Guide to the Human Genome
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Search of human proteins with 51242947

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|51242947 RecQ protein-like 5 isoform 2 [Homo sapiens]
         (435 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|51242947 RecQ protein-like 5 isoform 2 [Homo sapiens]              876   0.0  
gi|148612816 RecQ protein-like 5 isoform 1 [Homo sapiens]             822   0.0  
gi|51242943 RecQ protein-like 5 isoform 3 [Homo sapiens]              822   0.0  
gi|4557365 Bloom syndrome protein [Homo sapiens]                      278   7e-75
gi|14591902 RecQ protein-like [Homo sapiens]                          261   7e-70
gi|14591904 RecQ protein-like [Homo sapiens]                          261   7e-70
gi|110735439 Werner syndrome protein [Homo sapiens]                   212   6e-55
gi|169218196 PREDICTED: similar to Werner syndrome ATP-dependent...   212   6e-55
gi|116812616 RecQ protein-like 4 [Homo sapiens]                       183   3e-46
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap...    64   2e-10
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]     61   2e-09
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...    57   3e-08
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap...    56   6e-08
gi|13129006 nucleolar protein GU2 [Homo sapiens]                       56   6e-08
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi...    56   6e-08
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]           56   7e-08
gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapi...    56   7e-08
gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapi...    56   7e-08
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]          55   2e-07
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ...    54   2e-07
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [...    54   2e-07
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]             54   4e-07
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]             54   4e-07
gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo sapi...    53   5e-07
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ...    50   4e-06
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [...    50   4e-06
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ...    50   4e-06
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi...    49   9e-06
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap...    49   1e-05
gi|21071032 DEAD-box protein abstrakt [Homo sapiens]                   47   3e-05

>gi|51242947 RecQ protein-like 5 isoform 2 [Homo sapiens]
          Length = 435

 Score =  876 bits (2264), Expect = 0.0
 Identities = 435/435 (100%), Positives = 435/435 (100%)

Query: 1   MSSHHTTFPFDPERRVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSL 60
           MSSHHTTFPFDPERRVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSL
Sbjct: 1   MSSHHTTFPFDPERRVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSL 60

Query: 61  CYQLPALLAKGITIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLEREK 120
           CYQLPALLAKGITIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLEREK
Sbjct: 61  CYQLPALLAKGITIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLEREK 120

Query: 121 PQTKILYITPEMAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALR 180
           PQTKILYITPEMAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALR
Sbjct: 121 PQTKILYITPEMAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALR 180

Query: 181 SRLGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYG 240
           SRLGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYG
Sbjct: 181 SRLGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYG 240

Query: 241 NLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTL 300
           NLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTL
Sbjct: 241 NLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTL 300

Query: 301 VQNDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCR 360
           VQNDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCR
Sbjct: 301 VQNDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCR 360

Query: 361 LYYSRNDRDQVSFLIRKEVAKLQEKRGNKASDKATIMAFDALVTFCEELGRWGRGHGKSL 420
           LYYSRNDRDQVSFLIRKEVAKLQEKRGNKASDKATIMAFDALVTFCEELGRWGRGHGKSL
Sbjct: 361 LYYSRNDRDQVSFLIRKEVAKLQEKRGNKASDKATIMAFDALVTFCEELGRWGRGHGKSL 420

Query: 421 RAAWCSQVVSRHAEL 435
           RAAWCSQVVSRHAEL
Sbjct: 421 RAAWCSQVVSRHAEL 435


>gi|148612816 RecQ protein-like 5 isoform 1 [Homo sapiens]
          Length = 991

 Score =  822 bits (2124), Expect = 0.0
 Identities = 410/410 (100%), Positives = 410/410 (100%)

Query: 1   MSSHHTTFPFDPERRVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSL 60
           MSSHHTTFPFDPERRVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSL
Sbjct: 1   MSSHHTTFPFDPERRVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSL 60

Query: 61  CYQLPALLAKGITIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLEREK 120
           CYQLPALLAKGITIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLEREK
Sbjct: 61  CYQLPALLAKGITIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLEREK 120

Query: 121 PQTKILYITPEMAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALR 180
           PQTKILYITPEMAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALR
Sbjct: 121 PQTKILYITPEMAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALR 180

Query: 181 SRLGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYG 240
           SRLGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYG
Sbjct: 181 SRLGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYG 240

Query: 241 NLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTL 300
           NLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTL
Sbjct: 241 NLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTL 300

Query: 301 VQNDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCR 360
           VQNDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCR
Sbjct: 301 VQNDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCR 360

Query: 361 LYYSRNDRDQVSFLIRKEVAKLQEKRGNKASDKATIMAFDALVTFCEELG 410
           LYYSRNDRDQVSFLIRKEVAKLQEKRGNKASDKATIMAFDALVTFCEELG
Sbjct: 361 LYYSRNDRDQVSFLIRKEVAKLQEKRGNKASDKATIMAFDALVTFCEELG 410


>gi|51242943 RecQ protein-like 5 isoform 3 [Homo sapiens]
          Length = 410

 Score =  822 bits (2124), Expect = 0.0
 Identities = 410/410 (100%), Positives = 410/410 (100%)

Query: 1   MSSHHTTFPFDPERRVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSL 60
           MSSHHTTFPFDPERRVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSL
Sbjct: 1   MSSHHTTFPFDPERRVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSL 60

Query: 61  CYQLPALLAKGITIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLEREK 120
           CYQLPALLAKGITIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLEREK
Sbjct: 61  CYQLPALLAKGITIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLEREK 120

Query: 121 PQTKILYITPEMAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALR 180
           PQTKILYITPEMAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALR
Sbjct: 121 PQTKILYITPEMAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALR 180

Query: 181 SRLGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYG 240
           SRLGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYG
Sbjct: 181 SRLGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYG 240

Query: 241 NLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTL 300
           NLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTL
Sbjct: 241 NLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTL 300

Query: 301 VQNDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCR 360
           VQNDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCR
Sbjct: 301 VQNDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCR 360

Query: 361 LYYSRNDRDQVSFLIRKEVAKLQEKRGNKASDKATIMAFDALVTFCEELG 410
           LYYSRNDRDQVSFLIRKEVAKLQEKRGNKASDKATIMAFDALVTFCEELG
Sbjct: 361 LYYSRNDRDQVSFLIRKEVAKLQEKRGNKASDKATIMAFDALVTFCEELG 410


>gi|4557365 Bloom syndrome protein [Homo sapiens]
          Length = 1417

 Score =  278 bits (711), Expect = 7e-75
 Identities = 163/402 (40%), Positives = 233/402 (57%), Gaps = 19/402 (4%)

Query: 10   FDPERRVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPALLA 69
            F   + +     K FG  +F+T   E+   A++   +D F+ MPTG GKSLCYQLPA ++
Sbjct: 649  FPHTKEMMKIFHKKFGLHNFRTNQLEAINAALL--GEDCFILMPTGGGKSLCYQLPACVS 706

Query: 70   KGITIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLEREKPQTKILYIT 129
             G+T+V+SPL +LI DQV  L +L +  + L    +  E   +   L ++ P  K+LY+T
Sbjct: 707  PGVTVVISPLRSLIVDQVQKLTSLDIPATYLTGDKTDSEATNIYLQLSKKDPIIKLLYVT 766

Query: 130  PE-MAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRLGHAPC 188
            PE + AS+    TL +L  R LL+  V+DEAHCVSQWGHDFR DY R+  LR +    P 
Sbjct: 767  PEKICASNRLISTLENLYERKLLARFVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVPV 826

Query: 189  VALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYGNLKDFCLK 248
            +ALTATA P+VQ+D+   L + +P  +F     R NL Y V  K+     +      CL+
Sbjct: 827  MALTATANPRVQKDILTQLKILRP-QVFSMSFNRHNLKYYVLPKKPKKVAFD-----CLE 880

Query: 249  ALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWM-E 307
             + +         GI+YC +R  C+ +A  L   G+ A AYHAGL  S R  VQ  W+ +
Sbjct: 881  WIRKHHPYD---SGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQ 937

Query: 308  EKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRND 367
            +   VI ATI+FGMG+DK +VRFV H ++ KS+ GYYQESGRAGRDG+ S C L+Y+ +D
Sbjct: 938  DGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHD 997

Query: 368  RDQVSFLIRKEVAKLQEKRGNKASDKATIMAFDALVTFCEEL 409
              ++  LI      + EK GN  + +       ++V +CE +
Sbjct: 998  VTRLKRLI------MMEKDGNHHTRETHFNNLYSMVHYCENI 1033


>gi|14591902 RecQ protein-like [Homo sapiens]
          Length = 649

 Score =  261 bits (668), Expect = 7e-70
 Identities = 146/365 (40%), Positives = 214/365 (58%), Gaps = 10/365 (2%)

Query: 15  RVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPALLAKGITI 74
           +V+  L+ VF  + F+ PLQ   T+ V    K+VF+ MPTG GKSLCYQLPAL + G T+
Sbjct: 78  KVKDILQNVFKLEKFR-PLQLE-TINVTMAGKEVFLVMPTGGGKSLCYQLPALCSDGFTL 135

Query: 75  VVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLEREKPQTKILYITPE-MA 133
           V+ PLI+L++DQ+  L  L +  + LN+  S +  K + A++  +  + K++Y+TPE +A
Sbjct: 136 VICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIA 195

Query: 134 ASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRLGHAPCVALTA 193
            S  F   L         + + VDE HC SQWGHDFRPDY  LG L+ +  +A  + LTA
Sbjct: 196 KSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIGLTA 255

Query: 194 TATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYGNLKDFCLKALGQE 253
           TAT  V  D    L ++K    F     R NL+Y+V+ K        N +DF    +   
Sbjct: 256 TATNHVLTDAQKILCIEKCFT-FTASFNRPNLYYEVRQKP------SNTEDFIEDIVKLI 308

Query: 254 ADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVI 313
             +     GI+YC +++  EQ+ + L   G++A AYHA L+  ++T V   W   ++ V+
Sbjct: 309 NGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVV 368

Query: 314 VATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRNDRDQVSF 373
           VAT++FGMG+DK +VRFV H +++KSM  YYQESGRAGRD   + C LYY   D  ++S 
Sbjct: 369 VATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGFGDIFRISS 428

Query: 374 LIRKE 378
           ++  E
Sbjct: 429 MVVME 433


>gi|14591904 RecQ protein-like [Homo sapiens]
          Length = 649

 Score =  261 bits (668), Expect = 7e-70
 Identities = 146/365 (40%), Positives = 214/365 (58%), Gaps = 10/365 (2%)

Query: 15  RVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPALLAKGITI 74
           +V+  L+ VF  + F+ PLQ   T+ V    K+VF+ MPTG GKSLCYQLPAL + G T+
Sbjct: 78  KVKDILQNVFKLEKFR-PLQLE-TINVTMAGKEVFLVMPTGGGKSLCYQLPALCSDGFTL 135

Query: 75  VVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLEREKPQTKILYITPE-MA 133
           V+ PLI+L++DQ+  L  L +  + LN+  S +  K + A++  +  + K++Y+TPE +A
Sbjct: 136 VICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIA 195

Query: 134 ASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRLGHAPCVALTA 193
            S  F   L         + + VDE HC SQWGHDFRPDY  LG L+ +  +A  + LTA
Sbjct: 196 KSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIGLTA 255

Query: 194 TATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYGNLKDFCLKALGQE 253
           TAT  V  D    L ++K    F     R NL+Y+V+ K        N +DF    +   
Sbjct: 256 TATNHVLTDAQKILCIEKCFT-FTASFNRPNLYYEVRQKP------SNTEDFIEDIVKLI 308

Query: 254 ADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVI 313
             +     GI+YC +++  EQ+ + L   G++A AYHA L+  ++T V   W   ++ V+
Sbjct: 309 NGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVV 368

Query: 314 VATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRNDRDQVSF 373
           VAT++FGMG+DK +VRFV H +++KSM  YYQESGRAGRD   + C LYY   D  ++S 
Sbjct: 369 VATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGFGDIFRISS 428

Query: 374 LIRKE 378
           ++  E
Sbjct: 429 MVVME 433


>gi|110735439 Werner syndrome protein [Homo sapiens]
          Length = 1432

 Score =  212 bits (539), Expect = 6e-55
 Identities = 127/357 (35%), Positives = 210/357 (58%), Gaps = 17/357 (4%)

Query: 12  PERRVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPALLAKG 71
           P     + LK  FG  SFK P+Q     +V++  +D    M TG GKSLC+Q P +    
Sbjct: 532 PNEEQVTCLKMYFGHSSFK-PVQWKVIHSVLEERRDNVAVMATGYGKSLCFQYPPVYVGK 590

Query: 72  ITIVVSPLIALIQDQVDHLLTLKVRVSSLNSK-LSAQERKELLADLEREKPQTKILYITP 130
           I +V+SPLI+L++DQV     L++++S++ +  L + + + +L D++  K   +I+Y+TP
Sbjct: 591 IGLVISPLISLMEDQV-----LQLKMSNIPACFLGSAQSENVLTDIKLGK--YRIVYVTP 643

Query: 131 EMAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRLGHAPCVA 190
           E  + +     L  L +   ++ + VDEAHC+S+WGHDFR  + +LG+L++ L   P VA
Sbjct: 644 EYCSGN--MGLLQQLEADIGITLIAVDEAHCISEWGHDFRDSFRKLGSLKTALPMVPIVA 701

Query: 191 LTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYGNLKDFCLKAL 250
           LTATA+  ++ED+   L+L+ P  I  T   R NL+ +V+ K    +   +L+ F +K  
Sbjct: 702 LTATASSSIREDIVRCLNLRNP-QITCTGFDRPNLYLEVRRKT--GNILQDLQPFLVKTS 758

Query: 251 GQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKV 310
                +G +   I+YC +R+  +Q+  EL    ++   YHAG+  S R  + + ++ +++
Sbjct: 759 SHWEFEGPT---IIYCPSRKMTQQVTGELRKLNLSCGTYHAGMSFSTRKDIHHRFVRDEI 815

Query: 311 PVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRND 367
             ++ATI+FGMG++KA++R V H+   K M  YYQE GRAGRDG  S C + ++  D
Sbjct: 816 QCVIATIAFGMGINKADIRQVIHYGAPKDMESYYQEIGRAGRDGLQSSCHVLWAPAD 872


>gi|169218196 PREDICTED: similar to Werner syndrome ATP-dependent
           helicase, partial [Homo sapiens]
          Length = 1140

 Score =  212 bits (539), Expect = 6e-55
 Identities = 127/357 (35%), Positives = 210/357 (58%), Gaps = 17/357 (4%)

Query: 12  PERRVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPALLAKG 71
           P     + LK  FG  SFK P+Q     +V++  +D    M TG GKSLC+Q P +    
Sbjct: 240 PNEEQVTCLKMYFGHSSFK-PVQWKVIHSVLEERRDNVAVMATGYGKSLCFQYPPVYVGK 298

Query: 72  ITIVVSPLIALIQDQVDHLLTLKVRVSSLNSK-LSAQERKELLADLEREKPQTKILYITP 130
           I +V+SPLI+L++DQV     L++++S++ +  L + + + +L D++  K   +I+Y+TP
Sbjct: 299 IGLVISPLISLMEDQV-----LQLKMSNIPACFLGSAQSENVLTDIKLGK--YRIVYVTP 351

Query: 131 EMAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRLGHAPCVA 190
           E  + +     L  L +   ++ + VDEAHC+S+WGHDFR  + +LG+L++ L   P VA
Sbjct: 352 EYCSGN--MGLLQQLEADIGITLIAVDEAHCISEWGHDFRDSFRKLGSLKTALPMVPIVA 409

Query: 191 LTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYGNLKDFCLKAL 250
           LTATA+  ++ED+   L+L+ P  I  T   R NL+ +V+ K    +   +L+ F +K  
Sbjct: 410 LTATASSSIREDIVRCLNLRNP-QITCTGFDRPNLYLEVRRKT--GNILQDLQPFLVKTS 466

Query: 251 GQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKV 310
                +G +   I+YC +R+  +Q+  EL    ++   YHAG+  S R  + + ++ +++
Sbjct: 467 SHWEFEGPT---IIYCPSRKMTQQVTGELRKLNLSCGTYHAGMSFSTRKDIHHRFVRDEI 523

Query: 311 PVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRND 367
             ++ATI+FGMG++KA++R V H+   K M  YYQE GRAGRDG  S C + ++  D
Sbjct: 524 QCVIATIAFGMGINKADIRQVIHYGAPKDMESYYQEIGRAGRDGLQSSCHVLWAPAD 580


>gi|116812616 RecQ protein-like 4 [Homo sapiens]
          Length = 1208

 Score =  183 bits (464), Expect = 3e-46
 Identities = 137/421 (32%), Positives = 208/421 (49%), Gaps = 53/421 (12%)

Query: 8   FPFDPERRVRSTLKKVF------GFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLC 61
           +   P  ++  T  +VF      G  +F+ P QE A M ++ G   + V +PTGAGKSLC
Sbjct: 454 YSLGPSGQLAETPAEVFQALEQLGHQAFR-PGQERAVMRILSGISTLLV-LPTGAGKSLC 511

Query: 62  YQLPALL----AKGITIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLE 117
           YQLPALL    +  +T+VVSPL++L+ DQV  L    ++ + ++S ++ ++R+ +L  + 
Sbjct: 512 YQLPALLYSRRSPCLTLVVSPLLSLMDDQVSGLPPC-LKAACIHSGMTRKQRESVLQKIR 570

Query: 118 REKPQTKILYITPEMAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRL- 176
               Q  +L +TPE    +   P    L     +++  +DEAHC+SQW H+FRP YLR+ 
Sbjct: 571 AA--QVHVLMLTPEALVGAGGLPPAAQLPP---VAFACIDEAHCLSQWSHNFRPCYLRVC 625

Query: 177 GALRSRLGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELIS 236
             LR R+G    + LTATAT +   DV   L + +   +        NL   V       
Sbjct: 626 KVLRERMGVHCFLGLTATATRRTASDVAQHLAVAEEPDLHGPAPVPTNLHLSVSMDR--- 682

Query: 237 DPYGNLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELS--------------CR 282
               +     L  L  +  + L    I+YC  RE  E++A  L                 
Sbjct: 683 ----DTDQALLTLLQGKRFQNLDSI-IIYCNRREDTERIAALLRTCLHAAWVPGSGGRAP 737

Query: 283 GVNAKAYHAGLKASERTLVQNDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAG 342
              A+AYHAG+ + ER  VQ  +M+ ++ V+VAT++FGMG+D+ +VR V H  +  S   
Sbjct: 738 KTTAEAYHAGMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFES 797

Query: 343 YYQESGRAGRDGKPSWCRLYYSRNDRDQVSFLIRKEVAKLQEKRGNKASDKATIMAFDAL 402
           Y Q  GRAGRDG+P+ C L+      D            L+E R +  +D    +A   L
Sbjct: 798 YVQAVGRAGRDGQPAHCHLFLQPQGED------------LRELRRHVHADSTDFLAVKRL 845

Query: 403 V 403
           V
Sbjct: 846 V 846


>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
           sapiens]
          Length = 796

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 91/420 (21%), Positives = 174/420 (41%), Gaps = 40/420 (9%)

Query: 2   SSHHTTFPFDPERRVRSTLKKV--FGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKS 59
           S +     F      R  LK +   GF    TP+Q++     + G KD+  C  TG GK+
Sbjct: 212 SQYDENLSFQDMNLSRPLLKAITAMGFKQ-PTPIQKACIPVGLLG-KDICACAATGTGKT 269

Query: 60  LCYQLPAL---LAKGITIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLS--AQERKELLA 114
             + LP L   + K     V+ ++ L+  +      L ++V S+  +L+        L  
Sbjct: 270 AAFALPVLERLIYKPRQAPVTRVLVLVPTR-----ELGIQVHSVTRQLAQFCNITTCLAV 324

Query: 115 DLEREKPQTKILYITPEM--AASSSFQPTLNSLVSRHLLSY--LVVDEA-HCVSQWGHDF 169
                K Q   L   P++  A        L++  S HL S   L++DEA   + ++  + 
Sbjct: 325 GGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQ 384

Query: 170 RPDYLRLGALRSRLGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDV 229
             + +R+ +      H   +  +AT T +V++   A++ LK PV IF         F   
Sbjct: 385 MKEIIRMCS-----HHRQTMLFSATMTDEVKD--LASVSLKNPVRIFVNSNTDVAPFLRQ 437

Query: 230 QFKELISDPYGNLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAY 289
           +F  +  +  G+ +      L +     +    +++ +T++   ++ I L   G+     
Sbjct: 438 EFIRIRPNREGDREAIVAALLTRTFTDHV----MLFTQTKKQAHRMHILLGLMGLQVGEL 493

Query: 290 HAGLKASERTLVQNDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGR 349
           H  L  ++R      + +E++ ++VAT     G+D   V+ V ++ +  ++  Y    GR
Sbjct: 494 HGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGR 553

Query: 350 AGRDGKPSWCRLYYSRNDRDQVSFLIRKEVAKLQEKRGNKASDKATIMAFDALVTFCEEL 409
             R G+          ++R  +     KE+ K       KA  KA I+  D ++ F +++
Sbjct: 554 TARAGRAGRSVSLVGEDERKML-----KEIVK-----AAKAPVKARILPQDVILKFRDKI 603


>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
          Length = 614

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 88/344 (25%), Positives = 135/344 (39%), Gaps = 48/344 (13%)

Query: 54  TGAGKSLCYQLPAL--------LAKG---ITIVVSPLIALIQDQVDHLLTLKVRVSSLNS 102
           TG+GK+L Y LPA+        L +G   I +V++P   L Q QV  +     R   L S
Sbjct: 140 TGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQ-QVQQVAAEYCRACRLKS 198

Query: 103 KL--SAQERKELLADLEREKPQTKILYITPEMAASSSFQPTLNSLVSRHLLSYLVVDEAH 160
                   +   + DLER     +I   TP       F     + + R   +YLV+DEA 
Sbjct: 199 TCIYGGAPKGPQIRDLERG---VEICIATPGRLID--FLECGKTNLRR--TTYLVLDEAD 251

Query: 161 CVSQWGHDFRPDYLRL-GALRSRLGHAPCVALTATATPQVQEDVF--------AALHLKK 211
            +   G  F P   ++   +R         A       Q+ ED           AL L  
Sbjct: 252 RMLDMG--FEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSA 309

Query: 212 PVAIFKTPCFRANLFYDVQFKELISDPYGNLKDFCLKALGQEADKGLSGCGIVYCRTREA 271
              I +      ++ +DV+            KD  L  L +E         IV+  T+  
Sbjct: 310 NHNILQI----VDVCHDVE------------KDEKLIRLMEEIMSEKENKTIVFVETKRR 353

Query: 272 CEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVIVATISFGMGVDKANVRFV 331
           C++L  ++   G  A   H      ER  V N++   K P+++AT     G+D  +V+FV
Sbjct: 354 CDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFV 413

Query: 332 AHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRNDRDQVSFLI 375
            +++   S   Y    GR  R  K      +++ N+  QVS LI
Sbjct: 414 INYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLI 457


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 84/381 (22%), Positives = 168/381 (44%), Gaps = 45/381 (11%)

Query: 15  RVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPAL------- 67
           ++ ++LKK  G++   TP+Q  A  A++ G +D+     TG+GK++ + LP         
Sbjct: 382 KILNSLKK-HGYEK-PTPIQTQAIPAIMSG-RDLIGIAKTGSGKTIAFLLPMFRHIMDQR 438

Query: 68  -LAKG---ITIVVSPL----IALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLERE 119
            L +G   I ++++P     + + ++      TL +RV  +       E+   +A+L+R 
Sbjct: 439 SLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQ---IAELKRG 495

Query: 120 KPQTKILYITP----EMAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLR 175
               +I+  TP    +M A++S + T     +   ++Y+V+DEA  +   G  F P  +R
Sbjct: 496 ---AEIIVCTPGRMIDMLAANSGRVT-----NLRRVTYVVLDEADRMFDMG--FEPQVMR 545

Query: 176 LGALRSRLGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELI 235
           +  + +       V  +AT  P+  E   A   L KP+ +      R+ +  DV+ + ++
Sbjct: 546 I--VDNVRPDRQTVMFSATF-PRAME-ALARRILSKPIEVQVGG--RSVVCSDVEQQVIV 599

Query: 236 SDPYGNLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKA 295
            +         L+ LG   +   SG  I++   +E  + L  +L        + H G+  
Sbjct: 600 IEEEKKFLKL-LELLGHYQE---SGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQ 655

Query: 296 SERTLVQNDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGK 355
            +R  + ND+      ++VAT     G+D  ++  V +++       Y   +GR GR G 
Sbjct: 656 YDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGN 715

Query: 356 PSWCRLYYSRNDRDQVSFLIR 376
             +   + + +       +I+
Sbjct: 716 KGYAYTFITEDQARYAGDIIK 736


>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
           sapiens]
          Length = 648

 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 84/403 (20%), Positives = 165/403 (40%), Gaps = 54/403 (13%)

Query: 16  VRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPALLAKGITIV 75
           V   +KK  GF    TP+Q  A   V++G  D+     TG GK+LCY +P      I +V
Sbjct: 253 VMENIKKA-GFQK-PTPIQSQAWPIVLQGI-DLIGVAQTGTGKTLCYLMPGF----IHLV 305

Query: 76  VSPLIALIQDQVDHLLTLKVRVSSLN-----SKLSAQERKELLA--------DLEREKPQ 122
           + P +   +++   L+    R  +L       K S +  + +           +E  K  
Sbjct: 306 LQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYSYKGLRSVCVYGGGNRDEQIEELKKG 365

Query: 123 TKILYITPEMAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSR 182
             I+  TP           +++ V+   ++YLV+DEA  +   G  F P  +++  L   
Sbjct: 366 VDIIIATPGRLNDLQ----MSNFVNLKNITYLVLDEADKMLDMG--FEPQIMKI--LLDV 417

Query: 183 LGHAPCVALTATATPQVQEDVFAALHLKKPVAIF-------KTPCFRANLFYDVQFKELI 235
                 V  +AT    V     A  +LK+P+ ++            + N+    +     
Sbjct: 418 RPDRQTVMTSATWPHSVHR--LAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTE----- 470

Query: 236 SDPYGNLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKA 295
            + + +++ F L+++    DK      IV+   +   + L+ +L    ++ ++ H   + 
Sbjct: 471 EEKWSHMQTF-LQSMSS-TDKV-----IVFVSRKAVADHLSSDLILGNISVESLHGDREQ 523

Query: 296 SERTLVQNDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGK 355
            +R     ++   KV +++AT     G+D  +V  V +++  +++  Y    GR GR G+
Sbjct: 524 RDREKALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGR 583

Query: 356 PSWCRLYYSRNDRDQVSFLIRKEVAKLQEKRGNKASDKATIMA 398
                   +RND     + +  E+  + E+      ++   MA
Sbjct: 584 TGVSITTLTRND-----WRVASELINILERANQSIPEELVSMA 621


>gi|13129006 nucleolar protein GU2 [Homo sapiens]
          Length = 737

 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 32/121 (26%), Positives = 57/121 (47%), Gaps = 1/121 (0%)

Query: 257 GLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVIVAT 316
           G  G  I++C T++   ++A+    +  NA+  H  +  S+R +    + E    V+VAT
Sbjct: 387 GSEGRAIIFCETKKNVTEMAMNPHIKQ-NAQCLHGDIAQSQREITLKGFREGSFKVLVAT 445

Query: 317 ISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRNDRDQVSFLIR 376
                G+D   V  V   +  + +  Y   SGR GR G+   C  +Y   +R Q+ ++ +
Sbjct: 446 NVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTGICICFYQPRERGQLRYVEQ 505

Query: 377 K 377
           K
Sbjct: 506 K 506


>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
           sapiens]
          Length = 820

 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 85/383 (22%), Positives = 152/383 (39%), Gaps = 71/383 (18%)

Query: 31  TPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPALLAKGITIVVSPLIALIQ--DQVD 88
           TP+Q  A + +   N+D+     TG+GK+  + +P L    + I   P I  I+  DQ  
Sbjct: 415 TPIQRQA-IPIGLQNRDIIGVAETGSGKTAAFLIPLL----VWITTLPKIDRIEESDQGP 469

Query: 89  HLLTLKVRVSSLNSKLSAQERK----------ELLADLEREKPQTKILYITPEMAASSSF 138
           + + L      L  ++  +  K           ++  + RE    ++      + A+   
Sbjct: 470 YAIIL-APTRELAQQIEEETIKFGKPLGIRTVAVIGGISREDQGFRLRMGCEIVIATPG- 527

Query: 139 QPTLNSLVSRHLL----SYLVVDEAHCVSQWGHDFRPDYLRLGALRSRLGHAPC------ 188
              ++ L +R+L+    +Y+V+DEA  +   G  F PD  ++      L H P       
Sbjct: 528 -RLIDVLENRYLVLSRCTYVVLDEADRMIDMG--FEPDVQKI------LEHMPVSNQKPD 578

Query: 189 ------------------------VALTATATPQVQEDVFAALHLKKPVAIFKTPCFRAN 224
                                   V  TAT  P V+    A  +L++P  ++     + +
Sbjct: 579 TDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVER--LARSYLRRPAVVYIGSAGKPH 636

Query: 225 LFYDVQFKELISDPYGNLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGV 284
              + Q   L+S+     K   L  L Q  D  +    I++   ++ C+ LA  L   G 
Sbjct: 637 ERVE-QKVFLMSESEKRKK--LLAILEQGFDPPI----IIFVNQKKGCDVLAKSLEKMGY 689

Query: 285 NAKAYHAGLKASERTLVQNDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYY 344
           NA   H G    +R    ++       ++VAT   G G+D  +V  V ++++AK++  Y 
Sbjct: 690 NACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYI 749

Query: 345 QESGRAGRDGKPSWCRLYYSRND 367
              GR GR GK      + ++ D
Sbjct: 750 HRIGRTGRAGKSGVAITFLTKED 772


>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
          Length = 729

 Score = 55.8 bits (133), Expect = 7e-08
 Identities = 93/403 (23%), Positives = 155/403 (38%), Gaps = 46/403 (11%)

Query: 31  TPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPAL--------LAKG---ITIVVSPL 79
           TP+Q       + G +D+     TG+GK+L Y LPA+        L +G   I +V++P 
Sbjct: 195 TPIQCQGFPLALSG-RDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPT 253

Query: 80  IALIQDQVDHLLTLKVRVSSLNSKL--SAQERKELLADLEREKPQTKILYITPEMAASSS 137
             L Q QV  +     + S L S        +   + DLER     +I   TP       
Sbjct: 254 RELAQ-QVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERG---VEICIATPGRLID-- 307

Query: 138 FQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRL-GALRSRLGHAPCVALTATAT 196
           F  +  + + R   +YLV+DEA  +   G  F P   ++   +R         A      
Sbjct: 308 FLESGKTNLRR--CTYLVLDEADRMLDMG--FEPQIRKIVDQIRPDRQTLMWSATWPKEV 363

Query: 197 PQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYGNLKDFCLKALGQEADK 256
            Q+ ED F   + +  V           L  +    +++     + KD  L  L +E   
Sbjct: 364 RQLAED-FLRDYTQINVG-------NLELSANHNILQIVDVCMESEKDHKLIQLMEEIMA 415

Query: 257 GLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVIVAT 316
                 I++  T+  C+ L   +   G  A   H      ER  V N++   K P+++AT
Sbjct: 416 EKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIAT 475

Query: 317 ISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRNDRDQVSFLIR 376
                G+D  +V+FV +++   S   Y    GR  R         +++  +  Q      
Sbjct: 476 DVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQA----- 530

Query: 377 KEVAKLQEKRGNKASDKATIMAFDALVTFCEELGRWGRGHGKS 419
           +E+ K+ E+     + K        L+   +  G  G G G+S
Sbjct: 531 RELIKVLEEANQAINPK--------LMQLVDHRGGGGGGGGRS 565


>gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo
           sapiens]
          Length = 491

 Score = 55.8 bits (133), Expect = 7e-08
 Identities = 81/370 (21%), Positives = 148/370 (40%), Gaps = 27/370 (7%)

Query: 11  DPERRVRSTLKKVFGFDSFK--TPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPALL 68
           D E ++ S L +      F+  TP+Q  A   ++ G +++    PTG+GK+L + +P L+
Sbjct: 59  DQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHG-RELLASAPTGSGKTLAFSIPILM 117

Query: 69  A------KGI-TIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLEREKP 121
                  KG   +++SP   L       L+ +         ++    +  + A     K 
Sbjct: 118 QLKQPANKGFRALIISPTRELASQIHRELIKIS---EGTGFRIHMIHKAAVAAKKFGPKS 174

Query: 122 QTK--ILYITPEMAASSSFQ-PTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGA 178
             K  IL  TP        Q P    L S   + +LVVDE+  + + G     D L    
Sbjct: 175 SKKFDILVTTPNRLIYLLKQDPPGIDLAS---VEWLVVDESDKLFEDGKTGFRDQLASIF 231

Query: 179 LRSRLGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDP 238
           L            +AT    V++  +  L+L   +++        N   +   +EL+   
Sbjct: 232 LACTSHKVRRAMFSATFAYDVEQ--WCKLNLDNVISV---SIGARNSAVETVEQELL--- 283

Query: 239 YGNLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASER 298
           +   +   L A+ +   KG +   +V+ ++ E  ++L  EL   G+N    HA     +R
Sbjct: 284 FVGSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQR 343

Query: 299 TLVQNDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSW 358
               + +   K+ V++ T     G+D   V  V +++   S   Y    GR GR G    
Sbjct: 344 DNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGK 403

Query: 359 CRLYYSRNDR 368
              +++ +D+
Sbjct: 404 AITFFTEDDK 413


>gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo
           sapiens]
          Length = 599

 Score = 55.8 bits (133), Expect = 7e-08
 Identities = 81/370 (21%), Positives = 148/370 (40%), Gaps = 27/370 (7%)

Query: 11  DPERRVRSTLKKVFGFDSFK--TPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPALL 68
           D E ++ S L +      F+  TP+Q  A   ++ G +++    PTG+GK+L + +P L+
Sbjct: 167 DQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHG-RELLASAPTGSGKTLAFSIPILM 225

Query: 69  A------KGI-TIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLEREKP 121
                  KG   +++SP   L       L+ +         ++    +  + A     K 
Sbjct: 226 QLKQPANKGFRALIISPTRELASQIHRELIKIS---EGTGFRIHMIHKAAVAAKKFGPKS 282

Query: 122 QTK--ILYITPEMAASSSFQ-PTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGA 178
             K  IL  TP        Q P    L S   + +LVVDE+  + + G     D L    
Sbjct: 283 SKKFDILVTTPNRLIYLLKQDPPGIDLAS---VEWLVVDESDKLFEDGKTGFRDQLASIF 339

Query: 179 LRSRLGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDP 238
           L            +AT    V++  +  L+L   +++        N   +   +EL+   
Sbjct: 340 LACTSHKVRRAMFSATFAYDVEQ--WCKLNLDNVISV---SIGARNSAVETVEQELL--- 391

Query: 239 YGNLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASER 298
           +   +   L A+ +   KG +   +V+ ++ E  ++L  EL   G+N    HA     +R
Sbjct: 392 FVGSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQR 451

Query: 299 TLVQNDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSW 358
               + +   K+ V++ T     G+D   V  V +++   S   Y    GR GR G    
Sbjct: 452 DNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGK 511

Query: 359 CRLYYSRNDR 368
              +++ +D+
Sbjct: 512 AITFFTEDDK 521


>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
          Length = 731

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 85/360 (23%), Positives = 140/360 (38%), Gaps = 33/360 (9%)

Query: 31  TPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPAL--------LAKG---ITIVVSPL 79
           TP+Q       + G +D+     TG+GK+L Y LPA+        L +G   I +V++P 
Sbjct: 195 TPIQCQGFPLALSG-RDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGPICLVLAPT 253

Query: 80  IALIQDQVDHLLTLKVRVSSLNSKL--SAQERKELLADLEREKPQTKILYITPEMAASSS 137
             L Q QV  +     + S L S        +   + DLER     +I   TP       
Sbjct: 254 RELAQ-QVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERG---VEICIATPGRLID-- 307

Query: 138 FQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRL-GALRSRLGHAPCVALTATAT 196
           F  +  + + R   +YLV+DEA  +   G  F P   ++   +R         A      
Sbjct: 308 FLESGKTNLRR--CTYLVLDEADRMLDMG--FEPQIRKIVDQIRPDRQTLMWSATWPKEV 363

Query: 197 PQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYGNLKDFCLKALGQEADK 256
            Q+ ED F   + +  V           L  +    +++     + KD  L  L +E   
Sbjct: 364 RQLAED-FLRDYTQINVG-------NLELSANHNILQIVDVCMESEKDHKLIQLMEEIMA 415

Query: 257 GLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVIVAT 316
                 I++  T+  C+ L   +   G  A   H      ER  V N++   K P+++AT
Sbjct: 416 EKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIAT 475

Query: 317 ISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRNDRDQVSFLIR 376
                G+D  +V+FV +++   S   Y    GR  R         +++  +  Q   LI+
Sbjct: 476 DVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELIK 535


>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 81/382 (21%), Positives = 148/382 (38%), Gaps = 47/382 (12%)

Query: 31  TPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPALLAKGITIVVSPLIALIQDQ---- 86
           TP+Q+ A + ++KG +D+  C  TG+GK+  + LP +L++  T      +  +++     
Sbjct: 202 TPVQKHA-IPIIKGKRDLMACAQTGSGKTAAFLLP-ILSQIYTDGPGEALKAVKENGRYG 259

Query: 87  ------VDHLLT----LKVRVSSLNSKLSAQERK------------ELLADLEREKPQTK 124
                 +  +L     L V++     K S + R             + + DLER      
Sbjct: 260 RRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERG---CH 316

Query: 125 ILYITPEMAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSR-- 182
           +L  TP        +      +      YLV+DEA  +   G  F P   R+    +   
Sbjct: 317 LLVATPGRLVDMMER----GKIGLDFCKYLVLDEADRMLDMG--FEPQIRRIVEQDTMPP 370

Query: 183 LGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYGNL 242
            G    +  +AT   ++Q      L     +A+ +      N+   V + E +       
Sbjct: 371 KGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDK----- 425

Query: 243 KDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQ 302
           + F L  LG      L+   +V+  T++  + L   L   G    + H      +R    
Sbjct: 426 RSFLLDILGATGSDSLT---LVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEAL 482

Query: 303 NDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLY 362
           + +   K P++VAT     G+D +NVR V ++++   +  Y    GR GR G       +
Sbjct: 483 HQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSF 542

Query: 363 YSRNDRDQVSFLIRKEVAKLQE 384
           ++  + +    L+   V   QE
Sbjct: 543 FNEKNMNITKDLLDLLVEAKQE 564


>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 81/382 (21%), Positives = 148/382 (38%), Gaps = 47/382 (12%)

Query: 31  TPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPALLAKGITIVVSPLIALIQDQ---- 86
           TP+Q+ A + ++KG +D+  C  TG+GK+  + LP +L++  T      +  +++     
Sbjct: 202 TPVQKHA-IPIIKGKRDLMACAQTGSGKTAAFLLP-ILSQIYTDGPGEALKAVKENGRYG 259

Query: 87  ------VDHLLT----LKVRVSSLNSKLSAQERK------------ELLADLEREKPQTK 124
                 +  +L     L V++     K S + R             + + DLER      
Sbjct: 260 RRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERG---CH 316

Query: 125 ILYITPEMAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSR-- 182
           +L  TP        +      +      YLV+DEA  +   G  F P   R+    +   
Sbjct: 317 LLVATPGRLVDMMER----GKIGLDFCKYLVLDEADRMLDMG--FEPQIRRIVEQDTMPP 370

Query: 183 LGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYGNL 242
            G    +  +AT   ++Q      L     +A+ +      N+   V + E +       
Sbjct: 371 KGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDK----- 425

Query: 243 KDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQ 302
           + F L  LG      L+   +V+  T++  + L   L   G    + H      +R    
Sbjct: 426 RSFLLDILGATGSDSLT---LVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEAL 482

Query: 303 NDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLY 362
           + +   K P++VAT     G+D +NVR V ++++   +  Y    GR GR G       +
Sbjct: 483 HQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSF 542

Query: 363 YSRNDRDQVSFLIRKEVAKLQE 384
           ++  + +    L+   V   QE
Sbjct: 543 FNEKNMNITKDLLDLLVEAKQE 564


>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 31/118 (26%), Positives = 58/118 (49%)

Query: 259 SGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVIVATIS 318
           SG  +++   +   E+LA  L   G N    H  +  SER  V +D+ ++ +PV+VAT  
Sbjct: 498 SGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDV 557

Query: 319 FGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRNDRDQVSFLIR 376
              G+D  +++ V ++++A+ +  +    GR GR G+        +  D +    L+R
Sbjct: 558 AARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVR 615


>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 31/118 (26%), Positives = 58/118 (49%)

Query: 259 SGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVIVATIS 318
           SG  +++   +   E+LA  L   G N    H  +  SER  V +D+ ++ +PV+VAT  
Sbjct: 498 SGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDV 557

Query: 319 FGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRNDRDQVSFLIR 376
              G+D  +++ V ++++A+ +  +    GR GR G+        +  D +    L+R
Sbjct: 558 AARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVR 615


>gi|55749865 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Homo
           sapiens]
          Length = 631

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 81/384 (21%), Positives = 153/384 (39%), Gaps = 44/384 (11%)

Query: 31  TPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPALLAKGITIVVSPLIALIQDQVDHL 90
           TP+Q  A   +++G  D+ V   TG GK+L Y +P     G   + S  I+  Q     +
Sbjct: 246 TPIQSQAWPIILQGI-DLIVVAQTGTGKTLSYLMP-----GFIHLDSQPISREQRNGPGM 299

Query: 91  LTLK------VRVSSLNSKLSAQERKELL--------ADLEREKPQTKILYITPEMAASS 136
           L L       + V +  SK S +  K +           +E       I+  TP      
Sbjct: 300 LVLTPTRELALHVEAECSKYSYKGLKSICIYGGRNRNGQIEDISKGVDIIIATPGRLNDL 359

Query: 137 SFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRLGHAPCVALTATAT 196
                +N+ V+   ++YLV+DEA        +F P   ++  L         V  +AT  
Sbjct: 360 Q----MNNSVNLRSITYLVIDEAD--KMLDMEFEPQIRKI--LLDVRPDRQTVMTSATWP 411

Query: 197 PQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYGNLKDFCLKALGQEADK 256
             V++   A  +LK P+ ++       NL      K+ I       K    +AL QE  +
Sbjct: 412 DTVRQ--LALSYLKDPMIVY---VGNLNLVAVNTVKQNIIVTTEKEK----RALTQEFVE 462

Query: 257 GLSGCG--IVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVIV 314
            +S     I++   +   + L+ + + +G++A++ H   + S++     D+    + +++
Sbjct: 463 NMSPNDKVIMFVSQKHIADDLSSDFNIQGISAESLHGNSEQSDQERAVEDFKSGNIKILI 522

Query: 315 ATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRNDRDQVSFL 374
            T     G+D  +V  V +++  +++  Y    G  GR GK        ++ D       
Sbjct: 523 TTDIVSRGLDLNDVTHVYNYDFPRNIDVYVHRVGYIGRTGKTGTSVTLITQRDSKMAG-- 580

Query: 375 IRKEVAKLQEKRGNKASDKATIMA 398
              E+ K+ ++      +   +MA
Sbjct: 581 ---ELIKILDRANQSVPEDLVVMA 601


>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
           [Homo sapiens]
          Length = 724

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 79/344 (22%), Positives = 135/344 (39%), Gaps = 40/344 (11%)

Query: 31  TPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPAL---LAKGIT------------IV 75
           TP+Q+ +   ++ G +D+  C  TG+GK+  + LP L   +  GIT            I+
Sbjct: 312 TPVQKYSIPIILAG-RDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQEPECII 370

Query: 76  VSPLIALIQDQVDHLLTLKVRVSSLNSKLSA---QERKELLADLEREKPQTKILYITPEM 132
           V+P   L+       + L+ R  S  + + A       +L   + +      IL  TP  
Sbjct: 371 VAPTRELVNQ-----IYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGR 425

Query: 133 AASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRLGHAPCVALT 192
                 +      +    + YLV+DEA  +   G  F P+  +L +            L 
Sbjct: 426 LMDIIGKEK----IGLKQIKYLVLDEADRMLDMG--FGPEMKKLISCPGMPSKEQRQTLM 479

Query: 193 ATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYGNLKDFC--LKAL 250
            +AT   +    AA  LK    +F           DVQ   L    +   +     L+ +
Sbjct: 480 FSATFPEEIQRLAAEFLKSNY-LFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNI 538

Query: 251 GQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKV 310
           G E         +V+  T++  + +A  L    ++  + H   +  ER     D+   K 
Sbjct: 539 GDERT-------MVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKC 591

Query: 311 PVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDG 354
           PV+VAT     G+D  NV+ V ++++  ++  Y    GR GR G
Sbjct: 592 PVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCG 635


>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
           [Homo sapiens]
          Length = 724

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 79/344 (22%), Positives = 135/344 (39%), Gaps = 40/344 (11%)

Query: 31  TPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPAL---LAKGIT------------IV 75
           TP+Q+ +   ++ G +D+  C  TG+GK+  + LP L   +  GIT            I+
Sbjct: 312 TPVQKYSIPIILAG-RDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQEPECII 370

Query: 76  VSPLIALIQDQVDHLLTLKVRVSSLNSKLSA---QERKELLADLEREKPQTKILYITPEM 132
           V+P   L+       + L+ R  S  + + A       +L   + +      IL  TP  
Sbjct: 371 VAPTRELVNQ-----IYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGR 425

Query: 133 AASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRLGHAPCVALT 192
                 +      +    + YLV+DEA  +   G  F P+  +L +            L 
Sbjct: 426 LMDIIGKEK----IGLKQIKYLVLDEADRMLDMG--FGPEMKKLISCPGMPSKEQRQTLM 479

Query: 193 ATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYGNLKDFC--LKAL 250
            +AT   +    AA  LK    +F           DVQ   L    +   +     L+ +
Sbjct: 480 FSATFPEEIQRLAAEFLKSNY-LFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNI 538

Query: 251 GQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKV 310
           G E         +V+  T++  + +A  L    ++  + H   +  ER     D+   K 
Sbjct: 539 GDERT-------MVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKC 591

Query: 311 PVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDG 354
           PV+VAT     G+D  NV+ V ++++  ++  Y    GR GR G
Sbjct: 592 PVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCG 635


>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
           [Homo sapiens]
          Length = 690

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 79/344 (22%), Positives = 135/344 (39%), Gaps = 40/344 (11%)

Query: 31  TPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPAL---LAKGIT------------IV 75
           TP+Q+ +   ++ G +D+  C  TG+GK+  + LP L   +  GIT            I+
Sbjct: 278 TPVQKYSIPIILAG-RDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQEPECII 336

Query: 76  VSPLIALIQDQVDHLLTLKVRVSSLNSKLSA---QERKELLADLEREKPQTKILYITPEM 132
           V+P   L+       + L+ R  S  + + A       +L   + +      IL  TP  
Sbjct: 337 VAPTRELVNQ-----IYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGR 391

Query: 133 AASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRLGHAPCVALT 192
                 +      +    + YLV+DEA  +   G  F P+  +L +            L 
Sbjct: 392 LMDIIGKEK----IGLKQIKYLVLDEADRMLDMG--FGPEMKKLISCPGMPSKEQRQTLM 445

Query: 193 ATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYGNLKDFC--LKAL 250
            +AT   +    AA  LK    +F           DVQ   L    +   +     L+ +
Sbjct: 446 FSATFPEEIQRLAAEFLKSNY-LFVAVGQVGGACRDVQQTVLQVGQFSKREKLVEILRNI 504

Query: 251 GQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKV 310
           G E         +V+  T++  + +A  L    ++  + H   +  ER     D+   K 
Sbjct: 505 GDERT-------MVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKC 557

Query: 311 PVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDG 354
           PV+VAT     G+D  NV+ V ++++  ++  Y    GR GR G
Sbjct: 558 PVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCG 601


>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
           sapiens]
          Length = 783

 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 37/152 (24%), Positives = 65/152 (42%), Gaps = 7/152 (4%)

Query: 257 GLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVIVAT 316
           G  G  I++C T++  ++L+ + S    +A++ H  +   +R +    +      V+VAT
Sbjct: 436 GHQGRTIIFCETKKEAQELS-QNSAIKQDAQSLHGDIPQKQREITLKGFRNGSFGVLVAT 494

Query: 317 ISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRNDRDQVSFLIR 376
                G+D   V  V   +  K +  Y   SGR GR G+   C  +Y   +  Q+  + +
Sbjct: 495 NVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFYQHKEEYQLVQVEQ 554

Query: 377 KEVAKLQE------KRGNKASDKATIMAFDAL 402
           K   K +           KAS K  I   D++
Sbjct: 555 KAGIKFKRIGVPSATEIIKASSKDAIRLLDSV 586


>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
           sapiens]
          Length = 619

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 77/353 (21%), Positives = 138/353 (39%), Gaps = 40/353 (11%)

Query: 31  TPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPALLAKGITIVVSPLIALIQDQVDHL 90
           TP+Q       + G +D+     TG+GK+  + LP ++ + +    +P   ++    +  
Sbjct: 227 TPIQMQMIPVGLLG-RDILASADTGSGKTAAFLLPVIM-RALFESKTPSALILTPTRELA 284

Query: 91  LTLKVRVSSLNSKLSAQERKELLADLE------REKPQTKILYITPEMAASSSFQPTLNS 144
           + ++ +   L S L   +   L+  L       R +   K++  TP        Q    S
Sbjct: 285 IQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHVKVIIATPGRLLDIIKQ----S 340

Query: 145 LVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRLGHAP--CVALTATATPQVQED 202
            V    +  +VVDEA  + + G  F+   L +      L + P  C  +  +AT     +
Sbjct: 341 SVELCGVKIVVVDEADTMLKMG--FQQQVLDI------LENIPNDCQTILVSATIPTSIE 392

Query: 203 VFAALHLKKPVAIF----KTPCFRANLFYDVQFKELISDPYGNLKDFCL---KALGQEAD 255
             A+  L  PV I       PC         Q    + DP    K F +   K L +   
Sbjct: 393 QLASQLLHNPVRIITGEKNLPCANVR-----QIILWVEDPAKKKKLFEILNDKKLFKPPV 447

Query: 256 KGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVIVA 315
                C +      EA +++       G+ + + H+     ER  +    +E    V+V+
Sbjct: 448 LVFVDCKLGADLLSEAVQKIT------GLKSISIHSEKSQIERKNILKGLLEGDYEVVVS 501

Query: 316 TISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRNDR 368
           T   G G+D  +VR V ++++  SM  Y  + GR GR G+      + + N +
Sbjct: 502 TGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSK 554


>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
          Length = 622

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 77/356 (21%), Positives = 135/356 (37%), Gaps = 65/356 (18%)

Query: 31  TPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPALL----------------AKGITI 74
           TP+Q      ++ G +D+     TG+GK+L + LP ++                  G+ I
Sbjct: 205 TPIQIQGIPTILSG-RDMIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPFSKREGPYGLII 263

Query: 75  VVSPLIA------------LIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLEREKPQ 122
             S  +A            L+Q+    LL   + +  ++ K            +E  +  
Sbjct: 264 CPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGMSVK----------EQMETIRHG 313

Query: 123 TKILYITPEMAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSR 182
             ++  TP              +VS  +  YL +DEA  +   G +        G +R+ 
Sbjct: 314 VHMMVATP----GRLMDLLQKKMVSLDICRYLALDEADRMIDMGFE--------GDIRTI 361

Query: 183 L----GHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDP 238
                G    +  +AT   ++Q   FA   L KPV I       A+L   +Q  E + + 
Sbjct: 362 FSYFKGQRQTLLFSATMPKKIQN--FAKSALVKPVTINVGRAGAASLDV-IQEVEYVKEE 418

Query: 239 YGNLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASER 298
              +  + L+ L +     L     ++   +   + +   L  +GV A A H G    ER
Sbjct: 419 AKMV--YLLECLQKTPPPVL-----IFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEER 471

Query: 299 TLVQNDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDG 354
           T     + E K  V+VAT     G+D   ++ V ++++ + +  Y    GR GR G
Sbjct: 472 TKAIEAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSG 527


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.134    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,675,353
Number of Sequences: 37866
Number of extensions: 651557
Number of successful extensions: 1682
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 55
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 1555
Number of HSP's gapped (non-prelim): 122
length of query: 435
length of database: 18,247,518
effective HSP length: 105
effective length of query: 330
effective length of database: 14,271,588
effective search space: 4709624040
effective search space used: 4709624040
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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