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Search of human proteins with 47778943
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|47778943 syntaxin 16 isoform a [Homo sapiens]
(325 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|47778943 syntaxin 16 isoform a [Homo sapiens] 629 0.0
gi|198041688 syntaxin 16 isoform c [Homo sapiens] 616 e-176
gi|198041692 syntaxin 16 isoform d [Homo sapiens] 587 e-168
gi|34447229 syntaxin 16 isoform b [Homo sapiens] 578 e-165
gi|170932494 syntaxin 7 [Homo sapiens] 93 3e-19
gi|28933465 syntaxin 12 [Homo sapiens] 93 3e-19
gi|4759182 syntaxin 1A (brain) [Homo sapiens] 85 8e-17
gi|16418379 syntaxin 1B [Homo sapiens] 81 1e-15
gi|4759184 syntaxin 3 [Homo sapiens] 80 3e-15
gi|37577287 syntaxin 2 isoform 1 [Homo sapiens] 71 1e-12
gi|37577162 syntaxin 2 isoform 2 [Homo sapiens] 69 4e-12
gi|20149560 syntaxin 4 [Homo sapiens] 69 6e-12
gi|94400932 syntaxin 5 [Homo sapiens] 60 3e-09
gi|223972648 t-SNARE domain containing 1 [Homo sapiens] 52 6e-07
gi|33667038 syntaxin 11 [Homo sapiens] 48 1e-05
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 42 6e-04
gi|49258196 syntaxin 19 [Homo sapiens] 41 0.002
gi|4507285 syntaxin 10 [Homo sapiens] 38 0.011
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo... 38 0.014
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof... 38 0.014
gi|4504063 golgin 97 [Homo sapiens] 38 0.014
gi|110611218 ribosome binding protein 1 [Homo sapiens] 37 0.031
gi|110611220 ribosome binding protein 1 [Homo sapiens] 37 0.031
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap... 37 0.031
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap... 37 0.031
gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sap... 37 0.031
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 36 0.041
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 36 0.041
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 36 0.041
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 36 0.041
>gi|47778943 syntaxin 16 isoform a [Homo sapiens]
Length = 325
Score = 629 bits (1623), Expect = 0.0
Identities = 325/325 (100%), Positives = 325/325 (100%)
Query: 1 MATRRLTDAFLLLRNNSIQNRQLLAEQVSSHITSSPLHSRSIAAELDELADDRMALVSGI 60
MATRRLTDAFLLLRNNSIQNRQLLAEQVSSHITSSPLHSRSIAAELDELADDRMALVSGI
Sbjct: 1 MATRRLTDAFLLLRNNSIQNRQLLAEQVSSHITSSPLHSRSIAAELDELADDRMALVSGI 60
Query: 61 SLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEH 120
SLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEH
Sbjct: 61 SLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEH 120
Query: 121 AIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQ 180
AIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQ
Sbjct: 121 AIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQ 180
Query: 181 SGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREI 240
SGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREI
Sbjct: 181 SGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREI 240
Query: 241 RQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNR 300
RQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNR
Sbjct: 241 RQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNR 300
Query: 301 KMLVILILFVIIIVLIVVLVGVKSR 325
KMLVILILFVIIIVLIVVLVGVKSR
Sbjct: 301 KMLVILILFVIIIVLIVVLVGVKSR 325
>gi|198041688 syntaxin 16 isoform c [Homo sapiens]
Length = 321
Score = 616 bits (1588), Expect = e-176
Identities = 321/325 (98%), Positives = 321/325 (98%), Gaps = 4/325 (1%)
Query: 1 MATRRLTDAFLLLRNNSIQNRQLLAEQVSSHITSSPLHSRSIAAELDELADDRMALVSGI 60
MATRRLTDAFLLLRNNSIQNRQLLAEQVSSHITSSPLHSRSIAA LADDRMALVSGI
Sbjct: 1 MATRRLTDAFLLLRNNSIQNRQLLAEQVSSHITSSPLHSRSIAA----LADDRMALVSGI 56
Query: 61 SLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEH 120
SLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEH
Sbjct: 57 SLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEH 116
Query: 121 AIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQ 180
AIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQ
Sbjct: 117 AIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQ 176
Query: 181 SGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREI 240
SGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREI
Sbjct: 177 SGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREI 236
Query: 241 RQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNR 300
RQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNR
Sbjct: 237 RQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNR 296
Query: 301 KMLVILILFVIIIVLIVVLVGVKSR 325
KMLVILILFVIIIVLIVVLVGVKSR
Sbjct: 297 KMLVILILFVIIIVLIVVLVGVKSR 321
>gi|198041692 syntaxin 16 isoform d [Homo sapiens]
Length = 308
Score = 587 bits (1514), Expect = e-168
Identities = 308/325 (94%), Positives = 308/325 (94%), Gaps = 17/325 (5%)
Query: 1 MATRRLTDAFLLLRNNSIQNRQLLAEQVSSHITSSPLHSRSIAAELDELADDRMALVSGI 60
MATRRLTDAFLLLRNNSIQNRQLLAEQ ELDELADDRMALVSGI
Sbjct: 1 MATRRLTDAFLLLRNNSIQNRQLLAEQ-----------------ELDELADDRMALVSGI 43
Query: 61 SLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEH 120
SLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEH
Sbjct: 44 SLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEH 103
Query: 121 AIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQ 180
AIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQ
Sbjct: 104 AIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQ 163
Query: 181 SGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREI 240
SGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREI
Sbjct: 164 SGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREI 223
Query: 241 RQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNR 300
RQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNR
Sbjct: 224 RQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNR 283
Query: 301 KMLVILILFVIIIVLIVVLVGVKSR 325
KMLVILILFVIIIVLIVVLVGVKSR
Sbjct: 284 KMLVILILFVIIIVLIVVLVGVKSR 308
>gi|34447229 syntaxin 16 isoform b [Homo sapiens]
Length = 304
Score = 578 bits (1490), Expect = e-165
Identities = 304/325 (93%), Positives = 304/325 (93%), Gaps = 21/325 (6%)
Query: 1 MATRRLTDAFLLLRNNSIQNRQLLAEQVSSHITSSPLHSRSIAAELDELADDRMALVSGI 60
MATRRLTDAFLLLRNNSIQNRQLLAEQ LADDRMALVSGI
Sbjct: 1 MATRRLTDAFLLLRNNSIQNRQLLAEQ---------------------LADDRMALVSGI 39
Query: 61 SLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEH 120
SLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEH
Sbjct: 40 SLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEH 99
Query: 121 AIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQ 180
AIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQ
Sbjct: 100 AIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQ 159
Query: 181 SGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREI 240
SGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREI
Sbjct: 160 SGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREI 219
Query: 241 RQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNR 300
RQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNR
Sbjct: 220 RQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNR 279
Query: 301 KMLVILILFVIIIVLIVVLVGVKSR 325
KMLVILILFVIIIVLIVVLVGVKSR
Sbjct: 280 KMLVILILFVIIIVLIVVLVGVKSR 304
>gi|170932494 syntaxin 7 [Homo sapiens]
Length = 261
Score = 93.2 bits (230), Expect = 3e-19
Identities = 73/237 (30%), Positives = 115/237 (48%), Gaps = 14/237 (5%)
Query: 94 QKMKELASLHDKHLNR-PTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRARACSE 152
QK+ + + + LN+ T DS E ++ Q QL + ++ S SE
Sbjct: 23 QKITQCSVEIQRTLNQLGTPQDSPELRQQLQQKQQYTNQLAKETDKYIKEFGSLPTTPSE 82
Query: 153 QEGRLL--GNVVASLAQALQELSTSFRHAQSGYLKRMKN--REERSQHFFDTSVPLMDDG 208
Q R + +VA +L T+F+ Q +R K R+ S P
Sbjct: 83 QRQRKIQKDRLVAEFTTSL----TNFQKVQRQAAEREKEFVARVRASSRVSGSFPEDSSK 138
Query: 209 DDNTLYHRGFTEDQLV-----LVEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVE 263
+ N + T+ Q+ + E + ++ ERE IRQ+ I D+NEIF+DLG MI E
Sbjct: 139 ERNLVSWESQTQPQVQVQDEEITEDDLRLIHERESSIRQLEADIMDINEIFKDLGMMIHE 198
Query: 264 QGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIVVLV 320
QG V+D I+ NVE + + + +QL +A YQ+K+RK L I+IL ++I V I+ L+
Sbjct: 199 QGDVIDSIEANVENAEVHVQQANQQLSRAADYQRKSRKTLCIIILILVIGVAIISLI 255
>gi|28933465 syntaxin 12 [Homo sapiens]
Length = 276
Score = 93.2 bits (230), Expect = 3e-19
Identities = 75/256 (29%), Positives = 132/256 (51%), Gaps = 15/256 (5%)
Query: 76 PKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSS---EEEHAIEITTQEITQL 132
P+ D IQ G I++ + A + + T DSS E ++ +T ++ +
Sbjct: 17 PQLRDFSSIIQTCSGNIQRISQATAQIKNLMSQLGTKQDSSKLQENLQQLQHSTNQLAKE 76
Query: 133 FHRCQRAVQALP-----SRARACSEQEGRLLGNVVASLA--QALQELSTSFRHAQSGYLK 185
+ + + +LP S R Q+ RL+ + A+L QA+Q S + +S
Sbjct: 77 TNELLKELGSLPLPLSTSEQRQQRLQKERLMNDFSAALNNFQAVQR-RVSEKEKESIARA 135
Query: 186 RMKNREERSQHFFDTSVPLMDDGDD-NTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIV 244
R +R + + + D ++ N + + ED++ + EQ+ +++ERE IRQ+
Sbjct: 136 RAGSRLSAEERQREEQLVSFDSHEEWNQMQSQ---EDEVAITEQDLELIKERETAIRQLE 192
Query: 245 QSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLV 304
I D+N+IF+DL MI +QG ++D I+ NVE S + E +QL +A YQKK+RK +
Sbjct: 193 ADILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERATEQLQRAAYYQKKSRKKMC 252
Query: 305 ILILFVIIIVLIVVLV 320
IL+L + +I+LI+ L+
Sbjct: 253 ILVLVLSVIILILGLI 268
>gi|4759182 syntaxin 1A (brain) [Homo sapiens]
Length = 288
Score = 85.1 bits (209), Expect = 8e-17
Identities = 69/274 (25%), Positives = 138/274 (50%), Gaps = 21/274 (7%)
Query: 63 DPEAAIGVTK-RPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHA 121
D + A+ V + R ++ + V+EI+ + +I + ++E+ H L P D+ ++EE
Sbjct: 17 DDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEE-- 74
Query: 122 IEITTQEITQLFHRCQRAVQALPSRARACSEQEG--------RLLGNVVASLAQALQELS 173
+E +I + ++ + ++++ ++ ++EG R+ ++L++ E+
Sbjct: 75 LEELMSDIKKTANKVRSKLKSIE---QSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVM 131
Query: 174 TSFRHAQSGYLKRMKNREERSQHFFD---TSVPLMD--DGDDNTLYHRGFTEDQLVLVEQ 228
+ + QS Y +R K R +R TS L D + + ++ G D + +Q
Sbjct: 132 SEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSIS-KQ 190
Query: 229 NTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQ 288
+E R EI ++ SI +L+++F D+ ++ QG ++DRI+YNVE + E +
Sbjct: 191 ALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSD 250
Query: 289 LHKAEQYQKK-NRKMLVILILFVIIIVLIVVLVG 321
KA +YQ K RK ++I+I VI+ ++I VG
Sbjct: 251 TKKAVKYQSKARRKKIMIIICCVILGIVIASTVG 284
>gi|16418379 syntaxin 1B [Homo sapiens]
Length = 288
Score = 81.3 bits (199), Expect = 1e-15
Identities = 65/260 (25%), Positives = 133/260 (51%), Gaps = 22/260 (8%)
Query: 77 KWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRC 136
++ + V+EI+ + ++ + ++++ H L P D+ +++E +E T +I + ++
Sbjct: 31 EFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQE--LEDLTADIKKTANKV 88
Query: 137 QRAVQALPSRARACSEQEG--------RLLGNVVASLAQALQELSTSFRHAQSGYLKRMK 188
+ ++A+ ++ ++EG R+ ++L++ E+ T + QS Y R K
Sbjct: 89 RSKLKAIE---QSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCK 145
Query: 189 NREERSQHFFD---TSVPLMDDGDDNTLYHRGFTEDQLV---LVEQNTLMVEEREREIRQ 242
+R +R T+ L D + L FT+D + + +Q +E R EI +
Sbjct: 146 DRIQRQLEITGRTTTNEELEDMLESGKLAI--FTDDIKMDSQMTKQALNEIETRHNEIIK 203
Query: 243 IVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKK-NRK 301
+ SI +L+++F D+ ++ QG ++DRI+YNVE S E + KA +YQ K RK
Sbjct: 204 LETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRK 263
Query: 302 MLVILILFVIIIVLIVVLVG 321
++I+I V++ V++ +G
Sbjct: 264 KIMIIICCVVLGVVLASSIG 283
>gi|4759184 syntaxin 3 [Homo sapiens]
Length = 289
Score = 79.7 bits (195), Expect = 3e-15
Identities = 54/247 (21%), Positives = 124/247 (50%), Gaps = 12/247 (4%)
Query: 82 VDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQ 141
++E + ++ +I + ++E L+ L+ P + ++++ +E T EI + + + ++
Sbjct: 39 IEETRLNIDKISEHVEEAKKLYSIILSAPIPEPKTKDD--LEQLTTEIKKRANNVRNKLK 96
Query: 142 ALPSRAR---ACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFF 198
++ S + R+ + + L++ E+ T + AQ + +R K R +R
Sbjct: 97 SMEKHIEEDEVRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEIT 156
Query: 199 -----DTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEI 253
D + M + + ++ G + Q+ +Q +E R ++I ++ SI +L+++
Sbjct: 157 GKKTTDEELEEMLESGNPAIFTSGIIDSQIS--KQALSEIEGRHKDIVRLESSIKELHDM 214
Query: 254 FRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIII 313
F D+ ++ QG +LD I+ NV + E + KA +YQ + RK L+I+I+ V+++
Sbjct: 215 FMDIAMLVENQGEMLDNIELNVMHTVDHVEKARDETKKAVKYQSQARKKLIIIIVLVVVL 274
Query: 314 VLIVVLV 320
+ I+ L+
Sbjct: 275 LGILALI 281
>gi|37577287 syntaxin 2 isoform 1 [Homo sapiens]
Length = 287
Score = 70.9 bits (172), Expect = 1e-12
Identities = 54/250 (21%), Positives = 121/250 (48%), Gaps = 15/250 (6%)
Query: 82 VDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQ 141
V+EI+ + +I Q ++E+ H L+ P + +EE +E +EI + ++ + ++
Sbjct: 36 VEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEE--LEDLNKEIKKTANKIRAKLK 93
Query: 142 ALPS-----RARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQH 196
A+ + + + R+ + L++ E + AQ+ + +R K R +R
Sbjct: 94 AIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLE 153
Query: 197 FF------DTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDL 250
D +++ G + ++ Q+ N +E R ++I ++ SI +L
Sbjct: 154 ITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNE--IESRHKDIMKLETSIREL 211
Query: 251 NEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFV 310
+E+F D+ + QG +++ I+ NV + E ++ KA +YQ K R+ L+ +I+ V
Sbjct: 212 HEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKLMFIIICV 271
Query: 311 IIIVLIVVLV 320
I++++I+ ++
Sbjct: 272 IVLLVILGII 281
>gi|37577162 syntaxin 2 isoform 2 [Homo sapiens]
Length = 288
Score = 69.3 bits (168), Expect = 4e-12
Identities = 54/253 (21%), Positives = 121/253 (47%), Gaps = 16/253 (6%)
Query: 82 VDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQ 141
V+EI+ + +I Q ++E+ H L+ P + +EE +E +EI + ++ + ++
Sbjct: 36 VEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEE--LEDLNKEIKKTANKIRAKLK 93
Query: 142 AL-----PSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQH 196
A+ + + + R+ + L++ E + AQ+ + +R K R +R
Sbjct: 94 AIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLE 153
Query: 197 FF------DTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDL 250
D +++ G + ++ Q+ N +E R ++I ++ SI +L
Sbjct: 154 ITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNE--IESRHKDIMKLETSIREL 211
Query: 251 NEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKK-NRKMLVILILF 309
+E+F D+ + QG +++ I+ NV + E ++ KA +YQ K RK +I+ +
Sbjct: 212 HEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKKWIIIAVS 271
Query: 310 VIIIVLIVVLVGV 322
V+++ +I +++G+
Sbjct: 272 VVLVAIIALIIGL 284
>gi|20149560 syntaxin 4 [Homo sapiens]
Length = 297
Score = 68.9 bits (167), Expect = 6e-12
Identities = 65/261 (24%), Positives = 121/261 (46%), Gaps = 16/261 (6%)
Query: 74 PPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLF 133
P ++ V I+ + ++ K++EL L P ++S ++E ++ EI QL
Sbjct: 37 PDEEFFHKVRTIRQTIVKLGNKVQELEKQQVTILATPLPEESMKQE--LQNLRDEIKQLG 94
Query: 134 HRCQRAVQALPSRARACSEQEG----RLLGNVVASLAQALQELSTSFRHAQSGYLKRMKN 189
+ ++A+ + E R+ L+Q EL QS Y R KN
Sbjct: 95 REIRLQLKAIEPQKEEADENYNSVNTRMRKTQHGVLSQQFVELINKCNSMQSEY--REKN 152
Query: 190 REERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEE-------REREIRQ 242
E + T+ ++ D + + G +E + + ++T + + R EI+Q
Sbjct: 153 VERIRRQLKITNAGMVSDEELEQMLDSGQSEVFVSNILKDTQVTRQALNEISARHSEIQQ 212
Query: 243 IVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKM 302
+ +SI +L++IF L + QG +++RI+ N+ S E G + + A + QKK RK
Sbjct: 213 LERSIRELHDIFTFLATEVEMQGEMINRIEKNILSSADYVERGQEHVKTALENQKKARKK 272
Query: 303 LVILILFV-IIIVLIVVLVGV 322
V++ + V I +VL+ V++GV
Sbjct: 273 KVLIAICVSITVVLLAVIIGV 293
>gi|94400932 syntaxin 5 [Homo sapiens]
Length = 355
Score = 60.1 bits (144), Expect = 3e-09
Identities = 61/255 (23%), Positives = 107/255 (41%), Gaps = 29/255 (11%)
Query: 88 DVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRA 147
D+ K+++L L + + DD + E IE T I Q + + + L
Sbjct: 104 DLSNTFAKLEKLTILAKR---KSLFDDKAVE---IEELTYIIKQDINSLNKQIAQLQDFV 157
Query: 148 RACSEQEGRLL----GNVVASLAQALQELSTSFR---HAQSGYLKRMKNREERSQHFFDT 200
RA Q GR L +V SL L +S F+ ++ LK+ ++R E+ +
Sbjct: 158 RAKGSQSGRHLQTHSNTIVVSLQSKLASMSNDFKSVLEVRTENLKQQRSRREQFSRAPVS 217
Query: 201 SVPLMDDGDDNTLYHRGF----------------TEDQLVLVEQNTLMVEEREREIRQIV 244
++PL + G T QL L+++ ++ R ++ I
Sbjct: 218 ALPLAPNHLGGGAVVLGAESHASKDVAIDMMDSRTSQQLQLIDEQDSYIQSRADTMQNIE 277
Query: 245 QSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLV 304
+I +L IF+ L M+ EQ + RID NV + + E ++ K Q NR ++V
Sbjct: 278 STIVELGSIFQQLAHMVKEQEETIQRIDENVLGAQLDVEAAHSEILKYFQSVTSNRWLMV 337
Query: 305 ILILFVIIIVLIVVL 319
+ L +I+ +I V+
Sbjct: 338 KIFLILIVFFIIFVV 352
>gi|223972648 t-SNARE domain containing 1 [Homo sapiens]
Length = 513
Score = 52.4 bits (124), Expect = 6e-07
Identities = 58/278 (20%), Positives = 113/278 (40%), Gaps = 28/278 (10%)
Query: 59 GISLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEE 118
G SL+P A T+ P + E+ +V RI + SL + T D+ E
Sbjct: 241 GFSLEPPRA---TQVDPCNLQELFQEMSANVFRINSSV---TSLERSLQSLGTPSDTQEL 294
Query: 119 EHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRH 178
++ QE + +V+ + R+ QE + L L T
Sbjct: 295 RDSLHTAQQETNKTIAASASSVKQMAELLRSSCPQER------LQQERPQLDRLKTQLSD 348
Query: 179 AQSGYLKRMKNREERSQHFFDTS---------VPLMDDGDDNTLYHRGFT----EDQLVL 225
A Y K E+S+ + P + DD +++ ++Q +L
Sbjct: 349 AIQCYGVVQKKIAEKSRALLPMAQRGSKQSPQAPFAELADDEKVFNGSDNMWQGQEQALL 408
Query: 226 ---VEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKT 282
E++ + RE I Q+ ++ D+N+I +DL +M+ EQG +D I+ ++E +
Sbjct: 409 PDITEEDLEAIRLREEAILQMESNLLDVNQIIKDLASMVSEQGEAVDSIEASLEAASSHA 468
Query: 283 EDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIVVLV 320
E + L A ++Q + K+ + + +L+++++
Sbjct: 469 EAARQLLAGASRHQLQRHKIKCCFLSAGVTALLVIIII 506
>gi|33667038 syntaxin 11 [Homo sapiens]
Length = 287
Score = 48.1 bits (113), Expect = 1e-05
Identities = 54/225 (24%), Positives = 102/225 (45%), Gaps = 25/225 (11%)
Query: 88 DVGRI-KQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSR 146
DV R+ KQ + L S+ L + ++I + ++ H RA++ L
Sbjct: 61 DVKRLGKQNARFLTSMR-------RLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEA 113
Query: 147 ARACSEQEGRLLGNVVASLAQA-LQELSTSFRHAQSGY----LKRMKNREERSQHFFDTS 201
A A Q G + VA +++A L+ +F+ A Y +K+ N + R Q +
Sbjct: 114 AEA---QHGP--HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIM 168
Query: 202 VPLMDDGDDNTLYHRG----FTEDQLVLVEQNTLM---VEEREREIRQIVQSISDLNEIF 254
+ ++ +G F+E+ L V+ +E R RE+ ++ I D++E+F
Sbjct: 169 GKEVSGDQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELF 228
Query: 255 RDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKN 299
+ ++ +Q L+ I+ NV+++ T Q+ KA QY++KN
Sbjct: 229 LQMAVLVEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKN 273
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 42.4 bits (98), Expect = 6e-04
Identities = 48/227 (21%), Positives = 95/227 (41%), Gaps = 28/227 (12%)
Query: 78 WVDGVDEIQYDVGRIKQKMKELA-SLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRC 136
+V + +++ V + QK + L +L K + L++ EE ++ + I H+
Sbjct: 286 YVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEE---SVSKKNIQATLHQK 342
Query: 137 QRAVQALPSRARACSEQEGRL------LGNVVASLAQALQELSTSFRHAQSGYLKRMKNR 190
Q L SR A R+ G L + L E+ T ++H ++ + + + R
Sbjct: 343 DLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQR 402
Query: 191 EERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIV---QSI 247
EE+ QH L + N L H E + L E + + E+R+ +++ Q +
Sbjct: 403 EEKEQH------GLQLQSEINQL-HSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQV 455
Query: 248 SDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQ 294
+DL L + E+ T + + ++++ KQ H+ +Q
Sbjct: 456 ADLQLKLSRLEEQLKEKVTNSTELQHQLDKT--------KQQHQEQQ 494
>gi|49258196 syntaxin 19 [Homo sapiens]
Length = 294
Score = 40.8 bits (94), Expect = 0.002
Identities = 25/102 (24%), Positives = 51/102 (50%), Gaps = 7/102 (6%)
Query: 205 MDDGDDNTLYHRGFTE--DQLVLVEQNTLM-----VEEREREIRQIVQSISDLNEIFRDL 257
M + D N + H+G E ++ +L E N +E+R +E+ + I DL ++F +
Sbjct: 177 MSEEDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQI 236
Query: 258 GAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKN 299
++ EQG ++ I+ V + + ++ A +Y+K+N
Sbjct: 237 SLLVEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKRN 278
>gi|4507285 syntaxin 10 [Homo sapiens]
Length = 249
Score = 38.1 bits (87), Expect = 0.011
Identities = 18/89 (20%), Positives = 48/89 (53%)
Query: 231 LMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLH 290
L+++E+++++ + SI L + +G + EQG +LD ++ + + + L++L
Sbjct: 158 LIMDEQDQQLEMVSGSIQVLKHMSGRVGEELDEQGIMLDAFAQEMDHTQSRMDGVLRKLA 217
Query: 291 KAEQYQKKNRKMLVILILFVIIIVLIVVL 319
K R+ I +L ++++++++L
Sbjct: 218 KVSHMTSDRRQWCAIAVLVGVLLLVLILL 246
>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
[Homo sapiens]
Length = 8749
Score = 37.7 bits (86), Expect = 0.014
Identities = 45/179 (25%), Positives = 79/179 (44%), Gaps = 42/179 (23%)
Query: 122 IEITTQEITQLFHRCQRAVQALPSRA--RACSEQEG-RLLGNVVASLAQALQELSTSFRH 178
IE+TTQ +++L + R + A A S Q+G R + + VA L +A+ EL+
Sbjct: 4609 IELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGEAVDELN----- 4663
Query: 179 AQSGYLKRMKNREERSQHFFDTSVPLMDDGDDN--TLYHR--GFTEDQLVLVEQNTL--- 231
++ + F T P D + TLYHR TE ++ L+E T
Sbjct: 4664 -------------QKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQ 4710
Query: 232 ----MVEEREREIRQIVQSISDLNE----------IFRDLGAMIVEQGTVLDRIDYNVE 276
M ++ ER+++ + + S +NE ++ L + + G VL R+ ++E
Sbjct: 4711 EHEKMCQQLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLE 4769
>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
[Homo sapiens]
Length = 8797
Score = 37.7 bits (86), Expect = 0.014
Identities = 45/179 (25%), Positives = 79/179 (44%), Gaps = 42/179 (23%)
Query: 122 IEITTQEITQLFHRCQRAVQALPSRA--RACSEQEG-RLLGNVVASLAQALQELSTSFRH 178
IE+TTQ +++L + R + A A S Q+G R + + VA L +A+ EL+
Sbjct: 4680 IELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGEAVDELN----- 4734
Query: 179 AQSGYLKRMKNREERSQHFFDTSVPLMDDGDDN--TLYHR--GFTEDQLVLVEQNTL--- 231
++ + F T P D + TLYHR TE ++ L+E T
Sbjct: 4735 -------------QKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQ 4781
Query: 232 ----MVEEREREIRQIVQSISDLNE----------IFRDLGAMIVEQGTVLDRIDYNVE 276
M ++ ER+++ + + S +NE ++ L + + G VL R+ ++E
Sbjct: 4782 EHEKMCQQLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLE 4840
>gi|4504063 golgin 97 [Homo sapiens]
Length = 767
Score = 37.7 bits (86), Expect = 0.014
Identities = 48/239 (20%), Positives = 101/239 (42%), Gaps = 21/239 (8%)
Query: 18 IQNRQLLAEQVSSHITSSPLHSRSIAAELDELADDRMALVSGISLDPEAAIGVTKRPPPK 77
+Q E+ H+ +S + S L++ + AL+ +S+D + T+
Sbjct: 233 LQRHYSTLEEQRDHVIASKTGAESKITALEQKEQELQALIQQLSIDLQKVTAETQEKE-- 290
Query: 78 WVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQ 137
D + +Q V +++++++ S ++H+ + L + + E +E T Q++
Sbjct: 291 --DVITHLQEKVASLEKRLEQNLS-GEEHV-QELLKEKTLAEQNLEDTRQQLLAARSSQA 346
Query: 138 RAVQALPSRAR------ACSEQEGRLLGNVVASLAQALQELSTSFR---HAQSGYLKRMK 188
+A+ L +R R SE++ + +VA+ +QEL+ + + H Q L +
Sbjct: 347 KAINTLETRVRELEQTLQASEEQLQQSKGIVAAQETQIQELAAANQESSHVQQQALALEQ 406
Query: 189 NREERSQHFFDTSVPL-MDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQS 246
ER+Q V L D T +G + +EQ ++E E + +Q+
Sbjct: 407 QFLERTQALEAQIVALERTRAADQTTAEQGMRQ-----LEQENAALKECRNEYERSLQN 460
>gi|110611218 ribosome binding protein 1 [Homo sapiens]
Length = 977
Score = 36.6 bits (83), Expect = 0.031
Identities = 50/261 (19%), Positives = 104/261 (39%), Gaps = 19/261 (7%)
Query: 2 ATRRLTDAFLLLRNNSIQNRQLLAEQVSSHITSSPLH--SRSIAAELDELADDRMALVSG 59
AT++ +L R + + L EQ + + S L ++ +AAE + A +
Sbjct: 255 ATQKGDPVAILKRQLEEKEKLLATEQEDAAVAKSKLRELNKEMAAEKAKAAAGEAKVKKQ 314
Query: 60 ISLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEE 119
+ + V R + + V E+Q G+I+ ++L + + L R ++S +
Sbjct: 315 LVAREQEITAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRD 374
Query: 120 HAIEITTQ-------EITQLFHRCQRAVQALPSRARAC--SEQEGRLLGNVVASLAQALQ 170
+ T+Q E+ +L + + L ++ A EQ+ + L A+ + +
Sbjct: 375 ALNQATSQVESKQNAELAKLRQELSKVSKELVEKSEAVRQDEQQRKALEAKAAAFEKQVL 434
Query: 171 ELSTSFRHAQSGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNT 230
+L S R ++ KR+ H + L D + E Q + E ++
Sbjct: 435 QLQASHRESEEALQKRLDEVSRELCHTQSSHASLRADAEK-------AQEQQQQMAELHS 487
Query: 231 LMVEEREREIRQIVQSISDLN 251
++ E E+R + +S L+
Sbjct: 488 -KLQSSEAEVRSKCEELSGLH 507
>gi|110611220 ribosome binding protein 1 [Homo sapiens]
Length = 977
Score = 36.6 bits (83), Expect = 0.031
Identities = 50/261 (19%), Positives = 104/261 (39%), Gaps = 19/261 (7%)
Query: 2 ATRRLTDAFLLLRNNSIQNRQLLAEQVSSHITSSPLH--SRSIAAELDELADDRMALVSG 59
AT++ +L R + + L EQ + + S L ++ +AAE + A +
Sbjct: 255 ATQKGDPVAILKRQLEEKEKLLATEQEDAAVAKSKLRELNKEMAAEKAKAAAGEAKVKKQ 314
Query: 60 ISLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEE 119
+ + V R + + V E+Q G+I+ ++L + + L R ++S +
Sbjct: 315 LVAREQEITAVQARMQASYREHVKEVQQLQGKIRTLQEQLENGPNTQLARLQQENSILRD 374
Query: 120 HAIEITTQ-------EITQLFHRCQRAVQALPSRARAC--SEQEGRLLGNVVASLAQALQ 170
+ T+Q E+ +L + + L ++ A EQ+ + L A+ + +
Sbjct: 375 ALNQATSQVESKQNAELAKLRQELSKVSKELVEKSEAVRQDEQQRKALEAKAAAFEKQVL 434
Query: 171 ELSTSFRHAQSGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNT 230
+L S R ++ KR+ H + L D + E Q + E ++
Sbjct: 435 QLQASHRESEEALQKRLDEVSRELCHTQSSHASLRADAEK-------AQEQQQQMAELHS 487
Query: 231 LMVEEREREIRQIVQSISDLN 251
++ E E+R + +S L+
Sbjct: 488 -KLQSSEAEVRSKCEELSGLH 507
>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 36.6 bits (83), Expect = 0.031
Identities = 45/203 (22%), Positives = 83/203 (40%), Gaps = 25/203 (12%)
Query: 103 HDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVV 162
H+K L EE AI + Q+FH+ Q A +L + A + EG+ V+
Sbjct: 335 HEKQDTLVALRQQLEEVKAINL------QMFHKAQNAESSLQQKNEAITSFEGK-TNQVM 387
Query: 163 ASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQ 222
+S+ Q + L S R Q + K ++E + L + + + ++
Sbjct: 388 SSMKQMEERLQHSERARQGAEERSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEK 447
Query: 223 LVLVEQNTLMVEERERE------IRQIVQSISDLNEIFR-------DLGAMIVEQGTVLD 269
EQ + E + E +R +Q + L + R +L + EQ L
Sbjct: 448 ----EQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKICEEQEQALQ 503
Query: 270 RIDYNVEQSCIKTEDGLKQLHKA 292
+ ++ QS +K ED +K++++A
Sbjct: 504 EMGLHLSQSKLKMED-IKEVNQA 525
>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 36.6 bits (83), Expect = 0.031
Identities = 45/203 (22%), Positives = 83/203 (40%), Gaps = 25/203 (12%)
Query: 103 HDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVV 162
H+K L EE AI + Q+FH+ Q A +L + A + EG+ V+
Sbjct: 335 HEKQDTLVALRQQLEEVKAINL------QMFHKAQNAESSLQQKNEAITSFEGK-TNQVM 387
Query: 163 ASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQ 222
+S+ Q + L S R Q + K ++E + L + + + ++
Sbjct: 388 SSMKQMEERLQHSERARQGAEERSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEK 447
Query: 223 LVLVEQNTLMVEERERE------IRQIVQSISDLNEIFR-------DLGAMIVEQGTVLD 269
EQ + E + E +R +Q + L + R +L + EQ L
Sbjct: 448 ----EQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKICEEQEQALQ 503
Query: 270 RIDYNVEQSCIKTEDGLKQLHKA 292
+ ++ QS +K ED +K++++A
Sbjct: 504 EMGLHLSQSKLKMED-IKEVNQA 525
>gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo
sapiens]
Length = 708
Score = 36.6 bits (83), Expect = 0.031
Identities = 45/203 (22%), Positives = 83/203 (40%), Gaps = 25/203 (12%)
Query: 103 HDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVV 162
H+K L EE AI + Q+FH+ Q A +L + A + EG+ V+
Sbjct: 443 HEKQDTLVALRQQLEEVKAINL------QMFHKAQNAESSLQQKNEAITSFEGK-TNQVM 495
Query: 163 ASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQ 222
+S+ Q + L S R Q + K ++E + L + + + ++
Sbjct: 496 SSMKQMEERLQHSERARQGAEERSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEK 555
Query: 223 LVLVEQNTLMVEERERE------IRQIVQSISDLNEIFR-------DLGAMIVEQGTVLD 269
EQ + E + E +R +Q + L + R +L + EQ L
Sbjct: 556 ----EQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKICEEQEQALQ 611
Query: 270 RIDYNVEQSCIKTEDGLKQLHKA 292
+ ++ QS +K ED +K++++A
Sbjct: 612 EMGLHLSQSKLKMED-IKEVNQA 633
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 36.2 bits (82), Expect = 0.041
Identities = 61/301 (20%), Positives = 124/301 (41%), Gaps = 32/301 (10%)
Query: 13 LRNNSIQNRQLLAEQVSSHITSSPLHSRSIAAELDELADDRMALVSGIS-LDPEAAIGVT 71
L ++ ++ LAE + ++ + AE ++ R L ++ L EAA
Sbjct: 1689 LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQ 1748
Query: 72 KRPPPKWVDGVDEIQYDVGRIKQKMKEL--ASLHDKHLNRPTLDDSSEEEHAIEITTQEI 129
KR E++ ++ +++ +M+ L + + +R T + S + A +E+
Sbjct: 1749 KR---------QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1799
Query: 130 TQLFHRCQRAVQALPSRARACSEQEG--------RLLGNVVASLAQALQ-----ELSTSF 176
+ R RA+ R R +E++ R+L +A++ +A + E++
Sbjct: 1800 AEEAARL-RALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKE 1858
Query: 177 RHAQSGYLKRMKNREE-RSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEE 235
+ A++ L+R+ E + + + + D ++ R ++ +L E+ +VE+
Sbjct: 1859 KEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSEL---ERQKGLVED 1915
Query: 236 REREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQY 295
R+ RQ+ + I L F A E L RI N E + E +L A Q
Sbjct: 1916 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQA--ELEAARQR 1973
Query: 296 Q 296
Q
Sbjct: 1974 Q 1974
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 36.2 bits (82), Expect = 0.041
Identities = 61/301 (20%), Positives = 124/301 (41%), Gaps = 32/301 (10%)
Query: 13 LRNNSIQNRQLLAEQVSSHITSSPLHSRSIAAELDELADDRMALVSGIS-LDPEAAIGVT 71
L ++ ++ LAE + ++ + AE ++ R L ++ L EAA
Sbjct: 1693 LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQ 1752
Query: 72 KRPPPKWVDGVDEIQYDVGRIKQKMKEL--ASLHDKHLNRPTLDDSSEEEHAIEITTQEI 129
KR E++ ++ +++ +M+ L + + +R T + S + A +E+
Sbjct: 1753 KR---------QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1803
Query: 130 TQLFHRCQRAVQALPSRARACSEQEG--------RLLGNVVASLAQALQ-----ELSTSF 176
+ R RA+ R R +E++ R+L +A++ +A + E++
Sbjct: 1804 AEEAARL-RALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKE 1862
Query: 177 RHAQSGYLKRMKNREE-RSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEE 235
+ A++ L+R+ E + + + + D ++ R ++ +L E+ +VE+
Sbjct: 1863 KEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSEL---ERQKGLVED 1919
Query: 236 REREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQY 295
R+ RQ+ + I L F A E L RI N E + E +L A Q
Sbjct: 1920 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQA--ELEAARQR 1977
Query: 296 Q 296
Q
Sbjct: 1978 Q 1978
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 36.2 bits (82), Expect = 0.041
Identities = 61/301 (20%), Positives = 124/301 (41%), Gaps = 32/301 (10%)
Query: 13 LRNNSIQNRQLLAEQVSSHITSSPLHSRSIAAELDELADDRMALVSGIS-LDPEAAIGVT 71
L ++ ++ LAE + ++ + AE ++ R L ++ L EAA
Sbjct: 1689 LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQ 1748
Query: 72 KRPPPKWVDGVDEIQYDVGRIKQKMKEL--ASLHDKHLNRPTLDDSSEEEHAIEITTQEI 129
KR E++ ++ +++ +M+ L + + +R T + S + A +E+
Sbjct: 1749 KR---------QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1799
Query: 130 TQLFHRCQRAVQALPSRARACSEQEG--------RLLGNVVASLAQALQ-----ELSTSF 176
+ R RA+ R R +E++ R+L +A++ +A + E++
Sbjct: 1800 AEEAARL-RALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKE 1858
Query: 177 RHAQSGYLKRMKNREE-RSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEE 235
+ A++ L+R+ E + + + + D ++ R ++ +L E+ +VE+
Sbjct: 1859 KEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSEL---ERQKGLVED 1915
Query: 236 REREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQY 295
R+ RQ+ + I L F A E L RI N E + E +L A Q
Sbjct: 1916 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQA--ELEAARQR 1973
Query: 296 Q 296
Q
Sbjct: 1974 Q 1974
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 36.2 bits (82), Expect = 0.041
Identities = 61/301 (20%), Positives = 124/301 (41%), Gaps = 32/301 (10%)
Query: 13 LRNNSIQNRQLLAEQVSSHITSSPLHSRSIAAELDELADDRMALVSGIS-LDPEAAIGVT 71
L ++ ++ LAE + ++ + AE ++ R L ++ L EAA
Sbjct: 1657 LAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQ 1716
Query: 72 KRPPPKWVDGVDEIQYDVGRIKQKMKEL--ASLHDKHLNRPTLDDSSEEEHAIEITTQEI 129
KR E++ ++ +++ +M+ L + + +R T + S + A +E+
Sbjct: 1717 KR---------QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFREL 1767
Query: 130 TQLFHRCQRAVQALPSRARACSEQEG--------RLLGNVVASLAQALQ-----ELSTSF 176
+ R RA+ R R +E++ R+L +A++ +A + E++
Sbjct: 1768 AEEAARL-RALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKE 1826
Query: 177 RHAQSGYLKRMKNREE-RSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEE 235
+ A++ L+R+ E + + + + D ++ R ++ +L E+ +VE+
Sbjct: 1827 KEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSEL---ERQKGLVED 1883
Query: 236 REREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQY 295
R+ RQ+ + I L F A E L RI N E + E +L A Q
Sbjct: 1884 TLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQA--ELEAARQR 1941
Query: 296 Q 296
Q
Sbjct: 1942 Q 1942
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,746,978
Number of Sequences: 37866
Number of extensions: 436796
Number of successful extensions: 2018
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 70
Number of HSP's that attempted gapping in prelim test: 1930
Number of HSP's gapped (non-prelim): 162
length of query: 325
length of database: 18,247,518
effective HSP length: 102
effective length of query: 223
effective length of database: 14,385,186
effective search space: 3207896478
effective search space used: 3207896478
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.