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Search of human proteins with 50592994
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50592994 thioredoxin [Homo sapiens]
(105 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50592994 thioredoxin [Homo sapiens] 216 3e-57
gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo sap... 137 1e-33
gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo sap... 137 1e-33
gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo sapi... 137 1e-33
gi|51510891 thioredoxin domain containing 8 [Homo sapiens] 95 1e-20
gi|4759274 thioredoxin-like 1 [Homo sapiens] 86 6e-18
gi|21361403 thioredoxin 2 precursor [Homo sapiens] 69 1e-12
gi|95113651 glutaredoxin 3 [Homo sapiens] 59 1e-09
gi|42794771 thioredoxin domain containing 5 isoform 1 precursor ... 51 2e-07
gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo sap... 51 2e-07
gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo s... 49 6e-07
gi|148839372 thioredoxin domain containing 3 [Homo sapiens] 49 8e-07
gi|4758304 protein disulfide isomerase A4 [Homo sapiens] 48 1e-06
gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens] 47 2e-06
gi|5803121 protein disulfide isomerase A5 [Homo sapiens] 44 4e-05
gi|52487191 thioredoxin domain containing 4 (endoplasmic reticul... 42 1e-04
gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo s... 42 1e-04
gi|94966757 protein disulfide isomerase A2 [Homo sapiens] 40 4e-04
gi|5031973 protein disulfide isomerase A6 [Homo sapiens] 40 4e-04
gi|30023828 thioredoxin domain containing 6 [Homo sapiens] 39 7e-04
gi|38505222 thioredoxin domain containing 10 [Homo sapiens] 39 7e-04
gi|28372543 protein disulfide isomerase-like, testis expressed [... 37 0.003
gi|221136993 thioredoxin domain containing 14 isoform 2 [Homo sa... 36 0.006
gi|7705726 thioredoxin domain containing 14 isoform 1 [Homo sapi... 36 0.006
gi|5729802 thioredoxin-like 4A [Homo sapiens] 33 0.048
gi|145580631 quiescin Q6 sulfhydryl oxidase 2 [Homo sapiens] 32 0.11
gi|151101292 thioredoxin domain containing 1 [Homo sapiens] 32 0.11
gi|51944950 phosducin-like 2 [Homo sapiens] 32 0.11
gi|94421469 disulfide isomerase [Homo sapiens] 32 0.14
gi|51873067 quiescin Q6 sulfhydryl oxidase 1 isoform b [Homo sap... 31 0.18
>gi|50592994 thioredoxin [Homo sapiens]
Length = 105
Score = 216 bits (550), Expect = 3e-57
Identities = 105/105 (100%), Positives = 105/105 (100%)
Query: 1 MVKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVD 60
MVKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVD
Sbjct: 1 MVKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVD 60
Query: 61 DCQDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKLEATINELV 105
DCQDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKLEATINELV
Sbjct: 61 DCQDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKLEATINELV 105
>gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo
sapiens]
Length = 486
Score = 137 bits (346), Expect = 1e-33
Identities = 63/103 (61%), Positives = 80/103 (77%)
Query: 2 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDD 61
VK I SK F+ +L AG++LV VDFSATWCGPC+ I+PFFH+LS K+ +V+FLEVD D+
Sbjct: 383 VKVILSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFHALSVKHEDVVFLEVDADN 442
Query: 62 CQDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKLEATINEL 104
C++V EC + C+PTFQF+KK +KV E GA KEKLEA I EL
Sbjct: 443 CEEVVRECAIMCVPTFQFYKKEEKVDELCGALKEKLEAVIAEL 485
>gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo
sapiens]
Length = 553
Score = 137 bits (346), Expect = 1e-33
Identities = 63/103 (61%), Positives = 80/103 (77%)
Query: 2 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDD 61
VK I SK F+ +L AG++LV VDFSATWCGPC+ I+PFFH+LS K+ +V+FLEVD D+
Sbjct: 450 VKVILSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFHALSVKHEDVVFLEVDADN 509
Query: 62 CQDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKLEATINEL 104
C++V EC + C+PTFQF+KK +KV E GA KEKLEA I EL
Sbjct: 510 CEEVVRECAIMCVPTFQFYKKEEKVDELCGALKEKLEAVIAEL 552
>gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo
sapiens]
Length = 486
Score = 137 bits (346), Expect = 1e-33
Identities = 63/103 (61%), Positives = 80/103 (77%)
Query: 2 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDD 61
VK I SK F+ +L AG++LV VDFSATWCGPC+ I+PFFH+LS K+ +V+FLEVD D+
Sbjct: 383 VKVILSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFHALSVKHEDVVFLEVDADN 442
Query: 62 CQDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKLEATINEL 104
C++V EC + C+PTFQF+KK +KV E GA KEKLEA I EL
Sbjct: 443 CEEVVRECAIMCVPTFQFYKKEEKVDELCGALKEKLEAVIAEL 485
>gi|51510891 thioredoxin domain containing 8 [Homo sapiens]
Length = 115
Score = 94.7 bits (234), Expect = 1e-20
Identities = 46/90 (51%), Positives = 59/90 (65%)
Query: 1 MVKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVD 60
MV+ I+ F+ L AAG KL VV FS+ CGPCK + P FH++S KY NV F VDV+
Sbjct: 1 MVQIIKDTNEFKTFLTAAGHKLAVVQFSSKRCGPCKRMFPVFHAMSVKYQNVFFANVDVN 60
Query: 61 DCQDVASECEVKCMPTFQFFKKGQKVGEFS 90
+ ++A C +K +PTFQ FKK QKV FS
Sbjct: 61 NSPELAETCHIKTIPTFQMFKKSQKVTLFS 90
>gi|4759274 thioredoxin-like 1 [Homo sapiens]
Length = 289
Score = 85.9 bits (211), Expect = 6e-18
Identities = 42/102 (41%), Positives = 56/102 (54%)
Query: 2 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDD 61
VK + S FQ L AG +L VV F+ CGPC I P F S+S KY +FLEVDV
Sbjct: 4 VKPVGSDPDFQPELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVDVHQ 63
Query: 62 CQDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKLEATINE 103
CQ A+ + PTF FF+ ++ ++ GA+ LE I +
Sbjct: 64 CQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKIKQ 105
>gi|21361403 thioredoxin 2 precursor [Homo sapiens]
Length = 166
Score = 68.6 bits (166), Expect = 1e-12
Identities = 34/85 (40%), Positives = 54/85 (63%), Gaps = 2/85 (2%)
Query: 23 VVVDFSATWCGPCKMIKPFFHSL-SEKYSNVIFLEVDVDDCQDVASECEVKCMPTFQFFK 81
VVVDF A WCGPCK++ P + ++++ V+ +VD+DD D+A E EV +PT K
Sbjct: 81 VVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAIEYEVSAVPTVLAMK 140
Query: 82 KGQKVGEFSG-ANKEKLEATINELV 105
G V +F G ++++LEA + +L+
Sbjct: 141 NGDVVDKFVGIKDEDQLEAFLKKLI 165
>gi|95113651 glutaredoxin 3 [Homo sapiens]
Length = 335
Score = 58.5 bits (140), Expect = 1e-09
Identities = 28/96 (29%), Positives = 50/96 (52%)
Query: 2 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDD 61
V+++ S F+E L L+VV F A W C + L+++ V F++++ +
Sbjct: 13 VEEVGSAGQFEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQVSFVKLEAEG 72
Query: 62 CQDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKL 97
+V+ + E+ +PTF FFK QK+ GA+ +L
Sbjct: 73 VPEVSEKYEISSVPTFLFFKNSQKIDRLDGAHAPEL 108
>gi|42794771 thioredoxin domain containing 5 isoform 1 precursor
[Homo sapiens]
Length = 432
Score = 51.2 bits (121), Expect = 2e-07
Identities = 27/80 (33%), Positives = 41/80 (51%), Gaps = 4/80 (5%)
Query: 16 DAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEK----YSNVIFLEVDVDDCQDVASECEV 71
D + + + F A WCG CK + P + LS+K + V EVD +++ S+ V
Sbjct: 334 DTIAEGITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSV 393
Query: 72 KCMPTFQFFKKGQKVGEFSG 91
+ PT F+ G+KV E SG
Sbjct: 394 RGYPTLLLFRGGKKVSEHSG 413
Score = 47.8 bits (112), Expect = 2e-06
Identities = 25/72 (34%), Positives = 39/72 (54%), Gaps = 5/72 (6%)
Query: 25 VDFSATWCGPCKMIKPFFHSLSEKYSN-----VIFLEVDVDDCQDVASECEVKCMPTFQF 79
V F A WCG C+ ++P ++ L +KY++ V +VD DV S V+ PT +
Sbjct: 82 VMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLKL 141
Query: 80 FKKGQKVGEFSG 91
FK GQ+ ++ G
Sbjct: 142 FKPGQEAVKYQG 153
Score = 43.1 bits (100), Expect = 5e-05
Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 7/86 (8%)
Query: 17 AAGDKLVVVDFSATWCGPCKMIKPFFHSLS---EKYSNVIFLEVDVDDCQDVASECEVKC 73
A GD + F A WCG CK + P + L+ E V +VD ++ S +V+
Sbjct: 204 AQGDHFI--KFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCSGNQVRG 261
Query: 74 MPTFQFFKKGQKVGEFSGANKEKLEA 99
PT +F+ G+KV ++ G K LE+
Sbjct: 262 YPTLLWFRDGKKVDQYKG--KRDLES 285
>gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo
sapiens]
Length = 324
Score = 51.2 bits (121), Expect = 2e-07
Identities = 27/80 (33%), Positives = 41/80 (51%), Gaps = 4/80 (5%)
Query: 16 DAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEK----YSNVIFLEVDVDDCQDVASECEV 71
D + + + F A WCG CK + P + LS+K + V EVD +++ S+ V
Sbjct: 226 DTIAEGITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSV 285
Query: 72 KCMPTFQFFKKGQKVGEFSG 91
+ PT F+ G+KV E SG
Sbjct: 286 RGYPTLLLFRGGKKVSEHSG 305
Score = 43.1 bits (100), Expect = 5e-05
Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 7/86 (8%)
Query: 17 AAGDKLVVVDFSATWCGPCKMIKPFFHSLS---EKYSNVIFLEVDVDDCQDVASECEVKC 73
A GD + F A WCG CK + P + L+ E V +VD ++ S +V+
Sbjct: 96 AQGDHFI--KFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCSGNQVRG 153
Query: 74 MPTFQFFKKGQKVGEFSGANKEKLEA 99
PT +F+ G+KV ++ G K LE+
Sbjct: 154 YPTLLWFRDGKKVDQYKG--KRDLES 177
Score = 26.9 bits (58), Expect = 3.4
Identities = 14/42 (33%), Positives = 21/42 (50%)
Query: 50 SNVIFLEVDVDDCQDVASECEVKCMPTFQFFKKGQKVGEFSG 91
+ V +VD DV S V+ PT + FK GQ+ ++ G
Sbjct: 4 AKVYVAKVDCTAHSDVCSAQGVRGYPTLKLFKPGQEAVKYQG 45
>gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo
sapiens]
Length = 508
Score = 49.3 bits (116), Expect = 6e-07
Identities = 28/80 (35%), Positives = 43/80 (53%), Gaps = 6/80 (7%)
Query: 8 KTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKY----SNVIFLEVDVDDCQ 63
K+ F EAL A K ++V+F A WCG CK + P + + K S + +VD +
Sbjct: 31 KSNFAEAL--AAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEES 88
Query: 64 DVASECEVKCMPTFQFFKKG 83
D+A + V+ PT +FF+ G
Sbjct: 89 DLAQQYGVRGYPTIKFFRNG 108
Score = 41.2 bits (95), Expect = 2e-04
Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 11/66 (16%)
Query: 21 KLVVVDFSATWCGPCKMIKPFFHSLSEKY---SNVIFLEVDVDDCQDVASECE---VKCM 74
K V V+F A WCG CK + P + L E Y N++ ++D A+E E V
Sbjct: 386 KNVFVEFYAPWCGHCKQLAPIWDKLGETYKDHENIVIAKMD-----STANEVEAVKVHSF 440
Query: 75 PTFQFF 80
PT +FF
Sbjct: 441 PTLKFF 446
>gi|148839372 thioredoxin domain containing 3 [Homo sapiens]
Length = 588
Score = 48.9 bits (115), Expect = 8e-07
Identities = 27/103 (26%), Positives = 47/103 (45%), Gaps = 4/103 (3%)
Query: 5 IESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDDCQD 64
I +++ + E L G L V+D WCGPC+ ++P F L + + L V + +
Sbjct: 14 INNQSLWDEMLQNKG--LTVIDVYQAWCGPCRAMQPLFRKLKNELNEDEILHFAVAEADN 71
Query: 65 VAS--ECEVKCMPTFQFFKKGQKVGEFSGANKEKLEATINELV 105
+ + KC P F F G+ + + GAN + + L+
Sbjct: 72 IVTLQPFRDKCEPVFLFSVNGKIIEKIQGANAPLVNKKVINLI 114
>gi|4758304 protein disulfide isomerase A4 [Homo sapiens]
Length = 645
Score = 48.1 bits (113), Expect = 1e-06
Identities = 28/99 (28%), Positives = 50/99 (50%), Gaps = 7/99 (7%)
Query: 2 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKY---SNVIFLEVD 58
VK + KT +D D V+++F A WCG CK ++P ++SL++KY ++ ++D
Sbjct: 527 VKVVVGKTFDSIVMDPKKD--VLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMD 584
Query: 59 VDDCQDVASECEVKCMPTFQFFKKGQKVG--EFSGANKE 95
+ +V+ PT F G K +F G +++
Sbjct: 585 ATANDVPSDRYKVEGFPTIYFAPSGDKKNPVKFEGGDRD 623
Score = 47.4 bits (111), Expect = 2e-06
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 4/86 (4%)
Query: 23 VVVDFSATWCGPCKMIKPFFHS----LSEKYSNVIFLEVDVDDCQDVASECEVKCMPTFQ 78
V+++F A WCG CK P + L +K + ++D +AS +V PT +
Sbjct: 82 VLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPTIK 141
Query: 79 FFKKGQKVGEFSGANKEKLEATINEL 104
KKGQ V +E++ A + E+
Sbjct: 142 ILKKGQAVDYEGSRTQEEIVAKVREV 167
Score = 45.4 bits (106), Expect = 9e-06
Identities = 26/87 (29%), Positives = 45/87 (51%), Gaps = 6/87 (6%)
Query: 2 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFH----SLSEKYSNVIFLEV 57
V + +K F E ++ A +++V+F A WCG CK + P + LS++ + +V
Sbjct: 178 VTLVLTKENFDEVVNDAD--IILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKV 235
Query: 58 DVDDCQDVASECEVKCMPTFQFFKKGQ 84
D D+A +V PT + F+KG+
Sbjct: 236 DATAETDLAKRFDVSGYPTLKIFRKGR 262
>gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens]
Length = 505
Score = 47.4 bits (111), Expect = 2e-06
Identities = 25/70 (35%), Positives = 39/70 (55%), Gaps = 4/70 (5%)
Query: 20 DKLVVVDFSATWCGPCKMIKPFFHSLSEKYS---NVIFLEVDVDDCQDVASECEVKCMPT 76
+K V+++F A WCG CK ++P + L EK S N++ ++D DV S EV+ PT
Sbjct: 394 NKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDA-TANDVPSPYEVRGFPT 452
Query: 77 FQFFKKGQKV 86
F +K+
Sbjct: 453 IYFSPANKKL 462
Score = 45.4 bits (106), Expect = 9e-06
Identities = 21/77 (27%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Query: 16 DAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFL-EVDVDDCQDVASECEVKCM 74
D L++V+F A WCG CK + P + + + + ++ L +VD + ++ V
Sbjct: 41 DTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGY 100
Query: 75 PTFQFFKKGQKVGEFSG 91
PT + F+ G++ G + G
Sbjct: 101 PTLKIFRDGEEAGAYDG 117
>gi|5803121 protein disulfide isomerase A5 [Homo sapiens]
Length = 519
Score = 43.5 bits (101), Expect = 4e-05
Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 5/68 (7%)
Query: 23 VVVDFSATWCGPCKMIKPFFHSLSEKY-----SNVIFLEVDVDDCQDVASECEVKCMPTF 77
V+V F A WCG CK +KP F +E S+ + VD + +A + PT
Sbjct: 296 VLVMFHAPWCGHCKKMKPEFEKAAEALHGEADSSGVLAAVDATVNKALAERFHISEFPTL 355
Query: 78 QFFKKGQK 85
++FK G+K
Sbjct: 356 KYFKNGEK 363
Score = 37.4 bits (85), Expect = 0.003
Identities = 21/86 (24%), Positives = 44/86 (51%), Gaps = 4/86 (4%)
Query: 2 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEK---YSNVIFLEVD 58
V ++S+ F+ L +K +++ F A WC CK + P F + + ++ + + V
Sbjct: 153 VVHLDSEKDFRRLLKKE-EKPLLIMFYAPWCSMCKRMMPHFQKAATQLRGHAVLAGMNVY 211
Query: 59 VDDCQDVASECEVKCMPTFQFFKKGQ 84
+ +++ E V+ PT +F+KG+
Sbjct: 212 SSEFENIKEEYSVRGFPTICYFEKGR 237
Score = 37.4 bits (85), Expect = 0.003
Identities = 24/90 (26%), Positives = 40/90 (44%), Gaps = 7/90 (7%)
Query: 11 FQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDDC-----QDV 65
F+E L LV+ F A WC CK + P F + ++ + + + DC QD+
Sbjct: 407 FRETLKKKKHTLVM--FYAPWCPHCKKVIPHFTATADAFKDDRKIACAAVDCVKDKNQDL 464
Query: 66 ASECEVKCMPTFQFFKKGQKVGEFSGANKE 95
+ VK PTF ++ G+ ++ E
Sbjct: 465 CQQEAVKGYPTFHYYHYGKFAEKYDSDRTE 494
>gi|52487191 thioredoxin domain containing 4 (endoplasmic reticulum)
[Homo sapiens]
Length = 406
Score = 42.0 bits (97), Expect = 1e-04
Identities = 25/83 (30%), Positives = 39/83 (46%), Gaps = 8/83 (9%)
Query: 22 LVVVDFSATWCGPCKMIKPFFHSLS----EKYSN---VIFLEVDVDDCQDVASECEVKCM 74
+ +V+F A WC +M+ P F S E++ N V+F VD D D+A +
Sbjct: 48 VALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKY 107
Query: 75 PTFQFFKKGQKV-GEFSGANKEK 96
PT + F+ G + E+ G K
Sbjct: 108 PTLKLFRNGMMMKREYRGQRSVK 130
>gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo
sapiens]
Length = 793
Score = 41.6 bits (96), Expect = 1e-04
Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 5/60 (8%)
Query: 24 VVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDDCQDVASECE---VKCMPTFQFF 80
V+DF A WCGPC+ P F L+ + + DCQ A C+ ++ PT +F+
Sbjct: 692 VIDFYAPWCGPCQNFAPEFELLARMIKGKV--KAGKVDCQAYAQTCQKAGIRAYPTVKFY 749
Score = 36.2 bits (82), Expect = 0.006
Identities = 22/79 (27%), Positives = 38/79 (48%), Gaps = 9/79 (11%)
Query: 24 VVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDDCQDVASEC---EVKCMPTFQFF 80
+VDF + WC PC+++ P + ++ + +I V DCQ S C V+ P +FF
Sbjct: 580 MVDFYSPWCHPCQVLMPEWKRMARTLTGLI--NVGSIDCQQYHSFCAQENVQRYPEIRFF 637
Query: 81 ----KKGQKVGEFSGANKE 95
K ++G N++
Sbjct: 638 PPKSNKAYHYHSYNGWNRD 656
Score = 31.2 bits (69), Expect = 0.18
Identities = 18/69 (26%), Positives = 31/69 (44%), Gaps = 2/69 (2%)
Query: 24 VVDFSATWCGPCKMIKPFFHSLSE-KYSNVIFLEVDVDDCQDVASECEVKCMPTFQFFKK 82
+VDF A WC PC+ + P S Y + F +D + + + ++ PT F +
Sbjct: 472 LVDFFAPWCPPCRALLPELRRASNLLYGQLKFGTLDCTVHEGLCNMYNIQAYPTTVVFNQ 531
Query: 83 GQKVGEFSG 91
+ E+ G
Sbjct: 532 -SNIHEYEG 539
>gi|94966757 protein disulfide isomerase A2 [Homo sapiens]
Length = 525
Score = 40.0 bits (92), Expect = 4e-04
Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 15/96 (15%)
Query: 2 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKY---SNVIFLEVD 58
VK + K Q A D K V V F A WC CK + P + +L+EKY ++I E+D
Sbjct: 390 VKTLVGKNFEQVAFDET--KNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAELD 447
Query: 59 VDDCQDVASECE---VKCMPTFQFFK--KGQKVGEF 89
A+E + V PT ++F G+KV E+
Sbjct: 448 A-----TANELDAFAVHGFPTLKYFPAGPGRKVIEY 478
Score = 37.4 bits (85), Expect = 0.003
Identities = 20/67 (29%), Positives = 35/67 (52%), Gaps = 4/67 (5%)
Query: 23 VVVDFSATWCGPCKMIKPFFHS----LSEKYSNVIFLEVDVDDCQDVASECEVKCMPTFQ 78
++V+F A WCG C+ + P + L+ + V +VD +++A E V PT +
Sbjct: 62 LLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLK 121
Query: 79 FFKKGQK 85
FF+ G +
Sbjct: 122 FFRNGNR 128
>gi|5031973 protein disulfide isomerase A6 [Homo sapiens]
Length = 440
Score = 40.0 bits (92), Expect = 4e-04
Identities = 28/97 (28%), Positives = 45/97 (46%), Gaps = 12/97 (12%)
Query: 7 SKTAFQEALDAAGDKLVV-------VDFSATWCGPCKMIKPFFHSLSEKY-----SNVIF 54
SK E D + DK V+ V+F A WCG CK ++P + + + + V
Sbjct: 158 SKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKL 217
Query: 55 LEVDVDDCQDVASECEVKCMPTFQFFKKGQKVGEFSG 91
VD Q +AS ++ PT + F+KG+ ++ G
Sbjct: 218 AAVDATVNQVLASRYGIRGFPTIKIFQKGESPVDYDG 254
Score = 36.2 bits (82), Expect = 0.006
Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 11/80 (13%)
Query: 20 DKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFL-EVDVDDCQDVASECEVKCMPTFQ 78
D L +V+F A WCG C+ + P + + +V+ + VD D + + V+ PT +
Sbjct: 43 DSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIK 102
Query: 79 FFKKGQKVGEFSGANKEKLE 98
F G+NK + E
Sbjct: 103 IF----------GSNKNRPE 112
>gi|30023828 thioredoxin domain containing 6 [Homo sapiens]
Length = 263
Score = 39.3 bits (90), Expect = 7e-04
Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 1/60 (1%)
Query: 22 LVVVDFSATWCGPCKMIKPFFHSLS-EKYSNVIFLEVDVDDCQDVASECEVKCMPTFQFF 80
L VVD WCGPCK + F + E +++ + D DV + KC PTF F+
Sbjct: 7 LTVVDVYQGWCGPCKPVVSLFQKMRIEVGLDLLHFALAEADRLDVLEKYRGKCEPTFLFY 66
>gi|38505222 thioredoxin domain containing 10 [Homo sapiens]
Length = 454
Score = 39.3 bits (90), Expect = 7e-04
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 9/80 (11%)
Query: 11 FQEALDAA-----GDKLVVVDFSATWCGPCKMIKPFFHSLSEKY----SNVIFLEVDVDD 61
F E LD + D + +VDF A WCG CK ++P ++ + + S V ++D
Sbjct: 27 FVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATS 86
Query: 62 CQDVASECEVKCMPTFQFFK 81
+ASE V+ PT + K
Sbjct: 87 YSSIASEFGVRGYPTIKLLK 106
>gi|28372543 protein disulfide isomerase-like, testis expressed
[Homo sapiens]
Length = 584
Score = 37.0 bits (84), Expect = 0.003
Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 10/84 (11%)
Query: 1 MVKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSN---VIFLEV 57
+VKQ+ K D D V V F A W CKM+ P L KY N +I ++
Sbjct: 388 LVKQLVGKNFNVVVFDKEKD--VFVMFYAPWSKKCKMLFPLLEELGRKYQNHSTIIIAKI 445
Query: 58 DVDDCQDVASECEVKCMPTFQFFK 81
DV A++ ++ + + FF+
Sbjct: 446 DV-----TANDIQLMYLDRYPFFR 464
>gi|221136993 thioredoxin domain containing 14 isoform 2 [Homo
sapiens]
Length = 258
Score = 36.2 bits (82), Expect = 0.006
Identities = 29/94 (30%), Positives = 45/94 (47%), Gaps = 13/94 (13%)
Query: 2 VKQIESKTAFQEALDAAGDKLV--VVDFSATWCGPCKMIKPFFHSLSEKY--SNVIFLEV 57
+K KT +E DK V +V+F A W C+ P + LS KY + + F +V
Sbjct: 100 IKYFNDKTIDEEL---ERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKYNCTGLNFGKV 156
Query: 58 DVDDCQDVASECEV------KCMPTFQFFKKGQK 85
DV DV++ +V K +PT F+ G++
Sbjct: 157 DVGRYTDVSTRYKVSTSPLTKQLPTLILFQGGKE 190
>gi|7705726 thioredoxin domain containing 14 isoform 1 [Homo
sapiens]
Length = 296
Score = 36.2 bits (82), Expect = 0.006
Identities = 29/94 (30%), Positives = 45/94 (47%), Gaps = 13/94 (13%)
Query: 2 VKQIESKTAFQEALDAAGDKLV--VVDFSATWCGPCKMIKPFFHSLSEKY--SNVIFLEV 57
+K KT +E DK V +V+F A W C+ P + LS KY + + F +V
Sbjct: 138 IKYFNDKTIDEEL---ERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKYNCTGLNFGKV 194
Query: 58 DVDDCQDVASECEV------KCMPTFQFFKKGQK 85
DV DV++ +V K +PT F+ G++
Sbjct: 195 DVGRYTDVSTRYKVSTSPLTKQLPTLILFQGGKE 228
>gi|5729802 thioredoxin-like 4A [Homo sapiens]
Length = 142
Score = 33.1 bits (74), Expect = 0.048
Identities = 22/88 (25%), Positives = 42/88 (47%), Gaps = 3/88 (3%)
Query: 1 MVKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSN--VIFLEVD 58
M+ + + +A+ + D++VV+ F W C + +S++EK N VI+L VD
Sbjct: 4 MLPHLHNGWQVDQAILSEEDRVVVIRFGHDWDPTCMKMDEVLYSIAEKVKNFAVIYL-VD 62
Query: 59 VDDCQDVASECEVKCMPTFQFFKKGQKV 86
+ + D E+ T FF + + +
Sbjct: 63 ITEVPDFNKMYELYDPCTVMFFFRNKHI 90
>gi|145580631 quiescin Q6 sulfhydryl oxidase 2 [Homo sapiens]
Length = 698
Score = 32.0 bits (71), Expect = 0.11
Identities = 24/82 (29%), Positives = 39/82 (47%), Gaps = 10/82 (12%)
Query: 24 VVDFSATWCGPCKMIKPFFHSLSEKYSN-VIFLEVDVDDC-----QDVASECEVKCMPTF 77
+V F ++WCG C P + +L+ + + V DC Q V + ++ PTF
Sbjct: 83 LVQFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTF 142
Query: 78 QFFKKGQK---VGE-FSGANKE 95
++FK K GE F G ++E
Sbjct: 143 RYFKAFTKEFTTGENFKGPDRE 164
>gi|151101292 thioredoxin domain containing 1 [Homo sapiens]
Length = 280
Score = 32.0 bits (71), Expect = 0.11
Identities = 16/63 (25%), Positives = 32/63 (50%), Gaps = 2/63 (3%)
Query: 24 VVDFSATWCGPCKMIKPFFHSLSE--KYSNVIFLEVDVDDCQDVASECEVKCMPTFQFFK 81
+++F A WC C+ ++P + S +E + V +VDV + ++ + +PT K
Sbjct: 48 MIEFYAPWCPACQNLQPEWESFAEWGEDLEVNIAKVDVTEQPGLSGRFIITALPTIYHCK 107
Query: 82 KGQ 84
G+
Sbjct: 108 DGE 110
>gi|51944950 phosducin-like 2 [Homo sapiens]
Length = 241
Score = 32.0 bits (71), Expect = 0.11
Identities = 19/90 (21%), Positives = 36/90 (40%), Gaps = 3/90 (3%)
Query: 2 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDD 61
+++I E +A D V++ + C ++ L+ K+ F++ V+
Sbjct: 92 LREISGNQYVNEVTNAEEDVWVIIHLYRSSIPMCLLVNQHLSLLARKFPETKFVKAIVNS 151
Query: 62 CQDVASECEVKCMPTFQFFKKGQKVGEFSG 91
C C+PT +K GQ +F G
Sbjct: 152 C---IQHYHDNCLPTIFVYKNGQIEAKFIG 178
>gi|94421469 disulfide isomerase [Homo sapiens]
Length = 360
Score = 31.6 bits (70), Expect = 0.14
Identities = 17/93 (18%), Positives = 37/93 (39%)
Query: 2 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDD 61
+K + + L+ G +V F WC + P F+SL + + FL +D
Sbjct: 190 LKILNMSQDLMDFLNPNGSDCTLVLFYTPWCRFSASLAPHFNSLPRAFPALHFLALDASQ 249
Query: 62 CQDVASECEVKCMPTFQFFKKGQKVGEFSGANK 94
+++ +P F+ + + F+ ++
Sbjct: 250 HSSLSTRFGTVAVPNILLFQGAKPMARFNHTDR 282
>gi|51873067 quiescin Q6 sulfhydryl oxidase 1 isoform b [Homo
sapiens]
Length = 604
Score = 31.2 bits (69), Expect = 0.18
Identities = 24/76 (31%), Positives = 36/76 (47%), Gaps = 12/76 (15%)
Query: 25 VDFSATWCGPCKMIKPFFHSLSE---KYSNVIFLEVDVDDCQD-----VASECEVKCMPT 76
V+F A+WCG C P + +L+E + ++L DC + V + + PT
Sbjct: 63 VEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLA--ALDCAEETNSAVCRDFNIPGFPT 120
Query: 77 FQFFKKGQKVGEFSGA 92
+FFK K G SGA
Sbjct: 121 VRFFKAFTKNG--SGA 134
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,479,241
Number of Sequences: 37866
Number of extensions: 123265
Number of successful extensions: 383
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 316
Number of HSP's gapped (non-prelim): 53
length of query: 105
length of database: 18,247,518
effective HSP length: 76
effective length of query: 29
effective length of database: 15,369,702
effective search space: 445721358
effective search space used: 445721358
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.