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Search of human proteins with 50513245
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
(956 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 1936 0.0
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 84 8e-16
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 82 2e-15
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 80 1e-14
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 79 3e-14
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 78 5e-14
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 77 6e-14
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 77 6e-14
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 77 6e-14
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 77 6e-14
gi|148746195 trichohyalin [Homo sapiens] 77 8e-14
gi|4505101 microtubule-associated protein 7 [Homo sapiens] 77 1e-13
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 73 1e-12
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 72 2e-12
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 72 2e-12
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 72 2e-12
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 72 3e-12
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 72 3e-12
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 72 3e-12
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 70 7e-12
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 70 7e-12
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 69 2e-11
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 69 2e-11
gi|56549694 enabled homolog isoform a [Homo sapiens] 69 2e-11
gi|39930375 enabled homolog isoform b [Homo sapiens] 69 2e-11
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 69 2e-11
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 68 4e-11
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 68 5e-11
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 68 5e-11
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 68 5e-11
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 1936 bits (5015), Expect = 0.0
Identities = 956/956 (100%), Positives = 956/956 (100%)
Query: 1 MLEELECGAPGARGAATAMDCKDRPAFPVKKLIQARLPFKRLNLVPKGKADDMSDDQGTS 60
MLEELECGAPGARGAATAMDCKDRPAFPVKKLIQARLPFKRLNLVPKGKADDMSDDQGTS
Sbjct: 1 MLEELECGAPGARGAATAMDCKDRPAFPVKKLIQARLPFKRLNLVPKGKADDMSDDQGTS 60
Query: 61 VQSKSPDLEASLDTLENNCHVGSDIDFRPKLVNGKGPLDNFLRNRIETSIGQSTVIIDLT 120
VQSKSPDLEASLDTLENNCHVGSDIDFRPKLVNGKGPLDNFLRNRIETSIGQSTVIIDLT
Sbjct: 61 VQSKSPDLEASLDTLENNCHVGSDIDFRPKLVNGKGPLDNFLRNRIETSIGQSTVIIDLT 120
Query: 121 EDSNEQPDSLVDHNKLNSEASPSREAINGQREDTGDQQGLLKAIQNDKLAFPGETLSDIP 180
EDSNEQPDSLVDHNKLNSEASPSREAINGQREDTGDQQGLLKAIQNDKLAFPGETLSDIP
Sbjct: 121 EDSNEQPDSLVDHNKLNSEASPSREAINGQREDTGDQQGLLKAIQNDKLAFPGETLSDIP 180
Query: 181 CKTEEEGVGCGGAGRRGDSQECSPRSCPELTSGPRMCPRKEQDSWSEAGGILFKGKVPMV 240
CKTEEEGVGCGGAGRRGDSQECSPRSCPELTSGPRMCPRKEQDSWSEAGGILFKGKVPMV
Sbjct: 181 CKTEEEGVGCGGAGRRGDSQECSPRSCPELTSGPRMCPRKEQDSWSEAGGILFKGKVPMV 240
Query: 241 VLQDILAVRPPQIKSLPATPQGKNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPP 300
VLQDILAVRPPQIKSLPATPQGKNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPP
Sbjct: 241 VLQDILAVRPPQIKSLPATPQGKNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPP 300
Query: 301 APPKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKL 360
APPKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKL
Sbjct: 301 APPKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKL 360
Query: 361 KEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLE 420
KEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLE
Sbjct: 361 KEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLE 420
Query: 421 EKRKKEEEKRLREEEKRIKAEKAEITRFFQKPKTPQAPKTLAGSCGKFAPFEIKEHMVLA 480
EKRKKEEEKRLREEEKRIKAEKAEITRFFQKPKTPQAPKTLAGSCGKFAPFEIKEHMVLA
Sbjct: 421 EKRKKEEEKRLREEEKRIKAEKAEITRFFQKPKTPQAPKTLAGSCGKFAPFEIKEHMVLA 480
Query: 481 PRRRTAFHPDLCSQLDQLLQQQSGEFSFLKDLKGRQPLRSGPTHVSTRNADIFNSDVVIV 540
PRRRTAFHPDLCSQLDQLLQQQSGEFSFLKDLKGRQPLRSGPTHVSTRNADIFNSDVVIV
Sbjct: 481 PRRRTAFHPDLCSQLDQLLQQQSGEFSFLKDLKGRQPLRSGPTHVSTRNADIFNSDVVIV 540
Query: 541 ERGKGDGVPERRKFGRMKLLQFCENHRPAYWGTWNKKTALIRARDPWAQDTKLLDYEVDS 600
ERGKGDGVPERRKFGRMKLLQFCENHRPAYWGTWNKKTALIRARDPWAQDTKLLDYEVDS
Sbjct: 541 ERGKGDGVPERRKFGRMKLLQFCENHRPAYWGTWNKKTALIRARDPWAQDTKLLDYEVDS 600
Query: 601 DEEWEEEEPGESLSHSEGDDDDDMGEDEDEDDGFFVPHGYLSEDEGVTEECADPENHKVR 660
DEEWEEEEPGESLSHSEGDDDDDMGEDEDEDDGFFVPHGYLSEDEGVTEECADPENHKVR
Sbjct: 601 DEEWEEEEPGESLSHSEGDDDDDMGEDEDEDDGFFVPHGYLSEDEGVTEECADPENHKVR 660
Query: 661 QKLKAKEWDEFLAKGKRFRVLQPVKIGCVWAADRDCAGDDLKVLQQFAACFLETLPAQEE 720
QKLKAKEWDEFLAKGKRFRVLQPVKIGCVWAADRDCAGDDLKVLQQFAACFLETLPAQEE
Sbjct: 661 QKLKAKEWDEFLAKGKRFRVLQPVKIGCVWAADRDCAGDDLKVLQQFAACFLETLPAQEE 720
Query: 721 QTPKASKRERRDEQILAQLLPLLHGNVNGSKVIIREFQEHCRRGLLSNHTGSPRSPSTTY 780
QTPKASKRERRDEQILAQLLPLLHGNVNGSKVIIREFQEHCRRGLLSNHTGSPRSPSTTY
Sbjct: 721 QTPKASKRERRDEQILAQLLPLLHGNVNGSKVIIREFQEHCRRGLLSNHTGSPRSPSTTY 780
Query: 781 LHTPTPSEDAAIPSKSRLKRLISENSVYEKRPDFRMCWYVHPQVLQSFQQEHLPVPCQWS 840
LHTPTPSEDAAIPSKSRLKRLISENSVYEKRPDFRMCWYVHPQVLQSFQQEHLPVPCQWS
Sbjct: 781 LHTPTPSEDAAIPSKSRLKRLISENSVYEKRPDFRMCWYVHPQVLQSFQQEHLPVPCQWS 840
Query: 841 YVTSVPSAPKEDSGSVPSTGPSQGTPISLKRKSAGSMCITQFMKKRRHDGQIGAEDMDGF 900
YVTSVPSAPKEDSGSVPSTGPSQGTPISLKRKSAGSMCITQFMKKRRHDGQIGAEDMDGF
Sbjct: 841 YVTSVPSAPKEDSGSVPSTGPSQGTPISLKRKSAGSMCITQFMKKRRHDGQIGAEDMDGF 900
Query: 901 QADTEEEEEEEGDCMIVDVPDAAEVQAPCGAASGAGGGVGVDTGKATLTASPLGAS 956
QADTEEEEEEEGDCMIVDVPDAAEVQAPCGAASGAGGGVGVDTGKATLTASPLGAS
Sbjct: 901 QADTEEEEEEEGDCMIVDVPDAAEVQAPCGAASGAGGGVGVDTGKATLTASPLGAS 956
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 83.6 bits (205), Expect = 8e-16
Identities = 48/147 (32%), Positives = 88/147 (59%), Gaps = 9/147 (6%)
Query: 321 ITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAK-RAKEEAKKKKEEEK 379
I+K + +E+ K R +R++ + ++ + + ER +KEK K + + R KE +K+KE EK
Sbjct: 25 ISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREK 84
Query: 380 ELKE-------KERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLR 432
+ KE K ++EK++++ K++ ++R K++ RKER+ + + E KRKK +K+ R
Sbjct: 85 QRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRR 144
Query: 433 EEEKRIKAEKAEITRFFQKPKTPQAPK 459
+E KR K E+ + R +K K + K
Sbjct: 145 KERKREK-ERGKRERKRKKRKKEEREK 170
Score = 80.9 bits (198), Expect = 5e-15
Identities = 45/124 (36%), Positives = 78/124 (62%), Gaps = 5/124 (4%)
Query: 319 RRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEE 378
R +K +G EK K ++ +ER ++ + R ERE++ K + E +R K + +KKK E
Sbjct: 50 REKERKRERGKKEKKK---RKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRER 106
Query: 379 KELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRI 438
K+ +ER++K+E+ E+E+ KQR + +R+K R++ + + E KR+KE KR R+ +KR
Sbjct: 107 KQRGRRERKKKKERKERERENKQRRERKRKKRRKK--KRRKERKREKERGKRERKRKKRK 164
Query: 439 KAEK 442
K E+
Sbjct: 165 KEER 168
Score = 79.3 bits (194), Expect = 2e-14
Identities = 48/130 (36%), Positives = 76/130 (58%), Gaps = 8/130 (6%)
Query: 320 RITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEK 379
R K+ K EK K ++ R K+ K R ERE + K + E KR K KK+++E K
Sbjct: 89 RREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148
Query: 380 ELKEKERRE----KREKDEKEKAE----KQRLKEERRKERQEALEAKLEEKRKKEEEKRL 431
KE+ +RE KR+K+E+EK K+R KE RKER+E + + +E+RKK+E K+
Sbjct: 149 REKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKD 208
Query: 432 REEEKRIKAE 441
R+ +++ ++
Sbjct: 209 RKTDRQTDSQ 218
Score = 76.6 bits (187), Expect = 1e-13
Identities = 46/125 (36%), Positives = 80/125 (64%), Gaps = 4/125 (3%)
Query: 323 KKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKE-EEKEL 381
KK +G E+ + R +R+++R ++ K R +R++++K +E +R + E KKKKE +E+E
Sbjct: 67 KKRERGK-ERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERER 125
Query: 382 KEKERRE-KREKDEKEKAEKQRLKE-ERRKERQEALEAKLEEKRKKEEEKRLREEEKRIK 439
+ K+RRE KR+K K+K K+R +E ER K ++ + K EE+ KK E R +++R +
Sbjct: 126 ENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERER 185
Query: 440 AEKAE 444
E+ E
Sbjct: 186 KERRE 190
Score = 74.7 bits (182), Expect = 4e-13
Identities = 41/122 (33%), Positives = 78/122 (63%), Gaps = 5/122 (4%)
Query: 327 KGSTEKNKLRLQRDQERLGK-QLKLRAEREEKE---KLKEEAKRAKEEAKKKKEEEKELK 382
K ++ K + +R++++ G+ + K + ER+E+E K + E KR K KK+++E K K
Sbjct: 92 KERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREK 151
Query: 383 EKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEK 442
E+ +RE++ K +++K E+++ +E RKER++ E K +RKKE +K R++++R K K
Sbjct: 152 ERGKRERKRK-KRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRK 210
Query: 443 AE 444
+
Sbjct: 211 TD 212
Score = 70.5 bits (171), Expect = 7e-12
Identities = 40/131 (30%), Positives = 76/131 (58%), Gaps = 8/131 (6%)
Query: 327 KGSTEKNKLRLQRDQERLGKQLKLRAEREE-KEKLKEEAKRAKEEAK------KKKEEEK 379
+G E+ K + ++++ER KQ + R ++ K+K ++E KR KE K K+K+EE+
Sbjct: 109 RGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEER 168
Query: 380 ELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIK 439
E K++ER K K E+E+ E++ K+ER+KER++ E K + K ++ + ++ +
Sbjct: 169 E-KKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESA 227
Query: 440 AEKAEITRFFQ 450
+ +T F+
Sbjct: 228 FNRVTVTGVFR 238
Score = 66.6 bits (161), Expect = 1e-10
Identities = 37/114 (32%), Positives = 71/114 (62%), Gaps = 2/114 (1%)
Query: 320 RITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEK 379
R KK K +NK R +R +++ K+ + + + EKE+ K E KR K + K+++E+++
Sbjct: 114 RKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRK-KEEREKKR 172
Query: 380 ELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLRE 433
E KER+++RE+ E+ + +K+R K+ERRK+++ + K + + + + LRE
Sbjct: 173 ERNRKERKKERERKERRERKKER-KKERRKKKERKKDRKTDRQTDSQVFRPLRE 225
Score = 52.8 bits (125), Expect = 2e-06
Identities = 32/96 (33%), Positives = 60/96 (62%), Gaps = 12/96 (12%)
Query: 319 RRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAER--EEKEKLKEEAKRAKEEAKKKKE 376
+R +K K +K + +R++ER GK+ + R +R EE+EK +E + +KE
Sbjct: 129 QRRERKRKKRRKKKRRKERKREKER-GKRERKRKKRKKEEREKKRE---------RNRKE 178
Query: 377 EEKELKEKERREKREKDEKEKAEKQRLKEERRKERQ 412
+KE + KERRE++++ +KE+ +K+ K++R+ +RQ
Sbjct: 179 RKKERERKERRERKKERKKERRKKKERKKDRKTDRQ 214
Score = 52.0 bits (123), Expect = 3e-06
Identities = 29/95 (30%), Positives = 52/95 (54%)
Query: 320 RITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEK 379
R KK K K + R + +R K+ K + E EK++ + +R KE +K++ E K
Sbjct: 133 RKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERK 192
Query: 380 ELKEKERREKREKDEKEKAEKQRLKEERRKERQEA 414
+ ++KERR+K+E+ + K ++Q + R R+ A
Sbjct: 193 KERKKERRKKKERKKDRKTDRQTDSQVFRPLRESA 227
Score = 42.0 bits (97), Expect = 0.003
Identities = 23/82 (28%), Positives = 50/82 (60%), Gaps = 2/82 (2%)
Query: 319 RRITKKFVKGSTEKNKLRLQRDQERLGKQLK-LRAEREEKEKLKEEAKRAKEEAKKKKEE 377
RR K+ + EK + + +R +++ K+ + + ER KE+ KE ++ + E KK++++
Sbjct: 138 RRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKK 197
Query: 378 EKELKEKERREKREKDEKEKAE 399
E+ K+KER++ R+ D + ++
Sbjct: 198 ERR-KKKERKKDRKTDRQTDSQ 218
Score = 32.7 bits (73), Expect = 1.7
Identities = 23/90 (25%), Positives = 44/90 (48%), Gaps = 1/90 (1%)
Query: 365 KRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRK-ERQEALEAKLEEKR 423
K A K E ++ K + + +K+R + E+RK ER++ + + +K
Sbjct: 3 KAISSRAAVKLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKE 62
Query: 424 KKEEEKRLREEEKRIKAEKAEITRFFQKPK 453
KK+ +KR R +E+ K ++ E R ++ K
Sbjct: 63 KKKRKKRERGKERERKRKEREKQRKERREK 92
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 82.4 bits (202), Expect = 2e-15
Identities = 45/138 (32%), Positives = 85/138 (61%), Gaps = 4/138 (2%)
Query: 319 RRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEE 378
+R +K K EK K + + +ER G+ K ERE KE+ K E ++ +E K+++E+E
Sbjct: 99 KRRREKENKEGEEKEKRKKKEKKER-GRTSKEGKERERKEERKREERKERERKKEEREKE 157
Query: 379 KELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEK---RLREEE 435
+E KE+++RE+++ EKE+ K++ ++ER+K + E K E +RK+ E+ R ++EE
Sbjct: 158 RERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEE 217
Query: 436 KRIKAEKAEITRFFQKPK 453
++ + +K T + +K +
Sbjct: 218 RKKERQKDRQTNWREKER 235
Score = 77.8 bits (190), Expect = 5e-14
Identities = 49/126 (38%), Positives = 79/126 (62%), Gaps = 9/126 (7%)
Query: 319 RRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEE 378
R +K +G EK R + ++ER K R E+E KE +E+ KR K+E K++
Sbjct: 73 REKERKRERGKKEKKGERKKEERERK----KRRREKENKEG-EEKEKRKKKEKKERGRTS 127
Query: 379 KELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKR--KKEEEKRLREEEK 436
KE KE+ER+E+R+++E++ E++R KEER KER+ K E K+ +KEEE++ +E ++
Sbjct: 128 KEGKERERKEERKREERK--ERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKE 185
Query: 437 RIKAEK 442
R K E+
Sbjct: 186 RKKRER 191
Score = 77.4 bits (189), Expect = 6e-14
Identities = 46/129 (35%), Positives = 78/129 (60%), Gaps = 14/129 (10%)
Query: 330 TEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEE-KELKEKERRE 388
+E+ K R +R++ + ++ + + ER +KEK E K +E K+++E+E KE +EKE+R+
Sbjct: 57 SERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRK 116
Query: 389 KREKDE--------KEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLR-----EEE 435
K+EK E KE+ K+ K E RKER+ E + +E+ +KE +KR R +EE
Sbjct: 117 KKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEE 176
Query: 436 KRIKAEKAE 444
+R + E+ E
Sbjct: 177 ERKEKERKE 185
Score = 77.4 bits (189), Expect = 6e-14
Identities = 48/129 (37%), Positives = 80/129 (62%), Gaps = 5/129 (3%)
Query: 319 RRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRA-EREEKEKLKEEAKRAKEEAKKKKEE 377
R+ +K +G T K +R +ER ++ K R ++EE+EK +E +R K E K+ E+
Sbjct: 115 RKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEK 174
Query: 378 EKELKEKER--REKREKDEKEKAEKQRLKE--ERRKERQEALEAKLEEKRKKEEEKRLRE 433
E+E KEKER R+KRE++ KE+ +++ KE ER+KER++ E K E ++ ++ R +E
Sbjct: 175 EEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKE 234
Query: 434 EEKRIKAEK 442
KR + E+
Sbjct: 235 RGKRERKER 243
Score = 76.3 bits (186), Expect = 1e-13
Identities = 40/125 (32%), Positives = 75/125 (60%), Gaps = 1/125 (0%)
Query: 322 TKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKEL 381
T+K K E + + +R++E+ ++ + +RE +K K+ ++ +E +KK+ EKE
Sbjct: 47 TRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKEN 106
Query: 382 KEKERREKREKDE-KEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKA 440
KE E +EKR+K E KE+ + +ER ++ + E + E +RKKEE ++ RE ++R K
Sbjct: 107 KEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKR 166
Query: 441 EKAEI 445
E+ ++
Sbjct: 167 ERKQV 171
Score = 74.3 bits (181), Expect = 5e-13
Identities = 45/139 (32%), Positives = 85/139 (61%), Gaps = 3/139 (2%)
Query: 323 KKFVKGSTEKNKL-RLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKE-EAKKKKEEEKE 380
KK KG +K + R +R +E+ K+ + + +R++KEK KE + +KE + +++KEE K
Sbjct: 83 KKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEK-KERGRTSKEGKERERKEERKR 141
Query: 381 LKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKA 440
+ KER K+E+ EKE+ K+R K ER++ ++ E K +E++++++ +R R+E K+ +
Sbjct: 142 EERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERE 201
Query: 441 EKAEITRFFQKPKTPQAPK 459
K R ++ K + K
Sbjct: 202 RKERRERKKERKKKEERKK 220
Score = 66.2 bits (160), Expect = 1e-10
Identities = 36/102 (35%), Positives = 69/102 (67%), Gaps = 4/102 (3%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAERE--EKEKLKEEAKRAKEEAKKKKEEEKELKEKERRE 388
E+ + + +R++ER K+ K R ++ EKE+ ++E +R KE K+++ ++ KE+ER+E
Sbjct: 146 ERERKKEEREKERERKERKKRERKQVGEKEEERKEKER-KERKKRERNRKERKKERERKE 204
Query: 389 KREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKR 430
+RE+ +KE+ +K+ K+ER+K+RQ K KR+++E K+
Sbjct: 205 RRER-KKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 64.3 bits (155), Expect = 5e-10
Identities = 43/156 (27%), Positives = 82/156 (52%), Gaps = 20/156 (12%)
Query: 304 KQHSSTSPFPTSTPLRRITKKFV-KGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKE 362
K SS + +T L+ ++ + K T+ R++ER ++ +E K++ +
Sbjct: 3 KAISSRAAVKLNTELQMVSCSHISKPCTQPGWQSEIRERER-----EIETRKEGKKERES 57
Query: 363 EAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEK 422
E K+ + E +K+K E ++ +++ER +K +K E++K E++R K R KE +E E + +K
Sbjct: 58 ERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKK 117
Query: 423 RKKEE--------------EKRLREEEKRIKAEKAE 444
++K+E E+R REE K + +K E
Sbjct: 118 KEKKERGRTSKEGKERERKEERKREERKERERKKEE 153
Score = 62.8 bits (151), Expect = 1e-09
Identities = 42/109 (38%), Positives = 65/109 (59%), Gaps = 10/109 (9%)
Query: 345 GKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLK 404
G Q ++R ERE + + ++E K+ +E +KK+ E+E K K REK K E+ K EK K
Sbjct: 33 GWQSEIR-EREREIETRKEGKKERESERKKERRERE-KRKREREKERKRERGKKEK---K 87
Query: 405 EERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITRFFQKPK 453
ER+KE +E +++R+++E K E+EKR K EK E R ++ K
Sbjct: 88 GERKKEERER-----KKRRREKENKEGEEKEKRKKKEKKERGRTSKEGK 131
Score = 42.0 bits (97), Expect = 0.003
Identities = 23/94 (24%), Positives = 50/94 (53%), Gaps = 4/94 (4%)
Query: 378 EKELKEKER----REKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLRE 433
+ E++E+ER R++ +K+ + + +K+R + E+RK +E + K++K+ E++ E
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
Query: 434 EEKRIKAEKAEITRFFQKPKTPQAPKTLAGSCGK 467
E++ + + E +K K + K G K
Sbjct: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSK 128
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 79.7 bits (195), Expect = 1e-14
Identities = 41/121 (33%), Positives = 82/121 (67%), Gaps = 2/121 (1%)
Query: 323 KKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELK 382
KK K TE+ + + +E K+ K + +R+EK K KE+ K+ KE K+K++EE+E K
Sbjct: 3 KKKKKKETEETE-ETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61
Query: 383 EK-ERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAE 441
K +R++K+E++E+E+ E++ +E+ +E++E K ++KR+++EE+ +++++R K +
Sbjct: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTK 121
Query: 442 K 442
K
Sbjct: 122 K 122
Score = 76.6 bits (187), Expect = 1e-13
Identities = 36/108 (33%), Positives = 73/108 (67%)
Query: 322 TKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKEL 381
T++ + ++ K + +R ++R K+ K + + EK K KEE ++ ++ +KKK+EE+E
Sbjct: 16 TEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEER 75
Query: 382 KEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEK 429
+E+E E+ EK+E+EK E +R K+++++ R+E E K +++R+K ++K
Sbjct: 76 EEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
Score = 73.9 bits (180), Expect = 7e-13
Identities = 40/114 (35%), Positives = 72/114 (63%), Gaps = 2/114 (1%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREK- 389
+K K + + ++ ++ + E+E K K K + KR ++E KKK +E ++ KEKE EK
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61
Query: 390 -REKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEK 442
+ K +K+K E++R +EE +E ++ E K E +R+K+++KR R+EE+ K +K
Sbjct: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKK 115
Score = 72.0 bits (175), Expect = 2e-12
Identities = 41/119 (34%), Positives = 75/119 (63%), Gaps = 10/119 (8%)
Query: 346 KQLKLRAEREEKEKLKE-------EAKRAKEEAKKKKEEEKELKEKE---RREKREKDEK 395
K+ K + E EE E+ +E E KR ++ +K+KE+EK+ K KE R+EK E+++K
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61
Query: 396 EKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITRFFQKPKT 454
K ++++ KEE +E +E E + +E+ +KEE +R ++++KR + E+ E + ++ KT
Sbjct: 62 RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKT 120
Score = 69.3 bits (168), Expect = 2e-11
Identities = 35/90 (38%), Positives = 63/90 (70%), Gaps = 1/90 (1%)
Query: 355 EEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEA 414
++K+K K+E + +E + ++EEEKE K KE+R+++ K EKEK +K + E+R+++ +E
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRK-EKEKKKKTKETEKRKEKEEEE 59
Query: 415 LEAKLEEKRKKEEEKRLREEEKRIKAEKAE 444
+ K + K+KKEEE+R EEE+ + ++ E
Sbjct: 60 KKRKRKRKKKKEEEEREEEEEEEEEEKEEE 89
Score = 41.2 bits (95), Expect = 0.005
Identities = 24/68 (35%), Positives = 39/68 (57%), Gaps = 5/68 (7%)
Query: 391 EKDEKEKAEKQRLKEERRKERQEALEAKLEEKRK-----KEEEKRLREEEKRIKAEKAEI 445
+K +K+K E + +E E +E E K +EKRK KE++K+ +E EKR + E+ E
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 446 TRFFQKPK 453
R ++ K
Sbjct: 61 KRKRKRKK 68
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 78.6 bits (192), Expect = 3e-14
Identities = 71/250 (28%), Positives = 128/250 (51%), Gaps = 41/250 (16%)
Query: 246 LAVRPPQIKSLPATPQGKNMTPESEVLES----FPEEDSVLSH--------SSLSSPSST 293
L +PP + A+P+G+ E E ES PE+ S ++ +SP+ +
Sbjct: 490 LPPKPPSPRGTTASPKGRVRRKE-EAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPS 548
Query: 294 SSPEGPPAPPKQHSSTSPFPTST--------PLRRIT-KKFVKGSTEKN--------KLR 336
+P PAPP++ + PT P +T K + G+T++ K R
Sbjct: 549 PAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRR 608
Query: 337 LQRDQ-ERLGKQLKLRAEREEK---EKLKEEAK-RAKEEAKKKKEEEKELKEKERREKRE 391
R+Q ER ++ +L+AER+++ E+L EA+ RA+ EA+ ++ EE+E +EK + E+ E
Sbjct: 609 QAREQREREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEE 668
Query: 392 KD----EKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITR 447
++ +KE+AE + +E R+ + + +E+ ++E KRL E KR + K+E++
Sbjct: 669 QERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTR--KSEVSE 726
Query: 448 FFQKPKTPQA 457
QK + +A
Sbjct: 727 TKQKQDSKEA 736
Score = 63.2 bits (152), Expect = 1e-09
Identities = 58/217 (26%), Positives = 96/217 (44%), Gaps = 28/217 (12%)
Query: 245 ILAVRPPQIKSLPATPQGKNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGP----- 299
++A PP+ + P P S ++ P + ++ SS PE P
Sbjct: 17 VVARTPPEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEPESPSGQVG 76
Query: 300 --PAPPKQHSSTS------PFPTST------PLRRITKKFVKGSTEKNKLRLQRDQERLG 345
PAPP++ S +S P P + P RR ++ + +++ ++ G
Sbjct: 77 PRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSPPTKQEVKKAG 136
Query: 346 KQLKLRAEREEKEKLKEEAKRAKEEAKKKKEE-EKELKEKERREKREKDEKEKAEKQRLK 404
++ KL ER E+ RAK A KK EKE K K REK+ ++ + + E+QRLK
Sbjct: 137 ERHKLAKERREE--------RAKYLAAKKAVWLEKEEKAKALREKQLQERRRRLEEQRLK 188
Query: 405 EERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAE 441
E+R+ E + + EK K+ E ++ K+ AE
Sbjct: 189 AEQRRAALEERQRQKLEKNKERYEAAIQRSVKKTWAE 225
Score = 45.1 bits (105), Expect = 3e-04
Identities = 48/175 (27%), Positives = 74/175 (42%), Gaps = 28/175 (16%)
Query: 290 PSSTSSPEGPPAPPKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLK 349
P SPEG P+PP S P + P T +K +T +L L+ E Q+
Sbjct: 23 PEPRPSPEGDPSPPPPPMSAL-VPDTPP---DTPPAMKNATSSKQLPLE--PESPSGQVG 76
Query: 350 LRAEREEKEKLKEEAK-----------RAKEEAKKKKEEEKELKEKERREKREKDEKEKA 398
R ++E EAK R ++ + +++ K+
Sbjct: 77 PRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSPPTKQEVKKAG 136
Query: 399 EKQRLKEERRKERQEALEAKLEEKRKKEEE-KRLRE----------EEKRIKAEK 442
E+ +L +ERR+ER + L AK +KEE+ K LRE EE+R+KAE+
Sbjct: 137 ERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRLEEQRLKAEQ 191
Score = 38.5 bits (88), Expect = 0.030
Identities = 29/99 (29%), Positives = 54/99 (54%), Gaps = 8/99 (8%)
Query: 338 QRDQERLGKQLKLRAE---REEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDE 394
Q +QERL KQ K AE REE E+ + E ++ ++ +++++E ++ E+ + R+ +
Sbjct: 666 QEEQERLQKQ-KEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEV 724
Query: 395 KEKAEKQRLKEERRK----ERQEALEAKLEEKRKKEEEK 429
E +KQ KE E +A+EA+ +K+ +K
Sbjct: 725 SETKQKQDSKEANANGSSPEPVKAVEARSPGLQKEAVQK 763
Score = 31.6 bits (70), Expect = 3.7
Identities = 19/83 (22%), Positives = 43/83 (51%), Gaps = 6/83 (7%)
Query: 373 KKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLR 432
+++ E +++KE+++K ++EKEK+ L ER +++++L A R +
Sbjct: 404 RRRPEASPVQKKEKKDKERENEKEKS---ALARERSLKKRQSLPA---SPRARLSASTAS 457
Query: 433 EEEKRIKAEKAEITRFFQKPKTP 455
E + KA + + + +P +P
Sbjct: 458 ELSPKSKARPSSPSTSWHRPASP 480
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 77.8 bits (190), Expect = 5e-14
Identities = 48/115 (41%), Positives = 73/115 (63%), Gaps = 13/115 (11%)
Query: 341 QERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEK 400
+E+ Q + R E EE+E+++EE KRA EE ++ KEEEK E ER+ +E++++ E+
Sbjct: 298 EEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAE-ERQRIKEEEKRAAEER 356
Query: 401 QRLKEERRK---ERQEALEAKLEEKRKKEEEKRLRE--------EEKRIKAEKAE 444
QR+KEE ++ ERQ A A+ EEK K EE+KR ++ +E +IK EK E
Sbjct: 357 QRIKEEEKRAAEERQRA-RAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVE 410
Score = 77.4 bits (189), Expect = 6e-14
Identities = 38/112 (33%), Positives = 68/112 (60%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKR 390
E++K R + ++ RL + + R + E+ +K+ +E R + E K +E + + +ER R
Sbjct: 259 EEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMR 318
Query: 391 EKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEK 442
E++++ E+QR+KEE ++ +E K EEKR EE +R++EEEKR E+
Sbjct: 319 EEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEER 370
Score = 77.0 bits (188), Expect = 8e-14
Identities = 47/140 (33%), Positives = 78/140 (55%), Gaps = 2/140 (1%)
Query: 338 QRDQERL-GKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKE 396
+ D+ER ++ +L AE E+ K +++ K A E A+ + EE+ +E+ERRE E+ E+
Sbjct: 259 EEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEER-ERM 317
Query: 397 KAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITRFFQKPKTPQ 456
+ E++R EER++ ++E A E +R KEEEKR EE +RIK E+ Q+ + +
Sbjct: 318 REEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEE 377
Query: 457 APKTLAGSCGKFAPFEIKEH 476
K + E K+H
Sbjct: 378 EEKAKVEEQKRNKQLEEKKH 397
Score = 73.6 bits (179), Expect = 8e-13
Identities = 41/119 (34%), Positives = 71/119 (59%), Gaps = 2/119 (1%)
Query: 336 RLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEK 395
R++ +Q++ + R E EEK +E +R EE ++ +EEEK E ER+ +E++++
Sbjct: 279 RIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAE-ERQRIKEEEKR 337
Query: 396 EKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLR-EEEKRIKAEKAEITRFFQKPK 453
E+QR+KEE ++ +E K EEKR EE +R R EEE++ K E+ + + ++ K
Sbjct: 338 AAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKK 396
Score = 66.2 bits (160), Expect = 1e-10
Identities = 40/144 (27%), Positives = 75/144 (52%), Gaps = 4/144 (2%)
Query: 314 TSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKK 373
T + + G + + + ++E+ ++ + EE++K + EA+RA+ EA++
Sbjct: 217 TESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEE 276
Query: 374 ----KKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEK 429
K E++K++ ++ R + E+ + ++R EER + R+E A E +R KEEEK
Sbjct: 277 RERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEK 336
Query: 430 RLREEEKRIKAEKAEITRFFQKPK 453
R EE +RIK E+ Q+ K
Sbjct: 337 RAAEERQRIKEEEKRAAEERQRIK 360
Score = 65.1 bits (157), Expect = 3e-10
Identities = 35/130 (26%), Positives = 74/130 (56%), Gaps = 12/130 (9%)
Query: 327 KGSTEKNKLRLQRDQERLGKQLKLRAER------------EEKEKLKEEAKRAKEEAKKK 374
K + ++ + R ++ER+ ++ K AE EE++++KEE KRA EE ++
Sbjct: 300 KAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRI 359
Query: 375 KEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREE 434
KEEEK E+ +R + E++EK K E+Q+ ++ +++ E K++ ++ +++ +
Sbjct: 360 KEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVN 419
Query: 435 EKRIKAEKAE 444
EK+ + +K +
Sbjct: 420 EKKAQEDKLQ 429
Score = 56.6 bits (135), Expect = 1e-07
Identities = 51/197 (25%), Positives = 89/197 (45%), Gaps = 34/197 (17%)
Query: 270 EVLESFPEEDSVLSHSSLSSPS-----STSSPEGPPAPPKQHSSTSPFP---TSTPLRRI 321
E LE E D ++ +SLS PS T+ E K S + T T +
Sbjct: 113 EALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSY 172
Query: 322 TKKFVKGSTEKNKLRLQRDQERLGK---------QLKLRAEREEKEKLKE-------EAK 365
K + + E K ++++E K Q+++ E + E +E +
Sbjct: 173 QKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQ 232
Query: 366 RAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKK 425
+ EE K+++E E+ E EK E+++KE+AE +R + LEA+ E+ K
Sbjct: 233 ISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERAR----------LEAEERERIKA 282
Query: 426 EEEKRLREEEKRIKAEK 442
E++K++ +E RI+AE+
Sbjct: 283 EQDKKIADERARIEAEE 299
Score = 56.6 bits (135), Expect = 1e-07
Identities = 36/114 (31%), Positives = 65/114 (57%), Gaps = 8/114 (7%)
Query: 326 VKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKE 385
V+ +LR +R + + KL+ +++E EE K+ +EE +K EEE++ +++E
Sbjct: 530 VEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQE 589
Query: 386 RREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIK 439
+++ ++E+ EK+RLKEE + R EA EKR+K E L +++K K
Sbjct: 590 EADRKLREEE---EKRRLKEEIERRRAEA-----AEKRQKMPEDGLSDDKKPFK 635
Score = 55.5 bits (132), Expect = 2e-07
Identities = 47/179 (26%), Positives = 86/179 (48%), Gaps = 15/179 (8%)
Query: 352 AEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQR---LKEERR 408
A + E K EE +R + E + EE ++LK+K++ E +E +K ++R L+EE +
Sbjct: 527 APQVEAGKRLEELRRRRGETES--EEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQ 584
Query: 409 KERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITRFFQKPKTPQAPKTLAGSCGKF 468
+ +QE + KL R++EE++RL+EE +R +AE AE + + K K
Sbjct: 585 RRKQEEADRKL---REEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKG 641
Query: 469 APFEIKEHMVLAPRR-------RTAFHPDLCSQLDQLLQQQSGEFSFLKDLKGRQPLRS 520
+ +I+E + ++ + S++D L+Q + K K +P S
Sbjct: 642 SSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPAAS 700
Score = 52.8 bits (125), Expect = 2e-06
Identities = 32/126 (25%), Positives = 74/126 (58%), Gaps = 3/126 (2%)
Query: 319 RRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEE 378
+RI ++ + + E+ +++ + ++ ++ + RAE EEK K++E+ + + E KK +E
Sbjct: 343 QRIKEEEKRAAEERQRIK-EEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQE 401
Query: 379 KELKEKERREKREKD--EKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEK 436
++K ++ +K E ++KA++ +L+ K++ E K++ KR+K +E + +++
Sbjct: 402 TKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKE 461
Query: 437 RIKAEK 442
IK EK
Sbjct: 462 EIKDEK 467
Score = 49.7 bits (117), Expect = 1e-05
Identities = 44/146 (30%), Positives = 75/146 (51%), Gaps = 19/146 (13%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAE-----REEKEKLKEEAKRAK--EEAKKKKEEEKELKE 383
++ + R +++R+ ++ K AE +EE+++ EE +RA+ EE K K EE+K K+
Sbjct: 332 KEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQ 391
Query: 384 KERREKREKDEKEKAEKQRLKEE----RRKERQE------ALEAKLEEKRKKEEEKRLRE 433
E ++ ++ K K EK K E K+ QE L+ + EEK K + KR +
Sbjct: 392 LEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKL 451
Query: 434 EEKRIKAEKAEITRFFQKPKTPQAPK 459
+E + +K EI +K K + PK
Sbjct: 452 QEDKPTFKKEEIKD--EKIKKDKEPK 475
Score = 48.1 bits (113), Expect = 4e-05
Identities = 43/151 (28%), Positives = 73/151 (48%), Gaps = 15/151 (9%)
Query: 322 TKKFVKGSTEKNKL-RLQRDQERLGKQLKLRAEREEK-------EKLKEEAKRAKEEAKK 373
T V+G E L RL R +ER K+L+ ER+++ L ++R + + +
Sbjct: 84 TNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAE 143
Query: 374 KKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLRE 433
+ EKE K + R+E+ E +E E K K + R +A E K E+K K+EEE+ E
Sbjct: 144 NETTEKEEKSESRQERYEIEETETVTKSYQKNDWR----DAEENKKEDKEKEEEEE---E 196
Query: 434 EEKRIKAEKAEITRFFQKPKTPQAPKTLAGS 464
+ KR + ++ ++ T +T+ S
Sbjct: 197 KPKRGSIGENQVEVMVEEKTTESQEETVVMS 227
Score = 45.8 bits (107), Expect = 2e-04
Identities = 35/137 (25%), Positives = 67/137 (48%), Gaps = 19/137 (13%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKE------EEKELKEK 384
E+ + +R + R ++ K + E +++ K EE K A +E K K E E K + EK
Sbjct: 362 EEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEK 421
Query: 385 ERREKR-----------EKDEKEKAEKQRLKEERRKERQEAL--EAKLEEKRKKEEEKRL 431
+ +E + EK K +A++++L+E++ ++E + E ++K KEE K
Sbjct: 422 KAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSF 481
Query: 432 REEEKRIKAEKAEITRF 448
+ +K K++ F
Sbjct: 482 MDRKKGFTEVKSQNGEF 498
Score = 45.1 bits (105), Expect = 3e-04
Identities = 32/123 (26%), Positives = 66/123 (53%), Gaps = 4/123 (3%)
Query: 282 LSHSSLSSPSSTSSPEGPPAPPKQHSSTSP-FPTSTPLRRITKKFVKGSTEKNKLRLQRD 340
++H + ++ S P G + + + +P L + ++ + +E+ + Q+
Sbjct: 499 MTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQ 558
Query: 341 QERLGKQLKLRAEREEKEKL--KEEAKRAKEEAKKK-KEEEKELKEKERREKREKDEKEK 397
QE + +L+ +REE+ K+ +EE +R +EEA +K +EEE++ + KE E+R + EK
Sbjct: 559 QEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEK 618
Query: 398 AEK 400
+K
Sbjct: 619 RQK 621
Score = 44.3 bits (103), Expect = 6e-04
Identities = 32/127 (25%), Positives = 63/127 (49%), Gaps = 5/127 (3%)
Query: 323 KKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELK 382
+K K K +++ D+++ ++K + KLK + + KE +
Sbjct: 466 EKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAE 525
Query: 383 ---EKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKR--LREEEKR 437
+ E ++ E+ + + E + + E+ K++Q+ +LEE +KK EE+R L EEE+R
Sbjct: 526 GAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQR 585
Query: 438 IKAEKAE 444
K E+A+
Sbjct: 586 RKQEEAD 592
Score = 39.7 bits (91), Expect = 0.014
Identities = 44/174 (25%), Positives = 76/174 (43%), Gaps = 60/174 (34%)
Query: 332 KNKLRLQRDQERLGKQLKLRAER--------EEKEKLKEEAKRAKEEAKKKKEEEKELKE 383
+ +LR Q+ +E ++L AER +E+E +E +RA++E ++K+EE+ L +
Sbjct: 7 RRELRRQKREE-----MRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQ 61
Query: 384 -----KERREKREKDEKEKA----------------EKQRLKEERRKER-QEALEAKLE- 420
+ + DE+ K E+ +EERR++R QEALE + E
Sbjct: 62 VTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEF 121
Query: 421 -----------------------EKRKKEEEKRLREEEKRIKAEKAEITRFFQK 451
E +KEE+ R+E I+ E +T+ +QK
Sbjct: 122 DPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIE-ETETVTKSYQK 174
Score = 36.2 bits (82), Expect = 0.15
Identities = 20/61 (32%), Positives = 36/61 (59%), Gaps = 5/61 (8%)
Query: 362 EEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEE 421
++ +R +E ++K+EE + E+ ++ + DE+E A +E RR+ RQE L K EE
Sbjct: 2 DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAA-----RERRRRARQERLRQKQEE 56
Query: 422 K 422
+
Sbjct: 57 E 57
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 77.4 bits (189), Expect = 6e-14
Identities = 60/204 (29%), Positives = 110/204 (53%), Gaps = 12/204 (5%)
Query: 243 QDILAVRPPQIKSLPATPQGKNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAP 302
Q LA+ Q ++L +N+ P S P+ S+ +S + EG
Sbjct: 647 QQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVW--EGGSVW 704
Query: 303 PKQHSSTSPFPTSTPLRRITK-KFVKGSTEKNK--LRLQRDQERLGKQLKLRAEREEKEK 359
+T+P P L+++ K K K E+ + +R +R++E +Q +LR ++EE
Sbjct: 705 DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEI-- 762
Query: 360 LKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKL 419
+R +EE +K++EEE+ + K+ R + E+E A +++ +EE R++++EAL +L
Sbjct: 763 ----LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALR-RL 817
Query: 420 EEKRKKEEEKRLREEEKRIKAEKA 443
EE+R++EEE+R +EE R + E+A
Sbjct: 818 EERRREEEERRKQEELLRKQEEEA 841
Score = 60.8 bits (146), Expect = 6e-09
Identities = 42/134 (31%), Positives = 79/134 (58%), Gaps = 15/134 (11%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEA------KRAKEEAKKKKEEEKELKEK 384
++ LR QR+QE + LR +REE+E+ ++E +R +EE +++K+EE K++
Sbjct: 784 QEEALRRQREQE-----IALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE 838
Query: 385 ERREKREKDEKEKAEKQRLKEERRKERQEA--LEAKLEEKRKKEEEKRLREEEKRIKAEK 442
E K ++E+E ++RL+E R + +EA L + EE+++KE E + ++E R + ++
Sbjct: 839 EEAAKWAREEEE--AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQ 896
Query: 443 AEITRFFQKPKTPQ 456
E R Q+ + Q
Sbjct: 897 QEALRRLQQQQQQQ 910
Score = 58.5 bits (140), Expect = 3e-08
Identities = 41/139 (29%), Positives = 77/139 (55%), Gaps = 17/139 (12%)
Query: 318 LRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKE------KLKEEAKRAKEEA 371
LRR ++ ++ E+ + R R++E L ++ + A R ++E + +EE +R ++E
Sbjct: 755 LRRQQEEILRRQQEEERKR--REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 812
Query: 372 KKKKEEEKELKEKERREKRE---KDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEE 428
++ EE+ +E+ERR++ E K E+E A+ R +EE ++ +E R +EE
Sbjct: 813 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE------NRLRMEEEA 866
Query: 429 KRLREEEKRIKAEKAEITR 447
RLR EE+ K ++ E+ R
Sbjct: 867 ARLRHEEEERKRKELEVQR 885
Score = 53.5 bits (127), Expect = 9e-07
Identities = 48/196 (24%), Positives = 97/196 (49%), Gaps = 8/196 (4%)
Query: 318 LRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEE 377
LRR ++ + ++ + Q+ +E L + + R E EE+ K +E ++ +EEA K E
Sbjct: 788 LRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWARE 847
Query: 378 EKELKEKERREKREKDEKEKAEKQRLKEER-RKERQEALEAKLEEKRKKEEE--KRLREE 434
E+E ++ E R + E+E A + +EER RKE + + +L +R++++E +RL+++
Sbjct: 848 EEE-AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQ 906
Query: 435 EKRIKAEKAEI---TRFFQKPKTPQAPKTLAGSCGKFAPFEIKEHMVLAPRRRTAFHPDL 491
+++ + + ++ + + Q+ T S + E + L +R +L
Sbjct: 907 QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQ-QREL 965
Query: 492 CSQLDQLLQQQSGEFS 507
L Q QQQ + S
Sbjct: 966 MKALQQQQQQQQQKLS 981
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 77.4 bits (189), Expect = 6e-14
Identities = 60/204 (29%), Positives = 110/204 (53%), Gaps = 12/204 (5%)
Query: 243 QDILAVRPPQIKSLPATPQGKNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAP 302
Q LA+ Q ++L +N+ P S P+ S+ +S + EG
Sbjct: 674 QQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVW--EGGSVW 731
Query: 303 PKQHSSTSPFPTSTPLRRITK-KFVKGSTEKNK--LRLQRDQERLGKQLKLRAEREEKEK 359
+T+P P L+++ K K K E+ + +R +R++E +Q +LR ++EE
Sbjct: 732 DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEI-- 789
Query: 360 LKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKL 419
+R +EE +K++EEE+ + K+ R + E+E A +++ +EE R++++EAL +L
Sbjct: 790 ----LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALR-RL 844
Query: 420 EEKRKKEEEKRLREEEKRIKAEKA 443
EE+R++EEE+R +EE R + E+A
Sbjct: 845 EERRREEEERRKQEELLRKQEEEA 868
Score = 60.8 bits (146), Expect = 6e-09
Identities = 42/134 (31%), Positives = 79/134 (58%), Gaps = 15/134 (11%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEA------KRAKEEAKKKKEEEKELKEK 384
++ LR QR+QE + LR +REE+E+ ++E +R +EE +++K+EE K++
Sbjct: 811 QEEALRRQREQE-----IALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE 865
Query: 385 ERREKREKDEKEKAEKQRLKEERRKERQEA--LEAKLEEKRKKEEEKRLREEEKRIKAEK 442
E K ++E+E ++RL+E R + +EA L + EE+++KE E + ++E R + ++
Sbjct: 866 EEAAKWAREEEE--AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQ 923
Query: 443 AEITRFFQKPKTPQ 456
E R Q+ + Q
Sbjct: 924 QEALRRLQQQQQQQ 937
Score = 58.5 bits (140), Expect = 3e-08
Identities = 41/139 (29%), Positives = 77/139 (55%), Gaps = 17/139 (12%)
Query: 318 LRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKE------KLKEEAKRAKEEA 371
LRR ++ ++ E+ + R R++E L ++ + A R ++E + +EE +R ++E
Sbjct: 782 LRRQQEEILRRQQEEERKR--REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 839
Query: 372 KKKKEEEKELKEKERREKRE---KDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEE 428
++ EE+ +E+ERR++ E K E+E A+ R +EE ++ +E R +EE
Sbjct: 840 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE------NRLRMEEEA 893
Query: 429 KRLREEEKRIKAEKAEITR 447
RLR EE+ K ++ E+ R
Sbjct: 894 ARLRHEEEERKRKELEVQR 912
Score = 53.5 bits (127), Expect = 9e-07
Identities = 48/196 (24%), Positives = 97/196 (49%), Gaps = 8/196 (4%)
Query: 318 LRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEE 377
LRR ++ + ++ + Q+ +E L + + R E EE+ K +E ++ +EEA K E
Sbjct: 815 LRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWARE 874
Query: 378 EKELKEKERREKREKDEKEKAEKQRLKEER-RKERQEALEAKLEEKRKKEEE--KRLREE 434
E+E ++ E R + E+E A + +EER RKE + + +L +R++++E +RL+++
Sbjct: 875 EEE-AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQ 933
Query: 435 EKRIKAEKAEI---TRFFQKPKTPQAPKTLAGSCGKFAPFEIKEHMVLAPRRRTAFHPDL 491
+++ + + ++ + + Q+ T S + E + L +R +L
Sbjct: 934 QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQ-QREL 992
Query: 492 CSQLDQLLQQQSGEFS 507
L Q QQQ + S
Sbjct: 993 MKALQQQQQQQQQKLS 1008
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 77.4 bits (189), Expect = 6e-14
Identities = 60/204 (29%), Positives = 110/204 (53%), Gaps = 12/204 (5%)
Query: 243 QDILAVRPPQIKSLPATPQGKNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAP 302
Q LA+ Q ++L +N+ P S P+ S+ +S + EG
Sbjct: 653 QQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVW--EGGSVW 710
Query: 303 PKQHSSTSPFPTSTPLRRITK-KFVKGSTEKNK--LRLQRDQERLGKQLKLRAEREEKEK 359
+T+P P L+++ K K K E+ + +R +R++E +Q +LR ++EE
Sbjct: 711 DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEI-- 768
Query: 360 LKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKL 419
+R +EE +K++EEE+ + K+ R + E+E A +++ +EE R++++EAL +L
Sbjct: 769 ----LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALR-RL 823
Query: 420 EEKRKKEEEKRLREEEKRIKAEKA 443
EE+R++EEE+R +EE R + E+A
Sbjct: 824 EERRREEEERRKQEELLRKQEEEA 847
Score = 60.8 bits (146), Expect = 6e-09
Identities = 42/134 (31%), Positives = 79/134 (58%), Gaps = 15/134 (11%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEA------KRAKEEAKKKKEEEKELKEK 384
++ LR QR+QE + LR +REE+E+ ++E +R +EE +++K+EE K++
Sbjct: 790 QEEALRRQREQE-----IALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE 844
Query: 385 ERREKREKDEKEKAEKQRLKEERRKERQEA--LEAKLEEKRKKEEEKRLREEEKRIKAEK 442
E K ++E+E ++RL+E R + +EA L + EE+++KE E + ++E R + ++
Sbjct: 845 EEAAKWAREEEE--AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQ 902
Query: 443 AEITRFFQKPKTPQ 456
E R Q+ + Q
Sbjct: 903 QEALRRLQQQQQQQ 916
Score = 58.5 bits (140), Expect = 3e-08
Identities = 41/139 (29%), Positives = 77/139 (55%), Gaps = 17/139 (12%)
Query: 318 LRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKE------KLKEEAKRAKEEA 371
LRR ++ ++ E+ + R R++E L ++ + A R ++E + +EE +R ++E
Sbjct: 761 LRRQQEEILRRQQEEERKR--REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 818
Query: 372 KKKKEEEKELKEKERREKRE---KDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEE 428
++ EE+ +E+ERR++ E K E+E A+ R +EE ++ +E R +EE
Sbjct: 819 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE------NRLRMEEEA 872
Query: 429 KRLREEEKRIKAEKAEITR 447
RLR EE+ K ++ E+ R
Sbjct: 873 ARLRHEEEERKRKELEVQR 891
Score = 53.5 bits (127), Expect = 9e-07
Identities = 48/196 (24%), Positives = 97/196 (49%), Gaps = 8/196 (4%)
Query: 318 LRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEE 377
LRR ++ + ++ + Q+ +E L + + R E EE+ K +E ++ +EEA K E
Sbjct: 794 LRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWARE 853
Query: 378 EKELKEKERREKREKDEKEKAEKQRLKEER-RKERQEALEAKLEEKRKKEEE--KRLREE 434
E+E ++ E R + E+E A + +EER RKE + + +L +R++++E +RL+++
Sbjct: 854 EEE-AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQ 912
Query: 435 EKRIKAEKAEI---TRFFQKPKTPQAPKTLAGSCGKFAPFEIKEHMVLAPRRRTAFHPDL 491
+++ + + ++ + + Q+ T S + E + L +R +L
Sbjct: 913 QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQ-QREL 971
Query: 492 CSQLDQLLQQQSGEFS 507
L Q QQQ + S
Sbjct: 972 MKALQQQQQQQQQKLS 987
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 77.4 bits (189), Expect = 6e-14
Identities = 60/204 (29%), Positives = 110/204 (53%), Gaps = 12/204 (5%)
Query: 243 QDILAVRPPQIKSLPATPQGKNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAP 302
Q LA+ Q ++L +N+ P S P+ S+ +S + EG
Sbjct: 653 QQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPTASQPTVW--EGGSVW 710
Query: 303 PKQHSSTSPFPTSTPLRRITK-KFVKGSTEKNK--LRLQRDQERLGKQLKLRAEREEKEK 359
+T+P P L+++ K K K E+ + +R +R++E +Q +LR ++EE
Sbjct: 711 DLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEI-- 768
Query: 360 LKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKL 419
+R +EE +K++EEE+ + K+ R + E+E A +++ +EE R++++EAL +L
Sbjct: 769 ----LRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALR-RL 823
Query: 420 EEKRKKEEEKRLREEEKRIKAEKA 443
EE+R++EEE+R +EE R + E+A
Sbjct: 824 EERRREEEERRKQEELLRKQEEEA 847
Score = 60.8 bits (146), Expect = 6e-09
Identities = 42/134 (31%), Positives = 79/134 (58%), Gaps = 15/134 (11%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEA------KRAKEEAKKKKEEEKELKEK 384
++ LR QR+QE + LR +REE+E+ ++E +R +EE +++K+EE K++
Sbjct: 790 QEEALRRQREQE-----IALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE 844
Query: 385 ERREKREKDEKEKAEKQRLKEERRKERQEA--LEAKLEEKRKKEEEKRLREEEKRIKAEK 442
E K ++E+E ++RL+E R + +EA L + EE+++KE E + ++E R + ++
Sbjct: 845 EEAAKWAREEEE--AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQ 902
Query: 443 AEITRFFQKPKTPQ 456
E R Q+ + Q
Sbjct: 903 QEALRRLQQQQQQQ 916
Score = 58.5 bits (140), Expect = 3e-08
Identities = 41/139 (29%), Positives = 77/139 (55%), Gaps = 17/139 (12%)
Query: 318 LRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKE------KLKEEAKRAKEEA 371
LRR ++ ++ E+ + R R++E L ++ + A R ++E + +EE +R ++E
Sbjct: 761 LRRQQEEILRRQQEEERKR--REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 818
Query: 372 KKKKEEEKELKEKERREKRE---KDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEE 428
++ EE+ +E+ERR++ E K E+E A+ R +EE ++ +E R +EE
Sbjct: 819 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEE------NRLRMEEEA 872
Query: 429 KRLREEEKRIKAEKAEITR 447
RLR EE+ K ++ E+ R
Sbjct: 873 ARLRHEEEERKRKELEVQR 891
Score = 53.5 bits (127), Expect = 9e-07
Identities = 48/196 (24%), Positives = 97/196 (49%), Gaps = 8/196 (4%)
Query: 318 LRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEE 377
LRR ++ + ++ + Q+ +E L + + R E EE+ K +E ++ +EEA K E
Sbjct: 794 LRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWARE 853
Query: 378 EKELKEKERREKREKDEKEKAEKQRLKEER-RKERQEALEAKLEEKRKKEEE--KRLREE 434
E+E ++ E R + E+E A + +EER RKE + + +L +R++++E +RL+++
Sbjct: 854 EEE-AQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQ 912
Query: 435 EKRIKAEKAEI---TRFFQKPKTPQAPKTLAGSCGKFAPFEIKEHMVLAPRRRTAFHPDL 491
+++ + + ++ + + Q+ T S + E + L +R +L
Sbjct: 913 QQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQ-QREL 971
Query: 492 CSQLDQLLQQQSGEFS 507
L Q QQQ + S
Sbjct: 972 MKALQQQQQQQQQKLS 987
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 77.0 bits (188), Expect = 8e-14
Identities = 50/137 (36%), Positives = 84/137 (61%), Gaps = 19/137 (13%)
Query: 327 KGSTEKNKLRLQRDQERLGKQLKLR--AEREEKEKLKEEAKRAKEEAKKKK----EEEKE 380
K E+ + RL+R+QE LK ER E+E+ K++ KR +EE ++++ EEE+
Sbjct: 437 KHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEER 496
Query: 381 LKEKERREKREKDEKEKAEKQRLKEERRKER-------QEALEAKLEEKR----KKEEEK 429
+++ERRE++ + E+E+ +QRLK + +ER ++ L + EE+R K+EEEK
Sbjct: 497 REQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEK 556
Query: 430 RLREE--EKRIKAEKAE 444
RL +E E+R+K E+ E
Sbjct: 557 RLEQERREQRLKREQEE 573
Score = 75.5 bits (184), Expect = 2e-13
Identities = 36/124 (29%), Positives = 84/124 (67%), Gaps = 3/124 (2%)
Query: 316 TPLRRITKKFVKGSTEKNKLRLQRDQERLGK--QLKLRAEREEKEKLKEEAKRAKEEAKK 373
T LR+ +K + ++ + LQ ++E+L K + +LR ER+E+E+ ++ +R ++ +K
Sbjct: 251 TVLRKEEEKLQEEEPQRQR-ELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRK 309
Query: 374 KKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLRE 433
++EE +E +E+ R ++ ++++E+ +Q+L+ E+ + R++ L + EE+R++++ +R +E
Sbjct: 310 QEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQE 369
Query: 434 EEKR 437
EE+R
Sbjct: 370 EERR 373
Score = 71.2 bits (173), Expect = 4e-12
Identities = 46/138 (33%), Positives = 81/138 (58%), Gaps = 11/138 (7%)
Query: 309 TSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAK 368
T FP LRR ++ ++ + K R ++ Q+R +Q ++ E EEKE K E K
Sbjct: 201 TEEFPDEEQLRR--RELLE---LRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRK 255
Query: 369 EEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEE--KRKKE 426
EE K ++EE +++R + E+++ K E+Q L+ ER++E Q+ + E+ +RK+E
Sbjct: 256 EEEKLQEEE----PQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQE 311
Query: 427 EEKRLREEEKRIKAEKAE 444
EE+R ++EE+R + E+ E
Sbjct: 312 EERREQQEERREQQERRE 329
Score = 70.9 bits (172), Expect = 6e-12
Identities = 34/110 (30%), Positives = 74/110 (67%), Gaps = 3/110 (2%)
Query: 341 QERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKER---REKREKDEKEK 397
QE+L K+ +L E EE+ + +E KR ++E +++ EE++L+++E RE+REK +++
Sbjct: 896 QEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQE 955
Query: 398 AEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITR 447
E+Q K+++ ++++E L + EKR+++E ++ EE+ ++ E+ ++ R
Sbjct: 956 RERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLR 1005
Score = 70.1 bits (170), Expect = 9e-12
Identities = 45/125 (36%), Positives = 76/125 (60%), Gaps = 12/125 (9%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERRE-- 388
E+ + RL+R+QE QL R E +++LK E + E+ + K+EE + L+++ERRE
Sbjct: 561 ERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQ-RLKREEVERLEQEERREQR 619
Query: 389 -KREKDEKEKAEKQRLKEERRKERQEALEAKLEEKR-----KKEEEKRLREEEKRIKAEK 442
KRE+ E+E+ ++ EE+ + RQ+ L + +E+R ++EEE+RL E+R+K E
Sbjct: 620 LKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERL---EQRLKREH 676
Query: 443 AEITR 447
E R
Sbjct: 677 EEERR 681
Score = 70.1 bits (170), Expect = 9e-12
Identities = 39/117 (33%), Positives = 74/117 (63%), Gaps = 7/117 (5%)
Query: 332 KNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEE-EKELKEKERREKR 390
K+K Q++++ LG++ + R +E ++K +EE + +EE + +EE EK +++ R+ R
Sbjct: 962 KDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYR 1021
Query: 391 EKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITR 447
+KDE ++ E+Q L+EER K R + E +R+ EE+ L++EE+++ E+ E R
Sbjct: 1022 KKDELQQEEEQLLREEREKRRLQ------ERERQYREEEELQQEEEQLLGEERETRR 1072
Score = 70.1 bits (170), Expect = 9e-12
Identities = 38/110 (34%), Positives = 73/110 (66%), Gaps = 3/110 (2%)
Query: 338 QRDQERLGKQLKLRAERE-EKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKE 396
Q +++ LG++ + R +E E++ KEE + +EE ++E EK +++ R+ RE++E +
Sbjct: 1058 QEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQ 1117
Query: 397 KAEKQRLKEERRKERQEALEAKL--EEKRKKEEEKRLREEEKRIKAEKAE 444
+ E+Q L+EER K R++ LE + EE+ ++EEE+ LREE ++ + ++ E
Sbjct: 1118 QEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELE 1167
Score = 68.9 bits (167), Expect = 2e-11
Identities = 53/155 (34%), Positives = 98/155 (63%), Gaps = 29/155 (18%)
Query: 331 EKNKLRLQRDQE--RLGKQLKLRAE--REEKEKLKEEAKRAKEEAK----KKKEEEKELK 382
E+ K +L+RDQE R + LKL E RE++E+ +++ +R +EE + K++EEE+ L+
Sbjct: 470 ERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQ 529
Query: 383 EKERRE---KREKDEK-----EKAEKQRLKEERRKERQEALEAKLEEKR----KKEEEKR 430
++ R E +RE++E+ ++ E++RL++ERR++R L+ + EE+R K+EEE+R
Sbjct: 530 QRLRSEQQLRREQEERREQLLKREEEKRLEQERREQR---LKREQEERRDQLLKREEERR 586
Query: 431 ----LREEEKRI--KAEKAEITRFFQKPKTPQAPK 459
RE+E+R+ + ++ E+ R Q+ + Q K
Sbjct: 587 QQRLKREQEERLEQRLKREEVERLEQEERREQRLK 621
Score = 68.6 bits (166), Expect = 3e-11
Identities = 45/138 (32%), Positives = 84/138 (60%), Gaps = 12/138 (8%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEK--EKLKEEAKRAKEEAKK-----KKEEEKELKE 383
E+ + +L+R+QE +Q R E EE+ ++L+ E + +E+ ++ K+EEEK L++
Sbjct: 501 ERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQ 560
Query: 384 --KERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEK---RI 438
+E+R KRE++E+ +R +E R++ + E +LE++ K+EE +RL +EE+ R+
Sbjct: 561 ERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRL 620
Query: 439 KAEKAEITRFFQKPKTPQ 456
K E+ E R Q K+ +
Sbjct: 621 KREEPEEERRQQLLKSEE 638
Score = 68.6 bits (166), Expect = 3e-11
Identities = 42/125 (33%), Positives = 80/125 (64%), Gaps = 11/125 (8%)
Query: 324 KFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKE--- 380
+ +K E+ + RL+R+QE ++L+ R +REE E+L++E +R + +++ EEE+
Sbjct: 577 QLLKREEERRQQRLKREQE---ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQL 633
Query: 381 LKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKR---LREEEKR 437
LK +E+ E+R++ + + +++R + +R+E +E LE +L KR+ EEE+R L EEE+
Sbjct: 634 LKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRL--KREHEEERREQELAEEEQE 691
Query: 438 IKAEK 442
E+
Sbjct: 692 QARER 696
Score = 68.2 bits (165), Expect = 4e-11
Identities = 42/142 (29%), Positives = 87/142 (61%), Gaps = 5/142 (3%)
Query: 320 RITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLK-EEAKRAKEEAKKKKEEE 378
R ++ + E+ L+R++ER ++LK E +++LK EE +R ++E ++++ +
Sbjct: 562 RREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLK 621
Query: 379 KELKEKERREKREK-DEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKR 437
+E E+ERR++ K +E+E+ +Q+L+ E+++ R++ L+ + EE+R ++ KR EEE+R
Sbjct: 622 REEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERR 681
Query: 438 ---IKAEKAEITRFFQKPKTPQ 456
+ E+ E R K + P+
Sbjct: 682 EQELAEEEQEQARERIKSRIPK 703
Score = 68.2 bits (165), Expect = 4e-11
Identities = 41/116 (35%), Positives = 75/116 (64%), Gaps = 5/116 (4%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKER---R 387
E+ K R Q + + K KL+ ++EE+ +E KR ++E +KK EE+EL+++E R
Sbjct: 947 EREKRRRQERERQYRKDKKLQ-QKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLR 1005
Query: 388 EKREKDEKEKAEKQ-RLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEK 442
E+REK +++ E+Q R K+E ++E ++ L + E++R +E E++ REEE+ + E+
Sbjct: 1006 EEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEE 1061
Score = 67.4 bits (163), Expect = 6e-11
Identities = 37/110 (33%), Positives = 74/110 (67%), Gaps = 4/110 (3%)
Query: 337 LQRDQERLGKQLKLRAEREEKEKL--KEEAKRAKEEAKKKKEEEKELKEKERREKREKDE 394
LQ+++E+L ++ + R+E+E+ +EE + +EE ++E EK +++ R+ RE++E
Sbjct: 1086 LQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEE 1145
Query: 395 KEKAEKQRLKEERRKERQEALEAKL--EEKRKKEEEKRLREEEKRIKAEK 442
++ E+Q L+EE K R++ LE + EE+ ++EEE+ LREE+++ + E+
Sbjct: 1146 VQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER 1195
Score = 67.0 bits (162), Expect = 8e-11
Identities = 93/430 (21%), Positives = 194/430 (45%), Gaps = 53/430 (12%)
Query: 336 RLQRDQERLGKQLKLRAE--REEKEKLKEEA-KRAKEEAKKKKEEEKELKEKER---REK 389
R R ++ L +Q + E +EE++ L+EE KR ++E +++ EE+EL+++E RE+
Sbjct: 1068 RETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREE 1127
Query: 390 REKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITRFF 449
REK +++ E+Q +EE ++ +E L + EKR+++E +R EE+ ++ E+ ++ R
Sbjct: 1128 REKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE 1187
Query: 450 QKPKTPQAPKTLAGSCGKFAPFEIKEHMVLAPRRRTAFHPDLCSQLDQLLQQQSGEFSFL 509
Q+ + + + + +E L ++R + D + D Q + + + +
Sbjct: 1188 QEKRRQERER------------QYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAV 1235
Query: 510 KD----LKGRQPLRSGPTHVSTRNADIFNSDV--VIVERGKGDGVPERRKFGRMKLLQFC 563
+D KGR+ + S D+ ++ E+ + D ERR++ Q
Sbjct: 1236 RDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRW------QQR 1289
Query: 564 ENHRPAYWGTWNKKTALIRARDPWAQDTKLL--------------DYEVDSDEEWEEEEP 609
+ H P ++ + RD +Q+ K L D + +E+ +E
Sbjct: 1290 DRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQERE 1349
Query: 610 GESLSHSEGDDDDDMGEDEDEDDGFFVPHGYLSEDEGVTEECADPENHKVRQKLKAKEWD 669
+ L E D E ++ G +L E++ + + + + K Q+L+ +E +
Sbjct: 1350 EQPLRRQERDRKFREEELRHQEQG----RKFLEEEQRLRRQERERKFLKEEQQLRCQERE 1405
Query: 670 EFLAKGKRFRVLQPVKIGCVWAADRDCAGDDLKV-LQQFAACFLETLPAQEEQTPKASKR 728
+ L + + + + + DR ++ +V Q+ FLE +E+Q + R
Sbjct: 1406 QQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLE----EEQQLRQERHR 1461
Query: 729 ERRDEQILAQ 738
+ R+E+ L Q
Sbjct: 1462 KFREEEQLLQ 1471
Score = 66.6 bits (161), Expect = 1e-10
Identities = 39/122 (31%), Positives = 76/122 (62%), Gaps = 14/122 (11%)
Query: 332 KNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKK---------KKEEEKELK 382
+ + +L+R+Q+ +Q R + EE+ + K E +R ++ K+ K+EEE E
Sbjct: 408 RREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERH 467
Query: 383 EKERREKREKDEKEKAEKQR---LKEERRKERQEALEAKLEEKRKKEEEKRLR--EEEKR 437
E+ERR+++ K ++E+ ++R L+EE R+E+QE E +L ++++ E+RL+ EEE+R
Sbjct: 468 EQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEER 527
Query: 438 IK 439
++
Sbjct: 528 LQ 529
Score = 66.2 bits (160), Expect = 1e-10
Identities = 38/132 (28%), Positives = 84/132 (63%), Gaps = 5/132 (3%)
Query: 336 RLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREK--REKD 393
+LQ+++E+L ++ + + R+E+E+ + K+ +++ ++ EE E + ++ REK RE++
Sbjct: 935 QLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEE 994
Query: 394 EKEKAEKQRLKEERRKERQEALEAKLEEK--RKKEEEKRLREEEKRIKAEKAEITRFFQK 451
E ++ E+Q L+EER K R++ E + +K ++EEE+ LREE ++ + ++ E ++ ++
Sbjct: 995 ELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERE-RQYREE 1053
Query: 452 PKTPQAPKTLAG 463
+ Q + L G
Sbjct: 1054 EELQQEEEQLLG 1065
Score = 66.2 bits (160), Expect = 1e-10
Identities = 36/112 (32%), Positives = 74/112 (66%), Gaps = 5/112 (4%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEK----EKLKEEAKRAKEEAKKKKEEEK-ELKEKE 385
E+ +LR +R++++L Q R REE+ E+ +++ + + + K + EEE+ +L+E+E
Sbjct: 1775 EEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQE 1834
Query: 386 RREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKR 437
+R ++E+D + +AE+Q +E+ + ++ L + E+KR++E E++LREE R
Sbjct: 1835 QRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIR 1886
Score = 65.5 bits (158), Expect = 2e-10
Identities = 33/110 (30%), Positives = 78/110 (70%), Gaps = 7/110 (6%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKR 390
E+ +LR +R +E +Q + R RE++ + K+E +R +++ ++++++E+ +++ERRE++
Sbjct: 282 ERQELRRERQEE---EQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQ 338
Query: 391 EKDEKEKAEKQRLKEERRKERQEA-LEAKLEEKRKKEE---EKRLREEEK 436
+ E+E+ +Q+L+ E+ +ER+E L + EE+R++++ E++LR E++
Sbjct: 339 LRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQ 388
Score = 65.1 bits (157), Expect = 3e-10
Identities = 43/137 (31%), Positives = 86/137 (62%), Gaps = 23/137 (16%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKE---KLKEEAKRAKEEAKK---KKEEEKELKEK 384
E+ + R ++ E+ ++ +L+ E+EE+ K +EE +R ++E +K K+++E+E +E+
Sbjct: 428 EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Query: 385 ----ERREKREKDEKEKAEKQRLKEERRKER------QEALEAKL---EEKRKKEEEKR- 430
E E+RE+ E+ + + +R +EERR++R +E L+ +L ++ R+++EE+R
Sbjct: 488 WLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERRE 547
Query: 431 ---LREEEKRIKAEKAE 444
REEEKR++ E+ E
Sbjct: 548 QLLKREEEKRLEQERRE 564
Score = 65.1 bits (157), Expect = 3e-10
Identities = 37/109 (33%), Positives = 74/109 (67%), Gaps = 6/109 (5%)
Query: 340 DQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAE 399
+QER ++LK E + LK E +R ++ + K+E+E+ L+++ +RE+ E+ E+E+
Sbjct: 559 EQERREQRLKREQEERRDQLLKREEERRQQ--RLKREQEERLEQRLKREEVERLEQEERR 616
Query: 400 KQRLKEERRKE--RQEALEAKLEEKRKKEEEKRLREE--EKRIKAEKAE 444
+QRLK E +E RQ+ L+++ +E+R++++ +R ++E E+R+K E+ E
Sbjct: 617 EQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEE 665
Score = 65.1 bits (157), Expect = 3e-10
Identities = 40/112 (35%), Positives = 77/112 (68%), Gaps = 7/112 (6%)
Query: 337 LQRDQERLGKQLKLRAEREEKEKL---KEEAKRAKEEAKKKKEEEKELKEKERREKREKD 393
LQ+++E+L ++ + + R+E E+ K+E ++ +E+ +++ E++ L+E+E R+ RE++
Sbjct: 996 LQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERE-RQYREEE 1054
Query: 394 EKEKAEKQRLKEERRKERQEALEA--KLEEKRKKEEEKRLREE-EKRIKAEK 442
E ++ E+Q L EER R++ LE + EE+ ++EEE+ LREE EKR + E+
Sbjct: 1055 ELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQER 1106
Score = 64.7 bits (156), Expect = 4e-10
Identities = 45/192 (23%), Positives = 98/192 (51%), Gaps = 4/192 (2%)
Query: 332 KNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKRE 391
+ +LR ++++ER +QL+ E E +E+ ++ + E + ++E++ +++ RRE++
Sbjct: 348 EQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 407
Query: 392 KDEKEKAEKQRLKEE---RRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITRF 448
+ E++ +Q+L+ E RR++ +E E K E++R+++ KR +EE + + E R
Sbjct: 408 RREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERH 467
Query: 449 FQKPKTPQAPKTLAGS-CGKFAPFEIKEHMVLAPRRRTAFHPDLCSQLDQLLQQQSGEFS 507
Q+ + Q + ++ E +E RR + + +Q L++Q E
Sbjct: 468 EQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEER 527
Query: 508 FLKDLKGRQPLR 519
+ L+ Q LR
Sbjct: 528 LQQRLRSEQQLR 539
Score = 63.5 bits (153), Expect = 9e-10
Identities = 38/121 (31%), Positives = 76/121 (62%), Gaps = 6/121 (4%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEA-KRAKEEAKKKKEEEKELKEKERR-- 387
E+ K R Q + + K+ +L ++EE++ L+EE KR +E +++ EE+EL+++E +
Sbjct: 1007 EREKRRRQEWERQYRKKDEL--QQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLL 1064
Query: 388 -EKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEIT 446
E+RE +++ E+Q KEE ++ +E L + EKR+++E +R EE+ ++ E+ ++
Sbjct: 1065 GEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLL 1124
Query: 447 R 447
R
Sbjct: 1125 R 1125
Score = 63.5 bits (153), Expect = 9e-10
Identities = 42/140 (30%), Positives = 81/140 (57%), Gaps = 13/140 (9%)
Query: 319 RRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAK--------RAKEE 370
R+ KK E+ LR +R++ RL Q + R REE+E +EE + R ++E
Sbjct: 1018 RQYRKKDELQQEEEQLLREEREKRRL--QERERQYREEEELQQEEEQLLGEERETRRRQE 1075
Query: 371 AKKKKEEEKELKEKER---REKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEE 427
+++ +E+EL+++E RE+ EK +++ E+Q +EE ++ +E L + EKR+++E
Sbjct: 1076 LERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE 1135
Query: 428 EKRLREEEKRIKAEKAEITR 447
+R EE+ ++ E+ ++ R
Sbjct: 1136 LERQYREEEEVQQEEEQLLR 1155
Score = 63.2 bits (152), Expect = 1e-09
Identities = 33/109 (30%), Positives = 71/109 (65%), Gaps = 3/109 (2%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKER---R 387
E+ + R ++++ER ++ + + EE+ +E KR ++E +++ EE+E++++E R
Sbjct: 1096 EEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLR 1155
Query: 388 EKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEK 436
E+ EK +++ E+Q +EE ++ +E L + +EKR++E E++ REEE+
Sbjct: 1156 EEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEE 1204
Score = 62.8 bits (151), Expect = 1e-09
Identities = 35/122 (28%), Positives = 78/122 (63%), Gaps = 8/122 (6%)
Query: 334 KLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREK--RE 391
K R Q ++ER ++ L A+ +E+L++E + +EE ++ + EE+E + ++ +E+ RE
Sbjct: 873 KWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYRE 932
Query: 392 KDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITRFFQK 451
+++ ++ E+Q L+EER K R++ E +R+ ++K+L+++E+++ E+ E R ++
Sbjct: 933 EEQLQQEEEQLLREEREKRRRQ------ERERQYRKDKKLQQKEEQLLGEEPEKRRRQER 986
Query: 452 PK 453
K
Sbjct: 987 EK 988
Score = 62.4 bits (150), Expect = 2e-09
Identities = 46/142 (32%), Positives = 83/142 (58%), Gaps = 16/142 (11%)
Query: 318 LRRITKKFVKGSTEKNKLRLQRDQ-----ERLGKQLKLRAE---REEKEKLKEEAKRAKE 369
LRR ++ + + + +L+R+Q ++L ++ +LR E R E++ +E+ R ++
Sbjct: 364 LRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 423
Query: 370 EAKKKKEEEK--ELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEE 427
+ ++++EEE+ + E+ERRE+R K E+E+ + LK E ER E K + KR +EE
Sbjct: 424 QLRREQEEERHEQKHEQERREQRLKREQEE-RRDWLKREEETERHEQERRKQQLKRDQEE 482
Query: 428 EKR-----LREEEKRIKAEKAE 444
E+R L EEE+R + E+ E
Sbjct: 483 ERRERWLKLEEEERREQQERRE 504
Score = 62.0 bits (149), Expect = 3e-09
Identities = 31/113 (27%), Positives = 75/113 (66%), Gaps = 7/113 (6%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAE-----REEKEKLKEEAKRAKEEAKKKKEE--EKELKE 383
E+ + RL+R+Q+ KQ + R E RE++E+ +++ +R +++ ++++EE E++L+
Sbjct: 294 EQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRR 353
Query: 384 KERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEK 436
++ E+RE+ + + E++R +++ R+E+Q E +L +++ E++LR E++
Sbjct: 354 EQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 406
Score = 62.0 bits (149), Expect = 3e-09
Identities = 45/135 (33%), Positives = 81/135 (60%), Gaps = 18/135 (13%)
Query: 332 KNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKER----- 386
+ K LQ+++E+L LR ERE K +L+E ++ +EE + ++EEE+ L E+
Sbjct: 1021 RKKDELQQEEEQL-----LREERE-KRRLQERERQYREEEELQQEEEQLLGEERETRRRQ 1074
Query: 387 ---REKREKDEKEKAEKQRLKEERRKERQEALE--AKLEEKRKKEEEKRLREEEKRIKAE 441
R+ R+++E ++ E+Q L+EE K R++ E + EE+ ++EEE+ LREE R K
Sbjct: 1075 ELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREE--REKRR 1132
Query: 442 KAEITRFFQKPKTPQ 456
+ E+ R +++ + Q
Sbjct: 1133 RQELERQYREEEEVQ 1147
Score = 61.6 bits (148), Expect = 3e-09
Identities = 37/120 (30%), Positives = 78/120 (65%), Gaps = 5/120 (4%)
Query: 331 EKNKLRLQRDQ-ERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREK 389
++ + LQR++ E+ +Q + R REE++ +EE + +EE +K++ +E+E + ++ ++
Sbjct: 907 QEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKL 966
Query: 390 REKDEK---EKAEKQRLKEERRKER-QEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEI 445
++K+E+ E+ EK+R +E +K R +E L+ + E+ ++E EKR R+E +R +K E+
Sbjct: 967 QQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL 1026
Score = 60.8 bits (146), Expect = 6e-09
Identities = 41/125 (32%), Positives = 76/125 (60%), Gaps = 7/125 (5%)
Query: 323 KKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELK 382
K ++ K + LQ ++E L ++ + + R+E+E+ E ++ ++E ++ EE+E +
Sbjct: 892 KPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKR 951
Query: 383 ---EKERREKREKDEKEKAEKQRLKEERRKERQEALEAKL--EEKRKKEEEKRLREE-EK 436
E+ER+ +++K ++K E+Q L EE K R++ E K EE+ ++EEE+ LREE EK
Sbjct: 952 RRQERERQYRKDKKLQQK-EEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREK 1010
Query: 437 RIKAE 441
R + E
Sbjct: 1011 RRRQE 1015
Score = 60.8 bits (146), Expect = 6e-09
Identities = 34/130 (26%), Positives = 86/130 (66%), Gaps = 12/130 (9%)
Query: 323 KKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKK-KEEEKEL 381
+KF++ E+ +LR Q +++R ++ +LR++ E++ L+EE + +++ ++K +EE++L
Sbjct: 1485 RKFLE---EEQQLRRQ-ERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQL 1540
Query: 382 KEKERREKREKDEKEK-AEKQRLKEER------RKERQEALEAKLEEKRKKEEEKRLREE 434
+ +ER ++R +D K E+++L++ER R+ER + ++ R++E+E++ E+
Sbjct: 1541 RRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMED 1600
Query: 435 EKRIKAEKAE 444
E++++ ++ +
Sbjct: 1601 EQQLRRQEGQ 1610
Score = 60.1 bits (144), Expect = 1e-08
Identities = 34/119 (28%), Positives = 75/119 (63%), Gaps = 11/119 (9%)
Query: 337 LQRDQERLGKQLKLRAEREEKEKLKEEAKRAK----------EEAKKKKEEEKELKEKER 386
LQ DQER Q + R +++ + +L+EE KR + E+ +K+++ +E +E+ +
Sbjct: 856 LQEDQERRRSQ-EQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQ 914
Query: 387 REKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEI 445
RE+REK +++ E+Q +EE+ ++ +E L + EKR+++E +R ++K+++ ++ ++
Sbjct: 915 REEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQL 973
Score = 60.1 bits (144), Expect = 1e-08
Identities = 35/132 (26%), Positives = 76/132 (57%), Gaps = 2/132 (1%)
Query: 320 RITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEK 379
R ++ ++ E+ R +RD++ ++ +LR + E++ L+EE + ++E ++K EE+
Sbjct: 1670 REEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEE 1729
Query: 380 ELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIK 439
+L+++ +E+ + E+ + K +E+ R ER+E + E RK EE++LR+E + +
Sbjct: 1730 QLRQETEQEQLRRQERYR--KILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQ 1787
Query: 440 AEKAEITRFFQK 451
E R F++
Sbjct: 1788 LRSQESDRKFRE 1799
Score = 59.7 bits (143), Expect = 1e-08
Identities = 35/132 (26%), Positives = 83/132 (62%), Gaps = 6/132 (4%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEK--EKLKEEAKRAKEEAKKKKEEEKELKEKE-RR 387
E+ + + +R+Q+ ++ +LR E+EE+ ++L+ E + + E + ++E+E+E +E++ RR
Sbjct: 320 ERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRR 379
Query: 388 EKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKE---EEKRLREEEKRIKAEKAE 444
E++ + E++ +Q+L+ E++ R++ L + + +R+++ E++ RE+E+ +K E
Sbjct: 380 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHE 439
Query: 445 ITRFFQKPKTPQ 456
R Q+ K Q
Sbjct: 440 QERREQRLKREQ 451
Score = 58.9 bits (141), Expect = 2e-08
Identities = 33/122 (27%), Positives = 78/122 (63%), Gaps = 9/122 (7%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEK---EKLKEEAKRAKEEAKKKKEEEKELKEKERR 387
E+ + +L+R+QE +Q +LR E+EE+ ++L+ E + + E + ++E++ +++ RR
Sbjct: 333 ERREQQLRREQEERREQ-QLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRR 391
Query: 388 EKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLRE-----EEKRIKAEK 442
E++ + E++ +Q+L+ E++ R++ L + + +R++EEE+ ++ E+R+K E+
Sbjct: 392 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQ 451
Query: 443 AE 444
E
Sbjct: 452 EE 453
Score = 58.9 bits (141), Expect = 2e-08
Identities = 32/138 (23%), Positives = 84/138 (60%), Gaps = 13/138 (9%)
Query: 323 KKFVKGSTEKNKLRLQR-----------DQERLGKQLKLRAEREEKEKLKEEAKRAKEEA 371
++F+ EK + R QR ++E+L ++ + + +EE++ L+E+ +R + +
Sbjct: 808 QRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQE 867
Query: 372 KKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERR--KERQEALEAKLEEKRKKEEEK 429
+++ ++ + E+ER+ +R + A +++L++E++ +E +E L+ + EKR+++E++
Sbjct: 868 QRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQE 927
Query: 430 RLREEEKRIKAEKAEITR 447
R EE++++ E+ ++ R
Sbjct: 928 RQYREEEQLQQEEEQLLR 945
Score = 58.5 bits (140), Expect = 3e-08
Identities = 41/151 (27%), Positives = 87/151 (57%), Gaps = 12/151 (7%)
Query: 323 KKFVKGSTE------KNKLRLQRDQE-RLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKK 375
+KF+K + + +LR RD++ R +Q R ER+ K + +E+ R +E +K
Sbjct: 1390 RKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFL 1449
Query: 376 EEEKELKEKERREKREKDE--KEKAEKQRLKEERRK---ERQEALEAKLEEKRKKEEEKR 430
EEE++L+++ R+ RE+++ +E+ E+Q ++ER + E ++ L + +++ +E+E R
Sbjct: 1450 EEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELR 1509
Query: 431 LREEEKRIKAEKAEITRFFQKPKTPQAPKTL 461
+E E++ E+ ++ R ++ K Q + L
Sbjct: 1510 SQEPERKFLEEEQQLHRQQRQRKFLQEEQQL 1540
Score = 57.8 bits (138), Expect = 5e-08
Identities = 35/119 (29%), Positives = 69/119 (57%), Gaps = 4/119 (3%)
Query: 330 TEKNKLRLQRDQER----LGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKE 385
+EK + QRD++R L +Q + EREE+ +E+ + K ++ +E++L+ +E
Sbjct: 155 SEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRE 214
Query: 386 RREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAE 444
E R K +EK +++R +++R + +E E + E ++EE++L+EEE + + E E
Sbjct: 215 LLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQE 273
Score = 57.8 bits (138), Expect = 5e-08
Identities = 39/160 (24%), Positives = 87/160 (54%), Gaps = 45/160 (28%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERRE-- 388
E+ +LR +R++++L +Q ER+ K +L+E+ R +E+ +K E+E++L+ +E ++
Sbjct: 1559 EEEQLRQEREEQQLSRQ-----ERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQL 1613
Query: 389 KREKDEKEKAEKQRLKEE---------------------RRKERQEAL------------ 415
++E+D K + ++Q L+E RR+ER++ L
Sbjct: 1614 RQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEE 1673
Query: 416 ----EAKLEEKRKKEEEKRLREEEKRIKAEKAEITRFFQK 451
E + ++ R++E +++ REEE++++ ++ E +F Q+
Sbjct: 1674 QLLQEGEEQQLRRQERDRKFREEEQQLRRQERE-RKFLQE 1712
Score = 57.8 bits (138), Expect = 5e-08
Identities = 37/128 (28%), Positives = 79/128 (61%), Gaps = 7/128 (5%)
Query: 323 KKFVKGSTEKNKLRLQRDQERL--GKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKE 380
+KF++ E+ +LR Q +++L + K R E + ++ +E+ R +E +K +EEE++
Sbjct: 1643 RKFLE---EEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQ 1699
Query: 381 LKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEK-RIK 439
L+ +ER E++ E+++ +Q L+ + R+E Q E + E+ R++E +++ EEE+ R +
Sbjct: 1700 LRRQER-ERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPE 1758
Query: 440 AEKAEITR 447
E+ ++ R
Sbjct: 1759 REEQQLRR 1766
Score = 56.6 bits (135), Expect = 1e-07
Identities = 45/193 (23%), Positives = 96/193 (49%), Gaps = 16/193 (8%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEE--------KELK 382
+K + L + E+ +Q + + REE+E +EE + +EE +K++ +E EL+
Sbjct: 968 QKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQ 1027
Query: 383 EKERREKREKDEK----EKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRI 438
++E + RE+ EK E+ + R +EE ++E ++ L + E +R++E E++ R+EE+
Sbjct: 1028 QEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQ 1087
Query: 439 KAEKAEITRFFQKPKTPQAPKTLAGSCGKFAPFEIKEHMVLAPRRRTAFHPDLCSQLDQL 498
+ E+ + +K + + + C + + +E +L R +L Q +
Sbjct: 1088 QEEEQLLREEPEKRRRQERER----QCREEEELQQEEEQLLREEREKRRRQELERQYREE 1143
Query: 499 LQQQSGEFSFLKD 511
+ Q E L++
Sbjct: 1144 EEVQQEEEQLLRE 1156
Score = 56.6 bits (135), Expect = 1e-07
Identities = 37/132 (28%), Positives = 80/132 (60%), Gaps = 14/132 (10%)
Query: 323 KKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRA---KEEAKKKKEEEK 379
+KF++ ++ +LR Q Q++L +Q + R RE+++ L+E ++ +E +K EEE
Sbjct: 1595 RKFME---DEQQLRRQEGQQQL-RQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEP 1650
Query: 380 ELKEKERRE--KREKDEKEKAEKQRLKEE-----RRKERQEALEAKLEEKRKKEEEKRLR 432
+L+ +ER + + ++D K + E+Q L+E RR+ER + ++ R++E E++
Sbjct: 1651 QLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFL 1710
Query: 433 EEEKRIKAEKAE 444
+EE++++ ++ E
Sbjct: 1711 QEEQQLRRQELE 1722
Score = 56.6 bits (135), Expect = 1e-07
Identities = 32/115 (27%), Positives = 69/115 (60%), Gaps = 3/115 (2%)
Query: 331 EKNKLRLQRDQERLGKQLKLRA--EREEKEKLKEEAKRAKEEAKKKKEEEKELK-EKERR 387
E+ +LR + +QE+L +Q + R E E+ +EE + ++E +K EE++L+ E+E +
Sbjct: 1727 EEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQ 1786
Query: 388 EKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEK 442
+ R ++ K ++ + R+E+Q + + + R +EE+ +L E+E+R++ E+
Sbjct: 1787 QLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQER 1841
Score = 56.2 bits (134), Expect = 1e-07
Identities = 37/134 (27%), Positives = 74/134 (55%), Gaps = 24/134 (17%)
Query: 336 RLQRDQ----ERLGKQLKLRAEREEKEKLK----EEAKRAKEEAKKKKEEEKELKEKERR 387
R QR+Q E K+ + R RE +++L+ EE + +E A++ +EEE L+E + R
Sbjct: 803 RQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQER 862
Query: 388 EKREKDEKEKAEKQRLKEERRKER----------------QEALEAKLEEKRKKEEEKRL 431
+ ++ +++ + +L+EER++ R Q+ L+ + EE +++E EKR
Sbjct: 863 RRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRR 922
Query: 432 REEEKRIKAEKAEI 445
R+E++R E+ ++
Sbjct: 923 RQEQERQYREEEQL 936
Score = 56.2 bits (134), Expect = 1e-07
Identities = 46/164 (28%), Positives = 83/164 (50%), Gaps = 28/164 (17%)
Query: 312 FPTSTPLRRITKKFVK-----GSTEKNKLRLQRDQERLGKQL--------KLRAEREEK- 357
FP L R +K K EK LR +R+++R ++ +L EREE+
Sbjct: 1293 FPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQP 1352
Query: 358 -------EKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKE---KAEKQRLKEER 407
K +EE R +E+ +K EEE+ L+ +ER K K+E++ + +Q+L+++R
Sbjct: 1353 LRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDR 1412
Query: 408 ----RKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITR 447
R+E Q+ + + K ++EE++ R+E +R E+ + R
Sbjct: 1413 DRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLR 1456
Score = 56.2 bits (134), Expect = 1e-07
Identities = 34/145 (23%), Positives = 88/145 (60%), Gaps = 12/145 (8%)
Query: 323 KKFVKGSTEKNKLRLQ-RDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKEL 381
+KF++ E+ +LR Q R+++ L ++ +LR + E++ ++ ++ +EE ++ +E++
Sbjct: 1374 RKFLE---EEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDR 1430
Query: 382 KEKERREKREKDEKEKA---EKQRLKEER----RKERQEALEAKLEEKRKKEEEKRLREE 434
K +E ++ + E+E+ E+Q+L++ER R+E Q E + ++ ++E +++ EE
Sbjct: 1431 KFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEE 1490
Query: 435 EKRIKAEKAEITRFFQKPKTPQAPK 459
E++++ ++ + +F ++ Q P+
Sbjct: 1491 EQQLRRQERD-RKFREQELRSQEPE 1514
Score = 55.8 bits (133), Expect = 2e-07
Identities = 36/117 (30%), Positives = 71/117 (60%), Gaps = 12/117 (10%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKR 390
E ++LR ++ Q+ L L + ER+ +++ + +R + ++++ E +E KE +RR+++
Sbjct: 1254 EDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRK 1313
Query: 391 EKDEK-----EKAEKQRLKEERRKERQEALEAKLEEK-----RKKEEEKRLREEEKR 437
++EK E+ EK+R +E RK R+E E L+E+ R++E +++ REEE R
Sbjct: 1314 SQEEKQLLREEREEKRRRQETDRKFREE--EQLLQEREEQPLRRQERDRKFREEELR 1368
Score = 54.7 bits (130), Expect = 4e-07
Identities = 29/129 (22%), Positives = 77/129 (59%), Gaps = 2/129 (1%)
Query: 319 RRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEE 378
+R+ ++ + + L+ + +ER +QL+ + +++LK E + + E + K+E E
Sbjct: 618 QRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHE 677
Query: 379 KELKEKERREKREKDEKEKAEKQRLKEERRKERQ-EALEAKLEEK-RKKEEEKRLREEEK 436
+E +E+E E+ ++ +E+ + + K + + E + +A ++K+ + RK+E ++R +E+E+
Sbjct: 678 EERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEE 737
Query: 437 RIKAEKAEI 445
+ + ++E+
Sbjct: 738 KRRRRESEL 746
Score = 54.7 bits (130), Expect = 4e-07
Identities = 44/196 (22%), Positives = 105/196 (53%), Gaps = 15/196 (7%)
Query: 320 RITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEK 379
R ++ ++ E+ R +RD++ L ++ +LR + ++ K +E+ R++E +K EEE+
Sbjct: 1464 REEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDR-KFREQELRSQEPERKFLEEEQ 1522
Query: 380 ELKEKERREKREKDEKEKAEKQRLKEERR-KERQEALEAKLEEKRKKEEEKRLREEEKRI 438
+L ++R+ K ++E++ ++R ++ R+ ++R+ E +L ++R++++ R +E +++
Sbjct: 1523 QLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSR-QERDRKF 1581
Query: 439 KAEKAEITRFFQKPKTPQAPKTLAGSCGKFAPFEIKEHMVLAPRRRTAFHPD---LCSQL 495
+ E+ ++ R Q+ K + + L G+ L R F D L +
Sbjct: 1582 RLEEQKVRRQEQERKFMEDEQQLRRQEGQ---------QQLRQERDRKFREDEQLLQERE 1632
Query: 496 DQLLQQQSGEFSFLKD 511
+Q L +Q + FL++
Sbjct: 1633 EQQLHRQERDRKFLEE 1648
Score = 54.3 bits (129), Expect = 5e-07
Identities = 33/122 (27%), Positives = 73/122 (59%), Gaps = 10/122 (8%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAK---EEAKKKKEEEKELKEKERR 387
E +L +R++++L +Q + R EE+ +L+ + + + + +K +EEE+ L+E E +
Sbjct: 1623 EDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQ 1682
Query: 388 EKR--EKDEKEKAEKQRLKEERRK-----ERQEALEAKLEEKRKKEEEKRLREEEKRIKA 440
+ R E+D K + E+Q+L+ + R+ E Q+ +LE K ++EE+ R E+++++
Sbjct: 1683 QLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRR 1742
Query: 441 EK 442
++
Sbjct: 1743 QE 1744
Score = 53.9 bits (128), Expect = 7e-07
Identities = 28/105 (26%), Positives = 65/105 (61%), Gaps = 2/105 (1%)
Query: 338 QRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEK 397
+R ++RL + LR +RE + L+ E ++ +E+ +EEEKE + ++RRE+ ++ + +
Sbjct: 778 ERGRQRLSARPPLREQRERQ--LRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLE 835
Query: 398 AEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEK 442
E+Q + ER ++ QE + E++ ++ +++ R+++ R + E+
Sbjct: 836 EEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEE 880
Score = 53.5 bits (127), Expect = 9e-07
Identities = 38/133 (28%), Positives = 75/133 (56%), Gaps = 13/133 (9%)
Query: 331 EKNKLRLQRDQER---LGKQLKLRAE--REEKEKLKEEA-KRAKEEAKKKKEEEKELKEK 384
E+ LR +R++ R L +Q + E +EE++ L+EE KR ++E +++ EE+EL+++
Sbjct: 1120 EEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQE 1179
Query: 385 ERREKREKDEKEKAEKQR-------LKEERRKERQEALEAKLEEKRKKEEEKRLREEEKR 437
E + RE+ EK + E++R L+ ++RK+R + + + K + E EK + +
Sbjct: 1180 EEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNK 1239
Query: 438 IKAEKAEITRFFQ 450
+ + E +F Q
Sbjct: 1240 VYCKGRENEQFRQ 1252
Score = 53.1 bits (126), Expect = 1e-06
Identities = 31/121 (25%), Positives = 74/121 (61%), Gaps = 10/121 (8%)
Query: 336 RLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREK--REKD 393
R R +ER ++ + E EEKE+ + + +R +E+ + EEE++L+ +ER ++ E+D
Sbjct: 796 RQLRAEERQQREQRFLPEEEEKEQRRRQ-RREREKELQFLEEEEQLQRRERAQQLQEEED 854
Query: 394 EKEKAEKQRLKEERRKERQEALEAKLEEKRKKEE-------EKRLREEEKRIKAEKAEIT 446
++ +++R +E+R++++ + + E KR++ +++LR+E++ ++ E+ E+
Sbjct: 855 GLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQ 914
Query: 447 R 447
R
Sbjct: 915 R 915
Score = 53.1 bits (126), Expect = 1e-06
Identities = 34/108 (31%), Positives = 62/108 (57%), Gaps = 5/108 (4%)
Query: 331 EKNKLRLQRDQERLGKQL--KLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERRE 388
E+ + LQ +Q+ ++L K R E + +++ ++E R +E +K EEE+ E+E ++
Sbjct: 1704 ERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQ 1763
Query: 389 KREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEK 436
R +E+ K R +E+ R+ER+E E RK EE++LR+E +
Sbjct: 1764 LR---RQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQERE 1808
Score = 52.0 bits (123), Expect = 3e-06
Identities = 28/118 (23%), Positives = 68/118 (57%), Gaps = 6/118 (5%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKR 390
E+ + Q+ +E + + + EEK + + A+ ++++E + +E+++RE+R
Sbjct: 750 EEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQR 809
Query: 391 ---EKDEKEKAEKQRLKEERR---KERQEALEAKLEEKRKKEEEKRLREEEKRIKAEK 442
E++EKE+ +QR + E+ E +E L+ + ++ +EEE L+E+++R ++++
Sbjct: 810 FLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQE 867
Score = 52.0 bits (123), Expect = 3e-06
Identities = 36/138 (26%), Positives = 76/138 (55%), Gaps = 7/138 (5%)
Query: 317 PLRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKE 376
PLRR + + E+ ++ ++ L ++ +LR + E++ LKEE + +E +++
Sbjct: 1352 PLRRQERD--RKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLR 1409
Query: 377 EEKELK---EKERREKREKDEKEKAEKQ--RLKEERRKERQEALEAKLEEKRKKEEEKRL 431
++++ K E+++ ++E+D K + E+Q R +E RK +E + + E RK EE++L
Sbjct: 1410 QDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQL 1469
Query: 432 REEEKRIKAEKAEITRFF 449
+E + + + E R F
Sbjct: 1470 LQEREEQQLHRQERDRKF 1487
Score = 52.0 bits (123), Expect = 3e-06
Identities = 38/139 (27%), Positives = 76/139 (54%), Gaps = 22/139 (15%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEA--------KKKKEEEKELK 382
E+ R +R+++ L ++ +LR ER K + +E+ + +EE +K EEE++L+
Sbjct: 1436 EQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLR 1495
Query: 383 EKERREKREKDEKEKAEKQR--LKEERRKERQEALEAKLEE-----------KRKKEEEK 429
+ER K + E E +R L+EE++ RQ+ L+E +R+++ ++
Sbjct: 1496 RQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDR 1555
Query: 430 RLREEEK-RIKAEKAEITR 447
+ REEE+ R + E+ +++R
Sbjct: 1556 KFREEEQLRQEREEQQLSR 1574
Score = 51.6 bits (122), Expect = 3e-06
Identities = 35/130 (26%), Positives = 72/130 (55%), Gaps = 19/130 (14%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKR 390
E+ + +L+R+Q+ +Q +L+ E EE+E+L++ KR EE ++ E+EL E+E+ + R
Sbjct: 641 ERRQQQLRREQQERREQ-RLKRE-EEEERLEQRLKREHEEERR----EQELAEEEQEQAR 694
Query: 391 EK-------------DEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKR 437
E+ E + + + R++E Q + + E++R++E E + +EEE+
Sbjct: 695 ERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERA 754
Query: 438 IKAEKAEITR 447
+ ++ E R
Sbjct: 755 HRQQQEEEQR 764
Score = 51.2 bits (121), Expect = 5e-06
Identities = 35/126 (27%), Positives = 77/126 (61%), Gaps = 17/126 (13%)
Query: 336 RLQRDQERLGKQLKLRAEREEKEK--LKEEAKRAKEEA---------KKKKEEEKELKEK 384
+ + D++ L ++ + + R+E+++ L+EE + ++E +K +EEE+ L+E
Sbjct: 1620 KFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEG 1679
Query: 385 ERRE--KREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEK-RIKAE 441
E ++ ++E+D K + E+Q+L RR+ER+ + ++ R++E E++ REEE+ R + E
Sbjct: 1680 EEQQLRRQERDRKFREEEQQL---RRQERERKFLQEEQQLRRQELERKFREEEQLRQETE 1736
Query: 442 KAEITR 447
+ ++ R
Sbjct: 1737 QEQLRR 1742
Score = 50.4 bits (119), Expect = 8e-06
Identities = 32/131 (24%), Positives = 76/131 (58%), Gaps = 12/131 (9%)
Query: 323 KKFVKGSTEKNKLRLQR--DQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKE 380
+KF++ E+ +LR Q Q R + K R E + +++ +E+ +E +K + EE++
Sbjct: 1531 RKFLQ---EEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQK 1587
Query: 381 LKEKERREKREKDEKE---KAEKQRLKEER----RKERQEALEAKLEEKRKKEEEKRLRE 433
++ +E+ K +DE++ + +Q+L++ER R++ Q E + ++ ++E +++ E
Sbjct: 1588 VRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLE 1647
Query: 434 EEKRIKAEKAE 444
EE +++ ++ E
Sbjct: 1648 EEPQLRRQERE 1658
Score = 49.3 bits (116), Expect = 2e-05
Identities = 32/135 (23%), Positives = 72/135 (53%), Gaps = 11/135 (8%)
Query: 327 KGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEE-------- 378
K ++ +L +Q ++L+ R + E+L + + +E +++ EEE
Sbjct: 140 KRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGH 199
Query: 379 --KELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEK 436
+E ++E+ +RE E + ++ K+++R+ERQ+ + + EEK ++ E LR+EE+
Sbjct: 200 ETEEFPDEEQLRRRELLELRRKGREE-KQQQRRERQDRVFQEEEEKEWRKRETVLRKEEE 258
Query: 437 RIKAEKAEITRFFQK 451
+++ E+ + R Q+
Sbjct: 259 KLQEEEPQRQRELQE 273
Score = 48.5 bits (114), Expect = 3e-05
Identities = 38/123 (30%), Positives = 72/123 (58%), Gaps = 11/123 (8%)
Query: 331 EKNKLRLQR--DQERLGKQLKL--RAEREEKEKLKEEAKRAKEEAKKK--KEEEKELKEK 384
E+ + RL+R ++ERL ++LK ER E+E +EE ++A+E K + K + + E
Sbjct: 653 ERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEA 712
Query: 385 ERREKREKDEKEKAEKQRLK---EERRKERQEALEAKLEEK--RKKEEEKRLREEEKRIK 439
+ R+ + K E QR + EE+R+ R+ L+ + EE+ R+++EE++ R+ + +
Sbjct: 713 DARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQ 772
Query: 440 AEK 442
AE+
Sbjct: 773 AEE 775
Score = 48.5 bits (114), Expect = 3e-05
Identities = 34/148 (22%), Positives = 73/148 (49%), Gaps = 31/148 (20%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAK---EEAKKKKEEEKELKEKERR 387
E+ K R+ + Q +L + R + K+E +R + EE ++++E E + +E+ER
Sbjct: 695 ERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERA 754
Query: 388 EKREKDEK------------EKAEKQR----------------LKEERRKERQEALEAKL 419
+++++E+ EK+E+ R L+ E R++R++ +
Sbjct: 755 HRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEE 814
Query: 420 EEKRKKEEEKRLREEEKRIKAEKAEITR 447
EEK ++ ++R RE+E + E+ ++ R
Sbjct: 815 EEKEQRRRQRREREKELQFLEEEEQLQR 842
Score = 48.5 bits (114), Expect = 3e-05
Identities = 27/139 (19%), Positives = 78/139 (56%), Gaps = 10/139 (7%)
Query: 323 KKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELK 382
+KF++ E+ R QR ++ L ++ +LR + +++ ++ ++ +EE + ++E E++
Sbjct: 1515 RKFLE--EEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQL 1572
Query: 383 EKERREKREKDEKEKAEKQRLKEE--------RRKERQEALEAKLEEKRKKEEEKRLREE 434
++ R+++ + E++K +Q + + RR+E Q+ L + + K +++E+ E
Sbjct: 1573 SRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQERE 1632
Query: 435 EKRIKAEKAEITRFFQKPK 453
E+++ ++ + ++P+
Sbjct: 1633 EQQLHRQERDRKFLEEEPQ 1651
Score = 47.8 bits (112), Expect = 5e-05
Identities = 41/184 (22%), Positives = 84/184 (45%), Gaps = 50/184 (27%)
Query: 317 PLRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKE 376
P +R ++ + E+ +L+ + +Q +Q K R ERE + + +EE +R K + + + E
Sbjct: 1158 PEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDE 1217
Query: 377 EE-------------------------------KELKEKERREKR----------EKDEK 395
++ ++L++ + R+++ E+ E+
Sbjct: 1218 DQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQER 1277
Query: 396 EKAEKQR--------LKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITR 447
++ +++R EE + ER+E EAK + RK +EEK+L EE+ K + E R
Sbjct: 1278 DREQERRRWQQRDRHFPEEEQLEREEQKEAKRRD-RKSQEEKQLLREEREEKRRRQETDR 1336
Query: 448 FFQK 451
F++
Sbjct: 1337 KFRE 1340
Score = 47.4 bits (111), Expect = 7e-05
Identities = 24/114 (21%), Positives = 64/114 (56%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKR 390
E + R Q+ QE+ + + + E++E+L++ ++ ++E ++ +E + +E+ R E+
Sbjct: 132 EPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEE 191
Query: 391 EKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAE 444
+ + E + +E + R+E LE + + + +K++++R R++ + E+ E
Sbjct: 192 QLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKE 245
Score = 47.0 bits (110), Expect = 9e-05
Identities = 29/104 (27%), Positives = 61/104 (58%), Gaps = 11/104 (10%)
Query: 351 RAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEK---ERREKREKDEKEKAE-------K 400
RA + KE L ++ +R +E+ ++ + +++L+E+ RR+KR++ E+E AE +
Sbjct: 100 RARCDGKESLLQD-RRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQ 158
Query: 401 QRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAE 444
+RL++ R+ R E L + +E +++EE + E+ + K + E
Sbjct: 159 ERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETE 202
Score = 46.6 bits (109), Expect = 1e-04
Identities = 35/125 (28%), Positives = 70/125 (56%), Gaps = 13/125 (10%)
Query: 345 GKQLKLRAEREEKEKLKEEAK--RAKEEAKKKKEEEKELKEKERREKREKDEK----EKA 398
GK+ L+ R+E+++ + E + + +EE +++ ++++ +E+E E E+ EK E+
Sbjct: 105 GKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQR 164
Query: 399 EKQRLKEE---RRKERQEALEAKLEEKR----KKEEEKRLREEEKRIKAEKAEITRFFQK 451
++QR EE +R+E QE E + EE++ K E + +EE+ + E E+ R ++
Sbjct: 165 DRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGRE 224
Query: 452 PKTPQ 456
K Q
Sbjct: 225 EKQQQ 229
Score = 46.6 bits (109), Expect = 1e-04
Identities = 34/154 (22%), Positives = 79/154 (51%), Gaps = 43/154 (27%)
Query: 332 KNKLRLQRDQERLGKQLKLR--AEREEKEKLKEEAKRAKEEAK----------------- 372
+ +L+ + ++ERL ++LK ER E+E +EE ++A+E K
Sbjct: 656 EQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADAR 715
Query: 373 ---------KKKEEEKELKEKERREKREKD----EKEKAEKQRLKEERRKERQEALEAKL 419
K++ + + +++E+R +RE + E+E+A +Q+ +EE+R++ +A+
Sbjct: 716 QSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEE 775
Query: 420 EEKR-----------KKEEEKRLREEEKRIKAEK 442
+ +R +++ E++LR EE++ + ++
Sbjct: 776 KSERGRQRLSARPPLREQRERQLRAEERQQREQR 809
Score = 46.2 bits (108), Expect = 1e-04
Identities = 32/124 (25%), Positives = 71/124 (57%), Gaps = 15/124 (12%)
Query: 336 RLQRDQERLGKQLKLRAEREEKEKLKEE--AKRAKEEAKKKKE-------EEKELKEKER 386
R Q Q R +Q + R RE + + +EE A R ++E +++++ EEK + ++R
Sbjct: 724 RKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQR 783
Query: 387 REKR-----EKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRI-KA 440
R +++ + +AE+++ +E+R +E E + ++R++E+E + EEE+++ +
Sbjct: 784 LSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRR 843
Query: 441 EKAE 444
E+A+
Sbjct: 844 ERAQ 847
Score = 44.3 bits (103), Expect = 6e-04
Identities = 24/83 (28%), Positives = 51/83 (61%), Gaps = 1/83 (1%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKR 390
E+ +L+L+ ++RL +Q + R R E++ +E R +E+ ++EE+K +E+ER+ +
Sbjct: 1824 EEEQLQLEEQEQRL-RQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLRE 1882
Query: 391 EKDEKEKAEKQRLKEERRKERQE 413
E +++ E+QR ++ + QE
Sbjct: 1883 EHIRRQQKEEQRHRQVGEIKSQE 1905
Score = 43.9 bits (102), Expect = 7e-04
Identities = 22/119 (18%), Positives = 66/119 (55%), Gaps = 1/119 (0%)
Query: 327 KGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKER 386
+ + NK+ + + +QL+ R+ + + + +++ + +++E + ++++R
Sbjct: 1232 ENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDR 1291
Query: 387 R-EKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAE 444
+ E+ E+E+ ++ + ++ + +E ++ L + EEKR+++E R EE+++ E+ E
Sbjct: 1292 HFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREE 1350
Score = 39.3 bits (90), Expect = 0.018
Identities = 20/76 (26%), Positives = 45/76 (59%), Gaps = 2/76 (2%)
Query: 362 EEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEE 421
+E KRA+ + K+ +++ +E +RR + + E+ QR +++R+++ +E E EE
Sbjct: 96 DEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEG--EE 153
Query: 422 KRKKEEEKRLREEEKR 437
+ +K+E R+ ++R
Sbjct: 154 QSEKQERLEQRDRQRR 169
Score = 35.0 bits (79), Expect = 0.33
Identities = 21/78 (26%), Positives = 47/78 (60%), Gaps = 5/78 (6%)
Query: 369 EEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEE----RRKERQEALEAKLEEKRK 424
+E K+ + + KE ++RR++ ++ E ++Q L+EE RR++RQE E + +
Sbjct: 96 DEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQ-LEEEPGQRRRQKRQEQERELAEGEEQ 154
Query: 425 KEEEKRLREEEKRIKAEK 442
E+++RL + +++ + E+
Sbjct: 155 SEKQERLEQRDRQRRDEE 172
>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
Length = 749
Score = 76.6 bits (187), Expect = 1e-13
Identities = 56/186 (30%), Positives = 96/186 (51%), Gaps = 20/186 (10%)
Query: 268 ESEVLESFPEEDSV--LSHSSLSSPSSTSSPEGPPAP-PKQHSSTSPFPTSTPLRRITKK 324
E+ V E P E V + + +P+S +P PAP P + P+ST + K
Sbjct: 409 EATVEERTPAEPEVGPAAPAMAPAPASAPAPASAPAPAPVPTPAMVSAPSSTVNASASVK 468
Query: 325 FVKGSTEKNKL-RLQRDQERLGKQLKLRAERE-------EKEKLKEEAKRAKEEAKKKKE 376
G+T+ + RL ++ RL ++ + + ERE E++K +E A+R EE ++E
Sbjct: 469 TSAGTTDPEEATRLLAEKRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRRE 528
Query: 377 EEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEK 436
EE E E+ ++E+ + +AE++ L+E ER + R+KEEE R+REE +
Sbjct: 529 EESRRLEAEQAREKEEQLQRQAEERALREREEAERAQ---------RQKEEEARVREEAE 579
Query: 437 RIKAEK 442
R++ E+
Sbjct: 580 RVRQER 585
Score = 75.9 bits (185), Expect = 2e-13
Identities = 59/212 (27%), Positives = 111/212 (52%), Gaps = 12/212 (5%)
Query: 234 KGKVPMVVLQDILAVR--PPQIKSLPATPQGKNMTPESEVLESFPEEDSVLSHSSLSSPS 291
KG+ P+V +++ P + + PA P + S P V + + +S+PS
Sbjct: 399 KGRAPLVKVEEATVEERTPAEPEVGPAAPAMAPAPASAPAPASAPAPAPVPTPAMVSAPS 458
Query: 292 STSSPEGPPAPPKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQ---- 347
ST + A K + T+ +T L ++ + EK + R +R+QE L +Q
Sbjct: 459 STVNAS---ASVKTSAGTTDPEEATRLLAEKRRLAREQREKEE-RERREQEELERQKREE 514
Query: 348 LKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEER 407
L R E + +EE++R + E ++KEE+ + ++ E R RE++E E+A++Q+ +E R
Sbjct: 515 LAQRVAEERTTRREEESRRLEAEQAREKEEQLQ-RQAEERALREREEAERAQRQKEEEAR 573
Query: 408 RKERQEALEAKLEEKRKKEEEKRLREEEKRIK 439
+E E + + E+ ++EE++RL E +KR++
Sbjct: 574 VREEAERVRQEREKHFQREEQERL-ERKKRLE 604
Score = 52.4 bits (124), Expect = 2e-06
Identities = 32/98 (32%), Positives = 58/98 (59%), Gaps = 8/98 (8%)
Query: 340 DQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERR--EKREKDEKEK 397
D++RL ++ R E EK+ E + E + ++ EK L+E+++R E+R+K+E+ +
Sbjct: 65 DRQRLARE---RREEREKQLAAREIVWLEREERARQHYEKHLEERKKRLEEQRQKEERRR 121
Query: 398 A---EKQRLKEERRKERQEALEAKLEEKRKKEEEKRLR 432
A EK+R + E KER EA+ + E+ +K ++K R
Sbjct: 122 AAVEEKRRQRLEEDKERHEAVVRRTMERSQKPKQKHNR 159
Score = 47.4 bits (111), Expect = 7e-05
Identities = 26/71 (36%), Positives = 44/71 (61%), Gaps = 2/71 (2%)
Query: 376 EEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEK--RKKEEEKRLRE 433
EE L ++RR RE+ EKE+ E++ +E R++R+E + EE+ R++EE +RL
Sbjct: 477 EEATRLLAEKRRLAREQREKEERERREQEELERQKREELAQRVAEERTTRREEESRRLEA 536
Query: 434 EEKRIKAEKAE 444
E+ R K E+ +
Sbjct: 537 EQAREKEEQLQ 547
Score = 47.0 bits (110), Expect = 9e-05
Identities = 31/102 (30%), Positives = 57/102 (55%), Gaps = 14/102 (13%)
Query: 355 EEKEKLKEEAKRAKEEAKKKKEE---EKELKEKERREKREKDEKEKAEKQRLKEERRKER 411
+++++L E + +E+ +E E+E + ++ EK ++ K++ E+QR KEERR+
Sbjct: 64 DDRQRLARERREEREKQLAAREIVWLEREERARQHYEKHLEERKKRLEEQRQKEERRR-- 121
Query: 412 QEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITRFFQKPK 453
A +EEKR+ +RL E+++R +A QKPK
Sbjct: 122 -----AAVEEKRR----QRLEEDKERHEAVVRRTMERSQKPK 154
Score = 45.1 bits (105), Expect = 3e-04
Identities = 23/76 (30%), Positives = 45/76 (59%)
Query: 382 KEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAE 441
+++ RE+RE+ EK+ A ++ + ER + ++ E LEE++K+ EE+R +EE +R E
Sbjct: 66 RQRLARERREEREKQLAAREIVWLEREERARQHYEKHLEERKKRLEEQRQKEERRRAAVE 125
Query: 442 KAEITRFFQKPKTPQA 457
+ R + + +A
Sbjct: 126 EKRRQRLEEDKERHEA 141
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 72.8 bits (177), Expect = 1e-12
Identities = 38/113 (33%), Positives = 82/113 (72%), Gaps = 5/113 (4%)
Query: 336 RLQRDQERLGKQLKLRAE---REEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREK 392
+++ +E++ +Q K+R + R+E+EK++E+ KR ++EAK ++EEK +++E+ ++E+
Sbjct: 345 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEE 404
Query: 393 DEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEI 445
+E+ EK +EE+ E++E ++ + EEK +++EEK +RE+EK+I+ ++ +I
Sbjct: 405 MMQEQEEKMGEQEEKMWEQEEEMQEQ-EEKMRRQEEK-IREQEKKIREQEEKI 455
Score = 67.0 bits (162), Expect = 8e-11
Identities = 35/109 (32%), Positives = 75/109 (68%), Gaps = 3/109 (2%)
Query: 337 LQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKE 396
+Q +E++G+Q + E+EE+ + +EE R +EE K +E+EK+++E+E + + +++ +
Sbjct: 406 MQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEE--KIREQEKKIREQEEKIREQEEMMQ 463
Query: 397 KAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEI 445
+ E++ ++E + QEA + EEK +++EEK +RE+EK+I+ ++ +I
Sbjct: 464 EQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEK-IREQEKKIREQEEKI 511
Score = 65.9 bits (159), Expect = 2e-10
Identities = 38/112 (33%), Positives = 74/112 (66%), Gaps = 7/112 (6%)
Query: 336 RLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEK 395
+++ +E++ +Q ++ E+EEK ++E K ++EAK +++EEK +++E+ ++EK +
Sbjct: 447 KIREQEEKIREQEEMMQEQEEKMG-EQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIR 505
Query: 396 EKAEKQRLKEERRKERQEAL---EAKL---EEKRKKEEEKRLREEEKRIKAE 441
E+ EK R +EE +E++E + E K+ EEK +++EEK R+EEK + E
Sbjct: 506 EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQE 557
Score = 64.3 bits (155), Expect = 5e-10
Identities = 47/154 (30%), Positives = 89/154 (57%), Gaps = 32/154 (20%)
Query: 320 RITKKFVKGSTEKNKL-----RLQRDQERLGKQL-----KLRAEREE-----------KE 358
++ K +K E+ KL +LQ + + LGK+L KL+A+ EE +E
Sbjct: 229 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 288
Query: 359 KLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEK-EKAEKQRLKEERRKERQE---A 414
K+ + ++ +E +K +E+E++++E+E + +R+++ EK EK R +EE E++E
Sbjct: 289 KMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRE 348
Query: 415 LEAKL-------EEKRKKEEEKRLREEEKRIKAE 441
LE K+ E++ K++EE+++RE+EKR + E
Sbjct: 349 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 382
Score = 64.3 bits (155), Expect = 5e-10
Identities = 40/125 (32%), Positives = 77/125 (61%), Gaps = 4/125 (3%)
Query: 320 RITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEK 379
+I ++ K ++ K+R Q +E++ +Q ++ E+EEK + +EE KEE ++ EE+
Sbjct: 296 KIQEREEKIQEQEEKIREQ--EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 353
Query: 380 ELKEK--ERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKR 437
+EK E+ EKR+++EK + +++R ++E + RQE + EEK +++EE +EEK
Sbjct: 354 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKM 413
Query: 438 IKAEK 442
+ E+
Sbjct: 414 GEQEE 418
Score = 64.3 bits (155), Expect = 5e-10
Identities = 36/118 (30%), Positives = 78/118 (66%), Gaps = 8/118 (6%)
Query: 336 RLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEE---EKELKEKERREKREK 392
++Q +E++ +Q + E+EEK + +EE KEE +++EE EKE K +E EK +
Sbjct: 296 KIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHE 355
Query: 393 DEKEKAEKQRLKEE---RRKERQEALEAKL--EEKRKKEEEKRLREEEKRIKAEKAEI 445
EK + ++++ +EE R +E+++ EAK+ +E++ +E+E+++RE+E+ ++ ++ ++
Sbjct: 356 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKM 413
Score = 63.5 bits (153), Expect = 9e-10
Identities = 49/146 (33%), Positives = 84/146 (57%), Gaps = 13/146 (8%)
Query: 303 PKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKL--RL-QRDQERLGKQLKLRAEREEKEK 359
P+Q L+ ++ K ++ E+N+L RL Q+ +E++ +Q + EREEK +
Sbjct: 247 PQQQLQAEADHLGKELQSVSAK-LQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQ 305
Query: 360 LKEEAKRAKEEAKKKKEEEK-ELKEKERREKR---EKDEK-----EKAEKQRLKEERRKE 410
+EE R +EE +++EE E +EK RR++ EK+EK EK +Q E+ ++
Sbjct: 306 EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 365
Query: 411 RQEALEAKLEEKRKKEEEKRLREEEK 436
RQE + + +EKR+++E K R+EEK
Sbjct: 366 RQEEEKIREQEKRQEQEAKMWRQEEK 391
Score = 63.2 bits (152), Expect = 1e-09
Identities = 38/139 (27%), Positives = 89/139 (64%), Gaps = 13/139 (9%)
Query: 320 RITKKFVKGSTEKNKLRLQRD-----QERLGKQLKLRAEREEKEKLKEEAKRAKE---EA 371
+I ++ K ++ K+R Q + +E++ +Q ++ E+EEK + EE +E E
Sbjct: 303 KIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ 362
Query: 372 KKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEAL---EAKLEEKRKK--E 426
++K++EE++++E+E+R+++E + EK R +EE+ +E++E + E K+ E+ +K E
Sbjct: 363 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWE 422
Query: 427 EEKRLREEEKRIKAEKAEI 445
+E+ ++E+E++++ ++ +I
Sbjct: 423 QEEEMQEQEEKMRRQEEKI 441
Score = 62.4 bits (150), Expect = 2e-09
Identities = 32/109 (29%), Positives = 71/109 (65%), Gaps = 3/109 (2%)
Query: 337 LQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKE 396
+Q +E++G+Q E+E K + +EE R +EE K +E+EK+++E+E + + +++ +
Sbjct: 462 MQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEE--KIREQEKKIREQEEKIREQEEMMQ 519
Query: 397 KAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEI 445
+ E++ ++E + QE + EEK +++EEK +RE+E R++ ++ ++
Sbjct: 520 EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK-MREQEVRLRQQEEKM 567
Score = 62.0 bits (149), Expect = 3e-09
Identities = 29/117 (24%), Positives = 80/117 (68%), Gaps = 3/117 (2%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAE--REEKEKLKEEAKRAKEEAKKKKEEEKELKEKERRE 388
E+ K+R Q ++ ++ + E RE++EK++E+ + +E+ +K E+E+++ E+E E
Sbjct: 368 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEE-E 426
Query: 389 KREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEI 445
+E++EK + ++++++E+ +K R++ + + +E+ +E+E+++ E+E ++ ++A++
Sbjct: 427 MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKM 483
Score = 61.2 bits (147), Expect = 4e-09
Identities = 29/112 (25%), Positives = 70/112 (62%), Gaps = 5/112 (4%)
Query: 336 RLQRDQERLGKQLKLRAEREEK-----EKLKEEAKRAKEEAKKKKEEEKELKEKERREKR 390
+++ +E++ +Q ++ E+EEK EK+ E+ + +E+ +K + +E++++E+E++ +
Sbjct: 391 KIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIRE 450
Query: 391 EKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEK 442
++++ + E+ ++E + QE + E K +++EEK R+EEK + EK
Sbjct: 451 QEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEK 502
Score = 61.2 bits (147), Expect = 4e-09
Identities = 32/117 (27%), Positives = 72/117 (61%), Gaps = 5/117 (4%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEK-----EKLKEEAKRAKEEAKKKKEEEKELKEKE 385
++ + +++R +E++ +Q K E+EEK E ++E+ ++ E+ K E+E +++E+E
Sbjct: 428 QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQE 487
Query: 386 RREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEK 442
+ +R++++ + EK+ ++E + QE + + EEK ++EEK +EEK + E+
Sbjct: 488 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 544
Score = 59.3 bits (142), Expect = 2e-08
Identities = 36/172 (20%), Positives = 100/172 (58%), Gaps = 7/172 (4%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKR 390
++ + ++ R +E++ +Q + RE++E ++E+ ++ E+ +K E+E+E++E+E + +R
Sbjct: 379 QEQEAKMWRQEEKIREQEE--KIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRR 436
Query: 391 EKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITRFFQ 450
+ +EK + ++++++E+ K R++ + +E++ E+E ++ E+E +++ ++ ++ R Q
Sbjct: 437 Q-EEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRR--Q 493
Query: 451 KPKTPQAPKTLAGSCGKFAPFEIKEHMVLAPRRRTAFHPDLCSQLDQLLQQQ 502
+ K + K + K E +E M + +C Q +++ +Q+
Sbjct: 494 EEKIREQEKKIREQEEKIR--EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 543
Score = 49.3 bits (116), Expect = 2e-05
Identities = 28/102 (27%), Positives = 64/102 (62%), Gaps = 5/102 (4%)
Query: 327 KGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKER 386
+G + + ++Q +E++ +Q + E+E+K + +EE R +EE ++ +EEK +++E+
Sbjct: 473 EGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE-QEEKMWEQEEK 531
Query: 387 REKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEE 428
++E+ +E+ EK R +EE+ +E+ E +L ++ +K +E
Sbjct: 532 MCEQEEKMQEQEEKMRRQEEKMREQ----EVRLRQQEEKMQE 569
Score = 41.6 bits (96), Expect = 0.004
Identities = 32/131 (24%), Positives = 70/131 (53%), Gaps = 14/131 (10%)
Query: 320 RITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREE----KEKLKEEAKRAKEEAKKKK 375
++ +K +EK++++L K+LK + ER + +++L+ EA +E +
Sbjct: 213 KLQEKLQLVESEKSEIQLNV------KELKRKLERAKLLLPQQQLQAEADHLGKELQSVS 266
Query: 376 EE-EKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKL---EEKRKKEEEKRL 431
+ + +++E E + + ++EK +Q K + R+E+ + E K+ EEK +++EE
Sbjct: 267 AKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMW 326
Query: 432 REEEKRIKAEK 442
+EEK + E+
Sbjct: 327 EKEEKMRRQEE 337
Score = 38.9 bits (89), Expect = 0.023
Identities = 34/128 (26%), Positives = 59/128 (46%), Gaps = 25/128 (19%)
Query: 340 DQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEE-----------------KELK 382
D+E K KL+ + + E K E + +E K+K E KEL+
Sbjct: 204 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ 263
Query: 383 EKERREKREKDEKE--------KAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREE 434
+ + + +E E + EK +EE+ +ER+E ++ + E+ R++EE+ R +EE
Sbjct: 264 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEE 323
Query: 435 EKRIKAEK 442
K EK
Sbjct: 324 MMWEKEEK 331
Score = 35.0 bits (79), Expect = 0.33
Identities = 31/109 (28%), Positives = 55/109 (50%), Gaps = 13/109 (11%)
Query: 341 QERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKEL----KEKERREKREKDEKE 396
+ER L+L E+LKE+ + +E+ + + E+ E+ KE +R+ +R K
Sbjct: 188 KERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLP 247
Query: 397 KAEKQRLKEERRKERQEA---LEAKLEEK------RKKEEEKRLREEEK 436
+ + Q + KE Q L+A++EE +++EEK R+EEK
Sbjct: 248 QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEK 296
Score = 32.3 bits (72), Expect = 2.2
Identities = 41/206 (19%), Positives = 92/206 (44%), Gaps = 16/206 (7%)
Query: 251 PQIKSLPATPQGKNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSSTS 310
P LP P T +S++ E+ ++ + H ++PS + K ++ T+
Sbjct: 28 PTHPHLPTHPMMSKETRQSKLAEA---KEQLTDHHPQTNPS-VGTAASDTKKKKINNGTN 83
Query: 311 PFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLK-LRAEREE--------KEKLK 361
P T++ + K S + + L+R+ E + ++ L ++ E + +K
Sbjct: 84 PETTTSGGCHSPEDEQKASHQHQEA-LRRELEAQVQTIRILTCQKTELQMALYYSQHAVK 142
Query: 362 EEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEK--QRLKEERRKERQEALEAKL 419
+ A++ + + K E E+ +K+KA++ + L +ER E +
Sbjct: 143 QLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTI 202
Query: 420 EEKRKKEEEKRLREEEKRIKAEKAEI 445
++ KE+ +L+E+ + +++EK+EI
Sbjct: 203 TDEELKEKNAKLQEKLQLVESEKSEI 228
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 72.0 bits (175), Expect = 2e-12
Identities = 101/411 (24%), Positives = 167/411 (40%), Gaps = 74/411 (18%)
Query: 273 ESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSSTSPFPTSTPLRRITKKFV----KG 328
ES E D L + + P GP + F T ++ +K K
Sbjct: 185 ESGDESDEFLQSRKGQKKNQKNKP-GPNIESGNEDDDASFKIKTVAQKKAEKKERERKKR 243
Query: 329 STEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEE---------------AKRAKEEAKK 373
EK KLR +++E L K +++++E ++ EE A K E
Sbjct: 244 DEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPT 303
Query: 374 KKEEEKELKEKERREKREKDEKEKAEKQRLKEERR---KERQEALEAKL---EEKRKKEE 427
E++ E +K++ +K++K EKE+ EK++ K + K QEAL AKL EE++K+EE
Sbjct: 304 AAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEAL-AKLKEEEERQKREE 362
Query: 428 EKRL---------REEEKRIKAEKAEITRFFQKPKTPQAPKTLAGSCGKFAPFEIKEHMV 478
E+R+ R+EE+R++ EK E + +K + + K GK +E
Sbjct: 363 EERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKE-----GKLLTKSQREARA 417
Query: 479 LAPRRRTAFHPDLCSQLDQLLQQQSGEFSFLKDLKGRQPL------RSGPTHVSTRNADI 532
A +LLQ Q E L ++P+ + P + ++
Sbjct: 418 RAEATL------------KLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSE 465
Query: 533 FNSDVVIVERGKGDGVPERRKFGRMKLLQFCENHRPAYWGTW-------------NKKTA 579
VE + GVPE+ + + E+ A W K
Sbjct: 466 SMELCAAVEVME-QGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVH 524
Query: 580 LIRARDPWAQDTKLLDYEVDSDEEWEEEEPGESLSHSEGDDDDDMGEDEDE 630
+ +P ++ + + E D + E EEEE GES SEGD++D+ DE +
Sbjct: 525 IEVKENPEEEEEEEEEEEEDEESEEEEEEEGES-EGSEGDEEDEKVSDEKD 574
Score = 63.2 bits (152), Expect = 1e-09
Identities = 53/194 (27%), Positives = 98/194 (50%), Gaps = 19/194 (9%)
Query: 263 KNMTPESEVLESFPEEDSVLSHSSLSS---PSSTSSPEGPPAPPKQHSSTSPFPTSTPLR 319
K+ + + E F EE++V S ++ + P+S E P A + +
Sbjct: 264 KDQSKQKESQRKF-EEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDK--------K 314
Query: 320 RITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEK 379
+ KK KG E+ ++++++ + ++A +E KLKEE +R K E +++ + +
Sbjct: 315 KKDKKKKKGEKEEK----EKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLE 370
Query: 380 ELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIK 439
EL+ K R++ E+ E+EK E+++ KE+ RKER + E KL K ++E R K ++
Sbjct: 371 ELEAK--RKEEERLEQEKRERKKQKEKERKERLKK-EGKLLTKSQREARARAEATLKLLQ 427
Query: 440 AEKAEITRFFQKPK 453
A+ E+ PK
Sbjct: 428 AQGVEVPSKDSLPK 441
Score = 47.8 bits (112), Expect = 5e-05
Identities = 35/107 (32%), Positives = 52/107 (48%), Gaps = 13/107 (12%)
Query: 349 KLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEK---QRLKE 405
K+ E +E + +EE + +EE ++ +EEE+E E E E E+DEK EK + L +
Sbjct: 522 KVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDK 581
Query: 406 ERRKERQEALEAKLEEKRKKEE----------EKRLREEEKRIKAEK 442
+ KE E ++ R KEE EKR E K + EK
Sbjct: 582 KPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKNVNTEK 628
Score = 38.9 bits (89), Expect = 0.023
Identities = 26/96 (27%), Positives = 49/96 (51%), Gaps = 4/96 (4%)
Query: 352 AEREEKEKLKEEAKR--AKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRK 409
A EE EK++ KE ++++EEE+E +E E E+ E++E E + +E+ +
Sbjct: 510 ASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKV 569
Query: 410 ERQEALEAKLEEKRKKE--EEKRLREEEKRIKAEKA 443
++ L++K KE + ++ R K E+A
Sbjct: 570 SDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERA 605
Score = 38.5 bits (88), Expect = 0.030
Identities = 39/214 (18%), Positives = 92/214 (42%), Gaps = 20/214 (9%)
Query: 243 QDILAVRPPQIKSLPATPQGKNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAP 302
++ +AV+P + T + K + +SF + DS S T+ P+
Sbjct: 76 RETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPK----- 130
Query: 303 PKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKE 362
+ +S + ++ KK KG +K+ + +E + + +K+KE
Sbjct: 131 VEMYSGSDD---DDDFNKLPKK-AKGKAQKSNKKWDGSEE----------DEDNSKKIKE 176
Query: 363 EAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEK 422
+ R + E ++ L+ ++ ++K +K++ + +++ + + + K EK
Sbjct: 177 RS-RINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEK 235
Query: 423 RKKEEEKRLREEEKRIKAEKAEITRFFQKPKTPQ 456
+++E +KR E+ K K ++ E +K ++ Q
Sbjct: 236 KERERKKRDEEKAKLRKLKEKEELETGKKDQSKQ 269
Score = 37.7 bits (86), Expect = 0.052
Identities = 118/623 (18%), Positives = 223/623 (35%), Gaps = 105/623 (16%)
Query: 328 GSTEKNK----LRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKE 383
G +KNK + D + L +++ +E+E K + K+ KE+ K+ +E+ LKE
Sbjct: 2 GKKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKE 61
Query: 384 KER-----------REKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLR 432
E RE E E++ ++++K+ Q+ + ++ +E E +
Sbjct: 62 LEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDS 121
Query: 433 EEEKRIKAEKAEITRFFQKPKTPQAPKTLAGSCGKF------APFEIKEHMVLAPRRRTA 486
+ +K K + + + PK G K + + + R R
Sbjct: 122 KSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRIN 181
Query: 487 FHPDLCSQLDQLLQQQSGEFSFLKDLKGRQPLRSGPTHVSTRNADIFNSDVVIVERGKGD 546
+ + D+ LQ + G+ K Q + GP S D + + V + K +
Sbjct: 182 SSGESGDESDEFLQSRKGQ-------KKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAE 234
Query: 547 GVPERRKFGRMKLLQFCENHRPAYWGTWNK-KTALIRARDPWAQDTKLLDYEVDSDEEWE 605
RK + + + T K ++ ++ + ++T VD+
Sbjct: 235 KKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPA 294
Query: 606 EEEPGESLSHSEGDDDDDMGEDEDEDDGFFVPHGYLSEDEGVTEECADPENHKVRQKLKA 665
EE E+ + +E DD+ G+ + +D + +G EE + E K K
Sbjct: 295 SEEKAETPTAAE---DDNEGDKKKKDK---------KKKKGEKEE-KEKEKKKGPSKATV 341
Query: 666 KEWDEFLAKGKRFRVLQPVKIGCVWAADRDCAGDDLKVLQQFAACFLETLPAQEEQTPKA 725
K E LAK K Q + + +K L++ A +EE+ +
Sbjct: 342 KAMQEALAKLKEEEERQKRE-----------EEERIKRLEELEA------KRKEEERLEQ 384
Query: 726 SKRERRDEQILAQLLPLLHGNVNGSKVIIREFQEHCRRGLLSNHTGSPRSPSTTYLHTPT 785
KRER+ ++ K ++ + S R+ +T L
Sbjct: 385 EKRERKKQK---------------EKERKERLKKEGKLLTKSQREARARAEATLKL---L 426
Query: 786 PSEDAAIPSKSRL--KRLISENSVYEKRP----------DFRMCWYVHPQVLQSFQQEHL 833
++ +PSK L KR I E+ +K P +C V ++E
Sbjct: 427 QAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEET 486
Query: 834 PVPCQWSYVTSVPSAPKEDSGSVPS---TGPSQGTPISLKRKSAGSMCITQFMKKRRHDG 890
P P + A +D ++ S T +G + ++ K +
Sbjct: 487 PPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIE-------------VKENPEE 533
Query: 891 QIGAEDMDGFQADTEEEEEEEGD 913
+ E+ + ++EEEEEEEG+
Sbjct: 534 EEEEEEEEEEDEESEEEEEEEGE 556
Score = 36.2 bits (82), Expect = 0.15
Identities = 33/142 (23%), Positives = 65/142 (45%), Gaps = 12/142 (8%)
Query: 323 KKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEK---LKEEAKRAKEEAKKKKEEEK 379
K+ + ++ K+ Q + + + + ++L A E E+ KEE E +++ E+
Sbjct: 442 KRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDA 501
Query: 380 ELKEKERREKREKDEKEKAEKQRLK--------EERRKERQEALEAKLEEKRKKEEE-KR 430
L + E E+ EK + K ++ EE +E +E E++ EE+ + E E
Sbjct: 502 GLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSE 561
Query: 431 LREEEKRIKAEKAEITRFFQKP 452
EE++++ EK +KP
Sbjct: 562 GDEEDEKVSDEKDSGKTLDKKP 583
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 72.0 bits (175), Expect = 2e-12
Identities = 42/121 (34%), Positives = 79/121 (65%), Gaps = 8/121 (6%)
Query: 327 KGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKER 386
K E+ +LR + +RL +Q + ER E+E+ ++E + + ++++E+E++L E+ER
Sbjct: 667 KKEEEQERLRKAAEAKRLAEQRE--QERREQERREQERREQERREQERREQERQLAEQER 724
Query: 387 REKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLRE----EEKRIKAEK 442
R ++E+ + E+ ++R K R ++ Q L+ +LEEK+KKEE++RL E EE+ KA++
Sbjct: 725 RREQERLQAERELQEREKALRLQKEQ--LQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 782
Query: 443 A 443
A
Sbjct: 783 A 783
Score = 71.2 bits (173), Expect = 4e-12
Identities = 49/139 (35%), Positives = 87/139 (62%), Gaps = 23/139 (16%)
Query: 327 KGSTEKNKLRL--QRDQERLGKQLKLRAEREEKEKLKE--EAKRAKEEAKKKKEE----E 378
K E +LR Q ++ER ++L + + EE+E+L++ EAKR E+ ++++ E E
Sbjct: 640 KQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERRE 699
Query: 379 KELKEKERREK-REKDEKEKAEKQRLKEERR-------KERQEA-------LEAKLEEKR 423
+E +E+ERRE+ R + E++ AE++R +E+ R +ER++A L+ +LEEK+
Sbjct: 700 QERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKK 759
Query: 424 KKEEEKRLREEEKRIKAEK 442
KKEE++RL E + + + EK
Sbjct: 760 KKEEQQRLAERQLQEEQEK 778
Score = 67.8 bits (164), Expect = 5e-11
Identities = 34/135 (25%), Positives = 79/135 (58%), Gaps = 6/135 (4%)
Query: 334 KLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKD 393
++ +R QE ++L+ + EE+ + +E ++ KEE +++ + E K + ++E+
Sbjct: 634 EVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERR 693
Query: 394 EKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKR------LREEEKRIKAEKAEITR 447
E+E+ E++R ++ERR++ + E +L E+ ++ E++R L+E EK ++ +K ++ R
Sbjct: 694 EQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQR 753
Query: 448 FFQKPKTPQAPKTLA 462
++ K + + LA
Sbjct: 754 ELEEKKKKEEQQRLA 768
Score = 65.1 bits (157), Expect = 3e-10
Identities = 62/202 (30%), Positives = 102/202 (50%), Gaps = 34/202 (16%)
Query: 269 SEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPK------QHSSTSPFPTSTPLRRIT 322
SE+ E ED L +PSS P + Q + PTS P R +
Sbjct: 458 SELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAP-RSVM 516
Query: 323 KKFVKGST-----------EKNKLRLQR-DQERLGKQLKLRAEREEKEKLKEEAKRAKEE 370
K F+K +T EK + RL+ ++ +QL+ + E+K + EE K +EE
Sbjct: 517 KSFIKRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREE 576
Query: 371 AKKK----KEEEKELKEKERREKREK----DEK-EKAEKQRLKEERRKERQEALEAKLEE 421
+K +E +++KE+++++ +K DEK EKA+++RL EE+ K++ A + + E
Sbjct: 577 RLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVE 636
Query: 422 KRKKEEE--KRLR----EEEKR 437
R+K+EE +RLR EEE+R
Sbjct: 637 ARRKQEEEARRLRWLQQEEEER 658
Score = 63.5 bits (153), Expect = 9e-10
Identities = 50/146 (34%), Positives = 84/146 (57%), Gaps = 25/146 (17%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAER--EEKEKLKEEAKRAKE-EAKKKKEEEK------EL 381
EK K Q+ + K K + ER EEK K K AK+ +E EA++K+EEE +
Sbjct: 594 EKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQ 653
Query: 382 KEKERR-----EKREKDEKEK----AEKQRLKEERRKER-------QEALEAKLEEKRKK 425
+E+ERR +K++++E+E+ AE +RL E+R +ER QE E + E+ ++
Sbjct: 654 EEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERR 713
Query: 426 EEEKRLREEEKRIKAEKAEITRFFQK 451
E+E++L E+E+R + E+ + R Q+
Sbjct: 714 EQERQLAEQERRREQERLQAERELQE 739
Score = 61.2 bits (147), Expect = 4e-09
Identities = 38/121 (31%), Positives = 68/121 (56%), Gaps = 6/121 (4%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKR 390
E+ K ++ E+ Q+ + E+ ++E+L EE +AK++A KK EE E + K+ E R
Sbjct: 589 EQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEE--KAKKKAAAKKMEEVEARRKQEEEAR 646
Query: 391 E----KDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEIT 446
+ E+E+ Q L +++++E QE L E KR E+ ++ R E++R + E+ E
Sbjct: 647 RLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQE 706
Query: 447 R 447
R
Sbjct: 707 R 707
Score = 52.8 bits (125), Expect = 2e-06
Identities = 30/118 (25%), Positives = 72/118 (61%), Gaps = 10/118 (8%)
Query: 323 KKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELK 382
K+ + ++ + + +R+QER ++ + + RE++ +L E+ +R ++E + + E+EL+
Sbjct: 682 KRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQE---RLQAERELQ 738
Query: 383 EKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKA 440
E+E+ + +K++ ++ L+E+++KE Q+ L E + ++E+EK+ +E KA
Sbjct: 739 EREKALRLQKEQLQR----ELEEKKKKEEQQRL---AERQLQEEQEKKAKEAAGASKA 789
Score = 39.3 bits (90), Expect = 0.018
Identities = 50/212 (23%), Positives = 83/212 (39%), Gaps = 16/212 (7%)
Query: 267 PESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSSTSPF-----PTSTPLRRI 321
PE+ S+P D+ +++S+ + + SSPE P A ++ + P S +R
Sbjct: 393 PENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRS 452
Query: 322 TKKFVKGSTEKNKLRLQRDQERLGKQLK--------LRAEREEKEKLKEEAKRAKEEAKK 373
K+ V E+ L + Q K +R R ++ +
Sbjct: 453 YKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAP 512
Query: 374 KKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEA-KLEE--KRKKEEEKR 430
+ + +K K + E+QRL+ RRKE E L K+EE +R+ EE K
Sbjct: 513 RSVMKSFIKRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKL 572
Query: 431 LREEEKRIKAEKAEITRFFQKPKTPQAPKTLA 462
REE R + E ++ K Q + A
Sbjct: 573 KREERLRKVLQARERVEQMKEEKKKQIEQKFA 604
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 72.0 bits (175), Expect = 2e-12
Identities = 39/116 (33%), Positives = 76/116 (65%), Gaps = 4/116 (3%)
Query: 327 KGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKER 386
K E+ +LR + +RL +Q + ER E+E+ ++E + + ++++E+E++L E+ER
Sbjct: 663 KKEEEQERLRKAAEAKRLAEQRE--QERREQERREQERREQERREQERREQERQLAEQER 720
Query: 387 REKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEK 442
R ++E+ + E+ ++R K R ++ Q L+ +LEEK+KKEE++RL E + + + EK
Sbjct: 721 RREQERLQAERELQEREKALRLQKEQ--LQRELEEKKKKEEQQRLAERQLQEEQEK 774
Score = 68.6 bits (166), Expect = 3e-11
Identities = 61/198 (30%), Positives = 103/198 (52%), Gaps = 30/198 (15%)
Query: 269 SEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPK------QHSSTSPFPTSTPLRRIT 322
SE+ E ED L +PSS P + Q + PTS P R +
Sbjct: 458 SELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAP-RSVM 516
Query: 323 KKFVKGSTEKNKLRLQRDQERLGK-QLKLRAEREEKEKLKEEAKRAKEEAKKKKEEE--- 378
K F+K +T +++++RL + K AE+ ++K++E+ +R EE K K+EE
Sbjct: 517 KSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRK 576
Query: 379 --------KELKEKERREKREK----DEK-EKAEKQRLKEERRKERQEALEAKLEEKRKK 425
+++KE+++++ +K DEK EKA+++RL EE+ K++ A + + E R+K
Sbjct: 577 VLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRK 636
Query: 426 EEE--KRLR----EEEKR 437
+EE +RLR EEE+R
Sbjct: 637 QEEEARRLRWLQQEEEER 654
Score = 67.8 bits (164), Expect = 5e-11
Identities = 34/135 (25%), Positives = 79/135 (58%), Gaps = 6/135 (4%)
Query: 334 KLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKD 393
++ +R QE ++L+ + EE+ + +E ++ KEE +++ + E K + ++E+
Sbjct: 630 EVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERR 689
Query: 394 EKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKR------LREEEKRIKAEKAEITR 447
E+E+ E++R ++ERR++ + E +L E+ ++ E++R L+E EK ++ +K ++ R
Sbjct: 690 EQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQR 749
Query: 448 FFQKPKTPQAPKTLA 462
++ K + + LA
Sbjct: 750 ELEEKKKKEEQQRLA 764
Score = 63.5 bits (153), Expect = 9e-10
Identities = 50/146 (34%), Positives = 84/146 (57%), Gaps = 25/146 (17%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAER--EEKEKLKEEAKRAKE-EAKKKKEEEK------EL 381
EK K Q+ + K K + ER EEK K K AK+ +E EA++K+EEE +
Sbjct: 590 EKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQ 649
Query: 382 KEKERR-----EKREKDEKEK----AEKQRLKEERRKER-------QEALEAKLEEKRKK 425
+E+ERR +K++++E+E+ AE +RL E+R +ER QE E + E+ ++
Sbjct: 650 EEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERR 709
Query: 426 EEEKRLREEEKRIKAEKAEITRFFQK 451
E+E++L E+E+R + E+ + R Q+
Sbjct: 710 EQERQLAEQERRREQERLQAERELQE 735
Score = 61.2 bits (147), Expect = 4e-09
Identities = 38/121 (31%), Positives = 68/121 (56%), Gaps = 6/121 (4%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKR 390
E+ K ++ E+ Q+ + E+ ++E+L EE +AK++A KK EE E + K+ E R
Sbjct: 585 EQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEE--KAKKKAAAKKMEEVEARRKQEEEAR 642
Query: 391 E----KDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEIT 446
+ E+E+ Q L +++++E QE L E KR E+ ++ R E++R + E+ E
Sbjct: 643 RLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQE 702
Query: 447 R 447
R
Sbjct: 703 R 703
Score = 56.6 bits (135), Expect = 1e-07
Identities = 50/229 (21%), Positives = 97/229 (42%), Gaps = 52/229 (22%)
Query: 267 PESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPA------------------------- 301
PE+ S+P D+ +++S+ + + SSPE P A
Sbjct: 393 PENNGNNSWPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRS 452
Query: 302 --------------------PPKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQ 341
PP+ + +SP P S +R + + F+ L
Sbjct: 453 YKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPL-RTFLHTVQRNQMLMTPTSA 511
Query: 342 ER------LGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEK 395
R + + LR + +EKE+ + E R KEEA++ + ++ E ++ R E+ + +
Sbjct: 512 PRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKRE 571
Query: 396 EKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAE 444
E+ K ER ++ +E + ++E+K + +EK + +E+R+ EKA+
Sbjct: 572 ERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAK 620
Score = 52.8 bits (125), Expect = 2e-06
Identities = 30/118 (25%), Positives = 72/118 (61%), Gaps = 10/118 (8%)
Query: 323 KKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELK 382
K+ + ++ + + +R+QER ++ + + RE++ +L E+ +R ++E + + E+EL+
Sbjct: 678 KRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQE---RLQAERELQ 734
Query: 383 EKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKA 440
E+E+ + +K++ ++ L+E+++KE Q+ L E + ++E+EK+ +E KA
Sbjct: 735 EREKALRLQKEQLQR----ELEEKKKKEEQQRL---AERQLQEEQEKKAKEAAGASKA 785
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 71.6 bits (174), Expect = 3e-12
Identities = 36/111 (32%), Positives = 78/111 (70%), Gaps = 4/111 (3%)
Query: 332 KNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKRE 391
K + ++ R +ERL +Q RE++EK++ + KR +E+ K+ +E+EKEL+E+++ ++E
Sbjct: 252 KQEEKMWRQEERLREQEGKM--REQEEKMRRQEKRLREQEKELREQEKELREQKKLREQE 309
Query: 392 KDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEK 442
+ +E+ EK +EE+ +E++E + +E+R E+EK++RE+E++++ ++
Sbjct: 310 EQMQEQEEKMWEQEEKMREQEEKMWR--QEERLWEQEKQMREQEQKMRDQE 358
Score = 69.3 bits (168), Expect = 2e-11
Identities = 40/115 (34%), Positives = 77/115 (66%), Gaps = 10/115 (8%)
Query: 336 RLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEK 395
RL+ +ER+ +Q K+ +++EK++EE K+ +E+ KK ++E++++E+ER +REK +
Sbjct: 515 RLREKEERMREQKKMW---QQEEKMREE-KKTQEQEKKTWDQEEKMREEERMREREKKMR 570
Query: 396 EKAEKQRLKEERRKERQEAL---EAKL---EEKRKKEEEKRLREEEKRIKAEKAE 444
E+ E R +EE+ +E++E + E K+ EEK +++EEK +EEK + E+ +
Sbjct: 571 EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEED 625
Score = 68.6 bits (166), Expect = 3e-11
Identities = 44/138 (31%), Positives = 84/138 (60%), Gaps = 22/138 (15%)
Query: 327 KGSTEKNKLRLQRDQERLGKQLKLRAERE----EKEKLKEEAKRAKEEAKKKKEEEKELK 382
+G + + +++R ++RL +Q K E+E E++KL+E+ ++ +E+ +K E+E++++
Sbjct: 268 EGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMR 327
Query: 383 EKE----RREKR----EKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKE-------- 426
E+E R+E+R EK +E+ +K R +EER E+ E L K E R++E
Sbjct: 328 EQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEK 387
Query: 427 --EEKRLREEEKRIKAEK 442
EE+R+RE EK+++ E+
Sbjct: 388 MQEEERIREREKKMREEE 405
Score = 67.8 bits (164), Expect = 5e-11
Identities = 76/359 (21%), Positives = 160/359 (44%), Gaps = 39/359 (10%)
Query: 324 KFVKGSTEKNKLR--LQRDQERLGKQLKLRAEREEK-----EKLKEEAKRAKEEAKKKKE 376
KF+ + N L+ + R +E L +Q K ++EEK E+L+E+ + +E+ +K +
Sbjct: 221 KFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRR 280
Query: 377 EEKELKEKERREKREKDEKEKAEKQRLKE-ERRKERQEALEAKLEEKRKKEEEKRLREEE 435
+EK L+E+E+ E RE+ EKE E+++L+E E + + QE + EEK +++EEK R+EE
Sbjct: 281 QEKRLREQEK-ELREQ-EKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE 338
Query: 436 KRIKAEKAEITRFFQKPKTPQAPKTLAGSCGKFAPFEIKEHMVLAPRRRTAFHPDLCSQL 495
+ + EK ++ QK + + ++ + R + Q
Sbjct: 339 RLWEQEK-QMREQEQKMRDQE------------ERMWEQDERLREKEERMREQEKMWEQE 385
Query: 496 DQLLQQQSGEFSFLKDLKGRQPLRSGPTHVSTRNADIFNSDVVIVERGKGDGVPERR-KF 554
+++ +++ K + + +R + + +++ + + + +PE++ K
Sbjct: 386 EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE---EKEWQQQRLPEQKEKL 442
Query: 555 GRMKLLQFCENHRPAYWGTWNKKTALIRARDPWAQDTKLLDYE---VDSDEEWEEEEPGE 611
+ +Q E W ++ + + W Q+ K+ E D+ WE+EE
Sbjct: 443 WEQEKMQEQEEK------IWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 496
Query: 612 SLSHSEGDDDDDMGEDEDEDDGFFVPHGYLSEDEGVTEECADPENHKVRQKLKAKEWDE 670
D ++ M E +D+ + E + + ++ K Q+ + K WD+
Sbjct: 497 DQEQKMWDQEERMWE---QDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQ 552
Score = 65.1 bits (157), Expect = 3e-10
Identities = 34/103 (33%), Positives = 73/103 (70%), Gaps = 4/103 (3%)
Query: 336 RLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEK 395
++Q +E++ +Q + E+EE++K++E+ + E+ +K +E+E+++ E+E + RE++EK
Sbjct: 603 KMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK-MREQEEK 661
Query: 396 --EKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEK 436
E+ EK + +EE+ +E++E ++ + EEK +++EEK +EEK
Sbjct: 662 MREQEEKMQGQEEKMREQEEKMQGQ-EEKMREQEEKMRGQEEK 703
Score = 63.9 bits (154), Expect = 7e-10
Identities = 37/120 (30%), Positives = 79/120 (65%), Gaps = 13/120 (10%)
Query: 332 KNKLRLQRDQ-----ERLGKQLKLRAEREEK-----EKLKEEAKRAKEEAKKKKEEEKEL 381
+ K+R Q DQ E++ Q + ++EE+ E+L+E+ +R +E+ K ++EEK
Sbjct: 478 QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMR 537
Query: 382 KEKERREKREK--DEKEK-AEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRI 438
+EK+ +E+ +K D++EK E++R++E +K R+E + +E++ +E+E+++RE+E+++
Sbjct: 538 EEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKM 597
Score = 63.5 bits (153), Expect = 9e-10
Identities = 38/132 (28%), Positives = 81/132 (61%), Gaps = 8/132 (6%)
Query: 319 RRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEE 378
++I K+ K ++ +LR Q + R ++ R E+ +E+ KE ++ KE ++KK E
Sbjct: 248 KKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLRE 307
Query: 379 KELKEKERREK--------REKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKR 430
+E + +E+ EK RE++EK +++RL E+ ++ R++ + + +E+R E+++R
Sbjct: 308 QEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDER 367
Query: 431 LREEEKRIKAEK 442
LRE+E+R++ ++
Sbjct: 368 LREKEERMREQE 379
Score = 63.2 bits (152), Expect = 1e-09
Identities = 35/123 (28%), Positives = 80/123 (65%), Gaps = 13/123 (10%)
Query: 336 RLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKER------REK 389
++Q +E++ +Q + E+EEK + +EE +EE ++EEE +++E+E +
Sbjct: 582 KMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKM 641
Query: 390 REKDEK--EKAEKQRLKEERRKERQEALEAKLEEKRKKEE-----EKRLREEEKRIKAEK 442
+E++EK E+ EK R +EE+ +E++E ++ + E+ R++EE E+++RE+E++++ ++
Sbjct: 642 QEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQE 701
Query: 443 AEI 445
++
Sbjct: 702 EKM 704
Score = 62.8 bits (151), Expect = 1e-09
Identities = 31/126 (24%), Positives = 80/126 (63%), Gaps = 11/126 (8%)
Query: 331 EKNKLRLQRD----QERLGKQLKLRAER----EEKEKLKEEAKRAKEEAKKKKEEEKELK 382
++ K+R Q + ++++ +Q K+R + E++EK++++ ++ ++ ++ E+++ L+
Sbjct: 458 QEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLR 517
Query: 383 EKERREKREK---DEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIK 439
EKE R + +K ++EK +++ +E+ K+ + E EE+R +E EK++REEE+ ++
Sbjct: 518 EKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMR 577
Query: 440 AEKAEI 445
++ ++
Sbjct: 578 EQEEKM 583
Score = 62.8 bits (151), Expect = 1e-09
Identities = 39/141 (27%), Positives = 84/141 (59%), Gaps = 7/141 (4%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKR 390
++ K+ Q +++++ +Q ++ E+EEK + +EE K ++E K +++EEK +++E+ + +
Sbjct: 614 QEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEE-KMWEQEEKMREQEEKMREQEEKMQGQ 672
Query: 391 EKDEKEKAEKQRLKEERRKERQEAL---EAKL---EEKRKKEEEKRLREEEKRIKAEKAE 444
E+ +E+ EK + +EE+ +E++E + E K+ EEK +EEK +EE R K E+
Sbjct: 673 EEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIR 732
Query: 445 ITRFFQKPKTPQAPKTLAGSC 465
+ + + P+ + + C
Sbjct: 733 DQKEKMQERLPEHEERCSEPC 753
Score = 62.0 bits (149), Expect = 3e-09
Identities = 33/121 (27%), Positives = 80/121 (66%), Gaps = 15/121 (12%)
Query: 339 RDQERLG-KQLKLRAE----REEKEKLKEEAKRAKEEAKKKKEEEKELKEKERR------ 387
R++ER+ ++ K+R E RE++EK++E+ ++ +E+ +K E+E++++E+E +
Sbjct: 557 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 616
Query: 388 ---EKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAE 444
E+ E+D+ ++ E+ ++E + + QE + EEK +++EEK +RE+E++++ ++ +
Sbjct: 617 KMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEK-MREQEEKMQGQEEK 675
Query: 445 I 445
+
Sbjct: 676 M 676
Score = 60.8 bits (146), Expect = 6e-09
Identities = 32/113 (28%), Positives = 77/113 (68%), Gaps = 7/113 (6%)
Query: 339 RDQERLGKQLKLRAEREEK----EKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDE 394
R++++ +Q K ++EEK E+++E K+ +EE + +E+E++++E+E + RE++E
Sbjct: 537 REEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEK-MREQEE 595
Query: 395 K--EKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEI 445
K E+ EK + +EE+ E++E + + EE + +E+E+ + E+E++++ ++ ++
Sbjct: 596 KMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKM 648
Score = 60.5 bits (145), Expect = 7e-09
Identities = 33/117 (28%), Positives = 75/117 (64%), Gaps = 8/117 (6%)
Query: 336 RLQRDQERLGKQLKLRAEREEK-----EKLKEEAKRAKEEAKKKKEEEKELKEKERREKR 390
+++ ++E + +Q + E+EEK EK+ E+ ++ +E+ +K E+E+++ E+E +K
Sbjct: 568 KMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKM 627
Query: 391 EKDEK---EKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAE 444
++ E+ E+ EK + +EE+ E++E + + E+ R++EE+ + +EE+ R + EK +
Sbjct: 628 QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQ 684
Score = 60.1 bits (144), Expect = 1e-08
Identities = 37/112 (33%), Positives = 67/112 (59%), Gaps = 17/112 (15%)
Query: 347 QLKLRAEREEKEKLK---EEAKRAKEEAK-------------KKKEEEKELKEKERREKR 390
Q KLR EK +++ +E KR E AK + +E+EL+E+E++ R
Sbjct: 193 QEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKK-IR 251
Query: 391 EKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEK 442
+++EK +++RL+E+ K R++ + + +EKR +E+EK LRE+EK ++ +K
Sbjct: 252 KQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQK 303
Score = 58.5 bits (140), Expect = 3e-08
Identities = 34/123 (27%), Positives = 76/123 (61%), Gaps = 12/123 (9%)
Query: 332 KNKLRLQRDQERLGKQLKLRAE---REEKEKLKEEAKRAKEEAKKKKEEEKELKEKERR- 387
+ K +++++ ++ K+R E RE ++K++EE + +E+ +K +E+E++++E+E +
Sbjct: 538 EEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKM 597
Query: 388 ---EKREKDEKEKAEKQRLK-----EERRKERQEALEAKLEEKRKKEEEKRLREEEKRIK 439
E++ ++++EK +Q K EE + + QE + + EEK +++EEK +EEK +
Sbjct: 598 WEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMRE 657
Query: 440 AEK 442
E+
Sbjct: 658 QEE 660
Score = 53.1 bits (126), Expect = 1e-06
Identities = 32/125 (25%), Positives = 81/125 (64%), Gaps = 15/125 (12%)
Query: 331 EKNKL----RLQRDQERLGKQLKLRAEREE---KEKLKEEAKRAKEEAKKKKEEEKELKE 383
+K KL ++Q +E++ +Q + ++EE +EK ++ +E+ + E+E+++++
Sbjct: 438 QKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRD 497
Query: 384 KERR----EKR--EKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKR 437
+E++ E+R E+DE+ + +++R++E+++ +QE E EEK+ +E+EK+ ++E++
Sbjct: 498 QEQKMWDQEERMWEQDERLREKEERMREQKKMWQQE--EKMREEKKTQEQEKKTWDQEEK 555
Query: 438 IKAEK 442
++ E+
Sbjct: 556 MREEE 560
Score = 40.8 bits (94), Expect = 0.006
Identities = 64/282 (22%), Positives = 124/282 (43%), Gaps = 38/282 (13%)
Query: 358 EKLKEEAKRAKEEAKKKKEEEKELKEK--ERREKREKDEKEKAEKQ-RLKEERRK-ERQE 413
E+L +E E + +ELK+K E +EK E EK+E Q +KE +RK ER +
Sbjct: 162 EELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAK 221
Query: 414 ALEAKLEEKRKKEE----EKRLREEEKRIKAEKAEITRFFQKPKTPQAPKTLAGSCGKFA 469
L +++ +EE E+ LRE+EK+I+ ++ ++ R ++ + + GK
Sbjct: 222 FLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQE---------GKMR 272
Query: 470 PFEIKEHMVLAPRRRTAFHPDLCSQLDQLLQQQSGEFSFLKDLKGRQPLRSGPTHVSTRN 529
E +E M +R L Q +L +Q+ K+L+ ++ LR + +
Sbjct: 273 --EQEEKMRRQEKR-------LREQEKELREQE-------KELREQKKLREQEEQMQEQE 316
Query: 530 ADIFNSDVVIVERGKGDGVPERRKFGRMKLLQFCENH-RPAYWGTWNKKTALIRARDPWA 588
++ + + E+ + E R + + K ++ E R W + L +
Sbjct: 317 EKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMR 376
Query: 589 QDTKLLDYEVDSDEEWEEEEPGESLSHSEGDDDDDMGEDEDE 630
+ K+ + E E+ +EEE ++++ M E E++
Sbjct: 377 EQEKMWEQE----EKMQEEERIREREKKMREEEETMREQEEK 414
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 71.6 bits (174), Expect = 3e-12
Identities = 55/223 (24%), Positives = 108/223 (48%), Gaps = 42/223 (18%)
Query: 251 PQIKSLPATPQGKNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPKQH--SS 308
P S+ P GK SF +E SH L P + + PP P +Q
Sbjct: 380 PAQPSVAKVPYGKG--------PSFNQERGTSSH--LPPPPKLLAQQHPP-PDRQAVPGR 428
Query: 309 TSPFPTSTPL---------RRITKKFVKGSTEKNKLRLQRDQERLGKQLKLR-------- 351
PFP+ + RR + + + E+ + R + ++ R+ +Q K
Sbjct: 429 PGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRL 488
Query: 352 -----------AEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEK 400
+ E +E+ +E+ + ++E +K++E+E+E + ++ RE++++ EKE ++
Sbjct: 489 DEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKE 548
Query: 401 QRLKEERRKERQEALEAKLEEKRKKEEE-KRLREEEKRIKAEK 442
Q + E KER++ E +LE +++KE+E ++++E+EK + EK
Sbjct: 549 QEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEK 591
Score = 63.2 bits (152), Expect = 1e-09
Identities = 42/121 (34%), Positives = 70/121 (57%), Gaps = 3/121 (2%)
Query: 338 QRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEK 397
+R++E+ ++ K + +E+E+ KE K + + +K+KE EKE +++ EK K EKEK
Sbjct: 506 EREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEK 565
Query: 398 A-EKQRLKE-ERRKERQEALEAKLEEKRKKEEEK-RLREEEKRIKAEKAEITRFFQKPKT 454
E+Q+ KE E +K +++ E +LE++R+K EEK RE EK E K +
Sbjct: 566 ELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEE 625
Query: 455 P 455
P
Sbjct: 626 P 626
Score = 54.3 bits (129), Expect = 5e-07
Identities = 52/184 (28%), Positives = 98/184 (53%), Gaps = 16/184 (8%)
Query: 327 KGSTEKNKLRLQRDQERLGKQLKLRAEREEKEK-LKEEAKRAKE---EAKKKKEEEKEL- 381
K + +L +++QER ++ K R ++EKEK L++E ++ +E E K++KE+E E
Sbjct: 511 KEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQ 570
Query: 382 --KEKERREKREKDEKEKAEKQRLK-EERRKERQEALEAKLEEKRKKEEEKRLREEEKRI 438
KEKE ++ +E++++ + EK+R K EE+ + R+ LE +E K+E E +EE+ +
Sbjct: 571 KEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVE---KQESENSCNKEEEPV 627
Query: 439 KAEKAEITRFFQKPKTPQAPKTLAGSCGKFAPFEIKEHMVLAPRRRTAFHPDLCSQLDQL 498
+ + +K TP +T S + P + + + + + P Q +Q+
Sbjct: 628 FTR--QDSNRSEKEATPVVHETEPESGSQPRPAVLSGYF---KQFQKSLPPRFQRQQEQM 682
Query: 499 LQQQ 502
QQQ
Sbjct: 683 KQQQ 686
Score = 30.8 bits (68), Expect = 6.3
Identities = 27/109 (24%), Positives = 46/109 (42%), Gaps = 4/109 (3%)
Query: 353 EREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQ 412
ER E EK K+E E K ++ K E + + +E+ + ++ ++
Sbjct: 961 ERPE-EKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKP 1019
Query: 413 EALEAKLEEKRKKEEEKRLRE---EEKRIKAEKAEITRFFQKPKTPQAP 458
+ K E +++KE+E E E+ +K EK E P PQ P
Sbjct: 1020 VLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPP 1068
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 71.6 bits (174), Expect = 3e-12
Identities = 45/115 (39%), Positives = 74/115 (64%), Gaps = 9/115 (7%)
Query: 338 QRDQERLGKQLKLRAEREE-KEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKE 396
Q +QER+ K+ + R EREE K K +EE R +EEA+K++EE K +++E ++K+E +EK
Sbjct: 417 QEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERK--RQEEEKKKQEGEEKR 474
Query: 397 KA--EKQRLKEE----RRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEI 445
KA E +R EE + K+ QE E + EK+K+ E + RE ++++ E+ +I
Sbjct: 475 KAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMRLEREQI 529
Score = 67.4 bits (163), Expect = 6e-11
Identities = 42/105 (40%), Positives = 71/105 (67%), Gaps = 10/105 (9%)
Query: 346 KQLKLRAEREEKEKL-KEEAKRA-KEEAKKKKEEEK-ELKEKERREKREKDEKEKAEKQR 402
+Q +L+ E+EE+E++ KEE R +EE K+K EEE+ L+E+ R+++ E+ +E+ +K++
Sbjct: 409 RQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQ 468
Query: 403 LKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITR 447
EE+RK +EA KRK EEE L+E++++ K EKA I +
Sbjct: 469 EGEEKRKAGEEA-------KRKAEEELLLKEKQEQEKQEKAMIEK 506
Score = 65.1 bits (157), Expect = 3e-10
Identities = 39/131 (29%), Positives = 76/131 (58%), Gaps = 3/131 (2%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKR 390
E+ +L+ + ++ERL + + R + EE+++ +EE K+ + E K+K EE + K +E +
Sbjct: 432 EREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLK 491
Query: 391 EKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKA--EITRF 448
EK E+EK EK +++++ +A E E+ R + E+ L+ E++R++ +K EI +
Sbjct: 492 EKQEQEKQEKAMIEKQKEAAETKAREV-AEQMRLEREQIMLQIEQERLERKKRIDEIMKR 550
Query: 449 FQKPKTPQAPK 459
+K P K
Sbjct: 551 TRKSDVPPQVK 561
Score = 61.2 bits (147), Expect = 4e-09
Identities = 41/143 (28%), Positives = 80/143 (55%), Gaps = 19/143 (13%)
Query: 320 RITKKFVKGSTEKNKLRL------QRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEA-- 371
R+ ++ +K E+ +LRL Q ++ + ++ K + E EEK K EEAKR EE
Sbjct: 430 RLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELL 489
Query: 372 -KKKKEEEKELKE--KERREKREKDEKEKAEKQRLK--------EERRKERQEALEAKLE 420
K+K+E+EK+ K ++++E E +E AE+ RL+ E+ R ER++ ++ ++
Sbjct: 490 LKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMRLEREQIMLQIEQERLERKKRIDEIMK 549
Query: 421 EKRKKEEEKRLREEEKRIKAEKA 443
RK + ++++E+ ++ + A
Sbjct: 550 RTRKSDVPPQVKKEDPKVGVQPA 572
Score = 60.1 bits (144), Expect = 1e-08
Identities = 35/100 (35%), Positives = 59/100 (59%), Gaps = 1/100 (1%)
Query: 344 LGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEK-ELKEKERREKREKDEKEKAEKQR 402
LGK + E K+ E +R K+++E+E+ E +E++R E+ E K + E+ R
Sbjct: 387 LGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLR 446
Query: 403 LKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEK 442
L+EE RK+ +E + E+K+++ EEKR EE + KAE+
Sbjct: 447 LEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEE 486
Score = 55.5 bits (132), Expect = 2e-07
Identities = 53/186 (28%), Positives = 83/186 (44%), Gaps = 31/186 (16%)
Query: 288 SSPS-STSSPEGPPAPPKQHSSTSPFPTSTPLRRIT----KKFVKGSTEKNKLRLQRD-- 340
SSP S ++ + P PK ++ P+P S R+ + K EK K +R+
Sbjct: 289 SSPVISKTATKAYPQSPK--TTKPPYPGSPVKYRLPALSGQDMPKRKAEKEKSNKEREGT 346
Query: 341 --QERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKK---------------EEEKELKE 383
Q+ G Q + E+ +K E A K + E K L E
Sbjct: 347 LAQQAAGPQGEEALEKHVVDKHASEKHAAAAGGKAENSAALGKPTAGTTDAGEAAKILAE 406
Query: 384 KER-----REKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRI 438
K R +E+ E++ EK E+ RL+ E K + E +LEE+ +K+EE+R R+EE++
Sbjct: 407 KRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKK 466
Query: 439 KAEKAE 444
K E E
Sbjct: 467 KQEGEE 472
Score = 48.9 bits (115), Expect = 2e-05
Identities = 30/86 (34%), Positives = 56/86 (65%), Gaps = 8/86 (9%)
Query: 355 EEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEA 414
+E+++L +E + +E+ +E++ K+K R + EK +E+ K L+E+R++E Q+
Sbjct: 52 DERQRLAKERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRK--LEEQRQREDQK- 108
Query: 415 LEAKLEEKRKKEEEKRLREEEKRIKA 440
A +EEKRK+ +LREEE+R++A
Sbjct: 109 -RAAVEEKRKQ----KLREEEERLEA 129
Score = 48.5 bits (114), Expect = 3e-05
Identities = 29/77 (37%), Positives = 47/77 (61%), Gaps = 4/77 (5%)
Query: 375 KEEEKELKEKERREKREK----DEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKR 430
K +E++ KERRE+REK E++ EKQ+ + +++ E KLEE+R++E++KR
Sbjct: 50 KSDERQRLAKERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQREDQKR 109
Query: 431 LREEEKRIKAEKAEITR 447
EEKR + + E R
Sbjct: 110 AAVEEKRKQKLREEEER 126
Score = 45.4 bits (106), Expect = 2e-04
Identities = 32/100 (32%), Positives = 61/100 (61%), Gaps = 16/100 (16%)
Query: 340 DQERLGKQLKLRAEREEKEK--------LKEEAKRAKEEAKKKKEEE-KELKEKERREKR 390
+++RL K+ REE+EK + E+ KRA+ + +K+ EE ++L+E+ +RE +
Sbjct: 53 ERQRLAKE-----RREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQREDQ 107
Query: 391 EKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKR 430
++ E+ KQ+L+EE +ER EA+ + E+ ++ E K+
Sbjct: 108 KRAAVEEKRKQKLREE--EERLEAMMRRSLERTQQLELKK 145
Score = 42.0 bits (97), Expect = 0.003
Identities = 27/83 (32%), Positives = 47/83 (56%), Gaps = 4/83 (4%)
Query: 364 AKRAKEEAKKKKEEEKELKEKER----REKREKDEKEKAEKQRLKEERRKERQEALEAKL 419
A R + + + E LK ER +E+RE+ EK A +++ E++K + E ++
Sbjct: 32 AVRTSQPNYRPQGMEGFLKSDERQRLAKERREEREKCLAAREQQILEKQKRARLQYEKQM 91
Query: 420 EEKRKKEEEKRLREEEKRIKAEK 442
EE+ +K EE+R RE++KR E+
Sbjct: 92 EERWRKLEEQRQREDQKRAAVEE 114
Score = 40.4 bits (93), Expect = 0.008
Identities = 33/109 (30%), Positives = 63/109 (57%), Gaps = 16/109 (14%)
Query: 329 STEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEE-KELKEKERR 387
S E+ +L +R +ER K A RE++ + E+ KRA+ + +K+ EE ++L+E+ +R
Sbjct: 51 SDERQRLAKERREERE----KCLAAREQQ--ILEKQKRARLQYEKQMEERWRKLEEQRQR 104
Query: 388 E--KREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREE 434
E KR E+++ +K R +EER LEA + ++ ++ L+++
Sbjct: 105 EDQKRAAVEEKRKQKLREEEER-------LEAMMRRSLERTQQLELKKK 146
Score = 31.2 bits (69), Expect = 4.8
Identities = 22/65 (33%), Positives = 38/65 (58%), Gaps = 10/65 (15%)
Query: 399 EKQRLKEERRKERQEALEAKLE---EKRK-------KEEEKRLREEEKRIKAEKAEITRF 448
E+QRL +ERR+ER++ L A+ + EK+K K+ E+R R+ E++ + E +
Sbjct: 53 ERQRLAKERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQREDQKRAAV 112
Query: 449 FQKPK 453
+K K
Sbjct: 113 EEKRK 117
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 70.5 bits (171), Expect = 7e-12
Identities = 84/425 (19%), Positives = 191/425 (44%), Gaps = 54/425 (12%)
Query: 332 KNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKRE 391
K + ++ R +ERL +Q RE++EK+ + KR +E+ K+ +E+EKEL+E++ ++E
Sbjct: 290 KQEEKMWRQEERLREQEGKM--REQEEKMWRQEKRLREQEKELREQEKELREQKELREQE 347
Query: 392 KDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEI----TR 447
+ +E+ EK +EE+ +E++E + +E+R E+EK++RE+E++++ ++ + R
Sbjct: 348 EQMQEQEEKMWEQEEKMREQEEKMWR--QEERLWEQEKQMREQEQKMRDQEERMWEQDER 405
Query: 448 FFQKPKTPQAPKTLAGSCGKFAPFEIKEHMVLAPRRRTAFHPDLCSQLDQLLQQQSGEFS 507
+K + + + + K +E + ++T + + +++ +++
Sbjct: 406 LREKEERMREQEKMWEQVEKMR----EEKKMQEQEKKTRDQEEKMQEEERIREREK---- 457
Query: 508 FLKDLKGRQPLRSGPTHVSTRNADIFNSDVVIVERGKGDGVPERR-KFGRMKLLQFCE-- 564
K + + +R + + +++ + + + +PE++ K + +Q E
Sbjct: 458 --KMREEEETMREQEEKMQKQEENMWEQE---EKEWQQQRLPEQKEKLWEQEKMQEQEEK 512
Query: 565 --------NHRPAYWG----TWNKKTALIRARDPWAQDTKLLDYEVDSDEEWEEEEPGES 612
+ WG W ++ + W Q+ K+ D E + W++EE E
Sbjct: 513 IWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE---QKMWDQEERMEK 569
Query: 613 LSHSEGDDDDDMGEDEDEDDGFFVPHGYLSEDEGVTEECADPENHKVRQKLKAKEWDEFL 672
+ + D E E++ + E+E E + E Q+ K +E +E +
Sbjct: 570 KTQEQEKKTWDQEEKMREEERMREREKKMREEE---EMMREQEEKMQEQEEKMQEQEEKM 626
Query: 673 AKGKRFRVLQPVKIGCVWAADRDCAGDDLKVLQQFAACFLETLPAQEE---QTPKASKRE 729
+ + Q K +W + + K+ +Q + LP Q+E + K ++E
Sbjct: 627 WEQEEKMQEQEEK---MWEQEEKMWEQEEKMWEQ------QRLPEQKEKLWEHEKMQEQE 677
Query: 730 RRDEQ 734
+ EQ
Sbjct: 678 KMQEQ 682
Score = 65.5 bits (158), Expect = 2e-10
Identities = 35/119 (29%), Positives = 83/119 (69%), Gaps = 8/119 (6%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAER--EEKEKLKEEAKRAKEEAKKKKEEEKELKEKERRE 388
++ +LR Q++ +Q++ + E+ E++EK++E+ ++ + ++ E+EK+++E+E++
Sbjct: 333 QEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK- 391
Query: 389 KREKDEK--EKAEKQRLKEERRKERQ---EALEAKLEEKRKKEEEKRLREEEKRIKAEK 442
R+++E+ E+ E+ R KEER +E++ E +E EEK+ +E+EK+ R++E++++ E+
Sbjct: 392 MRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEE 450
Score = 65.1 bits (157), Expect = 3e-10
Identities = 40/126 (31%), Positives = 77/126 (61%), Gaps = 8/126 (6%)
Query: 324 KFVKGSTEKNKLR--LQRDQERLGKQLKLRAEREEK-----EKLKEEAKRAKEEAKKKKE 376
KF+ + N L+ + R +E L +Q K ++EEK E+L+E+ + +E+ +K
Sbjct: 259 KFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWR 318
Query: 377 EEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEK 436
+EK L+E+E+ E RE++++ + +K+ ++E + + QE + EEK +++EEK R+EE+
Sbjct: 319 QEKRLREQEK-ELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER 377
Query: 437 RIKAEK 442
+ EK
Sbjct: 378 LWEQEK 383
Score = 62.0 bits (149), Expect = 3e-09
Identities = 39/127 (30%), Positives = 76/127 (59%), Gaps = 15/127 (11%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAE---REEKEKLKEEAKRAKEEAKKKKEEEKELKEKE-- 385
EK + + Q +++ Q K+R E RE ++K++EE + +E+ +K +E+E++++E+E
Sbjct: 690 EKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEE 749
Query: 386 ---RREKREKDEKEKAEKQRLKEERRK-------ERQEALEAKLEEKRKKEEEKRLREEE 435
+ EK + E++ E+QRL E++ K + QE + + E+ R +EE+ R +EE+
Sbjct: 750 MWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEK 809
Query: 436 KRIKAEK 442
R + EK
Sbjct: 810 MRGQEEK 816
Score = 60.1 bits (144), Expect = 1e-08
Identities = 34/106 (32%), Positives = 69/106 (65%), Gaps = 6/106 (5%)
Query: 336 RLQRDQERLGKQLKLRAE---REEKEKLKEEAKRAK--EEAKKKKEEEKELKEKERREKR 390
RL +E+L + K++ + +E++EK+ E+ K K +E +KK ++++++E+E +R
Sbjct: 659 RLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRER 718
Query: 391 EKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEK 436
EK +E+ E R +EE+ +E++E ++ + EE+ ++EEK +EEK
Sbjct: 719 EKKMREEEEMMREQEEKMQEQEEKMQEQ-EEEMWEQEEKMWEQEEK 763
Score = 59.3 bits (142), Expect = 2e-08
Identities = 39/119 (32%), Positives = 74/119 (62%), Gaps = 4/119 (3%)
Query: 339 RDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKA 398
R++ER+ ++ K E EE + +EE K ++E K +++EEK +++E+ +++E+ E+
Sbjct: 586 REEERMREREKKMREEEEMMREQEE-KMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQE 644
Query: 399 EKQRLKEERRKERQEALEAK--LEEKRKKEEEKRLREEEKRI-KAEKAEITRFFQKPKT 454
EK +EE+ E+Q E K L E K +E+++++E+E++I + EK E Q+ KT
Sbjct: 645 EKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKT 703
Score = 58.9 bits (141), Expect = 2e-08
Identities = 34/114 (29%), Positives = 74/114 (64%), Gaps = 6/114 (5%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKR 390
E + RL +E+L +Q K++ E++EK+ E+ ++ +++ + +E+K ++++ RE+
Sbjct: 487 EWQQQRLPEQKEKLWEQEKMQ---EQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ- 542
Query: 391 EKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKK--EEEKRLREEEKRIKAEK 442
E E+ EK R +E++ +++E +E K +E+ KK ++E+++REEE+ + EK
Sbjct: 543 EDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREK 596
Score = 58.2 bits (139), Expect = 4e-08
Identities = 30/133 (22%), Positives = 83/133 (62%), Gaps = 8/133 (6%)
Query: 336 RLQRDQERLGKQLKLRAERE---EKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREK 392
++ +E++ +Q +L ++E E EK++E+ K ++E K ++E+ E K +E+ EK+
Sbjct: 646 KMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQ-EKKTW 704
Query: 393 DEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEI----TRF 448
D+++ E++ ++E +K R+E + +E++ +E+E++++E+E+ + ++ ++ +
Sbjct: 705 DQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKM 764
Query: 449 FQKPKTPQAPKTL 461
+++ + P+ + L
Sbjct: 765 WEQQRLPEQKEKL 777
Score = 57.8 bits (138), Expect = 5e-08
Identities = 29/119 (24%), Positives = 74/119 (62%), Gaps = 9/119 (7%)
Query: 336 RLQRDQERLGKQLKLRAEREEK----EKLKEEAKRAKE-----EAKKKKEEEKELKEKER 386
++Q +E++ +Q + E+EEK ++L E+ ++ E E +K +E+E+++ E+E+
Sbjct: 632 KMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEK 691
Query: 387 REKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEI 445
EK+ +++++K Q E R+ + + EE+ +E+E++++E+E++++ ++ E+
Sbjct: 692 MEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEM 750
Score = 57.4 bits (137), Expect = 6e-08
Identities = 35/127 (27%), Positives = 79/127 (62%), Gaps = 15/127 (11%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEK-----EKLKEEAKRAKE-----EAKKKKEEEKE 380
++ + ++Q +E++ +Q + E+EEK EK+ E+ ++ E E K+K E ++
Sbjct: 613 QEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEK 672
Query: 381 LKEKERREKREKD--EKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRI 438
++E+E+ +++E+ E+EK EK+ ++E++ QE + EE+ +E EK++REEE+ +
Sbjct: 673 MQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMR---EEESMREREKKMREEEEMM 729
Query: 439 KAEKAEI 445
+ ++ ++
Sbjct: 730 REQEEKM 736
Score = 56.6 bits (135), Expect = 1e-07
Identities = 35/123 (28%), Positives = 74/123 (60%), Gaps = 12/123 (9%)
Query: 321 ITKKFVKGSTEKNKLRLQ-RDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEK 379
+ +K +EK++++L ++ +R ++ K + + L+EE R +E+
Sbjct: 230 LQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWR----------QEE 279
Query: 380 ELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIK 439
EL+E+E++ R+++EK +++RL+E+ K R++ + +EKR +E+EK LRE+EK ++
Sbjct: 280 ELREQEKK-IRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELR 338
Query: 440 AEK 442
+K
Sbjct: 339 EQK 341
Score = 56.6 bits (135), Expect = 1e-07
Identities = 33/116 (28%), Positives = 70/116 (60%), Gaps = 6/116 (5%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKR 390
E+ K++ Q +E++ +Q K+ + +E+EK + ++ +EE ++ E+K +E+E ++
Sbjct: 675 EQEKMQEQ--EEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQ 732
Query: 391 EKDEKEKAEKQRLKEERRKERQEAL----EAKLEEKRKKEEEKRLREEEKRIKAEK 442
E+ +E+ EK + +EE E++E + E E++R E++++L E EK + EK
Sbjct: 733 EEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEK 788
Score = 56.2 bits (134), Expect = 1e-07
Identities = 31/131 (23%), Positives = 80/131 (61%), Gaps = 5/131 (3%)
Query: 320 RITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAE---REEKEKLKEEAKRAKEEAKKKKE 376
++ K +K E+ K L + Q ++ R E RE+++K++++ ++ + ++ +E
Sbjct: 245 QLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLRE 304
Query: 377 EEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEK 436
+E +++E+E EK + EK E+++ E+ KE +E E + +E++ +E+E+++ E+E+
Sbjct: 305 QEGKMREQE--EKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEE 362
Query: 437 RIKAEKAEITR 447
+++ ++ ++ R
Sbjct: 363 KMREQEEKMWR 373
Score = 55.1 bits (131), Expect = 3e-07
Identities = 37/118 (31%), Positives = 72/118 (61%), Gaps = 6/118 (5%)
Query: 326 VKGSTEKNKLRLQ----RDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEK-E 380
V+ E+ K++ Q RDQE ++ + ERE+K + +EE R +EE +K+EE E
Sbjct: 423 VEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE 482
Query: 381 LKEKERREKREKDEKEKA-EKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKR 437
+EKE +++R ++KEK E+++++E+ K ++ + + +E+ +E+K R+E+ R
Sbjct: 483 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR 540
Score = 54.3 bits (129), Expect = 5e-07
Identities = 35/123 (28%), Positives = 71/123 (57%), Gaps = 17/123 (13%)
Query: 337 LQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEK--ELKEKERREKREKDE 394
+ R+QE ++ + + + +E++ ++E K ++E K ++EEK E +EK ++R ++
Sbjct: 604 MMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQ 663
Query: 395 KEK-------AEKQRLKEERRK-ERQEALEAKLEEKRKK-------EEEKRLREEEKRIK 439
KEK E+++++E+ K QE +E K +E+ KK EE+ +RE EK+++
Sbjct: 664 KEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMR 723
Query: 440 AEK 442
E+
Sbjct: 724 EEE 726
Score = 53.5 bits (127), Expect = 9e-07
Identities = 33/108 (30%), Positives = 68/108 (62%), Gaps = 5/108 (4%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKR 390
++ K+R Q +Q+ ++ ++ + +E+EK + + E ++ +E EK+++E+E R
Sbjct: 549 QEEKMRDQ-EQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM-MR 606
Query: 391 EKDEK--EKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEK 436
E++EK E+ EK + +EE+ E++E ++ + EEK ++EEK +EEK
Sbjct: 607 EQEEKMQEQEEKMQEQEEKMWEQEEKMQEQ-EEKMWEQEEKMWEQEEK 653
Score = 53.5 bits (127), Expect = 9e-07
Identities = 35/142 (24%), Positives = 79/142 (55%), Gaps = 14/142 (9%)
Query: 336 RLQRDQERLGKQLKLRAERE---EKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREK 392
++ +E++ +Q +L ++E E EK++E+ K ++E K + +EEK ++E+ +E+
Sbjct: 756 KMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEE 815
Query: 393 DEKEKAEKQRLKEER----------RKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEK 442
+ + EK +EE+ ++E+ E K+EEK + +EEK +RE+E++++ ++
Sbjct: 816 KMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEK-MREQEEKMRGQE 874
Query: 443 AEITRFFQKPKTPQAPKTLAGS 464
++ +K + + GS
Sbjct: 875 EKMREQEEKMRGQEEKIYCVGS 896
Score = 53.1 bits (126), Expect = 1e-06
Identities = 34/126 (26%), Positives = 75/126 (59%), Gaps = 16/126 (12%)
Query: 336 RLQRDQERLGKQLKLRAEREEKEK-------LKEEAKRAKEEAKKKKEEE--KELKEK-- 384
++Q +E++ +Q K+ + +E+EK ++EE + E K ++EEE +E +EK
Sbjct: 678 KMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQ 737
Query: 385 ---ERREKREKDEKEKAEKQRLKEERRKERQEALE--AKLEEKRKKEEEKRLREEEKRIK 439
E+ +++E++ E+ EK +EE+ E+Q E KL E K +E++++ E+E++++
Sbjct: 738 EQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMR 797
Query: 440 AEKAEI 445
++ ++
Sbjct: 798 DQEEKM 803
Score = 52.8 bits (125), Expect = 2e-06
Identities = 32/122 (26%), Positives = 76/122 (62%), Gaps = 12/122 (9%)
Query: 331 EKNKL----RLQRDQERLGKQLKLRAEREE---KEKLKEEAKRAKEEAKKKKEEEKELKE 383
+K KL ++Q +E++ +Q + ++EE +EK ++ +E+ + E+E+++++
Sbjct: 496 QKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRD 555
Query: 384 KERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKA 443
+E++ D++E+ EK+ ++E++ QE E EE+R +E EK++REEE+ ++ ++
Sbjct: 556 ---QEQKMWDQEERMEKKTQEQEKKTWDQE--EKMREEERMREREKKMREEEEMMREQEE 610
Query: 444 EI 445
++
Sbjct: 611 KM 612
Score = 50.4 bits (119), Expect = 8e-06
Identities = 41/140 (29%), Positives = 76/140 (54%), Gaps = 22/140 (15%)
Query: 318 LRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAE--REEKEKLKEEAKRAKE------ 369
+ + T++ K + ++ K+R + K+++ E RE++EK++E+ ++ +E
Sbjct: 692 MEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMW 751
Query: 370 --EAKKKKEEEK--------ELKEK-ERREKREKDEK--EKAEKQRLKEERRKERQEALE 416
E K ++EEK E KEK EK ++ EK E+ EK R +EE+ + ++E +
Sbjct: 752 EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMR 811
Query: 417 AKLEEKRKKEEEKRLREEEK 436
+ EEK + +EEK +EEK
Sbjct: 812 GQ-EEKMRGQEEKMWGQEEK 830
Score = 49.3 bits (116), Expect = 2e-05
Identities = 40/148 (27%), Positives = 77/148 (52%), Gaps = 5/148 (3%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKE---EAKKKKEEEKELKEKERR 387
++ + ++Q +E + +Q + E+EEK ++ KE E +K +E+EK +++E+
Sbjct: 737 QEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKM 796
Query: 388 EKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRI-KAEKAEIT 446
+E+ + + EK R +EE+ + ++E + + EEK +EEK +EEK + EK E
Sbjct: 797 RDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQ-EEKMWGQEEKMWGQEEKMWGQEEKMEEK 855
Query: 447 RFFQKPKTPQAPKTLAGSCGKFAPFEIK 474
Q+ K + + + G K E K
Sbjct: 856 MQGQEEKMREQEEKMRGQEEKMREQEEK 883
Score = 48.9 bits (115), Expect = 2e-05
Identities = 36/106 (33%), Positives = 66/106 (62%), Gaps = 7/106 (6%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKR 390
++ K+R Q ++ R G++ K+R + EEK + +EE +EE K +EEK ++E+ +
Sbjct: 792 QEEKMRDQEEKMR-GQEEKMRGQ-EEKMRGQEEKMWGQEE-KMWGQEEKMWGQEEKMWGQ 848
Query: 391 EKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEK 436
E+ +EK + Q EE+ +E++E + + EEK +++EEK +EEK
Sbjct: 849 EEKMEEKMQGQ---EEKMREQEEKMRGQ-EEKMREQEEKMRGQEEK 890
Score = 47.8 bits (112), Expect = 5e-05
Identities = 37/122 (30%), Positives = 74/122 (60%), Gaps = 12/122 (9%)
Query: 327 KGSTEKNKLRLQRDQERLGKQLKLRAE--REEKEKLKE-EAKRAKEEAKKKKEEEKELKE 383
K ++ K R Q ++ + ++++ R + REE+E ++E E K K+E ++EEKE ++
Sbjct: 431 KMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQ 490
Query: 384 KERREKREK-DEKEKAEKQRLK----EERRKERQE--ALEAKL--EEKRKKEEEKRLREE 434
+ E++EK E+EK ++Q K EE+ ++++E E K+ +EK +++E++ +E
Sbjct: 491 QRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE 550
Query: 435 EK 436
EK
Sbjct: 551 EK 552
Score = 45.8 bits (107), Expect = 2e-04
Identities = 30/107 (28%), Positives = 58/107 (54%), Gaps = 8/107 (7%)
Query: 347 QLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREK--REKDEKEKAEKQRLK 404
Q KL EK +++ K K + ++ K +++ +E+ R+++E + EK+ K
Sbjct: 231 QEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRK 290
Query: 405 EERRKERQEALEAKLEEKRKKEEEK------RLREEEKRIKAEKAEI 445
+E + RQE + E K +++EEK RLRE+EK ++ ++ E+
Sbjct: 291 QEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKEL 337
Score = 40.4 bits (93), Expect = 0.008
Identities = 42/148 (28%), Positives = 73/148 (49%), Gaps = 16/148 (10%)
Query: 316 TPLRRITKKFVKGSTEKNKLRLQRDQERLG---KQLKLRAEREEK-----EKLKEEAKRA 367
+PL ++ + G ++ RL G + L + R +K E+L +E
Sbjct: 150 SPLGCVSTSLIPGESKDLAGRLHHSWHFAGELQRALSAVSTRHKKADRYIEELTKERDAL 209
Query: 368 KEEAKKKKEEEKELKEK--ERREKREKDEKEKAEKQ-RLKEERRK-ERQEALEAKLEEKR 423
E + +ELK+K E +EK E EK+E Q +KE +RK ER + L +++
Sbjct: 210 SLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNT 269
Query: 424 KKEE----EKRLREEEKRIKAEKAEITR 447
+EE E+ LRE+EK+I+ ++ ++ R
Sbjct: 270 LQEEMWRQEEELREQEKKIRKQEEKMWR 297
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 70.5 bits (171), Expect = 7e-12
Identities = 71/251 (28%), Positives = 117/251 (46%), Gaps = 31/251 (12%)
Query: 235 GKVPM-VVLQDILAVRPPQIKSLPATPQGKNMTPESEVLESFPEEDSVLSHSSLSSPSST 293
G+VP VV Q L R +SL P K + +S ES E V + + P
Sbjct: 523 GQVPTPVVKQTKLKQRADSRESLK--PAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKV 580
Query: 294 SSPEG--------------PPAPPKQHSST---SPFPTSTPLRRITKKFVKGSTEKN--- 333
S E P K+ S SP ++ T K + EK
Sbjct: 581 ESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKK 640
Query: 334 --KLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKRE 391
K++ + +E K K A++E+K +K+E K KEE KK E +KE+K++E++E ++
Sbjct: 641 ETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKK--EVKKEIKKEEKKEPKK 698
Query: 392 KDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITR-FFQ 450
+ +KE K+ KE +++E++E K EEK K+E K+L ++ K+ +E +
Sbjct: 699 EVKKETPPKEVKKEVKKEEKKEV---KKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAAL 755
Query: 451 KPKTPQAPKTL 461
KPK P+ +++
Sbjct: 756 KPKVPKKEESV 766
Score = 57.4 bits (137), Expect = 6e-08
Identities = 79/357 (22%), Positives = 149/357 (41%), Gaps = 23/357 (6%)
Query: 117 IDLTEDSNEQPDSLVDHNKLNSEASPSREAINGQREDTGDQQGLLKAIQNDKLAFPGETL 176
+DL SL+ + N R G +GL K D L P T
Sbjct: 459 VDLPISYLTSVSSLIVWHPANPAEKIIRVLFPGNSTQYNILEGLEKLKHLDFLKQPLATQ 518
Query: 177 SDIPCKTEEEGVGCGGAGRRGDSQECSPRSCPELTSGPRMCPRKEQDSWSEAGGILFKGK 236
D+ + V +R DS+E + L S + ++ ++ E + K
Sbjct: 519 KDLTGQVPTPVVKQTKLKQRADSRESLKPAAKPLPS--KSVRKESKEETPEVTKVNHVEK 576
Query: 237 VPMVVLQDILAVRPPQIKSLPATPQGKNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSP 296
P V ++ + V+ K P + K E EV EE S + ++ P
Sbjct: 577 PPKVESKEKVMVK----KDKPIKTETKPSVTEKEVPSK--EEPSPVKAEVAEKQATDVKP 630
Query: 297 EGPPAPP-KQHSSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAERE 355
+ K+ + P + K+ K +++K ++++++ +++K ++E
Sbjct: 631 KAAKEKTVKKETKVKPEDKKEEKEKPKKEVAK---KEDKTPIKKEEKPKKEEVKKEVKKE 687
Query: 356 EKEKLKEEAKRAKEEAKKK---KEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQ 412
K KEE K K+E KK+ KE +KE+K++E++E ++++++ K E ++L ++ +K
Sbjct: 688 IK---KEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSST 744
Query: 413 EALEAK----LEEKRKKEEEKRLREEEKRIK-AEKAEITRFFQKPKTPQAPKTLAGS 464
EAK L+ K K+EE ++ K EK +I ++ K +A G+
Sbjct: 745 PLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKEGKAAEAVAAAVGT 801
Score = 47.8 bits (112), Expect = 5e-05
Identities = 58/190 (30%), Positives = 87/190 (45%), Gaps = 23/190 (12%)
Query: 296 PEGPPAPPK--QHSSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAE 353
P P P K + S P T + + K S K K+ +++D K +K +
Sbjct: 547 PAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVES--KEKVMVKKD-----KPIKTETK 599
Query: 354 REEKEK---LKEEAKRAKEEAKKKKEEEKELKEKERREKREKDE-KEKAE-KQRLKEERR 408
EK KEE K E +K + ++K K +EK K E K K E K+ KE+ +
Sbjct: 600 PSVTEKEVPSKEEPSPVKAEVAEK--QATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPK 657
Query: 409 KE---RQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITRFFQKPKTPQAPKTLAGSC 465
KE +++ K EEK KKEE K +E +K IK E+ + + K +TP PK +
Sbjct: 658 KEVAKKEDKTPIKKEEKPKKEEVK--KEVKKEIKKEEKKEPKKEVKKETP--PKEVKKEV 713
Query: 466 GKFAPFEIKE 475
K E+K+
Sbjct: 714 KKEEKKEVKK 723
Score = 34.3 bits (77), Expect = 0.57
Identities = 40/184 (21%), Positives = 64/184 (34%), Gaps = 22/184 (11%)
Query: 250 PPQIKSLPATPQGKNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSST 309
PP+ + P+ N+ E E E+ P + +V T PP P Q S
Sbjct: 2163 PPETEECPSITADANIDSEDES-ETIPTDKTV-----------TYKHMDPPPAPVQDRSP 2210
Query: 310 SPFPTSTPL---------RRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKL 360
SP + + + K K EK K + + + +K +++ + K
Sbjct: 2211 SPRHPDVSMVDPEALAIEQNLGKALKKDLKEKTKTKKPGTKTKSSSPVK-KSDGKSKPLA 2269
Query: 361 KEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLE 420
+E+ K K+KE EK K K EE+ KE + A A
Sbjct: 2270 ASPKPAGLKESSDKVSRVASPKKKESVEKAAKPTTTPEVKAARGEEKDKETKNAANASAS 2329
Query: 421 EKRK 424
+ K
Sbjct: 2330 KSAK 2333
Score = 32.3 bits (72), Expect = 2.2
Identities = 28/92 (30%), Positives = 38/92 (41%), Gaps = 1/92 (1%)
Query: 353 EREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQ 412
E EE E+ EE E+E+ K + REK E + R EE E
Sbjct: 950 EAEEPEEDGEEHVCVSASKHSPTEDEESAKAEADAYIREKRESVASGDDR-AEEDMDEAI 1008
Query: 413 EALEAKLEEKRKKEEEKRLREEEKRIKAEKAE 444
E EA+ E+ EE+K E+ + EK E
Sbjct: 1009 EKGEAEQSEEEADEEDKAEDAREEEYEPEKME 1040
Score = 31.6 bits (70), Expect = 3.7
Identities = 25/99 (25%), Positives = 42/99 (42%), Gaps = 9/99 (9%)
Query: 355 EEKEKLKEEAKRAKEEAKKKKE--EEKELKEKERREKREKDEKEKAEKQRLKEERRK--- 409
E E E K EEA++ +E EE + E +E KAE E+R+
Sbjct: 935 ESSETGDYEEKAETEEAEEPEEDGEEHVCVSASKHSPTEDEESAKAEADAYIREKRESVA 994
Query: 410 ----ERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAE 444
+E ++ +E+ ++ E+ EE+K A + E
Sbjct: 995 SGDDRAEEDMDEAIEKGEAEQSEEEADEEDKAEDAREEE 1033
Score = 30.8 bits (68), Expect = 6.3
Identities = 29/98 (29%), Positives = 47/98 (47%), Gaps = 11/98 (11%)
Query: 327 KGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAK---RAKEEA-----KKKKEEE 378
K TE+ + + +E + + E++E K EA R K E+ + +E+
Sbjct: 945 KAETEEAEEPEEDGEEHVCVSASKHSPTEDEESAKAEADAYIREKRESVASGDDRAEEDM 1004
Query: 379 KELKEKERREKREK--DEKEKAEKQRLKEERRKERQEA 414
E EK E+ E+ DE++KAE R +EE E+ EA
Sbjct: 1005 DEAIEKGEAEQSEEEADEEDKAEDAR-EEEYEPEKMEA 1041
Score = 30.4 bits (67), Expect = 8.2
Identities = 15/57 (26%), Positives = 31/57 (54%)
Query: 350 LRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEE 406
+R +RE + A+ +EA +K E E+ +E + +K E +E+ E ++++ E
Sbjct: 986 IREKRESVASGDDRAEEDMDEAIEKGEAEQSEEEADEEDKAEDAREEEYEPEKMEAE 1042
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 69.3 bits (168), Expect = 2e-11
Identities = 65/250 (26%), Positives = 120/250 (48%), Gaps = 33/250 (13%)
Query: 230 GILFKGKVPMVVLQDILAVRPPQIKSLPATPQGKNMTPESEVLESFPEEDSVLSHSSLSS 289
G++F + + + V+PP++ TPQ E EV++ E S +S +
Sbjct: 243 GVMFGDRPLKINHSNNAIVKPPEM-----TPQAAAKELE-EVMKRVREAQSFIS--AAIE 294
Query: 290 PSSTSSPEGPPAPPKQHS---STSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGK 346
P S S E + H+ S S + + +R K S +++ R Q+D+ R
Sbjct: 295 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSR-QKDRRRSKS 353
Query: 347 QLKLRAEREEK-----------------EKLKEEAKRAKEEAKKKKEEEKEL-KEKERRE 388
K R++ E+ EK+KE+ + +++ +K++E EKE KEKER +
Sbjct: 354 PHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGK 413
Query: 389 KREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITRF 448
+++D++ + ++++ KE K+R+ E + E+ R KE+EK +E++R K EI
Sbjct: 414 NKDRDKEREKDREKDKE---KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK 470
Query: 449 FQKPKTPQAP 458
+K K + P
Sbjct: 471 RKKDKKSRTP 480
Score = 65.5 bits (158), Expect = 2e-10
Identities = 47/186 (25%), Positives = 94/186 (50%), Gaps = 18/186 (9%)
Query: 283 SHSSLSSPSSTSSPEGPPAPPKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQE 342
S S + SP + ++ + S R+ T++ +K EK +++ ++D+E
Sbjct: 341 SRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIK---EKERVK-EKDRE 396
Query: 343 RLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQR 402
K R +E+EK KE K + +++K+ EK+ KEK+R +REK+ ++ +K++
Sbjct: 397 ------KEREREKEREKEKERGKNKDRDKEREKDREKD-KEKDREREREKEHEKDRDKEK 449
Query: 403 LKEE-RRKERQEALEAKLEEKRKKEEEKRL------REEEKRIKAEKAEITRFFQKPKTP 455
KE+ + KER++ +++EKRKK+++ R R + + R ++P
Sbjct: 450 EKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSP 509
Query: 456 QAPKTL 461
+ KT+
Sbjct: 510 RTSKTI 515
Score = 51.2 bits (121), Expect = 5e-06
Identities = 36/167 (21%), Positives = 82/167 (49%), Gaps = 3/167 (1%)
Query: 293 TSSPEGPPAPPKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRA 352
+ S E + + HS T ++ + K ++ + +R++E+ + K R
Sbjct: 359 SKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRD 418
Query: 353 EREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQ 412
+ EK++ K++ K + E +K+ E++++ KEKE+ + +EK E+EK + + E+R+K+++
Sbjct: 419 KEREKDREKDKEKDREREREKEHEKDRD-KEKEKEQDKEK-EREKDRSKEIDEKRKKDKK 476
Query: 413 EALEAK-LEEKRKKEEEKRLREEEKRIKAEKAEITRFFQKPKTPQAP 458
+ R+ R R + + ++ T K K+ ++P
Sbjct: 477 SRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSP 523
Score = 45.1 bits (105), Expect = 3e-04
Identities = 41/155 (26%), Positives = 69/155 (44%), Gaps = 8/155 (5%)
Query: 263 KNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSSTSPFPTSTPLRRIT 322
K+ TP S S S SS+ SP K+ SS SP P S
Sbjct: 476 KSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTI-KRKSSRSPSPRSR-----N 529
Query: 323 KKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELK 382
KK K E++ + +R++ER K +R+ KEKL++ + KE+ K+ + K
Sbjct: 530 KKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSK 589
Query: 383 EKERRE--KREKDEKEKAEKQRLKEERRKERQEAL 415
E + ++ + E+++ + +L EE + EA+
Sbjct: 590 EVDDKDAPRTEENKIQHNGNCQLNEENLSTKTEAV 624
Score = 42.0 bits (97), Expect = 0.003
Identities = 30/142 (21%), Positives = 58/142 (40%), Gaps = 12/142 (8%)
Query: 331 EKNKLRLQRDQERLGKQLKLR-------AEREEKEKLKEEAKRAKEEAKKKKEEEKELKE 383
E+ K R + E+ K K R A R + +E +R + + K +K
Sbjct: 458 EREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKR 517
Query: 384 KERRE-----KREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRI 438
K R + +KD+K + E+ + E R +ER ++ ++ KE+ ++ K
Sbjct: 518 KSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEK 577
Query: 439 KAEKAEITRFFQKPKTPQAPKT 460
+ K + ++ AP+T
Sbjct: 578 EHNKEPDSSVSKEVDDKDAPRT 599
Score = 41.2 bits (95), Expect = 0.005
Identities = 30/113 (26%), Positives = 53/113 (46%), Gaps = 6/113 (5%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKE-EEKELKEKERREK 389
EK+K ++D+ER ++ K + +KEK KE+ K + E + KE +EK K+K+ R
Sbjct: 426 EKDK---EKDRER--EREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTP 480
Query: 390 REKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEK 442
+ + +E RR+ + + + K K + R R K +K
Sbjct: 481 PRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDK 533
Score = 40.4 bits (93), Expect = 0.008
Identities = 38/144 (26%), Positives = 61/144 (42%), Gaps = 37/144 (25%)
Query: 332 KNKLR-LQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKR 390
KNK R +R+++R + K R EKE K+ K ++E K+KE EK+ + KE EKR
Sbjct: 413 KNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKD-RSKEIDEKR 471
Query: 391 EKDEKEKA---------EKQRLKEERRKERQEAL-------------------------- 415
+KD+K + + ERR+ R +
Sbjct: 472 KKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKK 531
Query: 416 EAKLEEKRKKEEEKRLREEEKRIK 439
+ K E++R E+R RE ++
Sbjct: 532 DKKREKERDHISERRERERSTSMR 555
Score = 37.7 bits (86), Expect = 0.052
Identities = 38/152 (25%), Positives = 65/152 (42%), Gaps = 21/152 (13%)
Query: 302 PPKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLK 361
PP+ ++++ +S+ RR + + + ++R R R +K+K
Sbjct: 480 PPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSP----RSRNKKDK-- 533
Query: 362 EEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQ--RLKE-ERRKERQEALEAK 418
KR KE + E+E R+ ++D KEK EK LKE E KE ++ +
Sbjct: 534 ---KREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKE 590
Query: 419 LEEK--RKKEEEK-------RLREEEKRIKAE 441
+++K + EE K +L EE K E
Sbjct: 591 VDDKDAPRTEENKIQHNGNCQLNEENLSTKTE 622
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 69.3 bits (168), Expect = 2e-11
Identities = 65/250 (26%), Positives = 120/250 (48%), Gaps = 33/250 (13%)
Query: 230 GILFKGKVPMVVLQDILAVRPPQIKSLPATPQGKNMTPESEVLESFPEEDSVLSHSSLSS 289
G++F + + + V+PP++ TPQ E EV++ E S +S +
Sbjct: 127 GVMFGDRPLKINHSNNAIVKPPEM-----TPQAAAKELE-EVMKRVREAQSFIS--AAIE 178
Query: 290 PSSTSSPEGPPAPPKQHS---STSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGK 346
P S S E + H+ S S + + +R K S +++ R Q+D+ R
Sbjct: 179 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSR-QKDRRRSKS 237
Query: 347 QLKLRAEREEK-----------------EKLKEEAKRAKEEAKKKKEEEKEL-KEKERRE 388
K R++ E+ EK+KE+ + +++ +K++E EKE KEKER +
Sbjct: 238 PHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGK 297
Query: 389 KREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITRF 448
+++D++ + ++++ KE K+R+ E + E+ R KE+EK +E++R K EI
Sbjct: 298 NKDRDKEREKDREKDKE---KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK 354
Query: 449 FQKPKTPQAP 458
+K K + P
Sbjct: 355 RKKDKKSRTP 364
Score = 65.5 bits (158), Expect = 2e-10
Identities = 47/186 (25%), Positives = 94/186 (50%), Gaps = 18/186 (9%)
Query: 283 SHSSLSSPSSTSSPEGPPAPPKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQE 342
S S + SP + ++ + S R+ T++ +K EK +++ ++D+E
Sbjct: 225 SRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIK---EKERVK-EKDRE 280
Query: 343 RLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQR 402
K R +E+EK KE K + +++K+ EK+ KEK+R +REK+ ++ +K++
Sbjct: 281 ------KEREREKEREKEKERGKNKDRDKEREKDREKD-KEKDREREREKEHEKDRDKEK 333
Query: 403 LKEE-RRKERQEALEAKLEEKRKKEEEKRL------REEEKRIKAEKAEITRFFQKPKTP 455
KE+ + KER++ +++EKRKK+++ R R + + R ++P
Sbjct: 334 EKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSP 393
Query: 456 QAPKTL 461
+ KT+
Sbjct: 394 RTSKTI 399
Score = 51.2 bits (121), Expect = 5e-06
Identities = 36/167 (21%), Positives = 82/167 (49%), Gaps = 3/167 (1%)
Query: 293 TSSPEGPPAPPKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRA 352
+ S E + + HS T ++ + K ++ + +R++E+ + K R
Sbjct: 243 SKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRD 302
Query: 353 EREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQ 412
+ EK++ K++ K + E +K+ E++++ KEKE+ + +EK E+EK + + E+R+K+++
Sbjct: 303 KEREKDREKDKEKDREREREKEHEKDRD-KEKEKEQDKEK-EREKDRSKEIDEKRKKDKK 360
Query: 413 EALEAK-LEEKRKKEEEKRLREEEKRIKAEKAEITRFFQKPKTPQAP 458
+ R+ R R + + ++ T K K+ ++P
Sbjct: 361 SRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSP 407
Score = 45.1 bits (105), Expect = 3e-04
Identities = 41/155 (26%), Positives = 69/155 (44%), Gaps = 8/155 (5%)
Query: 263 KNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSSTSPFPTSTPLRRIT 322
K+ TP S S S SS+ SP K+ SS SP P S
Sbjct: 360 KSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTI-KRKSSRSPSPRSR-----N 413
Query: 323 KKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELK 382
KK K E++ + +R++ER K +R+ KEKL++ + KE+ K+ + K
Sbjct: 414 KKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSK 473
Query: 383 EKERRE--KREKDEKEKAEKQRLKEERRKERQEAL 415
E + ++ + E+++ + +L EE + EA+
Sbjct: 474 EVDDKDAPRTEENKIQHNGNCQLNEENLSTKTEAV 508
Score = 42.0 bits (97), Expect = 0.003
Identities = 30/142 (21%), Positives = 58/142 (40%), Gaps = 12/142 (8%)
Query: 331 EKNKLRLQRDQERLGKQLKLR-------AEREEKEKLKEEAKRAKEEAKKKKEEEKELKE 383
E+ K R + E+ K K R A R + +E +R + + K +K
Sbjct: 342 EREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKR 401
Query: 384 KERRE-----KREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRI 438
K R + +KD+K + E+ + E R +ER ++ ++ KE+ ++ K
Sbjct: 402 KSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEK 461
Query: 439 KAEKAEITRFFQKPKTPQAPKT 460
+ K + ++ AP+T
Sbjct: 462 EHNKEPDSSVSKEVDDKDAPRT 483
Score = 41.2 bits (95), Expect = 0.005
Identities = 30/113 (26%), Positives = 53/113 (46%), Gaps = 6/113 (5%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKE-EEKELKEKERREK 389
EK+K ++D+ER ++ K + +KEK KE+ K + E + KE +EK K+K+ R
Sbjct: 310 EKDK---EKDRER--EREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTP 364
Query: 390 REKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEK 442
+ + +E RR+ + + + K K + R R K +K
Sbjct: 365 PRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDK 417
Score = 40.4 bits (93), Expect = 0.008
Identities = 38/144 (26%), Positives = 61/144 (42%), Gaps = 37/144 (25%)
Query: 332 KNKLR-LQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKR 390
KNK R +R+++R + K R EKE K+ K ++E K+KE EK+ + KE EKR
Sbjct: 297 KNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKD-RSKEIDEKR 355
Query: 391 EKDEKEKA---------EKQRLKEERRKERQEAL-------------------------- 415
+KD+K + + ERR+ R +
Sbjct: 356 KKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKK 415
Query: 416 EAKLEEKRKKEEEKRLREEEKRIK 439
+ K E++R E+R RE ++
Sbjct: 416 DKKREKERDHISERRERERSTSMR 439
Score = 37.7 bits (86), Expect = 0.052
Identities = 38/152 (25%), Positives = 65/152 (42%), Gaps = 21/152 (13%)
Query: 302 PPKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLK 361
PP+ ++++ +S+ RR + + + ++R R R +K+K
Sbjct: 364 PPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSP----RSRNKKDK-- 417
Query: 362 EEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQ--RLKE-ERRKERQEALEAK 418
KR KE + E+E R+ ++D KEK EK LKE E KE ++ +
Sbjct: 418 ---KREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKE 474
Query: 419 LEEK--RKKEEEK-------RLREEEKRIKAE 441
+++K + EE K +L EE K E
Sbjct: 475 VDDKDAPRTEENKIQHNGNCQLNEENLSTKTE 506
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 68.9 bits (167), Expect = 2e-11
Identities = 47/171 (27%), Positives = 95/171 (55%), Gaps = 16/171 (9%)
Query: 277 EEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKLR 336
E+ +V + + + + +S E P P+Q+S P V+ + +L
Sbjct: 95 EDANVFASAMMHALEVLNSQETGPTLPRQNSQ---LPAQ----------VQNGPSQEELE 141
Query: 337 LQRDQ-ERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEK 395
+QR Q + +Q +L ER E+E+++ E + +++ E E+ +E+ RE++E++ +
Sbjct: 142 IQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQERERQ 201
Query: 396 EKAEKQ-RLKEERRKERQEALEAKLEEKRKKEEEKRL-REEEKRIKAEKAE 444
E+ E+Q RL+ + R ERQE L+ + +E++++E +RL RE ++R + E+ E
Sbjct: 202 ERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLE 252
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 68.9 bits (167), Expect = 2e-11
Identities = 47/171 (27%), Positives = 95/171 (55%), Gaps = 16/171 (9%)
Query: 277 EEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKLR 336
E+ +V + + + + +S E P P+Q+S P V+ + +L
Sbjct: 95 EDANVFASAMMHALEVLNSQETGPTLPRQNSQ---LPAQ----------VQNGPSQEELE 141
Query: 337 LQRDQ-ERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEK 395
+QR Q + +Q +L ER E+E+++ E + +++ E E+ +E+ RE++E++ +
Sbjct: 142 IQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQEQLERERQERERQ 201
Query: 396 EKAEKQ-RLKEERRKERQEALEAKLEEKRKKEEEKRL-REEEKRIKAEKAE 444
E+ E+Q RL+ + R ERQE L+ + +E++++E +RL RE ++R + E+ E
Sbjct: 202 ERLERQERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLE 252
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 68.9 bits (167), Expect = 2e-11
Identities = 37/127 (29%), Positives = 86/127 (67%), Gaps = 11/127 (8%)
Query: 336 RLQRDQERLGKQLKLRAE---REEKEKLKEEAKRAKEEAKKKKEEEK----ELKEKERRE 388
+++ +E++ +Q K+R + R+E+EK++E+ KR ++EAK ++EEK E K +E+ E
Sbjct: 439 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEE 498
Query: 389 KREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEE----EKRLREEEKRIKAEKAE 444
K + E++ E+++++EE +++ QE + + E+ R++EE ++++ E+E++I+ ++ +
Sbjct: 499 KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEK 558
Query: 445 ITRFFQK 451
+ R +K
Sbjct: 559 MWRQEEK 565
Score = 66.6 bits (161), Expect = 1e-10
Identities = 36/118 (30%), Positives = 79/118 (66%), Gaps = 8/118 (6%)
Query: 336 RLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEE---EKELKEKERREKREK 392
+++ +E++ +Q ++ E+EEK + +EE KEE +++EE EKE K +E EK +
Sbjct: 390 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHE 449
Query: 393 DEKEKAEKQRLKEE---RRKERQEALEAKL--EEKRKKEEEKRLREEEKRIKAEKAEI 445
EK + ++++ +EE R +E+++ EAK+ +E++ +E+E+++RE+E+++ ++ +I
Sbjct: 450 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKI 507
Score = 65.9 bits (159), Expect = 2e-10
Identities = 48/158 (30%), Positives = 92/158 (58%), Gaps = 20/158 (12%)
Query: 303 PKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKL--RL-QRDQERLGKQLKLRAEREEK-- 357
P+Q L+ ++ K ++ E+N+L RL Q+ +E++ +Q + E EEK
Sbjct: 320 PQQQLQAEADHLGKELQSVSAK-LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQ 378
Query: 358 ---EKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEK-EKAEKQRLKEERRKERQE 413
EK++E+ ++ +E+ +K + +E+ + EKE + +R+++ EK EK R +EE E++E
Sbjct: 379 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 438
Query: 414 ---ALEAKL-------EEKRKKEEEKRLREEEKRIKAE 441
LE K+ E++ K++EE+++RE+EKR + E
Sbjct: 439 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 476
Score = 65.5 bits (158), Expect = 2e-10
Identities = 44/142 (30%), Positives = 83/142 (58%), Gaps = 19/142 (13%)
Query: 320 RITKKFVKGSTEKNKLRLQRD-----QERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKK 374
+I ++ K ++ K+R Q + +E++ +Q ++ E+EEK + +EE KEE ++
Sbjct: 383 KIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRE 442
Query: 375 KEEEKELKEK--ERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEK--- 429
EE+ +EK E+ EKR+++EK + +++R ++E + RQE + EEK +++EEK
Sbjct: 443 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWR 502
Query: 430 ---------RLREEEKRIKAEK 442
++REEEKR + E+
Sbjct: 503 QEEKIHEQEKIREEEKRQEQEE 524
Score = 63.9 bits (154), Expect = 7e-10
Identities = 38/112 (33%), Positives = 73/112 (65%), Gaps = 7/112 (6%)
Query: 336 RLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEK 395
+++ +E++ +Q ++ E+EEK +EE K ++E K +++EEK +++E+ ++EK +
Sbjct: 593 KIREQEEKIREQEEMTQEQEEKMGEQEE-KMCEQEEKMQEQEEKMRRQEEKIREQEKKIR 651
Query: 396 EKAEKQRLKEERRKERQEAL---EAKL---EEKRKKEEEKRLREEEKRIKAE 441
E+ EK R +EE +E++E + E K+ EEK +++EEK R+EEK + E
Sbjct: 652 EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 703
Score = 63.2 bits (152), Expect = 1e-09
Identities = 33/114 (28%), Positives = 72/114 (63%), Gaps = 8/114 (7%)
Query: 338 QRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEK 397
Q +E++G+Q + E+EEK + +EE R +EE K +E+EK+++E+E + + +++ ++
Sbjct: 609 QEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEE--KIREQEKKIREQEEKIREQEEMMQE 666
Query: 398 AEKQRLKEERRKERQEALEAKLEEKRKKEEEK------RLREEEKRIKAEKAEI 445
E++ ++E + QE + EEK +++EEK RLR++E++++ + +
Sbjct: 667 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 720
Score = 62.4 bits (150), Expect = 2e-09
Identities = 41/131 (31%), Positives = 80/131 (61%), Gaps = 15/131 (11%)
Query: 336 RLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEK-ELKEKERREKR---E 391
++Q +E++ +Q + E+EEK + +EE KEE +++EE E +EK RR++ E
Sbjct: 376 KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 435
Query: 392 KDEK-----EKAEKQRLKEERRKERQEALEAKLEEKRKKEE------EKRLREEEKRIKA 440
K+EK EK +Q E+ ++RQE + + +EKR+++E E+++RE+E++I+
Sbjct: 436 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 495
Query: 441 EKAEITRFFQK 451
++ ++ R +K
Sbjct: 496 QEEKMWRQEEK 506
Score = 61.6 bits (148), Expect = 3e-09
Identities = 39/129 (30%), Positives = 81/129 (62%), Gaps = 13/129 (10%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAERE--EKEKLKEEAKRAKEEAKKKKEEE-KELKEKERR 387
++ K+R Q ++ R ++ R E + E+EK++EE KR ++E ++EE+ +E +E R+
Sbjct: 482 QEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQ 541
Query: 388 EKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKK---------EEEKRLREEEKRI 438
+++ +++EK KQ K R++E+ E K+ E+ +K E+E+++RE+E++I
Sbjct: 542 KEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKI 601
Query: 439 KAEKAEITR 447
+ E+ E+T+
Sbjct: 602 R-EQEEMTQ 609
Score = 61.2 bits (147), Expect = 4e-09
Identities = 27/121 (22%), Positives = 81/121 (66%), Gaps = 6/121 (4%)
Query: 327 KGSTEKNKLRLQRDQERLGKQLKLRAEREEK-----EKLKEEAKRAKEEAKKKKEEEKEL 381
K + + ++++ +E++ +Q + ++EEK EK+ + ++ +E+ +K +E+E+++
Sbjct: 542 KEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKI 601
Query: 382 KEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAE 441
+E+E +E++EK +++++ E+ K +++ + + +E++ +E+EK++RE+E++I+ +
Sbjct: 602 REQEEM-TQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 660
Query: 442 K 442
+
Sbjct: 661 E 661
Score = 60.5 bits (145), Expect = 7e-09
Identities = 32/117 (27%), Positives = 74/117 (63%), Gaps = 11/117 (9%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKE--------KLKEEAKRAKEEAKKKKEEEKELK 382
E+ K+R Q ++ + ++++ + +R+E+E K++E+ ++ +E+ +K +E+++
Sbjct: 449 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIH 508
Query: 383 EKER---REKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEK 436
E+E+ EKR++ E+ ++++++E+ RQ+ + EEK +K+EEK R+EEK
Sbjct: 509 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEK 565
Score = 60.1 bits (144), Expect = 1e-08
Identities = 42/139 (30%), Positives = 85/139 (61%), Gaps = 20/139 (14%)
Query: 331 EKNKLRLQRD-----QERLGKQLKLRAEREEKEKLKEEAKRAKE---EAKKKKEEEKELK 382
++ K+R Q + +E++ +Q ++ E+EEK + EE +E E ++K++EE++++
Sbjct: 408 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR 467
Query: 383 EKERREKREKDEKEKAEKQRLKEERRKERQEAL---EAKL-------EEKRKKEEEKRLR 432
E+E+R+++E + EK R +EE+ +E++E + E K+ EE++++E+E+ R
Sbjct: 468 EQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWR 527
Query: 433 EEEKRIKAEKAEITRFFQK 451
+EEK E+ EI R +K
Sbjct: 528 QEEK--IREQEEIWRQKEK 544
Score = 59.7 bits (143), Expect = 1e-08
Identities = 38/120 (31%), Positives = 74/120 (61%), Gaps = 8/120 (6%)
Query: 332 KNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKRE 391
+ K ++ +E++ KQ + +EEK +EE R +EE ++EE+ +E++ RE+ E
Sbjct: 540 RQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEE 599
Query: 392 KDE------KEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEI 445
K +E+ EK +EE+ E++E ++ + EEK +++EEK +RE+EK+I+ ++ +I
Sbjct: 600 KIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ-EEKMRRQEEK-IREQEKKIREQEEKI 657
Score = 58.9 bits (141), Expect = 2e-08
Identities = 37/112 (33%), Positives = 71/112 (63%), Gaps = 5/112 (4%)
Query: 336 RLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEE---EKELKEKERREK-RE 391
++ R +E++ +Q + E+EEK + +EE + +EE ++EE E+E K +E+ EK R
Sbjct: 579 KVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRR 638
Query: 392 KDEKEKAEKQRLKEERRKER-QEALEAKLEEKRKKEEEKRLREEEKRIKAEK 442
++EK + ++++++E+ K R QE + + EEK ++EEK +EEK + E+
Sbjct: 639 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 690
Score = 58.5 bits (140), Expect = 3e-08
Identities = 34/118 (28%), Positives = 76/118 (64%), Gaps = 11/118 (9%)
Query: 332 KNKLRLQRDQERLGKQLKLRAEREEK-----EKLKEEAKRAKEEAKKKKEEEKELKEKER 386
K + ++ R +E++ Q + E+EEK EK++E+ ++ +E+ +K +E+E+ +E+E
Sbjct: 554 KQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEE 613
Query: 387 R--EKREK--DEKEKAEKQRLKEERRKERQEALEAKLEEKRKK--EEEKRLREEEKRI 438
+ E+ EK +++EK ++Q K R++E+ E K+ E+ +K E+E+ ++E+E+++
Sbjct: 614 KMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 671
Score = 56.2 bits (134), Expect = 1e-07
Identities = 35/132 (26%), Positives = 79/132 (59%), Gaps = 20/132 (15%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEK-----EKLKEEAKRAKEEAKKKKEEEKELKEKE 385
++ + ++ R +E++ +Q + E+EEK EK+ E+ K +EE K++E++E+ +E
Sbjct: 473 QEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEE---KRQEQEEMWRQE 529
Query: 386 ----------RREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKK--EEEKRLRE 433
R++++ +++EK KQ K R++E+ E K+ E+ +K +E+++RE
Sbjct: 530 EKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIRE 589
Query: 434 EEKRIKAEKAEI 445
+E++I+ ++ +I
Sbjct: 590 QEEKIREQEEKI 601
Score = 51.2 bits (121), Expect = 5e-06
Identities = 31/95 (32%), Positives = 60/95 (63%), Gaps = 6/95 (6%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEE---EKELKEKERR 387
++ + +++R +E++ +Q K E+EEK + +EE + +EE ++EE E+E K +E+
Sbjct: 630 QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 689
Query: 388 EKREKDEKEKAEKQ---RLKEERRKERQEALEAKL 419
EK + E++ E++ R +EE+ +E QE LEA +
Sbjct: 690 EKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 724
Score = 47.8 bits (112), Expect = 5e-05
Identities = 86/447 (19%), Positives = 182/447 (40%), Gaps = 53/447 (11%)
Query: 320 RITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREE----KEKLKEEAKRAKEEAKK-- 373
++ +K +EK++++L K+LK + ER + +++L+ EA +E +
Sbjct: 286 KLQEKLQLVESEKSEIQLNV------KELKRKLERAKLLLPQQQLQAEADHLGKELQSVS 339
Query: 374 -KKEEEKELKEKERREKREKDEKEKAEKQRLKE-ERRKERQEALEAKLEEKRKKEEEKRL 431
K + + E E R ++++EK ++++++E E + + QE + EEK +++EEK
Sbjct: 340 AKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMR 399
Query: 432 REE----EKRIKAEKAEITRFFQKPKTPQAPKTLAGSCGKFAPFEIKEHMVLAPRRRTAF 487
R+E EK K + E + ++ K + + + K E K H + +
Sbjct: 400 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH----EQEKIRE 455
Query: 488 HPDLCSQLDQLLQQQSGEFSFLKDLKGRQPLRSGPTHVSTRNADIFNSDVVIVERGKGDG 547
+ + +++ +Q+ + K + + +R + + ++ + I E+ K
Sbjct: 456 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEK--- 512
Query: 548 VPERRKFGRMKLLQFCENHRPAYWGTWNKKTAL------IRARDP--WAQDTKLLDYEVD 599
+ E K + + E W +K + IR ++ W Q+ K+ D E
Sbjct: 513 IREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEK 572
Query: 600 SDEE----WEEEEPGESLSHSEGDDDDDMGEDEDEDDGFFVPHGYLSEDEGVTEECADPE 655
E+ W +EE + ++ + E E+ G E EE +
Sbjct: 573 IREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ 632
Query: 656 NHKVR--------QKLKAKEWDEFLAKGKRFRVLQPVKIGCVWAADRDCAGDDLKVLQQF 707
K+R Q+ K +E +E + + + Q K +W + + K+ +Q
Sbjct: 633 EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK---MWEQEEKMCEQEEKMQEQ- 688
Query: 708 AACFLETLPAQEEQTPKASKRERRDEQ 734
E + QEE+ + R R+ E+
Sbjct: 689 ----EEKMRRQEEKMWEQEVRLRQQEE 711
Score = 31.6 bits (70), Expect = 3.7
Identities = 41/206 (19%), Positives = 91/206 (44%), Gaps = 16/206 (7%)
Query: 251 PQIKSLPATPQGKNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSSTS 310
P LP P T +S++ E+ ++ + H ++PS + K ++ T+
Sbjct: 101 PTHPHLPTHPMMSKETRQSKLAEA---KEQLTDHHPQTNPS-VGTAASDTKKKKINNGTN 156
Query: 311 PFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLK-LRAEREE--------KEKLK 361
P T++ + K S + + L+R+ E ++ L ++ E + +K
Sbjct: 157 PETTTSGGCHSPEDEQKASHQHQEA-LRRELEAQVHTIRILTCQKTELQMALYYSQHAVK 215
Query: 362 EEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEK--QRLKEERRKERQEALEAKL 419
+ A++ + + K E E+ +K+KA++ + L +ER E +
Sbjct: 216 QLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTI 275
Query: 420 EEKRKKEEEKRLREEEKRIKAEKAEI 445
++ KE+ +L+E+ + +++EK+EI
Sbjct: 276 TDEELKEKNAKLQEKLQLVESEKSEI 301
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 68.2 bits (165), Expect = 4e-11
Identities = 42/139 (30%), Positives = 88/139 (63%), Gaps = 13/139 (9%)
Query: 320 RITKKFVKGSTEKNKLRLQRD-----QERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKK 374
+I ++ K ++ K+R Q + +E++ +Q ++ E+EEK + +EE KEE ++
Sbjct: 322 KIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR 381
Query: 375 KEE---EKELKEKERREKREKDEKEKAEKQRLKEE---RRKERQEALEAKL--EEKRKKE 426
+EE EKE K +E EK + EK + ++++ +EE R +E+++ EAK+ +E++ +E
Sbjct: 382 QEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 441
Query: 427 EEKRLREEEKRIKAEKAEI 445
+E+++RE+EK++ ++ +I
Sbjct: 442 QEEKIREQEKKMWRQEEKI 460
Score = 66.6 bits (161), Expect = 1e-10
Identities = 31/112 (27%), Positives = 77/112 (68%), Gaps = 6/112 (5%)
Query: 336 RLQRDQERLGKQLKLRAEREEK-----EKLKEEAKRAKEEAKKKKEEEKELKEKERREKR 390
++ R +E++ +Q + R E+EEK EK++E+ ++ +E+ +K +E+E++++E+E +
Sbjct: 585 KVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQE 644
Query: 391 EKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEK 442
++++ + E++ ++E + + QE + EEK + E+EK++RE+E++I+ ++
Sbjct: 645 QEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR-EQEKKIREQEEKIREQE 695
Score = 64.7 bits (156), Expect = 4e-10
Identities = 42/148 (28%), Positives = 89/148 (60%), Gaps = 32/148 (21%)
Query: 336 RLQRDQERLGKQLKLRAE---REEKEKLKEEAKRAKEEAKKKKEEEK----ELKEKERRE 388
+++ +E++ +Q K+R + R+E+EK++E+ KR ++EAK ++EEK E K +E+ +
Sbjct: 392 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK 451
Query: 389 KREKDEKEKAEKQRLKEERRKERQEAL---EAKL----------------EEKRKKEEEK 429
K + E++ E+++++EE +++ QE + E K+ EEK +K+EEK
Sbjct: 452 KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEK 511
Query: 430 ------RLREEEKRIKAEKAEITRFFQK 451
++RE+E++I+ ++ ++ R +K
Sbjct: 512 VWRQEEKIREQEEKIREQEEKMWRQEEK 539
Score = 64.3 bits (155), Expect = 5e-10
Identities = 43/131 (32%), Positives = 77/131 (58%), Gaps = 19/131 (14%)
Query: 331 EKNKLRLQRD-----QERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEK- 384
++ K+R Q + +E++ +Q ++ E+EEK + +EE KEE ++ EE+ +EK
Sbjct: 347 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKI 406
Query: 385 -ERREKREKDEK----EKAEKQRLKEERRKERQEALEAKLEEKRKK--------EEEKRL 431
E+ EKR+++EK EK ++Q K R++E+ E K+ E+ KK E++++
Sbjct: 407 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKI 466
Query: 432 REEEKRIKAEK 442
REEEKR + E+
Sbjct: 467 REEEKRQEQEE 477
Score = 64.3 bits (155), Expect = 5e-10
Identities = 35/115 (30%), Positives = 82/115 (71%), Gaps = 6/115 (5%)
Query: 336 RLQRDQERLGKQLKLRAERE---EKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREK 392
++ R +E++ +Q ++ E E E+EK+ EE KR ++E K ++EEK +++E+ ++E+
Sbjct: 532 KMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEE 591
Query: 393 DEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITR 447
+E+ EK++ +EE+ +++E + + +E++ +E+E+++RE+E++I+ E+ E+T+
Sbjct: 592 KIREQEEKRQEQEEKMWKQEEKI--REQEEKIQEQEEKIREQEEKIR-EQEEMTQ 643
Score = 63.9 bits (154), Expect = 7e-10
Identities = 52/172 (30%), Positives = 94/172 (54%), Gaps = 34/172 (19%)
Query: 303 PKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKL--RL-QRDQERLGKQLKLRAEREEK-- 357
P+Q L+ ++ K ++ E+N+L RL Q+ +E++ +Q + E EEK
Sbjct: 259 PQQQLQAEADHLGKELQSVSAK-LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQ 317
Query: 358 ---EKLKEEAKRAKEEAKKKKEEEKELKEKERREKR------EKDEK---------EKAE 399
EK++E+ ++ +E+ +K + +E+ + EKE + +R EK+EK EK E
Sbjct: 318 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 377
Query: 400 KQRLKEERRKERQE---ALEAKL-------EEKRKKEEEKRLREEEKRIKAE 441
K R +EE E++E LE K+ E++ K++EE+++RE+EKR + E
Sbjct: 378 KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 429
Score = 63.5 bits (153), Expect = 9e-10
Identities = 47/165 (28%), Positives = 92/165 (55%), Gaps = 7/165 (4%)
Query: 338 QRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEK 397
Q ++++ +Q + E+EEK +EE R +EE K++++EEK K++E+ ++E+ +E+
Sbjct: 566 QEQEDKMWRQEEKIREQEEKVWRQEEKIREQEE-KRQEQEEKMWKQEEKIREQEEKIQEQ 624
Query: 398 AEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITRFFQKPKTPQA 457
EK R +EE+ +E++E + + EEK ++EEK +EE K ++ E T + Q+ K +
Sbjct: 625 EEKIREQEEKIREQEEMTQEQ-EEKMGEQEEKMCEQEE---KMQEQEETMWRQEEKIREQ 680
Query: 458 PKTLAGSCGKFAPFEIKEHMVLAPRRRTAFHPDLCSQLDQLLQQQ 502
K + K E +E M + +C Q +++ +Q+
Sbjct: 681 EKKIREQEEKIR--EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 723
Score = 63.2 bits (152), Expect = 1e-09
Identities = 40/131 (30%), Positives = 81/131 (61%), Gaps = 15/131 (11%)
Query: 336 RLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEK-ELKEKERREKR---E 391
+++ +E++ +Q ++ E+EEK + +EE KEE +++EE E +EK RR++ E
Sbjct: 329 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 388
Query: 392 KDEK-----EKAEKQRLKEERRKERQEALEAKLEEKRKKEE------EKRLREEEKRIKA 440
K+EK EK +Q E+ ++RQE + + +EKR+++E E+++RE+E++I+
Sbjct: 389 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 448
Query: 441 EKAEITRFFQK 451
++ ++ R +K
Sbjct: 449 QEKKMWRQEEK 459
Score = 62.0 bits (149), Expect = 3e-09
Identities = 37/117 (31%), Positives = 75/117 (64%), Gaps = 7/117 (5%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKR 390
++ + +++ +E++ +Q ++ E+EEK +EE K ++E K +++EE +++E+ ++
Sbjct: 622 QEQEEKIREQEEKIREQEEMTQEQEEKMGEQEE-KMCEQEEKMQEQEETMWRQEEKIREQ 680
Query: 391 EKDEKEKAEKQRLKEERRKERQEAL---EAKL---EEKRKKEEEKRLREEEKRIKAE 441
EK +E+ EK R +EE +E++E + E K+ EEK +++EEK R+EEK + E
Sbjct: 681 EKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 737
Score = 61.6 bits (148), Expect = 3e-09
Identities = 39/124 (31%), Positives = 78/124 (62%), Gaps = 12/124 (9%)
Query: 331 EKNKLRLQRD-----QERLGKQLKLRAEREEKEKLKEEAKRAKE---EAKKKKEEEKELK 382
++ K+R Q + +E++ +Q ++ E+EEK + EE +E E ++K++EE++++
Sbjct: 361 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR 420
Query: 383 EKERREKREKDEKEKAEKQRLKEERRKERQEAL---EAKLEEKRK-KEEEKRLREEEKRI 438
E+E+R+++E + EK R +EE+ +E+++ + E K+ E+ K +EEEKR +EE
Sbjct: 421 EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR 480
Query: 439 KAEK 442
+ EK
Sbjct: 481 QEEK 484
Score = 61.6 bits (148), Expect = 3e-09
Identities = 39/119 (32%), Positives = 74/119 (62%), Gaps = 7/119 (5%)
Query: 331 EKNKLRLQRDQERLGKQLKLRAE---REEKEKLKEEAKRAKEEAKKKKEEEKELKEKERR 387
+K K+ Q ++ R ++ R E RE++EK++E+ ++ + +K +E+E+ +E+E+
Sbjct: 494 QKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKM 553
Query: 388 EKREKD-EKEKAEKQRLKEERRKERQEALEAKL---EEKRKKEEEKRLREEEKRIKAEK 442
++EK E+EK ++Q K R++E+ E K+ EEK +++EEKR +EEK K E+
Sbjct: 554 HEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEE 612
Score = 60.8 bits (146), Expect = 6e-09
Identities = 41/134 (30%), Positives = 85/134 (63%), Gaps = 10/134 (7%)
Query: 320 RITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAE---REEKEKLKEEAKRAK-----EEA 371
+I K+ K ++ K+R Q ++ R ++ R E RE++E +EE K + EE
Sbjct: 504 KIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEE 563
Query: 372 KKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRL 431
K++++E+K +++E+ ++E+ + EK R +EE+R+E++E + K EEK +++EEK +
Sbjct: 564 KRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMW-KQEEKIREQEEK-I 621
Query: 432 REEEKRIKAEKAEI 445
+E+E++I+ ++ +I
Sbjct: 622 QEQEEKIREQEEKI 635
Score = 60.1 bits (144), Expect = 1e-08
Identities = 45/152 (29%), Positives = 83/152 (54%), Gaps = 29/152 (19%)
Query: 320 RITKKFVKGSTEKNKL-----RLQRDQERLGKQL-----KLRAEREE------------- 356
++ K +K E+ KL +LQ + + LGK+L KL+A+ EE
Sbjct: 241 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 300
Query: 357 -----KEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEK-EKAEKQRLKEERRKE 410
+EK++E ++ +E+ +K +E+E++++E+E + +R+++ EK EK R +EE E
Sbjct: 301 KMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 360
Query: 411 RQEALEAKLEEKRKKEEEKRLREEEKRIKAEK 442
++E + + E +KEE+ R +EE K EK
Sbjct: 361 KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 392
Score = 60.1 bits (144), Expect = 1e-08
Identities = 34/116 (29%), Positives = 77/116 (66%), Gaps = 7/116 (6%)
Query: 331 EKNKLRLQ----RDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKER 386
++ K+R Q R++E++ +Q K+ EE+++ ++E K ++E K +++EEK +++E+
Sbjct: 536 QEEKIREQEEMWREEEKMHEQEKIW---EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEK 592
Query: 387 REKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEK 442
++E+ +E+ EK +EE+ +E++E ++ + E+ R++EE+ R +EE + + EK
Sbjct: 593 IREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEK 648
Score = 60.1 bits (144), Expect = 1e-08
Identities = 35/108 (32%), Positives = 72/108 (66%), Gaps = 8/108 (7%)
Query: 338 QRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERR-EKREKDEKE 396
Q +E++G+Q + E+EEK + +EE +EE K +E+EK+++E+E + ++E+ +E
Sbjct: 643 QEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEE--KIREQEKKIREQEEKIREQEEMMQE 700
Query: 397 KAEKQRLKEERRKERQEALEAKLEEKRKKEE-----EKRLREEEKRIK 439
+ EK +EE+ E++E ++ + E+ R++EE E RLR++E++++
Sbjct: 701 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748
Score = 57.8 bits (138), Expect = 5e-08
Identities = 35/112 (31%), Positives = 73/112 (65%), Gaps = 6/112 (5%)
Query: 340 DQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAE 399
+QE + +Q + E+EEK + +EE +EE K +E+E++++E+E + R++++ + E
Sbjct: 487 EQEEIWRQKEKMHEQEEKIRKQEEKVWRQEE--KIREQEEKIREQEEKMWRQEEKIREQE 544
Query: 400 KQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITRFFQK 451
+ +EE+ E+++ E EEKR+++E+K R+EEK I+ ++ ++ R +K
Sbjct: 545 EMWREEEKMHEQEKIWE---EEKRQEQEDKMWRQEEK-IREQEEKVWRQEEK 592
Score = 57.4 bits (137), Expect = 6e-08
Identities = 37/113 (32%), Positives = 67/113 (59%), Gaps = 2/113 (1%)
Query: 332 KNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKRE 391
+ K ++ +E++ KQ + +EEK + +EE R +EE ++EE+ +E+ RE+ +
Sbjct: 493 RQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEK 552
Query: 392 KDEKEKA--EKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEK 442
E+EK E++R ++E + RQE + EEK ++EEK +EEKR + E+
Sbjct: 553 MHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEE 605
Score = 57.0 bits (136), Expect = 8e-08
Identities = 33/107 (30%), Positives = 69/107 (64%), Gaps = 2/107 (1%)
Query: 336 RLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEK 395
++Q +E++ +Q + E+EE + +EE K ++E K ++EEK +++E ++E+ +
Sbjct: 620 KIQEQEEKIREQEEKIREQEEMTQEQEE-KMGEQEEKMCEQEEKMQEQEETMWRQEEKIR 678
Query: 396 EKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEK 442
E+ +K R +EE+ +E++E ++ + EEK ++EEK +EEK + E+
Sbjct: 679 EQEKKIREQEEKIREQEEMMQEQ-EEKMWEQEEKMCEQEEKMQEQEE 724
Score = 56.6 bits (135), Expect = 1e-07
Identities = 33/118 (27%), Positives = 70/118 (59%), Gaps = 12/118 (10%)
Query: 336 RLQRDQERLGKQLKLRAERE---------EKEKLKEEAKRAKEEAKKKKEEEKELKEKE- 385
++ R +E++ +Q K+R E + ++EK+ E+ + +++ K ++EEK K++E
Sbjct: 452 KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEK 511
Query: 386 --RREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAE 441
R+E++ ++++EK +Q K R++E+ E E+ K E++++ EEEKR + E
Sbjct: 512 VWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQE 569
Score = 54.3 bits (129), Expect = 5e-07
Identities = 36/110 (32%), Positives = 75/110 (68%), Gaps = 5/110 (4%)
Query: 339 RDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKRE--KDEKE 396
R +E++ +Q + ++EEK +EE R +EE +++EE+ +E++ RE+ E ++E++
Sbjct: 493 RQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEK 552
Query: 397 KAEKQRL-KEERRKERQEALEAKLEEKRKKEEEKRLREEEK-RIKAEKAE 444
E++++ +EE+R+E+++ + + EEK +++EEK R+EEK R + EK +
Sbjct: 553 MHEQEKIWEEEKRQEQEDKM-WRQEEKIREQEEKVWRQEEKIREQEEKRQ 601
Score = 45.1 bits (105), Expect = 3e-04
Identities = 22/93 (23%), Positives = 60/93 (64%), Gaps = 5/93 (5%)
Query: 336 RLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEK 395
++Q +E + +Q + RE+++K++E+ ++ +E+ + +E+E+++ E +E++ +++
Sbjct: 662 KMQEQEETMWRQEE--KIREQEKKIREQEEKIREQEEMMQEQEEKMWE---QEEKMCEQE 716
Query: 396 EKAEKQRLKEERRKERQEALEAKLEEKRKKEEE 428
EK ++Q K R++E+ E +L ++ +K +E
Sbjct: 717 EKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
Score = 43.1 bits (100), Expect = 0.001
Identities = 72/372 (19%), Positives = 159/372 (42%), Gaps = 33/372 (8%)
Query: 320 RITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREE----KEKLKEEAKRAKEEAKK-- 373
++ +K +EK++++L K+LK + ER + +++L+ EA +E +
Sbjct: 225 KLQEKLQLVESEKSEIQLNV------KELKRKLERAKLLLPQQQLQAEADHLGKELQSVS 278
Query: 374 -KKEEEKELKEKERREKREKDEKEKAEKQRLKE-ERRKERQEALEAKLEEKRKKEEEKRL 431
K + + E E R ++++EK ++++++E E + + QE + EEK +++EEK
Sbjct: 279 AKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMR 338
Query: 432 REE----EKRIKAEKAEITRFFQKPKTPQAPKTLAGSCGKFAPFEIKEHMVLAPRRRTAF 487
R+E EK K + E + ++ K + + + K +E M+ +
Sbjct: 339 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM---WEKEEKMRRQEEMMWEKEEKIRE 395
Query: 488 HPDLCSQLDQLLQQQSGEFSFLKDLKGRQPLRSGPTHVSTRNADIFNSDVVIVERGKGDG 547
+ + +++ +Q+ K ++ ++ + + + I + I E+ K
Sbjct: 396 LEEKMHEQEKIREQEEKRQEEEK-IREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW 454
Query: 548 VPERRKFGRMKLLQFCENHRPAYWGTWNKKTALIRARDPWAQDTKLLDYE--VDSDEE-- 603
E + + K+ + E R W ++ + + W Q K+ + E + EE
Sbjct: 455 RQEEKIHEQEKIRE--EEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKV 512
Query: 604 WEEEEPGESLSHSEGDDDDDMGEDED---EDDGFFVPHGYLSEDEGVTEE--CADPENHK 658
W +EE + ++ M E+ E + + + E E + EE + E+
Sbjct: 513 WRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKM 572
Query: 659 VRQKLKAKEWDE 670
RQ+ K +E +E
Sbjct: 573 WRQEEKIREQEE 584
Score = 31.6 bits (70), Expect = 3.7
Identities = 41/206 (19%), Positives = 91/206 (44%), Gaps = 16/206 (7%)
Query: 251 PQIKSLPATPQGKNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSSTS 310
P LP P T +S++ E+ ++ + H ++PS + K ++ T+
Sbjct: 40 PTHPHLPTHPMMSKETRQSKLAEA---KEQLTDHHPQTNPS-VGTAASDTKKKKINNGTN 95
Query: 311 PFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLK-LRAEREE--------KEKLK 361
P T++ + K S + + L+R+ E ++ L ++ E + +K
Sbjct: 96 PETTTSGGCHSPEDEQKASHQHQEA-LRRELEAQVHTIRILTCQKTELQMALYYSQHAVK 154
Query: 362 EEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEK--QRLKEERRKERQEALEAKL 419
+ A++ + + K E E+ +K+KA++ + L +ER E +
Sbjct: 155 QLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTI 214
Query: 420 EEKRKKEEEKRLREEEKRIKAEKAEI 445
++ KE+ +L+E+ + +++EK+EI
Sbjct: 215 TDEELKEKNAKLQEKLQLVESEKSEI 240
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 67.8 bits (164), Expect = 5e-11
Identities = 48/156 (30%), Positives = 87/156 (55%), Gaps = 12/156 (7%)
Query: 292 STSSPEGPPAPPKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLR 351
S E P + SS P + LRR + + + E+++ L+R Q L ++ +LR
Sbjct: 326 SEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEA-LRRQQ--LLQEQQLR 382
Query: 352 AEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKER 411
+ E K +L E ++ E+ +KE+ + L+E++RRE+ + ++E+ +++R +EE+R+
Sbjct: 383 EQEEYKRQLLAERQKRIEQ---QKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLE 439
Query: 412 QEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITR 447
+ LE +RK+EEE+R EEEKR + E R
Sbjct: 440 E------LERRRKEEEERRRAEEEKRRVEREQEYIR 469
Score = 44.7 bits (104), Expect = 4e-04
Identities = 51/227 (22%), Positives = 98/227 (43%), Gaps = 77/227 (33%)
Query: 297 EGPPAPPKQHSSTSPF--PTSTPLRRITKK-------FVKGSTEKNKLRLQRDQERLGKQ 347
EG P H + F P + P R +KK F++G KN ++ + E+L K
Sbjct: 228 EGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQ-RPSTEQLLKH 286
Query: 348 LKLRAEREEKE---KLKEEAKRAKEEAKKK----------KEEEKELKEKE--------- 385
+R + E++ +LK+ R +++ +K +EEE+E+ E+E
Sbjct: 287 PFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNV 346
Query: 386 -------------RREKREKDE--------------------------------KEKAEK 400
++E +E+ E ++K ++
Sbjct: 347 PGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQR 406
Query: 401 QRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITR 447
+RL+E++R+ER+ + + E++R+++EEKR EE +R + E+ E R
Sbjct: 407 RRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRR 453
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 67.8 bits (164), Expect = 5e-11
Identities = 48/156 (30%), Positives = 87/156 (55%), Gaps = 12/156 (7%)
Query: 292 STSSPEGPPAPPKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLR 351
S E P + SS P + LRR + + + E+++ L+R Q L ++ +LR
Sbjct: 326 SEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEA-LRRQQ--LLQEQQLR 382
Query: 352 AEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKER 411
+ E K +L E ++ E+ +KE+ + L+E++RRE+ + ++E+ +++R +EE+R+
Sbjct: 383 EQEEYKRQLLAERQKRIEQ---QKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLE 439
Query: 412 QEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITR 447
+ LE +RK+EEE+R EEEKR + E R
Sbjct: 440 E------LERRRKEEEERRRAEEEKRRVEREQEYIR 469
Score = 44.7 bits (104), Expect = 4e-04
Identities = 51/227 (22%), Positives = 98/227 (43%), Gaps = 77/227 (33%)
Query: 297 EGPPAPPKQHSSTSPF--PTSTPLRRITKK-------FVKGSTEKNKLRLQRDQERLGKQ 347
EG P H + F P + P R +KK F++G KN ++ + E+L K
Sbjct: 228 EGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQ-RPSTEQLLKH 286
Query: 348 LKLRAEREEKE---KLKEEAKRAKEEAKKK----------KEEEKELKEKE--------- 385
+R + E++ +LK+ R +++ +K +EEE+E+ E+E
Sbjct: 287 PFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNV 346
Query: 386 -------------RREKREKDE--------------------------------KEKAEK 400
++E +E+ E ++K ++
Sbjct: 347 PGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQR 406
Query: 401 QRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITR 447
+RL+E++R+ER+ + + E++R+++EEKR EE +R + E+ E R
Sbjct: 407 RRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRR 453
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 67.8 bits (164), Expect = 5e-11
Identities = 48/156 (30%), Positives = 87/156 (55%), Gaps = 12/156 (7%)
Query: 292 STSSPEGPPAPPKQHSSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLR 351
S E P + SS P + LRR + + + E+++ L+R Q L ++ +LR
Sbjct: 326 SEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEA-LRRQQ--LLQEQQLR 382
Query: 352 AEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKER 411
+ E K +L E ++ E+ +KE+ + L+E++RRE+ + ++E+ +++R +EE+R+
Sbjct: 383 EQEEYKRQLLAERQKRIEQ---QKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLE 439
Query: 412 QEALEAKLEEKRKKEEEKRLREEEKRIKAEKAEITR 447
+ LE +RK+EEE+R EEEKR + E R
Sbjct: 440 E------LERRRKEEEERRRAEEEKRRVEREQEYIR 469
Score = 57.4 bits (137), Expect = 6e-08
Identities = 44/172 (25%), Positives = 88/172 (51%), Gaps = 7/172 (4%)
Query: 319 RRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKE-EAKRAKEEAKKKKEE 377
+RI ++ + + + R +R+ R ++ + R E+EEK +L+E E +R +EE +++ EE
Sbjct: 397 KRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEE 456
Query: 378 EKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKR 437
EK E+E+ R + E+E+ + L+++ +E+ LE + E + + +RL+ + ++
Sbjct: 457 EKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQ 516
Query: 438 IKAEKAEITRFFQKP-----KTPQAPKTLAGSCGKFAPFEIKEHMVLAPRRR 484
+A + ++P + P P+ AP E K H A R R
Sbjct: 517 EQAYLLSLQHDHRRPHPQHSQQPPPPQQERSKPSFHAP-EPKAHYEPADRAR 567
Score = 43.9 bits (102), Expect = 7e-04
Identities = 51/189 (26%), Positives = 89/189 (47%), Gaps = 34/189 (17%)
Query: 297 EGPPAPPKQHSSTSPF--PTSTPLRRITKK-------FVKGSTEKNKLRLQRDQERLGKQ 347
EG P H + F P + P R +KK F++G KN ++ + E+L K
Sbjct: 228 EGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQ-RPSTEQLLKH 286
Query: 348 LKLRAEREEKE---KLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEK---- 400
+R + E++ +LK+ R +++ +K E E E E E+ +++ +
Sbjct: 287 PFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNV 346
Query: 401 ----------QRLKEERRKERQEALEAK--LEEK--RKKEEEKR--LREEEKRIKAEKAE 444
RL++E KER EAL + L+E+ R++EE KR L E +KRI+ +K +
Sbjct: 347 PGESTLRRDFLRLQQEN-KERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQ 405
Query: 445 ITRFFQKPK 453
R ++ +
Sbjct: 406 RRRLEEQQR 414
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.130 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,474,746
Number of Sequences: 37866
Number of extensions: 2481738
Number of successful extensions: 92111
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1518
Number of HSP's successfully gapped in prelim test: 1275
Number of HSP's that attempted gapping in prelim test: 19986
Number of HSP's gapped (non-prelim): 29343
length of query: 956
length of database: 18,247,518
effective HSP length: 112
effective length of query: 844
effective length of database: 14,006,526
effective search space: 11821507944
effective search space used: 11821507944
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.