Search of human proteins with 5031947

Search of human proteins with 5031947

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5031947 nitrilase 1 [Homo sapiens]
         (327 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5031947 nitrilase 1 [Homo sapiens]                                 677   0.0  
gi|9910460 nitrilase family, member 2 [Homo sapiens]                  185   4e-47
gi|7706509 beta-ureidopropionase [Homo sapiens]                        63   3e-10
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]       39   0.006
gi|17865816 vanin 2 isoform 2 [Homo sapiens]                           34   0.16 
gi|17865814 vanin 2 isoform 1 precursor [Homo sapiens]                 34   0.16 
gi|223633991 vanin 1 precursor [Homo sapiens]                          33   0.26 
gi|66932888 vanin 3 isoform 1 precursor [Homo sapiens]                 33   0.35 
gi|169217659 PREDICTED: similar to ectonucleotide pyrophosphatas...    32   0.77 
gi|169167316 PREDICTED: similar to ectonucleotide pyrophosphatas...    32   0.77 
gi|21361458 Rho guanine nucleotide exchange factor (GEF) 17 [Hom...    30   2.2  
gi|226529806 histone deacetylase 10 isoform 2 [Homo sapiens]           29   6.5  
gi|20070354 histone deacetylase 10 isoform 1 [Homo sapiens]            29   6.5  
gi|157384998 low density lipoprotein receptor-related protein 4 ...    29   6.5  
gi|169213954 PREDICTED: similar to hCG2040171 [Homo sapiens]           28   8.5  
gi|239751793 PREDICTED: similar to hCG2040171 [Homo sapiens]           28   8.5  
gi|239746284 PREDICTED: similar to hCG2040171 [Homo sapiens]           28   8.5  
gi|28557777 immunoglobulin-like domain containing receptor 1 [Ho...    28   8.5  

>gi|5031947 nitrilase 1 [Homo sapiens]
          Length = 327

 Score =  677 bits (1748), Expect = 0.0
 Identities = 327/327 (100%), Positives = 327/327 (100%)

Query: 1   MLGFITRPPHRFLSLLCPGLRIPQLSVLCAQPRPRAMAISSSSCELPLVAVCQVTSTPDK 60
           MLGFITRPPHRFLSLLCPGLRIPQLSVLCAQPRPRAMAISSSSCELPLVAVCQVTSTPDK
Sbjct: 1   MLGFITRPPHRFLSLLCPGLRIPQLSVLCAQPRPRAMAISSSSCELPLVAVCQVTSTPDK 60

Query: 61  QQNFKTCAELVREAARLGACLAFLPEAFDFIARDPAETLHLSEPLGGKLLEEYTQLAREC 120
           QQNFKTCAELVREAARLGACLAFLPEAFDFIARDPAETLHLSEPLGGKLLEEYTQLAREC
Sbjct: 61  QQNFKTCAELVREAARLGACLAFLPEAFDFIARDPAETLHLSEPLGGKLLEEYTQLAREC 120

Query: 121 GLWLSLGGFHERGQDWEQTQKIYNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNS 180
           GLWLSLGGFHERGQDWEQTQKIYNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNS
Sbjct: 121 GLWLSLGGFHERGQDWEQTQKIYNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNS 180

Query: 181 TMPGPSLESPVSTPAGKIGLAVCYDMRFPELSLALAQAGAEILTYPSAFGSITGPAHWEV 240
           TMPGPSLESPVSTPAGKIGLAVCYDMRFPELSLALAQAGAEILTYPSAFGSITGPAHWEV
Sbjct: 181 TMPGPSLESPVSTPAGKIGLAVCYDMRFPELSLALAQAGAEILTYPSAFGSITGPAHWEV 240

Query: 241 LLRARAIETQCYVVAAAQCGRHHEKRASYGHSMVVDPWGTVVARCSEGPGLCLARIDLNY 300
           LLRARAIETQCYVVAAAQCGRHHEKRASYGHSMVVDPWGTVVARCSEGPGLCLARIDLNY
Sbjct: 241 LLRARAIETQCYVVAAAQCGRHHEKRASYGHSMVVDPWGTVVARCSEGPGLCLARIDLNY 300

Query: 301 LRQLRRHLPVFQHRRPDLYGNLGHPLS 327
           LRQLRRHLPVFQHRRPDLYGNLGHPLS
Sbjct: 301 LRQLRRHLPVFQHRRPDLYGNLGHPLS 327


>gi|9910460 nitrilase family, member 2 [Homo sapiens]
          Length = 276

 Score =  185 bits (470), Expect = 4e-47
 Identities = 100/274 (36%), Positives = 152/274 (55%), Gaps = 13/274 (4%)

Query: 49  VAVCQVTSTPDKQQNFKTCAELVREAARLGACLAFLPEAFDFIARDPAETLHL---SEPL 105
           +A+ Q+  +  K  N       +REAA  GA +  LPE F+     P    +    +E +
Sbjct: 6   LALIQLQISSIKSDNVTRACSFIREAATQGAKIVSLPECFN----SPYGAKYFPEYAEKI 61

Query: 106 GGKLLEEYTQLARECGLWLSLGGFHERGQDWEQTQKIYNCHVLLNSKGAVVATYRKTHLC 165
            G+  ++ +++A+EC ++L  G   E     E   K+YN   +    G ++A YRK HL 
Sbjct: 62  PGESTQKLSEVAKECSIYLIGGSIPE-----EDAGKLYNTCAVFGPDGTLLAKYRKIHLF 116

Query: 166 DVEIPGQGPMCESNSTMPGPSLESPVSTPAGKIGLAVCYDMRFPELSLALAQAGAEILTY 225
           D+++PG+    ES +  PG S  S   TP  ++GL +CYDMRF EL+   AQ G ++L Y
Sbjct: 117 DIDVPGKITFQESKTLSPGDSF-STFDTPYCRVGLGICYDMRFAELAQIYAQRGCQLLVY 175

Query: 226 PSAFGSITGPAHWEVLLRARAIETQCYVVAAAQCGRHHEKRASYGHSMVVDPWGTVVARC 285
           P AF   TGPAHWE+L R+RA++ Q YV  A+          ++GHS VV+PWG V+A+ 
Sbjct: 176 PGAFNLTTGPAHWELLQRSRAVDNQVYVATASPARDDKASYVAWGHSTVVNPWGEVLAKA 235

Query: 286 SEGPGLCLARIDLNYLRQLRRHLPVFQHRRPDLY 319
                +  + IDL  L ++R+ +PVF+ +R DLY
Sbjct: 236 GTEEAIVYSDIDLKKLAEIRQQIPVFRQKRSDLY 269


>gi|7706509 beta-ureidopropionase [Homo sapiens]
          Length = 384

 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 57/188 (30%), Positives = 82/188 (43%), Gaps = 23/188 (12%)

Query: 134 QDWEQTQKIYNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNSTMPGPSLESPV-S 192
           +D E    ++N  V++++ GAV+   RK H     IP  G   ES   M G +L  PV  
Sbjct: 169 RDSEHGDVLWNTAVVISNSGAVLGKTRKNH-----IPRVGDFNESTYYMEG-NLGHPVFQ 222

Query: 193 TPAGKIGLAVCYDMRFPELSLALAQAGAEILTYPSAFGSITGPAHWEVLLRARAIETQCY 252
           T  G+I + +CY    P   L  +  GAEI+  PSA       + W +  R  AI   C+
Sbjct: 223 TQFGRIAVNICYGRHHPLNWLMYSINGAEIIFNPSATIGALSESLWPIEARNAAIANHCF 282

Query: 253 VVAAAQCGRHH---------EKRAS------YGHSMVVDPWGTVVARCSEG-PGLCLARI 296
             A  + G  H          K+A       YG S V  P  +     S    GL +A++
Sbjct: 283 TCAINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKL 342

Query: 297 DLNYLRQL 304
           DLN  +Q+
Sbjct: 343 DLNLCQQV 350


>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
          Length = 2240

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 36/151 (23%), Positives = 64/151 (42%), Gaps = 14/151 (9%)

Query: 63   NFKTCAELVREAARLGACLAFLPEAFDFIARDPAETLHLSEPLGGKLLEEYT-QLARECG 121
            N ++ A+ V +A  +  C       FD+++ D  +T+H+   +  K + +Y  +L     
Sbjct: 1062 NMQSVAKFVTKAYPVSGC-------FDYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVS 1114

Query: 122  LWLSLGGFHERGQDWEQTQKIYNCHVLLNSKGAVVATYRKTHLCD---VEIPGQGPMCES 178
              L L  FH   ++ E        +     +  VVA   + H+ D   + +  Q P+   
Sbjct: 1115 KELCLIRFHPATEEEEVAYISLYSYFSSRGRFGVVANNNR-HVKDLYLIPLSAQDPVPSK 1173

Query: 179  NSTMPGPSLESPVSTPAGKIGLAVCYDMRFP 209
                 GP LESP   P   +GL +C  ++ P
Sbjct: 1174 LLPFEGPGLESP--RPNIILGLVICQKIKRP 1202


>gi|17865816 vanin 2 isoform 2 [Homo sapiens]
          Length = 467

 Score = 34.3 bits (77), Expect = 0.16
 Identities = 22/91 (24%), Positives = 43/91 (47%), Gaps = 11/91 (12%)

Query: 143 YNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNSTMPGPSLESPVSTPAGKIGLAV 202
           YN +V+ N++G +VA Y K HL            E    +P        +T  G+ G+  
Sbjct: 108 YNTNVVYNTEGKLVARYHKYHL----------YSEPQFNVPEKPELVTFNTAFGRFGIFT 157

Query: 203 CYDMRFPELSLALAQ-AGAEILTYPSAFGSI 232
           C+D+ F +  + L +    + + +P+A+ ++
Sbjct: 158 CFDIFFYDPGVTLVKDFHVDTILFPTAWMNV 188


>gi|17865814 vanin 2 isoform 1 precursor [Homo sapiens]
          Length = 520

 Score = 34.3 bits (77), Expect = 0.16
 Identities = 22/91 (24%), Positives = 43/91 (47%), Gaps = 11/91 (12%)

Query: 143 YNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNSTMPGPSLESPVSTPAGKIGLAV 202
           YN +V+ N++G +VA Y K HL            E    +P        +T  G+ G+  
Sbjct: 161 YNTNVVYNTEGKLVARYHKYHL----------YSEPQFNVPEKPELVTFNTAFGRFGIFT 210

Query: 203 CYDMRFPELSLALAQ-AGAEILTYPSAFGSI 232
           C+D+ F +  + L +    + + +P+A+ ++
Sbjct: 211 CFDIFFYDPGVTLVKDFHVDTILFPTAWMNV 241


>gi|223633991 vanin 1 precursor [Homo sapiens]
          Length = 513

 Score = 33.5 bits (75), Expect = 0.26
 Identities = 22/91 (24%), Positives = 44/91 (48%), Gaps = 10/91 (10%)

Query: 143 YNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNSTMPGPSLESPVSTPAGKIGLAV 202
           YN  V+ +S+G +VA Y K +L          M E+   +P        +T  G  G+  
Sbjct: 160 YNTDVVFDSQGKLVARYHKQNLF---------MGENQFNVPKEPEIVTFNTTFGSFGIFT 210

Query: 203 CYDMRFPELSLALAQ-AGAEILTYPSAFGSI 232
           C+D+ F + ++ L +    + + +P+A+ ++
Sbjct: 211 CFDILFHDPAVTLVKDFHVDTIVFPTAWMNV 241


>gi|66932888 vanin 3 isoform 1 precursor [Homo sapiens]
          Length = 274

 Score = 33.1 bits (74), Expect = 0.35
 Identities = 30/109 (27%), Positives = 41/109 (37%), Gaps = 21/109 (19%)

Query: 143 YNCHVLLNSKGAVVATYRKTHLCDVEIPGQGPMCESNSTMPGPSLESPVSTPAGKIGLAV 202
           YN  V+ +S+G ++A Y K +L   EI    P      T           TP GK G+  
Sbjct: 161 YNTDVVFDSQGKLLARYHKYNLFAPEIQFDFPKDSELVTF---------DTPFGKFGIFT 211

Query: 203 CYDM-----------RFPELSLALAQAGAEILTYPSAFGSIT-GPAHWE 239
           C+D+            F   + +  Q G         F SI  GP  WE
Sbjct: 212 CFDIFSHDPAVVVVDEFQLTAFSTPQHGTTRCPSSRLFPSIQHGPRPWE 260


>gi|169217659 PREDICTED: similar to ectonucleotide
           pyrophosphatase/phosphodiesterase 5 [Homo sapiens]
          Length = 542

 Score = 32.0 bits (71), Expect = 0.77
 Identities = 16/38 (42%), Positives = 19/38 (50%), Gaps = 1/38 (2%)

Query: 170 PGQGPMCESNSTMPGPSLESP-VSTPAGKIGLAVCYDM 206
           P  GP  E +   PGPS   P +  P     LAVCYD+
Sbjct: 267 PAPGPASEDHGLAPGPSSNPPQLRLPESAHRLAVCYDI 304


>gi|169167316 PREDICTED: similar to ectonucleotide
           pyrophosphatase/phosphodiesterase 5 [Homo sapiens]
          Length = 542

 Score = 32.0 bits (71), Expect = 0.77
 Identities = 16/38 (42%), Positives = 19/38 (50%), Gaps = 1/38 (2%)

Query: 170 PGQGPMCESNSTMPGPSLESP-VSTPAGKIGLAVCYDM 206
           P  GP  E +   PGPS   P +  P     LAVCYD+
Sbjct: 267 PAPGPASEDHGLAPGPSSNPPQLRLPESAHRLAVCYDI 304


>gi|21361458 Rho guanine nucleotide exchange factor (GEF) 17 [Homo
            sapiens]
          Length = 2063

 Score = 30.4 bits (67), Expect = 2.2
 Identities = 23/78 (29%), Positives = 31/78 (39%), Gaps = 3/78 (3%)

Query: 154  AVVATYRKTHLCDVEIPGQGPMCESNSTMPGPSLESPVSTPAGKIGLAVCYDMRFPELSL 213
            A +A      LC   +PG  P C      P PSL SP  T     G  +  +    E + 
Sbjct: 1541 ACIAVCSARILCIGAVPGLQPRCHRE---PPPSLRSPPETAPEPAGPELDVEAAADEEAA 1597

Query: 214  ALAQAGAEILTYPSAFGS 231
             LA+ G +   + S  GS
Sbjct: 1598 TLAEPGPQPCLHISIAGS 1615


>gi|226529806 histone deacetylase 10 isoform 2 [Homo sapiens]
          Length = 649

 Score = 28.9 bits (63), Expect = 6.5
 Identities = 15/47 (31%), Positives = 27/47 (57%), Gaps = 3/47 (6%)

Query: 169 IPGQGPMCESNSTMPGPSLESPVSTPAGKIGLAVCYDMRFPELSLAL 215
           +PG GP+C++ ++ P   L+ P   PA  +  AV   +  P+++L L
Sbjct: 362 LPG-GPVCKAAASAPSSLLDQPCLCPAPSVRTAVA--LTTPDITLVL 405


>gi|20070354 histone deacetylase 10 isoform 1 [Homo sapiens]
          Length = 669

 Score = 28.9 bits (63), Expect = 6.5
 Identities = 15/47 (31%), Positives = 27/47 (57%), Gaps = 3/47 (6%)

Query: 169 IPGQGPMCESNSTMPGPSLESPVSTPAGKIGLAVCYDMRFPELSLAL 215
           +PG GP+C++ ++ P   L+ P   PA  +  AV   +  P+++L L
Sbjct: 382 LPG-GPVCKAAASAPSSLLDQPCLCPAPSVRTAVA--LTTPDITLVL 425


>gi|157384998 low density lipoprotein receptor-related protein 4 [Homo
            sapiens]
          Length = 1905

 Score = 28.9 bits (63), Expect = 6.5
 Identities = 24/80 (30%), Positives = 33/80 (41%), Gaps = 6/80 (7%)

Query: 32   PRPRAMAISSSSCELPLVAVCQVTSTPDKQQNFKTCAE--LVREAARLGACLAFLPEAFD 89
            P PRA  +S  S  LP      + S+  + +      E       ARLG C      + D
Sbjct: 1657 PAPRATGMSEKSPVLPNTPPTTLYSSTTRTRTSLEEVEGRCSERDARLGLCA----RSND 1712

Query: 90   FIARDPAETLHLSEPLGGKL 109
             +   P E LH+S  +GG L
Sbjct: 1713 AVPAAPGEGLHISYAIGGLL 1732


>gi|169213954 PREDICTED: similar to hCG2040171 [Homo sapiens]
          Length = 354

 Score = 28.5 bits (62), Expect = 8.5
 Identities = 12/30 (40%), Positives = 17/30 (56%)

Query: 206 MRFPELSLALAQAGAEILTYPSAFGSITGP 235
           + +P L +A A  G+ +L  PS FG   GP
Sbjct: 129 VNYPLLDMAAAATGSPLLLTPSPFGGAPGP 158


>gi|239751793 PREDICTED: similar to hCG2040171 [Homo sapiens]
          Length = 354

 Score = 28.5 bits (62), Expect = 8.5
 Identities = 12/30 (40%), Positives = 17/30 (56%)

Query: 206 MRFPELSLALAQAGAEILTYPSAFGSITGP 235
           + +P L +A A  G+ +L  PS FG   GP
Sbjct: 129 VNYPLLDMAAAATGSPLLLTPSPFGGAPGP 158


>gi|239746284 PREDICTED: similar to hCG2040171 [Homo sapiens]
          Length = 354

 Score = 28.5 bits (62), Expect = 8.5
 Identities = 12/30 (40%), Positives = 17/30 (56%)

Query: 206 MRFPELSLALAQAGAEILTYPSAFGSITGP 235
           + +P L +A A  G+ +L  PS FG   GP
Sbjct: 129 VNYPLLDMAAAATGSPLLLTPSPFGGAPGP 158


>gi|28557777 immunoglobulin-like domain containing receptor 1 [Homo
           sapiens]
          Length = 502

 Score = 28.5 bits (62), Expect = 8.5
 Identities = 14/30 (46%), Positives = 17/30 (56%)

Query: 298 LNYLRQLRRHLPVFQHRRPDLYGNLGHPLS 327
           L YL +  R+L + Q   PDL G  GHP S
Sbjct: 242 LEYLEKELRNLNLAQPLPPDLKGRFGHPCS 271


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,764,848
Number of Sequences: 37866
Number of extensions: 696219
Number of successful extensions: 1653
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1641
Number of HSP's gapped (non-prelim): 18
length of query: 327
length of database: 18,247,518
effective HSP length: 103
effective length of query: 224
effective length of database: 14,347,320
effective search space: 3213799680
effective search space used: 3213799680
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.