTRNKSLVDEQLYRLQFEKADL 1892
              +  EL+       + + Q+ +L+ +  D+
Sbjct: 1899 RKVQHELDEAEERADIAESQVNKLRAKSRDI 1929


>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
          Length = 2036

 Score =  369 bits (946), Expect = e-101
 Identities = 471/1973 (23%), Positives = 834/1973 (42%), Gaps = 268/1973 (13%)

Query: 497  GQSRDSDQAPEDRWYEAEKVWL-AQKDGFTLATVLKPDEGTADLP---AGRVRLWIDADK 552
            G    S  +P+  W     VW+ ++  GF  A +    E  A++    +GR RL +  D+
Sbjct: 37   GGGPGSGTSPQVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGR-RLRLPRDQ 95

Query: 553  TITEVDEEHVHRANPPELDQVEDLASLISVNESSVLNTLLQRYKAQLLHTCTGPDLIVLQ 612
                     + R NPP+  + ED+A L  +NE+SVL+ L +RY + L++T +G   +V+ 
Sbjct: 96   ---------IQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVIN 146

Query: 613  P--RGPSVPSA-GKVPKGR-RDGLPAHIGSMAQRAYWALLNQRRDQSIVALGWSGAGKTT 668
            P  + P    A  ++ +G+ R  +P H+ ++ + AY ++L  R DQSI+  G SGAGKT 
Sbjct: 147  PYKQLPIYTEAIVEMYRGKKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTE 206

Query: 669  CCEQVLEHLVGMAGSVDGR-----------VSVEKIRATFT----VLRAFGSVSMAHSRS 713
              ++V+++L  +A S  GR           VS  ++         +L AFG+     + +
Sbjct: 207  NTKKVIQYLAHVASSPKGRKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDN 266

Query: 714  ATRFSMVMSLDFNATGRITAAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTE 773
            ++RF   + ++F+  G I  A ++T LLEKSR  RQ + E +F +F Q+L G    L+ +
Sbjct: 267  SSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKAD 326

Query: 774  LNLHQMADSSSFGMGVWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHL 833
            L L   +       G  S P  +++    F +   ++ +LG S  E  ++ R+++A+   
Sbjct: 327  LLLEPCSHYRFLTNGPSSSPGQEREL---FQETLESLRVLGFSHEEIISMLRMVSAVLQF 383

Query: 834  GAAGACKVGRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWGLED 893
            G   A K  R         N AA+ L C    L    F   L  +  ++  G       D
Sbjct: 384  GNI-ALKRERNTDQATMPDNTAAQKL-CRLLGLGVTDFSRAL--LTPRIKVG------RD 433

Query: 894  EETSSGLKMTGVDCVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIM-VVDSPGFQNP 952
                +  K      +E +A   Y+ LF  +V  +NR+        AS + ++D  GF+  
Sbjct: 434  YVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEI- 492

Query: 953  RHQGKDRAATFEELCHNYAHERLQLLFYQRTFVSTLQRYQEEGVP---VQFDLPDPSPGT 1009
                  +  +FE+LC NY +E+LQ LF    FV   + YQ EG+P   + F L D  P  
Sbjct: 493  -----FQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGL-DLQPCI 546

Query: 1010 TVAVVDQNPSQVRLPAGGGAQDARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTE 1069
             +     NP               GL  +LDEE     ++D   +E++     ++  G  
Sbjct: 547  DLIERPANPP--------------GLLALLDEECWFPKATDKSFVEKVA----QEQGGHP 588

Query: 1070 GSSALRTCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSL 1129
                 R         + H  G   V Y    WL +    L+  +   +LHQS       +
Sbjct: 589  KFQRPRHLRDQADFSVLHYAG--KVDYKANEWLMKNMDPLND-NVAALLHQSTDRLTAEI 645

Query: 1130 FQ--------------------------ARAKLPPVCRAVAGLEGTSQ--QALQRSRMVR 1161
            ++                          + A  PP    + GLE  S         R  R
Sbjct: 646  WKDEHGGFQQFSFLGSFPPSPPGSAERCSSAISPPGVEGIVGLEQVSSLGDGPPGGRPRR 705

Query: 1162 RTFASSLAAVRRKAPCSQIKLQMDALTSMIKRSRLHFIHCLVPNPVVESRSGQESPPPPQ 1221
              F         +      K  +  L + +  +   F+ C+VPN   E R+G+  P    
Sbjct: 706  GMF---------RTVGQLYKESLSRLMATLSNTNPSFVRCIVPNH--EKRAGKLEPR--- 751

Query: 1222 PGRDKPGAGGPLALDIPALRVQLAGFHILEALRLHRTGYADHMGLTRFRRQFQVLDAPLL 1281
                       L LD      QL    +LE +R+ R G+ + +    FR+++++L    +
Sbjct: 752  -----------LVLD------QLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAI 794

Query: 1282 KKLMSTSEGIDERKAVEELLETLDLEKKAVAVGHSQVFLKAGVISRLEKQREKLVSQSIV 1341
             K       +D ++A E++++ L+L+     VG S++F +AGV+++LE++R+  V+  IV
Sbjct: 795  PKGF-----MDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIV 849

Query: 1342 LFQAACKGFLSRQEFKKLKIRRLAAQCIQKNVAVFLAVKDWPWWQLLGSLQPLLSATIGT 1401
             FQAA +G+L+R+ F+K + ++ A + +Q+N A +L ++ W WW+L   ++PLL  T   
Sbjct: 850  SFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQD 909

Query: 1402 EQLRAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLE 1461
            E L+A+ +EL  ++   ++S +   EL+     LE + A L   L  E       C   E
Sbjct: 910  EVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEA----ELCAEAE 965

Query: 1462 SERAERLQAFREVQELKSKHEQVQKKLG---DVNKQLEEAQQKIQ--LNDLERN---PTG 1513
              R  RL A +  QEL+    +++ ++G   + ++Q++  ++++Q  + +LE +     G
Sbjct: 966  ETRG-RLAARK--QELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEG 1022

Query: 1514 GADEWQMRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGEL--QSAYDGAK-KM 1570
               + Q+     + + +   + L   E++       RK LE +L E   Q+A +  K K 
Sbjct: 1023 ARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKS 1082

Query: 1571 AHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKV 1630
             ++L+ K      D+ED    L  ++    ELEK +++ D       GES     L+E++
Sbjct: 1083 LNKLRLKYEATIADMEDR---LRKEEKGRQELEKLKRRLD-------GES---SELQEQM 1129

Query: 1631 TQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERL 1690
             ++         +L+ QL +KE+E      + E     + +LL S        A L E  
Sbjct: 1130 VEQQQRAE----ELRAQLGRKEEELQAALARAEDEGGARAQLLKSL---REAQAALAEAQ 1182

Query: 1691 WKLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSC 1750
              LES  + + K + Q+ +  ++LE LR   E            D  D     +++R   
Sbjct: 1183 EDLESERVARTKAEKQRRDLGEELEALRGELE------------DTLDSTNAQQELRSKR 1230

Query: 1751 QKRLHQLEMQLEQEYEEKQMVLHEKQDLEG-LIGTLCDQI--GHRDFDVEKRLRRDLRRT 1807
            ++ + +L+  LE+E    +  + E +   G  +G L +Q+    R     ++ R  L   
Sbjct: 1231 EQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLAL--- 1287

Query: 1808 HALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSE 1867
             A +S+++  L +++  +    ++   ++  QL++ + +  +  + +      L+   +E
Sbjct: 1288 EAEVSELRAELSSLQTARQE-GEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAE 1346

Query: 1868 LENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADIGQIQEL 1927
            LEN++   +  + +  RL  E +    ++ + Q+ L E  +    L ++  A   +   L
Sbjct: 1347 LENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGL 1406

Query: 1928 QLQLEEAKKEKHKLQEQLQVAQMRIE-----------YLEQSTVDRAIVSRQ-EAVICDL 1975
            + QLEE    + +   +LQ AQ ++             LE     R   +R+ EA+   L
Sbjct: 1407 REQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRL 1466

Query: 1976 ENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQYYQRRLEELKADM 2035
              KTE      +    L   L D+ + + ++    +T E +QR+  Q        +   +
Sbjct: 1467 AEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAV 1526

Query: 2036 EELVQREAEA---SRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSDS 2092
            EE  + EAE      R + L + +EE    R+ L+       R+   L+A LE + SS  
Sbjct: 1527 EERERAEAEGREREARALSLTRALEEEQEAREELE-------RQNRALRAELEALLSSKD 1579

Query: 2093 DT-ESVQTAVDCGSSGRKEMDNVSILSSQPEGSLQSWLSCTLSLATDTMRTPSRQSATSS 2151
            D  +SV           +  +++    ++ E  L +     L L      T         
Sbjct: 1580 DVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEV----TVQALKTQHE 1635

Query: 2152 RILSPRINEEAGDTERTQSALALSRARSTNVHSKTSGDKPVSPHFVRRQKYCHFGDGEVL 2211
            R L  R  +EAG+  R Q A             K   D  V     R+Q+         +
Sbjct: 1636 RDLQGR--DEAGEERRRQLA-------------KQLRDAEVERDEERKQRTL------AV 1674

Query: 2212 AVQRKSTERLEPASSPLASRSTNTSPLSRE--KLPSPSAALSEFVEGLRRKRAQ------ 2263
            A ++K    LE   + +AS         ++  K+ +    L   VE  R  R +      
Sbjct: 1675 AARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNR 1734

Query: 2264 RGQGSTLGLEDWPTLPIYQTTGASTLRRGRAGSD---------EGNLSLRVGAKSPLEIE 2314
              +    GLE    L + +   AS   R +A  D          GNLS     +   ++E
Sbjct: 1735 ESEKRLKGLEA-EVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLE 1793

Query: 2315 GAAGGLLRSTSLKCISSDGVGG---TTLLPEKSKTQFSSCESLLESRPSMGRK 2364
            G  G L      +  +S+ +       LL  +S T   S E    ++   GR+
Sbjct: 1794 GRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQ 1846



 Score =  147 bits (372), Expect = 1e-34
 Identities = 177/762 (23%), Positives = 330/762 (43%), Gaps = 98/762 (12%)

Query: 1406 AKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESERA 1465
            A E E++ LR +L   +  R E  Q    LE ++ ++     D       A + L+  +A
Sbjct: 1286 ALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQA 1345

Query: 1466 ERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPTGGADEWQMRFDCA 1525
            E       + E +SK  ++ K+L     QL +AQ+ +Q     +   G       R    
Sbjct: 1346 ELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGS------RVRAM 1399

Query: 1526 QMENEFLRKRLQQ---CEERLDSELTA--------RKELEQKLGELQSAYDGAKKMAHQ- 1573
            + E   LR++L++     ER   EL          R+  E++ G L++  +  ++ A + 
Sbjct: 1400 EAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREA 1459

Query: 1574 ----------------LKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQAL 1617
                            L+R    L  +L+D  + LE Q+     LEKKQ+KFD  LA+  
Sbjct: 1460 EALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEK 1519

Query: 1618 GESVFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPS 1677
               +     RE+   E          L + L+++++   +L++Q   L+     LL S  
Sbjct: 1520 AAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKD 1579

Query: 1678 LGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDRE 1737
                 V  L+      E +A + +   ++ E+ +   E  + R E+ ++ +K  H++D +
Sbjct: 1580 DVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQ 1639

Query: 1738 DQEEELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVE 1797
             ++E  E+ R+   K+L   E++ ++E +++ + +  ++ LEG +  L  Q+       E
Sbjct: 1640 GRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKE 1699

Query: 1798 KRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCE----EALKT 1853
            + +++ LR+  A + +   L   +E+ +TS      E++ SQ  +SE + +    E L+ 
Sbjct: 1700 EAVKQ-LRKMQAQMKE---LWREVEETRTS-----REEIFSQNRESEKRLKGLEAEVLRL 1750

Query: 1854 QKVLTA----------DLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDL 1903
            Q+ L A          D + M  E+ N   +K+ + E+  +L+     L + ++E+Q + 
Sbjct: 1751 QEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNS 1810

Query: 1904 NELMQKHKDLIAQSAADIGQIQELQLQLE-----EAKKEKHKLQEQLQVAQMRIEYLEQS 1958
              L  +++ L+ Q       ++ L  +L       AK E  + Q + Q+ ++R    E+ 
Sbjct: 1811 ELLNDRYRKLLLQ-------VESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEED 1863

Query: 1959 TVDRAIVSRQEAVICDLENK---TEFQKVQIKRFEVLV--------IRLRDSLIKMGEEL 2007
               RA   R +  I  LE+K    E Q  Q  R  +L          RL++ ++++ EE 
Sbjct: 1864 AGARA---RHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEER 1920

Query: 2008 SQAATSESQQRESSQYYQRRLEELKADMEELVQR--EAEASRRCM--ELEKYVE------ 2057
              A     Q R+  +    R+++LK  +EE  +    A+A RR +  ELE   E      
Sbjct: 1921 RVA----DQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMN 1976

Query: 2058 -ELAAVRQTLQTDLETSIRRIADLQAALEEVASSDSDTESVQ 2098
             E+  +R  L+    T   R       LEE  +SD + E  Q
Sbjct: 1977 REVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEAEEAQ 2018



 Score = 33.1 bits (74), Expect = 3.6
 Identities = 35/132 (26%), Positives = 54/132 (40%), Gaps = 21/132 (15%)

Query: 357  KTSQVQGELGDDLRMGEKAGELRSTTGKAGESWDKKEKMGQPQGKSGNAGEARSQTEKGC 416
            K +Q + +L  + R    +G+L     K       KE + Q + +   A + R Q EKG 
Sbjct: 1880 KLAQAEEQLEQETRERILSGKLVRRAEKR-----LKEVVLQVEEERRVADQLRDQLEKGN 1934

Query: 417  EAPKEVSTMVESPAAPGKGGWPGSRGQEAEEPCSRAGDGAGALETELEGPSQPALEKDAE 476
               K++   +E                EAEE  SRA  G   L+ ELE  ++ A   + E
Sbjct: 1935 LRVKQLKRQLE----------------EAEEEASRAQAGRRRLQRELEDVTESAESMNRE 1978

Query: 477  RPRIRKENQDGP 488
               +R   + GP
Sbjct: 1979 VTTLRNRLRRGP 1990


>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score =  368 bits (945), Expect = e-101
 Identities = 397/1685 (23%), Positives = 741/1685 (43%), Gaps = 244/1685 (14%)

Query: 514  EKVWLAQKDGFTLATVLK--PDEGTADLPAGRVRLWIDADKTITEVDEEHVHRANPPELD 571
            +K W+   +   +   +K   D+GT  +          AD     + E+ + + NPPE +
Sbjct: 52   KKCWIPDGENAYIEAEVKGSEDDGTVIVET--------ADGESLSIKEDKIQQMNPPEFE 103

Query: 572  QVEDLASLISVNESSVLNTLLQRYKAQLLHTCTGPDLIVLQPRG------PSVPSAGKVP 625
             +ED+A L  +NE+SVL+TL +RY   +++T +G   + + P          V +A K  
Sbjct: 104  MIEDMAMLTHLNEASVLHTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGK 163

Query: 626  KGRRDGLPAHIGSMAQRAYWALLNQRRDQSIVALGWSGAGKTTCCEQVLEHLVGMAGSVD 685
              RR   P HI ++A  A+  +L+ R +QSI+  G SGAGKT   + ++++   +A  ++
Sbjct: 164  --RRSEAPPHIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIE 221

Query: 686  GRVSV----EKIRATFTVLRAFGSVSMAHSRSATRFSMVMSLDFNATGRITAAQLQTMLL 741
             R       ++I    T+L AFG+     + +++RF   + + F A G +++  +   LL
Sbjct: 222  SRKKQGALEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLL 281

Query: 742  EKSRVARQPEGESNFLVFSQMLAGLDLDLRTELNLHQM----ADSSSF-----GMGVWSK 792
            EKSRV  Q  GE N+ +F Q+L+G       +  LH +    A+ S F     G      
Sbjct: 282  EKSRVIFQQAGERNYHIFYQILSG-------QKELHDLLLVSANPSDFHFCSCGAVTVES 334

Query: 793  PEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAAGACKVGRKQFMRF--- 849
             +D ++  A     + AM++LG    E+   +++  AI H G     +  R++ +     
Sbjct: 335  LDDAEELLAT----EQAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREEQLEADGT 390

Query: 850  EWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWGLEDEETSSGLKMTGVDCVE 909
            E A+ AA  +G    EL        ++              + +E  + G  +  V C  
Sbjct: 391  ENADKAAFLMGINSSELVKCLIHPRIK--------------VGNEYVTRGQTIEQVTCAV 436

Query: 910  G-MASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQGKDRAATFEELCH 968
            G ++  +Y+ +F  +V+ INR+  +       I ++D  GF+   +       + E+LC 
Sbjct: 437  GALSKSMYERMFKWLVARINRALDAKLSRQFFIGILDITGFEILEYN------SLEQLCI 490

Query: 969  NYAHERLQLLFYQRTFVSTLQRYQEEG---VPVQFDLPDPSPGTTVAVVDQNPSQVRLPA 1025
            N+ +E+LQ  F    FV   + Y++E    V + F L         A +D          
Sbjct: 491  NFTNEKLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLD------LQACIDL--------- 535

Query: 1026 GGGAQDARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTEGSSALRTCEQPLQCEI 1085
                +   G+  +L+EE     ++D     +L      K    +     +  +     E+
Sbjct: 536  ---IEKPMGILSILEEECMFPKATDLTFKTKLFDNHFGKSVHLQKPKPDKK-KFEAHFEL 591

Query: 1086 FHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSLFQARAKLPPVCRAVAG 1145
             H  G  P  Y+++GWL + K  L+      V  +S    L SLF+              
Sbjct: 592  VHYAGVVP--YNISGWLEKNKDLLNET-VVAVFQKSSNRLLASLFENYM----------- 637

Query: 1146 LEGTSQQALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMDALTSMIKRSRLHFIHCLVPN 1205
               ++  A+      R+  AS       +   S  K  ++ L + +K +  HF+ C+ PN
Sbjct: 638  ---STDSAIPFGEKKRKKGASF------QTVASLHKENLNKLMTNLKSTAPHFVRCINPN 688

Query: 1206 PVVESRSGQESPPPPQPGRDKPGAGGPLALDIPALRVQLAGFHILEALRLHRTGYADHMG 1265
                                 PG      LD   +  QL    +LE  R+ R G+ + + 
Sbjct: 689  V-----------------NKIPGI-----LDPYLVLQQLRCNGVLEGTRICREGFPNRLQ 726

Query: 1266 LTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLETLDLEKKAVAVGHSQVFLKAGVI 1325
               F++++ +L+     K    S+ +  RKA EELL +L+++      G ++VF KAG +
Sbjct: 727  YADFKQRYCILNPRTFPK----SKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFL 782

Query: 1326 SRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKNVAVFLAVKDWPWW 1385
             +LE  R++ +S+   LFQA  +G L R +F+K+   R A   IQ N+  F+AVK+WPW 
Sbjct: 783  GQLEAIRDERLSKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPWM 842

Query: 1386 QLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSD 1445
            +L   ++PL+ ++   E++   +EE   L++ LEKSE  R EL+     L  +  DL   
Sbjct: 843  RLFFKIKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQ 902

Query: 1446 LADER-------------FKGDVACQVLESERAERLQAFREV-QELKSKHEQVQKKLGDV 1491
            L  E+              K  +  +    E +ER++   E+  EL ++  +++ +  ++
Sbjct: 903  LQAEQETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFEL 962

Query: 1492 NKQLEEAQQKIQLNDLERNPTGGADEWQMRFDCAQME--NEFLRK--------------- 1534
             K++++ +  +  ++ E+  T    E +++    ++E  NE + K               
Sbjct: 963  KKEIDDLETMLVKSEKEKRTT----EHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQT 1018

Query: 1535 --RLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLL 1592
               L   EE+L S   A  +LEQ++ EL+ A +  +K     +R+ H L  +L+     +
Sbjct: 1019 LDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESM 1078

Query: 1593 ENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQLQQQLKQKE 1652
            EN +S    L ++ +K +L+L+Q   +   EKGL              + QLQ+ +K+ +
Sbjct: 1079 ENLESSQRHLAEELRKKELELSQMNSKVENEKGL--------------VAQLQKTVKELQ 1124

Query: 1653 QEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQQKIQSQQENTIK 1712
             +   LK+++E  +  + ++    +     +A L ERL ++  S+L Q +I  +QE   +
Sbjct: 1125 TQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQ 1184

Query: 1713 QL----EQLRQRFELEIERMKQMHQ---KDREDQEEELEDVRQSCQKRLHQLEMQLEQEY 1765
            +L    E+    FE     +K+ H     + E Q E L+ V+Q  +K    L+++++   
Sbjct: 1185 KLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLL 1244

Query: 1766 EEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGK 1825
               + +   K + E     LC     R           L    A L  V  L   +   K
Sbjct: 1245 TRVEQMTRAKANAE----KLCTLYEER-----------LHEATAKLDKVTQLANDLAAQK 1289

Query: 1826 TSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRL 1885
            T +  E  E +  +LE+ EA   +  + +   T  +E +  +LE  T+++S +       
Sbjct: 1290 TKLWSESGEFLR-RLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSAL------- 1341

Query: 1886 QFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQEQL 1945
                A  L++   D D L E  ++ +++ A+    + ++    +Q    K E + +Q   
Sbjct: 1342 ----AHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQW-RMKYENNVIQ--- 1393

Query: 1946 QVAQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGE 2005
                 R E LE +  + AI  ++ A    + N       + +    L + L D+L  +G+
Sbjct: 1394 -----RTEDLEDAKKELAIRLQEAAEAMGVANARNASLERAR--HQLQLELGDALSDLGK 1446

Query: 2006 ELSQAATSESQQRESSQY---YQRRLEELKADMEELVQREAEA-SRRCMELEKYVEELAA 2061
              S AA  + +Q +S +    ++++ EE +A + +  Q+E +A S   ++L+   EE   
Sbjct: 1447 VRSAAARLDQKQLQSGKALADWKQKHEESQA-LLDASQKEVQALSTELLKLKNTYEESIV 1505

Query: 2062 VRQTLQTDLETSIRRIADLQAALEEVASSDSDTESVQTAVDCGSSGRKEMDNVSILSSQP 2121
             ++TL+ + +     I++L   + E   + ++ E V+  ++      +E   V +   + 
Sbjct: 1506 GQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIE------EEKTEVQVTLEET 1559

Query: 2122 EGSLQ 2126
            EG+L+
Sbjct: 1560 EGALE 1564



 Score =  111 bits (278), Expect = 8e-24
 Identities = 166/780 (21%), Positives = 338/780 (43%), Gaps = 120/780 (15%)

Query: 1402 EQLRAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKI---------------------A 1440
            E+LR KE EL+ +  K+E  + L  +L++    L+++I                     A
Sbjct: 1090 EELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERA 1149

Query: 1441 DLTSDLAD-----ERFKGDVACQ--VLESERAERLQAFREVQE-----------LKSKHE 1482
            DLT DLAD     E   G    Q  + + +  +  +  R+++E           LK +H 
Sbjct: 1150 DLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHA 1209

Query: 1483 QVQKKLGDVNKQLEEAQQKIQLN----DLERNPTGGADEWQMRFDC-AQMENEFLRKRLQ 1537
                +L    + L++ +QK++ +     LE +      E   R    A+       +RL 
Sbjct: 1210 DSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLH 1269

Query: 1538 QCEERLD------SELTARK-ELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCV 1590
            +   +LD      ++L A+K +L  + GE     +  + + +QL R+  + T  +ED   
Sbjct: 1270 EATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRG 1329

Query: 1591 LLE----NQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTS-VRWELGQLQ 1645
             LE    +Q +  H L+K Q+  DL   Q   E   +  L   +++ N   V+W + + +
Sbjct: 1330 QLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRM-KYE 1388

Query: 1646 QQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLW-KLESSALEQQKIQ 1704
              + Q+ ++    K+++ +      E +G  +     +   + +L  +L  +  +  K++
Sbjct: 1389 NNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVR 1448

Query: 1705 SQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQLEMQLEQE 1764
            S       +L+Q + +    +   KQ H++ +   +   ++V Q+    L +L+   E+ 
Sbjct: 1449 S----AAARLDQKQLQSGKALADWKQKHEESQALLDASQKEV-QALSTELLKLKNTYEES 1503

Query: 1765 YEEKQMVLHEKQDLEGLIGTLCDQI--GHRDFDVEKRLRRDLRRTHALLSDVQLLLGTME 1822
               ++ +  E ++L+  I  L +Q+  G ++    +++++ +       ++VQ+   T+E
Sbjct: 1504 IVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEK---TEVQV---TLE 1557

Query: 1823 DGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQL 1882
            + + ++ + E + +H QLE  EAK E        L   L     E+EN  R +    + L
Sbjct: 1558 ETEGALERNESKILHFQLELLEAKAE--------LERKLSEKDEEIENFRRKQQCTIDSL 1609

Query: 1883 Y-------RLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADIGQIQ----ELQLQL 1931
                    + + E   L K+++ED +++   +      ++++   +GQ+Q    +LQ+QL
Sbjct: 1610 QSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQL 1669

Query: 1932 EEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQ---------EAVICDLENKTEFQ 1982
            +++ +    L+EQ+ VA+ R   L+    D   +  Q         E ++   E    F 
Sbjct: 1670 DDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFY 1729

Query: 1983 KV------QIKRFEVLVIRLRDSLIKMGEELSQA----------ATSESQQRESSQYYQR 2026
                    Q K+ E  V R++    ++ +E   A          A + S++ +  Q    
Sbjct: 1730 TQNTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIA 1789

Query: 2027 RLEELKADMEELV----QREAEASRRC-MELEKYVEELAAVRQTLQTDLETSIRRIADLQ 2081
             LE  + +ME+ +    +R AEA +   M   K +++L +  + L+ +LE  IRR A+ Q
Sbjct: 1790 HLERTRENMEQTITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQ 1849



 Score =  106 bits (265), Expect = 3e-22
 Identities = 136/680 (20%), Positives = 282/680 (41%), Gaps = 72/680 (10%)

Query: 1416 RKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESERAERLQAFREVQ 1475
            R+LE+ E L N+L +       +I DL   L  E          L+       +A R+  
Sbjct: 1301 RRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQ-------KAQRDCD 1353

Query: 1476 ELKSKHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPTGGADEWQMRFDCAQMENEFLRKR 1535
             L+ ++E+ Q+   ++++ L +   ++              +W+M+++            
Sbjct: 1354 LLREQYEEEQEVKAELHRTLSKVNAEMV-------------QWRMKYE---------NNV 1391

Query: 1536 LQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQ 1595
            +Q+ E+  D    A+KEL  +L E   A   A      L+R  H L  +L D    L   
Sbjct: 1392 IQRTEDLED----AKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKV 1447

Query: 1596 QSRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEA 1655
            +S    L++KQ +    LA    +    + L +   +E  ++  EL +L+   ++     
Sbjct: 1448 RSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQ 1507

Query: 1656 SQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLE 1715
              L+++ + LQ+    L      G   +  +++    +E    E Q    + E  +++ E
Sbjct: 1508 ETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNE 1567

Query: 1716 QLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEK 1775
                 F+LE+   K   ++   +++EE+E+ R+  Q  +  L+  L+ E + +  V   K
Sbjct: 1568 SKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLK 1627

Query: 1776 QDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLG-------------TME 1822
            + +E  +  +  Q+   +  V +   + L +    + D+Q+ L               + 
Sbjct: 1628 KKMEEDLNEMELQLSCANRQVSE-ATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVA 1686

Query: 1823 DGKTSVSKEELEKVHSQLEQ-------SEAKCEEA--------------LKTQKVLTADL 1861
            + + S+ + ELE + S  EQ       SE +  EA              L  +K L AD+
Sbjct: 1687 ERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADV 1746

Query: 1862 ESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADI 1921
              M  E E + +     +E+  +   E A+L + + + QD +  L ++ ++ + Q+  D+
Sbjct: 1747 ARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHL-ERTRENMEQTITDL 1805

Query: 1922 GQ--IQELQLQLEEAKKEKHKLQEQLQVAQMRIE-YLEQSTVDRAIVSRQEAVICDLENK 1978
             +   +  Q+ L  ++K+  KL+ +++  +  +E  + +S   +    R E  I +L  +
Sbjct: 1806 QKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQ 1865

Query: 1979 TEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQYYQRRLEELKADMEEL 2038
             E  K  + R +  + +L+  +    +++  A T  +Q     +  Q  L E+K   E  
Sbjct: 1866 AEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVA 1925

Query: 2039 VQREAEASRRCMELEKYVEE 2058
              +  +   +  E  K V+E
Sbjct: 1926 ESQVNKLKIKAREFGKKVQE 1945


>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score =  368 bits (945), Expect = e-101
 Identities = 392/1734 (22%), Positives = 775/1734 (44%), Gaps = 221/1734 (12%)

Query: 503  DQAPEDRWYEAEKVWLAQK--DGFTLATVLKPDE----GTADL-PAGRVRLWIDADKTIT 555
            + AP  R  E E++    +  D  T   V +P E    GT      G+V +  +   T+T
Sbjct: 12   EAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKVTVKTEGGATLT 71

Query: 556  EVDEEHVHRANPPELDQVEDLASLISVNESSVLNTLLQRYKAQLLHTCTGPDLIVLQPRG 615
             V ++ V   NPP+ D++ED+A +  ++E +VL  L +RY A +++T +G   + + P  
Sbjct: 72   -VKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYK 130

Query: 616  ------PSVPSAGKVPKGRRDGLPAHIGSMAQRAYWALLNQRRDQSIVALGWSGAGKTTC 669
                  P V +A +  K  R   P HI S++  AY  +L  R +QSI+  G SGAGKT  
Sbjct: 131  WLPVYKPEVVTAYRGKK--RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVN 188

Query: 670  CEQVLEHLVGMA------------GSVDGRVSVEKIRATFTVLRAFGSVSMAHSRSATRF 717
             ++V+++   +A            G + G +  + I A   +L AFG+     + +++RF
Sbjct: 189  TKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISAN-PLLEAFGNAKTVRNDNSSRF 247

Query: 718  SMVMSLDFNATGRITAAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTEL--- 774
               + + F  TG++ +A ++T LLEKSRV  Q + E ++ +F Q+ +    +L   L   
Sbjct: 248  GKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLIT 307

Query: 775  -NLHQMADSSSFGMGVWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHL 833
             N +     S   + V S  + ++  A        A+++LG +  E+ +++++  A+ H 
Sbjct: 308  TNPYDYPFVSQGEISVASIDDQEELMAT-----DSAIDILGFTNEEKVSIYKLTGAVMHY 362

Query: 834  GAAGACKVGRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWGLED 893
            G      +  KQ  R E     AE  G E  +        +   +++ + +   + G  +
Sbjct: 363  G-----NLKFKQKQREE----QAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVG--N 411

Query: 894  EETSSGLKMTGV-DCVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNP 952
            E  + G  +  V + V  +A  +Y+++F  +V+ IN+   +       I V+D  GF+  
Sbjct: 412  EYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIF 471

Query: 953  RHQGKDRAATFEELCHNYAHERLQLLFYQRTFVSTLQRYQEEGVPVQFDLPDPSPGTTVA 1012
                     + E+LC N+ +E+LQ  F    FV   + Y++EG+   F          + 
Sbjct: 472  DFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIE 525

Query: 1013 VVDQNPSQVRLPAGGGAQDARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTEGSS 1072
            ++++                 G+F +L+EE     ++D+    +L      K A  +   
Sbjct: 526  LIEK---------------PMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPK 570

Query: 1073 ALRTCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSLFQA 1132
             ++  +      + H  G   V Y++TGWL + K  L+      +  +S  + L  LF  
Sbjct: 571  VVKG-KAEAHFALIHYAG--VVDYNITGWLEKNKDPLNET-VVGLYQKSAMKTLAQLFSG 626

Query: 1133 RAKLPPVCRAVAGLEGTSQQALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMDALTSMIK 1192
                       A  EG    A +  +    +F +  A  R           ++ L + ++
Sbjct: 627  AQ--------TAEGEGAGGGAKKGGKKKGSSFQTVSALFREN---------LNKLMTNLR 669

Query: 1193 RSRLHFIHCLVPNPVVESRSGQESPPPPQPGRDKPGAGGPLALDIPALRVQLAGFHILEA 1252
             +  HF+ C++PN   E+++                   P A++   +  QL    +LE 
Sbjct: 670  STHPHFVRCIIPN---ETKT-------------------PGAMEHELVLHQLRCNGVLEG 707

Query: 1253 LRLHRTGYADHMGLTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLETLDLEKKAVA 1312
            +R+ R G+   +    F+++++VL+A  + +     + ID +KA E+LL ++D++     
Sbjct: 708  IRICRKGFPSRILYADFKQRYKVLNASAIPE----GQFIDSKKASEKLLASIDIDHTQYK 763

Query: 1313 VGHSQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKN 1372
             GH++VF KAG++  LE+ R+  ++Q I   QA C+GFL+R E++++  RR A  CIQ N
Sbjct: 764  FGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYN 823

Query: 1373 VAVFLAVKDWPWWQLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEKLRNELRQNT 1432
            +  F+ VK WPW +L   ++PLL +    +++   +EE   ++ +L KSE  R EL +  
Sbjct: 824  IRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKM 883

Query: 1433 DLLESKIADL-------------TSDLADERFKGDVACQVLESERAERLQAFREVQ-ELK 1478
              L  +  DL               +  D+  K  +  +    E  ER +   E+  EL 
Sbjct: 884  VTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELT 943

Query: 1479 SKHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPT-----------GGADEWQMRF----D 1523
            +K  +++ +  ++ K +++ +  +   + E++ T            G DE   +      
Sbjct: 944  AKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKK 1003

Query: 1524 CAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTC 1583
              Q  ++     LQ  E+++++   A+ +LEQ++ +L+ + +  KK+   L+R    L  
Sbjct: 1004 ALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEG 1063

Query: 1584 DLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELG- 1642
            DL+     + + ++   +L++K KK + +++           L+ K+  E       LG 
Sbjct: 1064 DLKLAQESIMDIENEKQQLDEKLKKKEFEIS----------NLQSKIEDEQA-----LGI 1108

Query: 1643 QLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQ-- 1700
            QLQ+++K+ +    +L++++E  +  + +     S     +  + ERL +   +   Q  
Sbjct: 1109 QLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIE 1168

Query: 1701 --QKIQSQQENTIKQLEQLRQRFELEIERMKQMHQ---KDREDQEEELEDVRQSCQKRLH 1755
              +K +++ +   + LE+   + E     +++ H     +  +Q + L+ V+Q  +K   
Sbjct: 1169 MNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1228

Query: 1756 QLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQ 1815
            +++M+++      + V   K +LE +  TL DQ+       E++ R        L++D+ 
Sbjct: 1229 EMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQR--------LINDL- 1279

Query: 1816 LLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNK 1875
                T + G+      E  +   QL++ EA   +  + ++  T  +E +  +LE   + K
Sbjct: 1280 ----TAQRGRLQTESGEFSR---QLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAK 1332

Query: 1876 SLVDEQLYRLQFEKADLLKRIDEDQD---DLNELMQKHKDLIAQ--SAADIGQIQELQLQ 1930
            + +   L   + +   L ++ +E+Q+   +L   + K    +AQ  +  +   IQ  + +
Sbjct: 1333 NALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTE-E 1391

Query: 1931 LEEAKKEKHKLQEQLQVAQMRIEYLE-------------QSTVDRAI--VSRQEAVICDL 1975
            LEEAKK   KL ++LQ A+  +E +              Q+ V+  +  V R  A    L
Sbjct: 1392 LEEAKK---KLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAAL 1448

Query: 1976 ENK-TEFQKV------QIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQYYQRRL 2028
            + K   F K+      + +     +   +     +G EL +   +  +  +  +  +R  
Sbjct: 1449 DKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKREN 1508

Query: 2029 EELKADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVA 2088
            + L+ ++ +L ++ AE  +R  ELEK  +++   +  LQ  LE +    A L+    ++ 
Sbjct: 1509 KNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEA---EASLEHEEGKIL 1565

Query: 2089 SSDSDTESVQTAVDCGSSGR-KEMDNVSILSSQPEGSLQSWLSCTLSLATDTMR 2141
                +   V++ VD   + + +E+D +     +   S+QS L   +    D +R
Sbjct: 1566 RIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIR 1619



 Score =  139 bits (349), Expect = 5e-32
 Identities = 215/998 (21%), Positives = 420/998 (42%), Gaps = 143/998 (14%)

Query: 1292 DERKAVEELLETLDLEKKAVAVGHSQVF----LKAGVISRLEKQREKLVSQSIVLFQAAC 1347
            +E   ++E +  L  EKKA+   H Q       +   ++ L K + KL  Q   L     
Sbjct: 986  EEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDL----- 1040

Query: 1348 KGFLSRQEFKKLKIRRLAAQCIQKNVAVFLAVKDWPWWQLLGSLQPLLSATIGTEQLRAK 1407
            +G L +++  ++ + R      ++ +   L +       +    Q L       E+L+ K
Sbjct: 1041 EGSLEQEKKLRMDLERA-----KRKLEGDLKLAQESIMDIENEKQQL------DEKLKKK 1089

Query: 1408 EEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESERAER 1467
            E E++ L+ K+E  + L  +L++    L+++I +L  ++              E+ERA R
Sbjct: 1090 EFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEI--------------EAERASR 1135

Query: 1468 LQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPTGGADEWQMRFDCAQM 1527
             +A              +K+  D++++LEE  ++++         GGA   Q+  +  + 
Sbjct: 1136 AKA--------------EKQRSDLSRELEEISERLE-------EAGGATSAQIEMN-KKR 1173

Query: 1528 ENEFLRKRLQQCEERLDSELTA---RKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCD 1584
            E EF + R    E  L  E TA   RK+    + EL    D  +++  +L+++   +  +
Sbjct: 1174 EAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKME 1233

Query: 1585 LEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQL 1644
            ++D    +E        LEK  +  + QL++   +   ++ L   +T +   ++ E G+ 
Sbjct: 1234 IDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEF 1293

Query: 1645 QQQLKQKEQEASQLKQQ----VEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSA--- 1697
             +QL +KE   SQL +      + +++ KR+L       E  +         L+SS    
Sbjct: 1294 SRQLDEKEALVSQLSRGKQAFTQQIEELKRQL-------EEEIKAKNALAHALQSSRHDC 1346

Query: 1698 -LEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQ 1756
             L +++ + +QE+   +L++   +   E+ + +  ++ D   + EELE+ ++   +RL  
Sbjct: 1347 DLLREQYEEEQESKA-ELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQA 1405

Query: 1757 LEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQL 1816
             E  +E    +   +   KQ L+  +               + L  D+ RT+A  + +  
Sbjct: 1406 AEEHVEAVNAKCASLEKTKQRLQNEV---------------EDLMLDVERTNAACAALDK 1450

Query: 1817 LLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQ--KVLTADLESMHSELENMTRN 1874
                  D   +  K++ E+ H++LE S+ +   +L T+  K+  A  ES+  +LE + R 
Sbjct: 1451 KQRNF-DKILAEWKQKCEETHAELEASQKEAR-SLGTELFKIKNAYEESL-DQLETLKRE 1507

Query: 1875 KSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIA---QSAADI----GQIQEL 1927
               + +++  L  + A+  KRI E +    ++ Q+  +L A   ++ A +    G+I  +
Sbjct: 1508 NKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRI 1567

Query: 1928 QLQLEEAKKE-------KHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQEAVICDLE---- 1976
            QL+L + K E       K +  +QL+   +RI    QST+D  I SR +A+    +    
Sbjct: 1568 QLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGD 1627

Query: 1977 -NKTEFQKVQIKRFEVLVIR--------LRDSLIKMGEELSQAATSESQQRESSQYYQRR 2027
             N+ E Q     R     +R        L+D+ I     L  A  S+   +E     +RR
Sbjct: 1628 LNEMEIQLNHANRMAAEALRNYRNTQGILKDTQI----HLDDALRSQEDLKEQLAMVERR 1683

Query: 2028 LEELKADMEEL--VQREAEASRRCMELEKY-VEELAAVRQTLQTDLETSIRR----IADL 2080
               L+A++EEL     + E SR+  E E     E   +  T  T L  + ++    I+ +
Sbjct: 1684 ANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQM 1743

Query: 2081 QAALEEVASSDSDTE-----SVQTAVDCGSSGRKEMDNVSILSSQPEGSLQSWLSCTLSL 2135
            Q  +E++     + E     ++  A       +KE D  + L    +   Q+     L L
Sbjct: 1744 QGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL 1803

Query: 2136 ATDTMRTPSRQSATSSRILSPRINEEAGDTE----RTQSALALSRARSTNVHSKTSGDKP 2191
              +  +   +      + L  R+ E  G+ E    R   A+   R     V   T   + 
Sbjct: 1804 -DEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEE 1862

Query: 2192 VSPHFVRRQKYCHFGDGEVLAVQRKSTERLEPASSPLA 2229
               + +R Q        +V + +R++ E  E +++ LA
Sbjct: 1863 DRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLA 1900



 Score =  123 bits (308), Expect = 3e-27
 Identities = 140/686 (20%), Positives = 303/686 (44%), Gaps = 74/686 (10%)

Query: 1405 RAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESER 1464
            R  E++L+ L+ K E+ ++L N+L      L+++  + +  L DE+       + L S+ 
Sbjct: 1256 RTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQL-DEK-------EALVSQL 1307

Query: 1465 AERLQAF-REVQELKSKHEQVQKKLGDVNKQLEEAQQKIQL--NDLERNPTGGADEWQM- 1520
            +   QAF ++++ELK + E+  K    +   L+ ++    L     E      A+  +  
Sbjct: 1308 SRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRAL 1367

Query: 1521 ---RFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRK 1577
                 + AQ   ++    +Q+ EE  +    A+K+L Q+L   +   +        L++ 
Sbjct: 1368 SKANTEVAQWRTKYETDAIQRTEELEE----AKKKLAQRLQAAEEHVEAVNAKCASLEKT 1423

Query: 1578 CHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSV 1637
               L  ++ED  + +E   +    L+KKQ+ FD  LA+   +        E   +E  S+
Sbjct: 1424 KQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSL 1483

Query: 1638 RWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSA 1697
              EL +++   ++   +   LK++ + LQ    +L    + G   +  L++   ++E   
Sbjct: 1484 GTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEK 1543

Query: 1698 LEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQL 1757
             E Q    + E +++  E    R +LE+ ++K    +   +++EE++ ++++  + +  +
Sbjct: 1544 CELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESM 1603

Query: 1758 EMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLL 1817
            +  L+ E   +   +  K+ +EG +  +  Q+ H +    + L R+ R T  +L D Q+ 
Sbjct: 1604 QSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEAL-RNYRNTQGILKDTQIH 1662

Query: 1818 LG-------------TMEDGKTSVSKEELEKVHSQLEQSEAKCEEA-------------- 1850
            L               M + + ++ + E+E++ + LEQ+E   + A              
Sbjct: 1663 LDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLL 1722

Query: 1851 -------LKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDL 1903
                   + T+K L  D+  M  E+E++ +     +E+  +   + A + + + ++QD  
Sbjct: 1723 HTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTS 1782

Query: 1904 NELMQKHKDLIAQSAADIGQIQELQLQLEEA--------KKEKHKLQEQLQVAQMRIEYL 1955
              L +  K++          +++LQL+L+EA        KK+  KL+ +++  +  +E  
Sbjct: 1783 AHLERMKKNMEQ-------TVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVE-S 1834

Query: 1956 EQSTVDRAI--VSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATS 2013
            EQ     A+  + + E  + +L  +TE  +  I R + LV +L+  +     +  +A   
Sbjct: 1835 EQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQ 1894

Query: 2014 ESQQRESSQYYQRRLEEL--KADMEE 2037
             +      +  Q  LEE   +AD+ E
Sbjct: 1895 SNTNLAKFRKLQHELEEAEERADIAE 1920



 Score = 92.4 bits (228), Expect = 5e-18
 Identities = 130/614 (21%), Positives = 256/614 (41%), Gaps = 69/614 (11%)

Query: 1404 LRAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESE 1463
            L++   +   LR + E+ ++ + EL++      +++A   +    +  +     +  + +
Sbjct: 1339 LQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKK 1398

Query: 1464 RAERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQKIQ--LNDLERNPTGGA--DEWQ 1519
             A+RLQA  E        E V  K   + K  +  Q +++  + D+ER     A  D+ Q
Sbjct: 1399 LAQRLQAAEE------HVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQ 1452

Query: 1520 MRFDCAQMENEFLRKRLQQCEE---RLDSELTARKELEQKLGELQSAYDGAKKMAHQLKR 1576
              FD      + L +  Q+CEE    L++     + L  +L ++++AY+ +      LKR
Sbjct: 1453 RNFD------KILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKR 1506

Query: 1577 KCHHLTCDLEDTCVLLENQQSRNHELEK-----KQKKFDLQLAQALGESVFEKGLREKVT 1631
            +  +L  ++ D    +     R HELEK     +Q+K +LQ A    E+  E     K+ 
Sbjct: 1507 ENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE-EGKIL 1565

Query: 1632 QENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLW 1691
            +    +     ++ +++ +K++E  QLK+    + +  +  L +     N    LK+++ 
Sbjct: 1566 RIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKM- 1624

Query: 1692 KLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKD----REDQEEELEDVR 1747
                  L + +IQ    N +        R    I +  Q+H  D    +ED +E+L  V 
Sbjct: 1625 ---EGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVE 1681

Query: 1748 QSC---QKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDL 1804
            +     Q  + +L   LEQ    +++   E  D    +  L  Q      + +K+L  D+
Sbjct: 1682 RRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQ-NTSLINTKKKLETDI 1740

Query: 1805 RRTHALLSDV-QLLLGTMEDGKTSVSK-----EELEK---VHSQLEQSEAKCEEALKTQK 1855
             +    + D+ Q      E  K +++      EEL+K     + LE+ +   E+ +K  +
Sbjct: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800

Query: 1856 VLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIA 1915
            +   + E +   L+   +    ++ ++  L+ E     KR  E    L +  ++ K+L  
Sbjct: 1801 LRLDEAEQL--ALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTY 1858

Query: 1916 QSAADIGQIQELQ--------------LQLEEAKKEKH-------KLQEQLQVAQMRIEY 1954
            Q+  D   I  LQ               Q EEA+++ +       KLQ +L+ A+ R + 
Sbjct: 1859 QTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADI 1918

Query: 1955 LEQSTVDRAIVSRQ 1968
             E       + SR+
Sbjct: 1919 AESQVNKLRVKSRE 1932



 Score = 78.2 bits (191), Expect = 1e-13
 Identities = 118/572 (20%), Positives = 238/572 (41%), Gaps = 96/572 (16%)

Query: 1359 LKIRRLAAQCI-----QKNVAVFLAVKDWPWWQLLGSLQPLLSATIGTEQLRAKEEELTT 1413
            L + R  A C      Q+N    LA     W Q        L A+   ++ R+   EL  
Sbjct: 1436 LDVERTNAACAALDKKQRNFDKILA----EWKQKCEETHAELEAS--QKEARSLGTELFK 1489

Query: 1414 LRRKLEKSEKLRNELRQNTDLLESKIADLTSDLAD--------ERFKGDVACQVLESERA 1465
            ++   E+S      L++    L+ +I+DLT  +A+        E+ K  V     E E+ 
Sbjct: 1490 IKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQV-----EQEKC 1544

Query: 1466 ERLQAFREVQELKSKHEQ-----VQKKLGDVNKQLEE--AQQKIQLNDLERNPTGGADEW 1518
            E LQA  E  E   +HE+     +Q +L  V  +++   A++  +++ L+RN     +  
Sbjct: 1545 E-LQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESM 1603

Query: 1519 QMRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKC 1578
            Q   D        +R R        +  +  +K++E  L E++   + A +MA +  R  
Sbjct: 1604 QSTLDAE------IRSR--------NDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNY 1649

Query: 1579 HHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVR 1638
             +    L+DT + L++      +L K+Q     + A  L   + E             +R
Sbjct: 1650 RNTQGILKDTQIHLDDALRSQEDL-KEQLAMVERRANLLQAEIEE-------------LR 1695

Query: 1639 WELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSAL 1698
              L Q ++  K  EQE     ++V++L      L+ +                KLE+   
Sbjct: 1696 ATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKK--------------KLETDI- 1740

Query: 1699 EQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQ--KDREDQEEELEDVRQSCQKRLHQ 1756
               ++Q + E+ +++     ++ +  I     M +  K  +D    LE ++++ ++ +  
Sbjct: 1741 --SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKD 1798

Query: 1757 LEMQLEQEYEEKQMVLH----EKQDLEGLIGTLCDQIGH---RDFDVEKRLRRDLRRTHA 1809
            L+++L+   E +Q+ L     + Q LE  +  L  ++     R+ +  K LR+  RR   
Sbjct: 1799 LQLRLD---EAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVK- 1854

Query: 1810 LLSDVQLLLGTMEDGKTSVSKEEL-EKVHSQLEQSEAKCEEALKTQKVLTADLESMHSEL 1868
                 +L   T ED K  +  ++L +K+ ++++  + + EEA +      A    +  EL
Sbjct: 1855 -----ELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHEL 1909

Query: 1869 ENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQ 1900
            E       + + Q+ +L+ +  ++  ++  ++
Sbjct: 1910 EEAEERADIAESQVNKLRVKSREVHTKVISEE 1941


>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score =  368 bits (945), Expect = e-101
 Identities = 392/1734 (22%), Positives = 775/1734 (44%), Gaps = 221/1734 (12%)

Query: 503  DQAPEDRWYEAEKVWLAQK--DGFTLATVLKPDE----GTADL-PAGRVRLWIDADKTIT 555
            + AP  R  E E++    +  D  T   V +P E    GT      G+V +  +   T+T
Sbjct: 12   EAAPFLRKSERERIEAQNRPFDAKTSVFVAEPKESFVKGTIQSREGGKVTVKTEGGATLT 71

Query: 556  EVDEEHVHRANPPELDQVEDLASLISVNESSVLNTLLQRYKAQLLHTCTGPDLIVLQPRG 615
             V ++ V   NPP+ D++ED+A +  ++E +VL  L +RY A +++T +G   + + P  
Sbjct: 72   -VKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYK 130

Query: 616  ------PSVPSAGKVPKGRRDGLPAHIGSMAQRAYWALLNQRRDQSIVALGWSGAGKTTC 669
                  P V +A +  K  R   P HI S++  AY  +L  R +QSI+  G SGAGKT  
Sbjct: 131  WLPVYKPEVVTAYRGKK--RQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVN 188

Query: 670  CEQVLEHLVGMA------------GSVDGRVSVEKIRATFTVLRAFGSVSMAHSRSATRF 717
             ++V+++   +A            G + G +  + I A   +L AFG+     + +++RF
Sbjct: 189  TKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISAN-PLLEAFGNAKTVRNDNSSRF 247

Query: 718  SMVMSLDFNATGRITAAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTEL--- 774
               + + F  TG++ +A ++T LLEKSRV  Q + E ++ +F Q+ +    +L   L   
Sbjct: 248  GKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLIT 307

Query: 775  -NLHQMADSSSFGMGVWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHL 833
             N +     S   + V S  + ++  A        A+++LG +  E+ +++++  A+ H 
Sbjct: 308  TNPYDYPFVSQGEISVASIDDQEELMAT-----DSAIDILGFTNEEKVSIYKLTGAVMHY 362

Query: 834  GAAGACKVGRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWGLED 893
            G      +  KQ  R E     AE  G E  +        +   +++ + +   + G  +
Sbjct: 363  G-----NLKFKQKQREE----QAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVG--N 411

Query: 894  EETSSGLKMTGV-DCVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNP 952
            E  + G  +  V + V  +A  +Y+++F  +V+ IN+   +       I V+D  GF+  
Sbjct: 412  EYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVARINQQLDTKQPRQYFIGVLDIAGFEIF 471

Query: 953  RHQGKDRAATFEELCHNYAHERLQLLFYQRTFVSTLQRYQEEGVPVQFDLPDPSPGTTVA 1012
                     + E+LC N+ +E+LQ  F    FV   + Y++EG+   F          + 
Sbjct: 472  DFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIE 525

Query: 1013 VVDQNPSQVRLPAGGGAQDARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTEGSS 1072
            ++++                 G+F +L+EE     ++D+    +L      K A  +   
Sbjct: 526  LIEK---------------PMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPK 570

Query: 1073 ALRTCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSLFQA 1132
             ++  +      + H  G   V Y++TGWL + K  L+      +  +S  + L  LF  
Sbjct: 571  VVKG-KAEAHFALIHYAG--VVDYNITGWLEKNKDPLNET-VVGLYQKSAMKTLAQLFSG 626

Query: 1133 RAKLPPVCRAVAGLEGTSQQALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMDALTSMIK 1192
                       A  EG    A +  +    +F +  A  R           ++ L + ++
Sbjct: 627  AQ--------TAEGEGAGGGAKKGGKKKGSSFQTVSALFREN---------LNKLMTNLR 669

Query: 1193 RSRLHFIHCLVPNPVVESRSGQESPPPPQPGRDKPGAGGPLALDIPALRVQLAGFHILEA 1252
             +  HF+ C++PN   E+++                   P A++   +  QL    +LE 
Sbjct: 670  STHPHFVRCIIPN---ETKT-------------------PGAMEHELVLHQLRCNGVLEG 707

Query: 1253 LRLHRTGYADHMGLTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLETLDLEKKAVA 1312
            +R+ R G+   +    F+++++VL+A  + +     + ID +KA E+LL ++D++     
Sbjct: 708  IRICRKGFPSRILYADFKQRYKVLNASAIPE----GQFIDSKKASEKLLASIDIDHTQYK 763

Query: 1313 VGHSQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKN 1372
             GH++VF KAG++  LE+ R+  ++Q I   QA C+GFL+R E++++  RR A  CIQ N
Sbjct: 764  FGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLARVEYQRMVERREAIFCIQYN 823

Query: 1373 VAVFLAVKDWPWWQLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEKLRNELRQNT 1432
            +  F+ VK WPW +L   ++PLL +    +++   +EE   ++ +L KSE  R EL +  
Sbjct: 824  IRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKM 883

Query: 1433 DLLESKIADL-------------TSDLADERFKGDVACQVLESERAERLQAFREVQ-ELK 1478
              L  +  DL               +  D+  K  +  +    E  ER +   E+  EL 
Sbjct: 884  VTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELT 943

Query: 1479 SKHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPT-----------GGADEWQMRF----D 1523
            +K  +++ +  ++ K +++ +  +   + E++ T            G DE   +      
Sbjct: 944  AKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKK 1003

Query: 1524 CAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTC 1583
              Q  ++     LQ  E+++++   A+ +LEQ++ +L+ + +  KK+   L+R    L  
Sbjct: 1004 ALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEG 1063

Query: 1584 DLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELG- 1642
            DL+     + + ++   +L++K KK + +++           L+ K+  E       LG 
Sbjct: 1064 DLKLAQESIMDIENEKQQLDEKLKKKEFEIS----------NLQSKIEDEQA-----LGI 1108

Query: 1643 QLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQ-- 1700
            QLQ+++K+ +    +L++++E  +  + +     S     +  + ERL +   +   Q  
Sbjct: 1109 QLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIE 1168

Query: 1701 --QKIQSQQENTIKQLEQLRQRFELEIERMKQMHQ---KDREDQEEELEDVRQSCQKRLH 1755
              +K +++ +   + LE+   + E     +++ H     +  +Q + L+ V+Q  +K   
Sbjct: 1169 MNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKS 1228

Query: 1756 QLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQ 1815
            +++M+++      + V   K +LE +  TL DQ+       E++ R        L++D+ 
Sbjct: 1229 EMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQR--------LINDL- 1279

Query: 1816 LLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNK 1875
                T + G+      E  +   QL++ EA   +  + ++  T  +E +  +LE   + K
Sbjct: 1280 ----TAQRGRLQTESGEFSR---QLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAK 1332

Query: 1876 SLVDEQLYRLQFEKADLLKRIDEDQD---DLNELMQKHKDLIAQ--SAADIGQIQELQLQ 1930
            + +   L   + +   L ++ +E+Q+   +L   + K    +AQ  +  +   IQ  + +
Sbjct: 1333 NALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTE-E 1391

Query: 1931 LEEAKKEKHKLQEQLQVAQMRIEYLE-------------QSTVDRAI--VSRQEAVICDL 1975
            LEEAKK   KL ++LQ A+  +E +              Q+ V+  +  V R  A    L
Sbjct: 1392 LEEAKK---KLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAAL 1448

Query: 1976 ENK-TEFQKV------QIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQYYQRRL 2028
            + K   F K+      + +     +   +     +G EL +   +  +  +  +  +R  
Sbjct: 1449 DKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKREN 1508

Query: 2029 EELKADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVA 2088
            + L+ ++ +L ++ AE  +R  ELEK  +++   +  LQ  LE +    A L+    ++ 
Sbjct: 1509 KNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEA---EASLEHEEGKIL 1565

Query: 2089 SSDSDTESVQTAVDCGSSGR-KEMDNVSILSSQPEGSLQSWLSCTLSLATDTMR 2141
                +   V++ VD   + + +E+D +     +   S+QS L   +    D +R
Sbjct: 1566 RIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIR 1619



 Score =  139 bits (349), Expect = 5e-32
 Identities = 215/998 (21%), Positives = 420/998 (42%), Gaps = 143/998 (14%)

Query: 1292 DERKAVEELLETLDLEKKAVAVGHSQVF----LKAGVISRLEKQREKLVSQSIVLFQAAC 1347
            +E   ++E +  L  EKKA+   H Q       +   ++ L K + KL  Q   L     
Sbjct: 986  EEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDL----- 1040

Query: 1348 KGFLSRQEFKKLKIRRLAAQCIQKNVAVFLAVKDWPWWQLLGSLQPLLSATIGTEQLRAK 1407
            +G L +++  ++ + R      ++ +   L +       +    Q L       E+L+ K
Sbjct: 1041 EGSLEQEKKLRMDLERA-----KRKLEGDLKLAQESIMDIENEKQQL------DEKLKKK 1089

Query: 1408 EEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESERAER 1467
            E E++ L+ K+E  + L  +L++    L+++I +L  ++              E+ERA R
Sbjct: 1090 EFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEI--------------EAERASR 1135

Query: 1468 LQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPTGGADEWQMRFDCAQM 1527
             +A              +K+  D++++LEE  ++++         GGA   Q+  +  + 
Sbjct: 1136 AKA--------------EKQRSDLSRELEEISERLE-------EAGGATSAQIEMN-KKR 1173

Query: 1528 ENEFLRKRLQQCEERLDSELTA---RKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCD 1584
            E EF + R    E  L  E TA   RK+    + EL    D  +++  +L+++   +  +
Sbjct: 1174 EAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKME 1233

Query: 1585 LEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQL 1644
            ++D    +E        LEK  +  + QL++   +   ++ L   +T +   ++ E G+ 
Sbjct: 1234 IDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEF 1293

Query: 1645 QQQLKQKEQEASQLKQQ----VEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSA--- 1697
             +QL +KE   SQL +      + +++ KR+L       E  +         L+SS    
Sbjct: 1294 SRQLDEKEALVSQLSRGKQAFTQQIEELKRQL-------EEEIKAKNALAHALQSSRHDC 1346

Query: 1698 -LEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQ 1756
             L +++ + +QE+   +L++   +   E+ + +  ++ D   + EELE+ ++   +RL  
Sbjct: 1347 DLLREQYEEEQESKA-ELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQA 1405

Query: 1757 LEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQL 1816
             E  +E    +   +   KQ L+  +               + L  D+ RT+A  + +  
Sbjct: 1406 AEEHVEAVNAKCASLEKTKQRLQNEV---------------EDLMLDVERTNAACAALDK 1450

Query: 1817 LLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQ--KVLTADLESMHSELENMTRN 1874
                  D   +  K++ E+ H++LE S+ +   +L T+  K+  A  ES+  +LE + R 
Sbjct: 1451 KQRNF-DKILAEWKQKCEETHAELEASQKEAR-SLGTELFKIKNAYEESL-DQLETLKRE 1507

Query: 1875 KSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIA---QSAADI----GQIQEL 1927
               + +++  L  + A+  KRI E +    ++ Q+  +L A   ++ A +    G+I  +
Sbjct: 1508 NKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRI 1567

Query: 1928 QLQLEEAKKE-------KHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQEAVICDLE---- 1976
            QL+L + K E       K +  +QL+   +RI    QST+D  I SR +A+    +    
Sbjct: 1568 QLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGD 1627

Query: 1977 -NKTEFQKVQIKRFEVLVIR--------LRDSLIKMGEELSQAATSESQQRESSQYYQRR 2027
             N+ E Q     R     +R        L+D+ I     L  A  S+   +E     +RR
Sbjct: 1628 LNEMEIQLNHANRMAAEALRNYRNTQGILKDTQI----HLDDALRSQEDLKEQLAMVERR 1683

Query: 2028 LEELKADMEEL--VQREAEASRRCMELEKY-VEELAAVRQTLQTDLETSIRR----IADL 2080
               L+A++EEL     + E SR+  E E     E   +  T  T L  + ++    I+ +
Sbjct: 1684 ANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQM 1743

Query: 2081 QAALEEVASSDSDTE-----SVQTAVDCGSSGRKEMDNVSILSSQPEGSLQSWLSCTLSL 2135
            Q  +E++     + E     ++  A       +KE D  + L    +   Q+     L L
Sbjct: 1744 QGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQLRL 1803

Query: 2136 ATDTMRTPSRQSATSSRILSPRINEEAGDTE----RTQSALALSRARSTNVHSKTSGDKP 2191
              +  +   +      + L  R+ E  G+ E    R   A+   R     V   T   + 
Sbjct: 1804 -DEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEE 1862

Query: 2192 VSPHFVRRQKYCHFGDGEVLAVQRKSTERLEPASSPLA 2229
               + +R Q        +V + +R++ E  E +++ LA
Sbjct: 1863 DRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLA 1900



 Score =  123 bits (308), Expect = 3e-27
 Identities = 140/686 (20%), Positives = 303/686 (44%), Gaps = 74/686 (10%)

Query: 1405 RAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESER 1464
            R  E++L+ L+ K E+ ++L N+L      L+++  + +  L DE+       + L S+ 
Sbjct: 1256 RTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQL-DEK-------EALVSQL 1307

Query: 1465 AERLQAF-REVQELKSKHEQVQKKLGDVNKQLEEAQQKIQL--NDLERNPTGGADEWQM- 1520
            +   QAF ++++ELK + E+  K    +   L+ ++    L     E      A+  +  
Sbjct: 1308 SRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRAL 1367

Query: 1521 ---RFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRK 1577
                 + AQ   ++    +Q+ EE  +    A+K+L Q+L   +   +        L++ 
Sbjct: 1368 SKANTEVAQWRTKYETDAIQRTEELEE----AKKKLAQRLQAAEEHVEAVNAKCASLEKT 1423

Query: 1578 CHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSV 1637
               L  ++ED  + +E   +    L+KKQ+ FD  LA+   +        E   +E  S+
Sbjct: 1424 KQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSL 1483

Query: 1638 RWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSA 1697
              EL +++   ++   +   LK++ + LQ    +L    + G   +  L++   ++E   
Sbjct: 1484 GTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEK 1543

Query: 1698 LEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQL 1757
             E Q    + E +++  E    R +LE+ ++K    +   +++EE++ ++++  + +  +
Sbjct: 1544 CELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESM 1603

Query: 1758 EMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLL 1817
            +  L+ E   +   +  K+ +EG +  +  Q+ H +    + L R+ R T  +L D Q+ 
Sbjct: 1604 QSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEAL-RNYRNTQGILKDTQIH 1662

Query: 1818 LG-------------TMEDGKTSVSKEELEKVHSQLEQSEAKCEEA-------------- 1850
            L               M + + ++ + E+E++ + LEQ+E   + A              
Sbjct: 1663 LDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLL 1722

Query: 1851 -------LKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDL 1903
                   + T+K L  D+  M  E+E++ +     +E+  +   + A + + + ++QD  
Sbjct: 1723 HTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTS 1782

Query: 1904 NELMQKHKDLIAQSAADIGQIQELQLQLEEA--------KKEKHKLQEQLQVAQMRIEYL 1955
              L +  K++          +++LQL+L+EA        KK+  KL+ +++  +  +E  
Sbjct: 1783 AHLERMKKNMEQ-------TVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVE-S 1834

Query: 1956 EQSTVDRAI--VSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATS 2013
            EQ     A+  + + E  + +L  +TE  +  I R + LV +L+  +     +  +A   
Sbjct: 1835 EQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQ 1894

Query: 2014 ESQQRESSQYYQRRLEEL--KADMEE 2037
             +      +  Q  LEE   +AD+ E
Sbjct: 1895 SNTNLAKFRKLQHELEEAEERADIAE 1920



 Score = 92.4 bits (228), Expect = 5e-18
 Identities = 130/614 (21%), Positives = 256/614 (41%), Gaps = 69/614 (11%)

Query: 1404 LRAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESE 1463
            L++   +   LR + E+ ++ + EL++      +++A   +    +  +     +  + +
Sbjct: 1339 LQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKK 1398

Query: 1464 RAERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQKIQ--LNDLERNPTGGA--DEWQ 1519
             A+RLQA  E        E V  K   + K  +  Q +++  + D+ER     A  D+ Q
Sbjct: 1399 LAQRLQAAEE------HVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQ 1452

Query: 1520 MRFDCAQMENEFLRKRLQQCEE---RLDSELTARKELEQKLGELQSAYDGAKKMAHQLKR 1576
              FD      + L +  Q+CEE    L++     + L  +L ++++AY+ +      LKR
Sbjct: 1453 RNFD------KILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKR 1506

Query: 1577 KCHHLTCDLEDTCVLLENQQSRNHELEK-----KQKKFDLQLAQALGESVFEKGLREKVT 1631
            +  +L  ++ D    +     R HELEK     +Q+K +LQ A    E+  E     K+ 
Sbjct: 1507 ENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHE-EGKIL 1565

Query: 1632 QENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLW 1691
            +    +     ++ +++ +K++E  QLK+    + +  +  L +     N    LK+++ 
Sbjct: 1566 RIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKM- 1624

Query: 1692 KLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKD----REDQEEELEDVR 1747
                  L + +IQ    N +        R    I +  Q+H  D    +ED +E+L  V 
Sbjct: 1625 ---EGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVE 1681

Query: 1748 QSC---QKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDL 1804
            +     Q  + +L   LEQ    +++   E  D    +  L  Q      + +K+L  D+
Sbjct: 1682 RRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQ-NTSLINTKKKLETDI 1740

Query: 1805 RRTHALLSDV-QLLLGTMEDGKTSVSK-----EELEK---VHSQLEQSEAKCEEALKTQK 1855
             +    + D+ Q      E  K +++      EEL+K     + LE+ +   E+ +K  +
Sbjct: 1741 SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQ 1800

Query: 1856 VLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIA 1915
            +   + E +   L+   +    ++ ++  L+ E     KR  E    L +  ++ K+L  
Sbjct: 1801 LRLDEAEQL--ALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTY 1858

Query: 1916 QSAADIGQIQELQ--------------LQLEEAKKEKH-------KLQEQLQVAQMRIEY 1954
            Q+  D   I  LQ               Q EEA+++ +       KLQ +L+ A+ R + 
Sbjct: 1859 QTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADI 1918

Query: 1955 LEQSTVDRAIVSRQ 1968
             E       + SR+
Sbjct: 1919 AESQVNKLRVKSRE 1932



 Score = 78.2 bits (191), Expect = 1e-13
 Identities = 118/572 (20%), Positives = 238/572 (41%), Gaps = 96/572 (16%)

Query: 1359 LKIRRLAAQCI-----QKNVAVFLAVKDWPWWQLLGSLQPLLSATIGTEQLRAKEEELTT 1413
            L + R  A C      Q+N    LA     W Q        L A+   ++ R+   EL  
Sbjct: 1436 LDVERTNAACAALDKKQRNFDKILA----EWKQKCEETHAELEAS--QKEARSLGTELFK 1489

Query: 1414 LRRKLEKSEKLRNELRQNTDLLESKIADLTSDLAD--------ERFKGDVACQVLESERA 1465
            ++   E+S      L++    L+ +I+DLT  +A+        E+ K  V     E E+ 
Sbjct: 1490 IKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQV-----EQEKC 1544

Query: 1466 ERLQAFREVQELKSKHEQ-----VQKKLGDVNKQLEE--AQQKIQLNDLERNPTGGADEW 1518
            E LQA  E  E   +HE+     +Q +L  V  +++   A++  +++ L+RN     +  
Sbjct: 1545 E-LQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESM 1603

Query: 1519 QMRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKC 1578
            Q   D        +R R        +  +  +K++E  L E++   + A +MA +  R  
Sbjct: 1604 QSTLDAE------IRSR--------NDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNY 1649

Query: 1579 HHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVR 1638
             +    L+DT + L++      +L K+Q     + A  L   + E             +R
Sbjct: 1650 RNTQGILKDTQIHLDDALRSQEDL-KEQLAMVERRANLLQAEIEE-------------LR 1695

Query: 1639 WELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSAL 1698
              L Q ++  K  EQE     ++V++L      L+ +                KLE+   
Sbjct: 1696 ATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKK--------------KLETDI- 1740

Query: 1699 EQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQ--KDREDQEEELEDVRQSCQKRLHQ 1756
               ++Q + E+ +++     ++ +  I     M +  K  +D    LE ++++ ++ +  
Sbjct: 1741 --SQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKD 1798

Query: 1757 LEMQLEQEYEEKQMVLH----EKQDLEGLIGTLCDQIGH---RDFDVEKRLRRDLRRTHA 1809
            L+++L+   E +Q+ L     + Q LE  +  L  ++     R+ +  K LR+  RR   
Sbjct: 1799 LQLRLD---EAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVK- 1854

Query: 1810 LLSDVQLLLGTMEDGKTSVSKEEL-EKVHSQLEQSEAKCEEALKTQKVLTADLESMHSEL 1868
                 +L   T ED K  +  ++L +K+ ++++  + + EEA +      A    +  EL
Sbjct: 1855 -----ELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHEL 1909

Query: 1869 ENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQ 1900
            E       + + Q+ +L+ +  ++  ++  ++
Sbjct: 1910 EEAEERADIAESQVNKLRVKSREVHTKVISEE 1941


>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
            sapiens]
          Length = 1983

 Score =  367 bits (943), Expect = e-101
 Identities = 461/1887 (24%), Positives = 819/1887 (43%), Gaps = 269/1887 (14%)

Query: 510  WYEAEKVWLA-QKDGFTLATVLKPDEGTADLPAGRVRLWIDADKTITEVDEEHVHRANPP 568
            W   ++VW+  ++D +  A V     G      GRV +    D+ +  V E  +   NPP
Sbjct: 71   WDGKKRVWVPDEQDAYVEAEVKSEATG------GRVTVETK-DQKVLMVREAELQPMNPP 123

Query: 569  ELDQVEDLASLISVNESSVLNTLLQRYKAQLLHTCTGPDLIVLQP-RGPSVPSAGKVP-- 625
              D +ED+A +  +NE+SVL+ L QRY   +++T +G   + + P +   V +A  V   
Sbjct: 124  RFDLLEDMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCVTINPYKWLPVYTASVVAAY 183

Query: 626  KG-RRDGLPAHIGSMAQRAYWALLNQRRDQSIVALGWSGAGKTTCCEQVLEHLVGMAGSV 684
            KG RR   P HI ++A  AY  +L  R +QS++  G SGAGKT   ++V+++   +A   
Sbjct: 184  KGKRRSDSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAGKTVNTKRVIQYFAIVAALG 243

Query: 685  DGRVSVEKIRATFT-------------VLRAFGSVSMAHSRSATRFSMVMSLDFNATGRI 731
            DG     +  AT T              + AFG+     + +++RF   + + F  +G++
Sbjct: 244  DGPGKKAQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPSGKL 303

Query: 732  TAAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTELNLHQMADSSSF-GMGVW 790
             +A + + LLEKSRV  Q  GE ++ V+ Q+L+G   +L+  L L        F   GV 
Sbjct: 304  ASADIDSYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQDMLLLSMNPYDYHFCSQGVI 363

Query: 791  SKPEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAAGACKVGRKQFMRFE 850
            +   D             AM++LG S  E+ A ++++ A+ H G      +  KQ  R E
Sbjct: 364  T--VDNMNDGEELIATDHAMDILGFSVDEKCACYKIVGALLHFG-----NMKFKQKQREE 416

Query: 851  WANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWGLEDEETSSGLKMTGVDCVEG 910
                 AEA G E  +            +++ +     R G E       ++   V  V  
Sbjct: 417  ----QAEADGTESADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQV-VFAVGA 471

Query: 911  MASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQGKDRAATFEELCHNY 970
            +A   Y  LF  +VS IN++  +       I V+D  GF+           +FE+LC N+
Sbjct: 472  LAKATYDRLFRWLVSRINQTLDTKLPRQFFIGVLDIAGFEIFEFN------SFEQLCINF 525

Query: 971  AHERLQLLFYQRTFVSTLQRYQEEGVP---VQFDLPDPSPGTTVAVVDQNPSQVRLPAGG 1027
             +E+LQ  F Q  FV   + Y+ EG+    + F L D  P   +                
Sbjct: 526  TNEKLQQFFNQHMFVLEQEEYKREGIDWVFIDFGL-DLQPCIDL---------------- 568

Query: 1028 GAQDARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTEGSSALRTCEQPLQCEIFH 1087
              +   G+  +L+EE     +SD+    +L      K    +     +  +     E+ H
Sbjct: 569  -IEKPLGILSILEEECMFPKASDASFRAKLYDNHAGKSPNFQQPRPDKKRKYQAHFEVVH 627

Query: 1088 QLGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSLFQARAKLPPVCRAVAGLE 1147
              G  P  Y + GWL + K  L+    P +  +S+   L +L++  A     C       
Sbjct: 628  YAGVVP--YSIVGWLEKNKDPLNETVVP-IFQKSQNRLLATLYENYA---GSCSTEPPKS 681

Query: 1148 GTSQQALQRSRMVRRTFASSLAAVRRKAPCSQI-KLQMDALTSMIKRSRLHFIHCLVPNP 1206
            G  +         +R  A+S   V      SQ+ K  ++ L + ++ ++ HF+ C+VPN 
Sbjct: 682  GVKE---------KRKKAASFQTV------SQLHKENLNKLMTNLRATQPHFVRCIVPN- 725

Query: 1207 VVESRSGQESPPPPQPGRDKPGAGGPLALDIPALRVQLAGFHILEALRLHRTGYADHMGL 1266
              E+++                   P  +D   +  QL    +LE +R+ R G+ + +  
Sbjct: 726  --ENKT-------------------PGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLLY 764

Query: 1267 TRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLETLDLEKKAVAVGHSQVFLKAGVIS 1326
            T FR+++++L+       +     +D RKA E+LL +LDL+      GH++VF KAG++ 
Sbjct: 765  TDFRQRYRILN----PSAIPDDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVFFKAGLLG 820

Query: 1327 RLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKNVAVFLAVKDWPWWQ 1386
             LE+ R++ +++ + L QA  +G L R E+++L   R A   IQ N+  F AVK+W W +
Sbjct: 821  VLEELRDQRLAKVLTLLQARSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAVKNWSWMK 880

Query: 1387 LLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDL 1446
            L   ++PLL +    E+L A   EL  LR  L  +E  R EL +    +  +  DL   L
Sbjct: 881  LFFKMKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQL 940

Query: 1447 ---------ADER----FKGDVACQVLESERAERLQAFREV--------QELKSKHEQVQ 1485
                     A+ER     K  V  +    E +ERL+   EV        ++L+ +  +++
Sbjct: 941  QAEQDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELK 1000

Query: 1486 KKLGDVNKQLEEAQQKIQLNDLE-RNPT---GGADEWQMRF----DCAQMENEFLRKRLQ 1537
            K + D+   L +A+++ Q  + + +N T      DE   R        Q  ++     LQ
Sbjct: 1001 KDIDDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQ 1060

Query: 1538 QCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQS 1597
              E+R+ +   A+  LEQ++ +L+ + +  KK+    +R    L  DL+ T   + +   
Sbjct: 1061 AEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQ 1120

Query: 1598 RNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELG-QLQQQLKQKEQEAS 1656
               +LE+K KK D +L+Q          L  +V  E       LG Q+Q+++K+ +  A 
Sbjct: 1121 DKQQLEEKLKKKDSELSQ----------LSLRVEDEQL-----LGAQMQKKIKELQARAE 1165

Query: 1657 QLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQ----QKIQSQQENTIK 1712
            +L++++E  +  +  +    +     +  L ERL +   ++  Q    +K +++     +
Sbjct: 1166 ELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRR 1225

Query: 1713 QLEQLRQRFELEIERMKQMHQK---DREDQEEELEDVRQSCQKRLHQLEMQLEQEYEEKQ 1769
            +LE+   R E  +  +++   +   +  +Q + L+ VRQ  +K   +L M+++      +
Sbjct: 1226 ELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVE 1285

Query: 1770 MVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTM--EDGKTS 1827
             +   K   E L  T  DQ+      VE+  R+        L+D     G +  E G+ S
Sbjct: 1286 TLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQ--------LADASTQRGRLQTESGELS 1337

Query: 1828 VSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQF 1887
               EE E + SQL + +A   ++          LE +  +LE  ++ KS +   +  L+ 
Sbjct: 1338 RLLEEKECLISQLSRGKALAAQS----------LEELRRQLEEESKAKSALAHAVQALRH 1387

Query: 1888 EKADLLKRIDED----QDDLNELMQKHKDLIAQ--SAADIGQIQELQLQLEEAKK----- 1936
            +  DLL+   E+    Q +L  L+ K    +AQ  S  +   IQ  + +LEEAKK     
Sbjct: 1388 D-CDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTE-ELEEAKKKLALR 1445

Query: 1937 ------------------EKHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQEAVICDLENK 1978
                              EK KL+ Q +   + +E LE++T   A + +++     LE  
Sbjct: 1446 LQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLE-LERATSAAAALDKKQR---HLERA 1501

Query: 1979 TEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQYYQRRLEELKADMEEL 2038
             E ++ Q +  +  +   +     +G EL +      +  E+ +  +R  + L+ ++ +L
Sbjct: 1502 LEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDL 1561

Query: 2039 VQREAEASRRCMELEKYVEELAAVRQTLQTDLETS-----IRRIADLQAALE-------- 2085
              + + + +   ELEK  + L   +  +Q  LE +     +     L+  LE        
Sbjct: 1562 TDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEV 1621

Query: 2086 --EVASSDSD-----------TESVQTAVDCGSSGRKEMDNVSILSSQPEGSLQSWLSCT 2132
              ++A  D +            ES+Q ++D  +  R E      L  + EG L       
Sbjct: 1622 DRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNE---ALRLKKKMEGDLN---DLE 1675

Query: 2133 LSLATDTMRTPSRQSATSSRILSPRINEE-AGDTERTQSALAL---SRARSTNVHSKTSG 2188
            L L   T +    Q+AT  R++  ++ EE AG  E  + A  L   ++A         + 
Sbjct: 1676 LQLGHATRQATEAQAAT--RLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAE 1733

Query: 2189 DKPVSPHFVRRQKYCHFGDGEVLAVQRKSTERLEPASSPLASRSTNTSPLS-REKLPSPS 2247
             + +     + ++     + E+L    ++TERL          S NT  L+ ++KL +  
Sbjct: 1734 LEELRAALEQGERSRRLAEQELL----EATERLN------LLHSQNTGLLNQKKKLEADL 1783

Query: 2248 AALSEFVEGLRRKRAQRGQGSTLGLED 2274
            A LS  VE   ++R +  + +   + D
Sbjct: 1784 AQLSGEVEEAAQERREAEEKAKKAITD 1810



 Score =  120 bits (302), Expect = 1e-26
 Identities = 177/852 (20%), Positives = 347/852 (40%), Gaps = 112/852 (13%)

Query: 1274 QVLDAPLLKKLMSTSEGIDERKAVEELLETLDLEKKAVAVGHSQVFLKAGVISRLEKQRE 1333
            Q+L A + KK+         +   EEL E L+ E+ A A    Q    A  +  L ++ E
Sbjct: 1147 QLLGAQMQKKIKEL------QARAEELEEELEAERAARARVEKQRAEAARELEELSERLE 1200

Query: 1334 KLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKNVAVFLAVKDWPWWQLLGSLQP 1393
            +    S     A  +    ++E +  ++RR   +   ++ A   A++           Q 
Sbjct: 1201 EAGGAS-----AGQREGCRKREAELGRLRRELEEAALRHEATVAALR---------RKQA 1246

Query: 1394 LLSATIGTEQLRAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKG 1453
              +A +G        E++ +L+R  +K EK ++ELR   D L + +  LT   A      
Sbjct: 1247 EGAAELG--------EQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKAS----A 1294

Query: 1454 DVACQVLESE------RAERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQKI----- 1502
            +  C+  E +      + E LQ  R++ +  ++  ++Q + G++++ LEE +  I     
Sbjct: 1295 EKLCRTYEDQLSEAKIKVEELQ--RQLADASTQRGRLQTESGELSRLLEEKECLISQLSR 1352

Query: 1503 --------------QLNDLERNPTGGADEWQ-MRFDCAQMENEFLRKRLQQCE------- 1540
                          QL +  +  +  A   Q +R DC  +  +   +   Q E       
Sbjct: 1353 GKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSK 1412

Query: 1541 -----------------ERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTC 1583
                             +R +    A+K+L  +L E +   + A      L++    L  
Sbjct: 1413 ANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQT 1472

Query: 1584 DLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQ 1643
            + ED  + LE   S    L+KKQ+  +  L +   +    +   E   +E+  +  EL +
Sbjct: 1473 ESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFR 1532

Query: 1644 LQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQQKI 1703
            L+   ++  +    LK++ + LQ+   +L    SL    +  L++    LE    E Q  
Sbjct: 1533 LRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAA 1592

Query: 1704 QSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQLEMQLEQ 1763
              + E  ++  E    R +LE+ ++K    +   +++EE  ++R++ Q+ +  L+  L+ 
Sbjct: 1593 LEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDA 1652

Query: 1764 EYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKR------LRRDLRRTHALLSDVQLL 1817
            E   +   L  K+ +EG +  L  Q+GH      +       ++  L+   A   + Q L
Sbjct: 1653 ETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRL 1712

Query: 1818 LGTMEDG------KTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENM 1871
               + +       + S+   ELE++ + LEQ E     A +     T  L  +HS+   +
Sbjct: 1713 AAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGL 1772

Query: 1872 TRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQL 1931
               K        +L+ + A L   ++E   +  E  +K K  I  +A    ++++ Q   
Sbjct: 1773 LNQKK-------KLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTS 1825

Query: 1932 EEAKKEKHKLQEQLQVAQMRIEYLEQSTV--DRAIVSRQEAVICDLENKTEFQKVQIKRF 1989
               ++ K  L++ ++  Q R+E  EQ+ +   +  V + EA + +LE   E    Q K  
Sbjct: 1826 AHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELE--AELDAEQKKHA 1883

Query: 1990 EVLV-IRLRDSLIKMGEELSQAATSESQQRESSQYYQRRLE-ELKADMEELVQREAEASR 2047
            E L  +R  +  +K   EL+  A  + +     Q    +L+ ++K+   +  + E +A+ 
Sbjct: 1884 EALKGVRKHERRVK---ELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANT 1940

Query: 2048 RCMELEKYVEEL 2059
               +  K   EL
Sbjct: 1941 NLAKYRKAQHEL 1952



 Score = 65.9 bits (159), Expect = 5e-10
 Identities = 96/529 (18%), Positives = 222/529 (41%), Gaps = 72/529 (13%)

Query: 1401 TEQLRAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVL 1460
            T    A +++   L R LE+  +   E+++  +  + +   L ++L   R   + A + L
Sbjct: 1485 TSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEAL 1544

Query: 1461 ESERAERLQAFREV--------------QELKSKHEQVQKKLGDVNKQLEEAQQKIQLND 1506
            E+ + E      E+              QEL+   + ++ +  ++   LEEA+  ++L +
Sbjct: 1545 ETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEE 1604

Query: 1507 LERNPTGGADEWQMRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDG 1566
             +          +++ + +Q++ E  RK  ++ EE  +     R+  ++ +  LQ++ D 
Sbjct: 1605 TKT--------LRIQLELSQVKAEVDRKLAEKDEECAN----LRRNHQRAVESLQASLDA 1652

Query: 1567 AKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGL 1626
              +  ++  R    +  DL D  + L +   +  E +   +    QL +       E+ L
Sbjct: 1653 ETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRL 1712

Query: 1627 REKVTQENTSVRWELGQLQQQLKQ-----KEQEASQLKQQVEMLQDHKR-ELLGSPSLG- 1679
              ++ ++  ++      L  +L++     ++ E S+   + E+L+  +R  LL S + G 
Sbjct: 1713 AAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGL 1772

Query: 1680 ----ENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQRFELE------IERMK 1729
                +   A L +   ++E +A E+++ + + +  I     + +  + E      +ERMK
Sbjct: 1773 LNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMK 1832

Query: 1730 QMHQKDREDQEEELEDVRQSC----QKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTL 1785
            +  ++   + +  LE+  Q+     +K++ +LE ++ +   E ++   +K+  E L G  
Sbjct: 1833 KTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVREL--EAELDAEQKKHAEALKG-- 1888

Query: 1786 CDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSKEEL-EKVHSQLEQSE 1844
                          +R+  RR   L    +      ED K     ++L +K+ S+++  +
Sbjct: 1889 --------------VRKHERRVKELAYQAE------EDRKNLARMQDLVDKLQSKVKSYK 1928

Query: 1845 AKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLL 1893
             + EEA +      A       EL++      + + Q  +L+    D L
Sbjct: 1929 RQFEEAEQQANTNLAKYRKAQHELDDAEERADMAETQANKLRARTRDAL 1977


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score =  363 bits (931), Expect = 2e-99
 Identities = 378/1622 (23%), Positives = 732/1622 (45%), Gaps = 201/1622 (12%)

Query: 542  GRVRLWIDADKTITEVDEEHVHRANPPELDQVEDLASLISVNESSVLNTLLQRYKAQLLH 601
            G+V +  + ++T+  V  E V+  NPP+ D++ED+A L  +NE +VL  L  RY + +++
Sbjct: 58   GKVTVETEDNRTLV-VKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIY 116

Query: 602  TCTGPDLIVLQPRGPSVPSAGKVPKG----RRDGLPAHIGSMAQRAYWALLNQRRDQSIV 657
            T +G   + + P         +V +G    +R   P HI S++  AY  +L  R +QSI+
Sbjct: 117  TYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSIL 176

Query: 658  ALGWSGAGKTTCCEQVLEHLVGMAGSVD-GRVSVEKIRATFT--------VLRAFGSVSM 708
              G SGAGKT   ++V+++   +A + D  +    K++ T          +L AFG+   
Sbjct: 177  ITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAKT 236

Query: 709  AHSRSATRFSMVMSLDFNATGRITAAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDL 768
              + +++RF   + + F  TG++ +A ++T LLEKSRV  Q + E ++ +F Q+L+    
Sbjct: 237  VRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKP 296

Query: 769  DLRTELNLHQMADSSSF---GMGVWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAVWR 825
            +L   L +        F   G  + +  +D ++  A       A+++LG +  E+  +++
Sbjct: 297  ELIELLLITTNPYDYPFISQGEILVASIDDAEELLAT----DSAIDILGFTPEEKSGLYK 352

Query: 826  VLAAIYHLGAAGACKVGRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFG 885
            +  A+ H G      +  KQ  R E     AE  G E  +        +   +++ + F 
Sbjct: 353  LTGAVMHYG-----NMKFKQKQREE----QAEPDGTEVADKTAYLMGLNSSDLLKALCFP 403

Query: 886  PSRWGLEDEETSSGLKMTGVD-CVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVV 944
              + G  +E  + G  +  V   V  ++  +Y++LF  +V+ IN+   +       I V+
Sbjct: 404  RVKVG--NEYVTKGQTVDQVHHAVNALSKSVYEKLFLWMVTRINQQLDTKLPRQHFIGVL 461

Query: 945  DSPGFQNPRHQGKDRAATFEELCHNYAHERLQLLFYQRTFVSTLQRYQEEGVPVQFDLPD 1004
            D  GF+   +       + E+LC N+ +E+LQ  F    FV   + Y++EG+   F    
Sbjct: 462  DIAGFEIFEYN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFG 515

Query: 1005 PSPGTTVAVVDQNPSQVRLPAGGGAQDARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKK 1064
                  + ++++                 G+F +L+EE     ++D+    +L      K
Sbjct: 516  MDLAACIELIEK---------------PMGIFSILEEECMFPKATDTSFKNKLYDQHLGK 560

Query: 1065 GAGTEGSSALRTCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKRE 1124
                +    ++   +     + H  G   V Y ++GWL + K  L+             E
Sbjct: 561  SNNFQKPKVVKGRAEA-HFSLIHYAG--TVDYSVSGWLEKNKDPLN-------------E 604

Query: 1125 ELRSLFQARAKLPPVCRAVAGLEGT--SQQALQRSRMVRRTFASSLAAVRRKAPCSQIKL 1182
             +  L+Q  +      R +A L  T  +  A    + V +   SS   V      +  + 
Sbjct: 605  TVVGLYQKSSN-----RLLAHLYATFATADADSGKKKVAKKKGSSFQTVS-----ALFRE 654

Query: 1183 QMDALTSMIKRSRLHFIHCLVPNPVVESRSGQESPPPPQPGRDKPGAGGPLALDIPALRV 1242
             ++ L S ++ +  HF+ C++PN   E+++                   P A++   +  
Sbjct: 655  NLNKLMSNLRTTHPHFVRCIIPN---ETKT-------------------PGAMEHSLVLH 692

Query: 1243 QLAGFHILEALRLHRTGYADHMGLTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLE 1302
            QL    +LE +R+ R G+ + +    F+++++VL+A  + +     + ID +KA E+LL 
Sbjct: 693  QLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPE----GQFIDSKKACEKLLA 748

Query: 1303 TLDLEKKAVAVGHSQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIR 1362
            ++D++      GH++VF KAG++  LE+ R+  +++ I   QA C+GFL R EF+K+  R
Sbjct: 749  SIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGFLMRVEFQKMVQR 808

Query: 1363 RLAAQCIQKNVAVFLAVKDWPWWQLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSE 1422
            R +  CIQ N+  F+ VK WPW +L   ++PLL +    +++   +EE    + +L KSE
Sbjct: 809  RESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSE 868

Query: 1423 KLRNELRQNTDLLESKIADL-------------TSDLADERFKGDVACQVLESERAERLQ 1469
              R EL +    L  +  DL               +  D+  K     +    E  ER +
Sbjct: 869  AKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTERAE 928

Query: 1470 AFREVQ-ELKSKHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPT-----------GGADE 1517
               E+  EL +K  +++ +  ++ K +++ +  +   + E++ T            G DE
Sbjct: 929  DEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDE 988

Query: 1518 WQMRF----DCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQ 1573
               +        Q  ++     LQ  E++++S    + +LEQ++ +L+S+ +  KK+   
Sbjct: 989  TIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVD 1048

Query: 1574 LKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQE 1633
            L+R    L  DL+     + + ++   +L+++ KK D +  Q          L+ KV  E
Sbjct: 1049 LERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQ----------LQSKVEDE 1098

Query: 1634 NTSVRWELG-QLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWK 1692
             T     LG Q Q+++K+ +    +L++++E  +  + +     S     +  L ERL +
Sbjct: 1099 QT-----LGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEE 1153

Query: 1693 LESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDRED-------QEEELED 1745
                   Q ++  ++E    +L +  +   L+ E M    +K   D       Q + L+ 
Sbjct: 1154 AGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQR 1213

Query: 1746 VRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLR 1805
            V+Q  +K   + +++++      + V   K +LE +  TL DQ+        +    +++
Sbjct: 1214 VKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSE-----ARGKNEEIQ 1268

Query: 1806 RTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESMH 1865
            R+ + L+  +  L T E G+ S   EE E + SQL +S          ++  T   E + 
Sbjct: 1269 RSLSELTTQKSRLQT-EAGELSRQLEEKESIVSQLSRS----------KQAFTQQTEELK 1317

Query: 1866 SELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQD---DLNELMQKHKDLIAQ--SAAD 1920
             +LE   + K+ +   L   + +   L ++ +E+Q+   +L   + K    +AQ  +  +
Sbjct: 1318 RQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYE 1377

Query: 1921 IGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVD-----RAIVSRQEAVICDL 1975
               IQ  + +LEEAKK   KL ++LQ ++ ++E +           + +    E ++ D+
Sbjct: 1378 TDAIQRTE-ELEEAKK---KLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDV 1433

Query: 1976 ENKTEFQKVQIKR---FEVLVIRLRDSLIKMGEELSQAATSESQQRESSQYYQRRLEELK 2032
            E          K+   F+ ++   +    +   EL +A+  ES+   +  +  +   E  
Sbjct: 1434 ERANSLAAALDKKQRNFDKVLAEWKTKCEESQAEL-EASLKESRSLSTELFKLKNAYEEA 1492

Query: 2033 ADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRI----ADLQAALEEVA 2088
             D  E V+RE +   +  E+    E++A   +T+  +LE S ++I    AD+Q ALEE  
Sbjct: 1493 LDQLETVKRENKNLEQ--EIADLTEQIAENGKTIH-ELEKSRKQIELEKADIQLALEEAE 1549

Query: 2089 SS 2090
            ++
Sbjct: 1550 AA 1551



 Score =  136 bits (342), Expect = 3e-31
 Identities = 156/728 (21%), Positives = 323/728 (44%), Gaps = 103/728 (14%)

Query: 1408 EEELTTLRRKLEKSEKLRNELRQNTDLLES-------KIADLTSDLA--DERFKGD--VA 1456
            E+++  L   LE+ +KLR +L +N   LE         I DL +D    DER K      
Sbjct: 1029 EQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEY 1088

Query: 1457 CQV---LESERAERLQAFREVQELKSKHEQVQKKL--------------GDVNKQLEEAQ 1499
            CQ+   +E E+   LQ  ++++EL+++ E++++++               D  ++LEE  
Sbjct: 1089 CQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELS 1148

Query: 1500 QKIQLNDLERNPTGGADEWQMRFDCAQMENEFLRKRLQQCEERLDSELTA---RKELEQK 1556
            ++++         GG    Q+  +  + E EFL+ R    E  L  E      RK+    
Sbjct: 1149 ERLE-------EAGGVTSTQIELN-KKREAEFLKLRRDLEEATLQHEAMVAALRKKHADS 1200

Query: 1557 LGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQA 1616
            + EL    D  +++  +L+++      +++D    +E+       LEK  +  + QL++A
Sbjct: 1201 VAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEA 1260

Query: 1617 LGESVFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKREL---L 1673
             G++   +    ++T + + ++ E G+L +QL++KE   SQL +  +       EL   L
Sbjct: 1261 RGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQL 1320

Query: 1674 GSPSLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQ 1733
               +  +N +A   +         L +++ + +QE    +L++   +   E+ + +  ++
Sbjct: 1321 EEENKAKNALAHALQS--SRHDCDLLREQYEEEQEGKA-ELQRALSKANSEVAQWRTKYE 1377

Query: 1734 KDREDQEEELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRD 1793
             D   + EELE+ ++   +RL   E Q+E    +   +   KQ L+G +           
Sbjct: 1378 TDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEV----------- 1426

Query: 1794 FDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKT 1853
                + L  D+ R ++L + +        D K     + L +  ++ E+S+A+ E +LK 
Sbjct: 1427 ----EDLMVDVERANSLAAAL--------DKKQRNFDKVLAEWKTKCEESQAELEASLKE 1474

Query: 1854 QKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDL 1913
             + L+ +L  + +  E        V  +   L+ E ADL ++I E+   ++EL +  K +
Sbjct: 1475 SRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQI 1534

Query: 1914 IAQSAADIGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLE-QSTVDRAIVSRQEAV- 1971
              + A       ++QL LEEA+       E+ ++ ++++E  + +S +DR I  + E + 
Sbjct: 1535 ELEKA-------DIQLALEEAEAALE--HEEAKILRIQLELTQVKSEIDRKIAEKDEEIE 1585

Query: 1972 ---------------ICDLENKTEFQKVQIKR-----FEVLVIRLRDSLIKMGEELSQAA 2011
                             D E ++  + +++K+        + I+L  +  +  E L    
Sbjct: 1586 QLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLR 1645

Query: 2012 TSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLE 2071
            + + Q +++    Q  L++     E+L ++ A   RR   L+  VEEL A  +  +   +
Sbjct: 1646 SVQGQLKDT----QLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARK 1701

Query: 2072 TSIRRIAD 2079
             + + + D
Sbjct: 1702 LAEQELLD 1709



 Score =  129 bits (325), Expect = 3e-29
 Identities = 148/728 (20%), Positives = 316/728 (43%), Gaps = 95/728 (13%)

Query: 1409 EELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESERAERL 1468
            E++  L+R  +K EK ++E +   D L S +  ++   A+     +  C+ LE + +E  
Sbjct: 1206 EQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANL----EKICRTLEDQLSEAR 1261

Query: 1469 QAFREVQ----ELKSKHEQVQKKLGDVNKQLEEAQQ-------------------KIQLN 1505
                E+Q    EL ++  ++Q + G++++QLEE +                    K QL 
Sbjct: 1262 GKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLE 1321

Query: 1506 DLERNPTGGADEWQM-RFDCAQMENEFLRKR-----LQQCEERLDSELT----------- 1548
            +  +     A   Q  R DC  +  ++  ++     LQ+   + +SE+            
Sbjct: 1322 EENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAI 1381

Query: 1549 --------ARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNH 1600
                    A+K+L Q+L + +   +        L++    L  ++ED  V +E   S   
Sbjct: 1382 QRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAA 1441

Query: 1601 ELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEASQLKQ 1660
             L+KKQ+ FD  LA+   +    +   E   +E+ S+  EL +L+   ++   +   +K+
Sbjct: 1442 ALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKR 1501

Query: 1661 QVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQR 1720
            + + L+    +L    +     +  L++   ++E    + Q    + E  ++  E    R
Sbjct: 1502 ENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILR 1561

Query: 1721 FELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEG 1780
             +LE+ ++K    +   +++EE+E ++++ Q+ +  ++  L+ E   +   +  K+ +EG
Sbjct: 1562 IQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEG 1621

Query: 1781 LIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSKE--------- 1831
             +  +  Q+ H +    + L+  LR     L D QL L     G+  + ++         
Sbjct: 1622 DLNEIEIQLSHANRQAAETLKH-LRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRAN 1680

Query: 1832 ----ELEKVHSQLEQSEAKCEEA---------------------LKTQKVLTADLESMHS 1866
                E+E++ + LEQ+E   + A                     + T+K L  DL  + S
Sbjct: 1681 LLQAEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQS 1740

Query: 1867 ELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADI-GQIQ 1925
            E+E+ +R+    +E+  +   + A + + + ++QD    L +  K+L  Q+  D+  ++ 
Sbjct: 1741 EVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNL-EQTVKDLQHRLD 1799

Query: 1926 EL-QLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAI-VSRQEAVICDLENKTEFQK 1983
            E  QL L+  KK+  KL+ +++  +  +E  ++   +    + + E  + +L  ++E  +
Sbjct: 1800 EAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDR 1859

Query: 1984 VQIKRFEVLVIRLR---DSLIKMGEELSQAATSESQQRESSQYYQRRLEELKADMEELVQ 2040
              + R + LV +L+    S  +  EE  + A +   +   +Q+     EE +AD+ E   
Sbjct: 1860 KNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEE-RADIAESQV 1918

Query: 2041 REAEASRR 2048
             +  A  R
Sbjct: 1919 NKLRAKTR 1926



 Score = 97.1 bits (240), Expect = 2e-19
 Identities = 104/483 (21%), Positives = 224/483 (46%), Gaps = 64/483 (13%)

Query: 1650 QKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQQ-KIQSQQE 1708
            + E+E + +K++ +  +D   EL  S +  +     L+E+L  L     + Q ++Q++ E
Sbjct: 845  ETEKEMATMKEEFQKTKD---ELAKSEAKRKE----LEEKLVTLVQEKNDLQLQVQAESE 897

Query: 1709 NTIKQLEQ----LRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQLEMQLEQE 1764
            N +   E+    ++ +F+LE  ++K++   +R + EEE+     + +++L     +L+++
Sbjct: 898  NLLDAEERCDQLIKAKFQLEA-KIKEV--TERAEDEEEINAELTAKKRKLEDECSELKKD 954

Query: 1765 YEEKQMVL----HEKQDLEGLIGTLCDQIGHRDFDVEK--RLRRDLRRTHA-LLSDVQLL 1817
             ++ ++ L     EK   E  +  L +++   D  + K  R ++ L+  H   L D+Q  
Sbjct: 955  IDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQA- 1013

Query: 1818 LGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELE-------- 1869
                E+ K +     L K  S+LEQ     E +L+ +K L  DLE    +LE        
Sbjct: 1014 ----EEDKVN----SLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQE 1065

Query: 1870 ---NMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADIGQIQE 1926
               ++  +K  +DE+L +  FE   L  +++++Q    +  +K K+L A+       I+E
Sbjct: 1066 SILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQAR-------IEE 1118

Query: 1927 LQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQI 1986
            L+ ++E  +  + K ++Q       +E L +   +   V+  +    +L  K E + +++
Sbjct: 1119 LEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQI---ELNKKREAEFLKL 1175

Query: 1987 KR--------FEVLVIRLR----DSLIKMGEELSQAATSESQQRESSQYYQRRLEELKAD 2034
            +R         E +V  LR    DS+ ++GE++      + +  +    ++  +++L + 
Sbjct: 1176 RRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSS 1235

Query: 2035 MEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSDSDT 2094
            ME + + +A   + C  LE  + E     + +Q  L     + + LQ    E++    + 
Sbjct: 1236 MESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEK 1295

Query: 2095 ESV 2097
            ES+
Sbjct: 1296 ESI 1298



 Score = 73.2 bits (178), Expect = 3e-12
 Identities = 117/580 (20%), Positives = 234/580 (40%), Gaps = 84/580 (14%)

Query: 1722 ELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQL-----EMQLEQEYEEKQMVLHEKQ 1776
            E E+  MK+  QK + D+  + E  R+  +++L  L     ++QL+ + E + ++  E++
Sbjct: 847  EKEMATMKEEFQKTK-DELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEER 905

Query: 1777 DLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSKE--ELE 1834
                     CDQ+    F +E +++    R      D + +   +   K  +  E  EL+
Sbjct: 906  ---------CDQLIKAKFQLEAKIKEVTERAE----DEEEINAELTAKKRKLEDECSELK 952

Query: 1835 KVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLK 1894
            K    LE + AK E+          +  +  ++++N+T   S +DE + +L  EK  L +
Sbjct: 953  KDIDDLELTLAKVEK----------EKHATENKVKNLTEELSGLDETIAKLTREKKALQE 1002

Query: 1895 RIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEY 1954
               +  DDL     K   L    +    Q+++L+  LE+ KK +  L+   +  +  ++ 
Sbjct: 1003 AHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKL 1062

Query: 1955 LEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSE 2014
             ++S             I DLEN  +              +L + L K   E  Q  +  
Sbjct: 1063 AQES-------------ILDLENDKQ--------------QLDERLKKKDFEYCQLQSKV 1095

Query: 2015 SQQRESSQYYQRRLEELKADMEELVQR-EAEASRRCM----------ELEKYVEELAAVR 2063
              ++     +Q++++EL+A +EEL +  EAE + R            ELE+  E L    
Sbjct: 1096 EDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAG 1155

Query: 2064 QTLQTDLETSIRRIADLQAALEEVASSDSDTESVQTAV-----DCGSSGRKEMDNVSILS 2118
                T +E + +R A+      ++  +    E++  A+     D  +   +++DN+  + 
Sbjct: 1156 GVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVK 1215

Query: 2119 SQPEGSLQSWLSCTLSLATDTMRTPSRQSATSSRI---LSPRINEEAGDTERTQSALALS 2175
             + E   +S     +   + +M + S+  A   +I   L  +++E  G  E  Q +L+  
Sbjct: 1216 QKLEKE-KSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSEL 1274

Query: 2176 RARSTNVH------SKTSGDKPVSPHFVRRQKYCHFGDGEVLAVQRKSTERLEPASSPLA 2229
              + + +       S+   +K      + R K       E L  Q +   + + A +   
Sbjct: 1275 TTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHAL 1334

Query: 2230 SRSTNTSPLSREKLPSPSAALSEFVEGLRRKRAQRGQGST 2269
              S +   L RE+        +E    L +  ++  Q  T
Sbjct: 1335 QSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRT 1374


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
            sapiens]
          Length = 1939

 Score =  360 bits (925), Expect = 8e-99
 Identities = 398/1738 (22%), Positives = 774/1738 (44%), Gaps = 231/1738 (13%)

Query: 503  DQAPEDRWYEAEKVWLAQK--DGFTLATVLKPDEG-----TADLPAGRVRLWIDADKTIT 555
            + AP  R  E E++    K  D  T   V+ P E            G+V    +A  T+T
Sbjct: 12   EAAPFLRKSERERIEAQNKPFDAKTSVFVVDPKESFVKATVQSREGGKVTAKTEAGATVT 71

Query: 556  EVDEEHVHRANPPELDQVEDLASLISVNESSVLNTLLQRYKAQLLHTCTGPDLIVLQP-R 614
             V ++ V   NPP+ D++ED+A +  ++E +VL  L +RY A +++T +G   + + P +
Sbjct: 72   -VKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYK 130

Query: 615  GPSVPSAGKVPKGR---RDGLPAHIGSMAQRAYWALLNQRRDQSIVALGWSGAGKTTCCE 671
               V +A  V   R   R   P HI S++  AY  +L  R +QSI+  G SGAGKT   +
Sbjct: 131  WLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTK 190

Query: 672  QVLEHLVGMA------------GSVDGRVSVEKIRATFTVLRAFGSVSMAHSRSATRFSM 719
            +V+++   +A            G + G +  + I A   +L AFG+     + +++RF  
Sbjct: 191  RVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISAN-PLLEAFGNAKTVRNDNSSRFGK 249

Query: 720  VMSLDFNATGRITAAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTELNLHQM 779
             + + F  TG++ +A ++T LLEKSRV  Q + E ++ +F Q+++    DL   L +   
Sbjct: 250  FIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTN 309

Query: 780  ADSSSF-GMGVWSKP--EDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAA 836
                +F   G  + P  +D+++  A       A+E+LG +  E+ +++++  A+ H G  
Sbjct: 310  PYDYAFVSQGEITVPSIDDQEELMAT----DSAIEILGFTSDERVSIYKLTGAVMHYGN- 364

Query: 837  GACKVGRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWGLEDEET 896
                      M+F+      +A     E  + A +  +L            R  + +E  
Sbjct: 365  ----------MKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYV 414

Query: 897  SSGLKMTGV-DCVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQ 955
            + G  +  V + V  +A  +Y ++F  +V+ IN+   +       I V+D  GF+     
Sbjct: 415  TKGQTVQQVYNAVGALAKAVYDKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFN 474

Query: 956  GKDRAATFEELCHNYAHERLQLLFYQRTFVSTLQRYQEEGVPVQFDLPDPSPGTTVAVVD 1015
                  + E+LC N+ +E+LQ  F    FV   + Y++EG+   F          + +++
Sbjct: 475  ------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIE 528

Query: 1016 QNPSQVRLPAGGGAQDARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTEGSSALR 1075
            +                 G+F +L+EE     ++D+    +L      K    +     +
Sbjct: 529  K---------------PMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAK 573

Query: 1076 TCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSLFQARAK 1135
              +      + H  G   V Y++ GWL + K  L+             E +  L+Q  A 
Sbjct: 574  G-KPEAHFSLIHYAG--TVDYNIAGWLDKNKDPLN-------------ETVVGLYQKSA- 616

Query: 1136 LPPVCRAVAGLEGTSQQALQRSRMVRRTFAS--SLAAVRRKAPCSQIKLQMDALTSMIKR 1193
            +  +     G  G   +A    +  ++  +S  +++A+ R+         ++ L + ++ 
Sbjct: 617  MKTLALLFVGATGAEAEAGGGKKGGKKKGSSFQTVSALFRE--------NLNKLMTNLRS 668

Query: 1194 SRLHFIHCLVPNPVVESRSGQESPPPPQPGRDKPGAGGPLALDIPALRVQLAGFHILEAL 1253
            +  HF+ C++PN   E+++                   P A++   +  QL    +LE +
Sbjct: 669  THPHFVRCIIPN---ETKT-------------------PGAMEHELVLHQLRCNGVLEGI 706

Query: 1254 RLHRTGYADHMGLTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLETLDLEKKAVAV 1313
            R+ R G+   +    F+++++VL+A  + +     + ID +KA E+LL ++D++      
Sbjct: 707  RICRKGFPSRILYADFKQRYKVLNASAIPE----GQFIDSKKASEKLLGSIDIDHTQYKF 762

Query: 1314 GHSQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKNV 1373
            GH++VF KAG++  LE+ R++ ++Q I   QA C+GFL+R E++K+  RR +  CIQ NV
Sbjct: 763  GHTKVFFKAGLLGLLEEMRDEKLAQLITRTQAMCRGFLARVEYQKMVERRESIFCIQYNV 822

Query: 1374 AVFLAVKDWPWWQLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEKLRNELRQNTD 1433
              F+ VK WPW +L   ++PLL +    +++   +EE    + +L K+E  R EL +   
Sbjct: 823  RAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMV 882

Query: 1434 LLESKIADL-------------TSDLADERFKGDVACQVLESERAERLQAFREVQ-ELKS 1479
             L  +  DL               +  D+  K  +  +    E  ER +   E+  EL +
Sbjct: 883  TLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTA 942

Query: 1480 KHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPT-----------GGADEWQMRF----DC 1524
            K  +++ +  ++ K +++ +  +   + E++ T            G DE   +       
Sbjct: 943  KKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKA 1002

Query: 1525 AQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCD 1584
             Q  ++     LQ  E+++++   A+ +LEQ++ +L+ + +  KK+   L+R    L  D
Sbjct: 1003 LQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGD 1062

Query: 1585 L---EDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWEL 1641
            L   +++ + +EN +    +L++K KK + +++          GL+ K+  E       L
Sbjct: 1063 LKLAQESTMDIENDK---QQLDEKLKKKEFEMS----------GLQSKIEDEQA-----L 1104

Query: 1642 G-QLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQ 1700
            G QLQ+++K+ +    +L++++E  +  + +     S     +  + ERL +   +   Q
Sbjct: 1105 GMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQ 1164

Query: 1701 ----QKIQSQQENTIKQLEQLRQRFELEIERMKQMHQ---KDREDQEEELEDVRQSCQKR 1753
                +K +++ +   + LE+   + E     +++ H     +  +Q + L+ V+Q  +K 
Sbjct: 1165 IEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKE 1224

Query: 1754 LHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGH--RDFDVEKRLRRDLRRTHALL 1811
              +++M+++      + V   K +LE +   L DQ+       + ++RL  DL    A L
Sbjct: 1225 KSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARL 1284

Query: 1812 SDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENM 1871
                      E G+ S   +E + + SQL +           ++  T  +E +  +LE  
Sbjct: 1285 Q--------TESGEYSRQLDEKDTLVSQLSRG----------KQAFTQQIEELKRQLEEE 1326

Query: 1872 TRNKSLVDEQLYRLQFEKADLLKRIDEDQD---DLNELMQKHKDLIAQ--SAADIGQIQE 1926
             + KS +   L   + +   L ++ +E+Q+   +L   M K    +AQ  +  +   IQ 
Sbjct: 1327 IKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQR 1386

Query: 1927 LQLQLEEAKKEKHKLQEQLQVAQMRIE--------------YLEQSTVDRAI-VSRQEAV 1971
             + +LEEAKK   KL ++LQ A+  +E               L+    D  I V R  A 
Sbjct: 1387 TE-ELEEAKK---KLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAA 1442

Query: 1972 ICDLENK-TEFQKVQI---KRFEVLVIRLRDSLIK---MGEELSQAATSESQQRESSQYY 2024
               L+ K   F K+     ++ E     L  S  +   +  EL +   +  +  +  +  
Sbjct: 1443 CAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETL 1502

Query: 2025 QRRLEELKADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAAL 2084
            +R  + L+ ++ +L ++ AE  +R  ELEK  +++   +  LQ  LE +    A L+   
Sbjct: 1503 KRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEA---EASLEHEE 1559

Query: 2085 EEVASSDSDTESVQTAVDCGSSGR-KEMDNVSILSSQPEGSLQSWLSCTLSLATDTMR 2141
             ++     +   V++ VD   + + +E+D +     +   S+QS L   +    D +R
Sbjct: 1560 GKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIR 1617



 Score =  134 bits (337), Expect = 1e-30
 Identities = 198/933 (21%), Positives = 392/933 (42%), Gaps = 137/933 (14%)

Query: 1292 DERKAVEELLETLDLEKKAVAVGHSQVF----LKAGVISRLEKQREKLVSQSIVLFQAAC 1347
            +E   ++E +  L  EKKA+   H Q       +   ++ L K + KL  Q   L     
Sbjct: 984  EEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDL----- 1038

Query: 1348 KGFLSRQEFKKLKIRRLAAQCIQKNVAVFLAVKDWPWWQLLGSLQPLLSATIGTEQLRAK 1407
            +G L +++  ++ + R      ++ +   L +       +    Q L       E+L+ K
Sbjct: 1039 EGSLEQEKKIRMDLERA-----KRKLEGDLKLAQESTMDIENDKQQL------DEKLKKK 1087

Query: 1408 EEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESERAER 1467
            E E++ L+ K+E  + L  +L++    L+++I +L  ++              E+ERA R
Sbjct: 1088 EFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEI--------------EAERASR 1133

Query: 1468 LQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPTGGADEWQMRFDCAQM 1527
             +A              +K+  D++++LEE  ++++         GGA   Q+  +  + 
Sbjct: 1134 AKA--------------EKQRSDLSRELEEISERLE-------EAGGATSAQIEMN-KKR 1171

Query: 1528 ENEFLRKRLQQCEERLDSELTA---RKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCD 1584
            E EF + R    E  L  E TA   RK+    + EL    D  +++  +L+++   +  +
Sbjct: 1172 EAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKME 1231

Query: 1585 LEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQL 1644
            ++D    +E        LEK  +  + QL++   +   ++ L   +T +   ++ E G+ 
Sbjct: 1232 IDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEY 1291

Query: 1645 QQQLKQKEQEASQLK-------QQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSA 1697
             +QL +K+   SQL        QQ+E L+    E + + S   + +   +     L    
Sbjct: 1292 SRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQY 1351

Query: 1698 LEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQL 1757
             E+Q+ +++       L++   +   E+ + +  ++ D   + EELE+ ++   +RL   
Sbjct: 1352 EEEQEAKAE-------LQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDA 1404

Query: 1758 EMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLL 1817
            E  +E    +   +   KQ L+  +               + L  D+ RT+A  + +   
Sbjct: 1405 EEHVEAVNAKCASLEKTKQRLQNEV---------------EDLMIDVERTNAACAALDKK 1449

Query: 1818 LGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQ--KVLTADLESMHSELENMTRNK 1875
                 D   +  K++ E+ H++LE S+ K   +L T+  K+  A  ES+  +LE + R  
Sbjct: 1450 QRNF-DKILAEWKQKCEETHAELEASQ-KESRSLSTELFKIKNAYEESL-DQLETLKREN 1506

Query: 1876 SLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIA---QSAADI----GQIQELQ 1928
              + +++  L  + A+  KRI E +    ++ Q+  +L A   ++ A +    G+I  +Q
Sbjct: 1507 KNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQ 1566

Query: 1929 LQLEEAKKE-------KHKLQEQLQVAQMRIEYLEQSTVDRAIVSRQEAVICDLE----- 1976
            L+L + K E       K +  +Q++   +RI    QST+D  I SR +A+    +     
Sbjct: 1567 LELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDL 1626

Query: 1977 NKTEFQKVQIKRFEVLVIR--------LRDSLIKMGEELSQAATSESQQRESSQYYQRRL 2028
            N+ E Q     R     +R        L+D+ +     L  A  S+   +E     +RR 
Sbjct: 1627 NEMEIQLNHANRMAAEALRNYRNTQAILKDTQL----HLDDALRSQEDLKEQLAMVERRA 1682

Query: 2029 EELKADMEEL--VQREAEASRRCMELEKY-VEELAAVRQTLQTDLETSIRR----IADLQ 2081
              L+A++EEL     + E SR+  E E     E   +  T  T L  + ++    I+ +Q
Sbjct: 1683 NLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQ 1742

Query: 2082 AALEEVASSDSDTE-----SVQTAVDCGSSGRKEMDNVSILSSQPEGSLQSWLSCTLSLA 2136
              +E++     + E     ++  A       +KE D  + L    + +L+  +       
Sbjct: 1743 GEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKK-NLEQTVKDLQHRL 1801

Query: 2137 TDTMRTPSRQSATSSRILSPRINEEAGDTERTQ 2169
             +  +   +      + L  R+ E  G+ E  Q
Sbjct: 1802 DEAEQLALKGGKKQIQKLEARVRELEGEVESEQ 1834



 Score =  129 bits (325), Expect = 3e-29
 Identities = 144/696 (20%), Positives = 315/696 (45%), Gaps = 79/696 (11%)

Query: 1405 RAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESER 1464
            RA E++L+ ++ K E+ ++L N+L      L+++  + +  L DE+         L S+ 
Sbjct: 1254 RALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQL-DEK-------DTLVSQL 1305

Query: 1465 AERLQAF-REVQELKSKHEQ-----------VQKKLGD---VNKQLEEAQQ-KIQLNDLE 1508
            +   QAF ++++ELK + E+           +Q    D   + +Q EE Q+ K +L    
Sbjct: 1306 SRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAM 1365

Query: 1509 RNPTGGADEWQMRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAK 1568
                    +W+ +++   ++      R ++ EE       A+K+L Q+L + +   +   
Sbjct: 1366 SKANSEVAQWRTKYETDAIQ------RTEELEE-------AKKKLAQRLQDAEEHVEAVN 1412

Query: 1569 KMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLRE 1628
                 L++    L  ++ED  + +E   +    L+KKQ+ FD  LA+   +        E
Sbjct: 1413 AKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELE 1472

Query: 1629 KVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKE 1688
               +E+ S+  EL +++   ++   +   LK++ + LQ    +L    + G   +  L++
Sbjct: 1473 ASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEK 1532

Query: 1689 RLWKLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELEDVRQ 1748
               ++E    E Q    + E +++  E    R +LE+ ++K    +   +++EE++ +++
Sbjct: 1533 IKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKR 1592

Query: 1749 SCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTH 1808
            +  + +  ++  L+ E   +   +  K+ +EG +  +  Q+ H +    + L R+ R T 
Sbjct: 1593 NHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEAL-RNYRNTQ 1651

Query: 1809 ALLSDVQLLLG-------------TMEDGKTSVSKEELEKVHSQLEQSEAKCEEA----- 1850
            A+L D QL L               M + + ++ + E+E++ + LEQ+E   + A     
Sbjct: 1652 AILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELL 1711

Query: 1851 ----------------LKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLK 1894
                            + T+K L  D+  +  E+E++ +     +E+  +   + A + +
Sbjct: 1712 DASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAE 1771

Query: 1895 RIDEDQDDLNELMQKHKDLIAQSAADI-GQIQEL-QLQLEEAKKEKHKLQEQLQVAQMRI 1952
             + ++QD    L +  K+L  Q+  D+  ++ E  QL L+  KK+  KL+ +++  +  +
Sbjct: 1772 ELKKEQDTSAHLERMKKNL-EQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEV 1830

Query: 1953 EYLEQSTVDRAI-VSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAA 2011
            E  ++  V+    + + E  + +L  +TE  +  I R + LV +L+    K+     QA 
Sbjct: 1831 ESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQ---AKVKSYKRQAE 1887

Query: 2012 TSESQQRESSQYYQRRLEELKADMEELVQREAEASR 2047
             +E Q   +   ++R   EL+   E     E++ ++
Sbjct: 1888 EAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNK 1923



 Score = 92.8 bits (229), Expect = 4e-18
 Identities = 129/612 (21%), Positives = 254/612 (41%), Gaps = 65/612 (10%)

Query: 1404 LRAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESE 1463
            L++   +   LR + E+ ++ + EL++      S++A   +     +++ D   +  E E
Sbjct: 1337 LQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRT-----KYETDAIQRTEELE 1391

Query: 1464 RAERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQKIQ--LNDLERNPTGGA--DEWQ 1519
             A++  A R +Q+ +   E V  K   + K  +  Q +++  + D+ER     A  D+ Q
Sbjct: 1392 EAKKKLAQR-LQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQ 1450

Query: 1520 MRFDCAQMENEFLRKRLQQCEE---RLDSELTARKELEQKLGELQSAYDGAKKMAHQLKR 1576
              FD      + L +  Q+CEE    L++     + L  +L ++++AY+ +      LKR
Sbjct: 1451 RNFD------KILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKR 1504

Query: 1577 KCHHLTCDLEDTCVLLENQQSRNHELEK-----KQKKFDLQLAQALGESVFEKGLREKVT 1631
            +  +L  ++ D    +     R HELEK     +Q+K +LQ A    E+  E     K+ 
Sbjct: 1505 ENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHE-EGKIL 1563

Query: 1632 QENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLW 1691
            +    +     ++ +++ +K++E  Q+K+    + +  +  L +     N    LK+++ 
Sbjct: 1564 RIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKM- 1622

Query: 1692 KLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKD----REDQEEELEDVR 1747
                  L + +IQ    N +        R    I +  Q+H  D    +ED +E+L  V 
Sbjct: 1623 ---EGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVE 1679

Query: 1748 QSC---QKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDL 1804
            +     Q  + +L   LEQ    +++   E  D    +  L  Q      + +K+L  D+
Sbjct: 1680 RRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQ-NTSLINTKKKLETDI 1738

Query: 1805 RRTHALLSDV-QLLLGTMEDGKTSVSKEELEKVHSQLEQ-SEAKCEEALKTQKVLTADLE 1862
             +    + D+ Q      E  K +++   +     + EQ + A  E   K  +    DL+
Sbjct: 1739 SQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQ 1798

Query: 1863 SMHSELENMT-----RNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQS 1917
                E E +      +    ++ ++  L+ E     KR  E    L +  +K K+L  Q+
Sbjct: 1799 HRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQT 1858

Query: 1918 AADIGQIQELQ--------------LQLEEAKKEKH-------KLQEQLQVAQMRIEYLE 1956
              D   I  LQ               Q EEA+++ +       ++Q +L+ A+ R +  E
Sbjct: 1859 EEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAE 1918

Query: 1957 QSTVDRAIVSRQ 1968
                   + SR+
Sbjct: 1919 SQVNKLRVKSRE 1930



 Score = 77.8 bits (190), Expect = 1e-13
 Identities = 107/524 (20%), Positives = 224/524 (42%), Gaps = 85/524 (16%)

Query: 1402 EQLRAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLAD--------ERFKG 1453
            ++ R+   EL  ++   E+S      L++    L+ +I+DLT  +A+        E+ K 
Sbjct: 1476 KESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKK 1535

Query: 1454 DVACQVLESERAERLQAFREVQELKSKHEQ-----VQKKLGDVNKQLEE--AQQKIQLND 1506
             V     E E++E LQA  E  E   +HE+     +Q +L  V  +++   A++  +++ 
Sbjct: 1536 QV-----EQEKSE-LQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQ 1589

Query: 1507 LERNPTGGADEWQMRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDG 1566
            ++RN     +  Q   D        +R R        +  +  +K++E  L E++   + 
Sbjct: 1590 MKRNHIRIVESMQSTLDAE------IRSR--------NDAIRLKKKMEGDLNEMEIQLNH 1635

Query: 1567 AKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGL 1626
            A +MA +  R   +    L+DT + L++      +L K+Q     + A  L   + E   
Sbjct: 1636 ANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDL-KEQLAMVERRANLLQAEIEE--- 1691

Query: 1627 REKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGL 1686
                      +R  L Q ++  K  EQE     ++V++L      L+ +           
Sbjct: 1692 ----------LRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKK--------- 1732

Query: 1687 KERLWKLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQ--KDREDQEEELE 1744
                 KLE+      +IQ + E+ I++     ++ +  I     M +  K  +D    LE
Sbjct: 1733 -----KLETDI---SQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 1784

Query: 1745 DVRQSCQKRLHQLEMQLEQEYEEKQMVLH----EKQDLEGLIGTLCDQIGH---RDFDVE 1797
             ++++ ++ +  L+ +L+   E +Q+ L     + Q LE  +  L  ++     R+ +  
Sbjct: 1785 RMKKNLEQTVKDLQHRLD---EAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAV 1841

Query: 1798 KRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSKEEL-EKVHSQLEQSEAKCEEALKTQKV 1856
            K LR+  R+        +L   T ED K  +  ++L +K+ ++++  + + EEA +   V
Sbjct: 1842 KGLRKHERKVK------ELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNV 1895

Query: 1857 LTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQ 1900
              +    +  ELE       + + Q+ +L+ +  ++  +I  ++
Sbjct: 1896 NLSKFRRIQHELEEAEERADIAESQVNKLRVKSREVHTKIISEE 1939


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score =  355 bits (910), Expect = 4e-97
 Identities = 378/1679 (22%), Positives = 747/1679 (44%), Gaps = 215/1679 (12%)

Query: 551  DKTITEVDEEHVHRANPPELDQVEDLASLISVNESSVLNTLLQRYKAQLLHTCTGPDLIV 610
            D  +  ++ + V   NPP+ D++ED+A +  ++E +VL  L +RY A +++T +G   + 
Sbjct: 66   DDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVT 125

Query: 611  LQPRG------PSVPSAGKVPKGRRDGLPAHIGSMAQRAYWALLNQRRDQSIVALGWSGA 664
            + P        P V +A +  K  R   P HI S++  AY  +L  R +QSI+  G SGA
Sbjct: 126  VNPYKWLPVYKPEVVAAYRGKK--RQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGA 183

Query: 665  GKTTCCEQVLEHLVGMA-----------GSVDGRVSVEKIRATFTVLRAFGSVSMAHSRS 713
            GKT   ++V+++   +A           G + G +  + I+A   +L AFG+     + +
Sbjct: 184  GKTVNTKRVIQYFATIAVTGDKKKETQPGKMQGTLEDQIIQAN-PLLEAFGNAKTVRNDN 242

Query: 714  ATRFSMVMSLDFNATGRITAAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTE 773
            ++RF   + + F ATG++ +A ++T LLEKSRV  Q   E ++ +F Q+++    +L   
Sbjct: 243  SSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPELIDL 302

Query: 774  LNLHQMADSSSF---GMGVWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAI 830
            L +        F   G    +  +D ++  A       A+++LG S  E+  ++++  A+
Sbjct: 303  LLISTNPFDFPFVSQGEVTVASIDDSEELLAT----DNAIDILGFSSEEKVGIYKLTGAV 358

Query: 831  YHLGAAGACKVGRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWG 890
             H G            M+F+      +A     E  + A +   L            R  
Sbjct: 359  MHYGN-----------MKFKQKQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVK 407

Query: 891  LEDEETSSGLKMTGV-DCVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGF 949
            + +E  + G  +  V + V  +A  +Y+++F  +V+ IN+   +       I V+D  GF
Sbjct: 408  VGNEYVTKGQNVQQVTNSVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGF 467

Query: 950  QNPRHQGKDRAATFEELCHNYAHERLQLLFYQRTFVSTLQRYQEEGVPVQFDLPDPSPGT 1009
            +           + E+LC N+ +E+LQ  F    FV   + Y++EG+  +F         
Sbjct: 468  EIFDFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAA 521

Query: 1010 TVAVVDQNPSQVRLPAGGGAQDARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTE 1069
             + ++++                 G+F +L+EE     ++D+    +L      K    +
Sbjct: 522  CIELIEK---------------PMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNNFQ 566

Query: 1070 GSSALRTCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSL 1129
                 +  +      + H  G   V Y++ GWL + K  L+  +    L+Q    +L S 
Sbjct: 567  KPKPAKG-KAEAHFSLVHYAG--TVDYNIAGWLDKNKDPLN--ETVVGLYQKSSLKLLSF 621

Query: 1130 FQARAKLPPVCRAVAGLEGTSQQALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMDALTS 1189
              +           AG E       ++    + +   +++AV R+         ++ L +
Sbjct: 622  LFSN---------YAGAETGDSGGSKKGGKKKGSSFQTVSAVFRE--------NLNKLMT 664

Query: 1190 MIKRSRLHFIHCLVPNPVVESRSGQESPPPPQPGRDKPGAGGPLALDIPALRVQLAGFHI 1249
             ++ +  HF+ CL+PN   E+++                   P  +D   +  QL    +
Sbjct: 665  NLRSTHPHFVRCLIPN---ETKT-------------------PGVMDHYLVMHQLRCNGV 702

Query: 1250 LEALRLHRTGYADHMGLTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLETLDLEKK 1309
            LE +R+ R G+   +    F++++++L+A  + +     + ID + A E+LL ++D++++
Sbjct: 703  LEGIRICRKGFPSRILYADFKQRYRILNASAIPE----GQFIDSKNASEKLLNSIDVDRE 758

Query: 1310 AVAVGHSQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQCI 1369
                G+++VF KAG++  LE+ R++ +   +   QA C+G+L R EFKK+  RR +  CI
Sbjct: 759  QFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTSTQAVCRGYLMRVEFKKMMERRDSIFCI 818

Query: 1370 QKNVAVFLAVKDWPWWQLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEKLRNELR 1429
            Q N+  F+ VK WPW  L   ++PLL +    +++   +E+    + +L +SE  R EL 
Sbjct: 819  QYNIRSFMNVKHWPWMNLFFKIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELE 878

Query: 1430 -------QNTDLLESKIADLTSDL--ADERFKGDVACQVL----ESERAERLQAFREV-Q 1475
                   Q  + L+ ++   T +L  A+ER +G +  ++L      E  ERL+   E+  
Sbjct: 879  EKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNS 938

Query: 1476 ELKSKHEQVQKKLGDVNKQLEEAQQKIQLNDLERNPTG------GADEWQMRFDCAQMEN 1529
            EL +K   ++ K   + + +++ +  +   + E++ T         +   +  + +++  
Sbjct: 939  ELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTK 998

Query: 1530 EFLRKRLQQC-----------EERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKC 1578
            E  +K LQ+            E++++  +    +LEQ+  +L+ + +  KK+   L+R  
Sbjct: 999  E--KKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAK 1056

Query: 1579 HHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVR 1638
              L  DL+ +   + + ++   ++E+K KK + +L+Q          L+ K+  E     
Sbjct: 1057 RKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQ----------LQAKIDDEQVHSL 1106

Query: 1639 WELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSAL 1698
                Q Q+++K+ +    +L++++E     + ++    S     +  + ERL +   +  
Sbjct: 1107 ----QFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATS 1162

Query: 1699 EQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDRED-------QEEELEDVRQSCQ 1751
             Q ++  ++E   +++ +  +   L+ E      +K + D       Q + L+ V+Q  +
Sbjct: 1163 AQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLE 1222

Query: 1752 KRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALL 1811
            K   +L+M+++      + +   K ++E    T+ DQ      +++ +  +  +  H L 
Sbjct: 1223 KEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFS----EIKAKDEQQTQLIHDL- 1277

Query: 1812 SDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENM 1871
             ++Q      ++G+ S   EE E + SQL           K+++ LT  LE +  ++E  
Sbjct: 1278 -NMQKARLQTQNGELSHRVEEKESLISQL----------TKSKQALTQQLEELKRQMEEE 1326

Query: 1872 TRNKSLVDEQLYRLQFEKADLLKRIDEDQD---DLNELMQKHKDLIAQ--SAADIGQIQE 1926
            T+ K+ +   L   + +   L ++ +E+Q+   +L   + K    +AQ  +  +   IQ 
Sbjct: 1327 TKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQR 1386

Query: 1927 LQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVD-----RAIVSRQEAVICDLENK--- 1978
             + +LEEAKK   KL ++LQ A+   E             + +    E ++ DLE     
Sbjct: 1387 TE-ELEEAKK---KLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTA 1442

Query: 1979 -TEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQYYQRRLEELKADMEE 2037
                 K Q + F+ ++   +  L +   EL +AA  ES+   +  +  R   E   D  E
Sbjct: 1443 CATLDKKQ-RNFDKVLAEWKQKLDESQAEL-EAAQKESRSLSTELFKMRNAYEEVVDQLE 1500

Query: 2038 LVQREAEASRRCMELEKYVEELAAVRQTLQTDLETS---IRRIADLQAALEEVASSDSDT 2094
             ++RE +  +   E+    E++A   + LQ   +T     +  +DLQ ALEEV  S    
Sbjct: 1501 TLRRENKNLQE--EISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHE 1558

Query: 2095 ESVQTAVDCGSSGRK------------EMDNVSILSSQPEGSLQSWLSCTLSLATDTMR 2141
            ES    V    S  K            E++ +   S +   +LQS L   +    D +R
Sbjct: 1559 ESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALR 1617



 Score =  124 bits (311), Expect = 1e-27
 Identities = 167/744 (22%), Positives = 322/744 (43%), Gaps = 109/744 (14%)

Query: 1409 EELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLAD-ERFKGDVACQVLESERAE- 1466
            E++  L+R  +K EK ++EL+   D + S I  L+   ++ ER      C+ +E + +E 
Sbjct: 1209 EQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIER-----TCRTVEDQFSEI 1263

Query: 1467 -------------------RLQA-----FREVQELKSKHEQVQKKLGDVNKQLEEAQQKI 1502
                               RLQ         V+E +S   Q+ K    + +QLEE ++++
Sbjct: 1264 KAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQM 1323

Query: 1503 QLNDLERNPTGGADEWQMRFDCAQMENEF-----LRKRLQQCEERLDSELT--------- 1548
            +     +N    A +   R DC  +  ++      +  LQ+   + +SE+          
Sbjct: 1324 EEETKAKNAMAHALQ-SSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETD 1382

Query: 1549 ----------ARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSR 1598
                      A+K+L Q+L E +   + A      L++    L  ++ED    LE   + 
Sbjct: 1383 AIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTA 1442

Query: 1599 NHELEKKQKKFDLQLA---QALGESVFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEA 1655
               L+KKQ+ FD  LA   Q L ES  E    E   +E+ S+  EL +++   ++   + 
Sbjct: 1443 CATLDKKQRNFDKVLAEWKQKLDESQAEL---EAAQKESRSLSTELFKMRNAYEEVVDQL 1499

Query: 1656 SQLKQQVEMLQDHKRELLGS-PSLGENCVAGLK-ERLWKLESSALEQQKIQSQQENTIKQ 1713
              L+++ + LQ+   +L       G+N     K ++L + E S L  Q    + E +++ 
Sbjct: 1500 ETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDL--QVALEEVEGSLEH 1557

Query: 1714 LEQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLH 1773
             E    R +LE+ ++K    +   +++EE+E ++++ Q+    L+  L+ E   +   L 
Sbjct: 1558 EESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALR 1617

Query: 1774 EKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQL----LLGTMEDGKTSVS 1829
             K+ +EG +  +  Q+GH +  + +  ++ LR     L D QL     L + ED K  ++
Sbjct: 1618 LKKKMEGDLNEMEIQLGHSNRQMAE-TQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLA 1676

Query: 1830 ---------KEELEKVHSQLEQSE---------------------AKCEEALKTQKVLTA 1859
                      EELE++   LEQ+E                     ++    + T+K L A
Sbjct: 1677 IVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEA 1736

Query: 1860 DLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAA 1919
            D+    +E+EN  +     +E+  +   + A + + + ++QD    L +  K+L  Q+  
Sbjct: 1737 DIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNL-EQTVK 1795

Query: 1920 DI-GQIQEL-QLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAI--VSRQEAVICDL 1975
            D+  ++ E  QL L+  KK+  KL+ +++  +  ++ +EQ     A+    + E  + ++
Sbjct: 1796 DLQHRLDEAEQLALKGGKKQIQKLENRVRELENELD-VEQKRGAEALKGAHKYERKVKEM 1854

Query: 1976 ENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQYYQRRLEEL--KA 2033
              + E     I R + LV +L+  +     +  +A    + Q    +  Q  LEE   +A
Sbjct: 1855 TYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERA 1914

Query: 2034 DMEELVQREAEASRRCMELEKYVE 2057
            D+ E    +  A  R +  +K  E
Sbjct: 1915 DIAESQVNKLRAKSRDVGSQKMEE 1938


>gi|215982794 myosin VA isoform 2 [Homo sapiens]
          Length = 1828

 Score =  232 bits (592), Expect = 3e-60
 Identities = 336/1556 (21%), Positives = 629/1556 (40%), Gaps = 224/1556 (14%)

Query: 559  EEHVHRANPPELDQVEDLASLISVNESSVLNTLLQRY-KAQLLHTCTGPDLIVLQPRGPS 617
            +E  H  NP  L    DL +L  ++E +VL+ L  R+  ++L++T  G  L+ + P    
Sbjct: 57   KELPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPY-EQ 115

Query: 618  VPSAGK----VPKGRRDG-LPAHIGSMAQRAYWALLNQRRDQSIVALGWSGAGKTTCCEQ 672
            +P  G+       G+  G +  HI ++A+ AY  +    R+QSI+  G SGAGKT   + 
Sbjct: 116  LPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKY 175

Query: 673  VLEHLVGMAGSVDGRVSVEKIRATFTVLRAFGSVSMAHSRSATRFSMVMSLDFNATGRIT 732
             + +   ++GS       EK+ A+  ++ + G+     + +++RF   + + F+   RI 
Sbjct: 176  AMRYFATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRII 235

Query: 733  AAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTELNLHQMADSSSFGMGVWSK 792
             A ++T LLEKSRV  Q E E N+ +F Q+ A   L     L L   AD+ ++     S 
Sbjct: 236  GANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGN-ADNFNYTKQGGSP 294

Query: 793  PEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAAG-------ACKVGRKQ 845
              +    A   A  + A  +LGISES Q  ++R+LA I HLG  G       +C +  K 
Sbjct: 295  VIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKH 354

Query: 846  FMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWGLEDEETSSGLKMTGV 905
                E      + +G +YEE+    +  H +      T+                K+   
Sbjct: 355  ----EPLCIFCDLMGVDYEEM--CHWLCHRKLATATETY-----------IKPISKLQAT 397

Query: 906  DCVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQGKDRAATFEE 965
            +  + +A  +Y +LF  +V  +N++  S     + I V+D  GF+           +FE+
Sbjct: 398  NARDALAKHIYAKLFNWIVDNVNQALHSAVKQHSFIGVLDIYGFET------FEINSFEQ 451

Query: 966  LCHNYAHERLQLLFYQRTFVSTLQRYQEEGVPVQFDLPDPSPGTTVAVVDQNPSQVRLPA 1025
             C NYA+E+LQ  F    F    + Y +E +          P T +   D  P  + L  
Sbjct: 452  FCINYANEKLQQQFNMHVFKLEQEEYMKEQI----------PWTLIDFYDNQPC-INL-- 498

Query: 1026 GGGAQDARGLFWVLDEEVHVEGSSDSVVLERL-------CAAFEKKGAGTEGSSALRTCE 1078
                +   G+  +LDEE  +   +D    ++L       CA FEK     +         
Sbjct: 499  ---IESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRLSNKA-------- 547

Query: 1079 QPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSLFQARAKLPP 1138
                     Q   D V Y   G+L + K  +   +  +VL  SK + L  LFQ   K   
Sbjct: 548  ------FIIQHFADKVEYQCEGFLEKNKDTVFE-EQIKVLKSSKFKMLPELFQDDEK--- 597

Query: 1139 VCRAVAGLEGTSQQALQRSRMVRRTF---ASSLAAVRRKAPCSQIKLQMDALTSMIKRSR 1195
               A++    TS      +R   +        +A   +K    Q +  +  L   +  + 
Sbjct: 598  ---AISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATT 654

Query: 1196 LHFIHCLVPNPVVESRSGQESPPPPQPGRDKPGAGGPLALDIPALRVQLAGFHILEALRL 1255
             H++ C+ PN                          P   D      QL    +LE +R+
Sbjct: 655  PHYVRCIKPNDF----------------------KFPFTFDEKRAVQQLRACGVLETIRI 692

Query: 1256 HRTGYADHMGLTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLETLDLEKKAVAVGH 1315
               G+        F  +++VL     K ++S     D ++  + +LE L L+K     G 
Sbjct: 693  SAAGFPSRWTYQEFFSRYRVLMKQ--KDVLS-----DRKQTCKNVLEKLILDKDKYQFGK 745

Query: 1316 SQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLK---------IRRLAA 1366
            +++F +AG ++ LEK R   +  + +  Q   +G+L R+++ +++         +R   A
Sbjct: 746  TKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQA 805

Query: 1367 QC----IQKNVAVFLAVKDWPWWQLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSE 1422
            +C    +++  A  +  K W  + +    +   +ATI           L +  R      
Sbjct: 806  RCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATI----------VLQSYLRGFLARN 855

Query: 1423 KLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESERAERLQAFREVQELK---- 1478
            + R  LR++  ++  K   +   LA   +K  +   +       R+ A RE+++LK    
Sbjct: 856  RYRKILREHKAVIIQK--RVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEAR 913

Query: 1479 -------------SKHEQVQKKLGDVNKQLEEAQQKI-QLNDLERNPTGGADEWQMRFDC 1524
                         +K  Q+Q+K+ + NK  +   +K+  L  +  + T        R   
Sbjct: 914  SVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQL 973

Query: 1525 AQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCD 1584
            ++ E +    R+   +E +      RK+LEQ   E +   + A +   + ++   +L   
Sbjct: 974  SEEEAKVATGRVLSLQEEI---AKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLK-- 1028

Query: 1585 LEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQL 1644
             E+  +L + +++ NH + ++ K+               + + +K+ +E   +  +L   
Sbjct: 1029 -EENTLLKQEKEALNHRIVQQAKE-------------MTETMEKKLVEETKQLELDLNDE 1074

Query: 1645 QQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGE---NCVAGLKERLWKLESSALEQQ 1701
            + + +    E S+L+++ + L++    ++  P  G    +      E  +   S   E +
Sbjct: 1075 RLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEME 1134

Query: 1702 KIQSQQENTIKQLEQL-------RQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRL 1754
             I S+ E   ++   L        Q+   E+E+ KQ+ Q + + +EE++  +R   ++  
Sbjct: 1135 DIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQV--LRSKAKEEE 1192

Query: 1755 HQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDV 1814
                   E EYE       ++Q+LE                  K+L+ +L      LS+ 
Sbjct: 1193 RPQIRGAELEYESL-----KRQELE---------------SENKKLKNELNELRKALSEK 1232

Query: 1815 QLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRN 1874
                 T         +  +E++ S  E+ + + EE L  +  L +  E++  + +  T  
Sbjct: 1233 SAPEVTAPG--APAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMT 1290

Query: 1875 KS---LVDEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADI-GQIQELQLQ 1930
             S   L D Q  + + E A     + E    L   +Q  K      A  + G+IQ L+  
Sbjct: 1291 DSTILLEDVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEALRGEIQSLK-- 1348

Query: 1931 LEEAKKEKHKLQEQLQV-AQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRF 1989
             EE  +++  L + LQ+  + RIE   Q  + R + +    ++  LE + +  +   K+ 
Sbjct: 1349 -EENNRQQQLLAQNLQLPPEARIEASLQHEITR-LTNENLDLMEQLEKQDKTVRKLKKQL 1406

Query: 1990 EVLVIRLRDSLIKMGEELSQAATSESQQR-----ESSQYYQRRLEELKADMEELVQ 2040
            +V   ++ +  +   E +S     +   R        + +Q  LE  K D ++LV+
Sbjct: 1407 KVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLEYKKEDEQKLVK 1462


>gi|215982791 myosin VA isoform 1 [Homo sapiens]
          Length = 1855

 Score =  229 bits (585), Expect = 2e-59
 Identities = 339/1571 (21%), Positives = 639/1571 (40%), Gaps = 227/1571 (14%)

Query: 559  EEHVHRANPPELDQVEDLASLISVNESSVLNTLLQRY-KAQLLHTCTGPDLIVLQPRGPS 617
            +E  H  NP  L    DL +L  ++E +VL+ L  R+  ++L++T  G  L+ + P    
Sbjct: 57   KELPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPY-EQ 115

Query: 618  VPSAGK----VPKGRRDG-LPAHIGSMAQRAYWALLNQRRDQSIVALGWSGAGKTTCCEQ 672
            +P  G+       G+  G +  HI ++A+ AY  +    R+QSI+  G SGAGKT   + 
Sbjct: 116  LPIYGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKY 175

Query: 673  VLEHLVGMAGSVDGRVSVEKIRATFTVLRAFGSVSMAHSRSATRFSMVMSLDFNATGRIT 732
             + +   ++GS       EK+ A+  ++ + G+     + +++RF   + + F+   RI 
Sbjct: 176  AMRYFATVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRII 235

Query: 733  AAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTELNLHQMADSSSFGMGVWSK 792
             A ++T LLEKSRV  Q E E N+ +F Q+ A   L     L L   AD+ ++     S 
Sbjct: 236  GANMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGN-ADNFNYTKQGGSP 294

Query: 793  PEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAAG-------ACKVGRKQ 845
              +    A   A  + A  +LGISES Q  ++R+LA I HLG  G       +C +  K 
Sbjct: 295  VIEGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKH 354

Query: 846  FMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWGLEDEETSSGLKMTGV 905
                E      + +G +YEE+    +  H +      T+                K+   
Sbjct: 355  ----EPLCIFCDLMGVDYEEM--CHWLCHRKLATATETY-----------IKPISKLQAT 397

Query: 906  DCVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQGKDRAATFEE 965
            +  + +A  +Y +LF  +V  +N++  S     + I V+D  GF+           +FE+
Sbjct: 398  NARDALAKHIYAKLFNWIVDNVNQALHSAVKQHSFIGVLDIYGFET------FEINSFEQ 451

Query: 966  LCHNYAHERLQLLFYQRTFVSTLQRYQEEGVPVQFDLPDPSPGTTVAVVDQNPSQVRLPA 1025
             C NYA+E+LQ  F    F    + Y +E +          P T +   D  P  + L  
Sbjct: 452  FCINYANEKLQQQFNMHVFKLEQEEYMKEQI----------PWTLIDFYDNQPC-INL-- 498

Query: 1026 GGGAQDARGLFWVLDEEVHVEGSSDSVVLERL-------CAAFEKKGAGTEGSSALRTCE 1078
                +   G+  +LDEE  +   +D    ++L       CA FEK     +         
Sbjct: 499  ---IESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEKPRLSNKA-------- 547

Query: 1079 QPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSLFQARAKLPP 1138
                     Q   D V Y   G+L + K  +   +  +VL  SK + L  LFQ   K   
Sbjct: 548  ------FIIQHFADKVEYQCEGFLEKNKDTVFE-EQIKVLKSSKFKMLPELFQDDEK--- 597

Query: 1139 VCRAVAGLEGTSQQALQRSRMVRRTF---ASSLAAVRRKAPCSQIKLQMDALTSMIKRSR 1195
               A++    TS      +R   +        +A   +K    Q +  +  L   +  + 
Sbjct: 598  ---AISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATT 654

Query: 1196 LHFIHCLVPNPVVESRSGQESPPPPQPGRDKPGAGGPLALDIPALRVQLAGFHILEALRL 1255
             H++ C+ PN                          P   D      QL    +LE +R+
Sbjct: 655  PHYVRCIKPNDF----------------------KFPFTFDEKRAVQQLRACGVLETIRI 692

Query: 1256 HRTGYADHMGLTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLETLDLEKKAVAVGH 1315
               G+        F  +++VL     K ++S     D ++  + +LE L L+K     G 
Sbjct: 693  SAAGFPSRWTYQEFFSRYRVLMKQ--KDVLS-----DRKQTCKNVLEKLILDKDKYQFGK 745

Query: 1316 SQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLK---------IRRLAA 1366
            +++F +AG ++ LEK R   +  + +  Q   +G+L R+++ +++         +R   A
Sbjct: 746  TKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQA 805

Query: 1367 QC----IQKNVAVFLAVKDWPWWQLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSE 1422
            +C    +++  A  +  K W  + +    +   +ATI           L +  R      
Sbjct: 806  RCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATI----------VLQSYLRGFLARN 855

Query: 1423 KLRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESERAERLQAFREVQELK---- 1478
            + R  LR++  ++  K   +   LA   +K  +   +       R+ A RE+++LK    
Sbjct: 856  RYRKILREHKAVIIQK--RVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEAR 913

Query: 1479 -------------SKHEQVQKKLGDVNKQLEEAQQKI-QLNDLERNPTGGADEWQMRFDC 1524
                         +K  Q+Q+K+ + NK  +   +K+  L  +  + T        R   
Sbjct: 914  SVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQL 973

Query: 1525 AQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCD 1584
            ++ E +    R+   +E +      RK+LEQ   E +   + A +   + ++   +L   
Sbjct: 974  SEEEAKVATGRVLSLQEEI---AKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLK-- 1028

Query: 1585 LEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQL 1644
             E+  +L + +++ NH + ++ K+               + + +K+ +E   +  +L   
Sbjct: 1029 -EENTLLKQEKEALNHRIVQQAKE-------------MTETMEKKLVEETKQLELDLNDE 1074

Query: 1645 QQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGE---NCVAGLKERLWKLESSALEQQ 1701
            + + +    E S+L+++ + L++    ++  P  G    +      E  +   S   E +
Sbjct: 1075 RLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEME 1134

Query: 1702 KIQSQQENTIKQLEQL-------RQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRL 1754
             I S+ E   ++   L        Q+   E+E+ KQ+ Q + + +EE++  +R   ++  
Sbjct: 1135 DIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQV--LRSKAKEEE 1192

Query: 1755 HQLEMQLEQEYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDV 1814
                   E EYE       ++Q+LE     L +++      + ++   ++    A    V
Sbjct: 1193 RPQIRGAELEYESL-----KRQELESENKKLKNELNELRKALSEKSAPEVTAPGAPAYRV 1247

Query: 1815 QLLLGTMEDGKTSVSKEELEKVHSQL-EQSEA----KCEEALKTQKVLTADLESMHSE-- 1867
             +   T    +  V KEE+  + SQL  Q EA      +  +    +L  D++ M  +  
Sbjct: 1248 LMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGE 1307

Query: 1868 -------LENMTRNKSLVDEQLYR-----LQFEKADLLKRIDEDQDDLNELMQKHKDLIA 1915
                   L+   R+ +L   +L       L +E      R+ E Q  L    + H++   
Sbjct: 1308 IAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANRLLESQ--LQSQKRSHEN--- 1362

Query: 1916 QSAADIGQIQELQLQLEEAKKEKHKLQEQLQV-AQMRIEYLEQSTVDRAIVSRQEAVICD 1974
            ++ A  G+IQ L+   EE  +++  L + LQ+  + RIE   Q  + R + +    ++  
Sbjct: 1363 EAEALRGEIQSLK---EENNRQQQLLAQNLQLPPEARIEASLQHEITR-LTNENLDLMEQ 1418

Query: 1975 LENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQR-----ESSQYYQRRLE 2029
            LE + +  +   K+ +V   ++ +  +   E +S     +   R        + +Q  LE
Sbjct: 1419 LEKQDKTVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDEPIRPVNIPRKEKDFQGMLE 1478

Query: 2030 ELKADMEELVQ 2040
              K D ++LV+
Sbjct: 1479 YKKEDEQKLVK 1489


>gi|153945715 myosin VC [Homo sapiens]
          Length = 1742

 Score =  219 bits (559), Expect = 2e-56
 Identities = 324/1502 (21%), Positives = 613/1502 (40%), Gaps = 214/1502 (14%)

Query: 566  NPPELDQVEDLASLISVNESSVLNTLLQRY-KAQLLHTCTGPDLIVLQPRGPSVPSAGKV 624
            NP  L    DL +L  ++E +VL+ L  R+ +++L++T +G  L+ + P    +P  G  
Sbjct: 62   NPDILVGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPY-KQLPIYGDA 120

Query: 625  P----KGRRDG-LPAHIGSMAQRAYWALLNQRRDQSIVALGWSGAGKTTCCEQVLEHLVG 679
                  G+  G +  HI ++A+ AY  +    R+QSI+  G SGAGKT      + +   
Sbjct: 121  IIHAYSGQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFAT 180

Query: 680  MAGSVDGRVSVEKIRATFTVLRAFGSVSMAHSRSATRFSMVMSLDFNATGRITAAQLQTM 739
            ++ S       +K+ A+  +  A G+     + +++RF     + F+   +I  A + T 
Sbjct: 181  VSKSGSNAHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTY 240

Query: 740  LLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTELNLHQMADSSSFGMGVWSKPEDKQKA 799
            LLEKSRV  Q E E N+ +F Q+ A         L L    + +   MG  +  E     
Sbjct: 241  LLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVNDR 300

Query: 800  AAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAAGACKVGRKQFMRFEWANYAAEAL 859
            A    + Q    +LG  E  Q  V+++LAAI HLG      VG ++    E  ++    +
Sbjct: 301  AE-MVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLK--V 357

Query: 860  GCEYEELNTATFKHHL--RQIIQQMTFGPSRWGLEDEETSSGLKMTGVDCVEGMASGLYQ 917
             CE   L +      L  R+I+             +       +   V+  + +A  +Y 
Sbjct: 358  FCELLGLESGRVAQWLCNRKIVTS----------SETVVKPMTRPQAVNARDALAKKIYA 407

Query: 918  ELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQGKDRAATFEELCHNYAHERLQL 977
             LF  +V  IN++          I V+D  GF+           +FE+ C NYA+E+LQ 
Sbjct: 408  HLFDFIVERINQALQFSGKQHTFIGVLDIYGFET------FDVNSFEQFCINYANEKLQQ 461

Query: 978  LFYQRTFVSTLQRYQEEGVP-VQFDLPDPSPGTTVAVVDQNPSQVRLPAGGGAQDARGLF 1036
             F    F    + Y +E +P    D  D  P     V+D   +++            G+ 
Sbjct: 462  QFNMHVFKLEQEEYMKEDIPWTLIDFYDNQP-----VIDLIEAKM------------GIL 504

Query: 1037 WVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTEGSSALRTCEQPLQCEIFHQLGWDPVRY 1096
             +LDEE  +   +D   L++L   F  +    E      T           Q   D V Y
Sbjct: 505  ELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKPRMSNT-------SFVIQHFADKVEY 557

Query: 1097 DLTGWLHRAKPNLSALDAPQVLHQSKREELRSLFQARAKLPPVCRAVAGLEGTSQQALQR 1156
               G+L + +  +  +   ++L  SK     + FQ     P    ++  ++   Q     
Sbjct: 558  KCEGFLEKNRDTVYDM-LVEILRASKFHLCANFFQENPTPPSPFGSMITVKSAKQVIKPN 616

Query: 1157 SRMVRRTFASSLAAVRRKAPCSQIKLQMDALTSMIKRSRLHFIHCLVPNPVVESRSGQES 1216
            S+  R T  S           S + L M+ L +       H++ C+ PN           
Sbjct: 617  SKHFRTTVGSKFR--------SSLYLLMETLNATTP----HYVRCIKPNDEKL------- 657

Query: 1217 PPPPQPGRDKPGAGGPLALDIPALRVQLAGFHILEALRLHRTGYADHMGLTRFRRQFQVL 1276
                           P   D   +  QL    +LE +R+    Y        F  ++ +L
Sbjct: 658  ---------------PFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGIL 702

Query: 1277 DAPLLKKLMSTSEGIDERKAVEELLETLDLEKKAVAVGHSQVFLKAGVISRLEKQREKLV 1336
               + K+ +S S   D+++  + +L  L  +      G +++F +AG ++ LEK R   +
Sbjct: 703  ---MTKQELSFS---DKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKL 756

Query: 1337 SQSIVLFQAACKGFLSRQEFKKLKIRRLA---------AQCIQKNVAVFLAVKDWPWWQL 1387
             QS V+ Q   +G+L R++F  L+ RR A          Q ++K +      + W    +
Sbjct: 757  RQSCVMVQKHMRGWLQRKKF--LRERRAALIIQQYFRGQQTVRKAITAVALKEAWAAIII 814

Query: 1388 LGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLA 1447
                +  L  ++  + +R     +    R      + R  L ++  ++  K A   + LA
Sbjct: 815  QKHCRGYLVRSL-YQLIRMATITMQAYSRGFLARRRYRKMLEEHKAVILQKYA--RAWLA 871

Query: 1448 DERFKGDVACQVLESERAERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQKIQLNDL 1507
              RF              + ++ F    +L  + +++QKKL D NK+     +K  L  L
Sbjct: 872  RRRF--------------QSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEK--LTSL 915

Query: 1508 ERNPTGGADEWQMRFDCAQMENEFLRKRLQQCEERLDSELTARKELEQKLGELQSAYDGA 1567
                 G  +                  ++Q+ E  L+   T R+  E+K    + A +  
Sbjct: 916  AALRAGDVE------------------KIQKLEAELEKAATHRRNYEEKGKRYRDAVE-- 955

Query: 1568 KKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFDLQLAQALGESVFEKGLR 1627
            +K+A   K + H+   + +   + L+ Q+ +  EL++K      QL   + +   ++ L 
Sbjct: 956  EKLA---KLQKHNSELETQKEQIQLKLQE-KTEELKEKMDNLTKQLFDDVQKEERQRMLL 1011

Query: 1628 EKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGSPSLGENCVA-GL 1686
            EK               + + +  E++   LK++++ L+D K +L      GE+  + GL
Sbjct: 1012 EK-------------SFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVE-GEHVTSDGL 1057

Query: 1687 KERLWKLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELEDV 1746
            K  + +L           S+Q  TI +       FE EIE +    Q  + D E+ ++  
Sbjct: 1058 KAEVARL-----------SKQVKTISE-------FEKEIELL----QAQKIDVEKHVQSQ 1095

Query: 1747 RQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGTL-CDQIGHRDFDVEKRLRRDLR 1805
            ++  ++++ ++  QL + Y           D+E +   L  + + H + D E      L 
Sbjct: 1096 KREMREKMSEITKQLLESY-----------DIEDVRSRLSVEDLEHLNEDGE------LW 1138

Query: 1806 RTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESMH 1865
              +  L     +L +    +    ++E+E ++ ++     +     K  +      ES+ 
Sbjct: 1139 FAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESIR 1198

Query: 1866 SELENMTRNKSLV---DEQLYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADIG 1922
             E+  +T    ++    +Q+  L+ +K DL  R++E  + +   +++  + + +S  + G
Sbjct: 1199 HEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQEEEG 1258

Query: 1923 -QIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQSTVDRAIVS---RQEAVICDLENK 1978
             Q + L+ Q E   KEK KL +++Q  Q   ++L++     + V    RQEA    LEN+
Sbjct: 1259 TQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENR 1318

Query: 1979 TEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQYYQRRLEELKADMEEL 2038
               +++ +K  + ++ +L+D +  + + + +A  ++       + Y   L+  + D  +L
Sbjct: 1319 DLEEELDMK--DRVIKKLQDQVKTLSKTIGKA--NDVHSSSGPKEYLGMLQYKREDEAKL 1374

Query: 2039 VQ 2040
            +Q
Sbjct: 1375 IQ 1376



 Score = 38.5 bits (88), Expect = 0.086
 Identities = 44/178 (24%), Positives = 77/178 (43%), Gaps = 20/178 (11%)

Query: 1923 QIQELQLQLEEAKKEKHKLQEQL-QVAQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEF 1981
            ++Q LQ +LE+  KE H L E+L  +A +R   +E+              I  LE + E 
Sbjct: 890  RVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEK--------------IQKLEAELEK 935

Query: 1982 QKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRESSQY-YQRRLEELKADMEELVQ 2040
                 + +E    R RD++ +   +L +  +    Q+E  Q   Q + EELK  M+ L +
Sbjct: 936  AATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTK 995

Query: 2041 R----EAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIADLQAALEEVASSDSDT 2094
            +      +  R+ M LEK  E      +     L+  I+ + D +  L+ +   +  T
Sbjct: 996  QLFDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVT 1053


>gi|122937345 myosin VB [Homo sapiens]
          Length = 1848

 Score =  214 bits (544), Expect = 1e-54
 Identities = 338/1617 (20%), Positives = 654/1617 (40%), Gaps = 240/1617 (14%)

Query: 512  EAEKVWLAQKDGFTLATVLKPD--EGTADLPAGRVRLWIDADKTITEVDEEHVHR----- 564
            +  +VW+   D    +  L  D  EG   L   ++RL    D+TI E   + V R     
Sbjct: 9    QCTRVWIPDPDEVWRSAELTKDYKEGDKSL---QLRL---EDETILEYPID-VQRNQLPF 61

Query: 565  -ANPPELDQVEDLASLISVNESSVLNTLLQRY-KAQLLHTCTGPDLIVLQPRGPSVPSAG 622
              NP  L    DL +L  ++E +VL+ L  R+ ++  ++T  G  L+ + P    +P  G
Sbjct: 62   LRNPDILVGENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPY-EQLPIYG 120

Query: 623  K----VPKGRRDG-LPAHIGSMAQRAYWALLNQRRDQSIVALGWSGAGKTTCCEQVLEHL 677
            +       G+  G +  HI ++A+ AY  +    ++QSI+  G SGAGKT   +  + + 
Sbjct: 121  QDVIYTYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYF 180

Query: 678  VGMAGSVDGRVSVEKIRATFTVLRAFGSVSMAHSRSATRFSMVMSLDFNATGRITAAQLQ 737
              + GS       EK+ A+  ++ A G+     + +++RF   + + F+    I  A ++
Sbjct: 181  ATVGGSASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMR 240

Query: 738  TMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTELNLHQMADSSSFGMGVWSKPEDKQ 797
            T LLEKSRV  Q + E N+ +F Q+ A   L    EL L    D      G  +  E   
Sbjct: 241  TYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVD 300

Query: 798  KAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAAG--------ACKVGRKQFMRF 849
              A  F + + A  +LG+ ES Q ++++++A+I HLG+          +C +  +     
Sbjct: 301  D-AEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDV--- 356

Query: 850  EWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWGLEDEETSSGLKMTGVDCVE 909
             + +     LG E+ ++    +  H + +    T+          +T S  ++  ++   
Sbjct: 357  -YLSNFCRLLGVEHSQME--HWLCHRKLVTTSETY---------VKTMSLQQV--INARN 402

Query: 910  GMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQGKDRAATFEELCHN 969
             +A  +Y +LF  +V  IN++  +     + I V+D  GF+           +FE+ C N
Sbjct: 403  ALAKHIYAQLFGWIVEHINKALHTSLKQHSFIGVLDIYGFET------FEVNSFEQFCIN 456

Query: 970  YAHERLQLLFYQRTFVSTLQRYQEEGVPVQFDLPDPSPGTTVAVVDQNPSQVRLPAGGGA 1029
            YA+E+LQ  F    F    + Y +E +          P T +   D  P    + A  G 
Sbjct: 457  YANEKLQQQFNSHVFKLEQEEYMKEQI----------PWTLIDFYDNQPCIDLIEAKLGI 506

Query: 1030 QDARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTEGSSALRTCEQPLQCE----I 1085
             D      +LDEE  V   +D    ++L           +  S+ +  ++P        I
Sbjct: 507  LD------LLDEECKVPKGTDQNWAQKL----------YDRHSSSQHFQKPRMSNTAFII 550

Query: 1086 FHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSLFQARAKLPPVCRAVAG 1145
             H    D V Y   G+L + +  +   +   +L  SK   +  LF       PV     G
Sbjct: 551  VHFA--DKVEYLSDGFLEKNRDTVYE-EQINILKASKFPLVADLF--HDDKDPVPATTPG 605

Query: 1146 LEGTSQQALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMDALTSMIKRSRLHFIHCLVPN 1205
               +S+ +++ +R   +          +K    Q +  +  L   +  +  H++ C+ PN
Sbjct: 606  KGSSSKISVRSARPPMKVSNKE----HKKTVGHQFRTSLHLLMETLNATTPHYVRCIKPN 661

Query: 1206 PVVESRSGQESPPPPQPGRDKPGAGGPLALDIPALRVQLAGFHILEALRLHRTGYADHMG 1265
                                      P   D      QL    +LE +R+   GY     
Sbjct: 662  ----------------------DEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWA 699

Query: 1266 LTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLETLDLEKKAVAVGHSQVFLKAGVI 1325
               F  +++VL     ++L +T    D++     +LE L  +      G +++F +AG +
Sbjct: 700  YHDFFNRYRVLVKK--RELANT----DKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQV 753

Query: 1326 SRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLK--------------IRRLAAQCIQK 1371
            + LEK R      + ++ Q   +G+L + ++ +LK               RRLA    + 
Sbjct: 754  AYLEKLRADKFRTATIMIQKTVRGWLQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRI 813

Query: 1372 NVAVFLAVKDWPWWQLLGSLQPLLSATIGTEQLRAKEEELTTLRRKL--EKSEKLRNEL- 1428
              AV L  K +   +   + Q +  A +  +          T R+ L   K+  ++  + 
Sbjct: 814  RAAVVLQ-KHYRMQRARQAYQRVRRAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVR 872

Query: 1429 ----RQNTDLLESKIADLTSDLADERFKGDVACQVLESERAERLQAFREVQELKSKHEQV 1484
                R++   L      +       + + ++    +E+  AE L+      E  +K  Q+
Sbjct: 873  GWMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEHLKRLNVGME--NKVVQL 930

Query: 1485 QKKLGDVNKQLEEAQQKIQLNDLERNPTGGADEWQMRFDCAQMENEFLRKRLQQCEER-- 1542
            Q+K+ + NK+ +   +++ +                      ME E L+K L   ++   
Sbjct: 931  QRKIDEQNKEFKTLSEQLSVTT----------------STYTMEVERLKKELVHYQQSPG 974

Query: 1543 LDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHL---TCDLEDTCVLL--ENQQS 1597
             D+ L  ++E+E    ELQ A+   K +     R+   L     DLE    LL  E +Q 
Sbjct: 975  EDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQL 1034

Query: 1598 RNHELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEASQ 1657
             N  L + + +F      ++ E++ +K L E+ ++    V+ E  QL+Q+      E + 
Sbjct: 1035 NNQILCQSKDEF---AQNSVKENLMKKELEEERSRYQNLVK-EYSQLEQRYDNLRDEMTI 1090

Query: 1658 LKQQVEMLQDHKRELLGS---------PSLGENCVAGLKERLWKLESSALEQQKIQS--- 1705
            +KQ       H+R              PS+  + +   ++ L ++E   LE+  +     
Sbjct: 1091 IKQ----TPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVF 1146

Query: 1706 -QQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELE-DVRQSCQKRLHQLEMQLEQ 1763
             + +  +++LEQ R++ ++++E+ +Q   K  + +  + + D+  +     + L+ Q E 
Sbjct: 1147 LKLQKRVRELEQERKKLQVQLEKREQQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQ-EL 1205

Query: 1764 EYEEKQMVLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTME- 1822
            E E K++    K DL  L   + DQ    +             +H       LLL  ++ 
Sbjct: 1206 ESENKKL----KNDLNELRKAVADQATQNN------------SSHGSPDSYSLLLNQLKL 1249

Query: 1823 -DGKTSVSKEELEKVHSQLEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQ 1881
               +  V KEE+  + +Q+  ++ +        ++   + E   +   +   ++  VD++
Sbjct: 1250 AHEELEVRKEEVLILRTQIVSADQR--------RLAGRNAEPNINARSSWPNSEKHVDQE 1301

Query: 1882 LYRLQFEKADLLKRIDEDQDDLNELMQKHKDLIAQSAADIGQIQELQLQLE--EAKKEKH 1939
                 +          ED   LNE       L  Q    + ++ E QLQ +  E ++E  
Sbjct: 1302 DAIEAYHGVCQTNSKTEDWGYLNE--DGELGLAYQGLKQVARLLEAQLQAQSLEHEEEVE 1359

Query: 1940 KLQEQLQVAQMRIEYLEQSTVDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDS 1999
             L+ QL+  +  ++  +Q+     ++S +  V   ++ +              + RL + 
Sbjct: 1360 HLKAQLEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQE--------------ISRLTNE 1405

Query: 2000 LIKMGEELSQAATSESQQRESSQYYQRRLEELKADMEELVQREAEASRRCMELEKYV 2056
             + + E + +   +E + ++  + Y ++ ++L+A      Q  A++ R+  EL + V
Sbjct: 1406 NLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEA-----AQALAQSERKRHELNRQV 1457



 Score = 65.1 bits (157), Expect = 9e-10
 Identities = 138/704 (19%), Positives = 293/704 (41%), Gaps = 101/704 (14%)

Query: 1317 QVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKNVAVF 1376
            Q F +A  + R    R+ L+       Q   +G+++R+ F++L+   +  QC  + +   
Sbjct: 843  QAFTRAMFVRRT--YRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRML--- 897

Query: 1377 LAVKDWPWWQLLGSLQPLLSATIGTEQLR----AKEEELTTLRRKLEKSEKLRNELRQNT 1432
                     +    L+ L       E L+      E ++  L+RK+++  K    L +  
Sbjct: 898  ---------KARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQL 948

Query: 1433 DLLESKIADLTSDLADERFKGDVACQVLESERAERLQAFREVQELKSKHEQV--QKKLGD 1490
             +  S     T  +  ER K ++            L+   EV+ L+++ ++   ++K+ +
Sbjct: 949  SVTTS-----TYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILE 1003

Query: 1491 VNKQLEEAQQKIQLNDLERNPTGGADEWQMRFDCAQMENEFLRKRLQQCEERLDSELTAR 1550
                 E+ + + ++ DLE+      DE +      Q+ N+ L +   +  +    E   +
Sbjct: 1004 DAHSREKDELRKRVADLEQENALLKDEKE------QLNNQILCQSKDEFAQNSVKENLMK 1057

Query: 1551 KELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRNHELEKKQKKFD 1610
            KELE++    +S Y    K   QL+++  +L    ++  ++ +    R +   +   + D
Sbjct: 1058 KELEEE----RSRYQNLVKEYSQLEQRYDNLR---DEMTIIKQTPGHRRNPSNQSSLESD 1110

Query: 1611 LQLAQALGESVFEKGLREKVTQENTSVRWELG--------QLQQQLKQKEQEASQLKQQV 1662
                     S  E G  E   Q+   +  E          +LQ+++++ EQE  +L+ Q+
Sbjct: 1111 SNYPSI---STSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQERKKLQVQL 1167

Query: 1663 EM--LQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQR 1720
            E    QD K+     P    +           L  ++L++Q+++S+ +     L +LR+ 
Sbjct: 1168 EKREQQDSKKVQAEPPQTDIDLDPNA-----DLAYNSLKRQELESENKKLKNDLNELRKA 1222

Query: 1721 FELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQLEM---QLEQEYEE-----KQMVL 1772
                          D+  Q         S    L+QL++   +LE   EE      Q+V 
Sbjct: 1223 V------------ADQATQNNSSHGSPDSYSLLLNQLKLAHEELEVRKEEVLILRTQIVS 1270

Query: 1773 HEKQDLEG--------LIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDG 1824
             +++ L G           +  +   H D +        + +T++   D   L    EDG
Sbjct: 1271 ADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNSKTEDWGYL---NEDG 1327

Query: 1825 KTSVSKEELEKVHSQLE-QSEAKCEEALKTQKVLTADLESMHSELENMTRN--KSLVDEQ 1881
            +  ++ + L++V   LE Q +A+  E  +  + L A LE++  E++   +   ++L+   
Sbjct: 1328 ELGLAYQGLKQVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLLLSP 1387

Query: 1882 LYRLQFEKADLLKRIDEDQDDLNELMQK----HKDLIAQSAADIGQIQELQL--QLEEAK 1935
              +++F     + R+  +  DL EL++K     + L  Q    + + Q+L+    L +++
Sbjct: 1388 EAQVEFGVQQEISRLTNENLDLKELVEKLEKNERKLKKQLKIYMKKAQDLEAAQALAQSE 1447

Query: 1936 KEKHKLQEQLQVAQMRIEY---LEQSTVDRAIVSRQEAVICDLE 1976
            +++H+L  Q+ V +   ++   LE    D A++ R   ++ DL+
Sbjct: 1448 RKRHELNRQVTVQRKEKDFQGMLEYHKEDEALLIRN--LVTDLK 1489


>gi|154354979 myosin X [Homo sapiens]
          Length = 2058

 Score =  209 bits (531), Expect = 4e-53
 Identities = 264/1064 (24%), Positives = 449/1064 (42%), Gaps = 161/1064 (15%)

Query: 512  EAEKVWLAQKDGFTLATVLKPDEGTADLPAGRVRLWIDADKTITEVDEEHVHRANPPELD 571
            E  +VWL +      +TV    EG         +++     TIT    + V   +P   +
Sbjct: 7    EGTRVWLRENGQHFPSTVNSCAEGIVVFRTDYGQVFTYKQSTITH---QKVTAMHPTNEE 63

Query: 572  QVEDLASLISVNESSVLNTLLQRYKAQLLHTCTGPDLIVLQPRGPSV----PSAGKVPKG 627
             V+D+ASL  ++  S++  L QRYK   ++T  G  L  + P  P      P+  +    
Sbjct: 64   GVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQYSR 123

Query: 628  RRDG-LPAHIGSMAQRAYWALLNQRRDQSIVALGWSGAGKTTCCEQVLEHLVGMAG---- 682
            R  G LP HI ++A   Y  L  +  +Q I+  G SGAGKT   + +L+ L  ++     
Sbjct: 124  RHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQSLE 183

Query: 683  -SVDGRVS-VEK-IRATFTVLRAFGSVSMAHSRSATRFSMVMSLDFNATGRITAAQLQTM 739
             S+  + S VE+ I  +  ++ AFG+    ++ +++RF   + L+    G I   ++   
Sbjct: 184  LSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIVDY 243

Query: 740  LLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTEL------NLHQMADSSSFGMGVWSKP 793
            LLEK+RV RQ  GE N+ +F  +LAGL+ + R E       N H +  S           
Sbjct: 244  LLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCV-------- 295

Query: 794  EDKQ-KAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAAGACKVGRKQFMRFEWA 852
            EDK      +F ++  AM+++  S+ E R V R+LA I HLG       G  Q       
Sbjct: 296  EDKTISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFITAGGAQVSFKTAL 355

Query: 853  NYAAEALGCEYEELNTATFKHHLRQIIQQMTFGPSRWGLEDEETSSGLKM-TGVDCVEGM 911
              +AE LG +  +L  A        + Q+  F      L  EE  + L +   VD  + +
Sbjct: 356  GRSAELLGLDPTQLTDA--------LTQRSMF------LRGEEILTPLNVQQAVDSRDSL 401

Query: 912  ASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQNPRHQGKDRAATFEELCHNYA 971
            A  LY   F  V+  IN     +     SI ++D  GF+N           FE+   NYA
Sbjct: 402  AMALYACCFEWVIKKINSRIKGNE-DFKSIGILDIFGFEN------FEVNHFEQFNINYA 454

Query: 972  HERLQLLFYQRTFVSTLQRYQEEGVPVQFDLPDPSPGTTVAVVDQNPSQVRLPAGGGAQD 1031
            +E+LQ  F +  F      Y  EG+ V  D+     G  + ++++               
Sbjct: 455  NEKLQEYFNKHIFSLEQLEYSREGL-VWEDIDWIDNGECLDLIEKK-------------- 499

Query: 1032 ARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTEGSSALRTCEQPLQCEIFHQLGW 1091
              GL  +++EE H   ++DS +LE+L +         +   A+          + H  G 
Sbjct: 500  -LGLLALINEESHFPQATDSTLLEKLHSQHANNHFYVKPRVAVN------NFGVKHYAG- 551

Query: 1092 DPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSLFQARAKLPPVCRAVAGLEGTSQ 1151
              V+YD+ G L + +      D   +L +S+ + +  LF+  +               +Q
Sbjct: 552  -EVQYDVRGILEKNRDTFRD-DLLNLLRESRFDFIYDLFEHVS------------SRNNQ 597

Query: 1152 QALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMDALTSMIKRSRLHFIHCLVPNPVVESR 1211
              L+     RR   S           SQ K  + +L + +  S   F+ C+ PN      
Sbjct: 598  DTLKCGSKHRRPTVS-----------SQFKDSLHSLMATLSSSNPFFVRCIKPNM----- 641

Query: 1212 SGQESPPPPQPGRDKPGAGGPLALDIPALRVQLAGFHILEALRLHRTGYADHMGLTRFRR 1271
              Q+ P                  D   +  QL    +LE +R+ + GYA       F +
Sbjct: 642  --QKMPD---------------QFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYK 684

Query: 1272 QFQVLDAPLLKKLMSTSEGIDERKAVEELLETLDLEKKAVAVGHSQVFLKAGVISRLEKQ 1331
            +++VL       + + +   D R     LL+  D       +G ++VFL+  +  +LEK+
Sbjct: 685  RYKVL-------MRNLALPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKR 737

Query: 1332 REKLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKNVAVFLAVKDWPWWQLLGSL 1391
            RE+ VS + ++ +A   GFL+R++++K+         IQKN   FL  + +        L
Sbjct: 738  REEEVSHAAMVIRAHVLGFLARKQYRKV---LYCVVIIQKNYRAFLLRRRF--------L 786

Query: 1392 QPLLSATIGTEQLR---AKEEELTTLRRKLEKSEKLRNELRQNTDLLESKIADLTSDLAD 1448
                +A +  +QLR   A+      L  K E+ EK + E  +     + K  +   +   
Sbjct: 787  HLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEE-----KKKREEEERERER 841

Query: 1449 ERFKGDVACQVLESERAERLQAFREVQELKSKHEQVQKKLGDVNKQLEEAQQKIQLNDLE 1508
            ER + ++        RA++ +  R+ QEL++   Q  +K  ++ ++LE+ ++  Q+ ++ 
Sbjct: 842  ERREAEL--------RAQQEEETRKQQELEAL--QKSQKEAELTRELEKQKENKQVEEIL 891

Query: 1509 RNPTGGADEWQMRFDCAQMENEFLRKRLQQCEERLDSELTARKE 1552
            R      D  +M+    Q E       LQ+ +ER D EL   +E
Sbjct: 892  RLEKEIEDLQRMK---EQQELSLTEASLQKLQERRDQELRRLEE 932



 Score = 35.8 bits (81), Expect = 0.56
 Identities = 49/271 (18%), Positives = 123/271 (45%), Gaps = 20/271 (7%)

Query: 1616 ALGESVFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEASQLKQQVEMLQDHKRELLGS 1675
            AL E V  K        + ++  W+LG+ +  L++  ++  + +++ E+   H   ++ +
Sbjct: 694  ALPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEV--SHAAMVIRA 751

Query: 1676 PSLGENCVAGLKERLW------KLESSALEQQKIQSQQENTIKQLEQLRQRFELEIERM- 1728
              LG       ++ L+      K   + L +++    ++  I   +QLR +    + R  
Sbjct: 752  HVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQL 811

Query: 1729 ----KQMHQKDREDQEEELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLEGLIGT 1784
                ++  +K ++++EE+ +   +  ++   + E +L  + EE+     ++Q+LE L  +
Sbjct: 812  LAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE---TRKQQELEALQKS 868

Query: 1785 LCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQLEQSE 1844
              +    R+ + +K   + +     L  +++ L    E  + S+++  L+K+  + +Q  
Sbjct: 869  QKEAELTRELEKQKE-NKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQEL 927

Query: 1845 AKCEEALKTQKVLTADLESMH-SELENMTRN 1874
             + EE  +  +     LES++  E++   RN
Sbjct: 928  RRLEE--EACRAAQEFLESLNFDEIDECVRN 956



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 40/192 (20%), Positives = 89/192 (46%), Gaps = 23/192 (11%)

Query: 1699 EQQKIQSQQENTIKQLEQLRQRFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQLE 1758
            EQ++ + Q+E   K+ E+  +  E E    +   Q++ E ++++  +  Q  QK   +L 
Sbjct: 817  EQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEA-ELT 875

Query: 1759 MQLEQEYEEKQM--VLHEKQDLEGLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQ- 1815
             +LE++ E KQ+  +L  ++++E L                 + +++L  T A L  +Q 
Sbjct: 876  RELEKQKENKQVEEILRLEKEIEDL--------------QRMKEQQELSLTEASLQKLQE 921

Query: 1816 ---LLLGTMEDGKTSVSKEELEKVH-SQLEQSEAKCEEALKTQKVLTADL-ESMHSELEN 1870
                 L  +E+     ++E LE ++  ++++     E +L      +++L ES   E  N
Sbjct: 922  RRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAESACEEKPN 981

Query: 1871 MTRNKSLVDEQL 1882
               ++   +E++
Sbjct: 982  FNFSQPYPEEEV 993


>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
          Length = 2175

 Score =  191 bits (486), Expect = 6e-48
 Identities = 233/989 (23%), Positives = 409/989 (41%), Gaps = 149/989 (15%)

Query: 541  AGRVRLWIDADKT--ITEVDEEHVHRANPPELDQVEDLASLISVNESSVLNTLLQRYKAQ 598
            +G+V++  D D    I+  +  H+   +P  +  VED+  L  +NE+ +L  LL RY+  
Sbjct: 33   SGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDH 92

Query: 599  LLHTCTGPDLIVLQP-RGPSVPSAGKVPK--GRRDG-LPAHIGSMAQRAYWALLNQRRDQ 654
            L++T TG  L+ + P +  S+ S   + +   ++ G +P HI ++A   Y+ +    RDQ
Sbjct: 93   LIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQ 152

Query: 655  SIVALGWSGAGKTTCCEQVLEHLVGMAGSVDGRVSVEKIRATFTVLRAFGSVSMAHSRSA 714
              +  G SGAGKT   + +L+ L  ++G     +  + + AT  +L AFG+     + ++
Sbjct: 153  CCIISGESGAGKTESTKLILQFLAAISGQ-HSWIEQQVLEAT-PILEAFGNAKTIRNDNS 210

Query: 715  TRFSMVMSLDFNATGRITAAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTEL 774
            +RF   + + FN  G I  A+++  LLEKSRV RQ   E N+ VF  ML G+  D + +L
Sbjct: 211  SRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKL 270

Query: 775  NLHQMADSSSFGMGVWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLG 834
             L Q +D +   MG     E +  +   +A ++ AM++L  +++E   + ++LAAI HLG
Sbjct: 271  GLGQASDYNYLAMGNCITCEGRVDSQE-YANIRSAMKVLMFTDTENWEISKLLAAILHLG 329

Query: 835  AAGACKVGRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGP-------- 886
                              N   EA   E  +     F   L      +   P        
Sbjct: 330  ------------------NLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDLMSCLT 371

Query: 887  SRWGLEDEETSSG--LKMTGVDCVEGMASGLYQELFAAVVSLINRSF-----SSHHLSMA 939
            SR  +   ET S    +   +D  +    G+Y  LF  +V  IN +           S  
Sbjct: 372  SRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRR 431

Query: 940  SIMVVDSPGFQNPRHQGKDRAATFEELCHNYAHERLQLLFYQRTFVSTLQRYQEEGVP-V 998
            SI ++D  GF+N          +FE+LC N+A+E LQ  F +  F    + Y  E +  +
Sbjct: 432  SIGLLDIFGFEN------FAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWL 485

Query: 999  QFDLPDPSPGTTVAVVDQNPSQVRLPAGGGAQDARGLFWVLDEEVHVEGSSDSVVLERLC 1058
              +  D      +                 A     +  ++DEE      +D+ +L +L 
Sbjct: 486  HIEFTDNQDALDMI----------------ANKPMNIISLIDEESKFPKGTDTTMLHKLN 529

Query: 1059 AAFEKKGAGTEGSSALRTCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVL 1118
            +  +         +   T     Q  I H  G   V Y+  G+L + +  L   D  Q++
Sbjct: 530  SQHKLNANYIPPKNNHET-----QFGINHFAGI--VYYETQGFLEKNRDTLHG-DIIQLV 581

Query: 1119 HQSKREELRSLFQARAKLPPVCRAVAGLEGTSQQALQRSRMVRRTFASSLAAVRRKAP-- 1176
            H S+ + ++ +FQA   +                                A  R+++P  
Sbjct: 582  HSSRNKFIKQIFQADVAMG-------------------------------AETRKRSPTL 610

Query: 1177 CSQIKLQMDALTSMIKRSRLHFIHCLVPNPVVESRSGQESPPPPQPGRDKPGAGGPLALD 1236
             SQ K  ++ L   +   +  F+ C+ PN   +                      P+  D
Sbjct: 611  SSQFKRSLELLMRTLGACQPFFVRCIKPNEFKK----------------------PMLFD 648

Query: 1237 IPALRVQLAGFHILEALRLHRTGYADHMGLTRFRRQFQVLDAPLLKKLMSTSEGIDERKA 1296
                  QL    ++E +R+ R GY        F  +++V    LL  +    +  D R  
Sbjct: 649  RHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRV----LLPGVKPAYKQGDLRGT 704

Query: 1297 VEELLETLDLEKKAVAVGHSQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEF 1356
             + + E +        +G +++FLK      LE +R+K ++  ++L Q   +GF  R  F
Sbjct: 705  CQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNF 764

Query: 1357 KKLKIRRLAAQCIQKNVAVFLAVKDWPWWQL-LGSLQPLLSATIGTEQLRAKEEELTTLR 1415
             KLK    AA  IQ++       K++   +L    LQ L  +    +Q R   + +   +
Sbjct: 765  LKLK---NAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQ 821

Query: 1416 RKLEKSEKLRNELRQNTDLLESKIADLTSDLADERF-KGDVACQVLESERAERLQAFREV 1474
             +  ++  +R   R            L + L  + + +G +A ++ +  RAE L    E 
Sbjct: 822  ARC-RAYLVRKAFRHR----------LWAVLTVQAYARGMIARRLHQRLRAEYLWRL-EA 869

Query: 1475 QELKSKHEQVQKKLGDVNKQLEEAQQKIQ 1503
            ++++   E+  +K     K  EEA++K Q
Sbjct: 870  EKMRLAEEEKLRKEMSAKKAKEEAERKHQ 898



 Score = 39.7 bits (91), Expect = 0.039
 Identities = 61/249 (24%), Positives = 96/249 (38%), Gaps = 44/249 (17%)

Query: 1319 FLKAGVISRLEK--QREKLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKNVAVF 1376
            FL+   + R  K  Q+ +L  Q I+ FQA C+ +L R+ F+      L  Q   +     
Sbjct: 794  FLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQAYAR----- 848

Query: 1377 LAVKDWPWWQLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEKLRNEL--RQNTDL 1434
                        G +   L   +  E L   E E    + +L + EKLR E+  ++  + 
Sbjct: 849  ------------GMIARRLHQRLRAEYLWRLEAE----KMRLAEEEKLRKEMSAKKAKEE 892

Query: 1435 LESKIADLTSDLADERFKGDVACQVLESERAERLQAFREVQELKSKHEQVQKKLGDVNKQ 1494
             E K  +  + LA E    D   ++ E E A R +   E  E +++HE V      V+K 
Sbjct: 893  AERKHQERLAQLARE----DAERELKEKEAARRKKELLEQME-RARHEPVNHS-DMVDKM 946

Query: 1495 LEEAQQKIQLNDLERNPTGGADEWQMRFDCAQMENEFLRKRLQQCEERLDSELTARKELE 1554
                     L   E     G ++ +             R R +  EE LD+ L    E E
Sbjct: 947  FGFLGTSGGLPGQEGQAPSGFEDLE-------------RGRREMVEEDLDAALPLPDEDE 993

Query: 1555 QKLGELQSA 1563
            + L E + A
Sbjct: 994  EDLSEYKFA 1002


>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
          Length = 1204

 Score =  191 bits (486), Expect = 6e-48
 Identities = 233/989 (23%), Positives = 409/989 (41%), Gaps = 149/989 (15%)

Query: 541  AGRVRLWIDADKT--ITEVDEEHVHRANPPELDQVEDLASLISVNESSVLNTLLQRYKAQ 598
            +G+V++  D D    I+  +  H+   +P  +  VED+  L  +NE+ +L  LL RY+  
Sbjct: 33   SGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDLNEAGILRNLLIRYRDH 92

Query: 599  LLHTCTGPDLIVLQP-RGPSVPSAGKVPK--GRRDG-LPAHIGSMAQRAYWALLNQRRDQ 654
            L++T TG  L+ + P +  S+ S   + +   ++ G +P HI ++A   Y+ +    RDQ
Sbjct: 93   LIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFAIADNCYFNMKRNSRDQ 152

Query: 655  SIVALGWSGAGKTTCCEQVLEHLVGMAGSVDGRVSVEKIRATFTVLRAFGSVSMAHSRSA 714
              +  G SGAGKT   + +L+ L  ++G     +  + + AT  +L AFG+     + ++
Sbjct: 153  CCIISGESGAGKTESTKLILQFLAAISGQ-HSWIEQQVLEAT-PILEAFGNAKTIRNDNS 210

Query: 715  TRFSMVMSLDFNATGRITAAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTEL 774
            +RF   + + FN  G I  A+++  LLEKSRV RQ   E N+ VF  ML G+  D + +L
Sbjct: 211  SRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKL 270

Query: 775  NLHQMADSSSFGMGVWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLG 834
             L Q +D +   MG     E +  +   +A ++ AM++L  +++E   + ++LAAI HLG
Sbjct: 271  GLGQASDYNYLAMGNCITCEGRVDSQE-YANIRSAMKVLMFTDTENWEISKLLAAILHLG 329

Query: 835  AAGACKVGRKQFMRFEWANYAAEALGCEYEELNTATFKHHLRQIIQQMTFGP-------- 886
                              N   EA   E  +     F   L      +   P        
Sbjct: 330  ------------------NLQYEARTFENLDACEVLFSPSLATAASLLEVNPPDLMSCLT 371

Query: 887  SRWGLEDEETSSG--LKMTGVDCVEGMASGLYQELFAAVVSLINRSF-----SSHHLSMA 939
            SR  +   ET S    +   +D  +    G+Y  LF  +V  IN +           S  
Sbjct: 372  SRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQDVKNSRR 431

Query: 940  SIMVVDSPGFQNPRHQGKDRAATFEELCHNYAHERLQLLFYQRTFVSTLQRYQEEGVP-V 998
            SI ++D  GF+N          +FE+LC N+A+E LQ  F +  F    + Y  E +  +
Sbjct: 432  SIGLLDIFGFEN------FAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWL 485

Query: 999  QFDLPDPSPGTTVAVVDQNPSQVRLPAGGGAQDARGLFWVLDEEVHVEGSSDSVVLERLC 1058
              +  D      +                 A     +  ++DEE      +D+ +L +L 
Sbjct: 486  HIEFTDNQDALDMI----------------ANKPMNIISLIDEESKFPKGTDTTMLHKLN 529

Query: 1059 AAFEKKGAGTEGSSALRTCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVL 1118
            +  +         +   T     Q  I H  G   V Y+  G+L + +  L   D  Q++
Sbjct: 530  SQHKLNANYIPPKNNHET-----QFGINHFAGI--VYYETQGFLEKNRDTLHG-DIIQLV 581

Query: 1119 HQSKREELRSLFQARAKLPPVCRAVAGLEGTSQQALQRSRMVRRTFASSLAAVRRKAP-- 1176
            H S+ + ++ +FQA   +                                A  R+++P  
Sbjct: 582  HSSRNKFIKQIFQADVAMG-------------------------------AETRKRSPTL 610

Query: 1177 CSQIKLQMDALTSMIKRSRLHFIHCLVPNPVVESRSGQESPPPPQPGRDKPGAGGPLALD 1236
             SQ K  ++ L   +   +  F+ C+ PN   +                      P+  D
Sbjct: 611  SSQFKRSLELLMRTLGACQPFFVRCIKPNEFKK----------------------PMLFD 648

Query: 1237 IPALRVQLAGFHILEALRLHRTGYADHMGLTRFRRQFQVLDAPLLKKLMSTSEGIDERKA 1296
                  QL    ++E +R+ R GY        F  +++V    LL  +    +  D R  
Sbjct: 649  RHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRV----LLPGVKPAYKQGDLRGT 704

Query: 1297 VEELLETLDLEKKAVAVGHSQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEF 1356
             + + E +        +G +++FLK      LE +R+K ++  ++L Q   +GF  R  F
Sbjct: 705  CQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNF 764

Query: 1357 KKLKIRRLAAQCIQKNVAVFLAVKDWPWWQL-LGSLQPLLSATIGTEQLRAKEEELTTLR 1415
             KLK    AA  IQ++       K++   +L    LQ L  +    +Q R   + +   +
Sbjct: 765  LKLK---NAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQ 821

Query: 1416 RKLEKSEKLRNELRQNTDLLESKIADLTSDLADERF-KGDVACQVLESERAERLQAFREV 1474
             +  ++  +R   R            L + L  + + +G +A ++ +  RAE L    E 
Sbjct: 822  ARC-RAYLVRKAFRHR----------LWAVLTVQAYARGMIARRLHQRLRAEYLWRL-EA 869

Query: 1475 QELKSKHEQVQKKLGDVNKQLEEAQQKIQ 1503
            ++++   E+  +K     K  EEA++K Q
Sbjct: 870  EKMRLAEEEKLRKEMSAKKAKEEAERKHQ 898



 Score = 39.7 bits (91), Expect = 0.039
 Identities = 61/249 (24%), Positives = 96/249 (38%), Gaps = 44/249 (17%)

Query: 1319 FLKAGVISRLEK--QREKLVSQSIVLFQAACKGFLSRQEFKKLKIRRLAAQCIQKNVAVF 1376
            FL+   + R  K  Q+ +L  Q I+ FQA C+ +L R+ F+      L  Q   +     
Sbjct: 794  FLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTVQAYAR----- 848

Query: 1377 LAVKDWPWWQLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEKLRNEL--RQNTDL 1434
                        G +   L   +  E L   E E    + +L + EKLR E+  ++  + 
Sbjct: 849  ------------GMIARRLHQRLRAEYLWRLEAE----KMRLAEEEKLRKEMSAKKAKEE 892

Query: 1435 LESKIADLTSDLADERFKGDVACQVLESERAERLQAFREVQELKSKHEQVQKKLGDVNKQ 1494
             E K  +  + LA E    D   ++ E E A R +   E  E +++HE V      V+K 
Sbjct: 893  AERKHQERLAQLARE----DAERELKEKEAARRKKELLEQME-RARHEPVNHS-DMVDKM 946

Query: 1495 LEEAQQKIQLNDLERNPTGGADEWQMRFDCAQMENEFLRKRLQQCEERLDSELTARKELE 1554
                     L   E     G ++ +             R R +  EE LD+ L    E E
Sbjct: 947  FGFLGTSGGLPGQEGQAPSGFEDLE-------------RGRREMVEEDLDAALPLPDEDE 993

Query: 1555 QKLGELQSA 1563
            + L E + A
Sbjct: 994  EDLSEYKFA 1002


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.129    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 101,245,494
Number of Sequences: 37866
Number of extensions: 5176597
Number of successful extensions: 47315
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 366
Number of HSP's successfully gapped in prelim test: 1516
Number of HSP's that attempted gapping in prelim test: 23433
Number of HSP's gapped (non-prelim): 11625
length of query: 2567
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2448
effective length of database: 13,741,464
effective search space: 33639103872
effective search space used: 33639103872
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 71 (32.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.