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Search of human proteins with 4758762
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758762 asparaginyl-tRNA synthetase [Homo sapiens]
(548 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758762 asparaginyl-tRNA synthetase [Homo sapiens] 1132 0.0
gi|226491502 asparaginyl-tRNA synthetase 2, mitochondrial [Homo ... 181 2e-45
gi|45439306 aspartyl-tRNA synthetase [Homo sapiens] 149 5e-36
gi|40789249 aspartyl-tRNA synthetase 2, mitochondrial [Homo sapi... 57 3e-08
gi|194272210 lysyl-tRNA synthetase isoform 1 [Homo sapiens] 44 3e-04
gi|5031815 lysyl-tRNA synthetase isoform 2 [Homo sapiens] 44 3e-04
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 36 0.080
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 35 0.14
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 35 0.14
gi|5032041 Ras homolog enriched in brain [Homo sapiens] 34 0.30
gi|72534692 5'-nucleotidase domain containing 3 [Homo sapiens] 34 0.30
gi|19923899 coiled-coil domain containing 45 [Homo sapiens] 34 0.40
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 33 0.67
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 33 0.67
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is... 33 0.67
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 33 0.67
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 33 0.67
gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens] 33 0.88
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 33 0.88
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 33 0.88
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 33 0.88
gi|167466219 dpy-19-like 4 [Homo sapiens] 33 0.88
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof... 33 0.88
gi|120953243 leucine-rich repeats and IQ motif containing 1 isof... 33 0.88
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 32 1.1
gi|4503179 oral-facial-digital syndrome 1 [Homo sapiens] 32 1.1
gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo ... 32 1.5
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 32 1.5
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho... 32 1.5
gi|75677576 dyslexia susceptibility 1 candidate 1 isoform c [Hom... 32 1.5
>gi|4758762 asparaginyl-tRNA synthetase [Homo sapiens]
Length = 548
Score = 1132 bits (2928), Expect = 0.0
Identities = 548/548 (100%), Positives = 548/548 (100%)
Query: 1 MVLAELYVSDREGSDATGDGTKEKPFKTGLKALMTVGKEPFPTIYVDSQKENERWNVISK 60
MVLAELYVSDREGSDATGDGTKEKPFKTGLKALMTVGKEPFPTIYVDSQKENERWNVISK
Sbjct: 1 MVLAELYVSDREGSDATGDGTKEKPFKTGLKALMTVGKEPFPTIYVDSQKENERWNVISK 60
Query: 61 SQLKNIKKMWHREQMKSESREKKEAEDSLRREKNLEEAKKITIKNDPSLPEPKCVKIGAL 120
SQLKNIKKMWHREQMKSESREKKEAEDSLRREKNLEEAKKITIKNDPSLPEPKCVKIGAL
Sbjct: 61 SQLKNIKKMWHREQMKSESREKKEAEDSLRREKNLEEAKKITIKNDPSLPEPKCVKIGAL 120
Query: 121 EGYRGQRVKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLADELCQCYNGVLLSTESSVA 180
EGYRGQRVKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLADELCQCYNGVLLSTESSVA
Sbjct: 121 EGYRGQRVKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLADELCQCYNGVLLSTESSVA 180
Query: 181 VYGMLNLTPKGKQAPGGHELSCDFWELIGLAPAGGADNLINEESDVDVQLNNRHMMIRGE 240
VYGMLNLTPKGKQAPGGHELSCDFWELIGLAPAGGADNLINEESDVDVQLNNRHMMIRGE
Sbjct: 181 VYGMLNLTPKGKQAPGGHELSCDFWELIGLAPAGGADNLINEESDVDVQLNNRHMMIRGE 240
Query: 241 NMSKILKARSMVTRCFRDHFFDRGYYEVTPPTLVQTQVEGGATLFKLDYFGEEAFLTQSS 300
NMSKILKARSMVTRCFRDHFFDRGYYEVTPPTLVQTQVEGGATLFKLDYFGEEAFLTQSS
Sbjct: 241 NMSKILKARSMVTRCFRDHFFDRGYYEVTPPTLVQTQVEGGATLFKLDYFGEEAFLTQSS 300
Query: 301 QLYLETCLPALGDVFCIAQSYRAEQSRTRRHLAEYTHVEAECPFLTFDDLLNRLEDLVCD 360
QLYLETCLPALGDVFCIAQSYRAEQSRTRRHLAEYTHVEAECPFLTFDDLLNRLEDLVCD
Sbjct: 301 QLYLETCLPALGDVFCIAQSYRAEQSRTRRHLAEYTHVEAECPFLTFDDLLNRLEDLVCD 360
Query: 361 VVDRILKSPAGSIVHELNPNFQPPKRPFKRMNYSDAIVWLKEHDVKKEDGTFYEFGEDIP 420
VVDRILKSPAGSIVHELNPNFQPPKRPFKRMNYSDAIVWLKEHDVKKEDGTFYEFGEDIP
Sbjct: 361 VVDRILKSPAGSIVHELNPNFQPPKRPFKRMNYSDAIVWLKEHDVKKEDGTFYEFGEDIP 420
Query: 421 EAPERLMTDTINEPILLCRFPVEIKSFYMQRCPEDSRLTESVDVLMPNVGEIVGGSMRIF 480
EAPERLMTDTINEPILLCRFPVEIKSFYMQRCPEDSRLTESVDVLMPNVGEIVGGSMRIF
Sbjct: 421 EAPERLMTDTINEPILLCRFPVEIKSFYMQRCPEDSRLTESVDVLMPNVGEIVGGSMRIF 480
Query: 481 DSEEILAGYKREGIDPTPYYWYTDQRKYGTCPHGGYGLGLERFLTWILNRYHIRDVCLYP 540
DSEEILAGYKREGIDPTPYYWYTDQRKYGTCPHGGYGLGLERFLTWILNRYHIRDVCLYP
Sbjct: 481 DSEEILAGYKREGIDPTPYYWYTDQRKYGTCPHGGYGLGLERFLTWILNRYHIRDVCLYP 540
Query: 541 RFVQRCTP 548
RFVQRCTP
Sbjct: 541 RFVQRCTP 548
>gi|226491502 asparaginyl-tRNA synthetase 2, mitochondrial [Homo
sapiens]
Length = 477
Score = 181 bits (459), Expect = 2e-45
Identities = 140/449 (31%), Positives = 216/449 (48%), Gaps = 41/449 (9%)
Query: 125 GQRVKVFGWVHRLRRQGKNLMFLVLRDGTGY--LQCVLADELCQCYNGVLLSTESSVAVY 182
G+R+K+ GW+ +R Q K ++FL + DG+ LQ V L + L+ SSV V
Sbjct: 41 GERIKIQGWIRSVRSQ-KEVLFLHVNDGSSLESLQVVADSGL----DSRELNFGSSVEVQ 95
Query: 183 GMLNLTPKGKQAPGGHELSCDFWELIGLAPAGGADNLINEESDVDVQLNNRHMMIRGENM 242
G L +P +Q EL + ++IG A E ++ H R +
Sbjct: 96 GQLIKSPSKRQ---NVELKAEKIKVIGNCDAKDFPIKYKERHPLEYLRQYPHFRCRTNVL 152
Query: 243 SKILKARSMVTRCFRDHFFDRGYYEVTPPTLVQTQVEGGATLFKLD-----------YFG 291
IL+ RS T F D G+ + P + EG LF+L+ +F
Sbjct: 153 GSILRIRSEATAAIHSFFKDSGFVHIHTPIITSNDSEGAGELFQLEPSGKLKVPEENFFN 212
Query: 292 EEAFLTQSSQLYLETCLPALGDVFCIAQSYRAEQSRTRRHLAEYTHVEAECPFL-TFDDL 350
AFLT S QL+LE A VF ++RAE S++RRHLAE+ +EAE F+ + DL
Sbjct: 213 VPAFLTVSGQLHLEVMSGAFTQVFTFGPTFRAENSQSRRHLAEFYMIEAEISFVDSLQDL 272
Query: 351 LNRLEDLVCDVVDRILKSPAGSIVHELNPNFQPP----------KRPFKRMNYSDAIVWL 400
+ +E+L +L + EL F P K F ++Y++A+ L
Sbjct: 273 MQVIEELFKATTMMVLSKCPEDV--ELCHKFIAPGQKDRLEHMLKNNFLIISYTEAVEIL 330
Query: 401 KEHDVKKEDGTFY-EFGEDIPEAPER-LMTDTINEPILLCRFPVEIKSFYMQRCPEDSRL 458
K+ ++ TF E+G D+ E+ L+ N P+ + +P+ +K FYM+ + +
Sbjct: 331 KQ---ASQNFTFTPEWGADLRTEHEKYLVKHCGNIPVFVINYPLTLKPFYMRDNEDGPQH 387
Query: 459 T-ESVDVLMPNVGEIVGGSMRIFDSEEILAGYKREGIDPTPYYWYTDQRKYGTCPHGGYG 517
T +VD+L+P VGE+ GG +R + R G+ Y WY D R++G+ PHGG+G
Sbjct: 388 TVAAVDLLVPGVGELFGGGLREERYHFLEERLARSGLTEV-YQWYLDLRRFGSVPHGGFG 446
Query: 518 LGLERFLTWILNRYHIRDVCLYPRFVQRC 546
+G ER+L IL +I+DV +PRF C
Sbjct: 447 MGFERYLQCILGVDNIKDVIPFPRFPHSC 475
>gi|45439306 aspartyl-tRNA synthetase [Homo sapiens]
Length = 501
Score = 149 bits (377), Expect = 5e-36
Identities = 97/335 (28%), Positives = 163/335 (48%), Gaps = 23/335 (6%)
Query: 227 DVQLNNRHMMIRGENMSKILKARSMVTRCFRDHFFDRGYYEVTPPTLVQTQVEGGATLFK 286
D +L+NR + +R + + +S + FR+ ++G+ E+ P ++ EGGA +F
Sbjct: 177 DTRLDNRVIDLRTSTSQAVFRLQSGICHLFRETLINKGFVEIQTPKIISAASEGGANVFT 236
Query: 287 LDYFGEEAFLTQSSQLYLETCLPA-LGDVFCIAQSYRAEQSRTRRHLAEYTHVEAECPFL 345
+ YF A+L QS QLY + C+ A VF I +RAE S T RHL E+ ++ E +
Sbjct: 237 VSYFKNNAYLAQSPQLYKQMCICADFEKVFSIGPVFRAEDSNTHRHLTEFVGLDIE---M 293
Query: 346 TFDDLLNRLEDLVCDVVDRILKSPAGSIVHELNP-NFQPPKRPFK------RMNYSDAIV 398
F+ + + + + D + +I K E+ N Q P PFK R+ Y +A+
Sbjct: 294 AFNYHYHEVMEEIADTMVQIFKGLQERFQTEIQTVNKQFPCEPFKFLEPTLRLEYCEALA 353
Query: 399 WLKEHDVKKEDGTFYEFGEDIPEAPERLMTDTINEP-----ILLCRFPVEIKSFYMQRCP 453
L+E V+ D +D+ E+L+ + E +L ++P+ ++ FY P
Sbjct: 354 MLREAGVEMGD------EDDLSTPNEKLLGHLVKEKYDTDFYILDKYPLAVRPFYTMPDP 407
Query: 454 EDSRLTESVDVLMPNVGEIVGGSMRIFDSEEILAGYKREGIDPTPYYWYTDQRKYGTCPH 513
+ + + S D+ M EI+ G+ RI D + + GID Y D ++G PH
Sbjct: 408 RNPKQSNSYDMFMRG-EEILSGAQRIHDPQLLTERALHHGIDLEKIKAYIDSFRFGAPPH 466
Query: 514 GGYGLGLERFLTWILNRYHIRDVCLYPRFVQRCTP 548
G G+GLER L +++R ++PR +R TP
Sbjct: 467 AGGGIGLERVTMLFLGLHNVRQTSMFPRDPKRLTP 501
>gi|40789249 aspartyl-tRNA synthetase 2, mitochondrial [Homo
sapiens]
Length = 645
Score = 57.4 bits (137), Expect = 3e-08
Identities = 67/245 (27%), Positives = 111/245 (45%), Gaps = 17/245 (6%)
Query: 125 GQRVKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVL-ADELCQCYNGVLLS--TESSVAV 181
GQ V + GW+ + RRQ FLVLRD G +Q ++ DE +L ES V V
Sbjct: 63 GQEVTLCGWI-QYRRQNT---FLVLRDFDGLVQVIIPQDESAASVKKILCEAPVESVVQV 118
Query: 182 YGMLNLTPKGKQAP----GGHELSCDFWELIGLAPAGGADNLINEESDVDVQLNNRHMMI 237
G + P G++ P G E+ EL+ + + ++L R++ +
Sbjct: 119 SGTVISRPAGQENPKMPTGEIEIKVKTAELLNACKKLPFEIKNFVKKTEALRLQYRYLDL 178
Query: 238 RGENMSKILKARSMVTRCFRDHFFD-RGYYEVTPPTLVQTQVEGGATLFKLDYF--GEEA 294
R M L+ RS + R++ + G+ ++ PTL + + GGA F + G+
Sbjct: 179 RSFQMQYNLRLRSQMVMKMREYLCNLHGFVDIETPTLFK-RTPGGAKEFLVPSREPGKFY 237
Query: 295 FLTQSSQLYLETCL-PALGDVFCIAQSYRAEQSRTRRHLAEYTHVEAECPFLTFDDLLNR 353
L QS Q + + + L F +A+ YR E SR R E+T ++ E F+ + +
Sbjct: 238 SLPQSPQQFKQLLMVGGLDRYFQVARCYRDEGSRPDRQ-PEFTQIDIEMSFVDQTGIQSL 296
Query: 354 LEDLV 358
+E L+
Sbjct: 297 IEGLL 301
Score = 44.7 bits (104), Expect = 2e-04
Identities = 34/104 (32%), Positives = 54/104 (51%), Gaps = 9/104 (8%)
Query: 441 PVEIKSFYMQRCPEDSRLTESVDVLMPNVGEIVGGSMRIFDSE---EILAGYKREGIDPT 497
P +I Y + P+ +R ++ D+++ N EI GGS+RI ++E ILA +E +
Sbjct: 509 PSDIHLLYTE--PKKAR-SQHYDLVL-NGNEIGGGSIRIHNAELQRYILATLLKEDVKML 564
Query: 498 PYYWYTDQRKYGTCPHGGYGLGLERFLTWILNRYHIRDVCLYPR 541
+ YG PHGG LGL+R + + IRDV +P+
Sbjct: 565 SHL--LQALDYGAPPHGGIALGLDRLICLVTGSPSIRDVIAFPK 606
>gi|194272210 lysyl-tRNA synthetase isoform 1 [Homo sapiens]
Length = 625
Score = 44.3 bits (103), Expect = 3e-04
Identities = 104/465 (22%), Positives = 177/465 (38%), Gaps = 71/465 (15%)
Query: 128 VKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLA--------DELCQCYNGVLLSTESSV 179
+KV G +H R G L+F LR G G V+A +E N L +
Sbjct: 154 LKVAGRIHAKRASGGKLIFYDLR-GEGVKLQVMANSRNYKSEEEFIHINNK--LRRGDII 210
Query: 180 AVYGMLNLTPKGKQAPGGHELSCDFWELIGLAPA-GGADNLINEESDVDVQLNNRHM-MI 237
V G T KG ELS +E+ L+P +L D + + R++ +I
Sbjct: 211 GVQGNPGKTKKG-------ELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLI 263
Query: 238 RGENMSKILKARSMVTRCFRDHFFDRGYYEVTPPTLVQTQVEGGATLFKLDYFGEEA--- 294
+ + + RS + R + G+ E+ P + + GGA + E
Sbjct: 264 LNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMM--NIIPGGAVAKPFITYHNELDMN 321
Query: 295 -FLTQSSQLYLETCLPA-LGDVFCIAQSYRAEQSRTRRHLAEYTHVEAECPFLTFDDLLN 352
++ + +LY + + + V+ I + +R E H E+T E + + DL+
Sbjct: 322 LYMRIAPELYHKMLVVGGIDRVYEIGRQFRNE-GIDLTHNPEFTTCEFYMAYADYHDLME 380
Query: 353 RLEDLVCDVVDRILKS------PAGSIVHELNPNFQPPKRPFKRMNYSDAIVWLKEHDVK 406
E +V +V I S P G + +F P PF+R+N + + K +K
Sbjct: 381 ITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFTP---PFRRINMVEELE--KALGMK 435
Query: 407 KEDGTFYEFGE------DI----------PEAPERLMTDTINE--------PILLCRFPV 442
+ +E E DI P RL+ + E P +C P
Sbjct: 436 LPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHP- 494
Query: 443 EIKSFYMQRCPEDSRLTESVDVLMP-----NVGEIVGGSMRIFDSEEILAGYKREGIDPT 497
+I S + LTE ++ + N + MR E A K G D
Sbjct: 495 QIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEA 554
Query: 498 PYY--WYTDQRKYGTCPHGGYGLGLERFLTWILNRYHIRDVCLYP 540
+ + +YG P G+G+G++R ++ + +I++V L+P
Sbjct: 555 MFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFP 599
>gi|5031815 lysyl-tRNA synthetase isoform 2 [Homo sapiens]
Length = 597
Score = 44.3 bits (103), Expect = 3e-04
Identities = 104/465 (22%), Positives = 177/465 (38%), Gaps = 71/465 (15%)
Query: 128 VKVFGWVHRLRRQGKNLMFLVLRDGTGYLQCVLA--------DELCQCYNGVLLSTESSV 179
+KV G +H R G L+F LR G G V+A +E N L +
Sbjct: 126 LKVAGRIHAKRASGGKLIFYDLR-GEGVKLQVMANSRNYKSEEEFIHINNK--LRRGDII 182
Query: 180 AVYGMLNLTPKGKQAPGGHELSCDFWELIGLAPA-GGADNLINEESDVDVQLNNRHM-MI 237
V G T KG ELS +E+ L+P +L D + + R++ +I
Sbjct: 183 GVQGNPGKTKKG-------ELSIIPYEITLLSPCLHMLPHLHFGLKDKETRYRQRYLDLI 235
Query: 238 RGENMSKILKARSMVTRCFRDHFFDRGYYEVTPPTLVQTQVEGGATLFKLDYFGEEA--- 294
+ + + RS + R + G+ E+ P + + GGA + E
Sbjct: 236 LNDFVRQKFIIRSKIITYIRSFLDELGFLEIETPMM--NIIPGGAVAKPFITYHNELDMN 293
Query: 295 -FLTQSSQLYLETCLPA-LGDVFCIAQSYRAEQSRTRRHLAEYTHVEAECPFLTFDDLLN 352
++ + +LY + + + V+ I + +R E H E+T E + + DL+
Sbjct: 294 LYMRIAPELYHKMLVVGGIDRVYEIGRQFRNE-GIDLTHNPEFTTCEFYMAYADYHDLME 352
Query: 353 RLEDLVCDVVDRILKS------PAGSIVHELNPNFQPPKRPFKRMNYSDAIVWLKEHDVK 406
E +V +V I S P G + +F P PF+R+N + + K +K
Sbjct: 353 ITEKMVSGMVKHITGSYKVTYHPDGPEGQAYDVDFTP---PFRRINMVEELE--KALGMK 407
Query: 407 KEDGTFYEFGE------DI----------PEAPERLMTDTINE--------PILLCRFPV 442
+ +E E DI P RL+ + E P +C P
Sbjct: 408 LPETNLFETEETRKILDDICVAKAVECPPPRTTARLLDKLVGEFLEVTCINPTFICDHP- 466
Query: 443 EIKSFYMQRCPEDSRLTESVDVLMP-----NVGEIVGGSMRIFDSEEILAGYKREGIDPT 497
+I S + LTE ++ + N + MR E A K G D
Sbjct: 467 QIMSPLAKWHRSKEGLTERFELFVMKKEICNAYTELNDPMRQRQLFEEQAKAKAAGDDEA 526
Query: 498 PYY--WYTDQRKYGTCPHGGYGLGLERFLTWILNRYHIRDVCLYP 540
+ + +YG P G+G+G++R ++ + +I++V L+P
Sbjct: 527 MFIDENFCTALEYGLPPTAGWGMGIDRVAMFLTDSNNIKEVLLFP 571
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 36.2 bits (82), Expect = 0.080
Identities = 24/89 (26%), Positives = 44/89 (49%), Gaps = 11/89 (12%)
Query: 50 KENERWNVISKSQLKNIKKMWHREQMKSESREK--------KEAEDSLRREKNLEEAKKI 101
+ENE WN +++ Q +KMW +E+ E EK +E E+ +RR++ + K+
Sbjct: 274 EENELWNRLNQQQ---EEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEE 330
Query: 102 TIKNDPSLPEPKCVKIGALEGYRGQRVKV 130
++ + K KI LE ++ K+
Sbjct: 331 KMRRQEEMMWEKEEKIRELEEKMHEQEKI 359
Score = 30.0 bits (66), Expect = 5.7
Identities = 19/80 (23%), Positives = 39/80 (48%), Gaps = 2/80 (2%)
Query: 67 KKMWHREQMKSESREK-KEAEDSLRREKNLEEAKKITIKNDPSLPEPKCVKIGALEGYR- 124
+KMW +E+ E EK + E+ +R ++ ++ I+ + + + K+G EG
Sbjct: 418 EKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMC 477
Query: 125 GQRVKVFGWVHRLRRQGKNL 144
Q K+ ++RRQ + +
Sbjct: 478 EQEAKMQEQEEKMRRQEEKI 497
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 35.4 bits (80), Expect = 0.14
Identities = 28/105 (26%), Positives = 52/105 (49%), Gaps = 14/105 (13%)
Query: 50 KENERWNVISKSQLKNIKKMWHREQMKSESREK--------KEAEDSLRR--EKNLEEAK 99
+ENE WN++++ Q +KMW +E+ E EK +E E+ + R EK E+ +
Sbjct: 283 EENELWNLLNQQQ---EEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEE 339
Query: 100 KITIKNDPSLPEPKCVKIGALEGYRGQRVKVFGWVHRLRRQGKNL 144
KI + D + + ++ E R Q K++ ++R Q + +
Sbjct: 340 KIREQEDKMWRQEEKIR-EQEEKIREQEEKMWRQEEKIREQDEKI 383
Score = 30.8 bits (68), Expect = 3.3
Identities = 18/68 (26%), Positives = 35/68 (51%), Gaps = 5/68 (7%)
Query: 49 QKENERWNV---ISKSQLKNIKKMWHREQMKSESREK--KEAEDSLRREKNLEEAKKITI 103
++E E W I + + K +KMW +E+ E EK ++ E+ R+E+ + E +++
Sbjct: 385 EQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444
Query: 104 KNDPSLPE 111
+ L E
Sbjct: 445 DQEEKLRE 452
Score = 30.0 bits (66), Expect = 5.7
Identities = 18/74 (24%), Positives = 38/74 (51%), Gaps = 4/74 (5%)
Query: 67 KKMWHREQMKSESREK-KEAEDSLRREKNLEEAKKITIKNDPSLPEPKCVKIGALE---G 122
+KMW +E+ E EK +E E+ ++R++ +++ + + + V++ LE G
Sbjct: 503 EKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLG 562
Query: 123 YRGQRVKVFGWVHR 136
GQ+ ++ G R
Sbjct: 563 KLGQKAELLGGAGR 576
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 35.4 bits (80), Expect = 0.14
Identities = 28/105 (26%), Positives = 52/105 (49%), Gaps = 14/105 (13%)
Query: 50 KENERWNVISKSQLKNIKKMWHREQMKSESREK--------KEAEDSLRR--EKNLEEAK 99
+ENE WN++++ Q +KMW +E+ E EK +E E+ + R EK E+ +
Sbjct: 283 EENELWNLLNQQQ---EEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEE 339
Query: 100 KITIKNDPSLPEPKCVKIGALEGYRGQRVKVFGWVHRLRRQGKNL 144
KI + D + + ++ E R Q K++ ++R Q + +
Sbjct: 340 KIREQEDKMWRQEEKIR-EQEEKIREQEEKMWRQEEKIREQDEKI 383
Score = 30.8 bits (68), Expect = 3.3
Identities = 18/68 (26%), Positives = 35/68 (51%), Gaps = 5/68 (7%)
Query: 49 QKENERWNV---ISKSQLKNIKKMWHREQMKSESREK--KEAEDSLRREKNLEEAKKITI 103
++E E W I + + K +KMW +E+ E EK ++ E+ R+E+ + E +++
Sbjct: 385 EQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQ 444
Query: 104 KNDPSLPE 111
+ L E
Sbjct: 445 DQEEKLRE 452
Score = 30.0 bits (66), Expect = 5.7
Identities = 18/74 (24%), Positives = 38/74 (51%), Gaps = 4/74 (5%)
Query: 67 KKMWHREQMKSESREK-KEAEDSLRREKNLEEAKKITIKNDPSLPEPKCVKIGALE---G 122
+KMW +E+ E EK +E E+ ++R++ +++ + + + V++ LE G
Sbjct: 503 EKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLG 562
Query: 123 YRGQRVKVFGWVHR 136
GQ+ ++ G R
Sbjct: 563 KLGQKAELLGGAGR 576
>gi|5032041 Ras homolog enriched in brain [Homo sapiens]
Length = 184
Score = 34.3 bits (77), Expect = 0.30
Identities = 19/61 (31%), Positives = 32/61 (52%)
Query: 31 KALMTVGKEPFPTIYVDSQKENERWNVISKSQLKNIKKMWHREQMKSESREKKEAEDSLR 90
K L VGK P + V ++K+ VIS + K + + W+ ++S ++E + A D R
Sbjct: 102 KLLDMVGKVQIPIMLVGNKKDLHMERVISYEEGKALAESWNAAFLESSAKENQTAVDVFR 161
Query: 91 R 91
R
Sbjct: 162 R 162
>gi|72534692 5'-nucleotidase domain containing 3 [Homo sapiens]
Length = 548
Score = 34.3 bits (77), Expect = 0.30
Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 5/48 (10%)
Query: 373 IVHELNPNF-QPPKRPFKRMNYSDAIVWLKEHDVKK----EDGTFYEF 415
IV PNF +RPF++MN ++W K H ++K + G YEF
Sbjct: 326 IVQAEKPNFFNDKRRPFRKMNEKGVLLWDKIHKLQKGQIYKQGNLYEF 373
>gi|19923899 coiled-coil domain containing 45 [Homo sapiens]
Length = 821
Score = 33.9 bits (76), Expect = 0.40
Identities = 26/96 (27%), Positives = 48/96 (50%), Gaps = 3/96 (3%)
Query: 22 KEKPFKTGLKALMTVGKEPFPTIYVDSQKENERWNVISKSQLKNIKKMWHREQMKSESRE 81
K P K +L+ + E FP +YV ++ W +Q++ +KK RE +S+ +
Sbjct: 554 KAVPMKVSEHSLLPLMLEQFPFLYVSGPTLSKMWKQ-QIAQVEQLKKEACREN-RSKKKL 611
Query: 82 KKEAEDSLRREKNLEEAKKITIKNDPSLPEPK-CVK 116
+ E E++LRR L K +++ L + K C++
Sbjct: 612 QDEIEEALRRHDLLTTLVKKEYEHNKRLQDFKDCIR 647
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 33.1 bits (74), Expect = 0.67
Identities = 25/104 (24%), Positives = 51/104 (49%), Gaps = 3/104 (2%)
Query: 43 TIYVDSQKENERWNVISKSQLKNIKKMWHREQ-MKSESREKKEAEDSLRR-EKNLEEAKK 100
T+ + ++ E K K +KMW +E+ ++ + + +E E+ +RR EK L E +K
Sbjct: 231 TLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEK 290
Query: 101 ITIKNDPSLPEPKCVKIGALEGYRGQRVKVFGWVHRLRRQGKNL 144
+ + L E K ++ E + Q K++ ++R Q + +
Sbjct: 291 ELREQEKELREQKKLR-EQEEQMQEQEEKMWEQEEKMREQEEKM 333
Score = 32.0 bits (71), Expect = 1.5
Identities = 21/92 (22%), Positives = 46/92 (50%), Gaps = 7/92 (7%)
Query: 60 KSQLKNIKKMWH-----REQMKSESREKK--EAEDSLRREKNLEEAKKITIKNDPSLPEP 112
+ +++ KKMW RE+ K++ +EKK + E+ +R E+ + E +K + + + E
Sbjct: 520 EERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ 579
Query: 113 KCVKIGALEGYRGQRVKVFGWVHRLRRQGKNL 144
+ E R Q K++ +++ Q + +
Sbjct: 580 EEKMQEQEEKMREQEEKMWEQEEKMQEQEEKM 611
Score = 29.6 bits (65), Expect = 7.5
Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 3/86 (3%)
Query: 49 QKENERWNVISKSQLKNIKKMWHREQMKSESREK-KEAEDSLR-REKNLEEAKKITIKND 106
++E W K Q + +KMW +E+ E EK +E E+ ++ +E+ + E ++ +
Sbjct: 629 EQEEMMWEQEEKMQEQE-EKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQE 687
Query: 107 PSLPEPKCVKIGALEGYRGQRVKVFG 132
+ E + G E GQ K++G
Sbjct: 688 EKMREQEEKMRGQEEKMWGQEEKMWG 713
>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
isoform b [Homo sapiens]
Length = 1176
Score = 33.1 bits (74), Expect = 0.67
Identities = 22/81 (27%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
Query: 17 TGDGTKEKPFKTGLKALMTVGKEPFPTIYVDSQKENERWNVISKSQLKNIKKMWHREQMK 76
+G+ T K L+ TV + F ++Y DS +ER + SKS+++ + + E+ +
Sbjct: 246 SGEVTLTKGDPGSLEEWETVVGDDF-SLYYDSYSVDERVDSDSKSEVEALTEQLSEEEEE 304
Query: 77 SESREKKEAEDSLRREKNLEE 97
E E++E E+ E+ +E
Sbjct: 305 EEEEEEEEEEEEEEEEEEEDE 325
>gi|156142197 euchromatic histone-lysine N-methyltransferase 2
isoform a [Homo sapiens]
Length = 1210
Score = 33.1 bits (74), Expect = 0.67
Identities = 22/81 (27%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
Query: 17 TGDGTKEKPFKTGLKALMTVGKEPFPTIYVDSQKENERWNVISKSQLKNIKKMWHREQMK 76
+G+ T K L+ TV + F ++Y DS +ER + SKS+++ + + E+ +
Sbjct: 246 SGEVTLTKGDPGSLEEWETVVGDDF-SLYYDSYSVDERVDSDSKSEVEALTEQLSEEEEE 304
Query: 77 SESREKKEAEDSLRREKNLEE 97
E E++E E+ E+ +E
Sbjct: 305 EEEEEEEEEEEEEEEEEEEDE 325
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 33.1 bits (74), Expect = 0.67
Identities = 19/58 (32%), Positives = 32/58 (55%)
Query: 45 YVDSQKENERWNVISKSQLKNIKKMWHREQMKSESREKKEAEDSLRREKNLEEAKKIT 102
Y E+ER + S+S + +++ HR + K E+ +KE E L +K +EE K+ T
Sbjct: 391 YGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQT 448
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 33.1 bits (74), Expect = 0.67
Identities = 19/58 (32%), Positives = 32/58 (55%)
Query: 45 YVDSQKENERWNVISKSQLKNIKKMWHREQMKSESREKKEAEDSLRREKNLEEAKKIT 102
Y E+ER + S+S + +++ HR + K E+ +KE E L +K +EE K+ T
Sbjct: 391 YGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQT 448
>gi|237649104 bromodomain containing 9 isoform 1 [Homo sapiens]
Length = 597
Score = 32.7 bits (73), Expect = 0.88
Identities = 25/110 (22%), Positives = 45/110 (40%), Gaps = 19/110 (17%)
Query: 23 EKPFKTGLKALMTVGKEPFPTI--------YVDSQKENERWNVISKSQLKNIKKMWHREQ 74
+KP + LK ++ VG + Y D + ++ER K + K KK +
Sbjct: 21 DKPLEKPLKLVLKVGGSEVTELSGSGHDSSYYDDRSDHERERHKEKKKKKK-KKSEKEKH 79
Query: 75 MKSESREKKEAEDSLRREK----------NLEEAKKITIKNDPSLPEPKC 114
+ E R K++ E +RE+ + + KK+ ++ P P C
Sbjct: 80 LDDEERRKRKEEKKRKREREHCDTEGEADDFDPGKKVEVEPPPDRPVRAC 129
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 32.7 bits (73), Expect = 0.88
Identities = 16/55 (29%), Positives = 28/55 (50%)
Query: 46 VDSQKENERWNVISKSQLKNIKKMWHREQMKSESREKKEAEDSLRREKNLEEAKK 100
++ QKE R + + + ++ REQ + E EK+ E+ RR K EE ++
Sbjct: 399 IEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRR 453
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 32.7 bits (73), Expect = 0.88
Identities = 16/55 (29%), Positives = 28/55 (50%)
Query: 46 VDSQKENERWNVISKSQLKNIKKMWHREQMKSESREKKEAEDSLRREKNLEEAKK 100
++ QKE R + + + ++ REQ + E EK+ E+ RR K EE ++
Sbjct: 399 IEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRR 453
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 32.7 bits (73), Expect = 0.88
Identities = 16/55 (29%), Positives = 28/55 (50%)
Query: 46 VDSQKENERWNVISKSQLKNIKKMWHREQMKSESREKKEAEDSLRREKNLEEAKK 100
++ QKE R + + + ++ REQ + E EK+ E+ RR K EE ++
Sbjct: 399 IEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRR 453
>gi|167466219 dpy-19-like 4 [Homo sapiens]
Length = 723
Score = 32.7 bits (73), Expect = 0.88
Identities = 26/127 (20%), Positives = 49/127 (38%), Gaps = 8/127 (6%)
Query: 281 GATLFKLDYFGEEAFLTQSSQLYLETCLPALGDVFCIAQSYRAEQSRTRRHLAEYTHVEA 340
G + L + ++ L ++ +Y + D++ I SY+A +
Sbjct: 596 GWMVTSLPLYNDDDLLKRNENIYQIYSKRSAEDIYKILTSYKANYLIVEDAICNEVGPMR 655
Query: 341 ECPFLTFDDLLNRLEDLVCDVVDRILKSPAGSIVHELNPNFQPPKRPFKRMNYSDAIVWL 400
C D+ N +VC+ D++ S G HE+ N+ P +NY + W
Sbjct: 656 GCRVKDLLDIANG--HMVCEEGDKLTYSKYGRFCHEVKINYSP------YVNYFTRVYWN 707
Query: 401 KEHDVKK 407
+ + V K
Sbjct: 708 RSYFVYK 714
>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform
1 [Homo sapiens]
Length = 1722
Score = 32.7 bits (73), Expect = 0.88
Identities = 18/54 (33%), Positives = 33/54 (61%), Gaps = 1/54 (1%)
Query: 48 SQKENERWNVISKSQLKNIKKMWHREQMKSESREKKEAEDSLRREKNLEEAKKI 101
+Q+ E+ I + + +N K++ +++K E +++KE E+ RREK EE K I
Sbjct: 318 AQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKE-EERKRREKEYEEKKNI 370
>gi|120953243 leucine-rich repeats and IQ motif containing 1 isoform
2 [Homo sapiens]
Length = 1336
Score = 32.7 bits (73), Expect = 0.88
Identities = 18/54 (33%), Positives = 33/54 (61%), Gaps = 1/54 (1%)
Query: 48 SQKENERWNVISKSQLKNIKKMWHREQMKSESREKKEAEDSLRREKNLEEAKKI 101
+Q+ E+ I + + +N K++ +++K E +++KE E+ RREK EE K I
Sbjct: 318 AQEWKEKEAKIRQKEEENRKRLEEEQRIKEERKKQKE-EERKRREKEYEEKKNI 370
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 32.3 bits (72), Expect = 1.1
Identities = 20/96 (20%), Positives = 46/96 (47%), Gaps = 1/96 (1%)
Query: 49 QKENERWNVISKSQLKNIKKMWHREQMKSESREKKEAEDSLRREKNLEEAKKITIKNDPS 108
Q++ E+ + + +KMW +E+ E + E ++ L + ++E +KI + +
Sbjct: 737 QEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKM 796
Query: 109 LPEPKCVKIGALEGYRGQRVKVFGWVHRLRRQGKNL 144
+ + ++ G E RGQ K+ G ++ Q + +
Sbjct: 797 RDQEEKMR-GQEEKMRGQEEKMRGQEEKMWGQEEKM 831
Score = 32.0 bits (71), Expect = 1.5
Identities = 24/104 (23%), Positives = 49/104 (47%), Gaps = 3/104 (2%)
Query: 43 TIYVDSQKENERWNVISKSQLKNIKKMWHREQ--MKSESREKKEAEDSLRREKNLEEAKK 100
T+ + ++ E K K +KMW +E+ + E + +++ E R+EK L E +K
Sbjct: 269 TLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEK 328
Query: 101 ITIKNDPSLPEPKCVKIGALEGYRGQRVKVFGWVHRLRRQGKNL 144
+ + L E K ++ E + Q K++ ++R Q + +
Sbjct: 329 ELREQEKELREQKELR-EQEEQMQEQEEKMWEQEEKMREQEEKM 371
Score = 29.3 bits (64), Expect = 9.7
Identities = 16/57 (28%), Positives = 34/57 (59%), Gaps = 6/57 (10%)
Query: 49 QKENERWNVISKSQLKNIKKMWHRE---QMKSESREKK--EAEDSLRREKNLEEAKK 100
++E++ W K + + +KMW +E + K++ +EKK + E+ +R E+ + E +K
Sbjct: 541 EQEDQMWEQEEKMRDQE-QKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREK 596
>gi|4503179 oral-facial-digital syndrome 1 [Homo sapiens]
Length = 1012
Score = 32.3 bits (72), Expect = 1.1
Identities = 20/64 (31%), Positives = 34/64 (53%), Gaps = 6/64 (9%)
Query: 46 VDSQKENERWNVISKSQLKNIKKMWHREQMKSES---REKKEAEDSLRREKNLEEAKKIT 102
++ QKE E+ I + Q+K ++ R Q + RE++E E + K +EE+ KI
Sbjct: 873 IEEQKEEEK---IREQQVKERRQREERRQSNLQEVLERERRELEKLYQERKMIEESLKIK 929
Query: 103 IKND 106
IK +
Sbjct: 930 IKKE 933
>gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo
sapiens]
Length = 1499
Score = 32.0 bits (71), Expect = 1.5
Identities = 21/86 (24%), Positives = 36/86 (41%), Gaps = 2/86 (2%)
Query: 39 EPFPTIYVDSQKENERWNVISKSQLKNIKKMWHREQMKSESREKKEAEDSLRREKNLEEA 98
EP + +E ++V S I + R K++S DS +LE
Sbjct: 1089 EPMDAVVKPRNEEENIYSVPHDSTQGKIITI--RNINKAQSNGSGNGSDSEMDTSSLERG 1146
Query: 99 KKITIKNDPSLPEPKCVKIGALEGYR 124
+K++I + P L +C ++G YR
Sbjct: 1147 RKVSIVSKPVLYRTRCTRLGRFASYR 1172
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 32.0 bits (71), Expect = 1.5
Identities = 20/55 (36%), Positives = 33/55 (60%), Gaps = 6/55 (10%)
Query: 50 KENERWNVISKSQLKNIKKMWHREQMKSESREK-KEAEDSLR--REKNLEEAKKI 101
+ENE WN +++ Q +KMW +E+ E EK +E E+ +R EK E+ +K+
Sbjct: 347 EENELWNRLNQQQ---EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 398
>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
sapiens]
Length = 929
Score = 32.0 bits (71), Expect = 1.5
Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 5/66 (7%)
Query: 50 KENERWNVISKSQLKNIKKMWHREQMKSESREKKEAEDSLRREKNLEEAKKITIKNDPSL 109
KE E+ K K KK +E+ K E +KE + +REK E+ K IK +P
Sbjct: 697 KEKEK-----KKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEKEKHKHEKIKVEPVA 751
Query: 110 PEPKCV 115
P V
Sbjct: 752 LAPSPV 757
>gi|75677576 dyslexia susceptibility 1 candidate 1 isoform c [Homo
sapiens]
Length = 381
Score = 32.0 bits (71), Expect = 1.5
Identities = 30/99 (30%), Positives = 49/99 (49%), Gaps = 15/99 (15%)
Query: 11 REGSDATGDGTKEKPFKTGLKALMTVGKEPFPTIYVDSQKENERWNVISKSQLKNIKKM- 69
+E ++A +E K L +M + +E I + KENER +K K +
Sbjct: 112 KEATEAKAAAKREDQ-KYALSVMMKIEEEERKKI--EDMKENER--------IKATKALE 160
Query: 70 -WHREQMKSESREKKEAEDSL-RREKNL-EEAKKITIKN 105
W Q K+E ++K + E+ L ++EK + EE KKI K+
Sbjct: 161 AWKEYQRKAEEQKKIQREEKLCQKEKQIKEERKKIKYKS 199
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.138 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,654,590
Number of Sequences: 37866
Number of extensions: 1065023
Number of successful extensions: 4038
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 66
Number of HSP's that attempted gapping in prelim test: 3799
Number of HSP's gapped (non-prelim): 265
length of query: 548
length of database: 18,247,518
effective HSP length: 107
effective length of query: 441
effective length of database: 14,195,856
effective search space: 6260372496
effective search space used: 6260372496
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.