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Search of human proteins with 50897278
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50897278 G protein-coupled receptor 139 [Homo sapiens]
(353 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50897278 G protein-coupled receptor 139 [Homo sapiens] 725 0.0
gi|32401433 G protein-coupled receptor 142 [Homo sapiens] 287 1e-77
gi|4502631 chemokine (C-C motif) receptor 1 [Homo sapiens] 80 2e-15
gi|4503175 chemokine (C-X-C motif) receptor 4 isoform b [Homo sa... 77 2e-14
gi|56790927 chemokine (C-X-C motif) receptor 4 isoform a [Homo s... 77 2e-14
gi|149944554 somatostatin receptor 4 [Homo sapiens] 77 2e-14
gi|4557857 somatostatin receptor 1 [Homo sapiens] 75 1e-13
gi|30581170 CC chemokine receptor 3 [Homo sapiens] 74 2e-13
gi|4502637 CC chemokine receptor 3 [Homo sapiens] 74 2e-13
gi|170932505 neuromedin U receptor 2 [Homo sapiens] 74 3e-13
gi|4505513 opiate receptor-like 1 [Homo sapiens] 73 3e-13
gi|33286424 opiate receptor-like 1 [Homo sapiens] 73 3e-13
gi|4502455 bombesin-like receptor 3 [Homo sapiens] 72 8e-13
gi|63477962 opioid receptor, delta 1 [Homo sapiens] 69 6e-12
gi|4885121 chemokine (C-C motif) receptor 8 [Homo sapiens] 69 6e-12
gi|154091328 chemokine (C-C motif) receptor 5 [Homo sapiens] 67 2e-11
gi|4502639 chemokine (C-C motif) receptor 5 [Homo sapiens] 67 2e-11
gi|20544172 bradykinin receptor B1 [Homo sapiens] 66 4e-11
gi|4885361 gastrin-releasing peptide receptor [Homo sapiens] 66 5e-11
gi|239757761 PREDICTED: similar to gastrin-releasing peptide rec... 66 5e-11
gi|4826706 EBV-induced G protein-coupled receptor 2 [Homo sapiens] 65 7e-11
gi|161484640 neuromedin B receptor [Homo sapiens] 65 7e-11
gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens] 65 9e-11
gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens] 65 9e-11
gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens] 65 9e-11
gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens] 65 9e-11
gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens] 65 9e-11
gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens] 65 9e-11
gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens] 65 9e-11
gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens] 65 9e-11
>gi|50897278 G protein-coupled receptor 139 [Homo sapiens]
Length = 353
Score = 725 bits (1872), Expect = 0.0
Identities = 353/353 (100%), Positives = 353/353 (100%)
Query: 1 MEHTHAHLAANSSLSWWSPGSACGLGFVPVVYYSLLLCLGLPANILTVIILSQLVARRQK 60
MEHTHAHLAANSSLSWWSPGSACGLGFVPVVYYSLLLCLGLPANILTVIILSQLVARRQK
Sbjct: 1 MEHTHAHLAANSSLSWWSPGSACGLGFVPVVYYSLLLCLGLPANILTVIILSQLVARRQK 60
Query: 61 SSYNYLLALAAADILVLFFIVFVDFLLEDFILNMQMPQVPDKIIEVLEFSSIHTSIWITV 120
SSYNYLLALAAADILVLFFIVFVDFLLEDFILNMQMPQVPDKIIEVLEFSSIHTSIWITV
Sbjct: 61 SSYNYLLALAAADILVLFFIVFVDFLLEDFILNMQMPQVPDKIIEVLEFSSIHTSIWITV 120
Query: 121 PLTIDRYIAVCHPLKYHTVSYPARTRKVIVSVYITCFLTSIPYYWWPNIWTEDYISTSVH 180
PLTIDRYIAVCHPLKYHTVSYPARTRKVIVSVYITCFLTSIPYYWWPNIWTEDYISTSVH
Sbjct: 121 PLTIDRYIAVCHPLKYHTVSYPARTRKVIVSVYITCFLTSIPYYWWPNIWTEDYISTSVH 180
Query: 181 HVLIWIHCFTVYLVPCSIFFILNSIIVYKLRRKSNFRLRGYSTGKTTAILFTITSIFATL 240
HVLIWIHCFTVYLVPCSIFFILNSIIVYKLRRKSNFRLRGYSTGKTTAILFTITSIFATL
Sbjct: 181 HVLIWIHCFTVYLVPCSIFFILNSIIVYKLRRKSNFRLRGYSTGKTTAILFTITSIFATL 240
Query: 241 WAPRIIMILYHLYGAPIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFRTMAAATL 300
WAPRIIMILYHLYGAPIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFRTMAAATL
Sbjct: 241 WAPRIIMILYHLYGAPIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFRTMAAATL 300
Query: 301 KAFFKCQKQPVQFYTNHNFSITSSPWISPANSHCIKMLVYQYDKNGKPIKVSP 353
KAFFKCQKQPVQFYTNHNFSITSSPWISPANSHCIKMLVYQYDKNGKPIKVSP
Sbjct: 301 KAFFKCQKQPVQFYTNHNFSITSSPWISPANSHCIKMLVYQYDKNGKPIKVSP 353
>gi|32401433 G protein-coupled receptor 142 [Homo sapiens]
Length = 462
Score = 287 bits (734), Expect = 1e-77
Identities = 133/287 (46%), Positives = 190/287 (66%), Gaps = 2/287 (0%)
Query: 21 SACGLGFVPVVYYSLLLCLGLPANILTVIILSQLVARRQKSSYNYLLALAAADILVLFFI 80
S C G +PV+YYS+LL LGLP ++LT + L++L R ++ SY YLLAL A+DI++ I
Sbjct: 151 SPCVAGVIPVIYYSVLLGLGLPVSLLTAVALARLATRTRRPSYYYLLALTASDIIIQVVI 210
Query: 81 VFVDFLLEDFILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCHPLKYHTVS 140
VF FLL+ +L Q+PQ + +LEF++ H S+WI + LT+DRY A+CHPL + S
Sbjct: 211 VFAGFLLQGAVLARQVPQAVVRTANILEFAANHASVWIAILLTVDRYTALCHPLHHRAAS 270
Query: 141 YPARTRKVIVSVYITCFLTSIPYYWWPNIWTEDYISTSVHHVLIWIHCFTVYLVPCSIFF 200
P RTR+ I +V LT IP+YWW ++W + ++ VL W HC TVY +PC +F
Sbjct: 271 SPGRTRRAIAAVLSAALLTGIPFYWWLDMWRDTDSPRTLDEVLKWAHCLTVYFIPCGVFL 330
Query: 201 ILNSIIVYKLRRKSNFRLRGYSTGKTTAILFTITSIFATLWAPRIIMILYHLYGAPIQNR 260
+ NS I+++LRR+ L+ GK+TAIL IT++F LWAPR+ ++LYH+Y AP+
Sbjct: 331 VTNSAIIHRLRRRGRSGLQP-RVGKSTAILLGITTLFTLLWAPRVFVMLYHMYVAPVHRD 389
Query: 261 WLVHIMSDIANMLALLNTAINFFLYCFISKRFR-TMAAATLKAFFKC 306
W VH+ D+ANM+A+L+TA NF LYCF+SK FR T+ A+ C
Sbjct: 390 WRVHLALDVANMVAMLHTAANFGLYCFVSKTFRATVRQVIHDAYLPC 436
>gi|4502631 chemokine (C-C motif) receptor 1 [Homo sapiens]
Length = 355
Score = 80.5 bits (197), Expect = 2e-15
Identities = 74/282 (26%), Positives = 135/282 (47%), Gaps = 34/282 (12%)
Query: 33 YSLLLCLGLPANILTVIILSQLVARRQKSSYNYLLALAAADILVLFFIVF-VDFLLEDFI 91
YSL+ +GL NIL V++L Q + +S YLL LA +D+L LF + F +D+ L+D
Sbjct: 41 YSLVFVIGLVGNILVVLVLVQYKRLKNMTSI-YLLNLAISDLLFLFTLPFWIDYKLKD-- 97
Query: 92 LNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCH---PLKYHTVSYPARTRKV 148
+ KI+ ++ +++ I+ + LTIDRY+A+ H L+ TV++ T +
Sbjct: 98 -DWVFGDAMCKILSGFYYTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSII 156
Query: 149 IVSVYITCFLTSIP-YYWWPNIWTEDYISTSVHHVLIWIHCFTVY----------LVPCS 197
I ++ I L S+P Y+ W + + S+H + + ++ ++P
Sbjct: 157 IWALAI---LASMPGLYFSKTQWEFTHHTCSLHFPHESLREWKLFQALKLNLFGLVLPLL 213
Query: 198 IFFILNSIIVYKLRRKSNFRLRGYSTGKTTAILFTITSIFATLWAPRIIMILYHLYGAPI 257
+ I + I+ L R+ N + K ++F I IF W P + IL ++ +
Sbjct: 214 VMIICYTGIIKILLRRPNEK-----KSKAVRLIFVIMIIFFLFWTPYNLTILISVFQDFL 268
Query: 258 ------QNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFR 293
Q+R L + + ++A + +N +Y F+ +RFR
Sbjct: 269 FTHECEQSRHL-DLAVQVTEVIAYTHCCVNPVIYAFVGERFR 309
>gi|4503175 chemokine (C-X-C motif) receptor 4 isoform b [Homo
sapiens]
Length = 352
Score = 77.4 bits (189), Expect = 2e-14
Identities = 72/288 (25%), Positives = 122/288 (42%), Gaps = 24/288 (8%)
Query: 27 FVPVVYYSLLLCLGLPANILTVIILSQLVARRQKSSYNYLLALAAADILVLFFIVFVDFL 86
F+P +Y S++ G+ N L ++++ R + Y L L+ AD+L F++ + F
Sbjct: 40 FLPTIY-SIIFLTGIVGNGLVILVMGYQKKLRSMTD-KYRLHLSVADLL---FVITLPFW 94
Query: 87 LEDFILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCHPLKYHTVSYPARTR 146
D + N K + V+ ++++S+ I +++DRY+A+ H +
Sbjct: 95 AVDAVANWYFGNFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEK 154
Query: 147 KVIVSVYITCFLTSIPYYWWPNIWTED--YISTSVHHVLIWI------HCFTVYLVPCSI 198
V V V+I L +IP + + N+ D YI + +W+ H ++P +
Sbjct: 155 VVYVGVWIPALLLTIPDFIFANVSEADDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIV 214
Query: 199 FFILNSIIVYKLRRKSNFRLRGYSTGKTTAILFTITSIFATLWAPRII------MILYHL 252
II+ KL + R KTT IL I + FA W P I IL +
Sbjct: 215 ILSCYCIIISKLSHSKGHQKR--KALKTTVIL--ILAFFA-CWLPYYIGISIDSFILLEI 269
Query: 253 YGAPIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFRTMAAATL 300
+ VH I LA + +N LY F+ +F+T A L
Sbjct: 270 IKQGCEFENTVHKWISITEALAFFHCCLNPILYAFLGAKFKTSAQHAL 317
>gi|56790927 chemokine (C-X-C motif) receptor 4 isoform a [Homo
sapiens]
Length = 356
Score = 77.4 bits (189), Expect = 2e-14
Identities = 72/288 (25%), Positives = 122/288 (42%), Gaps = 24/288 (8%)
Query: 27 FVPVVYYSLLLCLGLPANILTVIILSQLVARRQKSSYNYLLALAAADILVLFFIVFVDFL 86
F+P +Y S++ G+ N L ++++ R + Y L L+ AD+L F++ + F
Sbjct: 44 FLPTIY-SIIFLTGIVGNGLVILVMGYQKKLRSMTD-KYRLHLSVADLL---FVITLPFW 98
Query: 87 LEDFILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCHPLKYHTVSYPARTR 146
D + N K + V+ ++++S+ I +++DRY+A+ H +
Sbjct: 99 AVDAVANWYFGNFLCKAVHVIYTVNLYSSVLILAFISLDRYLAIVHATNSQRPRKLLAEK 158
Query: 147 KVIVSVYITCFLTSIPYYWWPNIWTED--YISTSVHHVLIWI------HCFTVYLVPCSI 198
V V V+I L +IP + + N+ D YI + +W+ H ++P +
Sbjct: 159 VVYVGVWIPALLLTIPDFIFANVSEADDRYICDRFYPNDLWVVVFQFQHIMVGLILPGIV 218
Query: 199 FFILNSIIVYKLRRKSNFRLRGYSTGKTTAILFTITSIFATLWAPRII------MILYHL 252
II+ KL + R KTT IL I + FA W P I IL +
Sbjct: 219 ILSCYCIIISKLSHSKGHQKR--KALKTTVIL--ILAFFA-CWLPYYIGISIDSFILLEI 273
Query: 253 YGAPIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFRTMAAATL 300
+ VH I LA + +N LY F+ +F+T A L
Sbjct: 274 IKQGCEFENTVHKWISITEALAFFHCCLNPILYAFLGAKFKTSAQHAL 321
>gi|149944554 somatostatin receptor 4 [Homo sapiens]
Length = 388
Score = 77.0 bits (188), Expect = 2e-14
Identities = 74/318 (23%), Positives = 143/318 (44%), Gaps = 31/318 (9%)
Query: 19 PGSACGLGFVPVVYYSLLLCL-GLPANILTVIILSQLVARRQKSSYNYLLALAAADILVL 77
PG A G V + L+CL GL N L + ++ + A+ + ++ YLL LA AD L +
Sbjct: 39 PGDARAAGMVAIQCIYALVCLVGLVGNALVIFVILRY-AKMKTATNIYLLNLAVADELFM 97
Query: 78 FFIVFVDFLLEDFILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCHPLKYH 137
+ FV + + V + + ++ ++ TS++ L++DRY+AV HPL+
Sbjct: 98 LSVPFV--ASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAA 155
Query: 138 TVSYPARTRKVIVSVYITCFLTSIPYYWWPNIWTEDYISTSVHHVLIWIH-----CFTVY 192
T P+ + + + V++ L ++P + + +V L W H F VY
Sbjct: 156 TYRRPSVAKLINLGVWLASLLVTLPIAIFADT-RPARGGQAVACNLQWPHPAWSAVFVVY 214
Query: 193 ------LVPCSIFFILNSIIVYKLRR---KSNFRLRGYSTGKTTAILFTITSIFATLWAP 243
L+P + +IV K+R ++ ++ R S K T ++ + +F W P
Sbjct: 215 TFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMP 274
Query: 244 RIIMILYHLYGAPIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFR-------TMA 296
++ L +L+ + ++ ++ +L+ N+ N LY F+S FR +
Sbjct: 275 FYVVQLLNLFVTSLD-----ATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVLCLR 329
Query: 297 AATLKAFFKCQKQPVQFY 314
L+ +++P+ +Y
Sbjct: 330 CCLLEGAGGAEEEPLDYY 347
>gi|4557857 somatostatin receptor 1 [Homo sapiens]
Length = 391
Score = 74.7 bits (182), Expect = 1e-13
Identities = 70/330 (21%), Positives = 148/330 (44%), Gaps = 29/330 (8%)
Query: 1 MEHTHAHLAANSSLSWWSPGSACGLGFVPVVYYSLLLCLGLPANILTVIILSQLVARRQK 60
ME + + N +LS GSA + F+ YS++ +GL N + + ++ + A+ +
Sbjct: 38 MEEPGRNASQNGTLSE-GQGSAILISFI----YSVVCLVGLCGNSMVIYVILRY-AKMKT 91
Query: 61 SSYNYLLALAAADILVLFFIVFVDFLLEDFILNMQMPQVPDKIIEVLEFSSIHTSIWITV 120
++ Y+L LA AD L++ + F+ + + + + +++ ++ ++ TSI+
Sbjct: 92 ATNIYILNLAIADELLMLSVPFL--VTSTLLRHWPFGALLCRLVLSVDAVNMFTSIYCLT 149
Query: 121 PLTIDRYIAVCHPLKYHTVSYPARTRKVIVSVYITCFLTSIPYYWWPNIWTEDYISTSVH 180
L++DRY+AV HP+K P + V + V++ L +P + + + +
Sbjct: 150 VLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLVILPIVVFSRTAANSDGTVACN 209
Query: 181 HVL-----IWIHCFTVY------LVPCSIFFILNSIIVYKLRR---KSNFRLRGYSTGKT 226
++ W+ F +Y L+P + +I+ K+R K+ ++ R S K
Sbjct: 210 MLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMVALKAGWQQRKRSERKI 269
Query: 227 TAILFTITSIFATLWAPRIIMILYHLYGAPIQNRWLVHIMSDIANMLALLNTAINFFLYC 286
T ++ + +F W P ++ L +++ +S ++ +L N+ N LY
Sbjct: 270 TLMVMMVVMVFVICWMPFYVVQLVNVFAEQDD-----ATVSQLSVILGYANSCANPILYG 324
Query: 287 FISKRFRT--MAAATLKAFFKCQKQPVQFY 314
F+S F+ L ++PV +Y
Sbjct: 325 FLSDNFKRSFQRILCLSWMDNAAEEPVDYY 354
>gi|30581170 CC chemokine receptor 3 [Homo sapiens]
Length = 355
Score = 74.3 bits (181), Expect = 2e-13
Identities = 71/279 (25%), Positives = 125/279 (44%), Gaps = 17/279 (6%)
Query: 27 FVPVVYYSLLLCLGLPANILTVIILSQLVARRQKSSYN-YLLALAAADILVLFFIVFVDF 85
FVP +Y SL+ +GL N++ V+IL + RR + N YLL LA +D+L L + F
Sbjct: 36 FVPPLY-SLVFTVGLLGNVVVVMILIKY--RRLRIMTNIYLLNLAISDLLFLVTLPFWIH 92
Query: 86 LLEDFILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCH---PLKYHTVSYP 142
+ N K++ + +++ I+ + LTIDRY+A+ H L+ TV++
Sbjct: 93 YVRGH--NWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFG 150
Query: 143 ARTRKVIVSVYITCFLTSIPYYWWPNIWTEDYISTSVHH--VLIWIHCFTVYL-VPCSIF 199
T V + + L +Y ++ E S V W H T+ + + C +
Sbjct: 151 VITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVL 210
Query: 200 FILNSIIVYKLRRKSNFRLRGYSTGKTTAILFTITSIFATLWAPRIIMILYH-----LYG 254
+L I Y K+ R K ++F I ++F W P + IL L+G
Sbjct: 211 PLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFG 270
Query: 255 APIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFR 293
+ + ++ + ++A + +N +Y F+ +RFR
Sbjct: 271 NDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFR 309
>gi|4502637 CC chemokine receptor 3 [Homo sapiens]
Length = 355
Score = 74.3 bits (181), Expect = 2e-13
Identities = 71/279 (25%), Positives = 125/279 (44%), Gaps = 17/279 (6%)
Query: 27 FVPVVYYSLLLCLGLPANILTVIILSQLVARRQKSSYN-YLLALAAADILVLFFIVFVDF 85
FVP +Y SL+ +GL N++ V+IL + RR + N YLL LA +D+L L + F
Sbjct: 36 FVPPLY-SLVFTVGLLGNVVVVMILIKY--RRLRIMTNIYLLNLAISDLLFLVTLPFWIH 92
Query: 86 LLEDFILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCH---PLKYHTVSYP 142
+ N K++ + +++ I+ + LTIDRY+A+ H L+ TV++
Sbjct: 93 YVRGH--NWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFG 150
Query: 143 ARTRKVIVSVYITCFLTSIPYYWWPNIWTEDYISTSVHH--VLIWIHCFTVYL-VPCSIF 199
T V + + L +Y ++ E S V W H T+ + + C +
Sbjct: 151 VITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVL 210
Query: 200 FILNSIIVYKLRRKSNFRLRGYSTGKTTAILFTITSIFATLWAPRIIMILYH-----LYG 254
+L I Y K+ R K ++F I ++F W P + IL L+G
Sbjct: 211 PLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFG 270
Query: 255 APIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFR 293
+ + ++ + ++A + +N +Y F+ +RFR
Sbjct: 271 NDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFR 309
>gi|170932505 neuromedin U receptor 2 [Homo sapiens]
Length = 415
Score = 73.6 bits (179), Expect = 3e-13
Identities = 75/326 (23%), Positives = 152/326 (46%), Gaps = 50/326 (15%)
Query: 27 FVPV-VYYSLLLCLGLPANILTVIILSQLVARRQKSSYNYLLALAAADILVLFF----IV 81
F+PV V Y + +G+ N+L +++ Q A + ++Y YL +LA +D+LVL V
Sbjct: 45 FLPVSVVYVPIFVVGVIGNVLVCLVILQHQAMKTPTNY-YLFSLAVSDLLVLLLGMPLEV 103
Query: 82 FVDFLLEDFILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCHPLKYHTVSY 141
+ + F+ + E + F+SI + IT ++++RY+A+ HP + S
Sbjct: 104 YEMWRNYPFLFGPVGCYFKTALFETVCFASI---LSITT-VSVERYVAILHPFRAKLQST 159
Query: 142 PARTRKVIVSVYITCFLTSIP--------YYWWPNIWTEDYISTS-------VHHVLIWI 186
R +++ V+ L S+P ++++PN +T +++ +I +
Sbjct: 160 RRRALRILGIVWGFSVLFSLPNTSIHGIKFHYFPNGSLVPGSATCTVIKPMWIYNFIIQV 219
Query: 187 HCFTVYLVPCSIFFILNSIIVYKLRR-------KSNFRLRGYSTGKTTAILFTITSIFAT 239
F YL+P ++ +L ++ +L++ + N ++ +LF + +FA
Sbjct: 220 TSFLFYLLPMTVISVLYYLMALRLKKDKSLEADEGNANIQRPCRKSVNKMLFVLVLVFAI 279
Query: 240 LWAPRIIMILYHLYG-------APIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRF 292
WAP I L+ + A + N LVH++S + L++A+N +Y +S+RF
Sbjct: 280 CWAPFHIDRLFFSFVEEWSESLAAVFN--LVHVVSGV---FFYLSSAVNPIIYNLLSRRF 334
Query: 293 RTMAAATLKAFFKCQKQPVQFYTNHN 318
+ + +F K Q+++ H+
Sbjct: 335 QAAFQNVISSFHK------QWHSQHD 354
>gi|4505513 opiate receptor-like 1 [Homo sapiens]
Length = 370
Score = 73.2 bits (178), Expect = 3e-13
Identities = 70/305 (22%), Positives = 137/305 (44%), Gaps = 30/305 (9%)
Query: 7 HLAANSSLSWWSPGSACGLGF-VPVVYYSLLLCLG-LPANILTVIILSQLVARRQKSSYN 64
HL N+S + P LG V +V L +C+G L N L + ++ L + K++ N
Sbjct: 35 HLLLNASHGAFLP-----LGLKVTIVGLYLAVCVGGLLGNCLVMYVI--LRHTKMKTATN 87
Query: 65 -YLLALAAADILVLFFIVF--VDFLLEDFILNMQMPQVPDKIIEVLEFSSIHTSIWITVP 121
Y+ LA AD LVL + F D LL + + K + +++ ++ TS +
Sbjct: 88 IYIFNLALADTLVLLTLPFQGTDILLGFWPFGNALC----KTVIAIDYYNMFTSTFTLTA 143
Query: 122 LTIDRYIAVCHPLKYHTVSYPARTRKVIVSVYITCFLTSIPYYWWPNIWTEDYISTSVHH 181
+++DRY+A+CHP++ V ++ + V V+++ + +P + ED +
Sbjct: 144 MSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVE 203
Query: 182 VL----IWIHCFTV------YLVPCSIFFILNSIIVYKL---RRKSNFRLRGYSTGKTTA 228
+ W F + ++VP + + S+++ +L R S R + + + T
Sbjct: 204 IPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIRRLRGVRLLSGSREKDRNLRRITR 263
Query: 229 ILFTITSIFATLWAPRIIMILYHLYGAPIQNRWLVHIMSDIANMLALLNTAINFFLYCFI 288
++ + ++F W P + +L G + V I+ L +N+ +N LY F+
Sbjct: 264 LVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAILR-FCTALGYVNSCLNPILYAFL 322
Query: 289 SKRFR 293
+ F+
Sbjct: 323 DENFK 327
>gi|33286424 opiate receptor-like 1 [Homo sapiens]
Length = 370
Score = 73.2 bits (178), Expect = 3e-13
Identities = 70/305 (22%), Positives = 137/305 (44%), Gaps = 30/305 (9%)
Query: 7 HLAANSSLSWWSPGSACGLGF-VPVVYYSLLLCLG-LPANILTVIILSQLVARRQKSSYN 64
HL N+S + P LG V +V L +C+G L N L + ++ L + K++ N
Sbjct: 35 HLLLNASHGAFLP-----LGLKVTIVGLYLAVCVGGLLGNCLVMYVI--LRHTKMKTATN 87
Query: 65 -YLLALAAADILVLFFIVF--VDFLLEDFILNMQMPQVPDKIIEVLEFSSIHTSIWITVP 121
Y+ LA AD LVL + F D LL + + K + +++ ++ TS +
Sbjct: 88 IYIFNLALADTLVLLTLPFQGTDILLGFWPFGNALC----KTVIAIDYYNMFTSTFTLTA 143
Query: 122 LTIDRYIAVCHPLKYHTVSYPARTRKVIVSVYITCFLTSIPYYWWPNIWTEDYISTSVHH 181
+++DRY+A+CHP++ V ++ + V V+++ + +P + ED +
Sbjct: 144 MSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVE 203
Query: 182 VL----IWIHCFTV------YLVPCSIFFILNSIIVYKL---RRKSNFRLRGYSTGKTTA 228
+ W F + ++VP + + S+++ +L R S R + + + T
Sbjct: 204 IPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIRRLRGVRLLSGSREKDRNLRRITR 263
Query: 229 ILFTITSIFATLWAPRIIMILYHLYGAPIQNRWLVHIMSDIANMLALLNTAINFFLYCFI 288
++ + ++F W P + +L G + V I+ L +N+ +N LY F+
Sbjct: 264 LVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAILR-FCTALGYVNSCLNPILYAFL 322
Query: 289 SKRFR 293
+ F+
Sbjct: 323 DENFK 327
>gi|4502455 bombesin-like receptor 3 [Homo sapiens]
Length = 399
Score = 72.0 bits (175), Expect = 8e-13
Identities = 72/315 (22%), Positives = 146/315 (46%), Gaps = 36/315 (11%)
Query: 17 WSPGSACGLGFVPVVY--YSLLLCLGLPANILTVIILSQLVARRQKSSYNYLLALAAADI 74
WS ++ G+ + +Y Y++++ +G+ N + + + + + + + ++ +LA D+
Sbjct: 36 WSGDNSPGIEALCAIYITYAVIISVGILGNAILIKVFFKTKSMQTVPNI-FITSLAFGDL 94
Query: 75 LVLFFIVFVD---FLLEDFILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVC 131
L+L V VD +L E ++ ++ K++ + +S+ S++ L+ DRY AV
Sbjct: 95 LLLLTCVPVDATHYLAEGWLFG----RIGCKVLSFIRLTSVGVSVFTLTILSADRYKAVV 150
Query: 132 HPLKYHTVSYPARTRKVIVSVYITCFLTSIPYYWWPNIWT----------EDYISTSVHH 181
PL+ + +T V+I + ++P + N++T E S V
Sbjct: 151 KPLERQPSNAILKTCVKAGCVWIVSMIFALPEAIFSNVYTFRDPNKNMTFESCTSYPVSK 210
Query: 182 VLIW-IH---CFTV-YLVPCSIFFILNSII---VYK------LRRKSNFRLRGYSTGKTT 227
L+ IH CF V Y++P SI + S+I +YK +S+ R + S +
Sbjct: 211 KLLQEIHSLLCFLVFYIIPLSIISVYYSLIARTLYKSTLNIPTEEQSHARKQIESRKRIA 270
Query: 228 AILFTITSIFATLWAPRIIMILYHLYGAP--IQNRWLVHIMSDIANMLALLNTAINFFLY 285
+ + ++FA W P ++ LYH + + + + I + + +LA N+ +N F
Sbjct: 271 RTVLVLVALFALCWLPNHLLYLYHSFTSQTYVDPSAMHFIFTIFSRVLAFSNSCVNPFAL 330
Query: 286 CFISKRFRTMAAATL 300
++SK F+ A L
Sbjct: 331 YWLSKSFQKHFKAQL 345
>gi|63477962 opioid receptor, delta 1 [Homo sapiens]
Length = 372
Score = 68.9 bits (167), Expect = 6e-12
Identities = 60/290 (20%), Positives = 130/290 (44%), Gaps = 24/290 (8%)
Query: 21 SACGLGFVPVVYYSLLLCLGLPANILTVIILSQLVARRQKSSYN-YLLALAAADILVLFF 79
S+ L YS + +GL N+L + + + + K++ N Y+ LA AD L
Sbjct: 44 SSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYT--KMKTATNIYIFNLALADALATST 101
Query: 80 IVF--VDFLLEDFILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCHPLKYH 137
+ F +L+E + ++ K + +++ ++ TSI+ +++DRYIAVCHP+K
Sbjct: 102 LPFQSAKYLMETWPFG----ELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKAL 157
Query: 138 TVSYPARTRKVIVSVYITCFLTSIPYYWWPNIWTED-------------YISTSVHHVLI 184
PA+ + + + +++ +P D + +V + +
Sbjct: 158 DFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICV 217
Query: 185 WIHCFTVYLVPCSIFFILNSIIVYKLRRKSNFRLRGYSTGKTTAILFTITSIFATLWAP- 243
++ F V ++ ++ + L + + +R S + + S + T ++ + F WAP
Sbjct: 218 FLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPI 277
Query: 244 RIIMILYHLYGAPIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFR 293
I +I++ L ++ +V + + L N+++N LY F+ + F+
Sbjct: 278 HIFVIVWTLVDIDRRDPLVVAAL-HLCIALGYANSSLNPVLYAFLDENFK 326
>gi|4885121 chemokine (C-C motif) receptor 8 [Homo sapiens]
Length = 355
Score = 68.9 bits (167), Expect = 6e-12
Identities = 65/283 (22%), Positives = 132/283 (46%), Gaps = 34/283 (12%)
Query: 31 VYYSLLLCLGLPANILTVIILSQLVARRQKSSYN-YLLALAAADILVLFFIVFVDF-LLE 88
V+Y LL L N L +++L +V ++ +S + YLL LA +D+L +F F + LL+
Sbjct: 40 VFYCLLFVFSLLGNSLVILVL--VVCKKLRSITDVYLLNLALSDLLFVFSFPFQTYYLLD 97
Query: 89 DFILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCHPLKYHTVSYPARTRKV 148
++ M K++ + ++S++ +++DRY+AV H + V +
Sbjct: 98 QWVFGTVMC----KVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTTL 153
Query: 149 IVSVYITCFLTSIPYYWWPNIWTEDYI----STSVHHVLIWIHCFTVY-------LVPCS 197
++V++T + +IP + + +ED + S L W FT + L+P +
Sbjct: 154 CLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKW-KIFTNFKMNILGLLIPFT 212
Query: 198 IFFILNSIIVYKLRRKSNFRLRGYSTGKTTAILFTITSIFATL--WAP-RIIMILYHLYG 254
IF I+++L+R N KT AI + + A+L W P +++ L L+
Sbjct: 213 IFMFCYIKILHQLKRCQNH-------NKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHS 265
Query: 255 APIQNRWLVH----IMSDIANMLALLNTAINFFLYCFISKRFR 293
I + + + + +++ + +N +Y F+ ++F+
Sbjct: 266 MHILDGCSISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFK 308
>gi|154091328 chemokine (C-C motif) receptor 5 [Homo sapiens]
Length = 352
Score = 67.4 bits (163), Expect = 2e-11
Identities = 76/297 (25%), Positives = 122/297 (41%), Gaps = 33/297 (11%)
Query: 33 YSLLLCLGLPANILTVIILSQLVARRQKSSYN-YLLALAAADILVLFFIVFVDFLLEDFI 91
YSL+ G N+L ++IL + +R KS + YLL LA +D LFF++ V F
Sbjct: 37 YSLVFIFGFVGNMLVILIL--INCKRLKSMTDIYLLNLAISD---LFFLLTVPFWAHYAA 91
Query: 92 LNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCH---PLKYHTVSYPARTRKV 148
+++ L F + I+ + LTIDRY+AV H LK TV++ T
Sbjct: 92 AQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTS-- 149
Query: 149 IVSVYITCFLTSIPYYWWPNIWTEDYISTSVHH-----VLIWIHCFTVYLVPCSIFF-IL 202
V ++ S+P + E T H W + T+ +V + +L
Sbjct: 150 -VITWVVAVFASLPGIIFTRSQKEGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLL 208
Query: 203 NSIIVYKLRRKSNFRLRG-YSTGKTTAILFTITSIFATLWAPRIIMIL-------YHLYG 254
+I Y K+ R R + ++FTI ++ WAP I++L + L
Sbjct: 209 VMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNN 268
Query: 255 APIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFRTMAAA-----TLKAFFKC 306
NR + + L + + IN +Y F+ ++FR K F KC
Sbjct: 269 CSSSNR--LDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKC 323
>gi|4502639 chemokine (C-C motif) receptor 5 [Homo sapiens]
Length = 352
Score = 67.4 bits (163), Expect = 2e-11
Identities = 76/297 (25%), Positives = 122/297 (41%), Gaps = 33/297 (11%)
Query: 33 YSLLLCLGLPANILTVIILSQLVARRQKSSYN-YLLALAAADILVLFFIVFVDFLLEDFI 91
YSL+ G N+L ++IL + +R KS + YLL LA +D LFF++ V F
Sbjct: 37 YSLVFIFGFVGNMLVILIL--INCKRLKSMTDIYLLNLAISD---LFFLLTVPFWAHYAA 91
Query: 92 LNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCH---PLKYHTVSYPARTRKV 148
+++ L F + I+ + LTIDRY+AV H LK TV++ T
Sbjct: 92 AQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTS-- 149
Query: 149 IVSVYITCFLTSIPYYWWPNIWTEDYISTSVHH-----VLIWIHCFTVYLVPCSIFF-IL 202
V ++ S+P + E T H W + T+ +V + +L
Sbjct: 150 -VITWVVAVFASLPGIIFTRSQKEGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLL 208
Query: 203 NSIIVYKLRRKSNFRLRG-YSTGKTTAILFTITSIFATLWAPRIIMIL-------YHLYG 254
+I Y K+ R R + ++FTI ++ WAP I++L + L
Sbjct: 209 VMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNN 268
Query: 255 APIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFRTMAAA-----TLKAFFKC 306
NR + + L + + IN +Y F+ ++FR K F KC
Sbjct: 269 CSSSNR--LDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKC 323
>gi|20544172 bradykinin receptor B1 [Homo sapiens]
Length = 353
Score = 66.2 bits (160), Expect = 4e-11
Identities = 67/276 (24%), Positives = 122/276 (44%), Gaps = 26/276 (9%)
Query: 40 GLPANILTVIILSQLVARRQKSSYN-YLLALAAADILVLFFIVFVDFLLEDFILNMQMP- 97
GL N+ +++ L+ RRQ + YL LAA+D++ F++ + F E+ P
Sbjct: 51 GLLGNLFVLLVF--LLPRRQLNVAEIYLANLAASDLV---FVLGLPFWAENIWNQFNWPF 105
Query: 98 -QVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCHPLKYHTVSYPARTRKVIVSVYITC 156
+ ++I + +++ SI++ V ++ DRY + HP+ + R V +++
Sbjct: 106 GALLCRVINGVIKANLFISIFLVVAISQDRYRVLVHPMASRRQQRRRQARVTCVLIWVVG 165
Query: 157 FLTSIPYYWWPNIWTEDYISTSVHHVLI----WIHCFTV------YLVPCSIFFILNSII 206
L SIP + +I ++ + +L+ W V +L+P + N I
Sbjct: 166 GLLSIPTFLLRSIQAVPDLNITACILLLPHEAWHFARIVELNILGFLLPLAAIVFFNYHI 225
Query: 207 VYKLRRK---SNFRLRGYSTGKTTAILFTITSIFATLWAP-RIIMILYHLYGAPIQNR-- 260
+ LR + S R G KTTA++ T+ F WAP L L+
Sbjct: 226 LASLRTREEVSRTRCGGRKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLFQVQAVRGCF 285
Query: 261 W--LVHIMSDIANMLALLNTAINFFLYCFISKRFRT 294
W + + +AN A N+++N +Y F+ + FRT
Sbjct: 286 WEDFIDLGLQLANFFAFTNSSLNPVIYVFVGRLFRT 321
>gi|4885361 gastrin-releasing peptide receptor [Homo sapiens]
Length = 384
Score = 65.9 bits (159), Expect = 5e-11
Identities = 70/306 (22%), Positives = 134/306 (43%), Gaps = 37/306 (12%)
Query: 16 WWSPGSACGLGFVPVVYYSLLLCLGLPANILTVIILSQLVARRQKSSYNYLLALAAADIL 75
W PG L +P VY +++ +GL NI + I + + R + ++ +LA D+L
Sbjct: 34 WSHPGI---LYVIPAVY-GVIILIGLIGNITLIKIFCTVKSMRNVPNL-FISSLALGDLL 88
Query: 76 VLFFIVFVD---FLLEDFILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCH 132
+L VD +L + ++ ++ K+I ++ +S+ S++ L+ DRY A+
Sbjct: 89 LLITCAPVDASRYLADRWLFG----RIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVR 144
Query: 133 PLKYHTVSYPARTRKVIVSVYITCFLTSIPYYWWPNI-------WTEDYI-------STS 178
P+ + ++I L +IP + ++ + +I S
Sbjct: 145 PMDIQASHALMKICLKAAFIWIISMLLAIPEAVFSDLHPFHEESTNQTFISCAPYPHSNE 204
Query: 179 VHHVLIWIHCFTV-YLVPCSI-----FFILNSII--VYKLRRKSNFRLRGY--STGKTTA 228
+H + + F V Y++P SI +FI ++I Y L + N ++ S +
Sbjct: 205 LHPKIHSMASFLVFYVIPLSIISVYYYFIAKNLIQSAYNLPVEGNIHVKKQIESRKRLAK 264
Query: 229 ILFTITSIFATLWAPRIIMILYHLYGAPIQNRWLVHIMSDI-ANMLALLNTAINFFLYCF 287
+ +FA W P ++ LY Y + ++H ++ I A +LA N+ +N F
Sbjct: 265 TVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLHFVTSICARLLAFTNSCVNPFALYL 324
Query: 288 ISKRFR 293
+SK FR
Sbjct: 325 LSKSFR 330
>gi|239757761 PREDICTED: similar to gastrin-releasing peptide
receptor [Homo sapiens]
Length = 368
Score = 65.9 bits (159), Expect = 5e-11
Identities = 70/306 (22%), Positives = 134/306 (43%), Gaps = 37/306 (12%)
Query: 16 WWSPGSACGLGFVPVVYYSLLLCLGLPANILTVIILSQLVARRQKSSYNYLLALAAADIL 75
W PG L +P VY +++ +GL NI + I + + R + ++ +LA D+L
Sbjct: 18 WSHPGI---LYVIPAVY-GVIILIGLIGNITLIKIFCTVKSMRNVPNL-FISSLALGDLL 72
Query: 76 VLFFIVFVD---FLLEDFILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCH 132
+L VD +L + ++ ++ K+I ++ +S+ S++ L+ DRY A+
Sbjct: 73 LLITCAPVDASRYLADRWLFG----RIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVR 128
Query: 133 PLKYHTVSYPARTRKVIVSVYITCFLTSIPYYWWPNI-------WTEDYI-------STS 178
P+ + ++I L +IP + ++ + +I S
Sbjct: 129 PMDIQASHALMKICLKAAFIWIISMLLAIPEAVFSDLHPFHEESTNQTFISCAPYPHSNE 188
Query: 179 VHHVLIWIHCFTV-YLVPCSI-----FFILNSII--VYKLRRKSNFRLRGY--STGKTTA 228
+H + + F V Y++P SI +FI ++I Y L + N ++ S +
Sbjct: 189 LHPKIHSMASFLVFYVIPLSIISVYYYFIAKNLIQSAYNLPVEGNIHVKKQIESRKRLAK 248
Query: 229 ILFTITSIFATLWAPRIIMILYHLYGAPIQNRWLVHIMSDI-ANMLALLNTAINFFLYCF 287
+ +FA W P ++ LY Y + ++H ++ I A +LA N+ +N F
Sbjct: 249 TVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLHFVTSICARLLAFTNSCVNPFALYL 308
Query: 288 ISKRFR 293
+SK FR
Sbjct: 309 LSKSFR 314
>gi|4826706 EBV-induced G protein-coupled receptor 2 [Homo sapiens]
Length = 361
Score = 65.5 bits (158), Expect = 7e-11
Identities = 74/345 (21%), Positives = 138/345 (40%), Gaps = 47/345 (13%)
Query: 31 VYYSLLLCLGLPANILTVIILSQLVARRQKSSYNYLLALAAADIL--------VLFFIVF 82
++YSL+ +GL N+L ++++ Q ++ S+ Y L +DIL + ++ +
Sbjct: 36 LHYSLVFIIGLVGNLLALVVIVQN-RKKINSTTLYSTNLVISDILFTTALPTRIAYYAMG 94
Query: 83 VDFLLEDFILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCHPLKYHTVSYP 142
D+ + D + +I ++ + + + + L+IDR+IAV HPL+Y+ +
Sbjct: 95 FDWRIGDALC---------RITALVFYINTYAGVNFMTCLSIDRFIAVVHPLRYNKIKRI 145
Query: 143 ARTRKVIVSVYITCFLTSIPYYWWP-------NIWTEDYISTSVHHVLIWI---HCFTVY 192
+ V + V+I F ++P P I +Y + L WI CF Y
Sbjct: 146 EHAKGVCIFVWILVFAQTLPLLINPMSKQEAERITCMEYPNFEETKSLPWILLGACFIGY 205
Query: 193 LVPCSIFFILNSIIVYKLRRKSNFRLRGYSTG---KTTAILFTITSIFATLWAPRIIMIL 249
++P I I S I KL R + +G K + I +F + P + I+
Sbjct: 206 VLPLIIILICYSQICCKLFRTAKQNPLTEKSGVNKKALNTIILIIVVFVLCFTPYHVAII 265
Query: 250 YHLYG-------APIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFRTMAAATLKA 302
H+ R I L N ++ F+Y F K ++ LK
Sbjct: 266 QHMIKKLRFSNFLECSQRHSFQISLHFTVCLMNFNCCMDPFIYFFACKGYKRKVMRMLKR 325
Query: 303 FFKCQKQPVQFYTNHNFSITSSPWISPANSHCIKMLVYQYDKNGK 347
Q + + ++ S+P + +M+++ NGK
Sbjct: 326 ---------QVSVSISSAVKSAPEENSREMTETQMMIHSKSSNGK 361
>gi|161484640 neuromedin B receptor [Homo sapiens]
Length = 390
Score = 65.5 bits (158), Expect = 7e-11
Identities = 70/285 (24%), Positives = 125/285 (43%), Gaps = 26/285 (9%)
Query: 33 YSLLLCLGLPANILTVIILSQLVARRQKSSYNYLLALAAADILVLFFIVFVDFLLEDFIL 92
Y L++ +GL NI+ V I A R + ++ LAA D+L+L V VD F
Sbjct: 50 YLLIITVGLLGNIMLVKIFITNSAMRSVPNI-FISNLAAGDLLLLLTCVPVD-ASRYFFD 107
Query: 93 NMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCHPLKYHTVSYPARTRKVIVSV 152
+V K+I V++ +S+ S++ L+ DRY A+ +P+ T RT + +
Sbjct: 108 EWMFGKVGCKLIPVIQLTSVGVSVFTLTALSADRYRAIVNPMDMQTSGALLRTCVKAMGI 167
Query: 153 YITCFLTSIPYYWWPNIW-----------------TEDYISTSVHHVLIWIHCFTVYLVP 195
++ L ++P + + D + +H VLI++ F + L
Sbjct: 168 WVVSVLLAVPEAVFSEVARISSLDNSSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLAI 227
Query: 196 CSIFF--ILNSII--VYKLRRKSN-FRLRGYSTGKTTA-ILFTITSIFATLWAPRIIMIL 249
SI++ I ++I + L + N + T K A I+ F W P I+ +
Sbjct: 228 ISIYYYHIAKTLIKSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFIFCWFPNHILYM 287
Query: 250 YHLYGAPIQNRWLVH-IMSDIANMLALLNTAINFFLYCFISKRFR 293
Y + + L H I++ +A +L+ N+ +N F +S+ FR
Sbjct: 288 YRSFNYNEIDPSLGHMIVTLVARVLSFGNSCVNPFALYLLSESFR 332
>gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]
Length = 493
Score = 65.1 bits (157), Expect = 9e-11
Identities = 63/278 (22%), Positives = 123/278 (44%), Gaps = 25/278 (8%)
Query: 33 YSLLLCLGLPANILTVIILSQLVARRQKSSYN-YLLALAAADILVLFFIVF--VDFLLED 89
YS++ +GL N L + ++ + + K++ N Y+ LA AD L + F V++L+
Sbjct: 170 YSIVCVVGLFGNFLVMYVIVRYT--KMKTATNIYIFNLALADALATSTLPFQSVNYLMGT 227
Query: 90 FILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCHPLKYHTVSYPARTRKVI 149
+ + KI+ +++ ++ TSI+ +++DRYIAVCHP+K P + +
Sbjct: 228 WPFGT----ILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIIN 283
Query: 150 VSVYITCFLTSIPYYWWPNI----WTEDYISTSVHHVLIWIHCFTV------YLVPCSIF 199
V +I +P + + D T H W + + +++P I
Sbjct: 284 VCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLII 343
Query: 200 FILNSIIVYKL---RRKSNFRLRGYSTGKTTAILFTITSIFATLWAP-RIIMILYHLYGA 255
+ +++ +L R S + + + + T ++ + ++F W P I +I+ L
Sbjct: 344 TVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTI 403
Query: 256 PIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFR 293
P V IA L N+ +N LY F+ + F+
Sbjct: 404 PETTFQTVSWHFCIA--LGYTNSCLNPVLYAFLDENFK 439
>gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]
Length = 400
Score = 65.1 bits (157), Expect = 9e-11
Identities = 63/278 (22%), Positives = 123/278 (44%), Gaps = 25/278 (8%)
Query: 33 YSLLLCLGLPANILTVIILSQLVARRQKSSYN-YLLALAAADILVLFFIVF--VDFLLED 89
YS++ +GL N L + ++ + + K++ N Y+ LA AD L + F V++L+
Sbjct: 77 YSIVCVVGLFGNFLVMYVIVRYT--KMKTATNIYIFNLALADALATSTLPFQSVNYLMGT 134
Query: 90 FILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCHPLKYHTVSYPARTRKVI 149
+ + KI+ +++ ++ TSI+ +++DRYIAVCHP+K P + +
Sbjct: 135 WPFGT----ILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIIN 190
Query: 150 VSVYITCFLTSIPYYWWPNI----WTEDYISTSVHHVLIWIHCFTV------YLVPCSIF 199
V +I +P + + D T H W + + +++P I
Sbjct: 191 VCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLII 250
Query: 200 FILNSIIVYKL---RRKSNFRLRGYSTGKTTAILFTITSIFATLWAP-RIIMILYHLYGA 255
+ +++ +L R S + + + + T ++ + ++F W P I +I+ L
Sbjct: 251 TVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTI 310
Query: 256 PIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFR 293
P V IA L N+ +N LY F+ + F+
Sbjct: 311 PETTFQTVSWHFCIA--LGYTNSCLNPVLYAFLDENFK 346
>gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]
Length = 420
Score = 65.1 bits (157), Expect = 9e-11
Identities = 63/278 (22%), Positives = 123/278 (44%), Gaps = 25/278 (8%)
Query: 33 YSLLLCLGLPANILTVIILSQLVARRQKSSYN-YLLALAAADILVLFFIVF--VDFLLED 89
YS++ +GL N L + ++ + + K++ N Y+ LA AD L + F V++L+
Sbjct: 77 YSIVCVVGLFGNFLVMYVIVRYT--KMKTATNIYIFNLALADALATSTLPFQSVNYLMGT 134
Query: 90 FILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCHPLKYHTVSYPARTRKVI 149
+ + KI+ +++ ++ TSI+ +++DRYIAVCHP+K P + +
Sbjct: 135 WPFGT----ILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIIN 190
Query: 150 VSVYITCFLTSIPYYWWPNI----WTEDYISTSVHHVLIWIHCFTV------YLVPCSIF 199
V +I +P + + D T H W + + +++P I
Sbjct: 191 VCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLII 250
Query: 200 FILNSIIVYKL---RRKSNFRLRGYSTGKTTAILFTITSIFATLWAP-RIIMILYHLYGA 255
+ +++ +L R S + + + + T ++ + ++F W P I +I+ L
Sbjct: 251 TVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTI 310
Query: 256 PIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFR 293
P V IA L N+ +N LY F+ + F+
Sbjct: 311 PETTFQTVSWHFCIA--LGYTNSCLNPVLYAFLDENFK 346
>gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]
Length = 397
Score = 65.1 bits (157), Expect = 9e-11
Identities = 63/278 (22%), Positives = 123/278 (44%), Gaps = 25/278 (8%)
Query: 33 YSLLLCLGLPANILTVIILSQLVARRQKSSYN-YLLALAAADILVLFFIVF--VDFLLED 89
YS++ +GL N L + ++ + + K++ N Y+ LA AD L + F V++L+
Sbjct: 77 YSIVCVVGLFGNFLVMYVIVRYT--KMKTATNIYIFNLALADALATSTLPFQSVNYLMGT 134
Query: 90 FILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCHPLKYHTVSYPARTRKVI 149
+ + KI+ +++ ++ TSI+ +++DRYIAVCHP+K P + +
Sbjct: 135 WPFGT----ILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIIN 190
Query: 150 VSVYITCFLTSIPYYWWPNI----WTEDYISTSVHHVLIWIHCFTV------YLVPCSIF 199
V +I +P + + D T H W + + +++P I
Sbjct: 191 VCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLII 250
Query: 200 FILNSIIVYKL---RRKSNFRLRGYSTGKTTAILFTITSIFATLWAP-RIIMILYHLYGA 255
+ +++ +L R S + + + + T ++ + ++F W P I +I+ L
Sbjct: 251 TVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTI 310
Query: 256 PIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFR 293
P V IA L N+ +N LY F+ + F+
Sbjct: 311 PETTFQTVSWHFCIA--LGYTNSCLNPVLYAFLDENFK 346
>gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens]
Length = 403
Score = 65.1 bits (157), Expect = 9e-11
Identities = 63/278 (22%), Positives = 123/278 (44%), Gaps = 25/278 (8%)
Query: 33 YSLLLCLGLPANILTVIILSQLVARRQKSSYN-YLLALAAADILVLFFIVF--VDFLLED 89
YS++ +GL N L + ++ + + K++ N Y+ LA AD L + F V++L+
Sbjct: 77 YSIVCVVGLFGNFLVMYVIVRYT--KMKTATNIYIFNLALADALATSTLPFQSVNYLMGT 134
Query: 90 FILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCHPLKYHTVSYPARTRKVI 149
+ + KI+ +++ ++ TSI+ +++DRYIAVCHP+K P + +
Sbjct: 135 WPFGT----ILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIIN 190
Query: 150 VSVYITCFLTSIPYYWWPNI----WTEDYISTSVHHVLIWIHCFTV------YLVPCSIF 199
V +I +P + + D T H W + + +++P I
Sbjct: 191 VCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLII 250
Query: 200 FILNSIIVYKL---RRKSNFRLRGYSTGKTTAILFTITSIFATLWAP-RIIMILYHLYGA 255
+ +++ +L R S + + + + T ++ + ++F W P I +I+ L
Sbjct: 251 TVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTI 310
Query: 256 PIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFR 293
P V IA L N+ +N LY F+ + F+
Sbjct: 311 PETTFQTVSWHFCIA--LGYTNSCLNPVLYAFLDENFK 346
>gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens]
Length = 406
Score = 65.1 bits (157), Expect = 9e-11
Identities = 63/278 (22%), Positives = 123/278 (44%), Gaps = 25/278 (8%)
Query: 33 YSLLLCLGLPANILTVIILSQLVARRQKSSYN-YLLALAAADILVLFFIVF--VDFLLED 89
YS++ +GL N L + ++ + + K++ N Y+ LA AD L + F V++L+
Sbjct: 77 YSIVCVVGLFGNFLVMYVIVRYT--KMKTATNIYIFNLALADALATSTLPFQSVNYLMGT 134
Query: 90 FILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCHPLKYHTVSYPARTRKVI 149
+ + KI+ +++ ++ TSI+ +++DRYIAVCHP+K P + +
Sbjct: 135 WPFGT----ILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIIN 190
Query: 150 VSVYITCFLTSIPYYWWPNI----WTEDYISTSVHHVLIWIHCFTV------YLVPCSIF 199
V +I +P + + D T H W + + +++P I
Sbjct: 191 VCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLII 250
Query: 200 FILNSIIVYKL---RRKSNFRLRGYSTGKTTAILFTITSIFATLWAP-RIIMILYHLYGA 255
+ +++ +L R S + + + + T ++ + ++F W P I +I+ L
Sbjct: 251 TVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTI 310
Query: 256 PIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFR 293
P V IA L N+ +N LY F+ + F+
Sbjct: 311 PETTFQTVSWHFCIA--LGYTNSCLNPVLYAFLDENFK 346
>gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens]
Length = 392
Score = 65.1 bits (157), Expect = 9e-11
Identities = 63/278 (22%), Positives = 123/278 (44%), Gaps = 25/278 (8%)
Query: 33 YSLLLCLGLPANILTVIILSQLVARRQKSSYN-YLLALAAADILVLFFIVF--VDFLLED 89
YS++ +GL N L + ++ + + K++ N Y+ LA AD L + F V++L+
Sbjct: 77 YSIVCVVGLFGNFLVMYVIVRYT--KMKTATNIYIFNLALADALATSTLPFQSVNYLMGT 134
Query: 90 FILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCHPLKYHTVSYPARTRKVI 149
+ + KI+ +++ ++ TSI+ +++DRYIAVCHP+K P + +
Sbjct: 135 WPFGT----ILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIIN 190
Query: 150 VSVYITCFLTSIPYYWWPNI----WTEDYISTSVHHVLIWIHCFTV------YLVPCSIF 199
V +I +P + + D T H W + + +++P I
Sbjct: 191 VCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLII 250
Query: 200 FILNSIIVYKL---RRKSNFRLRGYSTGKTTAILFTITSIFATLWAP-RIIMILYHLYGA 255
+ +++ +L R S + + + + T ++ + ++F W P I +I+ L
Sbjct: 251 TVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTI 310
Query: 256 PIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFR 293
P V IA L N+ +N LY F+ + F+
Sbjct: 311 PETTFQTVSWHFCIA--LGYTNSCLNPVLYAFLDENFK 346
>gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens]
Length = 389
Score = 65.1 bits (157), Expect = 9e-11
Identities = 63/278 (22%), Positives = 123/278 (44%), Gaps = 25/278 (8%)
Query: 33 YSLLLCLGLPANILTVIILSQLVARRQKSSYN-YLLALAAADILVLFFIVF--VDFLLED 89
YS++ +GL N L + ++ + + K++ N Y+ LA AD L + F V++L+
Sbjct: 77 YSIVCVVGLFGNFLVMYVIVRYT--KMKTATNIYIFNLALADALATSTLPFQSVNYLMGT 134
Query: 90 FILNMQMPQVPDKIIEVLEFSSIHTSIWITVPLTIDRYIAVCHPLKYHTVSYPARTRKVI 149
+ + KI+ +++ ++ TSI+ +++DRYIAVCHP+K P + +
Sbjct: 135 WPFGT----ILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIIN 190
Query: 150 VSVYITCFLTSIPYYWWPNI----WTEDYISTSVHHVLIWIHCFTV------YLVPCSIF 199
V +I +P + + D T H W + + +++P I
Sbjct: 191 VCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLII 250
Query: 200 FILNSIIVYKL---RRKSNFRLRGYSTGKTTAILFTITSIFATLWAP-RIIMILYHLYGA 255
+ +++ +L R S + + + + T ++ + ++F W P I +I+ L
Sbjct: 251 TVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTI 310
Query: 256 PIQNRWLVHIMSDIANMLALLNTAINFFLYCFISKRFR 293
P V IA L N+ +N LY F+ + F+
Sbjct: 311 PETTFQTVSWHFCIA--LGYTNSCLNPVLYAFLDENFK 346
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.330 0.140 0.455
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,445,316
Number of Sequences: 37866
Number of extensions: 488262
Number of successful extensions: 2309
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 351
Number of HSP's successfully gapped in prelim test: 258
Number of HSP's that attempted gapping in prelim test: 1681
Number of HSP's gapped (non-prelim): 698
length of query: 353
length of database: 18,247,518
effective HSP length: 103
effective length of query: 250
effective length of database: 14,347,320
effective search space: 3586830000
effective search space used: 3586830000
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.