Search of human proteins with 5031777

Search of human proteins with 5031777

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5031777 isocitrate dehydrogenase 3 (NAD+) alpha precursor
[Homo sapiens]
         (366 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5031777 isocitrate dehydrogenase 3 (NAD+) alpha precursor [Ho...   737   0.0  
gi|28178816 isocitrate dehydrogenase 3, beta subunit isoform b p...   285   3e-77
gi|28178821 isocitrate dehydrogenase 3, beta subunit isoform a p...   278   4e-75
gi|4758582 isocitrate dehydrogenase 3 (NAD+) gamma isoform a pre...   276   3e-74
gi|28178838 isocitrate dehydrogenase 3 (NAD+) gamma isoform b pr...   262   3e-70
gi|28178819 isocitrate dehydrogenase 3, beta subunit isoform c [...   189   4e-48
gi|28178832 isocitrate dehydrogenase 2 (NADP+), mitochondrial pr...    41   0.001
gi|110349719 titin isoform N2-A [Homo sapiens]                         31   2.0  
gi|110349717 titin isoform novex-2 [Homo sapiens]                      31   2.0  
gi|110349713 titin isoform novex-1 [Homo sapiens]                      31   2.0  
gi|110349715 titin isoform N2-B [Homo sapiens]                         31   2.0  
gi|18375507 apurinic/apyrimidinic endonuclease 2 [Homo sapiens]        30   3.4  
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H...    30   4.5  
gi|4758822 nephrin precursor [Homo sapiens]                            30   4.5  
gi|117606347 F-box protein 43 isoform a [Homo sapiens]                 28   9.9  
gi|117606351 F-box protein 43 isoform b [Homo sapiens]                 28   9.9  
gi|27262622 neuron navigator 1 [Homo sapiens]                          28   9.9  

>gi|5031777 isocitrate dehydrogenase 3 (NAD+) alpha precursor [Homo
           sapiens]
          Length = 366

 Score =  737 bits (1903), Expect = 0.0
 Identities = 366/366 (100%), Positives = 366/366 (100%)

Query: 1   MAGPAWISKVSRLLGAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKAP 60
           MAGPAWISKVSRLLGAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKAP
Sbjct: 1   MAGPAWISKVSRLLGAFHNPKQVTRGFTGGVQTVTLIPGDGIGPEISAAVMKIFDAAKAP 60

Query: 61  IQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDL 120
           IQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDL
Sbjct: 61  IQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDL 120

Query: 121 YANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIA 180
           YANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIA
Sbjct: 121 YANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIA 180

Query: 181 EFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMV 240
           EFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMV
Sbjct: 181 EFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMV 240

Query: 241 QDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKD 300
           QDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKD
Sbjct: 241 QDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKD 300

Query: 301 MANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICR 360
           MANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICR
Sbjct: 301 MANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICR 360

Query: 361 RVKDLD 366
           RVKDLD
Sbjct: 361 RVKDLD 366


>gi|28178816 isocitrate dehydrogenase 3, beta subunit isoform b
           precursor [Homo sapiens]
          Length = 383

 Score =  285 bits (730), Expect = 3e-77
 Identities = 150/328 (45%), Positives = 213/328 (64%), Gaps = 5/328 (1%)

Query: 34  VTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESMDKNKM 93
           VT++PGDG+GPE+  AV ++F AA  P++++E +++ +Q    +  +  +   SM +NK+
Sbjct: 51  VTMLPGDGVGPELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKL-EQVLSSMKENKV 109

Query: 94  GLKGPLKTPIA--AGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEG 151
            + G + TP+       S ++ LR+  DL+ANV    S+ GY T + ++++V IRE TEG
Sbjct: 110 AIIGKIHTPMEYKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEG 169

Query: 152 EYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLF 211
           EYS +EH    GV++ +K++T   S+RIA+FAF+YA    R  VTAVHKANIM++ DGLF
Sbjct: 170 EYSSLEHESARGVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLF 229

Query: 212 LQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLG 271
           LQ C EVAE    IKF  M +D  C+ +VQ+P QFDVLVMPNLYG+I+ +L AGL+GG G
Sbjct: 230 LQCCEEVAELYPKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAG 289

Query: 272 VTPSGNIGANGVAIFES-VHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAA 330
           V P  +  A   A+FE+          G+++ANPTA+LLSA  MLRH+ L  H++ I  A
Sbjct: 290 VVPGESYSAE-YAVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADA 348

Query: 331 CFATIKDGKSLTKDLGGNAKCSDFTEEI 358
               IK GK  T D+GG A C DFTE +
Sbjct: 349 VKKVIKVGKVRTSDMGGYATCHDFTEAV 376


>gi|28178821 isocitrate dehydrogenase 3, beta subunit isoform a
           precursor [Homo sapiens]
          Length = 385

 Score =  278 bits (712), Expect = 4e-75
 Identities = 146/328 (44%), Positives = 213/328 (64%), Gaps = 5/328 (1%)

Query: 34  VTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESMDKNKM 93
           VT++PGDG+GPE+  AV ++F AA  P++++E +++ +Q    +  +  +   SM +NK+
Sbjct: 51  VTMLPGDGVGPELMHAVKEVFKAAAVPVEFQEHHLSEVQNMASEEKL-EQVLSSMKENKV 109

Query: 94  GLKGPLKTPIA--AGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEG 151
            + G + TP+       S ++ LR+  DL+ANV    S+ GY T + ++++V IRE TEG
Sbjct: 110 AIIGKIHTPMEYKGELASYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEG 169

Query: 152 EYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLF 211
           EYS +EH    GV++ +K++T   S+RIA+FAF+YA    R  VTAVHKANIM++ DGLF
Sbjct: 170 EYSSLEHESARGVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLF 229

Query: 212 LQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLG 271
           LQ C EVAE    IKF  M +D  C+ +VQ+P QFDVLVMPNLYG+I+ +L AGL+GG G
Sbjct: 230 LQCCEEVAELYPKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAG 289

Query: 272 VTPSGNIGANGVAIFES-VHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAA 330
           V P  +  A   A+FE+          G+++ANPTA+LLSA  MLRH+ L  H++ I  A
Sbjct: 290 VVPGESYSAE-YAVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADA 348

Query: 331 CFATIKDGKSLTKDLGGNAKCSDFTEEI 358
               IK GK  T+D+GG +  +DF + +
Sbjct: 349 VKKVIKVGKVRTRDMGGYSTTTDFIKSV 376


>gi|4758582 isocitrate dehydrogenase 3 (NAD+) gamma isoform a
           precursor [Homo sapiens]
          Length = 393

 Score =  276 bits (705), Expect = 3e-74
 Identities = 156/372 (41%), Positives = 225/372 (60%), Gaps = 16/372 (4%)

Query: 3   GPAWISKVSRLLGAFHNPKQ--------VTRGFTGGVQTVTLIPGDGIGPEISAAVMKIF 54
           GPA + +   +LGA   P +              GG  TVT+IPGDGIGPE+   V  +F
Sbjct: 18  GPALLCRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVF 77

Query: 55  DAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTP--IAAGHPSMNL 112
             A  P+ +EE +V++             A  ++ +N++ LKG ++T   +   H S N 
Sbjct: 78  RHACVPVDFEEVHVSSNADEEDI----RNAIMAIRRNRVALKGNIETNHNLPPSHKSRNN 133

Query: 113 LLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLIT 172
           +LR + DLYANV  C S+ G  T + D++I+ +RENTEGEYS +EH  V GVV+S+K+IT
Sbjct: 134 ILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIIT 193

Query: 173 EGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYL 232
           +  S RIAE+AF+ A+ + R  VTAVHKANIM++ DGLFLQ CREVA     I F  M +
Sbjct: 194 KAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIV 253

Query: 233 DTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFE-SVHG 291
           D   + +V  P QFDV+VMPNLYG+I++++CAGL+GG G+    N G +  A+FE +   
Sbjct: 254 DNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYG-HVYAVFETATRN 312

Query: 292 TAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKC 351
           T   IA K++ANPTA LL++ MML H+ L  +A  I  A  A++ +    T D+GG    
Sbjct: 313 TGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASMDNENMHTPDIGGQGTT 372

Query: 352 SDFTEEICRRVK 363
           S+  +++ R ++
Sbjct: 373 SEAIQDVIRHIR 384


>gi|28178838 isocitrate dehydrogenase 3 (NAD+) gamma isoform b
           precursor [Homo sapiens]
          Length = 380

 Score =  262 bits (670), Expect = 3e-70
 Identities = 150/344 (43%), Positives = 211/344 (61%), Gaps = 16/344 (4%)

Query: 3   GPAWISKVSRLLGAFHNPKQ--------VTRGFTGGVQTVTLIPGDGIGPEISAAVMKIF 54
           GPA + +   +LGA   P +              GG  TVT+IPGDGIGPE+   V  +F
Sbjct: 18  GPALLCRPWEVLGAHEVPSRNIFSEQTIPPSAKYGGRHTVTMIPGDGIGPELMLHVKSVF 77

Query: 55  DAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESMDKNKMGLKGPLKTP--IAAGHPSMNL 112
             A  P+ +EE +V++             A  ++ +N++ LKG ++T   +   H S N 
Sbjct: 78  RHACVPVDFEEVHVSSNADEEDI----RNAIMAIRRNRVALKGNIETNHNLPPSHKSRNN 133

Query: 113 LLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLIT 172
           +LR + DLYANV  C S+ G  T + D++I+ +RENTEGEYS +EH  V GVV+S+K+IT
Sbjct: 134 ILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYSSLEHESVAGVVESLKIIT 193

Query: 173 EGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYL 232
           +  S RIAE+AF+ A+ + R  VTAVHKANIM++ DGLFLQ CREVA     I F  M +
Sbjct: 194 KAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVAARYPQITFENMIV 253

Query: 233 DTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFE-SVHG 291
           D   + +V  P QFDV+VMPNLYG+I++++CAGL+GG G+    N G +  A+FE +   
Sbjct: 254 DNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYG-HVYAVFETATRN 312

Query: 292 TAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATI 335
           T   IA K++ANPTA LL++ MML H+ L  +A  I  A  A++
Sbjct: 313 TGKSIANKNIANPTATLLASCMMLDHLKLHSYATSIRKAVLASM 356


>gi|28178819 isocitrate dehydrogenase 3, beta subunit isoform c
           [Homo sapiens]
          Length = 233

 Score =  189 bits (479), Expect = 4e-48
 Identities = 98/197 (49%), Positives = 132/197 (67%), Gaps = 2/197 (1%)

Query: 163 GVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESC 222
           GV++ +K++T   S+RIA+FAF+YA    R  VTAVHKANIM++ DGLFLQ C EVAE  
Sbjct: 29  GVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELY 88

Query: 223 KDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANG 282
             IKF  M +D  C+ +VQ+P QFDVLVMPNLYG+I+ +L AGL+GG GV P  +  A  
Sbjct: 89  PKIKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAE- 147

Query: 283 VAIFES-VHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSL 341
            A+FE+          G+++ANPTA+LLSA  MLRH+ L  H++ I  A    IK GK  
Sbjct: 148 YAVFETGARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVR 207

Query: 342 TKDLGGNAKCSDFTEEI 358
           T+D+GG +  +DF + +
Sbjct: 208 TRDMGGYSTTTDFIKSV 224


>gi|28178832 isocitrate dehydrogenase 2 (NADP+), mitochondrial
           precursor [Homo sapiens]
          Length = 452

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 43/169 (25%), Positives = 68/169 (40%), Gaps = 23/169 (13%)

Query: 200 KANIMRMSDGLFLQKCREVAESCKDIKFNE-------MYLDTVCLNMVQDPSQFDVLVMP 252
           K  I++  DG F    +E+ +      F++         +D +   +++    F V    
Sbjct: 251 KNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGF-VWACK 309

Query: 253 NLYGDILSDLCAGLIGGLGVTPSGNIGANGVAI-FESVHGTAP------DIAGKDMANPT 305
           N  GD+ SD+ A   G LG+  S  +  +G  I  E+ HGT                NP 
Sbjct: 310 NYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPI 369

Query: 306 ALLLSAVMMLRHMGLFD-------HAARIEAACFATIKDGKSLTKDLGG 347
           A + +    L H G  D        A  +E  C  T++ G ++TKDL G
Sbjct: 370 ASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESG-AMTKDLAG 417


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 30.8 bits (68), Expect = 2.0
 Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 3/67 (4%)

Query: 38    PGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKW-MIPSEAKESMDK--NKMG 94
             P D  G EI+  V+   DA++   +WEE   TA++   G W +IP+   E   +  NK G
Sbjct: 15521 PLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYG 15580

Query: 95    LKGPLKT 101
             +    K+
Sbjct: 15581 ISDECKS 15587


>gi|110349717 titin isoform novex-2 [Homo sapiens]
          Length = 27118

 Score = 30.8 bits (68), Expect = 2.0
 Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 3/67 (4%)

Query: 38   PGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKW-MIPSEAKESMDK--NKMG 94
            P D  G EI+  V+   DA++   +WEE   TA++   G W +IP+   E   +  NK G
Sbjct: 9216 PLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYG 9275

Query: 95   LKGPLKT 101
            +    K+
Sbjct: 9276 ISDECKS 9282


>gi|110349713 titin isoform novex-1 [Homo sapiens]
          Length = 27051

 Score = 30.8 bits (68), Expect = 2.0
 Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 3/67 (4%)

Query: 38   PGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKW-MIPSEAKESMDK--NKMG 94
            P D  G EI+  V+   DA++   +WEE   TA++   G W +IP+   E   +  NK G
Sbjct: 9149 PLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYG 9208

Query: 95   LKGPLKT 101
            +    K+
Sbjct: 9209 ISDECKS 9215


>gi|110349715 titin isoform N2-B [Homo sapiens]
          Length = 26926

 Score = 30.8 bits (68), Expect = 2.0
 Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 3/67 (4%)

Query: 38   PGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKW-MIPSEAKESMDK--NKMG 94
            P D  G EI+  V+   DA++   +WEE   TA++   G W +IP+   E   +  NK G
Sbjct: 9024 PLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYG 9083

Query: 95   LKGPLKT 101
            +    K+
Sbjct: 9084 ISDECKS 9090


>gi|18375507 apurinic/apyrimidinic endonuclease 2 [Homo sapiens]
          Length = 518

 Score = 30.0 bits (66), Expect = 3.4
 Identities = 21/68 (30%), Positives = 30/68 (44%), Gaps = 7/68 (10%)

Query: 44  PEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESMDKN----KMGLKGPL 99
           P+I    + +  A   P   EE+ V  +     K    SEAK+  +      K  L GPL
Sbjct: 408 PDIELPSLPLMSALMTPKTPEEKAVAKVVKGQAK---TSEAKDEKELRTSFWKSVLAGPL 464

Query: 100 KTPIAAGH 107
           +TP+  GH
Sbjct: 465 RTPLCGGH 472


>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
           sapiens]
          Length = 1251

 Score = 29.6 bits (65), Expect = 4.5
 Identities = 15/63 (23%), Positives = 32/63 (50%), Gaps = 8/63 (12%)

Query: 31  VQTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESMDK 90
           VQT++++PG  + P++      + +  + P  WE+ +      P G  ++P+  +E+   
Sbjct: 289 VQTISILPGGQVEPDL------VLEEVEPP--WEDAHQDVSTSPQGTEVVPAYEEENKAV 340

Query: 91  NKM 93
            KM
Sbjct: 341 EKM 343


>gi|4758822 nephrin precursor [Homo sapiens]
          Length = 1241

 Score = 29.6 bits (65), Expect = 4.5
 Identities = 25/109 (22%), Positives = 47/109 (43%), Gaps = 14/109 (12%)

Query: 152 EYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVT-----------AVHK 200
           E+ G + ++V  V Q   L+    S   A  AF +    +R +             A+H 
Sbjct: 647 EFLGEQVLVVTAVEQGEALLPVSVSANPAPEAFNWTFRGYRLSPAGGPRHRILSSGALHL 706

Query: 201 ANIMRMSDGLFLQKCREVAESCK-DIKFNEMYLDTVCLNMVQDPSQFDV 248
            N+ R  DGL+   C+    + +  ++ +  Y  T+    +QDP++ +V
Sbjct: 707 WNVTRADDGLYQLHCQNSEGTAEARLRLDVHYAPTI--RALQDPTEVNV 753


>gi|117606347 F-box protein 43 isoform a [Homo sapiens]
          Length = 674

 Score = 28.5 bits (62), Expect = 9.9
 Identities = 53/244 (21%), Positives = 90/244 (36%), Gaps = 32/244 (13%)

Query: 75  GGKWMIPSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYK 134
           G K   P+   E  + + +GL  PL++P         +L RK  D    +     I G K
Sbjct: 61  GKKEKGPTLLYEHPETSGLGLTHPLESPT---QKKKCILPRKEKDKTPELCETPKISGKK 117

Query: 135 T---PYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYAR-NN 190
                  +V+   ++ + E + S +E      + Q I L      K I   A  ++R NN
Sbjct: 118 CLPRRRLNVSFALLKGDFESQNSSLE----SSISQVINL-----EKNIPSSASGFSRANN 168

Query: 191 HRSNVTAVHKAN-IMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVL 249
               VT+  K   +   S  L L   ++   +  D K +    +  C++ +Q  +  D +
Sbjct: 169 FSPLVTSTLKTEEVTSCSQKLRLNFSQQKTSTIDDSKDDCSLFEVECISPIQGNNFKDSI 228

Query: 250 V---------------MPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAP 294
                            P L G  +S    G    + VTP  N+ AN       +   +P
Sbjct: 229 THDFSDSSLCINDENACPELLGSSVSGTTCGTDEDIFVTPISNLVANIRFNASQILSPSP 288

Query: 295 DIAG 298
           ++ G
Sbjct: 289 EVRG 292


>gi|117606351 F-box protein 43 isoform b [Homo sapiens]
          Length = 708

 Score = 28.5 bits (62), Expect = 9.9
 Identities = 53/244 (21%), Positives = 90/244 (36%), Gaps = 32/244 (13%)

Query: 75  GGKWMIPSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYK 134
           G K   P+   E  + + +GL  PL++P         +L RK  D    +     I G K
Sbjct: 95  GKKEKGPTLLYEHPETSGLGLTHPLESPT---QKKKCILPRKEKDKTPELCETPKISGKK 151

Query: 135 T---PYTDVNIVTIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYAR-NN 190
                  +V+   ++ + E + S +E      + Q I L      K I   A  ++R NN
Sbjct: 152 CLPRRRLNVSFALLKGDFESQNSSLE----SSISQVINL-----EKNIPSSASGFSRANN 202

Query: 191 HRSNVTAVHKAN-IMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVL 249
               VT+  K   +   S  L L   ++   +  D K +    +  C++ +Q  +  D +
Sbjct: 203 FSPLVTSTLKTEEVTSCSQKLRLNFSQQKTSTIDDSKDDCSLFEVECISPIQGNNFKDSI 262

Query: 250 V---------------MPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAP 294
                            P L G  +S    G    + VTP  N+ AN       +   +P
Sbjct: 263 THDFSDSSLCINDENACPELLGSSVSGTTCGTDEDIFVTPISNLVANIRFNASQILSPSP 322

Query: 295 DIAG 298
           ++ G
Sbjct: 323 EVRG 326


>gi|27262622 neuron navigator 1 [Homo sapiens]
          Length = 1874

 Score = 28.5 bits (62), Expect = 9.9
 Identities = 21/52 (40%), Positives = 26/52 (50%), Gaps = 5/52 (9%)

Query: 58  KAPIQWEERNVTAIQGPG-GKWMIPSEAKESMDKNKMGLKGPLKTPIAAGHP 108
           KAP + E  + +    PG  KW    E  ES D +  G  G LK PI+ GHP
Sbjct: 479 KAPKKLEYDSGSLKMEPGTSKWR--RERPESCDDSSKG--GELKKPISLGHP 526


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,498,673
Number of Sequences: 37866
Number of extensions: 580251
Number of successful extensions: 1431
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1413
Number of HSP's gapped (non-prelim): 22
length of query: 366
length of database: 18,247,518
effective HSP length: 104
effective length of query: 262
effective length of database: 14,309,454
effective search space: 3749076948
effective search space used: 3749076948
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.