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Search of human proteins with 4759274
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4759274 thioredoxin-like 1 [Homo sapiens]
(289 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4759274 thioredoxin-like 1 [Homo sapiens] 592 e-169
gi|50592994 thioredoxin [Homo sapiens] 86 4e-17
gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo sap... 74 1e-13
gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo sap... 74 1e-13
gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo sapi... 74 1e-13
gi|51510891 thioredoxin domain containing 8 [Homo sapiens] 65 7e-11
gi|21361837 chromosome 1 open reading frame 128 [Homo sapiens] 60 2e-09
gi|95113651 glutaredoxin 3 [Homo sapiens] 59 5e-09
gi|42794771 thioredoxin domain containing 5 isoform 1 precursor ... 48 1e-05
gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo sap... 48 1e-05
gi|21361403 thioredoxin 2 precursor [Homo sapiens] 43 4e-04
gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens] 40 0.002
gi|148839372 thioredoxin domain containing 3 [Homo sapiens] 36 0.045
gi|94421469 disulfide isomerase [Homo sapiens] 33 0.22
gi|4501867 aconitase 2, mitochondrial precursor [Homo sapiens] 32 0.65
gi|52487191 thioredoxin domain containing 4 (endoplasmic reticul... 31 1.1
gi|94966757 protein disulfide isomerase A2 [Homo sapiens] 31 1.4
gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo s... 30 1.9
gi|119943110 cystinosis, nephropathic isoform 2 [Homo sapiens] 30 1.9
gi|119943118 cystinosis, nephropathic isoform 1 [Homo sapiens] 30 1.9
gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo s... 30 2.5
gi|56676379 intraflagellar transport 52 homolog [Homo sapiens] 30 2.5
gi|4758304 protein disulfide isomerase A4 [Homo sapiens] 30 3.2
gi|5031973 protein disulfide isomerase A6 [Homo sapiens] 29 4.2
gi|51873067 quiescin Q6 sulfhydryl oxidase 1 isoform b [Homo sap... 29 4.2
gi|13325075 quiescin Q6 sulfhydryl oxidase 1 isoform a [Homo sap... 29 4.2
gi|5453998 importin 7 [Homo sapiens] 28 7.2
>gi|4759274 thioredoxin-like 1 [Homo sapiens]
Length = 289
Score = 592 bits (1525), Expect = e-169
Identities = 289/289 (100%), Positives = 289/289 (100%)
Query: 1 MVGVKPVGSDPDFQPELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVD 60
MVGVKPVGSDPDFQPELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVD
Sbjct: 1 MVGVKPVGSDPDFQPELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVD 60
Query: 61 VHQCQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKIKQHLENDPGSNEDTDIP 120
VHQCQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKIKQHLENDPGSNEDTDIP
Sbjct: 61 VHQCQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKIKQHLENDPGSNEDTDIP 120
Query: 121 KGYMDLMPFINKAGCECLNESDEHGFDNCLRKDTTFLESDCDEQLLITVAFNQPVKLYSM 180
KGYMDLMPFINKAGCECLNESDEHGFDNCLRKDTTFLESDCDEQLLITVAFNQPVKLYSM
Sbjct: 121 KGYMDLMPFINKAGCECLNESDEHGFDNCLRKDTTFLESDCDEQLLITVAFNQPVKLYSM 180
Query: 181 KFQGPDNGQGPKYVKIFINLPRSMDFEEAERSEPTQALELTEDDIKEDGIVPLRYVKFQN 240
KFQGPDNGQGPKYVKIFINLPRSMDFEEAERSEPTQALELTEDDIKEDGIVPLRYVKFQN
Sbjct: 181 KFQGPDNGQGPKYVKIFINLPRSMDFEEAERSEPTQALELTEDDIKEDGIVPLRYVKFQN 240
Query: 241 VNSVTIFVQSNQGEEETTRISYFTFIGTPVQATNMNDFKRVVGKKGESH 289
VNSVTIFVQSNQGEEETTRISYFTFIGTPVQATNMNDFKRVVGKKGESH
Sbjct: 241 VNSVTIFVQSNQGEEETTRISYFTFIGTPVQATNMNDFKRVVGKKGESH 289
>gi|50592994 thioredoxin [Homo sapiens]
Length = 105
Score = 85.9 bits (211), Expect = 4e-17
Identities = 42/102 (41%), Positives = 56/102 (54%)
Query: 4 VKPVGSDPDFQPELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVDVHQ 63
VK + S FQ L AG +L VV F+ CGPC I P F S+S KY +FLEVDV
Sbjct: 2 VKQIESKTAFQEALDAAGDKLVVVDFSATWCGPCKMIKPFFHSLSEKYSNVIFLEVDVDD 61
Query: 64 CQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKIKQ 105
CQ A+ + PTF FF+ ++ ++ GA+ LE I +
Sbjct: 62 CQDVASECEVKCMPTFQFFKKGQKVGEFSGANKEKLEATINE 103
>gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo
sapiens]
Length = 486
Score = 73.9 bits (180), Expect = 1e-13
Identities = 39/101 (38%), Positives = 55/101 (54%), Gaps = 4/101 (3%)
Query: 4 VKPVGSDPDFQPELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVDVHQ 63
VK + S DF+ L AG RL V F+ CGPC I P F ++S K+ VFLEVD
Sbjct: 383 VKVILSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFHALSVKHEDVVFLEVDADN 442
Query: 64 CQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKIK 104
C+ I PTF F++ + ++D+ GA L+EK++
Sbjct: 443 CEEVVRECAIMCVPTFQFYKKEEKVDELCGA----LKEKLE 479
>gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo
sapiens]
Length = 553
Score = 73.9 bits (180), Expect = 1e-13
Identities = 39/101 (38%), Positives = 55/101 (54%), Gaps = 4/101 (3%)
Query: 4 VKPVGSDPDFQPELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVDVHQ 63
VK + S DF+ L AG RL V F+ CGPC I P F ++S K+ VFLEVD
Sbjct: 450 VKVILSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFHALSVKHEDVVFLEVDADN 509
Query: 64 CQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKIK 104
C+ I PTF F++ + ++D+ GA L+EK++
Sbjct: 510 CEEVVRECAIMCVPTFQFYKKEEKVDELCGA----LKEKLE 546
>gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo
sapiens]
Length = 486
Score = 73.9 bits (180), Expect = 1e-13
Identities = 39/101 (38%), Positives = 55/101 (54%), Gaps = 4/101 (3%)
Query: 4 VKPVGSDPDFQPELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVDVHQ 63
VK + S DF+ L AG RL V F+ CGPC I P F ++S K+ VFLEVD
Sbjct: 383 VKVILSKEDFEASLKEAGERLVAVDFSATWCGPCRTIRPFFHALSVKHEDVVFLEVDADN 442
Query: 64 CQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKIK 104
C+ I PTF F++ + ++D+ GA L+EK++
Sbjct: 443 CEEVVRECAIMCVPTFQFYKKEEKVDELCGA----LKEKLE 479
>gi|51510891 thioredoxin domain containing 8 [Homo sapiens]
Length = 115
Score = 65.1 bits (157), Expect = 7e-11
Identities = 31/77 (40%), Positives = 45/77 (58%)
Query: 12 DFQPELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVDVHQCQGTAATN 71
+F+ L+ AG +LAVV+F+ + CGPC R+ P F +MS KY F VDV+ A T
Sbjct: 10 EFKTFLTAAGHKLAVVQFSSKRCGPCKRMFPVFHAMSVKYQNVFFANVDVNNSPELAETC 69
Query: 72 NISATPTFLFFRNKVRI 88
+I PTF F+ ++
Sbjct: 70 HIKTIPTFQMFKKSQKV 86
>gi|21361837 chromosome 1 open reading frame 128 [Homo sapiens]
Length = 211
Score = 60.5 bits (145), Expect = 2e-09
Identities = 42/138 (30%), Positives = 68/138 (49%), Gaps = 10/138 (7%)
Query: 136 ECLNESDEHGFDNCLRK------DTTFLESDCDEQLLITVAFNQPVKLYSMKFQGPDNGQ 189
+CLNES E + + F+ESD DE+LL + F VKL + G D+
Sbjct: 41 QCLNESREGSGRGVFKPWEERTDRSKFVESDADEELLFNIPFTGNVKLKGIIIMGEDDDS 100
Query: 190 GPKYVKIFINLPRSMDFEEAERSEPTQALELTEDDIKEDGIVPLRYVKFQNVNSVTIFVQ 249
P ++++ N+P+ M F++ ER EP Q L D+ + + +F NV ++I +
Sbjct: 101 HPSEMRLYKNIPQ-MSFDDTER-EPDQTFSLNR-DLTGELEYATKISRFSNVYHLSIHIS 157
Query: 250 SNQGEEETTRISYFTFIG 267
N G +TT++ Y G
Sbjct: 158 KNFG-ADTTKVFYIGLRG 174
>gi|95113651 glutaredoxin 3 [Homo sapiens]
Length = 335
Score = 58.9 bits (141), Expect = 5e-09
Identities = 34/118 (28%), Positives = 58/118 (49%), Gaps = 3/118 (2%)
Query: 1 MVGVKPVGSDPDFQPELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVD 60
+ V+ VGS F+ L L VV F C ++ + ++ + PQ F++++
Sbjct: 10 VAAVEEVGSAGQFEELLRLKAKSLLVVHFWAPWAPQCAQMNEVMAELAKELPQVSFVKLE 69
Query: 61 VHQCQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKIKQHLEND---PGSNE 115
+ IS+ PTFLFF+N +ID+ GA A L +K+++H + P +NE
Sbjct: 70 AEGVPEVSEKYEISSVPTFLFFKNSQKIDRLDGAHAPELTKKVQRHASSGSFLPSANE 127
>gi|42794771 thioredoxin domain containing 5 isoform 1 precursor
[Homo sapiens]
Length = 432
Score = 47.8 bits (112), Expect = 1e-05
Identities = 44/177 (24%), Positives = 79/177 (44%), Gaps = 26/177 (14%)
Query: 5 KPVGSDPDFQP-----------ELSGAGSRLAV------VKFTMRGCGPCLRIAPAFSSM 47
+PV +P+ +P ELS + L V +KF CG C +AP + +
Sbjct: 171 EPVTPEPEVEPPSAPELKQGLYELSASNFELHVAQGDHFIKFFAPWCGHCKALAPTWEQL 230
Query: 48 SN--KYPQAVFL-EVDVHQCQGTAATNNISATPTFLFFRNKVRIDQYQG-ADAVGLEEKI 103
+ ++ + V + +VD Q + N + PT L+FR+ ++DQY+G D L E +
Sbjct: 231 ALGLEHSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFRDGKKVDQYKGKRDLESLREYV 290
Query: 104 KQHLENDPGSNEDTDIPK--GYMDLMPFINKAGCECLNESDEHGFDNCLRKDTTFLE 158
+ L+ +T P + P +K L E++ FD+ + + TF++
Sbjct: 291 ESQLQRTETGATETVTPSEAPVLAAEPEADKGTVLALTENN---FDDTIAEGITFIK 344
Score = 34.7 bits (78), Expect = 0.10
Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 6/103 (5%)
Query: 19 GAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVDVHQCQGTAATNNISAT-- 76
G S V F CG C R+ P ++ + +KY +V V + TA ++ SA
Sbjct: 74 GIQSAAHFVMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTAHSDVCSAQGV 133
Query: 77 ---PTFLFFRNKVRIDQYQG-ADAVGLEEKIKQHLENDPGSNE 115
PT F+ +YQG D LE + Q L +P + E
Sbjct: 134 RGYPTLKLFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPE 176
Score = 33.9 bits (76), Expect = 0.17
Identities = 19/74 (25%), Positives = 33/74 (44%), Gaps = 4/74 (5%)
Query: 24 LAVVKFTMRGCGPCLRIAPAFSSMSNK-YPQAV---FLEVDVHQCQGTAATNNISATPTF 79
+ +KF CG C +AP + +S K +P EVD + + ++ PT
Sbjct: 340 ITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYPTL 399
Query: 80 LFFRNKVRIDQYQG 93
L FR ++ ++ G
Sbjct: 400 LLFRGGKKVSEHSG 413
>gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo
sapiens]
Length = 324
Score = 47.8 bits (112), Expect = 1e-05
Identities = 44/177 (24%), Positives = 79/177 (44%), Gaps = 26/177 (14%)
Query: 5 KPVGSDPDFQP-----------ELSGAGSRLAV------VKFTMRGCGPCLRIAPAFSSM 47
+PV +P+ +P ELS + L V +KF CG C +AP + +
Sbjct: 63 EPVTPEPEVEPPSAPELKQGLYELSASNFELHVAQGDHFIKFFAPWCGHCKALAPTWEQL 122
Query: 48 SN--KYPQAVFL-EVDVHQCQGTAATNNISATPTFLFFRNKVRIDQYQG-ADAVGLEEKI 103
+ ++ + V + +VD Q + N + PT L+FR+ ++DQY+G D L E +
Sbjct: 123 ALGLEHSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFRDGKKVDQYKGKRDLESLREYV 182
Query: 104 KQHLENDPGSNEDTDIPK--GYMDLMPFINKAGCECLNESDEHGFDNCLRKDTTFLE 158
+ L+ +T P + P +K L E++ FD+ + + TF++
Sbjct: 183 ESQLQRTETGATETVTPSEAPVLAAEPEADKGTVLALTENN---FDDTIAEGITFIK 236
Score = 33.9 bits (76), Expect = 0.17
Identities = 19/74 (25%), Positives = 33/74 (44%), Gaps = 4/74 (5%)
Query: 24 LAVVKFTMRGCGPCLRIAPAFSSMSNK-YPQAV---FLEVDVHQCQGTAATNNISATPTF 79
+ +KF CG C +AP + +S K +P EVD + + ++ PT
Sbjct: 232 ITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYPTL 291
Query: 80 LFFRNKVRIDQYQG 93
L FR ++ ++ G
Sbjct: 292 LLFRGGKKVSEHSG 305
>gi|21361403 thioredoxin 2 precursor [Homo sapiens]
Length = 166
Score = 42.7 bits (99), Expect = 4e-04
Identities = 25/84 (29%), Positives = 42/84 (50%), Gaps = 2/84 (2%)
Query: 11 PDFQPELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSM-SNKYPQAVFLEVDVHQCQGTAA 69
PDFQ + + + + VV F + CGPC + P M + ++ + V +VD+ A
Sbjct: 68 PDFQDRVVNSETPV-VVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDIDDHTDLAI 126
Query: 70 TNNISATPTFLFFRNKVRIDQYQG 93
+SA PT L +N +D++ G
Sbjct: 127 EYEVSAVPTVLAMKNGDVVDKFVG 150
>gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens]
Length = 505
Score = 40.4 bits (93), Expect = 0.002
Identities = 30/106 (28%), Positives = 46/106 (43%), Gaps = 5/106 (4%)
Query: 9 SDPDFQPELSGAGSR-LAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFL-EVDVHQCQG 66
+D +F+ +S GS L +V+F CG C R+AP + + + + V L +VD
Sbjct: 31 TDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCTANTN 90
Query: 67 TAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKIKQHLENDPG 112
T +S PT FR+ Y G + I HL+ G
Sbjct: 91 TCNKYGVSGYPTLKIFRDGEEAGAYDGPRTA---DGIVSHLKKQAG 133
>gi|148839372 thioredoxin domain containing 3 [Homo sapiens]
Length = 588
Score = 35.8 bits (81), Expect = 0.045
Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 2/82 (2%)
Query: 24 LAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVDVHQCQG--TAATNNISATPTFLF 81
L V+ CGPC + P F + N+ + L V + T P FLF
Sbjct: 29 LTVIDVYQAWCGPCRAMQPLFRKLKNELNEDEILHFAVAEADNIVTLQPFRDKCEPVFLF 88
Query: 82 FRNKVRIDQYQGADAVGLEEKI 103
N I++ QGA+A + +K+
Sbjct: 89 SVNGKIIEKIQGANAPLVNKKV 110
>gi|94421469 disulfide isomerase [Homo sapiens]
Length = 360
Score = 33.5 bits (75), Expect = 0.22
Identities = 22/92 (23%), Positives = 36/92 (39%)
Query: 4 VKPVGSDPDFQPELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVDVHQ 63
+K + D L+ GS +V F C +AP F+S+ +P FL +D Q
Sbjct: 190 LKILNMSQDLMDFLNPNGSDCTLVLFYTPWCRFSASLAPHFNSLPRAFPALHFLALDASQ 249
Query: 64 CQGTAATNNISATPTFLFFRNKVRIDQYQGAD 95
+ A P L F+ + ++ D
Sbjct: 250 HSSLSTRFGTVAVPNILLFQGAKPMARFNHTD 281
>gi|4501867 aconitase 2, mitochondrial precursor [Homo sapiens]
Length = 780
Score = 32.0 bits (71), Expect = 0.65
Identities = 25/79 (31%), Positives = 33/79 (41%), Gaps = 6/79 (7%)
Query: 59 VDVHQCQGTAATNNISA-----TPTFLF-FRNKVRIDQYQGADAVGLEEKIKQHLENDPG 112
VD C G A N+ A T F + R K + + D L ++ K HL DPG
Sbjct: 272 VDSISCTGMATICNMGAEIGATTSVFPYNHRMKKYLSKTGREDIANLADEFKDHLVPDPG 331
Query: 113 SNEDTDIPKGYMDLMPFIN 131
+ D I +L P IN
Sbjct: 332 CHYDQLIEINLSELKPHIN 350
>gi|52487191 thioredoxin domain containing 4 (endoplasmic reticulum)
[Homo sapiens]
Length = 406
Score = 31.2 bits (69), Expect = 1.1
Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 10/97 (10%)
Query: 24 LAVVKFTMRGCGPCLRIAPAFSSMSN----KYP---QAVFLEVDVHQCQGTAATNNISAT 76
+A+V F C + P F S+ ++P Q VF VD Q A IS
Sbjct: 48 VALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKY 107
Query: 77 PTFLFFRNKVRID-QYQGADAV-GLEEKIKQHLENDP 111
PT FRN + + +Y+G +V L + I+Q ++DP
Sbjct: 108 PTLKLFRNGMMMKREYRGQRSVKALADYIRQQ-KSDP 143
>gi|94966757 protein disulfide isomerase A2 [Homo sapiens]
Length = 525
Score = 30.8 bits (68), Expect = 1.4
Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 7/89 (7%)
Query: 26 VVKFTMRGCGPCLRIAPAFSS----MSNKYPQAVFLEVDVHQCQGTAATNNISATPTFLF 81
+V+F CG C +AP +S ++ + +VD + A ++ PT F
Sbjct: 63 LVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLKF 122
Query: 82 FR--NKVRIDQYQG-ADAVGLEEKIKQHL 107
FR N+ ++Y G DA G+ E +++ +
Sbjct: 123 FRNGNRTHPEEYTGPRDAEGIAEWLRRRV 151
>gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo
sapiens]
Length = 793
Score = 30.4 bits (67), Expect = 1.9
Identities = 24/89 (26%), Positives = 34/89 (38%), Gaps = 6/89 (6%)
Query: 26 VVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFL-EVDVHQCQGTAATNNISATPTFLFF-- 82
V+ F CGPC AP F ++ V +VD T I A PT F+
Sbjct: 692 VIDFYAPWCGPCQNFAPEFELLARMIKGKVKAGKVDCQAYAQTCQKAGIRAYPTVKFYFY 751
Query: 83 ---RNKVRIDQYQGADAVGLEEKIKQHLE 108
+ + +Q DA + I + LE
Sbjct: 752 ERAKRNFQEEQINTRDAKAIAALISEKLE 780
>gi|119943110 cystinosis, nephropathic isoform 2 [Homo sapiens]
Length = 367
Score = 30.4 bits (67), Expect = 1.9
Identities = 18/78 (23%), Positives = 34/78 (43%), Gaps = 1/78 (1%)
Query: 198 INLPRSMDFEEAERSEPTQALELTEDDIKEDGIVPLRY-VKFQNVNSVTIFVQSNQGEEE 256
+N + FE RS+ LEL ++ + G+ + V QNV +T+++ N +
Sbjct: 50 LNATLVITFEITFRSKNITILELPDEVVVPPGVTNSSFQVTSQNVGQLTVYLHGNHSNQT 109
Query: 257 TTRISYFTFIGTPVQATN 274
RI + + + N
Sbjct: 110 GPRIRFLVIRSSAISIIN 127
>gi|119943118 cystinosis, nephropathic isoform 1 [Homo sapiens]
Length = 400
Score = 30.4 bits (67), Expect = 1.9
Identities = 18/78 (23%), Positives = 34/78 (43%), Gaps = 1/78 (1%)
Query: 198 INLPRSMDFEEAERSEPTQALELTEDDIKEDGIVPLRY-VKFQNVNSVTIFVQSNQGEEE 256
+N + FE RS+ LEL ++ + G+ + V QNV +T+++ N +
Sbjct: 50 LNATLVITFEITFRSKNITILELPDEVVVPPGVTNSSFQVTSQNVGQLTVYLHGNHSNQT 109
Query: 257 TTRISYFTFIGTPVQATN 274
RI + + + N
Sbjct: 110 GPRIRFLVIRSSAISIIN 127
>gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo
sapiens]
Length = 508
Score = 30.0 bits (66), Expect = 2.5
Identities = 18/69 (26%), Positives = 29/69 (42%), Gaps = 4/69 (5%)
Query: 20 AGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKY----PQAVFLEVDVHQCQGTAATNNISA 75
A + +V+F CG C +AP ++ + K + +VD + A +
Sbjct: 39 AAHKYLLVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRG 98
Query: 76 TPTFLFFRN 84
PT FFRN
Sbjct: 99 YPTIKFFRN 107
>gi|56676379 intraflagellar transport 52 homolog [Homo sapiens]
Length = 437
Score = 30.0 bits (66), Expect = 2.5
Identities = 37/131 (28%), Positives = 59/131 (45%), Gaps = 22/131 (16%)
Query: 115 EDTDIPKGYMDLMPF---INKAGCECLNESDEHGFD-------NCLRKDTTFLES--DCD 162
ED +I YM ++P+ ++K ECL ESDE D + + DTT S +
Sbjct: 253 EDPEI-SDYM-MLPYTATLSKRNRECLQESDEIPRDFTTLFDLSIFQLDTTSFHSVIEAH 310
Query: 163 EQLLITVAFNQPVKLYSMKFQGP-DNGQGPKYVKIFINLP----RSMDFEEAERSEPTQA 217
EQL + ++P++L +F+ P Q + F LP D +E SE +
Sbjct: 311 EQLNVK---HEPLQLIQPQFETPLPTLQPAVFPPSFRELPPPPLELFDLDETFSSEKARL 367
Query: 218 LELTEDDIKED 228
++T +ED
Sbjct: 368 AQITNKCTEED 378
>gi|4758304 protein disulfide isomerase A4 [Homo sapiens]
Length = 645
Score = 29.6 bits (65), Expect = 3.2
Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 5/74 (6%)
Query: 24 LAVVKFTMRGCGPCLRIAP----AFSSMSNKYPQAVFLEVDVHQCQGTAATNNISATPTF 79
+ +V+F CG C ++AP A +S + P +VD A ++S PT
Sbjct: 196 IILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDVSGYPTL 255
Query: 80 LFFRNKVRIDQYQG 93
FR K R Y G
Sbjct: 256 KIFR-KGRPYDYNG 268
Score = 28.9 bits (63), Expect = 5.5
Identities = 17/73 (23%), Positives = 33/73 (45%), Gaps = 5/73 (6%)
Query: 26 VVKFTMRGCGPCLRIAPAFSSMSN----KYPQAVFLEVDVHQCQGTAATNNISATPTFLF 81
+++F CG C + AP + ++N K P ++D A+ ++S PT
Sbjct: 83 LLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPTIKI 142
Query: 82 FRNKVRIDQYQGA 94
+ +D Y+G+
Sbjct: 143 LKKGQAVD-YEGS 154
>gi|5031973 protein disulfide isomerase A6 [Homo sapiens]
Length = 440
Score = 29.3 bits (64), Expect = 4.2
Identities = 20/72 (27%), Positives = 30/72 (41%), Gaps = 2/72 (2%)
Query: 24 LAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFL-EVDVHQCQGTAATNNISATPTF-LF 81
L +V+F CG C R+ P + + V + VD + + PT +F
Sbjct: 45 LWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIF 104
Query: 82 FRNKVRIDQYQG 93
NK R + YQG
Sbjct: 105 GSNKNRPEDYQG 116
>gi|51873067 quiescin Q6 sulfhydryl oxidase 1 isoform b [Homo
sapiens]
Length = 604
Score = 29.3 bits (64), Expect = 4.2
Identities = 27/101 (26%), Positives = 42/101 (41%), Gaps = 12/101 (11%)
Query: 21 GSRLA-VVKFTMRGCGPCLRIAPAFSSMSNKY----PQAVFLEVDVHQCQGTAATN--NI 73
GSR A V+F CG C+ AP + +++ P +D + +A NI
Sbjct: 56 GSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNI 115
Query: 74 SATPTFLFFRNKVR-----IDQYQGADAVGLEEKIKQHLEN 109
PT FF+ + + GAD L E++ LE+
Sbjct: 116 PGFPTVRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALES 156
>gi|13325075 quiescin Q6 sulfhydryl oxidase 1 isoform a [Homo
sapiens]
Length = 747
Score = 29.3 bits (64), Expect = 4.2
Identities = 27/101 (26%), Positives = 42/101 (41%), Gaps = 12/101 (11%)
Query: 21 GSRLA-VVKFTMRGCGPCLRIAPAFSSMSNKY----PQAVFLEVDVHQCQGTAATN--NI 73
GSR A V+F CG C+ AP + +++ P +D + +A NI
Sbjct: 56 GSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNI 115
Query: 74 SATPTFLFFRNKVR-----IDQYQGADAVGLEEKIKQHLEN 109
PT FF+ + + GAD L E++ LE+
Sbjct: 116 PGFPTVRFFKAFTKNGSGAVFPVAGADVQTLRERLIDALES 156
>gi|5453998 importin 7 [Homo sapiens]
Length = 1038
Score = 28.5 bits (62), Expect = 7.2
Identities = 18/50 (36%), Positives = 24/50 (48%), Gaps = 11/50 (22%)
Query: 191 PKYVKIFINLPR-----------SMDFEEAERSEPTQALELTEDDIKEDG 229
P ++ +F L R S D +EAE + T+ L EDDI EDG
Sbjct: 863 PAFILLFNGLKRAYACHAEHENDSDDDDEAEDDDETEELGSDEDDIDEDG 912
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,388,526
Number of Sequences: 37866
Number of extensions: 513293
Number of successful extensions: 947
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 922
Number of HSP's gapped (non-prelim): 35
length of query: 289
length of database: 18,247,518
effective HSP length: 101
effective length of query: 188
effective length of database: 14,423,052
effective search space: 2711533776
effective search space used: 2711533776
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.