Guide to the Human Genome
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Search of human proteins with 47933387

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|47933387 solute carrier family 2, member 9 protein isoform 1
[Homo sapiens]
         (540 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|47933387 solute carrier family 2, member 9 protein isoform 1 ...  1075   0.0  
gi|47933389 solute carrier family 2, member 9 protein isoform 2 ...   974   0.0  
gi|4507013 solute carrier family 2 (facilitated glucose/fructose...   435   e-122
gi|134053883 intestinal facilitative glucose transporter 7 [Homo...   431   e-121
gi|190684655 glucose transporter protein 10 isoform a [Homo sapi...   389   e-108
gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens]   389   e-108
gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens]   389   e-108
gi|166795299 solute carrier family 2 (facilitated glucose transp...   365   e-101
gi|4507011 glucose transporter 4 [Homo sapiens]                       339   4e-93
gi|5902090 solute carrier family 2 (facilitated glucose transpor...   323   2e-88
gi|23592238 glucose transporter 14 [Homo sapiens]                     323   3e-88
gi|4557851 solute carrier family 2 (facilitated glucose transpor...   259   4e-69
gi|207447703 solute carrier family 2 (facilitated glucose/fructo...   165   1e-40
gi|223029432 solute carrier family 2 (facilitated glucose transp...   138   1e-32
gi|21361449 solute carrier family 2 (facilitated glucose transpo...   137   3e-32
gi|223029430 solute carrier family 2 (facilitated glucose transp...   127   2e-29
gi|203098995 solute carrier family 2 (facilitated glucose transp...   115   1e-25
gi|21553331 solute carrier family 2 (facilitated glucose transpo...    91   3e-18
gi|13540547 solute carrier family 2 member 10 [Homo sapiens]           68   2e-11
gi|90669191 solute carrier family 22 member 7 isoform b [Homo sa...    60   7e-09
gi|24497497 solute carrier family 22 member 7 isoform a [Homo sa...    60   7e-09
gi|24497476 solute carrier family 22 member 6 isoform b [Homo sa...    55   1e-07
gi|20070188 solute carrier family 22 member 6 isoform a [Homo sa...    55   1e-07
gi|24497480 solute carrier family 22 member 6 isoform d [Homo sa...    55   2e-07
gi|24497478 solute carrier family 22 member 6 isoform c [Homo sa...    55   2e-07
gi|213021148 SVOP-like isoform 1 [Homo sapiens]                        54   3e-07
gi|7662270 synaptic vesicle protein 2B homolog [Homo sapiens]          52   1e-06
gi|33457322 SVOP-like isoform 2 [Homo sapiens]                         52   1e-06
gi|11415038 solute carrier family 22 member 3 [Homo sapiens]           52   2e-06
gi|239751156 PREDICTED: hypothetical protein LOC146429 isoform 6...    51   2e-06

>gi|47933387 solute carrier family 2, member 9 protein isoform 1
           [Homo sapiens]
          Length = 540

 Score = 1075 bits (2781), Expect = 0.0
 Identities = 540/540 (100%), Positives = 540/540 (100%)

Query: 1   MARKQNRNSKELGLVPLTDDTSHAGPPGPGRALLECDHLRSGVPGGRRRKDWSCSLLVAS 60
           MARKQNRNSKELGLVPLTDDTSHAGPPGPGRALLECDHLRSGVPGGRRRKDWSCSLLVAS
Sbjct: 1   MARKQNRNSKELGLVPLTDDTSHAGPPGPGRALLECDHLRSGVPGGRRRKDWSCSLLVAS 60

Query: 61  LAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVSIFAIG 120
           LAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVSIFAIG
Sbjct: 61  LAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVSIFAIG 120

Query: 121 GLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGIDGGV 180
           GLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGIDGGV
Sbjct: 121 GLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGIDGGV 180

Query: 181 ALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGVIVV 240
           ALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGVIVV
Sbjct: 181 ALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGVIVV 240

Query: 241 PAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQRSIR 300
           PAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQRSIR
Sbjct: 241 PAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQRSIR 300

Query: 301 LVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYVTLST 360
           LVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYVTLST
Sbjct: 301 LVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYVTLST 360

Query: 361 GGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLSIVGIL 420
           GGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLSIVGIL
Sbjct: 361 GGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLSIVGIL 420

Query: 421 AIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKSLDTYC 480
           AIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKSLDTYC
Sbjct: 421 AIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKSLDTYC 480

Query: 481 FLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNKAYPPEEKIDSAVTDGKINGRP 540
           FLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNKAYPPEEKIDSAVTDGKINGRP
Sbjct: 481 FLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNKAYPPEEKIDSAVTDGKINGRP 540


>gi|47933389 solute carrier family 2, member 9 protein isoform 2
           [Homo sapiens]
          Length = 511

 Score =  974 bits (2517), Expect = 0.0
 Identities = 490/494 (99%), Positives = 493/494 (99%)

Query: 47  RRRKDWSCSLLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTL 106
           +++ DWSCSLLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTL
Sbjct: 18  KKKLDWSCSLLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTL 77

Query: 107 TLLWSVTVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEM 166
           TLLWSVTVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEM
Sbjct: 78  TLLWSVTVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEM 137

Query: 167 LIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLG 226
           LIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLG
Sbjct: 138 LIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLG 197

Query: 227 KESTWPYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEV 286
           KESTWPYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEV
Sbjct: 198 KESTWPYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEV 257

Query: 287 EEVLAESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKA 346
           EEVLAESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKA
Sbjct: 258 EEVLAESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKA 317

Query: 347 GIPPAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQD 406
           GIPPAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQD
Sbjct: 318 GIPPAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQD 377

Query: 407 HAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVG 466
           HAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVG
Sbjct: 378 HAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVG 437

Query: 467 LLFPFIQKSLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNKAYPPEEK 526
           LLFPFIQKSLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNKAYPPEEK
Sbjct: 438 LLFPFIQKSLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNKAYPPEEK 497

Query: 527 IDSAVTDGKINGRP 540
           IDSAVTDGKINGRP
Sbjct: 498 IDSAVTDGKINGRP 511


>gi|4507013 solute carrier family 2 (facilitated glucose/fructose
           transporter), member 5 isoform 1 [Homo sapiens]
          Length = 501

 Score =  435 bits (1119), Expect = e-122
 Identities = 218/475 (45%), Positives = 312/475 (65%), Gaps = 3/475 (0%)

Query: 56  LLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVS 115
           L +A+L  AFGSSF YGYN++ VN+P   ++ FYNE++  R G  ++   LTLLWSVTVS
Sbjct: 17  LALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLLWSVTVS 76

Query: 116 IFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMG 175
           +F  GG +G+L+V  +    GRK  LL NN F+I  A+LM CS  A +FE++I+ R ++G
Sbjct: 77  MFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLVG 136

Query: 176 IDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLF 235
           I  GV+ +V+PMYL E++PK +RG+LG V  +FI +G+   Q+ GL  LL     WP L 
Sbjct: 137 ICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPILL 196

Query: 236 GVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRV 295
           G+  VPA +QLL LPF P+SPRYLL++K +EA A KA QT  G   V +EV E+  E   
Sbjct: 197 GLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVAEIRQEDEA 256

Query: 296 QRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPY 355
           +++   +SVL+L R   +RWQ++++IV M   QL G+NAI++Y + I+  AG+P   + Y
Sbjct: 257 EKAAGFISVLKLFRMRSLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGVPEEHVQY 316

Query: 356 VTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLS 415
           VT  TG +  +    +  V+E LGRR LL+ GF +  +    LT  L LQD   W+PY+S
Sbjct: 317 VTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSICLIACCVLTAALALQDTVSWMPYIS 376

Query: 416 IVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKS 475
           IV +++ +     GP  IP +L  E F QS RP+AF++ G+V+WLSNF VGL+FPFIQ+ 
Sbjct: 377 IVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTVGLIFPFIQEG 436

Query: 476 LDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNK---AYPPEEKI 527
           L  Y F+VFA IC+   IY++ ++PETK +T+ EI+Q F+K NK    YP +E++
Sbjct: 437 LGPYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIFTKMNKVSEVYPEKEEL 491


>gi|134053883 intestinal facilitative glucose transporter 7 [Homo
           sapiens]
          Length = 512

 Score =  431 bits (1109), Expect = e-121
 Identities = 212/472 (44%), Positives = 316/472 (66%)

Query: 55  SLLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTV 114
           +LL+A+L+ AFGS+F YGYNLSVVN P    K+FYNE++  RH   +D   + LLWS TV
Sbjct: 22  TLLLATLSAAFGSAFQYGYNLSVVNTPHKVFKSFYNETYFERHATFMDGKLMLLLWSCTV 81

Query: 115 SIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIM 174
           S+F +GGL+G+L+V ++    GRK TLL NN FAI  A+LM  S  A AFE+++  R ++
Sbjct: 82  SMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVAKAFELIVFSRVVL 141

Query: 175 GIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYL 234
           G+  G++ S LPMYL E++PK +RG +G +T +F+ +GVF  Q+  L  +LG  + WP L
Sbjct: 142 GVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSLQAILGNPAGWPVL 201

Query: 235 FGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESR 294
             +  VPA++QLL+LPF P+SPRY L++K +EA A +A +   G  D+  E+E++ AE+R
Sbjct: 202 LALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTDMEAELEDMRAEAR 261

Query: 295 VQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIP 354
            +R+   +SVL L     +RWQ++++IV MA  QL G+NAI +Y ++I+  AG+  A   
Sbjct: 262 AERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAINYYADTIYTSAGVEAAHSQ 321

Query: 355 YVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYL 414
           YVT+ +G +  +  + S +++E LGRR LL+ G+G+ G     LT+ L  Q+  P + YL
Sbjct: 322 YVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQNRVPELSYL 381

Query: 415 SIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQK 474
            I+ + A IA    GP  +P ++  E F QS R AAF++ G V+WL+NF +G LFP IQ+
Sbjct: 382 GIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFLFPSIQE 441

Query: 475 SLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNKAYPPEEK 526
           ++  Y F++FA IC+  AIY+Y V+PETK +T+ EI++ F+KRN+   PEEK
Sbjct: 442 AIGAYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAKRNRVKLPEEK 493


>gi|190684655 glucose transporter protein 10 isoform a [Homo
           sapiens]
          Length = 503

 Score =  389 bits (1000), Expect = e-108
 Identities = 195/463 (42%), Positives = 289/463 (62%)

Query: 56  LLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVS 115
           LL+   A   G +F +GYNLS++NAPT +I+ F NE+W+ R G P+    + L+WS+ VS
Sbjct: 20  LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVS 79

Query: 116 IFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMG 175
           ++ +GGL G L+   +   LGRK +LL NN F +SAA+L   S +AG+FEM+++GR ++G
Sbjct: 80  LYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG 139

Query: 176 IDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLF 235
           ++ GV++++ PMYL E +PKE+RG++   +AIF  +G+  GQ++GL ELLG    WP L 
Sbjct: 140 VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLL 199

Query: 236 GVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRV 295
              +VP  +QL SLP LP+SPRYLL++  +    + A +   G  D++ E+EE+  E   
Sbjct: 200 ASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAA 259

Query: 296 QRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPY 355
            +  R     EL +   +R QV +++V  +  +LCG ++++ Y +S+F KAG+P AKI Y
Sbjct: 260 CQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQY 319

Query: 356 VTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLS 415
             + TG  E L AV S +VIE +GRR LLIGG+ LM  +    T+ L LQ   PW  YL+
Sbjct: 320 AIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYLA 379

Query: 416 IVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKS 475
           +  I A I SF  GP G+  IL  E F Q  RPAA ++ G + W+    VGL FPFI ++
Sbjct: 380 MACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEA 439

Query: 476 LDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRN 518
           L  + ++ F  +C+ GAIY    LPETK +T+ EIS+   + N
Sbjct: 440 LSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLN 482


>gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens]
          Length = 496

 Score =  389 bits (1000), Expect = e-108
 Identities = 195/463 (42%), Positives = 289/463 (62%)

Query: 56  LLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVS 115
           LL+   A   G +F +GYNLS++NAPT +I+ F NE+W+ R G P+    + L+WS+ VS
Sbjct: 13  LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVS 72

Query: 116 IFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMG 175
           ++ +GGL G L+   +   LGRK +LL NN F +SAA+L   S +AG+FEM+++GR ++G
Sbjct: 73  LYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG 132

Query: 176 IDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLF 235
           ++ GV++++ PMYL E +PKE+RG++   +AIF  +G+  GQ++GL ELLG    WP L 
Sbjct: 133 VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLL 192

Query: 236 GVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRV 295
              +VP  +QL SLP LP+SPRYLL++  +    + A +   G  D++ E+EE+  E   
Sbjct: 193 ASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAA 252

Query: 296 QRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPY 355
            +  R     EL +   +R QV +++V  +  +LCG ++++ Y +S+F KAG+P AKI Y
Sbjct: 253 CQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQY 312

Query: 356 VTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLS 415
             + TG  E L AV S +VIE +GRR LLIGG+ LM  +    T+ L LQ   PW  YL+
Sbjct: 313 AIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYLA 372

Query: 416 IVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKS 475
           +  I A I SF  GP G+  IL  E F Q  RPAA ++ G + W+    VGL FPFI ++
Sbjct: 373 MACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEA 432

Query: 476 LDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRN 518
           L  + ++ F  +C+ GAIY    LPETK +T+ EIS+   + N
Sbjct: 433 LSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLN 475


>gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens]
          Length = 499

 Score =  389 bits (1000), Expect = e-108
 Identities = 195/463 (42%), Positives = 289/463 (62%)

Query: 56  LLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVS 115
           LL+   A   G +F +GYNLS++NAPT +I+ F NE+W+ R G P+    + L+WS+ VS
Sbjct: 16  LLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSLIVS 75

Query: 116 IFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMG 175
           ++ +GGL G L+   +   LGRK +LL NN F +SAA+L   S +AG+FEM+++GR ++G
Sbjct: 76  LYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRLLVG 135

Query: 176 IDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLF 235
           ++ GV++++ PMYL E +PKE+RG++   +AIF  +G+  GQ++GL ELLG    WP L 
Sbjct: 136 VNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWPLLL 195

Query: 236 GVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRV 295
              +VP  +QL SLP LP+SPRYLL++  +    + A +   G  D++ E+EE+  E   
Sbjct: 196 ASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEERAA 255

Query: 296 QRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPY 355
            +  R     EL +   +R QV +++V  +  +LCG ++++ Y +S+F KAG+P AKI Y
Sbjct: 256 CQGCRARRPWELFQHRALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEAKIQY 315

Query: 356 VTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLS 415
             + TG  E L AV S +VIE +GRR LLIGG+ LM  +    T+ L LQ   PW  YL+
Sbjct: 316 AIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLMTCWGSIFTVALCLQSSFPWTLYLA 375

Query: 416 IVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKS 475
           +  I A I SF  GP G+  IL  E F Q  RPAA ++ G + W+    VGL FPFI ++
Sbjct: 376 MACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFIMEA 435

Query: 476 LDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRN 518
           L  + ++ F  +C+ GAIY    LPETK +T+ EIS+   + N
Sbjct: 436 LSHFLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLN 478


>gi|166795299 solute carrier family 2 (facilitated glucose
           transporter), member 1 [Homo sapiens]
          Length = 492

 Score =  365 bits (936), Expect = e-101
 Identities = 188/484 (38%), Positives = 289/484 (59%), Gaps = 7/484 (1%)

Query: 57  LVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVSI 116
           L+ ++ GA   S  +GYN  V+NAP   I+ FYN++W  R+G  I P TLT LWS++V+I
Sbjct: 12  LMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTTLTTLWSLSVAI 71

Query: 117 FAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGI 176
           F++GG++G+  V +     GR++++L  N  A  +A+LM  S    +FEMLI+GRFI+G+
Sbjct: 72  FSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGV 131

Query: 177 DGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFG 236
             G+    +PMY+ E+SP  +RG+LG +  + I +G+   Q+ GL  ++G +  WP L  
Sbjct: 132 YCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLS 191

Query: 237 VIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQ 296
           +I +PA++Q + LPF P+SPR+LL+ ++ E RA    +   G ADV+ +++E+  ESR  
Sbjct: 192 IIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMKEESRQM 251

Query: 297 RSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYV 356
              + V++LEL R+P  R  ++  +V     QL G+NA+++Y+ SIF KAG+   +  Y 
Sbjct: 252 MREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGV--QQPVYA 309

Query: 357 TLSTGGIETLAAVFSGLVIEHLGRRPL-LIGGFGLMGLFFGTLTITLTLQDHAPWVPYLS 415
           T+ +G + T   V S  V+E  GRR L LIG  G+ G     +TI L L +  PW+ YLS
Sbjct: 310 TIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAI-LMTIALALLEQLPWMSYLS 368

Query: 416 IVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKS 475
           IV I   +A F  GPG IP+ +  E F Q  RPAA  +AG  NW SNF VG+ F ++++ 
Sbjct: 369 IVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQL 428

Query: 476 LDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNKAY---PPEEKIDSAVT 532
              Y F++F  + +   I+ YF +PETK RT+ EI+  F +   +     PEE       
Sbjct: 429 CGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPEELFHPLGA 488

Query: 533 DGKI 536
           D ++
Sbjct: 489 DSQV 492


>gi|4507011 glucose transporter 4 [Homo sapiens]
          Length = 509

 Score =  339 bits (869), Expect = 4e-93
 Identities = 183/475 (38%), Positives = 283/475 (59%), Gaps = 8/475 (1%)

Query: 57  LVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHG----RPIDPDTLTLLWSV 112
           LV ++  A   S  +GYN+ V+NAP   I+  YNE+W  R G      I P TLT LW++
Sbjct: 24  LVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIPPGTLTTLWAL 83

Query: 113 TVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRF 172
           +V+IF++GG++ + ++ +I + LGRK  +L NN  A+    LM  +  A ++EMLI+GRF
Sbjct: 84  SVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILGRF 143

Query: 173 IMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWP 232
           ++G   G+   ++PMY+ EI+P  +RG+LG +  + I IG+   Q+LGL  LLG  S WP
Sbjct: 144 LIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLWP 203

Query: 233 YLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAE 292
            L G+ V+PA++QL+ LPF P+SPRYL + ++ E  A K+ +   G ADVS  + E+  E
Sbjct: 204 LLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADVSGVLAELKDE 263

Query: 293 SRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAK 352
            R     R +S+L+LL +   R  ++  +V     QL G+NA+++Y+ SIF  AG+   +
Sbjct: 264 KRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFETAGV--GQ 321

Query: 353 IPYVTLSTGGIETLAAVFSGLVIEHLGRRPL-LIGGFGLMGLFFGTLTITLTLQDHAPWV 411
             Y T+  G + T+  + S L++E  GRR L L+G  G+ G     +T+ L L +  P +
Sbjct: 322 PAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGMCGCAI-LMTVALLLLERVPAM 380

Query: 412 PYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPF 471
            Y+SIV I   +A F  GPG IP+ +  E F Q  RPAA  +AG  NW SNF +G+ F +
Sbjct: 381 SYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFIIGMGFQY 440

Query: 472 IQKSLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNKAYPPEEK 526
           + +++  Y FL+FA + +   I+ +  +PET+ RT+ +IS AF +       E K
Sbjct: 441 VAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQISAAFHRTPSLLEQEVK 495


>gi|5902090 solute carrier family 2 (facilitated glucose
           transporter), member 3 [Homo sapiens]
          Length = 496

 Score =  323 bits (829), Expect = 2e-88
 Identities = 170/458 (37%), Positives = 262/458 (57%), Gaps = 2/458 (0%)

Query: 57  LVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVSI 116
           L+ ++  A   SF +GYN  V+NAP   IK F N++   +   P     LT LWS++V+I
Sbjct: 10  LIFAITVATIGSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWSLSVAI 69

Query: 117 FAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGI 176
           F++GG++G+  V +     GR++++L  N  A++    M     A + EMLI+GR ++G+
Sbjct: 70  FSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGL 129

Query: 177 DGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFG 236
             G+    +PMY+ EISP  +RG+ G +  + I +G+   Q+ GL  +LG E  WP L G
Sbjct: 130 FCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLG 189

Query: 237 VIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQ 296
             ++PA++Q  +LPF P+SPR+LL+ +  E  A +  Q   G  DVSQ+++E+  ES   
Sbjct: 190 FTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARM 249

Query: 297 RSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYV 356
              + V+VLEL R    R  ++  IV     QL G+NA+++Y+  IF  AG+   +  Y 
Sbjct: 250 SQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGV--QEPIYA 307

Query: 357 TLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLSI 416
           T+  G + T+  V S  ++E  GRR L + G G M      +T++L L+D+   + ++ I
Sbjct: 308 TIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGMSFVCI 367

Query: 417 VGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKSL 476
             IL  +A F  GPG IP+ +  E F Q  RPAA  +AG  NW SNF VGLLFP     L
Sbjct: 368 GAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYL 427

Query: 477 DTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAF 514
             Y F++F    IT   + +F +PET+ RT+ +I++AF
Sbjct: 428 GAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF 465


>gi|23592238 glucose transporter 14 [Homo sapiens]
          Length = 520

 Score =  323 bits (827), Expect = 3e-88
 Identities = 171/458 (37%), Positives = 262/458 (57%), Gaps = 2/458 (0%)

Query: 57  LVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVSI 116
           L+ ++  A   SF +GYN  V+NAP   IK F N++   +   P     LT LWS++V+I
Sbjct: 34  LIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLSVAI 93

Query: 117 FAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGI 176
           F++GG++G+  V +     GR++++L  N  A +   LM     A + EMLI+GR ++G+
Sbjct: 94  FSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGL 153

Query: 177 DGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFG 236
             G+    +PMY+ EISP  +RG+ G +  + I IG+   Q+ GL  +LG E  WP L G
Sbjct: 154 FCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLG 213

Query: 237 VIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQ 296
             ++PA++Q  +LP  P+SPR+LL+ +  E  A +  Q   G  DVSQ+++E+  ES   
Sbjct: 214 FTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEMKDESARM 273

Query: 297 RSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYV 356
              + V+VLEL R    R  ++  IV     QL G+NA+++Y+  IF  AG+   +  Y 
Sbjct: 274 SQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGV--QQPIYA 331

Query: 357 TLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLSI 416
           T+S G + T+  + S  ++E  GRR L + G G M      +T++L L++H   + ++ I
Sbjct: 332 TISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSFVCI 391

Query: 417 VGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKSL 476
             IL  +A F  GPG IP+ +  E F Q  RPAA  +AG  NW SNF VGLLFP     L
Sbjct: 392 GAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYL 451

Query: 477 DTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAF 514
             Y F++F    IT   + +F +PET+ RT+ +I++AF
Sbjct: 452 GAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF 489


>gi|4557851 solute carrier family 2 (facilitated glucose
           transporter), member 2 [Homo sapiens]
          Length = 524

 Score =  259 bits (662), Expect = 4e-69
 Identities = 157/513 (30%), Positives = 257/513 (50%), Gaps = 49/513 (9%)

Query: 57  LVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRH--GRPIDP----------- 103
           LV ++  A   SF +GY++ V+NAP   I + Y      RH  G P+D            
Sbjct: 10  LVFTVITAVLGSFQFGYDIGVINAPQQVIISHY------RHVLGVPLDDRKAINNYVINS 63

Query: 104 ---------------------------DTLTLLWSVTVSIFAIGGLVGTLIVKMIGKVLG 136
                                        +T+LWS++VS FA+GG+  +     +G  LG
Sbjct: 64  TDELPTISYSMNPKPTPWAEEETVAAAQLITMLWSLSVSSFAVGGMTASFFGGWLGDTLG 123

Query: 137 RKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGIDGGVALSVLPMYLSEISPKE 196
           R   +L  N  ++  ALLM  S    +  ++I GR I G+  G+   ++PMY+ EI+P  
Sbjct: 124 RIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTA 183

Query: 197 IRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGVIVVPAVVQLLSLPFLPDSP 256
           +RG+LG    + I  G+   Q++GL  +LG    W  L G+  V A++Q L L F P+SP
Sbjct: 184 LRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRAILQSLLLFFCPESP 243

Query: 257 RYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQRSIRLVSVLELLRAPYVRWQ 316
           RYL ++   E +A ++ +   G  DV++++ E+  E     S + VS+++L      R  
Sbjct: 244 RYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQP 303

Query: 317 VVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYVTLSTGGIETLAAVFSGLVIE 376
           ++  ++     Q  G+N I++Y+ SIF  AGI  +K  Y T+  G +  +    S  ++E
Sbjct: 304 ILVALMLHVAQQFSGINGIFYYSTSIFQTAGI--SKPVYATIGVGAVNMVFTAVSVFLVE 361

Query: 377 HLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLSIVGILAIIASFCSGPGGIPFI 436
             GRR L + G   M +    +++ L L +   W+ Y+S++ I   ++ F  GPG IP+ 
Sbjct: 362 KAGRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEIGPGPIPWF 421

Query: 437 LTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKSLDTYCFLVFATICITGAIYLY 496
           +  EFF Q  RPAA  IA   NW  NF V L F +I      Y F +FA + +   ++ +
Sbjct: 422 MVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGPYVFFLFAGVLLAFTLFTF 481

Query: 497 FVLPETKNRTYAEISQAFSKRN-KAYPPEEKID 528
           F +PETK +++ EI+  F K++  A+ P+  ++
Sbjct: 482 FKVPETKGKSFEEIAAEFQKKSGSAHRPKAAVE 514


>gi|207447703 solute carrier family 2 (facilitated glucose/fructose
           transporter), member 5 isoform 2 [Homo sapiens]
          Length = 244

 Score =  165 bits (417), Expect = 1e-40
 Identities = 82/170 (48%), Positives = 117/170 (68%)

Query: 56  LLVASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVS 115
           L +A+L  AFGSSF YGYN++ VN+P   ++ FYNE++  R G  ++   LTLLWSVTVS
Sbjct: 17  LALATLIAAFGSSFQYGYNVAAVNSPALLMQQFYNETYYGRTGEFMEDFPLTLLWSVTVS 76

Query: 116 IFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMG 175
           +F  GG +G+L+V  +    GRK  LL NN F+I  A+LM CS  A +FE++I+ R ++G
Sbjct: 77  MFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISRLLVG 136

Query: 176 IDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELL 225
           I  GV+ +V+PMYL E++PK +RG+LG V  +FI +G+   Q+ GL  LL
Sbjct: 137 ICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLL 186


>gi|223029432 solute carrier family 2 (facilitated glucose
           transporter), member 6 isoform 1 [Homo sapiens]
          Length = 507

 Score =  138 bits (348), Expect = 1e-32
 Identities = 142/530 (26%), Positives = 227/530 (42%), Gaps = 79/530 (14%)

Query: 26  PPGPGRALLECDHLRSGVPGGRRRKDWSCSLLVASLAGAFGSSFLYGYNLSVVNAPTPYI 85
           PP PG      D  R G    +R       + +A+ A   G+ F +GY L   +   P +
Sbjct: 21  PPSPG------DRARVGTLQNKR-------VFLATFAAVLGN-FSFGYALVYTSPVIPAL 66

Query: 86  KAFYNESWERRHGRPIDPDTLTLLWSVTV---SIFAIGGLVGTLIVKMIGKVLGRKHTLL 142
           +            R +DPD L L  S      S+F +G   G L   ++  +LGRK +++
Sbjct: 67  E------------RSLDPD-LHLTKSQASWFGSVFTLGAAAGGLSAMILNDLLGRKLSIM 113

Query: 143 ANNGFAISAALLMACSLQAGAFEMLIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLG 202
            +   A+ +A   A    A    ML++GR + G  GG+  + +P+Y+SEI+P  +RG+LG
Sbjct: 114 FS---AVPSAAGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALG 170

Query: 203 QVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGVIVVPAVVQLLSLPFLPDSPRYLLLE 262
               +    G  +   LGL  LL     W +L      P ++ +L L F+P+SPR+LL  
Sbjct: 171 ATPQLMAVFGSLSLYALGL--LL----PWRWLAVAGEAPVLIMILLLSFMPNSPRFLLSR 224

Query: 263 KHNEARAVKAFQTFLG-KADVSQEVEEVLAESRVQRSIRLVSVLELLRAPYVRWQVVTVI 321
             +E  A++A     G   DV  E E++  +  V+R    VS  E  RAP+V   +   +
Sbjct: 225 GRDE-EALRALAWLRGTDVDVHWEFEQI--QDNVRRQSSRVSWAE-ARAPHVCRPITVAL 280

Query: 322 VTMACYQLCGLNAIWFYTNSIFGKAGI--PPAKIPYVTLSTGGIETLAAVFSGLVIEHLG 379
           +     QL G+  I  Y  SIF    +  PP     +    G +  L+ + + L ++  G
Sbjct: 281 LMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDDAAI---VGAVRLLSVLIAALTMDLAG 337

Query: 380 RRPLLIGGFGLMGLFFGTLTITLTL------------------------QDHAPWVPYLS 415
           R+ LL     +M  F   LT+ L +                        Q  A    YL+
Sbjct: 338 RKVLLFVSAAIM--FAANLTLGLYIHFGPRPLSPNSTAGLESESWGDLAQPLAAPAGYLT 395

Query: 416 IVGILA---IIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLF-PF 471
           +V +LA    I  +  G G I ++L  E      R  A  +    +WL+ F +   F P 
Sbjct: 396 LVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPV 455

Query: 472 IQKSLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRNKAY 521
           +        F  FA IC+   ++    +PETK R+  +I   F    +++
Sbjct: 456 VSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQIESFFRTGRRSF 505


>gi|21361449 solute carrier family 2 (facilitated glucose
           transporter), member 8 [Homo sapiens]
          Length = 477

 Score =  137 bits (344), Expect = 3e-32
 Identities = 138/518 (26%), Positives = 219/518 (42%), Gaps = 79/518 (15%)

Query: 25  GPPGPGRALLECDHLRSGVPGGRRRKDWSCSLLVASLAGAFGSSFLYGYNLSVVNAPTPY 84
           GPPG               P GRR       + +A+ A A G    +G+ L   +   P 
Sbjct: 14  GPPG------------GSAPRGRR-------VFLAAFAAALGP-LSFGFALGYSSPAIPS 53

Query: 85  IKAFYNESWERRHGRP---IDPDTLTLLWSVTVSIFAIGGLVGTLIVKMIGKVLGRKHTL 141
           ++         R   P   +D    +   +V     A GG++G  +V   G+ L     L
Sbjct: 54  LQ---------RAAPPAPRLDDAAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLS---LL 101

Query: 142 LANNGFAISAALLMACSLQAGAFEMLIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSL 201
           L +  F    A++ A    A    ML+ GR + G+  GVA  V P+Y+SEI+   +RG L
Sbjct: 102 LCSVPFVAGFAVITA----AQDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLL 157

Query: 202 GQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGVIVVPAVVQLLSLPFLPDSPRYLLL 261
           G    + + +G+       L  L G    W +L  +  VP  + LL + F+P++PR+LL 
Sbjct: 158 GSCVQLMVVVGIL------LAYLAGWVLEWRWLAVLGCVPPSLMLLLMCFMPETPRFLLT 211

Query: 262 EKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQRSIRLVSVLELLRAPYVRWQVVTVI 321
           + H    A+ A + FL  ++   E   + AE            L LLR P +    +  +
Sbjct: 212 Q-HRRQEAMAALR-FLWGSEQGWEDPPIGAEQSFH--------LALLRQPGIYKPFIIGV 261

Query: 322 VTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYVTLSTGGIETLAAVFSGLVIEHLGRR 381
             MA  QL G+NA+ FY  +IF +A    + +  V +  G I+ L    + L+++  GRR
Sbjct: 262 SLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVV--GVIQVLFTAVAALIMDRAGRR 319

Query: 382 PLLI---------------------GGFGLMGLFFGTLTITLTLQDHAPWVPYLSIVGIL 420
            LL+                     GG G       +  ++    D +  + +L++  + 
Sbjct: 320 LLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVSAQPVDASVGLAWLAVGSMC 379

Query: 421 AIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKSLDTY- 479
             IA F  G G IP++L  E F    +  A  I    NWL  F V   F  + + L  Y 
Sbjct: 380 LFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYG 439

Query: 480 CFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKR 517
            F + +  CI   ++  F +PETK +T  +I+  F  R
Sbjct: 440 AFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFEGR 477


>gi|223029430 solute carrier family 2 (facilitated glucose
           transporter), member 6 isoform 2 [Homo sapiens]
          Length = 445

 Score =  127 bits (320), Expect = 2e-29
 Identities = 128/503 (25%), Positives = 210/503 (41%), Gaps = 87/503 (17%)

Query: 26  PPGPGRALLECDHLRSGVPGGRRRKDWSCSLLVASLAGAFGSSFLYGYNLSVVNAPTPYI 85
           PP PG      D  R G    +R       + +A+ A   G+ F +GY L   +   P +
Sbjct: 21  PPSPG------DRARVGTLQNKR-------VFLATFAAVLGN-FSFGYALVYTSPVIPAL 66

Query: 86  KAFYNESWERRHGRPIDPDTLTLLWSVTV---SIFAIGGLVGTLIVKMIGKVLGRKHTLL 142
           +            R +DPD L L  S      S+F +G   G L   ++  +LGRK +++
Sbjct: 67  E------------RSLDPD-LHLTKSQASWFGSVFTLGAAAGGLSAMILNDLLGRKLSIM 113

Query: 143 ANNGFAISAALLMACSLQAGAFEMLIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLG 202
            +   A+ +A   A    A    ML++GR + G  GG+  + +P+Y+SEI+P  +RG+LG
Sbjct: 114 FS---AVPSAAGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALG 170

Query: 203 QVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGVIVVPAVVQLLSLPFLPDSPRYLLLE 262
               +    G  +   LGL  LL     W +L      P ++ +L L F+P+SPR+LL  
Sbjct: 171 ATPQLMAVFGSLSLYALGL--LL----PWRWLAVAGEAPVLIMILLLSFMPNSPRFLLSR 224

Query: 263 KHNEARAVKAFQTFLG-KADVSQEVEEVLAESRVQRSIRLVSVLELLRAPYVRWQVVTVI 321
             +E  A++A     G   DV  E E++  +  V+R    VS  E  RAP+V   +   +
Sbjct: 225 GRDE-EALRALAWLRGTDVDVHWEFEQI--QDNVRRQSSRVSWAE-ARAPHVCRPITVAL 280

Query: 322 VTMACYQLCGLNAIWFYTNSIFGKAGI--PPAKIPYVTLSTGGIETLAAVFSGLVIEHLG 379
           +     QL G+  I  Y  SIF    +  PP     +    G +  L+ + + L ++  G
Sbjct: 281 LMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDDAAI---VGAVRLLSVLIAALTMDLAG 337

Query: 380 RRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLSIVGILAIIASFCSGPGGIPFILTG 439
           R+                                     +L  ++ +  G G I ++L  
Sbjct: 338 RK-------------------------------------VLLFVSGYAVGWGPITWLLMS 360

Query: 440 EFFQQSQRPAAFIIAGTVNWLSNFAVGLLF-PFIQKSLDTYCFLVFATICITGAIYLYFV 498
           E      R  A  +    +WL+ F +   F P +        F  FA IC+   ++    
Sbjct: 361 EVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCC 420

Query: 499 LPETKNRTYAEISQAFSKRNKAY 521
           +PETK R+  +I   F    +++
Sbjct: 421 VPETKGRSLEQIESFFRTGRRSF 443


>gi|203098995 solute carrier family 2 (facilitated glucose
           transporter), member 13 [Homo sapiens]
          Length = 648

 Score =  115 bits (287), Expect = 1e-25
 Identities = 96/339 (28%), Positives = 159/339 (46%), Gaps = 35/339 (10%)

Query: 58  VASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTL--TLLWSVTVS 115
           V ++  A G  FL+GY+  VV+     +K            R +  D L   LL S TV 
Sbjct: 83  VVAVFSALGG-FLFGYDTGVVSGAMLLLK------------RQLSLDALWQELLVSSTVG 129

Query: 116 IFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMG 175
             A+  L G  +  + G+   R   LLA+  F   +A+L A + +    E L+ GR ++G
Sbjct: 130 AAAVSALAGGALNGVFGR---RAAILLASALFTAGSAVLAAANNK----ETLLAGRLVVG 182

Query: 176 IDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLL-GLPELLGKESTWPYL 234
           +  G+A   +P+Y++E+SP  +RG L  +  +FI  G F   ++ G    L K+  W Y+
Sbjct: 183 LGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDG-WRYM 241

Query: 235 FGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEV---LA 291
            G+  VPAV+Q     FLP+SPR+ L++K    +A +      G   + +E + +   + 
Sbjct: 242 LGLAAVPAVIQFFGFLFLPESPRW-LIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIE 300

Query: 292 ESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPA 351
           E   +       +  +L  P  R  ++         QL G+N I +Y+ +I   +G+   
Sbjct: 301 EEEKEVGSAGPVICRMLSYPPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDD 360

Query: 352 KIPY----VTLSTGGIETLAAVFSGLVIEHLGRRPLLIG 386
           ++      VT  T  I TL  V+   ++E +GRR L  G
Sbjct: 361 RLAIWLASVTAFTNFIFTLVGVW---LVEKVGRRKLTFG 396



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 1/106 (0%)

Query: 413 YLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFI 472
           + +++G++  +  F  G G +P+ +  E +    R      +  +NW+ N  V L F   
Sbjct: 507 WTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSSGINWIFNVLVSLTFLHT 566

Query: 473 QKSLDTY-CFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKR 517
            + L  Y  F ++A     G +++Y  LPETK +   EI   F  R
Sbjct: 567 AEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEIESLFDNR 612


>gi|21553331 solute carrier family 2 (facilitated glucose
           transporter), member 12 [Homo sapiens]
          Length = 617

 Score = 90.5 bits (223), Expect = 3e-18
 Identities = 79/360 (21%), Positives = 161/360 (44%), Gaps = 27/360 (7%)

Query: 46  GRRRKDWS--CSLLV-ASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPID 102
           G R   W+  C +    S   A  S  L GY L +++     IK     S   +      
Sbjct: 26  GSRHPPWARGCGMFTFLSSVTAAVSGLLVGYELGIISGALLQIKTLLALSCHEQE----- 80

Query: 103 PDTLTLLWSVTVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAG 162
                    + VS   IG L+ +L   ++    GR+  ++ ++      +L++  SL   
Sbjct: 81  ---------MVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSL--- 128

Query: 163 AFEMLIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLP 222
           ++ +LIVGR  +G+   ++     +Y++EI+P+  RG L  +  + I IG+ +  +    
Sbjct: 129 SYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYA 188

Query: 223 ELLGKESTWPYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADV 282
                   W Y+FG+++   V+Q +++ FLP SPR+L++ K  E  A K        +D 
Sbjct: 189 -FANVFHGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVM-KGQEGAASKVLGRLRALSDT 246

Query: 283 SQEVEEVLAESRVQRSIRLVSVLELLRA-PYVRWQVVTVIVTMACYQLCGLNAIWFYTNS 341
           ++E+  + +  + +      S  +L R+   +R +++  +  +   Q+ G   I FY ++
Sbjct: 247 TEELTVIKSSLKDEYQ---YSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYAST 303

Query: 342 IFGKAGIPPAK-IPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTI 400
           +    G    +     +   G ++ ++ + + L+++H+G +  L  G  +M     T+ I
Sbjct: 304 VLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVTMGI 363



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 29/115 (25%), Positives = 56/115 (48%), Gaps = 3/115 (2%)

Query: 406 DHAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAV 465
           D   ++ +LS+  +L  +A+F  G G +P+++  E F    R  A  +  ++NW  N  +
Sbjct: 455 DVPAFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLI 514

Query: 466 GLLFPFIQK--SLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRN 518
            L F  +     L   CF ++  + +   +++   +PETK  +  +IS   +K N
Sbjct: 515 SLTFLTVTDLIGLPWVCF-IYTIMSLASLLFVVMFIPETKGCSLEQISMELAKVN 568


>gi|13540547 solute carrier family 2 member 10 [Homo sapiens]
          Length = 541

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 72/284 (25%), Positives = 120/284 (42%), Gaps = 30/284 (10%)

Query: 117 FAIGGLV-GTLIVKMIGKVL----GRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGR 171
           F +G L+ G L+  ++G  L    GRK  +L +N   ++ +L +     AG+   L++GR
Sbjct: 49  FLVGSLLLGALLASLVGGFLIDCYGRKQAILGSNLVLLAGSLTLGL---AGSLAWLVLGR 105

Query: 172 FIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTW 231
            ++G    ++     +Y+SE+     RG L  +    I +G+     L    L G    W
Sbjct: 106 AVVGFAISLSSMACCIYVSELVGPRQRGVLVSLYEAGITVGILLSYALNYA-LAGTPWGW 164

Query: 232 PYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLA 291
            ++FG    PAV+Q LSL FLP           +E    K      G           L 
Sbjct: 165 RHMFGWATAPAVLQSLSLLFLPAGT--------DETATHKDLIPLQGGE------APKLG 210

Query: 292 ESRVQRSIRLVSVLELLRA-PYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGI-P 349
             R +      S L+L RA   +R +    +  +   QL G   +  Y ++IF   G   
Sbjct: 211 PGRPR-----YSFLDLFRARDNMRGRTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGFHG 265

Query: 350 PAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGL 393
            +     ++  G ++  A + +  +++  GRR LL+ G  LM L
Sbjct: 266 GSSAVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALMAL 309



 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 27/106 (25%), Positives = 57/106 (53%), Gaps = 1/106 (0%)

Query: 413 YLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFI 472
           + +++ ++  +++F  G G + +++  E +    R  AF    + NW +N  + L F  +
Sbjct: 410 WTALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDL 469

Query: 473 QKSLD-TYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKR 517
             ++  ++ FL++    + G  ++Y  +PETK ++ AEI Q F KR
Sbjct: 470 IGTIGLSWTFLLYGLTAVLGLGFIYLFVPETKGQSLAEIDQQFQKR 515


>gi|90669191 solute carrier family 22 member 7 isoform b [Homo
           sapiens]
          Length = 548

 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 96/415 (23%), Positives = 163/415 (39%), Gaps = 43/415 (10%)

Query: 115 SIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIM 174
           + F  G LVG +    +    GR+  LL      +S  +L   S  + ++ M  + R + 
Sbjct: 149 TFFFAGVLVGAVAFGYLSDRFGRRRLLLVAY---VSTLVLGLASAASVSYVMFAITRTLT 205

Query: 175 GID-GGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPY 233
           G    G  + V+P+ L  +   E R   G +++ F   GV    LL L   L ++  W +
Sbjct: 206 GSALAGFTIIVMPLELEWLDV-EHRTVAGVLSSTFWTGGVM---LLALVGYLIRD--WRW 259

Query: 234 LFGVIVVPAVVQLLSLPFLPDSPRYLLLEKH-NEARAVKAFQTFLGKADVSQEVEEVLAE 292
           L   + +P    +LSL ++P+S R+LL + H  EA         L    V ++     A 
Sbjct: 260 LLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAV 319

Query: 293 SRV---QRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIP 349
           S+V   +R +R  S L+L R P +R       +++ C        +WF  N  +    + 
Sbjct: 320 SKVAAGERVVRRPSYLDLFRTPRLRH------ISLCCV------VVWFGVNFSYYGLSLD 367

Query: 350 PA----KIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQ 405
            +     +    L  G +E  + +   L + + GRR    G      L FGT    L   
Sbjct: 368 VSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTR--LLVSS 425

Query: 406 DHAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAV 465
           D   W   L+++G     A+F +      ++ T E +    R     +   V  L     
Sbjct: 426 DMKSWSTVLAVMGKAFSEAAFTTA-----YLFTSELYPTVLRQTGMGLTALVGRLGGSLA 480

Query: 466 GL--LFPFIQKSLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRN 518
            L  L   +  SL    +   A +    A+    +LPET+     E  Q   +++
Sbjct: 481 PLAALLDGVWLSLPKLTYGGIALLAAGTAL----LLPETRQAQLPETIQDVERKS 531


>gi|24497497 solute carrier family 22 member 7 isoform a [Homo
           sapiens]
          Length = 546

 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 96/415 (23%), Positives = 163/415 (39%), Gaps = 43/415 (10%)

Query: 115 SIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIM 174
           + F  G LVG +    +    GR+  LL      +S  +L   S  + ++ M  + R + 
Sbjct: 147 TFFFAGVLVGAVAFGYLSDRFGRRRLLLVAY---VSTLVLGLASAASVSYVMFAITRTLT 203

Query: 175 GID-GGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPY 233
           G    G  + V+P+ L  +   E R   G +++ F   GV    LL L   L ++  W +
Sbjct: 204 GSALAGFTIIVMPLELEWLDV-EHRTVAGVLSSTFWTGGVM---LLALVGYLIRD--WRW 257

Query: 234 LFGVIVVPAVVQLLSLPFLPDSPRYLLLEKH-NEARAVKAFQTFLGKADVSQEVEEVLAE 292
           L   + +P    +LSL ++P+S R+LL + H  EA         L    V ++     A 
Sbjct: 258 LLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAV 317

Query: 293 SRV---QRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIP 349
           S+V   +R +R  S L+L R P +R       +++ C        +WF  N  +    + 
Sbjct: 318 SKVAAGERVVRRPSYLDLFRTPRLRH------ISLCCV------VVWFGVNFSYYGLSLD 365

Query: 350 PA----KIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQ 405
            +     +    L  G +E  + +   L + + GRR    G      L FGT    L   
Sbjct: 366 VSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTR--LLVSS 423

Query: 406 DHAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAV 465
           D   W   L+++G     A+F +      ++ T E +    R     +   V  L     
Sbjct: 424 DMKSWSTVLAVMGKAFSEAAFTTA-----YLFTSELYPTVLRQTGMGLTALVGRLGGSLA 478

Query: 466 GL--LFPFIQKSLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRN 518
            L  L   +  SL    +   A +    A+    +LPET+     E  Q   +++
Sbjct: 479 PLAALLDGVWLSLPKLTYGGIALLAAGTAL----LLPETRQAQLPETIQDVERKS 529


>gi|24497476 solute carrier family 22 member 6 isoform b [Homo
           sapiens]
          Length = 550

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 109/526 (20%), Positives = 199/526 (37%), Gaps = 78/526 (14%)

Query: 21  TSHAGPPGPGRALLECDHLRSGVPGGRRRKDWSCSLLVASLAGAFGSSFLYGYNLSVVNA 80
           T H  PP     L +   L   +P  R+ +  SC    +     +G  FL G   +   A
Sbjct: 46  THHCRPPADAN-LSKNGGLEVWLPRDRQGQPESCLRFTSP---QWGLPFLNGTEANGTGA 101

Query: 81  PTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVS----------IFAIGGLVGTLIVKM 130
             P       + W   +     P T+   W +  S          ++ +G L+G ++   
Sbjct: 102 TEPC-----TDGWI--YDNSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGY 154

Query: 131 IGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGID-GGVALSVLPMYL 189
           +   LGR+  L+ N    +  A+   C+  A  F +    R + G+   G++L+ + + +
Sbjct: 155 LADRLGRRKVLILN---YLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNV 211

Query: 190 SEISPKEIRGSLGQVTAIFICIGVF--TGQLLGLPELLGKESTWPYLFGVIVVPAVVQLL 247
            E  P   R  +G +      +G F   G    +P        W +L  ++  P     +
Sbjct: 212 -EWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPH-------WRHLQLLVSAPFFAFFI 263

Query: 248 SLPFLPDSPRYLLLEKHNE--ARAVKAFQTFLGKADVSQEVEEVLAESRVQRSIRL---- 301
              F  +S R+       +   RA++      GK +   ++   +  + +Q+ + +    
Sbjct: 264 YSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQ 323

Query: 302 VSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIP------PAKIPY 355
            S +ELLR P           T+    LC L+ +WF T+  F   G+          I  
Sbjct: 324 ASAMELLRCP-----------TLRHLFLC-LSMLWFATS--FAYYGLVMDLQGFGVSIYL 369

Query: 356 VTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLS 415
           + +  G ++  A +   LVI  LGRRP  +    L G+    L   +  QD +     L+
Sbjct: 370 IQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICI--LLNGVIPQDQSIVRTSLA 427

Query: 416 IVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKS 475
           ++G   + ASF        F+ TGE +    R     +  T+  + +    ++ P +  +
Sbjct: 428 VLGKGCLAASF-----NCIFLYTGELYPTMIRQTGMGMGSTMARVGS----IVSPLVSMT 478

Query: 476 LDTY----CFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKR 517
            + Y     F+  A      A+ +  +LPET  +   +  Q    R
Sbjct: 479 AELYPSMPLFIYGAVPVAASAVTV--LLPETLGQPLPDTVQDLESR 522


>gi|20070188 solute carrier family 22 member 6 isoform a [Homo
           sapiens]
          Length = 563

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 109/526 (20%), Positives = 199/526 (37%), Gaps = 78/526 (14%)

Query: 21  TSHAGPPGPGRALLECDHLRSGVPGGRRRKDWSCSLLVASLAGAFGSSFLYGYNLSVVNA 80
           T H  PP     L +   L   +P  R+ +  SC    +     +G  FL G   +   A
Sbjct: 46  THHCRPPADAN-LSKNGGLEVWLPRDRQGQPESCLRFTSP---QWGLPFLNGTEANGTGA 101

Query: 81  PTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVS----------IFAIGGLVGTLIVKM 130
             P       + W   +     P T+   W +  S          ++ +G L+G ++   
Sbjct: 102 TEPC-----TDGWI--YDNSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGY 154

Query: 131 IGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGID-GGVALSVLPMYL 189
           +   LGR+  L+ N    +  A+   C+  A  F +    R + G+   G++L+ + + +
Sbjct: 155 LADRLGRRKVLILN---YLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNV 211

Query: 190 SEISPKEIRGSLGQVTAIFICIGVF--TGQLLGLPELLGKESTWPYLFGVIVVPAVVQLL 247
            E  P   R  +G +      +G F   G    +P        W +L  ++  P     +
Sbjct: 212 -EWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPH-------WRHLQLLVSAPFFAFFI 263

Query: 248 SLPFLPDSPRYLLLEKHNE--ARAVKAFQTFLGKADVSQEVEEVLAESRVQRSIRL---- 301
              F  +S R+       +   RA++      GK +   ++   +  + +Q+ + +    
Sbjct: 264 YSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQ 323

Query: 302 VSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIP------PAKIPY 355
            S +ELLR P           T+    LC L+ +WF T+  F   G+          I  
Sbjct: 324 ASAMELLRCP-----------TLRHLFLC-LSMLWFATS--FAYYGLVMDLQGFGVSIYL 369

Query: 356 VTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLS 415
           + +  G ++  A +   LVI  LGRRP  +    L G+    L   +  QD +     L+
Sbjct: 370 IQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICI--LLNGVIPQDQSIVRTSLA 427

Query: 416 IVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKS 475
           ++G   + ASF        F+ TGE +    R     +  T+  + +    ++ P +  +
Sbjct: 428 VLGKGCLAASF-----NCIFLYTGELYPTMIRQTGMGMGSTMARVGS----IVSPLVSMT 478

Query: 476 LDTY----CFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKR 517
            + Y     F+  A      A+ +  +LPET  +   +  Q    R
Sbjct: 479 AELYPSMPLFIYGAVPVAASAVTV--LLPETLGQPLPDTVQDLESR 522


>gi|24497480 solute carrier family 22 member 6 isoform d [Homo
           sapiens]
          Length = 519

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 98/462 (21%), Positives = 176/462 (38%), Gaps = 68/462 (14%)

Query: 21  TSHAGPPGPGRALLECDHLRSGVPGGRRRKDWSCSLLVASLAGAFGSSFLYGYNLSVVNA 80
           T H  PP     L +   L   +P  R+ +  SC    +     +G  FL G   +   A
Sbjct: 46  THHCRPPADAN-LSKNGGLEVWLPRDRQGQPESCLRFTSP---QWGLPFLNGTEANGTGA 101

Query: 81  PTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVS----------IFAIGGLVGTLIVKM 130
             P       + W   +     P T+   W +  S          ++ +G L+G ++   
Sbjct: 102 TEPC-----TDGWI--YDNSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGY 154

Query: 131 IGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGID-GGVALSVLPMYL 189
           +   LGR+  L+ N    +  A+   C+  A  F +    R + G+   G++L+ + + +
Sbjct: 155 LADRLGRRKVLILN---YLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNV 211

Query: 190 SEISPKEIRGSLGQVTAIFICIGVF--TGQLLGLPELLGKESTWPYLFGVIVVPAVVQLL 247
            E  P   R  +G +      +G F   G    +P        W +L  ++  P     +
Sbjct: 212 -EWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPH-------WRHLQLLVSAPFFAFFI 263

Query: 248 SLPFLPDSPRYLLLEKHNE--ARAVKAFQTFLGKADVSQEVEEVLAESRVQRSIRL---- 301
              F  +S R+       +   RA++      GK +   ++   +  + +Q+ + +    
Sbjct: 264 YSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQ 323

Query: 302 VSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIP------PAKIPY 355
            S +ELLR P           T+    LC L+ +WF T+  F   G+          I  
Sbjct: 324 ASAMELLRCP-----------TLRHLFLC-LSMLWFATS--FAYYGLVMDLQGFGVSIYL 369

Query: 356 VTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLS 415
           + +  G ++  A +   LVI  LGRRP  +    L G+    L   +  QD +     L+
Sbjct: 370 IQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICI--LLNGVIPQDQSIVRTSLA 427

Query: 416 IVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTV 457
           ++G   + ASF        F+ TGE +    R    ++  T+
Sbjct: 428 VLGKGCLAASF-----NCIFLYTGELYPTMIRAVTVLLPETL 464


>gi|24497478 solute carrier family 22 member 6 isoform c [Homo
           sapiens]
          Length = 506

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 98/462 (21%), Positives = 176/462 (38%), Gaps = 68/462 (14%)

Query: 21  TSHAGPPGPGRALLECDHLRSGVPGGRRRKDWSCSLLVASLAGAFGSSFLYGYNLSVVNA 80
           T H  PP     L +   L   +P  R+ +  SC    +     +G  FL G   +   A
Sbjct: 46  THHCRPPADAN-LSKNGGLEVWLPRDRQGQPESCLRFTSP---QWGLPFLNGTEANGTGA 101

Query: 81  PTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVS----------IFAIGGLVGTLIVKM 130
             P       + W   +     P T+   W +  S          ++ +G L+G ++   
Sbjct: 102 TEPC-----TDGWI--YDNSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGY 154

Query: 131 IGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGID-GGVALSVLPMYL 189
           +   LGR+  L+ N    +  A+   C+  A  F +    R + G+   G++L+ + + +
Sbjct: 155 LADRLGRRKVLILN---YLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNV 211

Query: 190 SEISPKEIRGSLGQVTAIFICIGVF--TGQLLGLPELLGKESTWPYLFGVIVVPAVVQLL 247
            E  P   R  +G +      +G F   G    +P        W +L  ++  P     +
Sbjct: 212 -EWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPH-------WRHLQLLVSAPFFAFFI 263

Query: 248 SLPFLPDSPRYLLLEKHNE--ARAVKAFQTFLGKADVSQEVEEVLAESRVQRSIRL---- 301
              F  +S R+       +   RA++      GK +   ++   +  + +Q+ + +    
Sbjct: 264 YSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQ 323

Query: 302 VSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIP------PAKIPY 355
            S +ELLR P           T+    LC L+ +WF T+  F   G+          I  
Sbjct: 324 ASAMELLRCP-----------TLRHLFLC-LSMLWFATS--FAYYGLVMDLQGFGVSIYL 369

Query: 356 VTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPWVPYLS 415
           + +  G ++  A +   LVI  LGRRP  +    L G+    L   +  QD +     L+
Sbjct: 370 IQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICI--LLNGVIPQDQSIVRTSLA 427

Query: 416 IVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTV 457
           ++G   + ASF        F+ TGE +    R    ++  T+
Sbjct: 428 VLGKGCLAASF-----NCIFLYTGELYPTMIRAVTVLLPETL 464


>gi|213021148 SVOP-like isoform 1 [Homo sapiens]
          Length = 492

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 94/429 (21%), Positives = 175/429 (40%), Gaps = 56/429 (13%)

Query: 112 VTVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALL--MACSLQAGAFEMLIV 169
           VT  +F  G +V +++  ++    GR   LL +  +    +LL   A S     F   +V
Sbjct: 89  VTTMVF-FGYMVFSILFGLLADRYGRWKILLISFLWGAYFSLLTSFAPSYIWFVFLRTMV 147

Query: 170 GRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKES 229
           G  + G   G+ +       +E  P + RG +  ++ +F   G     ++GL  ++    
Sbjct: 148 GCGVSGHSQGLIIK------TEFLPTKYRGYMLPLSQVFWLAGSLL--IIGLASVIIPTI 199

Query: 230 TWPYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEV 289
            W +L  V  +P ++ +++  F+P+S R+ +       RA  A    + K + S   E  
Sbjct: 200 GWRWLIRVASIPGIILIVAFKFIPESARFNV--STGNTRAALATLERVAKMNRSVMPEGK 257

Query: 290 LAESRVQRSIRLVSVLE--LLRAPYVRWQVVTVIVTMACY-------------QLCG--L 332
           L E  +++  R   +L+   LR     W V+ + ++ A Y              +CG   
Sbjct: 258 LVEPVLEKRGRFADLLDAKYLRTTLQIW-VIWLGISFAYYGVILASAELLERDLVCGSKS 316

Query: 333 NAIWFYTNSIFGKAGIP-------PAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLI 385
           ++    T    G++  P       P+    + +ST G E      + L I  LGRR  L 
Sbjct: 317 DSAVVVTGGDSGESQSPCYCHMFAPSDYRTMIISTIG-EIALNPLNILGINFLGRRLSLS 375

Query: 386 GGFGLMGLFFGTLTITLTLQDHAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQS 445
              G   LFF  L I  +            ++G L ++ +  +      +I T E +  +
Sbjct: 376 ITMGCTALFFLLLNICTS---------SAGLIGFLFMLRALVAANFNTVYIYTAEVYPTT 426

Query: 446 QRPAAFIIAGTVNWLSNFAVGLLFPFIQKSLDTYCFL----VFATICITGAIYLYFVLPE 501
            R      +G++  +      ++ PFI + L +   L    +F+++C+  AI  + +  E
Sbjct: 427 MRALGMGTSGSLCRIG----AMVAPFISQVLMSASILGALCLFSSVCVVCAISAFTLPIE 482

Query: 502 TKNRTYAEI 510
           TK R   +I
Sbjct: 483 TKGRALQQI 491


>gi|7662270 synaptic vesicle protein 2B homolog [Homo sapiens]
          Length = 683

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 49/164 (29%), Positives = 72/164 (43%), Gaps = 15/164 (9%)

Query: 116 IFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMG 175
           I  +G + G  I+  +   LGRK  L  +     S A L +     GAF   +  R I G
Sbjct: 153 IVYLGMMAGAFILGGLADKLGRKRVLSMSLAVNASFASLSSFVQGYGAF---LFCRLISG 209

Query: 176 IDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLG---LPEL-----LGK 227
           I  G AL ++  Y SE   +E RG       IF   G      +    +P       +G 
Sbjct: 210 IGIGGALPIVFAYFSEFLSREKRGEHLSWLGIFWMTGGLYASAMAWSIIPHYGWGFSMGT 269

Query: 228 E---STWPYLFGVIVVPAVVQLLSLPFLPDSPRYLL-LEKHNEA 267
                +W     V  +P  V +++L F+P+SPR+LL + KH+EA
Sbjct: 270 NYHFHSWRVFVIVCALPCTVSMVALKFMPESPRFLLEMGKHDEA 313


>gi|33457322 SVOP-like isoform 2 [Homo sapiens]
          Length = 340

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 76/349 (21%), Positives = 143/349 (40%), Gaps = 47/349 (13%)

Query: 190 SEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGVIVVPAVVQLLSL 249
           +E  P + RG +  ++ +F   G     ++GL  ++     W +L  V  +P ++ +++ 
Sbjct: 10  TEFLPTKYRGYMLPLSQVFWLAGSLL--IIGLASVIIPTIGWRWLIRVASIPGIILIVAF 67

Query: 250 PFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQRSIRLVSVLE--L 307
            F+P+S R+ +       RA  A    + K + S   E  L E  +++  R   +L+   
Sbjct: 68  KFIPESARFNV--STGNTRAALATLERVAKMNRSVMPEGKLVEPVLEKRGRFADLLDAKY 125

Query: 308 LRAPYVRWQVVTVIVTMACY-------------QLCG--LNAIWFYTNSIFGKAGIP--- 349
           LR     W V+ + ++ A Y              +CG   ++    T    G++  P   
Sbjct: 126 LRTTLQIW-VIWLGISFAYYGVILASAELLERDLVCGSKSDSAVVVTGGDSGESQSPCYC 184

Query: 350 ----PAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQ 405
               P+    + +ST G E      + L I  LGRR  L    G   LFF  L I  +  
Sbjct: 185 HMFAPSDYRTMIISTIG-EIALNPLNILGINFLGRRLSLSITMGCTALFFLLLNICTS-- 241

Query: 406 DHAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAV 465
                     ++G L ++ +  +      +I T E +  + R      +G++  +     
Sbjct: 242 -------SAGLIGFLFMLRALVAANFNTVYIYTAEVYPTTMRALGMGTSGSLCRIG---- 290

Query: 466 GLLFPFIQKSLDTYCFL----VFATICITGAIYLYFVLPETKNRTYAEI 510
            ++ PFI + L +   L    +F+++C+  AI  + +  ETK R   +I
Sbjct: 291 AMVAPFISQVLMSASILGALCLFSSVCVVCAISAFTLPIETKGRALQQI 339


>gi|11415038 solute carrier family 22 member 3 [Homo sapiens]
          Length = 556

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 92/403 (22%), Positives = 164/403 (40%), Gaps = 48/403 (11%)

Query: 112 VTVSIFAIGGLVGTLIVKMIGKVLGRKHT-LLANNGFAISAALLMACSLQAGAFEMLIVG 170
           +T +I  +G L G   +       GR    LL+  G  ++  ++      A  F + ++ 
Sbjct: 156 LTQAILNLGFLTGAFTLGYAADRYGRIVIYLLSCLGVGVTGVVVAF----APNFPVFVIF 211

Query: 171 RFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKEST 230
           RF+ G+ G        + ++EI   + R  +G V  +F  +G+       LP +      
Sbjct: 212 RFLQGVFGKGTWMTCYVIVTEIVGSKQRRIVGIVIQMFFTLGIII-----LPGIAYFIPN 266

Query: 231 WPYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNE--ARAVKAFQTFLGKADVSQEVEE 288
           W  +   I +P+ + LL    +P+SPR+L+  K  +   + ++      GK   S   E 
Sbjct: 267 WQGIQLAITLPSFLFLLYYWVVPESPRWLITRKKGDKALQILRRIAKCNGKYLSSNYSEI 326

Query: 289 VLAESRVQRSIRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFG---- 344
            + +  V       S L+L+R P +R    T+I+  A          WF +  ++     
Sbjct: 327 TVTDEEVSNP----SFLDLVRTPQMR--KCTLILMFA----------WFTSAVVYQGLVM 370

Query: 345 KAGIPPAKIPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTL 404
           + GI    +      +G +E   A+   L IE LGRR        + G+      +T  L
Sbjct: 371 RLGIIGGNLYIDFFISGVVELPGALLILLTIERLGRRLPFAASNIVAGV---ACLVTAFL 427

Query: 405 QDHAPWV-PYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRP-AAFIIAGTVNWLSN 462
            +   W+   ++ +G L I  +F      I +++  E +  + R     + +G  ++   
Sbjct: 428 PEGIAWLRTTVATLGRLGITMAF-----EIVYLVNSELYPTTLRNFGVSLCSGLCDFGGI 482

Query: 463 FAVGLLFPF--IQKSLDTYCFLVFATICITGAIYLYFVLPETK 503
            A  LLF    +   L    F + A+IC  G   L  +LPETK
Sbjct: 483 IAPFLLFRLAAVWLELPLIIFGILASIC--GG--LVMLLPETK 521


>gi|239751156 PREDICTED: hypothetical protein LOC146429 isoform 6
           [Homo sapiens]
          Length = 560

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 116/448 (25%), Positives = 182/448 (40%), Gaps = 56/448 (12%)

Query: 83  PYIKAFYNESWERRHGRPIDPDTLTLL----WSVTVSIFA--IGGLVGTLIVKMIGKVLG 136
           P  +A    SW    G    P T  L+    W V +   +  +G L+G +I+       G
Sbjct: 99  PLTRAPRPSSWASCSGAAAGP-TWNLVCGDGWKVPLEQVSHLLGWLLGCVILGAGCDRFG 157

Query: 137 RKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGIDGGVALSVLPMYLSEIS--- 193
           R+   +A+    +    L A    A +F  L+V R + G  G +A ++L +YL+ +    
Sbjct: 158 RRAVFVAS---LVLTTGLGASEALAASFPTLLVLRLLHG--GTLAGALLALYLARLELCD 212

Query: 194 -PKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGVIVVPAVVQLLSLPF- 251
            P  +  S+G    +F  +G      L LP L      W  L G+  + + + LL   F 
Sbjct: 213 PPHRLAFSMG--AGLFSVVGT-----LLLPGLAALVQDWRLLQGLGALMSGLLLLFWGFP 265

Query: 252 --LPDSPRYLLLEKHNEARAVKAFQTF-----LGKADVSQE------VEEVLAESRVQRS 298
              P+SP +LL      ARA K    F     +G  D S E        E+   S     
Sbjct: 266 ALFPESPCWLLATGQ-VARARKILWRFAEASGVGPGDSSLEENSLATATELTMLSARSPQ 324

Query: 299 IRLVSVLELLRAPYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAKIPYVTL 358
            R  S L LLR   V W+   ++       L G      +  S+  +  +P   +PY   
Sbjct: 325 PRYHSPLGLLRTR-VTWRNGLIL---GFSSLVGGGIRASFRRSLAPQ--VPTFYLPYFL- 377

Query: 359 STGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTITLTLQDHAPW-VPYLSIV 417
              G+E  A VF  L  +  GRRP+L+ G  + GL   +L +    Q    W V +LS++
Sbjct: 378 -EAGLEAAALVFLLLTADCCGRRPVLLLGTMVTGL--ASLLLLAGAQYLPGWTVLFLSVL 434

Query: 418 GILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAVGLLFPFIQKSLD 477
           G+LA  A        +  +   E F    R A   +     +L   A GLL     +   
Sbjct: 435 GLLASRA-----VSALSSLFAAEVFPTVIRGAGLGLVLGAGFLGQ-AAGLLDTLHGRQGF 488

Query: 478 TYCFLVFATICITGAIYLYFVLPETKNR 505
               +VFA++ +  A+    +LPE+++R
Sbjct: 489 FLQQVVFASLAVL-ALLCVLLLPESRSR 515


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.141    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,682,191
Number of Sequences: 37866
Number of extensions: 929847
Number of successful extensions: 2666
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 2572
Number of HSP's gapped (non-prelim): 85
length of query: 540
length of database: 18,247,518
effective HSP length: 107
effective length of query: 433
effective length of database: 14,195,856
effective search space: 6146805648
effective search space used: 6146805648
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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