Search of human proteins with 4826661

Search of human proteins with 4826661

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4826661 constitutive androstane receptor isoform 3 [Homo
sapiens]
         (348 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4826661 constitutive androstane receptor isoform 3 [Homo sapi...   703   0.0  
gi|117938752 constitutive androstane receptor isoform 2 [Homo sa...   697   0.0  
gi|117938756 constitutive androstane receptor isoform 1 [Homo sa...   691   0.0  
gi|117938750 constitutive androstane receptor isoform 10 [Homo s...   626   e-180
gi|117938736 constitutive androstane receptor isoform 9 [Homo sa...   620   e-178
gi|117938746 constitutive androstane receptor isoform 7 [Homo sa...   616   e-177
gi|117938729 constitutive androstane receptor isoform 6 [Homo sa...   616   e-176
gi|117938754 constitutive androstane receptor isoform 4 [Homo sa...   610   e-175
gi|117938734 constitutive androstane receptor isoform 5 [Homo sa...   607   e-174
gi|117938748 constitutive androstane receptor isoform 14 [Homo s...   545   e-155
gi|117938744 constitutive androstane receptor isoform 13 [Homo s...   539   e-153
gi|117938738 constitutive androstane receptor isoform 12 [Homo s...   533   e-152
gi|117938732 constitutive androstane receptor isoform 11 [Homo s...   531   e-151
gi|117938740 constitutive androstane receptor isoform 8 [Homo sa...   526   e-150
gi|117938742 constitutive androstane receptor isoform 15 [Homo s...   450   e-126
gi|14702164 nuclear receptor subfamily 1, group I, member 2 isof...   299   3e-81
gi|11863132 nuclear receptor subfamily 1, group I, member 2 isof...   287   9e-78
gi|34398348 nuclear receptor subfamily 1, group I, member 2 isof...   287   9e-78
gi|194294519 nuclear receptor subfamily 1, group H, member 3 iso...   188   7e-48
gi|194294517 nuclear receptor subfamily 1, group H, member 3 iso...   188   7e-48
gi|85362735 nuclear receptor subfamily 1, group H, member 2 [Hom...   170   2e-42
gi|189491771 thyroid hormone receptor, beta [Homo sapiens]            169   3e-42
gi|189491769 thyroid hormone receptor, beta [Homo sapiens]            169   3e-42
gi|40806162 thyroid hormone receptor, beta [Homo sapiens]             169   3e-42
gi|4826980 nuclear receptor subfamily 1, group H, member 4 [Homo...   162   4e-40
gi|40806160 thyroid hormone receptor, alpha isoform 1 [Homo sapi...   162   4e-40
gi|20127452 thyroid hormone receptor, alpha isoform 2 [Homo sapi...   156   3e-38
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]   151   7e-37
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]    151   7e-37
gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]     151   7e-37

>gi|4826661 constitutive androstane receptor isoform 3 [Homo
           sapiens]
          Length = 348

 Score =  703 bits (1814), Expect = 0.0
 Identities = 348/348 (100%), Positives = 348/348 (100%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLE 240
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLE
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLE 240

Query: 241 LLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQ 300
           LLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQ
Sbjct: 241 LLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQ 300

Query: 301 RRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 348
           RRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
Sbjct: 301 RRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 348


>gi|117938752 constitutive androstane receptor isoform 2 [Homo
           sapiens]
          Length = 352

 Score =  697 bits (1799), Expect = 0.0
 Identities = 348/352 (98%), Positives = 348/352 (98%), Gaps = 4/352 (1%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR----VGFQV 236
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR    VGFQV
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240

Query: 237 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 296
           EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI
Sbjct: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 300

Query: 297 KGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 348
           KGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
Sbjct: 301 KGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 352


>gi|117938756 constitutive androstane receptor isoform 1 [Homo
           sapiens]
          Length = 357

 Score =  691 bits (1783), Expect = 0.0
 Identities = 348/357 (97%), Positives = 348/357 (97%), Gaps = 9/357 (2%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR----VGFQV 236
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR    VGFQV
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240

Query: 237 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP-----DRPGVTQRDEIDQLQEEMALT 291
           EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP     DRPGVTQRDEIDQLQEEMALT
Sbjct: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALT 300

Query: 292 LQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 348
           LQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
Sbjct: 301 LQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 357


>gi|117938750 constitutive androstane receptor isoform 10 [Homo
           sapiens]
          Length = 319

 Score =  626 bits (1615), Expect = e-180
 Identities = 313/313 (100%), Positives = 313/313 (100%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGV 275
           NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGV
Sbjct: 187 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGV 246

Query: 276 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQG 335
           TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQG
Sbjct: 247 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQG 306

Query: 336 LSAMMPLLQEICS 348
           LSAMMPLLQEICS
Sbjct: 307 LSAMMPLLQEICS 319


>gi|117938736 constitutive androstane receptor isoform 9 [Homo
           sapiens]
          Length = 324

 Score =  620 bits (1599), Expect = e-178
 Identities = 313/318 (98%), Positives = 313/318 (98%), Gaps = 5/318 (1%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP----- 270
           NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP     
Sbjct: 187 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLT 246

Query: 271 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQI 330
           DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQI
Sbjct: 247 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQI 306

Query: 331 QHIQGLSAMMPLLQEICS 348
           QHIQGLSAMMPLLQEICS
Sbjct: 307 QHIQGLSAMMPLLQEICS 324


>gi|117938746 constitutive androstane receptor isoform 7 [Homo
           sapiens]
          Length = 339

 Score =  616 bits (1589), Expect = e-177
 Identities = 306/310 (98%), Positives = 306/310 (98%), Gaps = 4/310 (1%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR----VGFQV 236
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR    VGFQV
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQV 240

Query: 237 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 296
           EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI
Sbjct: 241 EFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYI 300

Query: 297 KGQQRRPRDR 306
           KGQQRRPRDR
Sbjct: 301 KGQQRRPRDR 310


>gi|117938729 constitutive androstane receptor isoform 6 [Homo
           sapiens]
          Length = 340

 Score =  616 bits (1588), Expect = e-176
 Identities = 306/311 (98%), Positives = 306/311 (98%), Gaps = 5/311 (1%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLE 240
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLE
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLE 240

Query: 241 LLFHFHGTLRKLQLQEPEYVLLAAMALFSP-----DRPGVTQRDEIDQLQEEMALTLQSY 295
           LLFHFHGTLRKLQLQEPEYVLLAAMALFSP     DRPGVTQRDEIDQLQEEMALTLQSY
Sbjct: 241 LLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLTDRPGVTQRDEIDQLQEEMALTLQSY 300

Query: 296 IKGQQRRPRDR 306
           IKGQQRRPRDR
Sbjct: 301 IKGQQRRPRDR 311


>gi|117938754 constitutive androstane receptor isoform 4 [Homo
           sapiens]
          Length = 314

 Score =  610 bits (1572), Expect = e-175
 Identities = 310/348 (89%), Positives = 311/348 (89%), Gaps = 34/348 (9%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLE 240
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR         
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR--------- 231

Query: 241 LLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQ 300
                                    A +  DRPGVTQRDEIDQLQEEMALTLQSYIKGQQ
Sbjct: 232 -------------------------APYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQ 266

Query: 301 RRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 348
           RRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
Sbjct: 267 RRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 314


>gi|117938734 constitutive androstane receptor isoform 5 [Homo
           sapiens]
          Length = 309

 Score =  607 bits (1566), Expect = e-174
 Identities = 309/348 (88%), Positives = 309/348 (88%), Gaps = 39/348 (11%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLE 240
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR         
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR--------- 231

Query: 241 LLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQ 300
                                         DRPGVTQRDEIDQLQEEMALTLQSYIKGQQ
Sbjct: 232 ------------------------------DRPGVTQRDEIDQLQEEMALTLQSYIKGQQ 261

Query: 301 RRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 348
           RRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
Sbjct: 262 RRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS 309


>gi|117938748 constitutive androstane receptor isoform 14 [Homo
           sapiens]
          Length = 306

 Score =  545 bits (1405), Expect = e-155
 Identities = 271/271 (100%), Positives = 271/271 (100%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGV 275
           NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGV
Sbjct: 187 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGV 246

Query: 276 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 306
           TQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 247 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 277


>gi|117938744 constitutive androstane receptor isoform 13 [Homo
           sapiens]
          Length = 311

 Score =  539 bits (1389), Expect = e-153
 Identities = 271/276 (98%), Positives = 271/276 (98%), Gaps = 5/276 (1%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP----- 270
           NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP     
Sbjct: 187 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPAPYLT 246

Query: 271 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 306
           DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 247 DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 282


>gi|117938738 constitutive androstane receptor isoform 12 [Homo
           sapiens]
          Length = 315

 Score =  533 bits (1374), Expect = e-152
 Identities = 271/280 (96%), Positives = 271/280 (96%), Gaps = 9/280 (3%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGAR----VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP- 270
           NFLCGPLRYTIEDGAR    VGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSP 
Sbjct: 187 NFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPA 246

Query: 271 ----DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 306
               DRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 247 PYLTDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 286


>gi|117938732 constitutive androstane receptor isoform 11 [Homo
           sapiens]
          Length = 280

 Score =  531 bits (1367), Expect = e-151
 Identities = 274/313 (87%), Positives = 274/313 (87%), Gaps = 39/313 (12%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGV 275
           NFLCGPLRYTIEDGAR                                       DRPGV
Sbjct: 187 NFLCGPLRYTIEDGAR---------------------------------------DRPGV 207

Query: 276 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQG 335
           TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQG
Sbjct: 208 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQG 267

Query: 336 LSAMMPLLQEICS 348
           LSAMMPLLQEICS
Sbjct: 268 LSAMMPLLQEICS 280


>gi|117938740 constitutive androstane receptor isoform 8 [Homo
           sapiens]
          Length = 296

 Score =  526 bits (1356), Expect = e-150
 Identities = 267/306 (87%), Positives = 267/306 (87%), Gaps = 39/306 (12%)

Query: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60
           MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR
Sbjct: 1   MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQR 60

Query: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120
           RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA
Sbjct: 61  RHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGA 120

Query: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180
           HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP
Sbjct: 121 HTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLP 180

Query: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLE 240
           VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR         
Sbjct: 181 VFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGAR--------- 231

Query: 241 LLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQ 300
                                         DRPGVTQRDEIDQLQEEMALTLQSYIKGQQ
Sbjct: 232 ------------------------------DRPGVTQRDEIDQLQEEMALTLQSYIKGQQ 261

Query: 301 RRPRDR 306
           RRPRDR
Sbjct: 262 RRPRDR 267


>gi|117938742 constitutive androstane receptor isoform 15 [Homo
           sapiens]
          Length = 267

 Score =  450 bits (1157), Expect = e-126
 Identities = 232/271 (85%), Positives = 232/271 (85%), Gaps = 39/271 (14%)

Query: 36  RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 95
           RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA
Sbjct: 7   RRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQA 66

Query: 96  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 155
           QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL
Sbjct: 67  QRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVL 126

Query: 156 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 215
           PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ
Sbjct: 127 PLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQ 186

Query: 216 NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGV 275
           NFLCGPLRYTIEDGAR                                       DRPGV
Sbjct: 187 NFLCGPLRYTIEDGAR---------------------------------------DRPGV 207

Query: 276 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 306
           TQRDEIDQLQEEMALTLQSYIKGQQRRPRDR
Sbjct: 208 TQRDEIDQLQEEMALTLQSYIKGQQRRPRDR 238


>gi|14702164 nuclear receptor subfamily 1, group I, member 2 isoform
           3 [Homo sapiens]
          Length = 397

 Score =  299 bits (765), Expect = 3e-81
 Identities = 161/352 (45%), Positives = 223/352 (63%), Gaps = 17/352 (4%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQ 69
           C VCGD+ATGYHFN +TCEGCKGFFRR + ++    CPF  G+CE+++  RR C ACRL+
Sbjct: 41  CRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLR 100

Query: 70  KCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQ------LSKEQEELIRTLLGAHTR 123
           KCL++GM+K+MI+S EA+  RRA   ++++++T  Q      L++EQ  +IR L+ A  +
Sbjct: 101 KCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMK 160

Query: 124 HMGTMFEQFVQFRPPAHLFIHHQPLPTLAP--------VLPLVTHFADINTFMVLQVIKF 175
              T F  F  FR    L      +    P        +  L+ H AD++T+M   +I F
Sbjct: 161 TFDTTFSHFKNFRVSLQLRGEDGSVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISF 220

Query: 176 TKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQ 235
            K +  FR LPIEDQISLLKGAA E+C +  NT F  +T  + CG L Y +ED A  GFQ
Sbjct: 221 AKVISYFRDLPIEDQISLLKGAAFELCQLRFNTVFNAETGTWECGRLSYCLEDTAG-GFQ 279

Query: 236 VEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSY 295
              LE +  FH  L+KLQL E EYVL+ A++LFSPDRPGV Q   +DQLQE+ A+TL+SY
Sbjct: 280 QLLLEPMLKFHYMLKKLQLHEEEYVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSY 339

Query: 296 IKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAM-MPLLQEI 346
           I+  + +P  RFL+ K++ +L ELRSIN  +  ++  IQ +     PL+QE+
Sbjct: 340 IECNRPQPAHRFLFLKIMAMLTELRSINAQHTQRLLRIQDIHPFATPLMQEL 391


>gi|11863132 nuclear receptor subfamily 1, group I, member 2 isoform
           2 [Homo sapiens]
          Length = 473

 Score =  287 bits (735), Expect = 9e-78
 Identities = 164/389 (42%), Positives = 226/389 (58%), Gaps = 54/389 (13%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQ 69
           C VCGD+ATGYHFN +TCEGCKGFFRR + ++    CPF  G+CE+++  RR C ACRL+
Sbjct: 80  CRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLR 139

Query: 70  KCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQ------LSKEQEELIRTLLGAHTR 123
           KCL++GM+K+MI+S EA+  RRA   ++++++T  Q      L++EQ  +IR L+ A  +
Sbjct: 140 KCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMK 199

Query: 124 HMGTMFEQFVQFRPPAHLFIHHQ-PLPTLAP----------------------------- 153
              T F  F  FR P  L    + P    AP                             
Sbjct: 200 TFDTTFSHFKNFRLPGVLSSGCELPESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDG 259

Query: 154 ---------------VLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAA 198
                          +  L+ H AD++T+M   +I F K +  FR LPIEDQISLLKGAA
Sbjct: 260 SVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAA 319

Query: 199 VEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPE 258
            E+C +  NT F  +T  + CG L Y +ED A  GFQ   LE +  FH  L+KLQL E E
Sbjct: 320 FELCQLRFNTVFNAETGTWECGRLSYCLEDTAG-GFQQLLLEPMLKFHYMLKKLQLHEEE 378

Query: 259 YVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAE 318
           YVL+ A++LFSPDRPGV Q   +DQLQE+ A+TL+SYI+  + +P  RFL+ K++ +L E
Sbjct: 379 YVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTE 438

Query: 319 LRSINEAYGYQIQHIQGLSAM-MPLLQEI 346
           LRSIN  +  ++  IQ +     PL+QE+
Sbjct: 439 LRSINAQHTQRLLRIQDIHPFATPLMQEL 467


>gi|34398348 nuclear receptor subfamily 1, group I, member 2 isoform
           1 [Homo sapiens]
          Length = 434

 Score =  287 bits (735), Expect = 9e-78
 Identities = 164/389 (42%), Positives = 226/389 (58%), Gaps = 54/389 (13%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFA-GSCEVSKTQRRHCPACRLQ 69
           C VCGD+ATGYHFN +TCEGCKGFFRR + ++    CPF  G+CE+++  RR C ACRL+
Sbjct: 41  CRVCGDKATGYHFNVMTCEGCKGFFRRAMKRNARLRCPFRKGACEITRKTRRQCQACRLR 100

Query: 70  KCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQ------LSKEQEELIRTLLGAHTR 123
           KCL++GM+K+MI+S EA+  RRA   ++++++T  Q      L++EQ  +IR L+ A  +
Sbjct: 101 KCLESGMKKEMIMSDEAVEERRALIKRKKSERTGTQPLGVQGLTEEQRMMIRELMDAQMK 160

Query: 124 HMGTMFEQFVQFRPPAHLFIHHQ-PLPTLAP----------------------------- 153
              T F  F  FR P  L    + P    AP                             
Sbjct: 161 TFDTTFSHFKNFRLPGVLSSGCELPESLQAPSREEAAKWSQVRKDLCSLKVSLQLRGEDG 220

Query: 154 ---------------VLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAA 198
                          +  L+ H AD++T+M   +I F K +  FR LPIEDQISLLKGAA
Sbjct: 221 SVWNYKPPADSGGKEIFSLLPHMADMSTYMFKGIISFAKVISYFRDLPIEDQISLLKGAA 280

Query: 199 VEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPE 258
            E+C +  NT F  +T  + CG L Y +ED A  GFQ   LE +  FH  L+KLQL E E
Sbjct: 281 FELCQLRFNTVFNAETGTWECGRLSYCLEDTAG-GFQQLLLEPMLKFHYMLKKLQLHEEE 339

Query: 259 YVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAE 318
           YVL+ A++LFSPDRPGV Q   +DQLQE+ A+TL+SYI+  + +P  RFL+ K++ +L E
Sbjct: 340 YVLMQAISLFSPDRPGVLQHRVVDQLQEQFAITLKSYIECNRPQPAHRFLFLKIMAMLTE 399

Query: 319 LRSINEAYGYQIQHIQGLSAM-MPLLQEI 346
           LRSIN  +  ++  IQ +     PL+QE+
Sbjct: 400 LRSINAQHTQRLLRIQDIHPFATPLMQEL 428


>gi|194294519 nuclear receptor subfamily 1, group H, member 3
           isoform c [Homo sapiens]
          Length = 402

 Score =  188 bits (477), Expect = 7e-48
 Identities = 116/352 (32%), Positives = 182/352 (51%), Gaps = 23/352 (6%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
           C VCGD+A+G+H+N L+CEGCKGFFRR+V K     C   G C +    RR C  CRL+K
Sbjct: 53  CSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRK 112

Query: 71  CLDAGMRKDMILSAEALALRRAKQAQR----------RAQQTP---VQLSKEQEELIRTL 117
           C  AGMR++ +LS E + L++ K+ +           RA   P    QLS EQ  +I  L
Sbjct: 113 CRQAGMREECVLSEEQIRLKKLKRQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKL 172

Query: 118 LGAHTRHMGTMFEQFVQFRP-PAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFT 176
           + A  +     F   ++  P P     H +             HF ++    V +++ F 
Sbjct: 173 VAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQ-----QRFAHFTELAIVSVQEIVDFA 227

Query: 177 KDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVGFQ 235
           K LP F  L  EDQI+LLK +A+E+  +  +  +   +++        Y  ED A+ G Q
Sbjct: 228 KQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQ 287

Query: 236 VEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSY 295
           VEF+  +F F   + +LQL + E+ LL A+++FS DRP V  + ++++LQ      L +Y
Sbjct: 288 VEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAY 347

Query: 296 IKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMM-PLLQEI 346
           +      P DR ++ ++L  L  LR+++  +  Q+  ++     + PLL EI
Sbjct: 348 V--SIHHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEI 397


>gi|194294517 nuclear receptor subfamily 1, group H, member 3
           isoform a [Homo sapiens]
          Length = 447

 Score =  188 bits (477), Expect = 7e-48
 Identities = 116/352 (32%), Positives = 182/352 (51%), Gaps = 23/352 (6%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
           C VCGD+A+G+H+N L+CEGCKGFFRR+V K     C   G C +    RR C  CRL+K
Sbjct: 98  CSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRK 157

Query: 71  CLDAGMRKDMILSAEALALRRAKQAQR----------RAQQTP---VQLSKEQEELIRTL 117
           C  AGMR++ +LS E + L++ K+ +           RA   P    QLS EQ  +I  L
Sbjct: 158 CRQAGMREECVLSEEQIRLKKLKRQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKL 217

Query: 118 LGAHTRHMGTMFEQFVQFRP-PAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFT 176
           + A  +     F   ++  P P     H +             HF ++    V +++ F 
Sbjct: 218 VAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQ-----QRFAHFTELAIVSVQEIVDFA 272

Query: 177 KDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRYTIEDGARVGFQ 235
           K LP F  L  EDQI+LLK +A+E+  +  +  +   +++        Y  ED A+ G Q
Sbjct: 273 KQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQ 332

Query: 236 VEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSY 295
           VEF+  +F F   + +LQL + E+ LL A+++FS DRP V  + ++++LQ      L +Y
Sbjct: 333 VEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAY 392

Query: 296 IKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMM-PLLQEI 346
           +      P DR ++ ++L  L  LR+++  +  Q+  ++     + PLL EI
Sbjct: 393 V--SIHHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEI 442


>gi|85362735 nuclear receptor subfamily 1, group H, member 2 [Homo
           sapiens]
          Length = 461

 Score =  170 bits (430), Expect = 2e-42
 Identities = 115/383 (30%), Positives = 184/383 (48%), Gaps = 60/383 (15%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGP--TCPFAGSCEVSKTQRRHCPACRL 68
           C VCGD+A+G+H+N L+CEGCKGFFRR+V +       C   G+C++    RR C  CRL
Sbjct: 87  CRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRL 146

Query: 69  QKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTP------------------------- 103
           +KC +AGMR+  +LS E +  ++ ++ Q++  Q+                          
Sbjct: 147 RKCKEAGMREQCVLSEEQIRKKKIRKQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSE 206

Query: 104 -----------VQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRP------PAHLFIHHQ 146
                      VQL+  QE +I+ L+ A  +     F    +  P      P       Q
Sbjct: 207 AGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQ 266

Query: 147 PLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVL 206
                        HF ++    V +++ F K +P F  L  EDQI+LLK + +EI  +  
Sbjct: 267 RF----------AHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLET 316

Query: 207 NTTFCLQTQ--NFLCGPLRYTIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAA 264
              +  +T+   FL     Y+ +D  R G QVEF+  +F F   +R+L L + EY LL A
Sbjct: 317 ARRYNHETECITFL-KDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIA 375

Query: 265 MALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINE 324
           + +FS DRP V +   ++ LQ+     L SY +   +RP+D+  + ++L  L  LR+++ 
Sbjct: 376 INIFSADRPNVQEPGRVEALQQPYVEALLSYTR--IKRPQDQLRFPRMLMKLVSLRTLSS 433

Query: 325 AYGYQIQHIQGLSAMM-PLLQEI 346
            +  Q+  ++     + PLL EI
Sbjct: 434 VHSEQVFALRLQDKKLPPLLSEI 456


>gi|189491771 thyroid hormone receptor, beta [Homo sapiens]
          Length = 461

 Score =  169 bits (429), Expect = 3e-42
 Identities = 116/350 (33%), Positives = 174/350 (49%), Gaps = 29/350 (8%)

Query: 5   EDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGP--TCPFAGSCEVSKTQRRH 62
           +DEL  CVVCGD+ATGYH+  +TCEGCKGFFRRT+ K++ P  +C + G C + K  R  
Sbjct: 103 KDEL--CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQ 160

Query: 63  CPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSK----------EQEE 112
           C  CR +KC+  GM  D++L       +R    + R ++   +L K          E+ E
Sbjct: 161 CQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWE 220

Query: 113 LIRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPV-----LPLVTHFADIN 165
           LI+T+  AH  T   G+ ++Q  +F P     I   P+   AP      L   +HF  I 
Sbjct: 221 LIKTVTEAHVATNAQGSHWKQKRKFLPED---IGQAPIVN-APEGGKVDLEAFSHFTKII 276

Query: 166 TFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRY 224
           T  + +V+ F K LP+F  LP EDQI LLKG  +EI  +     +  +++   L G +  
Sbjct: 277 TPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAV 336

Query: 225 TIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQL 284
           T       G  V   + +F    +L    L + E  LL A+ L S DRPG+   + I++ 
Sbjct: 337 TRGQLKNGGLGV-VSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKY 395

Query: 285 QEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQ 334
           Q+   L  + YI    R+      + KLL  + +LR I   +  +  H++
Sbjct: 396 QDSFLLAFEHYI--NYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLHMK 443


>gi|189491769 thyroid hormone receptor, beta [Homo sapiens]
          Length = 461

 Score =  169 bits (429), Expect = 3e-42
 Identities = 116/350 (33%), Positives = 174/350 (49%), Gaps = 29/350 (8%)

Query: 5   EDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGP--TCPFAGSCEVSKTQRRH 62
           +DEL  CVVCGD+ATGYH+  +TCEGCKGFFRRT+ K++ P  +C + G C + K  R  
Sbjct: 103 KDEL--CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQ 160

Query: 63  CPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSK----------EQEE 112
           C  CR +KC+  GM  D++L       +R    + R ++   +L K          E+ E
Sbjct: 161 CQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWE 220

Query: 113 LIRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPV-----LPLVTHFADIN 165
           LI+T+  AH  T   G+ ++Q  +F P     I   P+   AP      L   +HF  I 
Sbjct: 221 LIKTVTEAHVATNAQGSHWKQKRKFLPED---IGQAPIVN-APEGGKVDLEAFSHFTKII 276

Query: 166 TFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRY 224
           T  + +V+ F K LP+F  LP EDQI LLKG  +EI  +     +  +++   L G +  
Sbjct: 277 TPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAV 336

Query: 225 TIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQL 284
           T       G  V   + +F    +L    L + E  LL A+ L S DRPG+   + I++ 
Sbjct: 337 TRGQLKNGGLGV-VSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKY 395

Query: 285 QEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQ 334
           Q+   L  + YI    R+      + KLL  + +LR I   +  +  H++
Sbjct: 396 QDSFLLAFEHYI--NYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLHMK 443


>gi|40806162 thyroid hormone receptor, beta [Homo sapiens]
          Length = 461

 Score =  169 bits (429), Expect = 3e-42
 Identities = 116/350 (33%), Positives = 174/350 (49%), Gaps = 29/350 (8%)

Query: 5   EDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGP--TCPFAGSCEVSKTQRRH 62
           +DEL  CVVCGD+ATGYH+  +TCEGCKGFFRRT+ K++ P  +C + G C + K  R  
Sbjct: 103 KDEL--CVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQ 160

Query: 63  CPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSK----------EQEE 112
           C  CR +KC+  GM  D++L       +R    + R ++   +L K          E+ E
Sbjct: 161 CQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWE 220

Query: 113 LIRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPV-----LPLVTHFADIN 165
           LI+T+  AH  T   G+ ++Q  +F P     I   P+   AP      L   +HF  I 
Sbjct: 221 LIKTVTEAHVATNAQGSHWKQKRKFLPED---IGQAPIVN-APEGGKVDLEAFSHFTKII 276

Query: 166 TFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRY 224
           T  + +V+ F K LP+F  LP EDQI LLKG  +EI  +     +  +++   L G +  
Sbjct: 277 TPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAV 336

Query: 225 TIEDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQL 284
           T       G  V   + +F    +L    L + E  LL A+ L S DRPG+   + I++ 
Sbjct: 337 TRGQLKNGGLGV-VSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKY 395

Query: 285 QEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQ 334
           Q+   L  + YI    R+      + KLL  + +LR I   +  +  H++
Sbjct: 396 QDSFLLAFEHYI--NYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLHMK 443


>gi|4826980 nuclear receptor subfamily 1, group H, member 4 [Homo
           sapiens]
          Length = 472

 Score =  162 bits (410), Expect = 4e-40
 Identities = 110/331 (33%), Positives = 174/331 (52%), Gaps = 23/331 (6%)

Query: 6   DELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPA 65
           DEL  CVVCGD+A+GYH+NALTCEGCKGFFRR+++K+    C   G+C +    RR C  
Sbjct: 124 DEL--CVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCVMDMYMRRKCQE 181

Query: 66  CRLQKCLDAGMRKDMILS-AEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRH 124
           CRL+KC + GM  + +L+  +  + R  K  ++ A QT   ++++ E      + + T+ 
Sbjct: 182 CRLRKCKEMGMLAECLLTEIQCKSKRLRKNVKQHADQT---VNEDSEGRDLRQVTSTTKS 238

Query: 125 MGTMFEQFVQFRPPAHLFI---HHQPLPTLAPVLPLVTHFADINTFMVLQ---------V 172
                E     +   H  +   + Q +P       L   F+    F++L          +
Sbjct: 239 CREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEMATNHVQVL 298

Query: 173 IKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARV 232
           ++FTK LP F++L  EDQI+LLKG+AVE   +     F  +  +     L   I +    
Sbjct: 299 VEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEERIRNS--- 355

Query: 233 GFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTL 292
           G   E++  +F F+ ++ +L++ + EY LL A+ + SPDR  +  R+ +++LQE +   L
Sbjct: 356 GISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEPLLDVL 415

Query: 293 QSYIKGQQRRPRDRFLYAKLLGLLAELRSIN 323
           Q   K  Q  P +   +A LLG L ELR+ N
Sbjct: 416 QKLCKIHQ--PENPQHFACLLGRLTELRTFN 444


>gi|40806160 thyroid hormone receptor, alpha isoform 1 [Homo
           sapiens]
          Length = 410

 Score =  162 bits (410), Expect = 4e-40
 Identities = 111/348 (31%), Positives = 167/348 (47%), Gaps = 25/348 (7%)

Query: 6   DELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPT--CPFAGSCEVSKTQRRHC 63
           D+   CVVCGD+ATGYH+  +TCEGCKGFFRRT+ K++ PT  C +   C + K  R  C
Sbjct: 48  DKDEQCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQC 107

Query: 64  PACRLQKCLDAGMRKDMILS----------AEALALRRAKQAQRRAQQTPVQLSKEQEEL 113
             CR +KC+  GM  D++L            E    RR K+   R+ Q   + + E+ +L
Sbjct: 108 QLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDL 167

Query: 114 IRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAP----VLPLVTHFADINTF 167
           I     AH  T   G+ ++Q  +F P     I   P+ ++       L   + F  I T 
Sbjct: 168 IHIATEAHRSTNAQGSHWKQRRKFLPDD---IGQSPIVSMPDGDKVDLEAFSEFTKIITP 224

Query: 168 MVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRYTI 226
            + +V+ F K LP+F  LP EDQI LLKG  +EI  +     +  ++    L G +    
Sbjct: 225 AITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKR 284

Query: 227 EDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQE 286
           E     G  V   + +F    +L    L + E  LL A+ L S DR G+   D+I++ QE
Sbjct: 285 EQLKNGGLGV-VSDAIFELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQE 343

Query: 287 EMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQ 334
              L  + Y+    R+      + KLL  + +LR I   +  +  H++
Sbjct: 344 AYLLAFEHYV--NHRKHNIPHFWPKLLMKVTDLRMIGACHASRFLHMK 389


>gi|20127452 thyroid hormone receptor, alpha isoform 2 [Homo
           sapiens]
          Length = 490

 Score =  156 bits (394), Expect = 3e-38
 Identities = 109/335 (32%), Positives = 161/335 (48%), Gaps = 25/335 (7%)

Query: 6   DELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPT--CPFAGSCEVSKTQRRHC 63
           D+   CVVCGD+ATGYH+  +TCEGCKGFFRRT+ K++ PT  C +   C + K  R  C
Sbjct: 48  DKDEQCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQC 107

Query: 64  PACRLQKCLDAGMRKDMILS----------AEALALRRAKQAQRRAQQTPVQLSKEQEEL 113
             CR +KC+  GM  D++L            E    RR K+   R+ Q   + + E+ +L
Sbjct: 108 QLCRFKKCIAVGMAMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDL 167

Query: 114 IRTLLGAH--TRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAP----VLPLVTHFADINTF 167
           I     AH  T   G+ ++Q  +F P     I   P+ ++       L   + F  I T 
Sbjct: 168 IHIATEAHRSTNAQGSHWKQRRKFLPDD---IGQSPIVSMPDGDKVDLEAFSEFTKIITP 224

Query: 168 MVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNF-LCGPLRYTI 226
            + +V+ F K LP+F  LP EDQI LLKG  +EI  +     +  ++    L G +    
Sbjct: 225 AITRVVDFAKKLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKR 284

Query: 227 EDGARVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQE 286
           E     G  V   + +F    +L    L + E  LL A+ L S DR G+   D+I++ QE
Sbjct: 285 EQLKNGGLGV-VSDAIFELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQE 343

Query: 287 EMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRS 321
              L  + Y+    R+      + KLL    E++S
Sbjct: 344 AYLLAFEHYV--NHRKHNIPHFWPKLLMKEREVQS 376


>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
          Length = 462

 Score =  151 bits (382), Expect = 7e-37
 Identities = 105/343 (30%), Positives = 173/343 (50%), Gaps = 24/343 (6%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
           C VC D+++GYH+    CEGCKGFFRR++ K++  TC    +C ++K  R  C  CRLQK
Sbjct: 88  CFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQK 147

Query: 71  CLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFE 130
           C + GM K+ + +      ++ K+  +        L+ E  ELI  +  AH        E
Sbjct: 148 CFEVGMSKESVRNDRN---KKKKEVPKPECSESYTLTPEVGELIEKVRKAHQ-------E 197

Query: 131 QFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQ 190
            F           ++     ++  + L   F++++T  +++ ++F K LP F +L I DQ
Sbjct: 198 TFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQ 257

Query: 191 ISLLKGAAVEICHIVLNTTFCLQ--TQNFLCG-PLRYTIEDGARVGFQVEFLELLFHFHG 247
           I+LLK A ++I  + + T +  +  T  F  G  L  T    A  G      +L+F F  
Sbjct: 258 ITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFG---PLTDLVFAFAN 314

Query: 248 TLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRF 307
            L  L++ + E  LL+A+ L   DR  + Q D +D LQE +   L+ Y++  +RRP    
Sbjct: 315 QLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVR--KRRPSRPH 372

Query: 308 LYAKLLGLLAELRSINEAYGYQI----QHIQGLSAMMPLLQEI 346
           ++ K+L  + +LRSI+     ++      I G  +M PL+QE+
Sbjct: 373 MFPKMLMKITDLRSISAKGAERVITLKMEIPG--SMPPLIQEM 413


>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
          Length = 457

 Score =  151 bits (382), Expect = 7e-37
 Identities = 105/343 (30%), Positives = 173/343 (50%), Gaps = 24/343 (6%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
           C VC D+++GYH+    CEGCKGFFRR++ K++  TC    +C ++K  R  C  CRLQK
Sbjct: 83  CFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQK 142

Query: 71  CLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFE 130
           C + GM K+ + +      ++ K+  +        L+ E  ELI  +  AH        E
Sbjct: 143 CFEVGMSKESVRNDRN---KKKKEVPKPECSESYTLTPEVGELIEKVRKAHQ-------E 192

Query: 131 QFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQ 190
            F           ++     ++  + L   F++++T  +++ ++F K LP F +L I DQ
Sbjct: 193 TFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQ 252

Query: 191 ISLLKGAAVEICHIVLNTTFCLQ--TQNFLCG-PLRYTIEDGARVGFQVEFLELLFHFHG 247
           I+LLK A ++I  + + T +  +  T  F  G  L  T    A  G      +L+F F  
Sbjct: 253 ITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFG---PLTDLVFAFAN 309

Query: 248 TLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRF 307
            L  L++ + E  LL+A+ L   DR  + Q D +D LQE +   L+ Y++  +RRP    
Sbjct: 310 QLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVR--KRRPSRPH 367

Query: 308 LYAKLLGLLAELRSINEAYGYQI----QHIQGLSAMMPLLQEI 346
           ++ K+L  + +LRSI+     ++      I G  +M PL+QE+
Sbjct: 368 MFPKMLMKITDLRSISAKGAERVITLKMEIPG--SMPPLIQEM 408


>gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
          Length = 462

 Score =  151 bits (382), Expect = 7e-37
 Identities = 105/343 (30%), Positives = 173/343 (50%), Gaps = 24/343 (6%)

Query: 11  CVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQK 70
           C VC D+++GYH+    CEGCKGFFRR++ K++  TC    +C ++K  R  C  CRLQK
Sbjct: 88  CFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQK 147

Query: 71  CLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFE 130
           C + GM K+ + +      ++ K+  +        L+ E  ELI  +  AH        E
Sbjct: 148 CFEVGMSKESVRNDRN---KKKKEVPKPECSESYTLTPEVGELIEKVRKAHQ-------E 197

Query: 131 QFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQ 190
            F           ++     ++  + L   F++++T  +++ ++F K LP F +L I DQ
Sbjct: 198 TFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQ 257

Query: 191 ISLLKGAAVEICHIVLNTTFCLQ--TQNFLCG-PLRYTIEDGARVGFQVEFLELLFHFHG 247
           I+LLK A ++I  + + T +  +  T  F  G  L  T    A  G      +L+F F  
Sbjct: 258 ITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFG---PLTDLVFAFAN 314

Query: 248 TLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRF 307
            L  L++ + E  LL+A+ L   DR  + Q D +D LQE +   L+ Y++  +RRP    
Sbjct: 315 QLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVR--KRRPSRPH 372

Query: 308 LYAKLLGLLAELRSINEAYGYQI----QHIQGLSAMMPLLQEI 346
           ++ K+L  + +LRSI+     ++      I G  +M PL+QE+
Sbjct: 373 MFPKMLMKITDLRSISAKGAERVITLKMEIPG--SMPPLIQEM 413


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.139    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,728,382
Number of Sequences: 37866
Number of extensions: 544188
Number of successful extensions: 2322
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 120
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 1978
Number of HSP's gapped (non-prelim): 204
length of query: 348
length of database: 18,247,518
effective HSP length: 103
effective length of query: 245
effective length of database: 14,347,320
effective search space: 3515093400
effective search space used: 3515093400
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.