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Search of human proteins with 4758626
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758626 potassium large conductance calcium-activated
channel, subfamily M, beta member 1 [Homo sapiens]
(191 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758626 potassium large conductance calcium-activated channel... 389 e-108
gi|31317295 calcium-activated potassium channel beta 2 subunit [... 164 4e-41
gi|5031823 calcium-activated potassium channel beta 2 subunit [H... 164 4e-41
gi|25952095 calcium-activated potassium channel beta 3 subunit i... 94 9e-20
gi|25952105 calcium-activated potassium channel beta 3 subunit i... 94 9e-20
gi|25952102 calcium-activated potassium channel beta 3 subunit i... 94 9e-20
gi|25952099 calcium-activated potassium channel beta 3 subunit i... 94 9e-20
gi|26051275 calcium-activated potassium channel beta 4 subunit [... 49 2e-06
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 28 3.7
gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens] 28 3.7
gi|239757751 PREDICTED: hypothetical protein [Homo sapiens] 28 3.7
gi|46094058 3'-phosphoadenosine 5'-phosphosulfate synthase 1 [Ho... 28 4.8
gi|22024390 potassium voltage-gated channel, subfamily H, member... 27 8.2
gi|27886646 potassium voltage-gated channel, subfamily H, member... 27 8.2
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 27 8.2
gi|41393554 LUC7-like isoform b [Homo sapiens] 27 8.2
gi|8922297 LUC7-like isoform a [Homo sapiens] 27 8.2
gi|42476169 Paf1, RNA polymerase II associated factor, homolog [... 27 8.2
gi|53793673 olfactory receptor, family 10, subfamily C, member 1... 27 8.2
>gi|4758626 potassium large conductance calcium-activated channel,
subfamily M, beta member 1 [Homo sapiens]
Length = 191
Score = 389 bits (998), Expect = e-108
Identities = 191/191 (100%), Positives = 191/191 (100%)
Query: 1 MVKKLVMAQKRGETRALCLGVTMVVCAVITYYILVTTVLPLYQKSVWTQESKCHLIETNI 60
MVKKLVMAQKRGETRALCLGVTMVVCAVITYYILVTTVLPLYQKSVWTQESKCHLIETNI
Sbjct: 1 MVKKLVMAQKRGETRALCLGVTMVVCAVITYYILVTTVLPLYQKSVWTQESKCHLIETNI 60
Query: 61 RDQEELKGKKVPQYPCLWVNVSAAGRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADV 120
RDQEELKGKKVPQYPCLWVNVSAAGRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADV
Sbjct: 61 RDQEELKGKKVPQYPCLWVNVSAAGRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADV 120
Query: 121 EKVRAKFQEQQVFYCFSAPRGNETSVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMVKS 180
EKVRAKFQEQQVFYCFSAPRGNETSVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMVKS
Sbjct: 121 EKVRAKFQEQQVFYCFSAPRGNETSVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMVKS 180
Query: 181 NQYLSILAAQK 191
NQYLSILAAQK
Sbjct: 181 NQYLSILAAQK 191
>gi|31317295 calcium-activated potassium channel beta 2 subunit
[Homo sapiens]
Length = 235
Score = 164 bits (415), Expect = 4e-41
Identities = 83/193 (43%), Positives = 123/193 (63%), Gaps = 8/193 (4%)
Query: 3 KKLVMAQKRGETRALCLGVTMVVCAVITYYILVTTVLPLYQKSVWTQESKCHLIETNIRD 62
+K V A K GE RA+ LG+ M+VC+++ Y++L T+L Y +SVWT+ES+C L+ +I +
Sbjct: 34 RKTVTALKAGEDRAILLGLAMMVCSIMMYFLLGITLLRSYMQSVWTEESQCTLLNASITE 93
Query: 63 QEELKGK------KVPQYPCL--WVNVSAAGRWAVLYHTEDTRDQNQQCSYIPGSVDNYQ 114
K+ QYPCL +VN++++G +LYHTE+T NQ+CSYIP N++
Sbjct: 94 TFNCSFSCGPDCWKLSQYPCLQVYVNLTSSGEKLLLYHTEETIKINQKCSYIPKCGKNFE 153
Query: 115 TARADVEKVRAKFQEQQVFYCFSAPRGNETSVLFQRLYGPQALLFSLFWPTFLLTGGLLI 174
+ + V V F++ Q F C+S P GN+ SV+ +LY L SLFWPT ++ GG+ I
Sbjct: 154 ESMSLVNVVMENFRKYQHFSCYSDPEGNQKSVILTKLYSSNVLFHSLFWPTCMMAGGVAI 213
Query: 175 IAMVKSNQYLSIL 187
+AMVK QYLS+L
Sbjct: 214 VAMVKLTQYLSLL 226
>gi|5031823 calcium-activated potassium channel beta 2 subunit [Homo
sapiens]
Length = 235
Score = 164 bits (415), Expect = 4e-41
Identities = 83/193 (43%), Positives = 123/193 (63%), Gaps = 8/193 (4%)
Query: 3 KKLVMAQKRGETRALCLGVTMVVCAVITYYILVTTVLPLYQKSVWTQESKCHLIETNIRD 62
+K V A K GE RA+ LG+ M+VC+++ Y++L T+L Y +SVWT+ES+C L+ +I +
Sbjct: 34 RKTVTALKAGEDRAILLGLAMMVCSIMMYFLLGITLLRSYMQSVWTEESQCTLLNASITE 93
Query: 63 QEELKGK------KVPQYPCL--WVNVSAAGRWAVLYHTEDTRDQNQQCSYIPGSVDNYQ 114
K+ QYPCL +VN++++G +LYHTE+T NQ+CSYIP N++
Sbjct: 94 TFNCSFSCGPDCWKLSQYPCLQVYVNLTSSGEKLLLYHTEETIKINQKCSYIPKCGKNFE 153
Query: 115 TARADVEKVRAKFQEQQVFYCFSAPRGNETSVLFQRLYGPQALLFSLFWPTFLLTGGLLI 174
+ + V V F++ Q F C+S P GN+ SV+ +LY L SLFWPT ++ GG+ I
Sbjct: 154 ESMSLVNVVMENFRKYQHFSCYSDPEGNQKSVILTKLYSSNVLFHSLFWPTCMMAGGVAI 213
Query: 175 IAMVKSNQYLSIL 187
+AMVK QYLS+L
Sbjct: 214 VAMVKLTQYLSLL 226
>gi|25952095 calcium-activated potassium channel beta 3 subunit
isoform d [Homo sapiens]
Length = 279
Score = 93.6 bits (231), Expect = 9e-20
Identities = 59/189 (31%), Positives = 94/189 (49%), Gaps = 15/189 (7%)
Query: 12 GETRALCLGVTMVVCAVITYYILVTTVLPLYQKSVWTQESKCHLIETNIRDQ-------- 63
GE RA+ LG M+ +V+ +++L TT+L + S+ +ES C I T+I D
Sbjct: 54 GEDRAVMLGFAMMGFSVLMFFLLGTTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTC 113
Query: 64 -EELKGKKVPQYPCL--WVNVSAAGRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADV 120
G+ +YPCL +VN+S G+ A+L++ E+ N +C Y P +
Sbjct: 114 GVHCHGQG--KYPCLQVFVNLSHPGQKALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSA 171
Query: 121 EKVRAKFQEQQ--VFYCFSAPRGNETSVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMV 178
++ F + F CF +P V+ + Y A+ LFWP+ L GG LI+ MV
Sbjct: 172 LDIKEFFDHKNGTPFSCFYSPASQSEDVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMV 231
Query: 179 KSNQYLSIL 187
+ Q+LS+L
Sbjct: 232 RLTQHLSLL 240
>gi|25952105 calcium-activated potassium channel beta 3 subunit
isoform c [Homo sapiens]
Length = 275
Score = 93.6 bits (231), Expect = 9e-20
Identities = 59/189 (31%), Positives = 94/189 (49%), Gaps = 15/189 (7%)
Query: 12 GETRALCLGVTMVVCAVITYYILVTTVLPLYQKSVWTQESKCHLIETNIRDQ-------- 63
GE RA+ LG M+ +V+ +++L TT+L + S+ +ES C I T+I D
Sbjct: 50 GEDRAVMLGFAMMGFSVLMFFLLGTTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTC 109
Query: 64 -EELKGKKVPQYPCL--WVNVSAAGRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADV 120
G+ +YPCL +VN+S G+ A+L++ E+ N +C Y P +
Sbjct: 110 GVHCHGQG--KYPCLQVFVNLSHPGQKALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSA 167
Query: 121 EKVRAKFQEQQ--VFYCFSAPRGNETSVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMV 178
++ F + F CF +P V+ + Y A+ LFWP+ L GG LI+ MV
Sbjct: 168 LDIKEFFDHKNGTPFSCFYSPASQSEDVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMV 227
Query: 179 KSNQYLSIL 187
+ Q+LS+L
Sbjct: 228 RLTQHLSLL 236
>gi|25952102 calcium-activated potassium channel beta 3 subunit
isoform b [Homo sapiens]
Length = 257
Score = 93.6 bits (231), Expect = 9e-20
Identities = 59/189 (31%), Positives = 94/189 (49%), Gaps = 15/189 (7%)
Query: 12 GETRALCLGVTMVVCAVITYYILVTTVLPLYQKSVWTQESKCHLIETNIRDQ-------- 63
GE RA+ LG M+ +V+ +++L TT+L + S+ +ES C I T+I D
Sbjct: 32 GEDRAVMLGFAMMGFSVLMFFLLGTTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTC 91
Query: 64 -EELKGKKVPQYPCL--WVNVSAAGRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADV 120
G+ +YPCL +VN+S G+ A+L++ E+ N +C Y P +
Sbjct: 92 GVHCHGQG--KYPCLQVFVNLSHPGQKALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSA 149
Query: 121 EKVRAKFQEQQ--VFYCFSAPRGNETSVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMV 178
++ F + F CF +P V+ + Y A+ LFWP+ L GG LI+ MV
Sbjct: 150 LDIKEFFDHKNGTPFSCFYSPASQSEDVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMV 209
Query: 179 KSNQYLSIL 187
+ Q+LS+L
Sbjct: 210 RLTQHLSLL 218
>gi|25952099 calcium-activated potassium channel beta 3 subunit
isoform a [Homo sapiens]
Length = 277
Score = 93.6 bits (231), Expect = 9e-20
Identities = 59/189 (31%), Positives = 94/189 (49%), Gaps = 15/189 (7%)
Query: 12 GETRALCLGVTMVVCAVITYYILVTTVLPLYQKSVWTQESKCHLIETNIRDQ-------- 63
GE RA+ LG M+ +V+ +++L TT+L + S+ +ES C I T+I D
Sbjct: 52 GEDRAVMLGFAMMGFSVLMFFLLGTTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTC 111
Query: 64 -EELKGKKVPQYPCL--WVNVSAAGRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADV 120
G+ +YPCL +VN+S G+ A+L++ E+ N +C Y P +
Sbjct: 112 GVHCHGQG--KYPCLQVFVNLSHPGQKALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSA 169
Query: 121 EKVRAKFQEQQ--VFYCFSAPRGNETSVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMV 178
++ F + F CF +P V+ + Y A+ LFWP+ L GG LI+ MV
Sbjct: 170 LDIKEFFDHKNGTPFSCFYSPASQSEDVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMV 229
Query: 179 KSNQYLSIL 187
+ Q+LS+L
Sbjct: 230 RLTQHLSLL 238
>gi|26051275 calcium-activated potassium channel beta 4 subunit
[Homo sapiens]
Length = 210
Score = 49.3 bits (116), Expect = 2e-06
Identities = 43/190 (22%), Positives = 79/190 (41%), Gaps = 16/190 (8%)
Query: 13 ETRALCLGVTMVVCAVITYYILVTTVLPLYQKSVWTQESKCHLI---------ETNIRDQ 63
E +++ LG+ +++ V++ +I L + + E+ C ++ E
Sbjct: 14 EDKSIRLGLFLIISGVVSLFIFGFCWLSPALQDLQATEANCTVLSVQQIGEVFECTFTCG 73
Query: 64 EELKGKKVPQYPCL--WVNVSAAGRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADVE 121
+ +G QYPC+ +VN S + A+L+ E N +CSYIP Q V
Sbjct: 74 ADCRGTS--QYPCVQVYVNNSESNSRALLHSDEHQLLTNPKCSYIPPCKRENQKNLESVM 131
Query: 122 KVRAKFQEQ---QVFYCFSAPRGNETSVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMV 178
+ ++++ Q F C+ VL R + LL WP G+LI+ +
Sbjct: 132 NWQQYWKDEIGSQPFTCYFNQHQRPDDVLLHRTHDEIVLLHCFLWPLVTFVVGVLIVVLT 191
Query: 179 KSNQYLSILA 188
+ L++ A
Sbjct: 192 ICAKSLAVKA 201
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 28.5 bits (62), Expect = 3.7
Identities = 12/23 (52%), Positives = 15/23 (65%)
Query: 43 QKSVWTQESKCHLIETNIRDQEE 65
++ VW QE K H E IR+QEE
Sbjct: 494 EEKVWRQEEKMHDQEEKIREQEE 516
>gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens]
Length = 467
Score = 28.5 bits (62), Expect = 3.7
Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
Query: 97 RDQNQQCSYIPGSVDNYQTARADVE-KVRAKFQEQQVFYCFSAPRGNETSVLFQRL 151
R NQ+ PG + A +E KV A FQ++ F+ FS PR ++ QR+
Sbjct: 397 RYDNQRQFMEPGYPKSISGAFPGIESKVDAVFQQEHFFHVFSGPRYYAFDLIAQRV 452
>gi|239757751 PREDICTED: hypothetical protein [Homo sapiens]
Length = 327
Score = 28.5 bits (62), Expect = 3.7
Identities = 11/21 (52%), Positives = 13/21 (61%)
Query: 76 CLWVNVSAAGRWAVLYHTEDT 96
CL +SA GRWAV +H T
Sbjct: 69 CLKFEISARGRWAVFHHQPST 89
>gi|46094058 3'-phosphoadenosine 5'-phosphosulfate synthase 1 [Homo
sapiens]
Length = 624
Score = 28.1 bits (61), Expect = 4.8
Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 4/45 (8%)
Query: 44 KSVWTQESKCHLIETNIRDQEELKGKKVPQYPCLWVNVSAAGRWA 88
K ++ E+K HL +T D E L K+ + WV V A G WA
Sbjct: 235 KELYVPENKLHLAKT---DAETLPALKINKVDMQWVQVLAEG-WA 275
>gi|22024390 potassium voltage-gated channel, subfamily H, member 5
isoform 1 [Homo sapiens]
Length = 988
Score = 27.3 bits (59), Expect = 8.2
Identities = 19/66 (28%), Positives = 29/66 (43%), Gaps = 7/66 (10%)
Query: 91 YHTEDTRDQNQQCSYIPGSVDNYQTARADVEKVRAKFQEQQVFYCFSA--PRGNETSVLF 148
YH D ++ CS++ G + + +T +EKVR F + CF + N T V F
Sbjct: 53 YHRADVMQKSSTCSFMYGELTDKKT----IEKVRQTFDNYE-SNCFEVLLYKKNRTPVWF 107
Query: 149 QRLYGP 154
P
Sbjct: 108 YMQIAP 113
>gi|27886646 potassium voltage-gated channel, subfamily H, member 5
isoform 3 [Homo sapiens]
Length = 611
Score = 27.3 bits (59), Expect = 8.2
Identities = 19/66 (28%), Positives = 29/66 (43%), Gaps = 7/66 (10%)
Query: 91 YHTEDTRDQNQQCSYIPGSVDNYQTARADVEKVRAKFQEQQVFYCFSA--PRGNETSVLF 148
YH D ++ CS++ G + + +T +EKVR F + CF + N T V F
Sbjct: 53 YHRADVMQKSSTCSFMYGELTDKKT----IEKVRQTFDNYE-SNCFEVLLYKKNRTPVWF 107
Query: 149 QRLYGP 154
P
Sbjct: 108 YMQIAP 113
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 27.3 bits (59), Expect = 8.2
Identities = 11/23 (47%), Positives = 15/23 (65%)
Query: 43 QKSVWTQESKCHLIETNIRDQEE 65
++ +W QE K H E IR+QEE
Sbjct: 556 EEKMWRQEEKMHDQEEKIREQEE 578
>gi|41393554 LUC7-like isoform b [Homo sapiens]
Length = 371
Score = 27.3 bits (59), Expect = 8.2
Identities = 15/32 (46%), Positives = 19/32 (59%)
Query: 108 GSVDNYQTARADVEKVRAKFQEQQVFYCFSAP 139
G+VD Q +VEKVRAK +E + Y S P
Sbjct: 147 GNVDESQKILMEVEKVRAKKKEAEEEYRNSMP 178
>gi|8922297 LUC7-like isoform a [Homo sapiens]
Length = 325
Score = 27.3 bits (59), Expect = 8.2
Identities = 15/32 (46%), Positives = 19/32 (59%)
Query: 108 GSVDNYQTARADVEKVRAKFQEQQVFYCFSAP 139
G+VD Q +VEKVRAK +E + Y S P
Sbjct: 147 GNVDESQKILMEVEKVRAKKKEAEEEYRNSMP 178
>gi|42476169 Paf1, RNA polymerase II associated factor, homolog
[Homo sapiens]
Length = 531
Score = 27.3 bits (59), Expect = 8.2
Identities = 14/43 (32%), Positives = 23/43 (53%), Gaps = 3/43 (6%)
Query: 97 RDQNQQCSYIPGSVDNYQTARA---DVEKVRAKFQEQQVFYCF 136
RDQ ++ Y P V +Y+ AR +V+ +K E+ F+ F
Sbjct: 273 RDQEEEMDYAPDDVYDYKIAREYNWNVKNKASKGYEENYFFIF 315
>gi|53793673 olfactory receptor, family 10, subfamily C, member 1
[Homo sapiens]
Length = 312
Score = 27.3 bits (59), Expect = 8.2
Identities = 16/39 (41%), Positives = 22/39 (56%), Gaps = 2/39 (5%)
Query: 148 FQRLYGPQALLFSLFWPTFLLT--GGLLIIAMVKSNQYL 184
F L Q LLFS+F +LLT G LI+ +V ++ L
Sbjct: 16 FSHLADLQGLLFSVFLTIYLLTVAGNFLIVVLVSTDAAL 54
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.135 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,712,679
Number of Sequences: 37866
Number of extensions: 275930
Number of successful extensions: 896
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 851
Number of HSP's gapped (non-prelim): 38
length of query: 191
length of database: 18,247,518
effective HSP length: 96
effective length of query: 95
effective length of database: 14,612,382
effective search space: 1388176290
effective search space used: 1388176290
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.