BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|47933389 solute carrier family 2, member 9 protein isoform 2 [Homo sapiens] (511 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|47933389 solute carrier family 2, member 9 protein isoform 2 ... 1012 0.0 gi|47933387 solute carrier family 2, member 9 protein isoform 1 ... 974 0.0 gi|4507013 solute carrier family 2 (facilitated glucose/fructose... 439 e-123 gi|134053883 intestinal facilitative glucose transporter 7 [Homo... 431 e-121 gi|190684655 glucose transporter protein 10 isoform a [Homo sapi... 390 e-108 gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens] 389 e-108 gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens] 389 e-108 gi|166795299 solute carrier family 2 (facilitated glucose transp... 365 e-101 gi|4507011 glucose transporter 4 [Homo sapiens] 339 4e-93 gi|5902090 solute carrier family 2 (facilitated glucose transpor... 323 2e-88 gi|23592238 glucose transporter 14 [Homo sapiens] 323 3e-88 gi|4557851 solute carrier family 2 (facilitated glucose transpor... 259 4e-69 gi|207447703 solute carrier family 2 (facilitated glucose/fructo... 168 9e-42 gi|21361449 solute carrier family 2 (facilitated glucose transpo... 136 4e-32 gi|223029432 solute carrier family 2 (facilitated glucose transp... 135 9e-32 gi|223029430 solute carrier family 2 (facilitated glucose transp... 124 2e-28 gi|203098995 solute carrier family 2 (facilitated glucose transp... 115 1e-25 gi|21553331 solute carrier family 2 (facilitated glucose transpo... 89 9e-18 gi|13540547 solute carrier family 2 member 10 [Homo sapiens] 68 2e-11 gi|90669191 solute carrier family 22 member 7 isoform b [Homo sa... 60 6e-09 gi|24497497 solute carrier family 22 member 7 isoform a [Homo sa... 60 6e-09 gi|213021148 SVOP-like isoform 1 [Homo sapiens] 54 3e-07 gi|24497476 solute carrier family 22 member 6 isoform b [Homo sa... 54 4e-07 gi|20070188 solute carrier family 22 member 6 isoform a [Homo sa... 54 4e-07 gi|24497480 solute carrier family 22 member 6 isoform d [Homo sa... 53 8e-07 gi|24497478 solute carrier family 22 member 6 isoform c [Homo sa... 53 8e-07 gi|7662270 synaptic vesicle protein 2B homolog [Homo sapiens] 52 1e-06 gi|33457322 SVOP-like isoform 2 [Homo sapiens] 52 1e-06 gi|11415038 solute carrier family 22 member 3 [Homo sapiens] 52 2e-06 gi|239751156 PREDICTED: hypothetical protein LOC146429 isoform 6... 51 2e-06 >gi|47933389 solute carrier family 2, member 9 protein isoform 2 [Homo sapiens] Length = 511 Score = 1012 bits (2616), Expect = 0.0 Identities = 511/511 (100%), Positives = 511/511 (100%) Query: 1 MKLSKKDRGEDEESDSAKKKLDWSCSLLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFY 60 MKLSKKDRGEDEESDSAKKKLDWSCSLLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFY Sbjct: 1 MKLSKKDRGEDEESDSAKKKLDWSCSLLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFY 60 Query: 61 NESWERRHGRPIDPDTLTLLWSVTVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAI 120 NESWERRHGRPIDPDTLTLLWSVTVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAI Sbjct: 61 NESWERRHGRPIDPDTLTLLWSVTVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAI 120 Query: 121 SAALLMACSLQAGAFEMLIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFI 180 SAALLMACSLQAGAFEMLIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFI Sbjct: 121 SAALLMACSLQAGAFEMLIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFI 180 Query: 181 CIGVFTGQLLGLPELLGKESTWPYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARA 240 CIGVFTGQLLGLPELLGKESTWPYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARA Sbjct: 181 CIGVFTGQLLGLPELLGKESTWPYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARA 240 Query: 241 VKAFQTFLGKADVSQEVEEVLAESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQL 300 VKAFQTFLGKADVSQEVEEVLAESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQL Sbjct: 241 VKAFQTFLGKADVSQEVEEVLAESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQL 300 Query: 301 CGLNAIWFYTNSIFGKAGIPPAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFG 360 CGLNAIWFYTNSIFGKAGIPPAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFG Sbjct: 301 CGLNAIWFYTNSIFGKAGIPPAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFG 360 Query: 361 LMGLFFGTLTITLTLQDHAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPA 420 LMGLFFGTLTITLTLQDHAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPA Sbjct: 361 LMGLFFGTLTITLTLQDHAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPA 420 Query: 421 AFIIAGTVNWLSNFAVGLLFPFIQKSLDTYCFLVFATICITGAIYLYFVLPETKNRTYAE 480 AFIIAGTVNWLSNFAVGLLFPFIQKSLDTYCFLVFATICITGAIYLYFVLPETKNRTYAE Sbjct: 421 AFIIAGTVNWLSNFAVGLLFPFIQKSLDTYCFLVFATICITGAIYLYFVLPETKNRTYAE 480 Query: 481 ISQAFSKRNKAYPPEEKIDSAVTDGKINGRP 511 ISQAFSKRNKAYPPEEKIDSAVTDGKINGRP Sbjct: 481 ISQAFSKRNKAYPPEEKIDSAVTDGKINGRP 511 >gi|47933387 solute carrier family 2, member 9 protein isoform 1 [Homo sapiens] Length = 540 Score = 974 bits (2517), Expect = 0.0 Identities = 490/494 (99%), Positives = 493/494 (99%) Query: 18 KKKLDWSCSLLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTL 77 +++ DWSCSLLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTL Sbjct: 47 RRRKDWSCSLLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTL 106 Query: 78 TLLWSVTVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEM 137 TLLWSVTVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEM Sbjct: 107 TLLWSVTVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEM 166 Query: 138 LIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLG 197 LIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLG Sbjct: 167 LIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLG 226 Query: 198 KESTWPYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEV 257 KESTWPYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEV Sbjct: 227 KESTWPYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEV 286 Query: 258 EEVLAESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKA 317 EEVLAESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKA Sbjct: 287 EEVLAESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKA 346 Query: 318 GIPPAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQD 377 GIPPAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQD Sbjct: 347 GIPPAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQD 406 Query: 378 HAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVG 437 HAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVG Sbjct: 407 HAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVG 466 Query: 438 LLFPFIQKSLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNKAYPPEEK 497 LLFPFIQKSLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNKAYPPEEK Sbjct: 467 LLFPFIQKSLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNKAYPPEEK 526 Query: 498 IDSAVTDGKINGRP 511 IDSAVTDGKINGRP Sbjct: 527 IDSAVTDGKINGRP 540 >gi|4507013 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 isoform 1 [Homo sapiens] Length = 501 Score = 439 bits (1128), Expect = e-123 Identities = 221/490 (45%), Positives = 319/490 (65%), Gaps = 3/490 (0%) Query: 12 EESDSAKKKLDWSCSLLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRP 71 E+ D + K+ + L +A+L AFGSSF YGYN++ VN+P ++ FYNE++ R G Sbjct: 2 EQQDQSMKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEF 61 Query: 72 IDPDTLTLLWSVTVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQ 131 ++ LTLLWSVTVS+F GG +G+L+V + GRK LL NN F+I A+LM CS Sbjct: 62 MEDFPLTLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRV 121 Query: 132 AGAFEMLIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLG 191 A +FE++I+ R ++GI GV+ +V+PMYL E++PK +RG+LG V +FI +G+ Q+ G Sbjct: 122 ATSFELIIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFG 181 Query: 192 LPELLGKESTWPYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKA 251 L LL WP L G+ VPA +QLL LPF P+SPRYLL++K +EA A KA QT G Sbjct: 182 LRNLLANVDGWPILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWD 241 Query: 252 DVSQEVEEVLAESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTN 311 V +EV E+ E +++ +SVL+L R +RWQ++++IV M QL G+NAI++Y + Sbjct: 242 SVDREVAEIRQEDEAEKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYAD 301 Query: 312 SIFGKAGIPPAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTI 371 I+ AG+P + YVT TG + + + V+E LGRR LL+ GF + + LT Sbjct: 302 QIYLSAGVPEEHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTA 361 Query: 372 TLTLQDHAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWL 431 L LQD W+PY+SIV +++ + GP IP +L E F QS RP+AF++ G+V+WL Sbjct: 362 ALALQDTVSWMPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWL 421 Query: 432 SNFAVGLLFPFIQKSLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNK- 490 SNF VGL+FPFIQ+ L Y F+VFA IC+ IY++ ++PETK +T+ EI+Q F+K NK Sbjct: 422 SNFTVGLIFPFIQEGLGPYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIFTKMNKV 481 Query: 491 --AYPPEEKI 498 YP +E++ Sbjct: 482 SEVYPEKEEL 491 >gi|134053883 intestinal facilitative glucose transporter 7 [Homo sapiens] Length = 512 Score = 431 bits (1109), Expect = e-121 Identities = 212/472 (44%), Positives = 316/472 (66%) Query: 26 SLLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTV 85 +LL+A+L+ AFGS+F YGYNLSVVN P K+FYNE++ RH +D + LLWS TV Sbjct: 22 TLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERHATFMDGKLMLLLWSCTV 81 Query: 86 SIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIM 145 S+F +GGL+G+L+V ++ GRK TLL NN FAI A+LM S A AFE+++ R ++ Sbjct: 82 SMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELIVFSRVVL 141 Query: 146 GIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYL 205 G+ G++ S LPMYL E++PK +RG +G +T +F+ +GVF Q+ L +LG + WP L Sbjct: 142 GVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAGWPVL 201 Query: 206 FGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESR 265 + VPA++QLL+LPF P+SPRY L++K +EA A +A + G D+ E+E++ AE+R Sbjct: 202 LALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDMEAELEDMRAEAR 261 Query: 266 VQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIP 325 +R+ +SVL L +RWQ++++IV MA QL G+NAI +Y ++I+ AG+ A Sbjct: 262 AERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSAGVEAAHSQ 321 Query: 326 YVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYL 385 YVT+ +G + + + S +++E LGRR LL+ G+G+ G LT+ L Q+ P + YL Sbjct: 322 YVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQNRVPELSYL 381 Query: 386 SIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQK 445 I+ + A IA GP +P ++ E F QS R AAF++ G V+WL+NF +G LFP IQ+ Sbjct: 382 GIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFLFPSIQE 441 Query: 446 SLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNKAYPPEEK 497 ++ Y F++FA IC+ AIY+Y V+PETK +T+ EI++ F+KRN+ PEEK Sbjct: 442 AIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAKRNRVKLPEEK 493 >gi|190684655 glucose transporter protein 10 isoform a [Homo sapiens] Length = 503 Score = 390 bits (1001), Expect = e-108 Identities = 198/481 (41%), Positives = 297/481 (61%), Gaps = 1/481 (0%) Query: 10 EDEESDSAKKKLDWSCSLLVASLAGA-FGSSFLYGYNLSVVNAPTPYIKAFYNESWERRH 68 EDE S + + +L+ ++ A G +F +GYNLS++NAPT +I+ F NE+W+ R Sbjct: 2 EDELEPSLRPRTQIQGRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQART 61 Query: 69 GRPIDPDTLTLLWSVTVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMAC 128 G P+ + L+WS+ VS++ +GGL G L+ + LGRK +LL NN F +SAA+L Sbjct: 62 GEPLPDHLVLLMWSLIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGF 121 Query: 129 SLQAGAFEMLIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQ 188 S +AG+FEM+++GR ++G++ GV++++ PMYL E +PKE+RG++ +AIF +G+ GQ Sbjct: 122 SRKAGSFEMIMLGRLLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQ 181 Query: 189 LLGLPELLGKESTWPYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFL 248 ++GL ELLG WP L +VP +QL SLP LP+SPRYLL++ + + A + Sbjct: 182 VVGLRELLGGPQAWPLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLR 241 Query: 249 GKADVSQEVEEVLAESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWF 308 G D++ E+EE+ E + R EL + +R QV +++V + +LCG ++++ Sbjct: 242 GSGDLAGELEELEEERAACQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYA 301 Query: 309 YTNSIFGKAGIPPAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGT 368 Y +S+F KAG+P AKI Y + TG E L AV S +VIE +GRR LLIGG+ LM + Sbjct: 302 YASSVFRKAGVPEAKIQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSI 361 Query: 369 LTITLTLQDHAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTV 428 T+ L LQ PW YL++ I A I SF GP G+ IL E F Q RPAA ++ G + Sbjct: 362 FTVALCLQSSFPWTLYLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGAL 421 Query: 429 NWLSNFAVGLLFPFIQKSLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKR 488 W+ VGL FPFI ++L + ++ F +C+ GAIY LPETK +T+ EIS+ + Sbjct: 422 MWIMLILVGLGFPFIMEALSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRL 481 Query: 489 N 489 N Sbjct: 482 N 482 >gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens] Length = 496 Score = 389 bits (1000), Expect = e-108 Identities = 195/463 (42%), Positives = 289/463 (62%) Query: 27 LLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVS 86 LL+ A G +F +GYNLS++NAPT +I+ F NE+W+ R G P+ + L+WS+ VS Sbjct: 13 LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVS 72 Query: 87 IFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMG 146 ++ +GGL G L+ + LGRK +LL NN F +SAA+L S +AG+FEM+++GR ++G Sbjct: 73 LYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG 132 Query: 147 IDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLF 206 ++ GV++++ PMYL E +PKE+RG++ +AIF +G+ GQ++GL ELLG WP L Sbjct: 133 VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLL 192 Query: 207 GVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRV 266 +VP +QL SLP LP+SPRYLL++ + + A + G D++ E+EE+ E Sbjct: 193 ASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAA 252 Query: 267 QRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPY 326 + R EL + +R QV +++V + +LCG ++++ Y +S+F KAG+P AKI Y Sbjct: 253 CQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQY 312 Query: 327 VTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLS 386 + TG E L AV S +VIE +GRR LLIGG+ LM + T+ L LQ PW YL+ Sbjct: 313 AIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYLA 372 Query: 387 IVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKS 446 + I A I SF GP G+ IL E F Q RPAA ++ G + W+ VGL FPFI ++ Sbjct: 373 MACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEA 432 Query: 447 LDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRN 489 L + ++ F +C+ GAIY LPETK +T+ EIS+ + N Sbjct: 433 LSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLN 475 >gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens] Length = 499 Score = 389 bits (1000), Expect = e-108 Identities = 195/463 (42%), Positives = 289/463 (62%) Query: 27 LLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVS 86 LL+ A G +F +GYNLS++NAPT +I+ F NE+W+ R G P+ + L+WS+ VS Sbjct: 16 LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVS 75 Query: 87 IFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMG 146 ++ +GGL G L+ + LGRK +LL NN F +SAA+L S +AG+FEM+++GR ++G Sbjct: 76 LYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG 135 Query: 147 IDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLF 206 ++ GV++++ PMYL E +PKE+RG++ +AIF +G+ GQ++GL ELLG WP L Sbjct: 136 VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLL 195 Query: 207 GVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRV 266 +VP +QL SLP LP+SPRYLL++ + + A + G D++ E+EE+ E Sbjct: 196 ASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAA 255 Query: 267 QRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPY 326 + R EL + +R QV +++V + +LCG ++++ Y +S+F KAG+P AKI Y Sbjct: 256 CQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQY 315 Query: 327 VTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLS 386 + TG E L AV S +VIE +GRR LLIGG+ LM + T+ L LQ PW YL+ Sbjct: 316 AIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYLA 375 Query: 387 IVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKS 446 + I A I SF GP G+ IL E F Q RPAA ++ G + W+ VGL FPFI ++ Sbjct: 376 MACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEA 435 Query: 447 LDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRN 489 L + ++ F +C+ GAIY LPETK +T+ EIS+ + N Sbjct: 436 LSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLN 478 >gi|166795299 solute carrier family 2 (facilitated glucose transporter), member 1 [Homo sapiens] Length = 492 Score = 365 bits (936), Expect = e-101 Identities = 188/484 (38%), Positives = 289/484 (59%), Gaps = 7/484 (1%) Query: 28 LVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVSI 87 L+ ++ GA S +GYN V+NAP I+ FYN++W R+G I P TLT LWS++V+I Sbjct: 12 LMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTLWSLSVAI 71 Query: 88 FAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGI 147 F++GG++G+ V + GR++++L N A +A+LM S +FEMLI+GRFI+G+ Sbjct: 72 FSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGV 131 Query: 148 DGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFG 207 G+ +PMY+ E+SP +RG+LG + + I +G+ Q+ GL ++G + WP L Sbjct: 132 YCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLS 191 Query: 208 VIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQ 267 +I +PA++Q + LPF P+SPR+LL+ ++ E RA + G ADV+ +++E+ ESR Sbjct: 192 IIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMKEESRQM 251 Query: 268 RSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYV 327 + V++LEL R+P R ++ +V QL G+NA+++Y+ SIF KAG+ + Y Sbjct: 252 MREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGV--QQPVYA 309 Query: 328 TLSTGGIETLAAVFSGLVIEHLGRRPL-LIGGFGLMGLFFGTLTITLTLQDHAPWVPYLS 386 T+ +G + T V S V+E GRR L LIG G+ G +TI L L + PW+ YLS Sbjct: 310 TIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAI-LMTIALALLEQLPWMSYLS 368 Query: 387 IVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKS 446 IV I +A F GPG IP+ + E F Q RPAA +AG NW SNF VG+ F ++++ Sbjct: 369 IVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQL 428 Query: 447 LDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNKAY---PPEEKIDSAVT 503 Y F++F + + I+ YF +PETK RT+ EI+ F + + PEE Sbjct: 429 CGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPEELFHPLGA 488 Query: 504 DGKI 507 D ++ Sbjct: 489 DSQV 492 >gi|4507011 glucose transporter 4 [Homo sapiens] Length = 509 Score = 339 bits (869), Expect = 4e-93 Identities = 183/475 (38%), Positives = 283/475 (59%), Gaps = 8/475 (1%) Query: 28 LVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHG----RPIDPDTLTLLWSV 83 LV ++ A S +GYN+ V+NAP I+ YNE+W R G I P TLT LW++ Sbjct: 24 LVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIPPGTLTTLWAL 83 Query: 84 TVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRF 143 +V+IF++GG++ + ++ +I + LGRK +L NN A+ LM + A ++EMLI+GRF Sbjct: 84 SVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRF 143 Query: 144 IMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWP 203 ++G G+ ++PMY+ EI+P +RG+LG + + I IG+ Q+LGL LLG S WP Sbjct: 144 LIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLWP 203 Query: 204 YLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAE 263 L G+ V+PA++QL+ LPF P+SPRYL + ++ E A K+ + G ADVS + E+ E Sbjct: 204 LLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADVSGVLAELKDE 263 Query: 264 SRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAK 323 R R +S+L+LL + R ++ +V QL G+NA+++Y+ SIF AG+ + Sbjct: 264 KRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFETAGV--GQ 321 Query: 324 IPYVTLSTGGIETLAAVFSGLVIEHLGRRPL-LIGGFGLMGLFFGTLTITLTLQDHAPWV 382 Y T+ G + T+ + S L++E GRR L L+G G+ G +T+ L L + P + Sbjct: 322 PAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAI-LMTVALLLLERVPAM 380 Query: 383 PYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPF 442 Y+SIV I +A F GPG IP+ + E F Q RPAA +AG NW SNF +G+ F + Sbjct: 381 SYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFIIGMGFQY 440 Query: 443 IQKSLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNKAYPPEEK 497 + +++ Y FL+FA + + I+ + +PET+ RT+ +IS AF + E K Sbjct: 441 VAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAFHRTPSLLEQEVK 495 >gi|5902090 solute carrier family 2 (facilitated glucose transporter), member 3 [Homo sapiens] Length = 496 Score = 323 bits (829), Expect = 2e-88 Identities = 170/458 (37%), Positives = 262/458 (57%), Gaps = 2/458 (0%) Query: 28 LVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVSI 87 L+ ++ A SF +GYN V+NAP IK F N++ + P LT LWS++V+I Sbjct: 10 LIFAITVATIGSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWSLSVAI 69 Query: 88 FAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGI 147 F++GG++G+ V + GR++++L N A++ M A + EMLI+GR ++G+ Sbjct: 70 FSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGL 129 Query: 148 DGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFG 207 G+ +PMY+ EISP +RG+ G + + I +G+ Q+ GL +LG E WP L G Sbjct: 130 FCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLG 189 Query: 208 VIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQ 267 ++PA++Q +LPF P+SPR+LL+ + E A + Q G DVSQ+++E+ ES Sbjct: 190 FTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARM 249 Query: 268 RSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYV 327 + V+VLEL R R ++ IV QL G+NA+++Y+ IF AG+ + Y Sbjct: 250 SQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGV--QEPIYA 307 Query: 328 TLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLSI 387 T+ G + T+ V S ++E GRR L + G G M +T++L L+D+ + ++ I Sbjct: 308 TIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGMSFVCI 367 Query: 388 VGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKSL 447 IL +A F GPG IP+ + E F Q RPAA +AG NW SNF VGLLFP L Sbjct: 368 GAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYL 427 Query: 448 DTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAF 485 Y F++F IT + +F +PET+ RT+ +I++AF Sbjct: 428 GAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF 465 >gi|23592238 glucose transporter 14 [Homo sapiens] Length = 520 Score = 323 bits (827), Expect = 3e-88 Identities = 171/458 (37%), Positives = 262/458 (57%), Gaps = 2/458 (0%) Query: 28 LVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVSI 87 L+ ++ A SF +GYN V+NAP IK F N++ + P LT LWS++V+I Sbjct: 34 LIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLSVAI 93 Query: 88 FAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGI 147 F++GG++G+ V + GR++++L N A + LM A + EMLI+GR ++G+ Sbjct: 94 FSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGL 153 Query: 148 DGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFG 207 G+ +PMY+ EISP +RG+ G + + I IG+ Q+ GL +LG E WP L G Sbjct: 154 FCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLG 213 Query: 208 VIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQ 267 ++PA++Q +LP P+SPR+LL+ + E A + Q G DVSQ+++E+ ES Sbjct: 214 FTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEMKDESARM 273 Query: 268 RSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYV 327 + V+VLEL R R ++ IV QL G+NA+++Y+ IF AG+ + Y Sbjct: 274 SQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGV--QQPIYA 331 Query: 328 TLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLSI 387 T+S G + T+ + S ++E GRR L + G G M +T++L L++H + ++ I Sbjct: 332 TISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSFVCI 391 Query: 388 VGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKSL 447 IL +A F GPG IP+ + E F Q RPAA +AG NW SNF VGLLFP L Sbjct: 392 GAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYL 451 Query: 448 DTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAF 485 Y F++F IT + +F +PET+ RT+ +I++AF Sbjct: 452 GAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF 489 >gi|4557851 solute carrier family 2 (facilitated glucose transporter), member 2 [Homo sapiens] Length = 524 Score = 259 bits (662), Expect = 4e-69 Identities = 157/513 (30%), Positives = 257/513 (50%), Gaps = 49/513 (9%) Query: 28 LVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRH--GRPIDP----------- 74 LV ++ A SF +GY++ V+NAP I + Y RH G P+D Sbjct: 10 LVFTVITAVLGSFQFGYDIGVINAPQQVIISHY------RHVLGVPLDDRKAINNYVINS 63 Query: 75 ---------------------------DTLTLLWSVTVSIFAIGGLVGTLIVKMIGKVLG 107 +T+LWS++VS FA+GG+ + +G LG Sbjct: 64 TDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDTLG 123 Query: 108 RKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGIDGGVALSVLPMYLSEISPKE 167 R +L N ++ ALLM S + ++I GR I G+ G+ ++PMY+ EI+P Sbjct: 124 RIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTA 183 Query: 168 IRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGVIVVPAVVQLLSLPFLPDSP 227 +RG+LG + I G+ Q++GL +LG W L G+ V A++Q L L F P+SP Sbjct: 184 LRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESP 243 Query: 228 RYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQRSIRLVSVLELLRAPYVRWQ 287 RYL ++ E +A ++ + G DV++++ E+ E S + VS+++L R Sbjct: 244 RYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQP 303 Query: 288 VVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYVTLSTGGIETLAAVFSGLVIE 347 ++ ++ Q G+N I++Y+ SIF AGI +K Y T+ G + + S ++E Sbjct: 304 ILVALMLHVAQQFSGINGIFYYSTSIFQTAGI--SKPVYATIGVGAVNMVFTAVSVFLVE 361 Query: 348 HLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLSIVGILAIIASFCSGPGGIPFI 407 GRR L + G M + +++ L L + W+ Y+S++ I ++ F GPG IP+ Sbjct: 362 KAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWF 421 Query: 408 LTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKSLDTYCFLVFATICITGAIYLY 467 + EFF Q RPAA IA NW NF V L F +I Y F +FA + + ++ + Sbjct: 422 MVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTF 481 Query: 468 FVLPETKNRTYAEISQAFSKRN-KAYPPEEKID 499 F +PETK +++ EI+ F K++ A+ P+ ++ Sbjct: 482 FKVPETKGKSFEEIAAEFQKKSGSAHRPKAAVE 514 >gi|207447703 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 isoform 2 [Homo sapiens] Length = 244 Score = 168 bits (426), Expect = 9e-42 Identities = 85/185 (45%), Positives = 124/185 (67%) Query: 12 EESDSAKKKLDWSCSLLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRP 71 E+ D + K+ + L +A+L AFGSSF YGYN++ VN+P ++ FYNE++ R G Sbjct: 2 EQQDQSMKEGRLTLVLALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEF 61 Query: 72 IDPDTLTLLWSVTVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQ 131 ++ LTLLWSVTVS+F GG +G+L+V + GRK LL NN F+I A+LM CS Sbjct: 62 MEDFPLTLLWSVTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRV 121 Query: 132 AGAFEMLIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLG 191 A +FE++I+ R ++GI GV+ +V+PMYL E++PK +RG+LG V +FI +G+ Q+ G Sbjct: 122 ATSFELIIISRLLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFG 181 Query: 192 LPELL 196 L LL Sbjct: 182 LRNLL 186 >gi|21361449 solute carrier family 2 (facilitated glucose transporter), member 8 [Homo sapiens] Length = 477 Score = 136 bits (343), Expect = 4e-32 Identities = 119/422 (28%), Positives = 189/422 (44%), Gaps = 47/422 (11%) Query: 89 AIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGID 148 A GG++G +V G+ L LL + F A++ A A ML+ GR + G+ Sbjct: 81 AAGGVLGGWLVDRAGRKLS---LLLCSVPFVAGFAVITA----AQDVWMLLGGRLLTGLA 133 Query: 149 GGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGV 208 GVA V P+Y+SEI+ +RG LG + + +G+ L L G W +L + Sbjct: 134 CGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGIL------LAYLAGWVLEWRWLAVL 187 Query: 209 IVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQR 268 VP + LL + F+P++PR+LL + H A+ A + FL ++ E + AE Sbjct: 188 GCVPPSLMLLLMCFMPETPRFLLTQ-HRRQEAMAALR-FLWGSEQGWEDPPIGAEQSFH- 244 Query: 269 SIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYVT 328 L LLR P + + + MA QL G+NA+ FY +IF +A + + V Sbjct: 245 -------LALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVV 297 Query: 329 LSTGGIETLAAVFSGLVIEHLGRRPLLI---------------------GGFGLMGLFFG 367 + G I+ L + L+++ GRR LL+ GG G Sbjct: 298 V--GVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAI 355 Query: 368 TLTITLTLQDHAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGT 427 + ++ D + + +L++ + IA F G G IP++L E F + A I Sbjct: 356 SAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVL 415 Query: 428 VNWLSNFAVGLLFPFIQKSLDTY-CFLVFATICITGAIYLYFVLPETKNRTYAEISQAFS 486 NWL F V F + + L Y F + + CI ++ F +PETK +T +I+ F Sbjct: 416 TNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFE 475 Query: 487 KR 488 R Sbjct: 476 GR 477 >gi|223029432 solute carrier family 2 (facilitated glucose transporter), member 6 isoform 1 [Homo sapiens] Length = 507 Score = 135 bits (340), Expect = 9e-32 Identities = 134/500 (26%), Positives = 218/500 (43%), Gaps = 66/500 (13%) Query: 27 LLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTV- 85 + +A+ A G+ F +GY L + P ++ R +DPD L L S Sbjct: 38 VFLATFAAVLGN-FSFGYALVYTSPVIPALE------------RSLDPD-LHLTKSQASW 83 Query: 86 --SIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRF 143 S+F +G G L ++ +LGRK +++ + A+ +A A A ML++GR Sbjct: 84 FGSVFTLGAAAGGLSAMILNDLLGRKLSIMFS---AVPSAAGYALMAGAHGLWMLLLGRT 140 Query: 144 IMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWP 203 + G GG+ + +P+Y+SEI+P +RG+LG + G + LGL LL W Sbjct: 141 LTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL--LL----PWR 194 Query: 204 YLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLG-KADVSQEVEEVLA 262 +L P ++ +L L F+P+SPR+LL +E A++A G DV E E++ Sbjct: 195 WLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDE-EALRALAWLRGTDVDVHWEFEQI-- 251 Query: 263 ESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGI--P 320 + V+R VS E RAP+V + ++ QL G+ I Y SIF + P Sbjct: 252 QDNVRRQSSRVSWAE-ARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLP 310 Query: 321 PAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTL----- 375 P + G + L+ + + L ++ GR+ LL +M F LT+ L + Sbjct: 311 PKDDAAI---VGAVRLLSVLIAALTMDLAGRKVLLFVSAAIM--FAANLTLGLYIHFGPR 365 Query: 376 -------------------QDHAPWVPYLSIVGILA---IIASFCSGPGGIPFILTGEFF 413 Q A YL++V +LA I + G G I ++L E Sbjct: 366 PLSPNSTAGLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVL 425 Query: 414 QQSQRPAAFIIAGTVNWLSNFAVGLLF-PFIQKSLDTYCFLVFATICITGAIYLYFVLPE 472 R A + +WL+ F + F P + F FA IC+ ++ +PE Sbjct: 426 PLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPE 485 Query: 473 TKNRTYAEISQAFSKRNKAY 492 TK R+ +I F +++ Sbjct: 486 TKGRSLEQIESFFRTGRRSF 505 >gi|223029430 solute carrier family 2 (facilitated glucose transporter), member 6 isoform 2 [Homo sapiens] Length = 445 Score = 124 bits (312), Expect = 2e-28 Identities = 120/473 (25%), Positives = 201/473 (42%), Gaps = 74/473 (15%) Query: 27 LLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTV- 85 + +A+ A G+ F +GY L + P ++ R +DPD L L S Sbjct: 38 VFLATFAAVLGN-FSFGYALVYTSPVIPALE------------RSLDPD-LHLTKSQASW 83 Query: 86 --SIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRF 143 S+F +G G L ++ +LGRK +++ + A+ +A A A ML++GR Sbjct: 84 FGSVFTLGAAAGGLSAMILNDLLGRKLSIMFS---AVPSAAGYALMAGAHGLWMLLLGRT 140 Query: 144 IMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWP 203 + G GG+ + +P+Y+SEI+P +RG+LG + G + LGL LL W Sbjct: 141 LTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMAVFGSLSLYALGL--LL----PWR 194 Query: 204 YLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLG-KADVSQEVEEVLA 262 +L P ++ +L L F+P+SPR+LL +E A++A G DV E E++ Sbjct: 195 WLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDE-EALRALAWLRGTDVDVHWEFEQI-- 251 Query: 263 ESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGI--P 320 + V+R VS E RAP+V + ++ QL G+ I Y SIF + P Sbjct: 252 QDNVRRQSSRVSWAE-ARAPHVCRPITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLP 310 Query: 321 PAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAP 380 P + G + L+ + + L ++ GR+ Sbjct: 311 PKDDAAI---VGAVRLLSVLIAALTMDLAGRK---------------------------- 339 Query: 381 WVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLF 440 +L ++ + G G I ++L E R A + +WL+ F + F Sbjct: 340 ---------VLLFVSGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSF 390 Query: 441 -PFIQKSLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNKAY 492 P + F FA IC+ ++ +PETK R+ +I F +++ Sbjct: 391 LPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFFRTGRRSF 443 >gi|203098995 solute carrier family 2 (facilitated glucose transporter), member 13 [Homo sapiens] Length = 648 Score = 115 bits (287), Expect = 1e-25 Identities = 96/339 (28%), Positives = 159/339 (46%), Gaps = 35/339 (10%) Query: 29 VASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTL--TLLWSVTVS 86 V ++ A G FL+GY+ VV+ +K R + D L LL S TV Sbjct: 83 VVAVFSALGG-FLFGYDTGVVSGAMLLLK------------RQLSLDALWQELLVSSTVG 129 Query: 87 IFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMG 146 A+ L G + + G+ R LLA+ F +A+L A + + E L+ GR ++G Sbjct: 130 AAAVSALAGGALNGVFGR---RAAILLASALFTAGSAVLAAANNK----ETLLAGRLVVG 182 Query: 147 IDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLL-GLPELLGKESTWPYL 205 + G+A +P+Y++E+SP +RG L + +FI G F ++ G L K+ W Y+ Sbjct: 183 LGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDG-WRYM 241 Query: 206 FGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEV---LA 262 G+ VPAV+Q FLP+SPR+ L++K +A + G + +E + + + Sbjct: 242 LGLAAVPAVIQFFGFLFLPESPRW-LIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIE 300 Query: 263 ESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPA 322 E + + +L P R ++ QL G+N I +Y+ +I +G+ Sbjct: 301 EEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDD 360 Query: 323 KIPY----VTLSTGGIETLAAVFSGLVIEHLGRRPLLIG 357 ++ VT T I TL V+ ++E +GRR L G Sbjct: 361 RLAIWLASVTAFTNFIFTLVGVW---LVEKVGRRKLTFG 396 Score = 54.7 bits (130), Expect = 2e-07 Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 1/106 (0%) Query: 384 YLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFI 443 + +++G++ + F G G +P+ + E + R + +NW+ N V L F Sbjct: 507 WTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHT 566 Query: 444 QKSLDTY-CFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKR 488 + L Y F ++A G +++Y LPETK + EI F R Sbjct: 567 AEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLFDNR 612 >gi|21553331 solute carrier family 2 (facilitated glucose transporter), member 12 [Homo sapiens] Length = 617 Score = 89.0 bits (219), Expect = 9e-18 Identities = 73/336 (21%), Positives = 153/336 (45%), Gaps = 24/336 (7%) Query: 38 SSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVSIFAIGGLVGTL 97 S L GY L +++ IK S + + VS IG L+ +L Sbjct: 50 SGLLVGYELGIISGALLQIKTLLALSCHEQE--------------MVVSSLVIGALLASL 95 Query: 98 IVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGIDGGVALSVLP 157 ++ GR+ ++ ++ +L++ SL ++ +LIVGR +G+ ++ Sbjct: 96 TGGVLIDRYGRRTAIILSSCLLGLGSLVLILSL---SYTVLIVGRIAIGVSISLSSIATC 152 Query: 158 MYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGVIVVPAVVQL 217 +Y++EI+P+ RG L + + I IG+ + + W Y+FG+++ V+Q Sbjct: 153 VYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYA-FANVFHGWKYMFGLVIPLGVLQA 211 Query: 218 LSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQRSIRLVSVLE 277 +++ FLP SPR+L++ K E A K +D ++E+ + + + + S + Sbjct: 212 IAMYFLPPSPRFLVM-KGQEGAASKVLGRLRALSDTTEELTVIKSSLKDEYQ---YSFWD 267 Query: 278 LLRA-PYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAK-IPYVTLSTGGIE 335 L R+ +R +++ + + Q+ G I FY +++ G + + G ++ Sbjct: 268 LFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVK 327 Query: 336 TLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTI 371 ++ + + L+++H+G + L G +M T+ I Sbjct: 328 VISTIPATLLVDHVGSKTFLCIGSSVMAASLVTMGI 363 Score = 52.4 bits (124), Expect = 1e-06 Identities = 29/115 (25%), Positives = 56/115 (48%), Gaps = 3/115 (2%) Query: 377 DHAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAV 436 D ++ +LS+ +L +A+F G G +P+++ E F R A + ++NW N + Sbjct: 455 DVPAFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLI 514 Query: 437 GLLFPFIQK--SLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRN 489 L F + L CF ++ + + +++ +PETK + +IS +K N Sbjct: 515 SLTFLTVTDLIGLPWVCF-IYTIMSLASLLFVVMFIPETKGCSLEQISMELAKVN 568 >gi|13540547 solute carrier family 2 member 10 [Homo sapiens] Length = 541 Score = 67.8 bits (164), Expect = 2e-11 Identities = 72/284 (25%), Positives = 120/284 (42%), Gaps = 30/284 (10%) Query: 88 FAIGGLV-GTLIVKMIGKVL----GRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGR 142 F +G L+ G L+ ++G L GRK +L +N ++ +L + AG+ L++GR Sbjct: 49 FLVGSLLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGL---AGSLAWLVLGR 105 Query: 143 FIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTW 202 ++G ++ +Y+SE+ RG L + I +G+ L L G W Sbjct: 106 AVVGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYA-LAGTPWGW 164 Query: 203 PYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLA 262 ++FG PAV+Q LSL FLP +E K G L Sbjct: 165 RHMFGWATAPAVLQSLSLLFLPAGT--------DETATHKDLIPLQGGE------APKLG 210 Query: 263 ESRVQRSIRLVSVLELLRA-PYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGI-P 320 R + S L+L RA +R + + + QL G + Y ++IF G Sbjct: 211 PGRPR-----YSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGFHG 265 Query: 321 PAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGL 364 + ++ G ++ A + + +++ GRR LL+ G LM L Sbjct: 266 GSSAVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALMAL 309 Score = 57.0 bits (136), Expect = 4e-08 Identities = 27/106 (25%), Positives = 57/106 (53%), Gaps = 1/106 (0%) Query: 384 YLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFI 443 + +++ ++ +++F G G + +++ E + R AF + NW +N + L F + Sbjct: 410 WTALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDL 469 Query: 444 QKSLD-TYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKR 488 ++ ++ FL++ + G ++Y +PETK ++ AEI Q F KR Sbjct: 470 IGTIGLSWTFLLYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQKR 515 >gi|90669191 solute carrier family 22 member 7 isoform b [Homo sapiens] Length = 548 Score = 59.7 bits (143), Expect = 6e-09 Identities = 96/415 (23%), Positives = 163/415 (39%), Gaps = 43/415 (10%) Query: 86 SIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIM 145 + F G LVG + + GR+ LL +S +L S + ++ M + R + Sbjct: 149 TFFFAGVLVGAVAFGYLSDRFGRRRLLLVAY---VSTLVLGLASAASVSYVMFAITRTLT 205 Query: 146 GID-GGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPY 204 G G + V+P+ L + E R G +++ F GV LL L L ++ W + Sbjct: 206 GSALAGFTIIVMPLELEWLDV-EHRTVAGVLSSTFWTGGVM---LLALVGYLIRD--WRW 259 Query: 205 LFGVIVVPAVVQLLSLPFLPDSPRYLLLEKH-NEARAVKAFQTFLGKADVSQEVEEVLAE 263 L + +P +LSL ++P+S R+LL + H EA L V ++ A Sbjct: 260 LLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAV 319 Query: 264 SRV---QRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIP 320 S+V +R +R S L+L R P +R +++ C +WF N + + Sbjct: 320 SKVAAGERVVRRPSYLDLFRTPRLRH------ISLCCV------VVWFGVNFSYYGLSLD 367 Query: 321 PA----KIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQ 376 + + L G +E + + L + + GRR G L FGT L Sbjct: 368 VSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTR--LLVSS 425 Query: 377 DHAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAV 436 D W L+++G A+F + ++ T E + R + V L Sbjct: 426 DMKSWSTVLAVMGKAFSEAAFTTA-----YLFTSELYPTVLRQTGMGLTALVGRLGGSLA 480 Query: 437 GL--LFPFIQKSLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRN 489 L L + SL + A + A+ +LPET+ E Q +++ Sbjct: 481 PLAALLDGVWLSLPKLTYGGIALLAAGTAL----LLPETRQAQLPETIQDVERKS 531 >gi|24497497 solute carrier family 22 member 7 isoform a [Homo sapiens] Length = 546 Score = 59.7 bits (143), Expect = 6e-09 Identities = 96/415 (23%), Positives = 163/415 (39%), Gaps = 43/415 (10%) Query: 86 SIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIM 145 + F G LVG + + GR+ LL +S +L S + ++ M + R + Sbjct: 147 TFFFAGVLVGAVAFGYLSDRFGRRRLLLVAY---VSTLVLGLASAASVSYVMFAITRTLT 203 Query: 146 GID-GGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPY 204 G G + V+P+ L + E R G +++ F GV LL L L ++ W + Sbjct: 204 GSALAGFTIIVMPLELEWLDV-EHRTVAGVLSSTFWTGGVM---LLALVGYLIRD--WRW 257 Query: 205 LFGVIVVPAVVQLLSLPFLPDSPRYLLLEKH-NEARAVKAFQTFLGKADVSQEVEEVLAE 263 L + +P +LSL ++P+S R+LL + H EA L V ++ A Sbjct: 258 LLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAV 317 Query: 264 SRV---QRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIP 320 S+V +R +R S L+L R P +R +++ C +WF N + + Sbjct: 318 SKVAAGERVVRRPSYLDLFRTPRLRH------ISLCCV------VVWFGVNFSYYGLSLD 365 Query: 321 PA----KIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQ 376 + + L G +E + + L + + GRR G L FGT L Sbjct: 366 VSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTR--LLVSS 423 Query: 377 DHAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAV 436 D W L+++G A+F + ++ T E + R + V L Sbjct: 424 DMKSWSTVLAVMGKAFSEAAFTTA-----YLFTSELYPTVLRQTGMGLTALVGRLGGSLA 478 Query: 437 GL--LFPFIQKSLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRN 489 L L + SL + A + A+ +LPET+ E Q +++ Sbjct: 479 PLAALLDGVWLSLPKLTYGGIALLAAGTAL----LLPETRQAQLPETIQDVERKS 529 >gi|213021148 SVOP-like isoform 1 [Homo sapiens] Length = 492 Score = 54.3 bits (129), Expect = 3e-07 Identities = 94/429 (21%), Positives = 175/429 (40%), Gaps = 56/429 (13%) Query: 83 VTVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALL--MACSLQAGAFEMLIV 140 VT +F G +V +++ ++ GR LL + + +LL A S F +V Sbjct: 89 VTTMVF-FGYMVFSILFGLLADRYGRWKILLISFLWGAYFSLLTSFAPSYIWFVFLRTMV 147 Query: 141 GRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKES 200 G + G G+ + +E P + RG + ++ +F G ++GL ++ Sbjct: 148 GCGVSGHSQGLIIK------TEFLPTKYRGYMLPLSQVFWLAGSLL--IIGLASVIIPTI 199 Query: 201 TWPYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEV 260 W +L V +P ++ +++ F+P+S R+ + RA A + K + S E Sbjct: 200 GWRWLIRVASIPGIILIVAFKFIPESARFNV--STGNTRAALATLERVAKMNRSVMPEGK 257 Query: 261 LAESRVQRSIRLVSVLE--LLRAPYVRWQVVTVIVTMACY-------------QLCG--L 303 L E +++ R +L+ LR W V+ + ++ A Y +CG Sbjct: 258 LVEPVLEKRGRFADLLDAKYLRTTLQIW-VIWLGISFAYYGVILASAELLERDLVCGSKS 316 Query: 304 NAIWFYTNSIFGKAGIP-------PAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLI 356 ++ T G++ P P+ + +ST G E + L I LGRR L Sbjct: 317 DSAVVVTGGDSGESQSPCYCHMFAPSDYRTMIISTIG-EIALNPLNILGINFLGRRLSLS 375 Query: 357 GGFGLMGLFFGTLTITLTLQDHAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQS 416 G LFF L I + ++G L ++ + + +I T E + + Sbjct: 376 ITMGCTALFFLLLNICTS---------SAGLIGFLFMLRALVAANFNTVYIYTAEVYPTT 426 Query: 417 QRPAAFIIAGTVNWLSNFAVGLLFPFIQKSLDTYCFL----VFATICITGAIYLYFVLPE 472 R +G++ + ++ PFI + L + L +F+++C+ AI + + E Sbjct: 427 MRALGMGTSGSLCRIG----AMVAPFISQVLMSASILGALCLFSSVCVVCAISAFTLPIE 482 Query: 473 TKNRTYAEI 481 TK R +I Sbjct: 483 TKGRALQQI 491 >gi|24497476 solute carrier family 22 member 6 isoform b [Homo sapiens] Length = 550 Score = 53.5 bits (127), Expect = 4e-07 Identities = 89/422 (21%), Positives = 168/422 (39%), Gaps = 57/422 (13%) Query: 86 SIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIM 145 S++ +G L+G ++ + LGR+ L+ N + A+ C+ A F + R + Sbjct: 139 SLYMVGVLLGAMVFGYLADRLGRRKVLILN---YLQTAVSGTCAAFAPNFPIYCAFRLLS 195 Query: 146 GID-GGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVF--TGQLLGLPELLGKESTW 202 G+ G++L+ + + + E P R +G + +G F G +P W Sbjct: 196 GMALAGISLNCMTLNV-EWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPH-------W 247 Query: 203 PYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNE--ARAVKAFQTFLGKADVSQEVEEV 260 +L ++ P + F +S R+ + RA++ GK + ++ Sbjct: 248 RHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSME 307 Query: 261 LAESRVQRSIRL----VSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGK 316 + + +Q+ + + S +ELLR P T+ LC L+ +WF T+ F Sbjct: 308 VLRASLQKELTMGKGQASAMELLRCP-----------TLRHLFLC-LSMLWFATS--FAY 353 Query: 317 AGIP------PAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLT 370 G+ I + + G ++ A + LVI LGRRP + L G+ L Sbjct: 354 YGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICI--LL 411 Query: 371 ITLTLQDHAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNW 430 + QD + L+++G + ASF F+ TGE + R + T+ Sbjct: 412 NGVIPQDQSIVRTSLAVLGKGCLAASF-----NCIFLYTGELYPTMIRQTGMGMGSTMAR 466 Query: 431 LSNFAVGLLFPFIQKSLDTY----CFLVFATICITGAIYLYFVLPETKNRTYAEISQAFS 486 + + ++ P + + + Y F+ A A+ + +LPET + + Q Sbjct: 467 VGS----IVSPLVSMTAELYPSMPLFIYGAVPVAASAVTV--LLPETLGQPLPDTVQDLE 520 Query: 487 KR 488 R Sbjct: 521 SR 522 >gi|20070188 solute carrier family 22 member 6 isoform a [Homo sapiens] Length = 563 Score = 53.5 bits (127), Expect = 4e-07 Identities = 89/422 (21%), Positives = 168/422 (39%), Gaps = 57/422 (13%) Query: 86 SIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIM 145 S++ +G L+G ++ + LGR+ L+ N + A+ C+ A F + R + Sbjct: 139 SLYMVGVLLGAMVFGYLADRLGRRKVLILN---YLQTAVSGTCAAFAPNFPIYCAFRLLS 195 Query: 146 GID-GGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVF--TGQLLGLPELLGKESTW 202 G+ G++L+ + + + E P R +G + +G F G +P W Sbjct: 196 GMALAGISLNCMTLNV-EWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPH-------W 247 Query: 203 PYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNE--ARAVKAFQTFLGKADVSQEVEEV 260 +L ++ P + F +S R+ + RA++ GK + ++ Sbjct: 248 RHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSME 307 Query: 261 LAESRVQRSIRL----VSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGK 316 + + +Q+ + + S +ELLR P T+ LC L+ +WF T+ F Sbjct: 308 VLRASLQKELTMGKGQASAMELLRCP-----------TLRHLFLC-LSMLWFATS--FAY 353 Query: 317 AGIP------PAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLT 370 G+ I + + G ++ A + LVI LGRRP + L G+ L Sbjct: 354 YGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICI--LL 411 Query: 371 ITLTLQDHAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNW 430 + QD + L+++G + ASF F+ TGE + R + T+ Sbjct: 412 NGVIPQDQSIVRTSLAVLGKGCLAASF-----NCIFLYTGELYPTMIRQTGMGMGSTMAR 466 Query: 431 LSNFAVGLLFPFIQKSLDTY----CFLVFATICITGAIYLYFVLPETKNRTYAEISQAFS 486 + + ++ P + + + Y F+ A A+ + +LPET + + Q Sbjct: 467 VGS----IVSPLVSMTAELYPSMPLFIYGAVPVAASAVTV--LLPETLGQPLPDTVQDLE 520 Query: 487 KR 488 R Sbjct: 521 SR 522 >gi|24497480 solute carrier family 22 member 6 isoform d [Homo sapiens] Length = 519 Score = 52.8 bits (125), Expect = 8e-07 Identities = 78/358 (21%), Positives = 145/358 (40%), Gaps = 47/358 (13%) Query: 86 SIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIM 145 S++ +G L+G ++ + LGR+ L+ N + A+ C+ A F + R + Sbjct: 139 SLYMVGVLLGAMVFGYLADRLGRRKVLILN---YLQTAVSGTCAAFAPNFPIYCAFRLLS 195 Query: 146 GID-GGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVF--TGQLLGLPELLGKESTW 202 G+ G++L+ + + + E P R +G + +G F G +P W Sbjct: 196 GMALAGISLNCMTLNV-EWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPH-------W 247 Query: 203 PYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNE--ARAVKAFQTFLGKADVSQEVEEV 260 +L ++ P + F +S R+ + RA++ GK + ++ Sbjct: 248 RHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSME 307 Query: 261 LAESRVQRSIRL----VSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGK 316 + + +Q+ + + S +ELLR P T+ LC L+ +WF T+ F Sbjct: 308 VLRASLQKELTMGKGQASAMELLRCP-----------TLRHLFLC-LSMLWFATS--FAY 353 Query: 317 AGIP------PAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLT 370 G+ I + + G ++ A + LVI LGRRP + L G+ L Sbjct: 354 YGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICI--LL 411 Query: 371 ITLTLQDHAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTV 428 + QD + L+++G + ASF F+ TGE + R ++ T+ Sbjct: 412 NGVIPQDQSIVRTSLAVLGKGCLAASF-----NCIFLYTGELYPTMIRAVTVLLPETL 464 >gi|24497478 solute carrier family 22 member 6 isoform c [Homo sapiens] Length = 506 Score = 52.8 bits (125), Expect = 8e-07 Identities = 78/358 (21%), Positives = 145/358 (40%), Gaps = 47/358 (13%) Query: 86 SIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIM 145 S++ +G L+G ++ + LGR+ L+ N + A+ C+ A F + R + Sbjct: 139 SLYMVGVLLGAMVFGYLADRLGRRKVLILN---YLQTAVSGTCAAFAPNFPIYCAFRLLS 195 Query: 146 GID-GGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVF--TGQLLGLPELLGKESTW 202 G+ G++L+ + + + E P R +G + +G F G +P W Sbjct: 196 GMALAGISLNCMTLNV-EWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPH-------W 247 Query: 203 PYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNE--ARAVKAFQTFLGKADVSQEVEEV 260 +L ++ P + F +S R+ + RA++ GK + ++ Sbjct: 248 RHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSME 307 Query: 261 LAESRVQRSIRL----VSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGK 316 + + +Q+ + + S +ELLR P T+ LC L+ +WF T+ F Sbjct: 308 VLRASLQKELTMGKGQASAMELLRCP-----------TLRHLFLC-LSMLWFATS--FAY 353 Query: 317 AGIP------PAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLT 370 G+ I + + G ++ A + LVI LGRRP + L G+ L Sbjct: 354 YGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICI--LL 411 Query: 371 ITLTLQDHAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTV 428 + QD + L+++G + ASF F+ TGE + R ++ T+ Sbjct: 412 NGVIPQDQSIVRTSLAVLGKGCLAASF-----NCIFLYTGELYPTMIRAVTVLLPETL 464 >gi|7662270 synaptic vesicle protein 2B homolog [Homo sapiens] Length = 683 Score = 52.0 bits (123), Expect = 1e-06 Identities = 49/164 (29%), Positives = 72/164 (43%), Gaps = 15/164 (9%) Query: 87 IFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMG 146 I +G + G I+ + LGRK L + S A L + GAF + R I G Sbjct: 153 IVYLGMMAGAFILGGLADKLGRKRVLSMSLAVNASFASLSSFVQGYGAF---LFCRLISG 209 Query: 147 IDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLG---LPEL-----LGK 198 I G AL ++ Y SE +E RG IF G + +P +G Sbjct: 210 IGIGGALPIVFAYFSEFLSREKRGEHLSWLGIFWMTGGLYASAMAWSIIPHYGWGFSMGT 269 Query: 199 E---STWPYLFGVIVVPAVVQLLSLPFLPDSPRYLL-LEKHNEA 238 +W V +P V +++L F+P+SPR+LL + KH+EA Sbjct: 270 NYHFHSWRVFVIVCALPCTVSMVALKFMPESPRFLLEMGKHDEA 313 >gi|33457322 SVOP-like isoform 2 [Homo sapiens] Length = 340 Score = 52.0 bits (123), Expect = 1e-06 Identities = 76/349 (21%), Positives = 143/349 (40%), Gaps = 47/349 (13%) Query: 161 SEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGVIVVPAVVQLLSL 220 +E P + RG + ++ +F G ++GL ++ W +L V +P ++ +++ Sbjct: 10 TEFLPTKYRGYMLPLSQVFWLAGSLL--IIGLASVIIPTIGWRWLIRVASIPGIILIVAF 67 Query: 221 PFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQRSIRLVSVLE--L 278 F+P+S R+ + RA A + K + S E L E +++ R +L+ Sbjct: 68 KFIPESARFNV--STGNTRAALATLERVAKMNRSVMPEGKLVEPVLEKRGRFADLLDAKY 125 Query: 279 LRAPYVRWQVVTVIVTMACY-------------QLCG--LNAIWFYTNSIFGKAGIP--- 320 LR W V+ + ++ A Y +CG ++ T G++ P Sbjct: 126 LRTTLQIW-VIWLGISFAYYGVILASAELLERDLVCGSKSDSAVVVTGGDSGESQSPCYC 184 Query: 321 ----PAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQ 376 P+ + +ST G E + L I LGRR L G LFF L I + Sbjct: 185 HMFAPSDYRTMIISTIG-EIALNPLNILGINFLGRRLSLSITMGCTALFFLLLNICTS-- 241 Query: 377 DHAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAV 436 ++G L ++ + + +I T E + + R +G++ + Sbjct: 242 -------SAGLIGFLFMLRALVAANFNTVYIYTAEVYPTTMRALGMGTSGSLCRIG---- 290 Query: 437 GLLFPFIQKSLDTYCFL----VFATICITGAIYLYFVLPETKNRTYAEI 481 ++ PFI + L + L +F+++C+ AI + + ETK R +I Sbjct: 291 AMVAPFISQVLMSASILGALCLFSSVCVVCAISAFTLPIETKGRALQQI 339 >gi|11415038 solute carrier family 22 member 3 [Homo sapiens] Length = 556 Score = 51.6 bits (122), Expect = 2e-06 Identities = 92/403 (22%), Positives = 164/403 (40%), Gaps = 48/403 (11%) Query: 83 VTVSIFAIGGLVGTLIVKMIGKVLGRKHT-LLANNGFAISAALLMACSLQAGAFEMLIVG 141 +T +I +G L G + GR LL+ G ++ ++ A F + ++ Sbjct: 156 LTQAILNLGFLTGAFTLGYAADRYGRIVIYLLSCLGVGVTGVVVAF----APNFPVFVIF 211 Query: 142 RFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKEST 201 RF+ G+ G + ++EI + R +G V +F +G+ LP + Sbjct: 212 RFLQGVFGKGTWMTCYVIVTEIVGSKQRRIVGIVIQMFFTLGIII-----LPGIAYFIPN 266 Query: 202 WPYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNE--ARAVKAFQTFLGKADVSQEVEE 259 W + I +P+ + LL +P+SPR+L+ K + + ++ GK S E Sbjct: 267 WQGIQLAITLPSFLFLLYYWVVPESPRWLITRKKGDKALQILRRIAKCNGKYLSSNYSEI 326 Query: 260 VLAESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFG---- 315 + + V S L+L+R P +R T+I+ A WF + ++ Sbjct: 327 TVTDEEVSNP----SFLDLVRTPQMR--KCTLILMFA----------WFTSAVVYQGLVM 370 Query: 316 KAGIPPAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTL 375 + GI + +G +E A+ L IE LGRR + G+ +T L Sbjct: 371 RLGIIGGNLYIDFFISGVVELPGALLILLTIERLGRRLPFAASNIVAGV---ACLVTAFL 427 Query: 376 QDHAPWV-PYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRP-AAFIIAGTVNWLSN 433 + W+ ++ +G L I +F I +++ E + + R + +G ++ Sbjct: 428 PEGIAWLRTTVATLGRLGITMAF-----EIVYLVNSELYPTTLRNFGVSLCSGLCDFGGI 482 Query: 434 FAVGLLFPF--IQKSLDTYCFLVFATICITGAIYLYFVLPETK 474 A LLF + L F + A+IC G L +LPETK Sbjct: 483 IAPFLLFRLAAVWLELPLIIFGILASIC--GG--LVMLLPETK 521 >gi|239751156 PREDICTED: hypothetical protein LOC146429 isoform 6 [Homo sapiens] Length = 560 Score = 51.2 bits (121), Expect = 2e-06 Identities = 116/448 (25%), Positives = 182/448 (40%), Gaps = 56/448 (12%) Query: 54 PYIKAFYNESWERRHGRPIDPDTLTLL----WSVTVSIFA--IGGLVGTLIVKMIGKVLG 107 P +A SW G P T L+ W V + + +G L+G +I+ G Sbjct: 99 PLTRAPRPSSWASCSGAAAGP-TWNLVCGDGWKVPLEQVSHLLGWLLGCVILGAGCDRFG 157 Query: 108 RKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGIDGGVALSVLPMYLSEIS--- 164 R+ +A+ + L A A +F L+V R + G G +A ++L +YL+ + Sbjct: 158 RRAVFVAS---LVLTTGLGASEALAASFPTLLVLRLLHG--GTLAGALLALYLARLELCD 212 Query: 165 -PKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGVIVVPAVVQLLSLPF- 222 P + S+G +F +G L LP L W L G+ + + + LL F Sbjct: 213 PPHRLAFSMG--AGLFSVVGT-----LLLPGLAALVQDWRLLQGLGALMSGLLLLFWGFP 265 Query: 223 --LPDSPRYLLLEKHNEARAVKAFQTF-----LGKADVSQE------VEEVLAESRVQRS 269 P+SP +LL ARA K F +G D S E E+ S Sbjct: 266 ALFPESPCWLLATGQ-VARARKILWRFAEASGVGPGDSSLEENSLATATELTMLSARSPQ 324 Query: 270 IRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYVTL 329 R S L LLR V W+ ++ L G + S+ + +P +PY Sbjct: 325 PRYHSPLGLLRTR-VTWRNGLIL---GFSSLVGGGIRASFRRSLAPQ--VPTFYLPYFL- 377 Query: 330 STGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPW-VPYLSIV 388 G+E A VF L + GRRP+L+ G + GL +L + Q W V +LS++ Sbjct: 378 -EAGLEAAALVFLLLTADCCGRRPVLLLGTMVTGL--ASLLLLAGAQYLPGWTVLFLSVL 434 Query: 389 GILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKSLD 448 G+LA A + + E F R A + +L A GLL + Sbjct: 435 GLLASRA-----VSALSSLFAAEVFPTVIRGAGLGLVLGAGFLGQ-AAGLLDTLHGRQGF 488 Query: 449 TYCFLVFATICITGAIYLYFVLPETKNR 476 +VFA++ + A+ +LPE+++R Sbjct: 489 FLQQVVFASLAVL-ALLCVLLLPESRSR 515 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.324 0.141 0.426 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,333,811 Number of Sequences: 37866 Number of extensions: 773181 Number of successful extensions: 2251 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 34 Number of HSP's successfully gapped in prelim test: 34 Number of HSP's that attempted gapping in prelim test: 2157 Number of HSP's gapped (non-prelim): 79 length of query: 511 length of database: 18,247,518 effective HSP length: 107 effective length of query: 404 effective length of database: 14,195,856 effective search space: 5735125824 effective search space used: 5735125824 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.5 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.