Guide to the Human Genome
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Search of human proteins with 4758894

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4758894 PET112-like [Homo sapiens]
         (557 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4758894 PET112-like [Homo sapiens]                                1099   0.0  
gi|11545912 nucleotide-binding oligomerization domain containing...    32   1.5  
gi|31581534 tRNA isopentenyltransferase 1 [Homo sapiens]               31   2.6  
gi|157266317 ataxia telangiectasia and Rad3 related protein [Hom...    30   5.8  
gi|169218238 PREDICTED: similar to ataxia telangiectasia and Rad...    30   5.8  
gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapi...    30   5.8  
gi|20127519 TPX2, microtubule-associated protein homolog [Homo s...    30   7.6  
gi|157909822 pragmin [Homo sapiens]                                    30   7.6  
gi|23397678 signal transducer and activator of transcription 6 [...    29   9.9  
gi|21536423 amphiphysin isoform 2 [Homo sapiens]                       29   9.9  
gi|4502081 amphiphysin isoform 1 [Homo sapiens]                        29   9.9  
gi|82659109 retinoblastoma-associated factor 600 [Homo sapiens]        29   9.9  
gi|50083293 coiled-coil domain containing 123 [Homo sapiens]           29   9.9  

>gi|4758894 PET112-like [Homo sapiens]
          Length = 557

 Score = 1099 bits (2843), Expect = 0.0
 Identities = 557/557 (100%), Positives = 557/557 (100%)

Query: 1   MAAPMLRWGCRGRRWAFARVDGGSCHRRGAPTGSTSNQIRGESSVAQQPLHTAQKTRKGE 60
           MAAPMLRWGCRGRRWAFARVDGGSCHRRGAPTGSTSNQIRGESSVAQQPLHTAQKTRKGE
Sbjct: 1   MAAPMLRWGCRGRRWAFARVDGGSCHRRGAPTGSTSNQIRGESSVAQQPLHTAQKTRKGE 60

Query: 61  HKWAAVVGLEIHAQISSNSKLFSGSQVRFSAPPNSLVSFFDASLPGTLPVLNRRCVEAAV 120
           HKWAAVVGLEIHAQISSNSKLFSGSQVRFSAPPNSLVSFFDASLPGTLPVLNRRCVEAAV
Sbjct: 61  HKWAAVVGLEIHAQISSNSKLFSGSQVRFSAPPNSLVSFFDASLPGTLPVLNRRCVEAAV 120

Query: 121 MTGLALNCHINKKSLFDRKHYFYADLPAGYQITQQRLPIAVNGSLIYGVCAGKKQSQVIP 180
           MTGLALNCHINKKSLFDRKHYFYADLPAGYQITQQRLPIAVNGSLIYGVCAGKKQSQVIP
Sbjct: 121 MTGLALNCHINKKSLFDRKHYFYADLPAGYQITQQRLPIAVNGSLIYGVCAGKKQSQVIP 180

Query: 181 KTVRIKQIQLEQDSGKSLHDNLRSQTLIDLNRAGVGLLEVVLEPDMSCGEEAATAVRELQ 240
           KTVRIKQIQLEQDSGKSLHDNLRSQTLIDLNRAGVGLLEVVLEPDMSCGEEAATAVRELQ
Sbjct: 181 KTVRIKQIQLEQDSGKSLHDNLRSQTLIDLNRAGVGLLEVVLEPDMSCGEEAATAVRELQ 240

Query: 241 LILQALGTSQANMAEGQLRVDANISVHHPGEPLGVRTEVKNLNSIRFLAKAIDYEIQRQI 300
           LILQALGTSQANMAEGQLRVDANISVHHPGEPLGVRTEVKNLNSIRFLAKAIDYEIQRQI
Sbjct: 241 LILQALGTSQANMAEGQLRVDANISVHHPGEPLGVRTEVKNLNSIRFLAKAIDYEIQRQI 300

Query: 301 NELENGGEILNETRSFHHKLGCTMSMRDKEGKQDYRFMPEPNLPPLVLYDATSLPAGADP 360
           NELENGGEILNETRSFHHKLGCTMSMRDKEGKQDYRFMPEPNLPPLVLYDATSLPAGADP
Sbjct: 301 NELENGGEILNETRSFHHKLGCTMSMRDKEGKQDYRFMPEPNLPPLVLYDATSLPAGADP 360

Query: 361 QQVINIDQIRETLPELPSVTREKLVQQYGMLLEHSFTLLNEVGLLEFFQNVIKETRAEPK 420
           QQVINIDQIRETLPELPSVTREKLVQQYGMLLEHSFTLLNEVGLLEFFQNVIKETRAEPK
Sbjct: 361 QQVINIDQIRETLPELPSVTREKLVQQYGMLLEHSFTLLNEVGLLEFFQNVIKETRAEPK 420

Query: 421 KVTSWVLNTFLGYLKQQNLAVSESPVTPSALAELLDLLDSRTISSSAAKQVFEELWKREG 480
           KVTSWVLNTFLGYLKQQNLAVSESPVTPSALAELLDLLDSRTISSSAAKQVFEELWKREG
Sbjct: 421 KVTSWVLNTFLGYLKQQNLAVSESPVTPSALAELLDLLDSRTISSSAAKQVFEELWKREG 480

Query: 481 KTPGQIVSEKQLELMQDQGALEQLCHSVMEAHPQVVMDVKNRNPRAINKLIGLVRKATQS 540
           KTPGQIVSEKQLELMQDQGALEQLCHSVMEAHPQVVMDVKNRNPRAINKLIGLVRKATQS
Sbjct: 481 KTPGQIVSEKQLELMQDQGALEQLCHSVMEAHPQVVMDVKNRNPRAINKLIGLVRKATQS 540

Query: 541 RADPVMIKEILEKKLSL 557
           RADPVMIKEILEKKLSL
Sbjct: 541 RADPVMIKEILEKKLSL 557


>gi|11545912 nucleotide-binding oligomerization domain containing 2
           [Homo sapiens]
          Length = 1040

 Score = 32.0 bits (71), Expect = 1.5
 Identities = 39/136 (28%), Positives = 62/136 (45%), Gaps = 13/136 (9%)

Query: 377 PSVTREKLVQQYGMLLEH-SFTLLNEVGLLEF-FQNVIKETRAEPKKVTSWVLNTFLGYL 434
           P V +E + Q   +LL+H    LL   G  EF F+   +E    P   TS  + T L  L
Sbjct: 356 PDVGQEDIFQ---LLLDHPDRVLLTFDGFDEFKFRFTDRERHCSPTDPTS--VQTLLFNL 410

Query: 435 KQQNLAVSESPVT---PSALAELL-DLLDSRTISSSAAKQVFEELWKREGKTPGQIVSEK 490
            Q NL  +   V    P+A++  L   + +       ++Q  E   ++    PG  V+++
Sbjct: 411 LQGNLLKNARKVVTSRPAAVSAFLRKYIRTEFNLKGFSEQGIELYLRKRHHEPG--VADR 468

Query: 491 QLELMQDQGALEQLCH 506
            + L+Q+  AL  LCH
Sbjct: 469 LIRLLQETSALHGLCH 484


>gi|31581534 tRNA isopentenyltransferase 1 [Homo sapiens]
          Length = 467

 Score = 31.2 bits (69), Expect = 2.6
 Identities = 40/194 (20%), Positives = 75/194 (38%), Gaps = 40/194 (20%)

Query: 154 QQRLPIAVNG------SLIYGVCAGKKQSQVIPKTVRIKQIQLEQDSGKSLHDNLRSQTL 207
           + ++PI V G      SL++ V    K  ++  + V  ++++LE++ G  LH  L     
Sbjct: 112 RDKIPIVVGGTNYYIESLLWKVLVNTKPQEMGTEKVIDRKVELEKEDGLVLHKRLSQ--- 168

Query: 208 IDLNRAGVGLLEVVLEPDMSC---GEEAATAVRELQLILQALGTSQANMAEGQLRVDANI 264
                         ++P+M+      +     R LQ + +  G S +     Q       
Sbjct: 169 --------------VDPEMAAKLHPHDKRKVARSLQ-VFEETGISHSEFLHRQ------- 206

Query: 265 SVHHPGEPLGVRTEVKNLNSIRFLA--KAIDYEIQRQINELENGGEILNETRSFHHKLGC 322
                G PLG   +  N   +   A    +D  + ++++++   G +L E R FH +   
Sbjct: 207 HTEEGGGPLGGPLKFSNPCILWLHADQAVLDERLDKRVDDMLAAG-LLEELRDFHRRYN- 264

Query: 323 TMSMRDKEGKQDYR 336
                  E  QDY+
Sbjct: 265 --QKNVSENSQDYQ 276


>gi|157266317 ataxia telangiectasia and Rad3 related protein [Homo
            sapiens]
          Length = 2644

 Score = 30.0 bits (66), Expect = 5.8
 Identities = 26/96 (27%), Positives = 39/96 (40%), Gaps = 5/96 (5%)

Query: 48   QPLHTAQKTRKGEHKWAAVVGLEIHAQISSNSKLFSGSQVRFSAPPNSLVSFFDASLPGT 107
            Q LH     R GEH      GL I A  +S+   + G +   S  P  +  +    L G 
Sbjct: 1073 QGLHNELLLRIGEHYQQVFNGLSILASFASSDDPYQGPRDIIS--PELMADYLQPKLLGI 1130

Query: 108  LPVLNRRCVEAAV---MTGLALNCHINKKSLFDRKH 140
            L   N + + ++V      +ALN  ++   L   KH
Sbjct: 1131 LAFFNMQLLSSSVGIEDKKMALNSLMSLMKLMGPKH 1166


>gi|169218238 PREDICTED: similar to ataxia telangiectasia and Rad3
           related protein, partial [Homo sapiens]
          Length = 2105

 Score = 30.0 bits (66), Expect = 5.8
 Identities = 26/96 (27%), Positives = 39/96 (40%), Gaps = 5/96 (5%)

Query: 48  QPLHTAQKTRKGEHKWAAVVGLEIHAQISSNSKLFSGSQVRFSAPPNSLVSFFDASLPGT 107
           Q LH     R GEH      GL I A  +S+   + G +   S  P  +  +    L G 
Sbjct: 831 QGLHNELLLRIGEHYQQVFNGLSILASFASSDDPYQGPRDIIS--PELMADYLQPKLLGI 888

Query: 108 LPVLNRRCVEAAV---MTGLALNCHINKKSLFDRKH 140
           L   N + + ++V      +ALN  ++   L   KH
Sbjct: 889 LAFFNMQLLSSSVGIEDKKMALNSLMSLMKLMGPKH 924


>gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo
           sapiens]
          Length = 1227

 Score = 30.0 bits (66), Expect = 5.8
 Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 8/95 (8%)

Query: 461 RTISSSAAKQVFEELWKREGKTPGQIV------SEKQLELMQDQGAL--EQLCHSVMEAH 512
           R  + S AK+V EE+    G+  G  +      SE  L      G L  E L  + ++ +
Sbjct: 587 RVAAMSVAKRVSEEMGGNLGEEVGYAIRFEDCTSENTLIKYMTDGILLRESLREADLDHY 646

Query: 513 PQVVMDVKNRNPRAINKLIGLVRKATQSRADPVMI 547
             ++MD  +      + L GL+R+    R+D  +I
Sbjct: 647 SAIIMDEAHERSLNTDVLFGLLREVVARRSDLKLI 681


>gi|20127519 TPX2, microtubule-associated protein homolog [Homo
           sapiens]
          Length = 747

 Score = 29.6 bits (65), Expect = 7.6
 Identities = 29/132 (21%), Positives = 54/132 (40%), Gaps = 15/132 (11%)

Query: 293 DYEIQRQINELENGGEILNETRSFHHKLGCTMSMRDKEGKQDYRFMP--EPNLPPLVLYD 350
           D EI+++I E E+  +  +E   FH +   T  + D  G  + + +P   P  P   L +
Sbjct: 434 DLEIEKRIQERESKKKTEDEHFEFHSRPCPTKILEDVVGVPEKKVLPITVPKSPAFALKN 493

Query: 351 ATSLPAGADPQQVINIDQIRETLPELPSVTREKLVQQYGMLLEHSFTLLNEVGLLEF-FQ 409
              +P   D ++            + P V + + V  YG+  +        V +  F F 
Sbjct: 494 RIRMPTKEDEEE------------DEPVVIKAQPVPHYGVPFKPQIPEARTVEICPFSFD 541

Query: 410 NVIKETRAEPKK 421
           +  KE + + +K
Sbjct: 542 SRDKERQLQKEK 553


>gi|157909822 pragmin [Homo sapiens]
          Length = 1402

 Score = 29.6 bits (65), Expect = 7.6
 Identities = 33/127 (25%), Positives = 52/127 (40%), Gaps = 16/127 (12%)

Query: 271  EPLGVRTEVKNLNSIRFLAKAIDYEIQRQINELENG---GEILNETRSFHHKLGCTMSMR 327
            +P G     +  +  R   + +     R+ +E + G    E+L++   F         +R
Sbjct: 1219 KPGGTPNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIYELLHQPNPFE--------VR 1270

Query: 328  DKEGKQDYRFMPEPNLPPLVLYDA-----TSLPAGADPQQVINIDQIRETLPELPSVTRE 382
             +  ++DYR    P LP L LY         L   ADP + I I + +  L  L    R 
Sbjct: 1271 AQLRERDYRQEDLPPLPALSLYSPGLQQLAHLLLEADPIKRIRIGEAKRVLQCLLWGPRR 1330

Query: 383  KLVQQYG 389
            +LVQQ G
Sbjct: 1331 ELVQQPG 1337


>gi|23397678 signal transducer and activator of transcription 6
           [Homo sapiens]
          Length = 847

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 41/177 (23%), Positives = 73/177 (41%), Gaps = 24/177 (13%)

Query: 389 GMLLEHSF--TLLNEVGLLEFFQNVIKETRAEPKKVTSWVLNTFLGYLKQQNLAVSESPV 446
           G +  HS   T  N  G  E    +++ET  E +   + VL     + +QQ LA + +P 
Sbjct: 158 GQVSLHSLIETPANGTGPSEALAMLLQETTGELEAAKALVLKRIQIWKRQQQLAGNGAPF 217

Query: 447 TPSALAELLDLLDSRTISSSAAKQVFEELWKREGKTPGQIVSEKQLELMQDQGALEQLCH 506
             S LA L +  +S          ++ +L +  G   G++  + +  L    G L+++  
Sbjct: 218 EES-LAPLQERCESLV-------DIYSQLQQEVGAAGGELEPKTRASL---TGRLDEVLR 266

Query: 507 S------VMEAHPQVVMDVKNRNPRAINKLIGL-----VRKATQSRADPVMIKEILE 552
           +      ++E  P  V+  + +    +  L+GL       K    RAD V  K+  E
Sbjct: 267 TLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLRFLGAPAKPPLVRADMVTEKQARE 323


>gi|21536423 amphiphysin isoform 2 [Homo sapiens]
          Length = 653

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 2/82 (2%)

Query: 339 PEPNLPPLVLYDATSLPAGADPQQVINIDQIRE--TLPELPSVTREKLVQQYGMLLEHSF 396
           P P   P    + T  PA   P +  +  Q R+   +P LP VT  K +QQ  ++     
Sbjct: 267 PSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFED 326

Query: 397 TLLNEVGLLEFFQNVIKETRAE 418
             + E+ +    QN + E + E
Sbjct: 327 NFVPEISVTTPSQNEVPEVKKE 348


>gi|4502081 amphiphysin isoform 1 [Homo sapiens]
          Length = 695

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 2/82 (2%)

Query: 339 PEPNLPPLVLYDATSLPAGADPQQVINIDQIRE--TLPELPSVTREKLVQQYGMLLEHSF 396
           P P   P    + T  PA   P +  +  Q R+   +P LP VT  K +QQ  ++     
Sbjct: 267 PSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFED 326

Query: 397 TLLNEVGLLEFFQNVIKETRAE 418
             + E+ +    QN + E + E
Sbjct: 327 NFVPEISVTTPSQNEVPEVKKE 348


>gi|82659109 retinoblastoma-associated factor 600 [Homo sapiens]
          Length = 5183

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 21/81 (25%), Positives = 35/81 (43%), Gaps = 3/81 (3%)

Query: 392  LEHSFTLLNEVGLLEFFQNVIKETRAEPKKVTSWVLNTFLGYLKQQNLAVSESPVTPSAL 451
            L+  + L +  GLL  F  V    R    ++   VLN   GYL  + L V  + +     
Sbjct: 4232 LQQGYALKSLTGLLSSFVEVESIKRHFKSRLVGTVLN---GYLCLRKLVVQRTKLIDETQ 4288

Query: 452  AELLDLLDSRTISSSAAKQVF 472
              LL++L+  T  + +  + F
Sbjct: 4289 DMLLEMLEDMTTGTESETKAF 4309


>gi|50083293 coiled-coil domain containing 123 [Homo sapiens]
          Length = 783

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 51/251 (20%), Positives = 97/251 (38%), Gaps = 22/251 (8%)

Query: 308 EILNETRSFHHKLGCTMSMRDKEGKQDYRFMPEPNLPPLVLYDATSLPAGADPQQVINID 367
           E++ E    H +L  + ++  +E +Q            LVL +   L    + QQ    D
Sbjct: 400 EVVKENEELHQELNKSSAVTSEEWRQ------LQTQAKLVLEENKLLLEQLEIQQRKAKD 453

Query: 368 QIRETLPELPSVTREKLVQQ---YGMLLEHSFTLLNEVGLLEFFQNVIKETRAEPK-KVT 423
             +E L E+  +T++ ++ +   +G   E    L      LE  +   +E +     K+ 
Sbjct: 454 SHQERLQEVSKLTKQLMLLEAKTHGQEKE----LAENREQLEILRAKCQELKTHSDGKIA 509

Query: 424 SWVLNTFLGYLKQQNLAVSESPVTPSALAELLDLLDSRTISSSAAKQVFEELWKREGKTP 483
             V  + +  LK Q     E        AE+ +L++  T+  +  K +   L ++   T 
Sbjct: 510 VEVHKSIVNELKSQLQKEEEKE-----RAEMEELMEKLTVLQAQKKSL---LLEKNSLTE 561

Query: 484 GQIVSEKQLELMQDQGALEQLCHSVMEAHPQVVMDVKNRNPRAINKLIGLVRKATQSRAD 543
                E +LE  Q      Q    V++   +  M  +    + +  L+GL    TQ R  
Sbjct: 562 QNKALEAELERAQKINRKSQKKIEVLKKQVEKAMGNEMSAHQYLANLVGLAENITQERDS 621

Query: 544 PVMIKEILEKK 554
            + + + LE +
Sbjct: 622 LMCLAKCLESE 632


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,214,501
Number of Sequences: 37866
Number of extensions: 877900
Number of successful extensions: 2491
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2488
Number of HSP's gapped (non-prelim): 17
length of query: 557
length of database: 18,247,518
effective HSP length: 107
effective length of query: 450
effective length of database: 14,195,856
effective search space: 6388135200
effective search space used: 6388135200
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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