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Search of human proteins with 50962817
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50962817 TWIST neighbor [Homo sapiens]
(338 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50962817 TWIST neighbor [Homo sapiens] 687 0.0
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 49 8e-06
gi|32483374 nucleolar protein 5A [Homo sapiens] 47 2e-05
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 45 7e-05
gi|168229156 NFKB activating protein [Homo sapiens] 45 9e-05
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 45 1e-04
gi|118421089 chromodomain helicase DNA binding protein 2 isoform... 44 2e-04
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 44 2e-04
gi|32130516 serologically defined colon cancer antigen 1 [Homo s... 43 4e-04
gi|156104891 general transcription factor IIF, polypeptide 1, 74... 43 4e-04
gi|125656165 THO complex 2 [Homo sapiens] 41 0.001
gi|56090620 NFKB activating protein-like [Homo sapiens] 41 0.001
gi|7706254 NOP58 ribonucleoprotein homolog [Homo sapiens] 41 0.002
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 41 0.002
gi|33356550 G patch domain containing 4 isoform 2 [Homo sapiens] 41 0.002
gi|33356552 G patch domain containing 4 isoform 1 [Homo sapiens] 41 0.002
gi|33356179 transcription termination factor, RNA polymerase I [... 40 0.003
gi|221219020 NYD-SP11 protein [Homo sapiens] 40 0.004
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 40 0.004
gi|34482047 adaptor-related protein complex 3, beta 2 subunit [H... 39 0.005
gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo sa... 39 0.005
gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo sa... 39 0.005
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 39 0.005
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 39 0.005
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 39 0.005
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 39 0.005
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 39 0.005
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 39 0.005
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 39 0.005
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 39 0.005
>gi|50962817 TWIST neighbor [Homo sapiens]
Length = 338
Score = 687 bits (1774), Expect = 0.0
Identities = 338/338 (100%), Positives = 338/338 (100%)
Query: 1 MAAGCSEAPRPAAASDGSLVGQAGVLPCLELPTYAAACALVNSRYSCLVAGPHQRHIALS 60
MAAGCSEAPRPAAASDGSLVGQAGVLPCLELPTYAAACALVNSRYSCLVAGPHQRHIALS
Sbjct: 1 MAAGCSEAPRPAAASDGSLVGQAGVLPCLELPTYAAACALVNSRYSCLVAGPHQRHIALS 60
Query: 61 PRYLNRKRTGIREQLDAELLRYSESLLGVPIAYDNIKVVGELGDIYDDQGHIHLNIEADF 120
PRYLNRKRTGIREQLDAELLRYSESLLGVPIAYDNIKVVGELGDIYDDQGHIHLNIEADF
Sbjct: 61 PRYLNRKRTGIREQLDAELLRYSESLLGVPIAYDNIKVVGELGDIYDDQGHIHLNIEADF 120
Query: 121 VIFCPEPGQKLMGIVNKVSSSHIGCLVHGCFNASIPKPEQLSAEQWQTMEINMGDELEFE 180
VIFCPEPGQKLMGIVNKVSSSHIGCLVHGCFNASIPKPEQLSAEQWQTMEINMGDELEFE
Sbjct: 121 VIFCPEPGQKLMGIVNKVSSSHIGCLVHGCFNASIPKPEQLSAEQWQTMEINMGDELEFE 180
Query: 181 VFRLDSDAAGVFCIRGKLNITSLQFKRSEVSEEVTENGTEEAAKKPKKKKKKKDPETYEV 240
VFRLDSDAAGVFCIRGKLNITSLQFKRSEVSEEVTENGTEEAAKKPKKKKKKKDPETYEV
Sbjct: 181 VFRLDSDAAGVFCIRGKLNITSLQFKRSEVSEEVTENGTEEAAKKPKKKKKKKDPETYEV 240
Query: 241 DSGTTKLADDADDTPMEESALQNTNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSS 300
DSGTTKLADDADDTPMEESALQNTNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSS
Sbjct: 241 DSGTTKLADDADDTPMEESALQNTNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSS 300
Query: 301 GYQSDHKKKKKKRKHSEEAEFTPPLKCSPKRKGKSNFL 338
GYQSDHKKKKKKRKHSEEAEFTPPLKCSPKRKGKSNFL
Sbjct: 301 GYQSDHKKKKKKRKHSEEAEFTPPLKCSPKRKGKSNFL 338
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 48.5 bits (114), Expect = 8e-06
Identities = 32/131 (24%), Positives = 62/131 (47%), Gaps = 22/131 (16%)
Query: 206 KRSEVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTN 265
+ +E +EE E +E +K K+K+K+K+ E + T K + ++
Sbjct: 11 EETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEE------------ 58
Query: 266 NANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDH----KKKKKKRKHSEEAEF 321
E++ K+K+KKKK +E ++++ + + + + KKKKK+R+ EE E
Sbjct: 59 ------EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112
Query: 322 TPPLKCSPKRK 332
+ K+K
Sbjct: 113 KKKRRRKTKKK 123
Score = 48.1 bits (113), Expect = 1e-05
Identities = 31/115 (26%), Positives = 56/115 (48%), Gaps = 12/115 (10%)
Query: 206 KRSEVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTN 265
K +E +EE TE EE K+ K+K+K+K+ + TK + + EE
Sbjct: 8 KETEETEE-TEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK----- 61
Query: 266 NANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEEAE 320
+ +KKKK+++ +E ++++ + + + +KKKKKR+ EE E
Sbjct: 62 ------RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEE 110
Score = 35.0 bits (79), Expect = 0.096
Identities = 21/59 (35%), Positives = 35/59 (59%), Gaps = 5/59 (8%)
Query: 276 KKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEEAEFTPPLKCSPKRKGK 334
KKKKKKK+ +E ++ + + + G + + K+K+KRK E+ + T K + KRK K
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKE--KRKEKRKEKEKKKKT---KETEKRKEK 55
Score = 34.7 bits (78), Expect = 0.12
Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 17/93 (18%)
Query: 228 KKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTNNANGIWEEEPKKKKKKKKHQEV 287
KKKKKK ET E + + ++T EE +E +K+K+KKK +
Sbjct: 1 KKKKKKKKETEETE--------ETEETEEEEEKEGKRKEKR----KEKRKEKEKKKKTKE 48
Query: 288 QDQDPVFQGSDSSGYQSDHKKKKKKRKHSEEAE 320
+ + + + K+K+KK+K EE E
Sbjct: 49 TE-----KRKEKEEEEKKRKRKRKKKKEEEERE 76
Score = 28.9 bits (63), Expect = 6.8
Identities = 13/28 (46%), Positives = 19/28 (67%)
Query: 307 KKKKKKRKHSEEAEFTPPLKCSPKRKGK 334
KKKKKK+K +EE E T + +++GK
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGK 28
>gi|32483374 nucleolar protein 5A [Homo sapiens]
Length = 594
Score = 47.4 bits (111), Expect = 2e-05
Identities = 36/120 (30%), Positives = 53/120 (44%), Gaps = 16/120 (13%)
Query: 206 KRSEVSEEVTENGTEEAA---KKPKKKKKKKDPETYEVD----SGTTKLADDADDTPMEE 258
K+ + E ENG E+ + KPKKKK E D +G+T + TP EE
Sbjct: 483 KKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEELMSSDLEETAGSTSIPKRKKSTPKEE 542
Query: 259 SALQNTNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEE 318
+ EE + KK ++ ++PV G + + +S KKKKK K S+E
Sbjct: 543 TVND---------PEEAGHRSGSKKKRKFSKEEPVSSGPEEAVGKSSSKKKKKFHKASQE 593
Score = 36.2 bits (82), Expect = 0.043
Identities = 32/124 (25%), Positives = 49/124 (39%), Gaps = 11/124 (8%)
Query: 209 EVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTNNAN 268
E + E E K K++KK+ E + + ++++ TP E +
Sbjct: 423 EAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALASSENSSSTPEECEEMS------ 476
Query: 269 GIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEEAEFTPPLKCS 328
E KKKKK+K QEV ++ + S S K K+ S + E T
Sbjct: 477 -----EKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEELMSSDLEETAGSTSI 531
Query: 329 PKRK 332
PKRK
Sbjct: 532 PKRK 535
Score = 28.5 bits (62), Expect = 8.9
Identities = 15/43 (34%), Positives = 22/43 (51%)
Query: 201 TSLQFKRSEVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSG 243
TS+ ++ +E T N EEA + KKK+K + V SG
Sbjct: 529 TSIPKRKKSTPKEETVNDPEEAGHRSGSKKKRKFSKEEPVSSG 571
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 45.4 bits (106), Expect = 7e-05
Identities = 32/124 (25%), Positives = 59/124 (47%), Gaps = 31/124 (25%)
Query: 209 EVSEEVTENGTEEAAKK-------------PKKKKKKKDPETYEVDSGTTKLADDADDTP 255
EV E+ T+ A+K PK K KK++ + ++ S ++ + D+D +
Sbjct: 149 EVVREIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSS 208
Query: 256 MEESALQNTNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKH 315
+S+ ++++ + E K KK+KKKH++ HKK+KKKRK
Sbjct: 209 DSQSSSDSSDSESA---TEEKSKKRKKKHRK---------------NSRKHKKEKKKRKK 250
Query: 316 SEEA 319
S+++
Sbjct: 251 SKKS 254
Score = 32.0 bits (71), Expect = 0.81
Identities = 25/121 (20%), Positives = 52/121 (42%), Gaps = 7/121 (5%)
Query: 197 KLNITSLQFKRSEVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPM 256
K N +R+ ++ +N ++ AK + K K+ ++ E DS + ++
Sbjct: 430 KSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNR-----NEEKR 484
Query: 257 EESALQNTNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHS 316
S + ++ N +E+ K+ K K QE + +S + DH K K+K + +
Sbjct: 485 MRSRSKGRDHENV--KEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRA 542
Query: 317 E 317
+
Sbjct: 543 Q 543
Score = 28.5 bits (62), Expect = 8.9
Identities = 19/71 (26%), Positives = 30/71 (42%), Gaps = 12/71 (16%)
Query: 277 KKKKKKKHQEVQDQDPVFQGSDSSGYQ------------SDHKKKKKKRKHSEEAEFTPP 324
KK++KK+H+ SDSS ++ K KK+K+KH + +
Sbjct: 184 KKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKK 243
Query: 325 LKCSPKRKGKS 335
K K+ KS
Sbjct: 244 EKKKRKKSKKS 254
Score = 28.5 bits (62), Expect = 8.9
Identities = 22/85 (25%), Positives = 36/85 (42%), Gaps = 13/85 (15%)
Query: 215 TENGTEEAAKKPKKK-------------KKKKDPETYEVDSGTTKLADDADDTPMEESAL 261
+E+ TEE +KK KKK K+KK ++ +S L T E
Sbjct: 219 SESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIP 278
Query: 262 QNTNNANGIWEEEPKKKKKKKKHQE 286
N + + PK +K++K++E
Sbjct: 279 PIPENRFLMRKSPPKADEKERKNRE 303
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 45.1 bits (105), Expect = 9e-05
Identities = 35/135 (25%), Positives = 56/135 (41%), Gaps = 3/135 (2%)
Query: 202 SLQFKRSEVSEEVTENGTEEA-AKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESA 260
SL+ KR E + E G E PK + D T D K A + EE
Sbjct: 125 SLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSASTS--EEEK 182
Query: 261 LQNTNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEEAE 320
+ ++ + ++ KKK K+KH++ + S++ D+K++ KK K E+ +
Sbjct: 183 KKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKK 242
Query: 321 FTPPLKCSPKRKGKS 335
K KR KS
Sbjct: 243 KHRSKKYKKKRSKKS 257
Score = 43.1 bits (100), Expect = 4e-04
Identities = 29/112 (25%), Positives = 51/112 (45%), Gaps = 6/112 (5%)
Query: 209 EVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTNNAN 268
E ++ + E + K+ KKK K+ + Y DS D D+ + S N A
Sbjct: 180 EEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDS------DSDSDSETDSSDEDNKRRAK 233
Query: 269 GIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEEAE 320
++E KKK + KK+++ + + + SDSS +S + + K +AE
Sbjct: 234 KAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAE 285
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 44.7 bits (104), Expect = 1e-04
Identities = 34/133 (25%), Positives = 66/133 (49%), Gaps = 23/133 (17%)
Query: 206 KRSEVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTN 265
K E S E +G E ++KK ++KKK+K S S+ +++
Sbjct: 71 KELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSS----------------SSSSDSS 114
Query: 266 NANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKK---KKKRKHSEEAEFT 322
+++ E+E KK+ K++K ++ + ++ S SS ++S+ + K KKK+K +E E
Sbjct: 115 SSSSDSEDEEKKQGKRRKKKKNRS----YKSSQSSTHESESESKESVKKKKKSKDETEKE 170
Query: 323 PPLKCSPKRKGKS 335
++ K++ KS
Sbjct: 171 KDVRSLSKKRKKS 183
Score = 42.7 bits (99), Expect = 5e-04
Identities = 29/110 (26%), Positives = 54/110 (49%), Gaps = 3/110 (2%)
Query: 207 RSEVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTNN 266
RS S + + + +E +K+ KKKKK ET E + L+ + ++ L + ++
Sbjct: 137 RSYKSSQSSTHESESESKESVKKKKKSKDET-EKEKDVRSLSKKRKKSYPDDKPLSSESS 195
Query: 267 ANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHS 316
+ +EE+ + KKK++ + Q ++ V + H KKKKK+ S
Sbjct: 196 SESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQ--HKKHSKKKKKKSGS 243
Score = 41.2 bits (95), Expect = 0.001
Identities = 31/142 (21%), Positives = 62/142 (43%), Gaps = 5/142 (3%)
Query: 195 RGKLNITSLQFKRSEVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDT 254
R K + S S S + + +E K+ K++KKKK+ +Y+ +T ++
Sbjct: 97 RKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKN-RSYKSSQSST----HESES 151
Query: 255 PMEESALQNTNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRK 314
+ES + + + +E+ + KK+ + D P+ S S + + KKKR+
Sbjct: 152 ESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKKKRR 211
Query: 315 HSEEAEFTPPLKCSPKRKGKSN 336
E + +K K++ K +
Sbjct: 212 CEEREQAKEKVKKKKKKQHKKH 233
>gi|118421089 chromodomain helicase DNA binding protein 2 isoform 1
[Homo sapiens]
Length = 1828
Score = 44.3 bits (103), Expect = 2e-04
Identities = 34/115 (29%), Positives = 54/115 (46%), Gaps = 9/115 (7%)
Query: 203 LQFKRSEVSEEVTENGTEEAA---KKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEES 259
L+ R + ++ G EEA +KP+ KK+ K P E + G + D P EE
Sbjct: 1318 LKLLRKGLEKKGAVTGGEEAKLKKRKPRVKKENKVPRLKE-EHGIELSSPRHSDNPSEEG 1376
Query: 260 ALQNTNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRK 314
+++ +G+ E+ P KKK+KKK + + + D G + K K KK K
Sbjct: 1377 EVKD----DGL-EKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEK 1426
Score = 31.6 bits (70), Expect = 1.1
Identities = 24/122 (19%), Positives = 53/122 (43%), Gaps = 11/122 (9%)
Query: 207 RSEVSEEVTENGTEEAAKK-------PKKKKKKKDPETYEVDSGTTKLADDADDTPMEES 259
R + EE + +G+E + K K++K K++P E + GT+ ++
Sbjct: 121 RFNIKEEAS-SGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARR 179
Query: 260 ALQNTNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEEA 319
+ +++PK ++ K+K Q+ D+D D + + ++ K + E+
Sbjct: 180 PVPRRTVPKPRVKKQPKTQRGKRKKQDSSDED---DDDDEAPKRQTRRRAAKNVSYKEDD 236
Query: 320 EF 321
+F
Sbjct: 237 DF 238
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 43.9 bits (102), Expect = 2e-04
Identities = 37/133 (27%), Positives = 64/133 (48%), Gaps = 9/133 (6%)
Query: 207 RSEVSEEVTENGTEEAAK-KPKKKKKKKDPETYEVDSGTTK--LADDADDTPMEESALQN 263
++EV+E+ + +AAK K KK+ K PE + + K +A D TP+++
Sbjct: 617 KAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPK 676
Query: 264 TNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEEAEFTP 323
++E KK++KK+ +EV+ + P + + KK++KK EE E
Sbjct: 677 KEEVKKEVKKEIKKEEKKEPKKEVKKETP------PKEVKKEVKKEEKKEVKKEEKEPKK 730
Query: 324 PLKCSPKRKGKSN 336
+K PK KS+
Sbjct: 731 EIKKLPKDAKKSS 743
Score = 35.8 bits (81), Expect = 0.056
Identities = 34/129 (26%), Positives = 53/129 (41%), Gaps = 23/129 (17%)
Query: 206 KRSEVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTN 265
K+ EV +EV + +E K+PKK+ KK+ P EV K ++ + E
Sbjct: 676 KKEEVKKEVKKEIKKEEKKEPKKEVKKETPPK-EVKKEVKK--EEKKEVKKE-------- 724
Query: 266 NANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEEAEFTPPL 325
E+EPKK+ KK + P+ + + + KK++ K A
Sbjct: 725 ------EKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVA------ 772
Query: 326 KCSPKRKGK 334
PK KGK
Sbjct: 773 AGKPKEKGK 781
Score = 28.9 bits (63), Expect = 6.8
Identities = 14/53 (26%), Positives = 27/53 (50%), Gaps = 2/53 (3%)
Query: 208 SEVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTK--LADDADDTPMEE 258
S + +E G+E A ++ ++ PE + SG T+ + ++ TPM+E
Sbjct: 1083 SSIHDETLPGGSESEATASDEENREDQPEEFTATSGYTQSTIEISSEPTPMDE 1135
>gi|32130516 serologically defined colon cancer antigen 1 [Homo
sapiens]
Length = 1076
Score = 43.1 bits (100), Expect = 4e-04
Identities = 47/187 (25%), Positives = 88/187 (47%), Gaps = 38/187 (20%)
Query: 175 DELEFEVFRLDSDAAGVFCIRGK---------LNITSLQFKRSE---VSEEVTENGTEE- 221
DE E+E R D D+ G G+ ++++ LQ +RS S+E + N ++
Sbjct: 750 DEGEYEEVRKDQDSVGEMKDEGEETLNYPDTTIDLSHLQPQRSIQKLASKEESSNSSDSK 809
Query: 222 -------AAKKPKKKKKKKDPETYEVDSGTTKLADDAD---DTPMEESALQNTN-NANGI 270
+AK+ ++ KKKK P DSG + + D ++ + QNT+ N +
Sbjct: 810 SQSRRHLSAKERREMKKKKLPS----DSGDLEALEGKDKEKESTVHIETHQNTSKNVAAV 865
Query: 271 W------EEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEEAEFTPP 324
+ + KK K+K K Q+ +D++ + + S+G + K KK K+ +++ P
Sbjct: 866 QPMKRGQKSKMKKMKEKYKDQDEEDRELIMKLLGSAGSNKEEKGKKGKKGKTKD----EP 921
Query: 325 LKCSPKR 331
+K P++
Sbjct: 922 VKKQPQK 928
>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
[Homo sapiens]
Length = 517
Score = 43.1 bits (100), Expect = 4e-04
Identities = 34/131 (25%), Positives = 61/131 (46%), Gaps = 7/131 (5%)
Query: 209 EVSEEVTENGTEEAAKKPKKKKK----KKDPETYEVDSGTTKLADDADDTPMEESALQNT 264
E+S + ++ EE + PK KKK K + + + +D+DD E +
Sbjct: 215 EMSSDASDASGEEGGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFEGQEVDYM 274
Query: 265 NNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEEAEFTPP 324
++ + +EEP+ K K + +E V + SDSS +S+ +K ++ K EE + P
Sbjct: 275 SDGSSSSQEEPESKAKAPQQEE--GPKGVDEQSDSS-EESEEEKPPEEDKEEEEEKKAPT 331
Query: 325 LKCSPKRKGKS 335
+ +RK S
Sbjct: 332 PQEKKRRKDSS 342
Score = 29.3 bits (64), Expect = 5.2
Identities = 22/107 (20%), Positives = 45/107 (42%), Gaps = 6/107 (5%)
Query: 220 EEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTNNANGIWEEEPKKKK 279
+E K+ + ++K + ++++ +D +D + E + + + KKKK
Sbjct: 190 DEEEKEKRGRRKASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKKKAPLAKGGRKKKK 249
Query: 280 KKKKHQEV--QDQDPVFQGSD----SSGYQSDHKKKKKKRKHSEEAE 320
KK E D F+G + S G S ++ + K K ++ E
Sbjct: 250 KKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEE 296
>gi|125656165 THO complex 2 [Homo sapiens]
Length = 1593
Score = 41.2 bits (95), Expect = 0.001
Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 6/127 (4%)
Query: 208 SEVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTNNA 267
S ++ V EN E+ +K K+KK+K T E L D + P EE A
Sbjct: 1260 SNSNKAVKENDKEKGKEKEKEKKEKTPATTPE----ARVLGKDGKEKPKEERP-NKDEKA 1314
Query: 268 NGIWEEEPKKKKKKKK-HQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEEAEFTPPLK 326
E PK K+K+K +E + +D F+ + + ++++++++ S E + +K
Sbjct: 1315 RETKERTPKSDKEKEKFKKEEKAKDEKFKTTVPNAESKSTQEREREKEPSRERDIAKEMK 1374
Query: 327 CSPKRKG 333
KG
Sbjct: 1375 SKENVKG 1381
Score = 32.0 bits (71), Expect = 0.81
Identities = 22/100 (22%), Positives = 46/100 (46%), Gaps = 7/100 (7%)
Query: 225 KPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTNNANGIWEEEPKKKKKKKKH 284
+P++++K++ +T+ S ++ + D + E SA N+ P K K++
Sbjct: 1402 EPEREQKRRKIDTHPSPSHSSTVKDSLIELK-ESSAKLYINHT------PPPLSKSKERE 1454
Query: 285 QEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEEAEFTPP 324
+ +D D + S + + +K++KR HS PP
Sbjct: 1455 MDKKDLDKSRERSREREKKDEKDRKERKRDHSNNDREVPP 1494
Score = 28.9 bits (63), Expect = 6.8
Identities = 24/117 (20%), Positives = 52/117 (44%), Gaps = 2/117 (1%)
Query: 222 AAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTNNANGIWEEEPKKKKKK 281
A+K + ++ D G + + TP S+ N+ + + +E K+K K
Sbjct: 1216 ASKSDESSTEETDKSRERSQCGVKAVNKASSTTPKGNSSNGNSGSNSNKAVKENDKEKGK 1275
Query: 282 KKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEEAEFTPPLKCSPKR-KGKSNF 337
+K +E +++ P ++ D K+K K+ + +++ + + +PK K K F
Sbjct: 1276 EKEKEKKEKTPATT-PEARVLGKDGKEKPKEERPNKDEKARETKERTPKSDKEKEKF 1331
>gi|56090620 NFKB activating protein-like [Homo sapiens]
Length = 402
Score = 41.2 bits (95), Expect = 0.001
Identities = 32/117 (27%), Positives = 51/117 (43%), Gaps = 9/117 (7%)
Query: 206 KRSEVSEEVTENGTEEA-AKKPKKKKKKKDPET-YEVDSGTTKLADDADDTPMEESALQN 263
+R + E + E G E PK + D T E + T + D+ EE +
Sbjct: 120 RRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKK 179
Query: 264 TNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDH-----KKKKKKRKH 315
T+ + +++ K K K+KH++ D D + +S D KKKKKK+KH
Sbjct: 180 TSRSRN--KKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKH 234
Score = 30.8 bits (68), Expect = 1.8
Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 12/106 (11%)
Query: 209 EVSEEVT-------ENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESAL 261
E EEVT ++ +EE KK + + K + + D+D ++
Sbjct: 155 EDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDT-- 212
Query: 262 QNTNNANGIWEEEPKKKKKKKKH--QEVQDQDPVFQGSDSSGYQSD 305
N+++ + + KKKKKKKKH ++ +++ + SDSS S+
Sbjct: 213 -NSDSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSE 257
>gi|7706254 NOP58 ribonucleoprotein homolog [Homo sapiens]
Length = 529
Score = 40.8 bits (94), Expect = 0.002
Identities = 34/124 (27%), Positives = 63/124 (50%), Gaps = 16/124 (12%)
Query: 217 NGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTNNANGIWEEEPK 276
+GT +A K +K + K + +TY+ +T T ++ ++ + + I E++ K
Sbjct: 407 SGTGKALAKTEKYEHKSEVKTYDPSGDSTL------PTCSKKRKIEQVDKEDEITEKKAK 460
Query: 277 KKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKH------SEEAEFTPPLKCSPK 330
K K K K +E ++++ V + ++S + KKK+ K+KH SEE T SP+
Sbjct: 461 KAKIKVKVEE-EEEEKVAEEEETSVKK---KKKRGKKKHIKEEPLSEEEPCTSTAIASPE 516
Query: 331 RKGK 334
+K K
Sbjct: 517 KKKK 520
Score = 35.4 bits (80), Expect = 0.073
Identities = 20/86 (23%), Positives = 41/86 (47%)
Query: 204 QFKRSEVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQN 263
+ ++ + +E+TE ++A K K ++++++ E ++ K ++E L
Sbjct: 444 KIEQVDKEDEITEKKAKKAKIKVKVEEEEEEKVAEEEETSVKKKKKRGKKKHIKEEPLSE 503
Query: 264 TNNANGIWEEEPKKKKKKKKHQEVQD 289
P+KKKKKKK +E +D
Sbjct: 504 EEPCTSTAIASPEKKKKKKKKRENED 529
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 40.8 bits (94), Expect = 0.002
Identities = 31/116 (26%), Positives = 54/116 (46%), Gaps = 5/116 (4%)
Query: 198 LNITSLQFKRSEVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPME 257
L ++ R V+ + TEN EE K KKKK +K + D+ + +L D D+ +
Sbjct: 67 LEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELED--KDSKSK 124
Query: 258 ESALQNTNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKR 313
++A +G +++ K KK + Q + + GS+ D+ KK K+R
Sbjct: 125 KTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEE---DEDNSKKIKER 177
Score = 37.0 bits (84), Expect = 0.025
Identities = 32/134 (23%), Positives = 54/134 (40%), Gaps = 13/134 (9%)
Query: 200 ITSLQFKRSEVSEEVTENGTEEAAKKPKKKKK-------------KKDPETYEVDSGTTK 246
I ++ K++E E + EE AK K K+K K+ +E ++ +K
Sbjct: 225 IKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSK 284
Query: 247 LADDADDTPMEESALQNTNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDH 306
+ D P E + A E + KKK KKKK E ++++ + S
Sbjct: 285 VTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAM 344
Query: 307 KKKKKKRKHSEEAE 320
++ K K EE +
Sbjct: 345 QEALAKLKEEEERQ 358
Score = 36.2 bits (82), Expect = 0.043
Identities = 32/105 (30%), Positives = 49/105 (46%), Gaps = 8/105 (7%)
Query: 216 ENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDAD--DTPMEESALQNTNNANGIWEE 273
E +++ K KK+KKK+D + ++ +L+ +A E A++ T N EE
Sbjct: 34 EQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENN----EE 89
Query: 274 EPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEE 318
E K KKKK Q+ + Q F +DS + K KK K E
Sbjct: 90 EFTSKDKKKKGQKGKKQS--FDDNDSEELEDKDSKSKKTAKPKVE 132
Score = 33.9 bits (76), Expect = 0.21
Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 22/116 (18%)
Query: 227 KKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTNNANGIWEEEPKK-KKKKKKHQ 285
KK+K K + T DD ++ A + A E+EP+K K KKKK +
Sbjct: 3 KKQKNKSEDST-------------KDDIDLDALAAE-IEGAGAAKEQEPQKSKGKKKKEK 48
Query: 286 EVQ--DQDPVFQ-----GSDSSGYQSDHKKKKKKRKHSEEAEFTPPLKCSPKRKGK 334
+ Q D+D + + ++ G ++D + K + E EFT K +KGK
Sbjct: 49 KKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGK 104
Score = 33.5 bits (75), Expect = 0.28
Identities = 28/129 (21%), Positives = 58/129 (44%), Gaps = 10/129 (7%)
Query: 211 SEEVTENGT----EEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTNN 266
SEE E T + K KK KKKK E E + K A M+E+ +
Sbjct: 295 SEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKE- 353
Query: 267 ANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEEAEFTPPLK 326
EEE +K++++++ + +++ + + + + +KK+K+++ E + L
Sbjct: 354 -----EEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLL 408
Query: 327 CSPKRKGKS 335
+R+ ++
Sbjct: 409 TKSQREARA 417
Score = 32.3 bits (72), Expect = 0.62
Identities = 22/103 (21%), Positives = 45/103 (43%), Gaps = 5/103 (4%)
Query: 215 TENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTNNANGIWEEE 274
++ TE+ + K++PE E + ++ +D EE + + +EE
Sbjct: 511 SDEETEKVEGNKVHIEVKENPEEEEEEE-----EEEEEDEESEEEEEEEGESEGSEGDEE 565
Query: 275 PKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSE 317
+K +K + D+ P + S S Y SD + K++R + +
Sbjct: 566 DEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDK 608
>gi|33356550 G patch domain containing 4 isoform 2 [Homo sapiens]
Length = 370
Score = 40.8 bits (94), Expect = 0.002
Identities = 39/118 (33%), Positives = 55/118 (46%), Gaps = 32/118 (27%)
Query: 220 EEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTNNANGIWEEEPKKKK 279
+ +K PKKKKKK+ + E + T +DAD+ E A QN K KK
Sbjct: 196 QSESKPPKKKKKKRRQK--EEEEATASERNDADE-KHPEHAEQNIR----------KSKK 242
Query: 280 KKKKHQE---VQDQDPVFQGS---DSSG-------------YQSDHKKKKKKRKHSEE 318
KK++HQE +++ +G+ D++G QS K KKKKR H EE
Sbjct: 243 KKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEE 300
Score = 38.1 bits (87), Expect = 0.011
Identities = 29/127 (22%), Positives = 54/127 (42%), Gaps = 16/127 (12%)
Query: 206 KRSEVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTN 265
+R++ E+ E+ + K KKK++ ++ + + GTTK + D S L N
Sbjct: 221 ERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEKED--AAGTSGLGELN 278
Query: 266 NANGIWEEEPKKKKKKKKHQEVQDQDPVFQGS--------------DSSGYQSDHKKKKK 311
+ + K KKKK+ H E + + +G +S Y ++KK
Sbjct: 279 SREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKK 338
Query: 312 KRKHSEE 318
+++ EE
Sbjct: 339 RQQQEEE 345
>gi|33356552 G patch domain containing 4 isoform 1 [Homo sapiens]
Length = 375
Score = 40.8 bits (94), Expect = 0.002
Identities = 39/118 (33%), Positives = 55/118 (46%), Gaps = 32/118 (27%)
Query: 220 EEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTNNANGIWEEEPKKKK 279
+ +K PKKKKKK+ + E + T +DAD+ E A QN K KK
Sbjct: 201 QSESKPPKKKKKKRRQK--EEEEATASERNDADE-KHPEHAEQNIR----------KSKK 247
Query: 280 KKKKHQE---VQDQDPVFQGS---DSSG-------------YQSDHKKKKKKRKHSEE 318
KK++HQE +++ +G+ D++G QS K KKKKR H EE
Sbjct: 248 KKRRHQEGKVSDEREGTTKGNEKEDAAGTSGLGELNSREQTNQSLRKGKKKKRWHHEE 305
Score = 38.1 bits (87), Expect = 0.011
Identities = 29/127 (22%), Positives = 54/127 (42%), Gaps = 16/127 (12%)
Query: 206 KRSEVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTN 265
+R++ E+ E+ + K KKK++ ++ + + GTTK + D S L N
Sbjct: 226 ERNDADEKHPEHAEQNIRKSKKKKRRHQEGKVSDEREGTTKGNEKED--AAGTSGLGELN 283
Query: 266 NANGIWEEEPKKKKKKKKHQEVQDQDPVFQGS--------------DSSGYQSDHKKKKK 311
+ + K KKKK+ H E + + +G +S Y ++KK
Sbjct: 284 SREQTNQSLRKGKKKKRWHHEEEKMGVLEEGGKGKEAAGSVRTEEVESRAYADPCSRRKK 343
Query: 312 KRKHSEE 318
+++ EE
Sbjct: 344 RQQQEEE 350
>gi|33356179 transcription termination factor, RNA polymerase I
[Homo sapiens]
Length = 905
Score = 40.0 bits (92), Expect = 0.003
Identities = 38/142 (26%), Positives = 52/142 (36%), Gaps = 41/142 (28%)
Query: 213 EVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTNNANGIWE 272
E+TE K KKKKKK YE T + + + + +Q + G+ +
Sbjct: 206 EITELPASAHKNKSKKKKKKSSNREYE----TLAMPEGSQAGREAGTDMQESQPTVGLDD 261
Query: 273 EEP------------KKKKKKKKHQE-------------------VQDQDPVF------Q 295
E P KKKKKK HQE +Q+ P
Sbjct: 262 ETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRPAVGLHGETA 321
Query: 296 GSDSSGYQSDHKKKKKKRKHSE 317
G + Y++ KKKKKK H E
Sbjct: 322 GIPAPAYKNKSKKKKKKSNHQE 343
Score = 32.3 bits (72), Expect = 0.62
Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 8/73 (10%)
Query: 224 KKPKKKKKKKDP----ETYEVDSGTTKLADDADDTPMEESALQNTNNANGI----WEEEP 275
KK KKKKKKK E + G+ ++ D A+ GI ++ +
Sbjct: 273 KKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRPAVGLHGETAGIPAPAYKNKS 332
Query: 276 KKKKKKKKHQEVQ 288
KKKKKK HQE +
Sbjct: 333 KKKKKKSNHQEFE 345
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 39.7 bits (91), Expect = 0.004
Identities = 30/125 (24%), Positives = 56/125 (44%), Gaps = 34/125 (27%)
Query: 202 SLQFKRSEVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESAL 261
SL + E EE E EE ++ +++K++++ E +V+
Sbjct: 2242 SLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKE------------------ 2283
Query: 262 QNTNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQ------GSDSSGYQSDHKKKKKKRKH 315
EEE KKKKK+KK +EVQ+++ VF+ + + SD +++++
Sbjct: 2284 ----------EEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSL 2333
Query: 316 SEEAE 320
EE +
Sbjct: 2334 EEEVD 2338
Score = 32.0 bits (71), Expect = 0.81
Identities = 32/139 (23%), Positives = 61/139 (43%), Gaps = 19/139 (13%)
Query: 201 TSLQFKRSEVS-EEVTENGTEEAAKKPKKKKK-KKDPETYEVDSGTTKLADDADDTPMEE 258
+ L K SEV ++ E G EE P K++ +K E D K + D+ EE
Sbjct: 2165 SKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEE 2224
Query: 259 -------SALQNTNNANGIW--EEEPKKKKKKKKHQEVQDQDPVFQGSDSSGY------- 302
S L + EEE ++++++++ +EV++++ + +
Sbjct: 2225 HFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEE 2284
Query: 303 -QSDHKKKKKKRKHSEEAE 320
+ KKK+KK++ +E E
Sbjct: 2285 EEKKKKKKEKKKEEVQEKE 2303
Score = 31.6 bits (70), Expect = 1.1
Identities = 22/87 (25%), Positives = 43/87 (49%), Gaps = 4/87 (4%)
Query: 206 KRSEVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTN 265
+ E E+ E EE KK K+KKK++ E EV ++ + + + + +
Sbjct: 2271 EEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDE--EEEE 2328
Query: 266 NANGIWEEEPKKKK--KKKKHQEVQDQ 290
+ + EE ++K+ KK+K ++Q+Q
Sbjct: 2329 ESCSLEEEVDREKEILKKEKQFKLQEQ 2355
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 39.7 bits (91), Expect = 0.004
Identities = 33/134 (24%), Positives = 54/134 (40%), Gaps = 12/134 (8%)
Query: 215 TENGTEEAAKKPKKKKKKKDPETYEVDSGTTK----------LADDADDTPMEESALQNT 264
T+ ++ K KKK KK PE+ + +SG K A DD + + +
Sbjct: 347 TKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFS 406
Query: 265 NNANGIWEEEPKKK--KKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEEAEFT 322
++ E + +K KK KK + ++ V +S+ S+ K KK K E+
Sbjct: 407 TDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKK 466
Query: 323 PPLKCSPKRKGKSN 336
K K+ K N
Sbjct: 467 DSKKDDKKKDAKKN 480
Score = 37.7 bits (86), Expect = 0.015
Identities = 35/136 (25%), Positives = 54/136 (39%), Gaps = 18/136 (13%)
Query: 198 LNITSLQFKRSEVSEEVTENGTEEAAKKPKKK--KKKKDPETYEVDSGTTKLADDADDTP 255
L + K++E + E G K KKK +PE+ ++ TK ++AD TP
Sbjct: 103 LYTSKTHLKKAEYKKSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNEADKTP 162
Query: 256 MEESALQNTNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKH 315
++ S E E KK K + Q+ + S Q D K K +K
Sbjct: 163 LKSS-----------HENEQSKKSKSSSETNPESQNSKTVSKNCS--QKDKKDSKNSKKT 209
Query: 316 SEEAEFTPPLKCSPKR 331
+ E T K +PK+
Sbjct: 210 NTEFLHT---KNNPKK 222
Score = 35.8 bits (81), Expect = 0.056
Identities = 24/109 (22%), Positives = 42/109 (38%)
Query: 206 KRSEVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTN 265
K+ +V ++ E K ++K KKD + + D + T E ++
Sbjct: 322 KKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDAR 381
Query: 266 NANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRK 314
N + ++ K KKK +++ +S Q D KK KK K
Sbjct: 382 NDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSK 430
Score = 34.7 bits (78), Expect = 0.12
Identities = 30/111 (27%), Positives = 53/111 (47%), Gaps = 16/111 (14%)
Query: 208 SEVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTNNA 267
++ E+ +++ KK KK K + ++ + D +T DAD P +S
Sbjct: 407 TDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEEST----DADSEPKGDSKKGK---- 458
Query: 268 NGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEE 318
++E K KK KK + +D + ++S+ +SD + KK K KHS+E
Sbjct: 459 ----KDEKKGKKDSKKDDKKKDAK---KNAESTEMESDLELKKDK-KHSKE 501
Score = 30.0 bits (66), Expect = 3.1
Identities = 31/149 (20%), Positives = 56/149 (37%), Gaps = 22/149 (14%)
Query: 183 RLDSDAAGVFCIRGKLNITSLQFKRSEVSEEV---------TENGTEEAAKKPKKKKKKK 233
+ +D C LN+ L E + ++N ++ + K K KK
Sbjct: 228 KTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKD 287
Query: 234 DPETYEVDSGTTKLADDADDTPMEESALQNTNNANGIWEEEPKKKKKKKKHQEVQDQDPV 293
+ K + DA+ +++ + + +++ KKK KK E D +
Sbjct: 288 TKKN-------AKKSSDAESEDSKDAKKDSKKVKKNVKKDD--KKKDVKKDTESTDAE-- 336
Query: 294 FQGSDSSGYQSDHKKKKKKRKHSEEAEFT 322
DS + D KK KKK K ++ + T
Sbjct: 337 --SGDSKDERKDTKKDKKKLKKDDKKKDT 363
>gi|34482047 adaptor-related protein complex 3, beta 2 subunit [Homo
sapiens]
Length = 1082
Score = 39.3 bits (90), Expect = 0.005
Identities = 27/113 (23%), Positives = 55/113 (48%), Gaps = 5/113 (4%)
Query: 211 SEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTNNANGI 270
S+ E+G E+A + + + D ++ +SG+ + + ++D+ +E + + +
Sbjct: 679 SDSEGESGPTESADSDPESESESDSKSSS-ESGSGESSSESDNEDQDEDEEKGRGSESEQ 737
Query: 271 WEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEEAEFTP 323
EE+ K+K KKK + + +GSDSS S+ + + SEE + P
Sbjct: 738 SEEDGKRKTKKKVPERKGEASSSDEGSDSSSSSSESEMTSE----SEEEQLEP 786
Score = 35.4 bits (80), Expect = 0.073
Identities = 25/98 (25%), Positives = 48/98 (48%), Gaps = 12/98 (12%)
Query: 227 KKKKKKKDPETY---EVDSGTTKLADDADDTPMEESALQNTNNANGIWEEEPKKKKKKKK 283
++K+K+K+ Y E +SG T+ AD ++ E + ++ + +G + +
Sbjct: 667 REKRKEKEKPFYSDSEGESGPTESADSDPESESESDSKSSSESGSG--------ESSSES 718
Query: 284 HQEVQDQD-PVFQGSDSSGYQSDHKKKKKKRKHSEEAE 320
E QD+D +GS+S + D K+K KK+ + E
Sbjct: 719 DNEDQDEDEEKGRGSESEQSEEDGKRKTKKKVPERKGE 756
>gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo
sapiens]
Length = 1782
Score = 39.3 bits (90), Expect = 0.005
Identities = 25/79 (31%), Positives = 44/79 (55%), Gaps = 5/79 (6%)
Query: 249 DDADDTPMEESALQNTNNANGIWEEEP----KKKKKKKKHQEVQDQD-PVFQGSDSSGYQ 303
DD DD + SAL +T+ + G+ +E P K+K+K+ QEV+ Q+ V SD +
Sbjct: 1702 DDVDDPENQNSALADTDASGGLTKESPDTNGPKQKEKEDAQEVELQEGKVHSESDKAITP 1761
Query: 304 SDHKKKKKKRKHSEEAEFT 322
++ +K+ + S ++E T
Sbjct: 1762 QAQEELQKQERESAKSELT 1780
>gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo
sapiens]
Length = 1684
Score = 39.3 bits (90), Expect = 0.005
Identities = 25/79 (31%), Positives = 44/79 (55%), Gaps = 5/79 (6%)
Query: 249 DDADDTPMEESALQNTNNANGIWEEEP----KKKKKKKKHQEVQDQD-PVFQGSDSSGYQ 303
DD DD + SAL +T+ + G+ +E P K+K+K+ QEV+ Q+ V SD +
Sbjct: 1604 DDVDDPENQNSALADTDASGGLTKESPDTNGPKQKEKEDAQEVELQEGKVHSESDKAITP 1663
Query: 304 SDHKKKKKKRKHSEEAEFT 322
++ +K+ + S ++E T
Sbjct: 1664 QAQEELQKQERESAKSELT 1682
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 39.3 bits (90), Expect = 0.005
Identities = 29/112 (25%), Positives = 62/112 (55%), Gaps = 15/112 (13%)
Query: 205 FKRSEVSEEVTENGTEEA--AKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQ 262
F+ S VSEEV+E+ E+ + KK + +++ +Y+ ++ E+S+ +
Sbjct: 1346 FQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIK------VQEDSSSE 1399
Query: 263 NTNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRK 314
N +N+ EEE ++K+++++ +E ++++ + DS +S K +KK RK
Sbjct: 1400 NKSNS----EEEEEEKEEEEEEEEEEEEEEEDENDDS---KSPGKGRKKIRK 1444
Score = 36.6 bits (83), Expect = 0.033
Identities = 34/143 (23%), Positives = 59/143 (41%), Gaps = 10/143 (6%)
Query: 204 QFKRSEVSEEVTENGTEEAAKKPKKKKKKKD--------PETYEVDSGTTKLADDADDTP 255
+F + + S+E +E+ +++ K ++KKK D + YE S T+ + ++
Sbjct: 929 KFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEIC 988
Query: 256 MEESALQNTNNANGIWEEEPKK--KKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKR 313
++ N E++ KK K KK E+ D G S S+ KK K
Sbjct: 989 HFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGA 1048
Query: 314 KHSEEAEFTPPLKCSPKRKGKSN 336
E+ K S KR+ S+
Sbjct: 1049 YGREKKRCKLLGKSSRKRQDCSS 1071
Score = 35.8 bits (81), Expect = 0.056
Identities = 43/182 (23%), Positives = 81/182 (44%), Gaps = 24/182 (13%)
Query: 153 ASIPKPEQLSAEQWQTMEINMGDELEFEVFRLDSDAAGVFCIRGKLNITSLQFKRSEVSE 212
+S +PE+ + E N GDE +SD+ + + L+ K + VS+
Sbjct: 1253 SSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLT-VSD 1311
Query: 213 EVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQN--------- 263
E+G EE KPK+ K+ K +V S +D++D+ +ES +
Sbjct: 1312 G--ESG-EEKKTKPKEHKEVKGRNRRKVSS------EDSEDSDFQESGVSEEVSESEDEQ 1362
Query: 264 ---TNNANGIWEEEPKK--KKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEE 318
T +A EE ++ K+KKK+ + +D + +S + + K+++++ + EE
Sbjct: 1363 RPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEE 1422
Query: 319 AE 320
E
Sbjct: 1423 EE 1424
Score = 29.3 bits (64), Expect = 5.2
Identities = 23/114 (20%), Positives = 53/114 (46%), Gaps = 13/114 (11%)
Query: 199 NITSLQFKRSEVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTP--- 255
N S + K+ +V E+ + E ++++++K+ E E + + D+ DD+
Sbjct: 1377 NQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPG 1436
Query: 256 ---------MEESALQNTNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSS 300
+++ L+ T N + EEE ++K+ ++ +E + V + D+S
Sbjct: 1437 KGRKKIRKILKDDKLR-TETQNALKEEEERRKRIAEREREREKLREVIEIEDAS 1489
Score = 28.5 bits (62), Expect = 8.9
Identities = 17/77 (22%), Positives = 32/77 (41%), Gaps = 4/77 (5%)
Query: 198 LNITSLQFKRSEVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPME 257
+N + + S + ++ EN EE +K K + S TK + D+ P++
Sbjct: 40 MNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLD 99
Query: 258 ESAL----QNTNNANGI 270
+ + N N+ N I
Sbjct: 100 DETVNEDASNENSENDI 116
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 39.3 bits (90), Expect = 0.005
Identities = 29/112 (25%), Positives = 62/112 (55%), Gaps = 15/112 (13%)
Query: 205 FKRSEVSEEVTENGTEEA--AKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQ 262
F+ S VSEEV+E+ E+ + KK + +++ +Y+ ++ E+S+ +
Sbjct: 1384 FQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIK------VQEDSSSE 1437
Query: 263 NTNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRK 314
N +N+ EEE ++K+++++ +E ++++ + DS +S K +KK RK
Sbjct: 1438 NKSNS----EEEEEEKEEEEEEEEEEEEEEEDENDDS---KSPGKGRKKIRK 1482
Score = 36.6 bits (83), Expect = 0.033
Identities = 34/143 (23%), Positives = 59/143 (41%), Gaps = 10/143 (6%)
Query: 204 QFKRSEVSEEVTENGTEEAAKKPKKKKKKKD--------PETYEVDSGTTKLADDADDTP 255
+F + + S+E +E+ +++ K ++KKK D + YE S T+ + ++
Sbjct: 967 KFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEIC 1026
Query: 256 MEESALQNTNNANGIWEEEPKK--KKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKR 313
++ N E++ KK K KK E+ D G S S+ KK K
Sbjct: 1027 HFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGA 1086
Query: 314 KHSEEAEFTPPLKCSPKRKGKSN 336
E+ K S KR+ S+
Sbjct: 1087 YGREKKRCKLLGKSSRKRQDCSS 1109
Score = 35.8 bits (81), Expect = 0.056
Identities = 43/182 (23%), Positives = 81/182 (44%), Gaps = 24/182 (13%)
Query: 153 ASIPKPEQLSAEQWQTMEINMGDELEFEVFRLDSDAAGVFCIRGKLNITSLQFKRSEVSE 212
+S +PE+ + E N GDE +SD+ + + L+ K + VS+
Sbjct: 1291 SSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLT-VSD 1349
Query: 213 EVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQN--------- 263
E+G EE KPK+ K+ K +V S +D++D+ +ES +
Sbjct: 1350 G--ESG-EEKKTKPKEHKEVKGRNRRKVSS------EDSEDSDFQESGVSEEVSESEDEQ 1400
Query: 264 ---TNNANGIWEEEPKK--KKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEE 318
T +A EE ++ K+KKK+ + +D + +S + + K+++++ + EE
Sbjct: 1401 RPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEE 1460
Query: 319 AE 320
E
Sbjct: 1461 EE 1462
Score = 29.3 bits (64), Expect = 5.2
Identities = 25/121 (20%), Positives = 48/121 (39%), Gaps = 5/121 (4%)
Query: 198 LNITSLQFKRSEVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPME 257
+N + + S + ++ EN EE +K K + S TK + D+ P++
Sbjct: 40 MNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLD 99
Query: 258 ESAL----QNTNNANGIWEEEPKKKKKKKKHQEVQDQD-PVFQGSDSSGYQSDHKKKKKK 312
+ + N N+ N I + K + + V ++D F+G + + KK
Sbjct: 100 DETVNEDASNENSENDITMQSLPKGTVIVQPEPVLNEDKDDFKGPEFRSRSKMKTENLKK 159
Query: 313 R 313
R
Sbjct: 160 R 160
Score = 29.3 bits (64), Expect = 5.2
Identities = 23/114 (20%), Positives = 53/114 (46%), Gaps = 13/114 (11%)
Query: 199 NITSLQFKRSEVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTP--- 255
N S + K+ +V E+ + E ++++++K+ E E + + D+ DD+
Sbjct: 1415 NQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPG 1474
Query: 256 ---------MEESALQNTNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSS 300
+++ L+ T N + EEE ++K+ ++ +E + V + D+S
Sbjct: 1475 KGRKKIRKILKDDKLR-TETQNALKEEEERRKRIAEREREREKLREVIEIEDAS 1527
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 39.3 bits (90), Expect = 0.005
Identities = 35/136 (25%), Positives = 58/136 (42%), Gaps = 34/136 (25%)
Query: 217 NGTEEAAKKPKKKKKKK-----------DPE-TYEVDSGTTKL----------------- 247
+G + AA+ P+ KKKKK PE T G K
Sbjct: 1274 SGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLG 1333
Query: 248 ADDADDTPMEE-----SALQNTNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGY 302
+ A D P EE ++ + +N ++E KK K+KK +E +++ + + +
Sbjct: 1334 SQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDS 1393
Query: 303 QSDHKKKKKKRKHSEE 318
+S +KKKKK+K + E
Sbjct: 1394 ESPSQKKKKKKKKTAE 1409
Score = 29.3 bits (64), Expect = 5.2
Identities = 29/98 (29%), Positives = 41/98 (41%), Gaps = 17/98 (17%)
Query: 195 RGKLNITSLQFKRSEVSEEV-----TENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLAD 249
+GK ++ S Q + E EE+ T G +++ K KK+KKK D + + K
Sbjct: 1327 KGKGSLGS-QGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKA 1385
Query: 250 DADDTPMEESALQNTNNANGIWEEEPKKKKKKKKHQEV 287
T ES Q + KKKKKK Q V
Sbjct: 1386 KKASTKDSESPSQ-----------KKKKKKKKTAEQTV 1412
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 39.3 bits (90), Expect = 0.005
Identities = 35/136 (25%), Positives = 58/136 (42%), Gaps = 34/136 (25%)
Query: 217 NGTEEAAKKPKKKKKKK-----------DPE-TYEVDSGTTKL----------------- 247
+G + AA+ P+ KKKKK PE T G K
Sbjct: 1313 SGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLG 1372
Query: 248 ADDADDTPMEE-----SALQNTNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGY 302
+ A D P EE ++ + +N ++E KK K+KK +E +++ + + +
Sbjct: 1373 SQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDS 1432
Query: 303 QSDHKKKKKKRKHSEE 318
+S +KKKKK+K + E
Sbjct: 1433 ESPSQKKKKKKKKTAE 1448
Score = 29.3 bits (64), Expect = 5.2
Identities = 29/98 (29%), Positives = 41/98 (41%), Gaps = 17/98 (17%)
Query: 195 RGKLNITSLQFKRSEVSEEV-----TENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLAD 249
+GK ++ S Q + E EE+ T G +++ K KK+KKK D + + K
Sbjct: 1366 KGKGSLGS-QGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKA 1424
Query: 250 DADDTPMEESALQNTNNANGIWEEEPKKKKKKKKHQEV 287
T ES Q + KKKKKK Q V
Sbjct: 1425 KKASTKDSESPSQ-----------KKKKKKKKTAEQTV 1451
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 39.3 bits (90), Expect = 0.005
Identities = 35/136 (25%), Positives = 58/136 (42%), Gaps = 34/136 (25%)
Query: 217 NGTEEAAKKPKKKKKKK-----------DPE-TYEVDSGTTKL----------------- 247
+G + AA+ P+ KKKKK PE T G K
Sbjct: 1350 SGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLG 1409
Query: 248 ADDADDTPMEE-----SALQNTNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGY 302
+ A D P EE ++ + +N ++E KK K+KK +E +++ + + +
Sbjct: 1410 SQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDS 1469
Query: 303 QSDHKKKKKKRKHSEE 318
+S +KKKKK+K + E
Sbjct: 1470 ESPSQKKKKKKKKTAE 1485
Score = 29.3 bits (64), Expect = 5.2
Identities = 29/98 (29%), Positives = 41/98 (41%), Gaps = 17/98 (17%)
Query: 195 RGKLNITSLQFKRSEVSEEV-----TENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLAD 249
+GK ++ S Q + E EE+ T G +++ K KK+KKK D + + K
Sbjct: 1403 KGKGSLGS-QGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKA 1461
Query: 250 DADDTPMEESALQNTNNANGIWEEEPKKKKKKKKHQEV 287
T ES Q + KKKKKK Q V
Sbjct: 1462 KKASTKDSESPSQ-----------KKKKKKKKTAEQTV 1488
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 39.3 bits (90), Expect = 0.005
Identities = 35/136 (25%), Positives = 58/136 (42%), Gaps = 34/136 (25%)
Query: 217 NGTEEAAKKPKKKKKKK-----------DPE-TYEVDSGTTKL----------------- 247
+G + AA+ P+ KKKKK PE T G K
Sbjct: 1273 SGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLG 1332
Query: 248 ADDADDTPMEE-----SALQNTNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGY 302
+ A D P EE ++ + +N ++E KK K+KK +E +++ + + +
Sbjct: 1333 SQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDS 1392
Query: 303 QSDHKKKKKKRKHSEE 318
+S +KKKKK+K + E
Sbjct: 1393 ESPSQKKKKKKKKTAE 1408
Score = 29.3 bits (64), Expect = 5.2
Identities = 29/98 (29%), Positives = 41/98 (41%), Gaps = 17/98 (17%)
Query: 195 RGKLNITSLQFKRSEVSEEV-----TENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLAD 249
+GK ++ S Q + E EE+ T G +++ K KK+KKK D + + K
Sbjct: 1326 KGKGSLGS-QGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKA 1384
Query: 250 DADDTPMEESALQNTNNANGIWEEEPKKKKKKKKHQEV 287
T ES Q + KKKKKK Q V
Sbjct: 1385 KKASTKDSESPSQ-----------KKKKKKKKTAEQTV 1411
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 39.3 bits (90), Expect = 0.005
Identities = 35/136 (25%), Positives = 58/136 (42%), Gaps = 34/136 (25%)
Query: 217 NGTEEAAKKPKKKKKKK-----------DPE-TYEVDSGTTKL----------------- 247
+G + AA+ P+ KKKKK PE T G K
Sbjct: 1312 SGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLG 1371
Query: 248 ADDADDTPMEE-----SALQNTNNANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGY 302
+ A D P EE ++ + +N ++E KK K+KK +E +++ + + +
Sbjct: 1372 SQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDS 1431
Query: 303 QSDHKKKKKKRKHSEE 318
+S +KKKKK+K + E
Sbjct: 1432 ESPSQKKKKKKKKTAE 1447
Score = 29.3 bits (64), Expect = 5.2
Identities = 29/98 (29%), Positives = 41/98 (41%), Gaps = 17/98 (17%)
Query: 195 RGKLNITSLQFKRSEVSEEV-----TENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLAD 249
+GK ++ S Q + E EE+ T G +++ K KK+KKK D + + K
Sbjct: 1365 KGKGSLGS-QGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKA 1423
Query: 250 DADDTPMEESALQNTNNANGIWEEEPKKKKKKKKHQEV 287
T ES Q + KKKKKK Q V
Sbjct: 1424 KKASTKDSESPSQ-----------KKKKKKKKTAEQTV 1450
>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
Length = 237
Score = 39.3 bits (90), Expect = 0.005
Identities = 29/115 (25%), Positives = 53/115 (46%), Gaps = 10/115 (8%)
Query: 206 KRSEVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTN 265
K SE S TE+ ++++ KK KK K + E ++ + K ++D P+ +L +
Sbjct: 131 KSSESSMSETESDSKDSLKKKKKSKDGTEKEK-DIKGLSKKRKMYSEDKPLSSESLSESE 189
Query: 266 NANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEEAE 320
+ EE + KKKK ++++ + + H KKKKK+ S +
Sbjct: 190 -----YIEEVRAKKKKSS----EEREKATEKTKKKKKHKKHSKKKKKKAASSSPD 235
Score = 38.9 bits (89), Expect = 0.007
Identities = 29/115 (25%), Positives = 52/115 (45%), Gaps = 14/115 (12%)
Query: 206 KRSEVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTN 265
K E E +G+E ++KK ++KKK+K ++ S ++ +D + + E
Sbjct: 61 KELEKHREKLLSGSESSSKKRQRKKKEKK-KSGRYSSSSSSSSDSSSSSSDSE------- 112
Query: 266 NANGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEEAE 320
+E+ K+ K++KK + + S++ D KKKKK K E E
Sbjct: 113 ------DEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKE 161
Score = 37.7 bits (86), Expect = 0.015
Identities = 30/128 (23%), Positives = 52/128 (40%), Gaps = 6/128 (4%)
Query: 208 SEVSEEVTENGTEEAAKKPKKKKKKKDPETYEVDSGTTKLADDADDTPMEESALQNTNNA 267
S S + + +E K+ K++KKKK+ +S ++ D+ D+ L+ +
Sbjct: 101 SSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDS------LKKKKKS 154
Query: 268 NGIWEEEPKKKKKKKKHQEVQDQDPVFQGSDSSGYQSDHKKKKKKRKHSEEAEFTPPLKC 327
E+E K KK + + P+ S S + + KKK+ E + T K
Sbjct: 155 KDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEEREKATEKTKK 214
Query: 328 SPKRKGKS 335
K K S
Sbjct: 215 KKKHKKHS 222
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,587,623
Number of Sequences: 37866
Number of extensions: 710464
Number of successful extensions: 6291
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 111
Number of HSP's successfully gapped in prelim test: 348
Number of HSP's that attempted gapping in prelim test: 3835
Number of HSP's gapped (non-prelim): 1770
length of query: 338
length of database: 18,247,518
effective HSP length: 103
effective length of query: 235
effective length of database: 14,347,320
effective search space: 3371620200
effective search space used: 3371620200
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.